OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11024707	In autism, there often is a general speech delay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "autism", ",", "there", "often", "is", "a", "general", "speech", "delay", "." ] ...
PMC11754432	Subsequently, the secretion of cytokines was analysed by cytometric bead array (Fig. 2F–J).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "the", "secretion", ...
PMC11532793	While both edgeR and Swish accept as input RNA-seq quantification from both kallisto and Salmon, with either bootstrap or Gibbs sampling, sleuth accepts RNA-seq quantification output only from kallisto.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11335267	This study highlights the crucial role for Alx3 in governing food intake, energy homeostasis, and metabolic nutrient partitioning, thereby influencing body mass composition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9878278	ZIKV titers in the supernatants from siCtrl and double knock-down (DKD) with siMDA5 and siRIG-I cells were determined by plaque assay at 48 hpi and expressed as PFU/mL supernatant. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC7759933	In our study, the proliferation of cells and their distribution within the cell cycle of spheroids with the initial density of 3000 and 6000 cells/spheroid were determined by flow cytometry over the time of cultivation, with simultaneous detection of the fluorescent signals of FITC corresponding to the proliferation ma...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786767	After washing with PBS, AlexaFluor-555-conjugated tyramide was diluted (1:50) in amplification diluent and applied to the cells for 15 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After",...
PMC11803149	In some experiments, CD8 T cells were activated with Dynabeads Mouse T-activator CD3/CD28 beads (Gibco, 11456D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "some", "experiments", ...
PMC11615743	Comparatively, the control cell lines with single‐positive or dual‐negative recognition patterns for Sgc8 and TC01 (such as human Burkitt's lymphoma cells, Ramos; human acute T leukemia cells, Jurkat; and human erythromyeloblastoid leukemia cells, K562 ) exhibited minimal fluorescence enhancement, with a signal gain lo...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11762280	Primary antibodies against phospho-MLKL (Ser358, #ab187091 for human), GSDMD (#ab209845 for mouse), NLRP3 (#ab263899), MPO (#ab208670), MMP-9 (#ab283575), CD4 (#ab183685), and CD8 (#ab217344) were from Abcam (Cambridge, MA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10470467	Finally, to evaluate the signature’s generalization ability, we used the other independent dataset, GSE63157, as validation data and followed the same procedure as described above.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Of interest, when Ddx41-derived BM cells were co-transplanted with Ddx41-derived BM cells, some of the recipient mice showed impaired hematopoiesis, suggesting the presence of a non-cell autonomous effect of Ddx41 cells on Ddx41 cells.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10440586	The GSEA plot in the hypoxia genes set of the TCGA dataset. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "GSEA", "plot", "in", "the", "hypoxia", "genes", "set", "of", ...
PMC10669966	This final IST reference list contained a total of 2754 genes and was used as an exclusion list, to eliminate non-LPS-specific genes from the LPS-subtype differential-gene-expression analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11529598	D. Cell cycle analysis was performed on miR-3154 sponge transfected cells and control cells using flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D.", "Cell", "cycle", "analysis", "was", "p...
PMC11727145	However, in our experiments, the K14 protein was not present.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "in", "our", "experiments", ",", "the", "K14", "protein", "...
PMC11695546	Earlier every test, the stock solutions were diluted by a 20 mM sodium phosphate buffer solution (pH 7.6) to a range of concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10810426	Knockdown efficacy is shown in the middle panel and effects on cell viability in the bottom panel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Knockdown", "efficacy", "is", "shown", "in", ...
PMC9429973	Summary/Conclusion: This study draws attention to the level of anxiety in patients with hematological malignancies of the COVID-19 pandemic.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion", ":", "T...
PMC11743414	Previous reports have shown that FHL1 acts through various mechanisms, including the inhibition of tumor cell growth through the tumor growth factor-β-like signaling pathway and negative regulation of the G2/M transition mitotic cell cycle .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7812570	After incubation for 24 h, the transduced cells were extensively washed and cultured in complete DMEM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "incubation", "for", "24", "h", ","...
PMC9429973	Type A inserts were found in 48 out of 78 cases (61.5%), type B - in 2 out of 78 (4.5%), and type D - 15.4% (12 out of 78).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9848491	IC50 of JNK inhibitor VIII high and low risk groups. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IC50", "of", "JNK", "inhibitor", "VIII", "high", "and", "low", "risk", "groups", ...
PMC11206251	Compounds with anti-HCC effects include glabridin , baohuoside I , kaempferol , isorhamnetin , morin hydrate , kaempferitrin , genistein , pectolinarigenin , quercetin , luteolin , tangeretin , calycosin , and hyperin .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11395280	Under homeostatic conditions, CCR7 is sulfonated on tyrosine residues that promote interaction with CCL19 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Under", "homeostatic", "conditions", ",", "CCR7", "is", "su...
PMC11509309	After 24 h, the medium was replaced with a culture medium containing 0.45 µg/mL tunicamycin (Tm, Sigma Aldrich, Saint-Louis, MO, USA, #SML1287) and concentrations of molecules indicated on each figure or DMSO as a negative control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	To ensure TatDE cleavage is restricted to HIV-1 proviral DNA, we investigated the potential for aberrant indels at off-target loci in the human genome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9841531	A Knoevenagel condensation with methyl cyanoacetate revealed 2-(3-(2-cyano-3-methoxy-3-oxoprop-1-en-1-yl)-1H-indol-1-yl) acetic acid (16).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Knoevenagel", "condensation", "with", "methyl", "cyanoacetate", "...
PMC11380454	We recently described the unique ability of AS101 to regulate cellular VLA-4 activity via redox modulation of vicinal thiols on the exofacial domain of the VLA-4 integrin 29.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6133382	The reaction was quenched by adding water (1 mL), and the permethylated N-glycans were extracted by organic phase separation using dichloromethane (2 mL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740907	The current research’s findings corroborated those of a previous study that found that hydrolysates of fenugreek protein inhibited the proliferation of colorectal cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11089031	C IHC staining of ccRCC cancer tissue (showing the results of half of the samples, n = 29; total number = 58).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11723947	1Treg are less effective in regulating allogeneic responses mediated by HP1α-deficient T cells than by their wild-type counterparts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "1Treg", "are", "less", "effective", "i...
PMC11185260	When siRNA was encapsulated in scL nanocomplex, the serum stability of siRNA was significantly improved that intact scL-siRNA is clearly present in circulation for at least 24h after an intravenous administration in mice, while free siRNA without delivery system was undetectable at 3h in blood (unpublished data), sugge...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Proportion of patients treated with CIT tended to diminish with subsequent LOT, whereas the proportion treated with ibrutinib tended to increase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Proportion", ...
PMC9027909	Another study by the same team, which was performed in Caco-2 cell line, suggested that ST7 changed the permeability and tight junction localization, which that led to disruption of the intestinal barrier .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721096	Therefore, it is of great significance to discover safe and effective tyrosinase inhibitors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "it", "is", "of", "great", "significance", "to"...
PMC9019892	Effect of Nintedanib and Imatinib in GIST‐882 mouse xenograft models in vivo. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Effect", "of", "Nintedanib", "and", "Imatinib", "in", "GIST‐882", "mouse", ...
PMC10969097	Recently, four new characteristics have been proposed as significant additions to our understanding of cancer and its microenvironment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recently", ",", "four", "new", ...
PMC9429973	Evaluable pts included 26 PON-pretreated and 19 PON-naive pts; 34.6% and 68.4%, respectively, achieved MMR by the cutoff date (Table).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7553912	Immunofluorescence staining for OSM (a) or OSMRβ (d, g, j, m) is shown in the left line (red).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10595704	Their capability to cross physiological barriers was assessed by Parallel Artificial Membrane Permeability Assay (PAMPA) and Caco-2 cell monolayer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Their", "capab...
PMC9429973	Our previous analysis of whole exome germline data from 895 MM patients in the MMRF CoMMpass dataset showed ~8% of MM patients carry a PGV in a hereditary cancer gene (HCG), and identified shared characteristics among PGV carriers including younger age at diagnosis, higher likelihood of having family history of hematol...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672617	Therefore, the synthesized ionic compounds and hybrid molecules based on lithocholic acid are more “soft” dissociators than, for example, the well-known and widely used CCCP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742047	A higher degree of lipid compound alteration following CBD administration was observed in the K-562 cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "A", "higher", "degree", "of", "lipid", ...
PMC10158546	ReN cells were seeded and cultured in complete growth medium for 2–3 days until they reached confluence.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ReN", "cells", "were", "seeded", "and", ...
PMC11678130	Before the application of the staining protocol, the cells were fixed with 4% paraformaldehyde for 15 min at room temperature, permeabilized with 0.1% Triton-X for 15 min at room temperature, and treated with a 1% BSA solution in PBS for 45 min at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750165	Maintenance of neural progenitors requires Notch signaling in vertebrate development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Maintenance", "of", "neural", "progenitors", "requires", "Notch", "signaling", "in", "vertebrate", ...
PMC10976516	Of 21 patients with >6 months follow-up 7 had PFS ≥6 months (33.3%).NCT00998192Gong et al.SenecavirusSeneca Valley virus (NTX-010)NTX-010 after 4 cycles of platinum-based chemotherapyIISystemic i.v.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612315	d Effects of intraplantar administration of exendin 9–39 (5 and 10 μg) and BCTC (0.5 μg) on CAP (1.6 μg)-induced acute licking time (mean ± S.E.M., n = 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9412887	Since ICB are inherent to T cells, lymphocytes and not cancer cells are the target cells of ICB.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since", "ICB", "are", "inherent",...
PMC11519583	It is well established that intercellular crosstalk between SCs and MPs plays a critical role in regulating skeletal muscle maintenance and regeneration .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", ...
PMC10376064	Furthermore, drug repurposing to treat neurodegenerative diseases is highly encouraged by the European Medical Agency (EMA, Amsterdam, Nederlands) and the Federal Drug Agency (FDA, Silver Springs, MD, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9325715	Generally, the appearance of the bands corresponding to more than one functional group in the same region is the main drawback of spectroscopy in the infrared range.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665555	For stable Cas9-expressing cells, we used a lentivirus transfection method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "stable", "Cas9-expressing", "cells", ",", "we", "used", "a", "lentivirus", "tr...
PMC11684269	However, in type 2 diabetes (T2D) individuals, hyperglycemia impairs memory CD8 T cells by insulin-derived GLUT1 upregulation and enhanced glucose uptake (26).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612794	The collected samples (1x10ˆ5 cells) were separated by SDS-PAGE (SuperSep Ace, 5–20%; Wako) and transferred onto PVDF membranes (Immobilon®-P; Merck).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612794	Error bars show the mean ± SD; p-values were calculated by one-way ANOVA (F (2,27) = 672.4; p < 0.0001) followed by Tukey’s test.(F) Immunoprecipitation using anti-FLAG antibody in AID-based CENP-T conditional knockdown CENP-C/GFP-Dsn1 cells expressing 3xFLAG-CENP-T or 3xFLAG-CENP-T. Cells were cultured with IAA for 12...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Inverse probability of treatment weighting (IPTW) was used as another approach to further validate PSM analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inverse", "probability", "of", "treatment", ...
PMC11240052	The total protein was quantified using a bicinchoninic acid kit (Beyotime Institute of Biotechnology).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "total", "protein", "was", "quantified", "using"...
PMC11472639	RPMI-8226 cells (2 × 10) were labelled with the membrane permeable molecule, calcein acetoxymethyl ester (calcein-AM) (Invitrogen™, Thermo Fisher Scientific, Loughborough, UK).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10203589	In 2019, Zhang et al. explored the FGF mRNA profile in 10 GC cell lines by microarray analysis and found that the mRNA of FGF18 exhibited significantly high levels of expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5672695	Conclusions: Cord blood cotinine adversely affects birth outcomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conclusions", ":", "Cord", "blood", "cotinine", "adversely", "affects", "birth", "outcomes", "." ] } ...
PMC11532793	Baldoni et al. also showed that RTA dispersions can be divided out of the transcript read counts to obtain scaled counts with a more standard mean-variance relationship.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11783017	However, the increased PI-positive staining and decreased Calcein-AM-positive staining were observed for both Cis/Mn@Lipo-IL11+NH and Cis/Mn/NH@PGP groups (Fig. 3H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC9429973	We have previously shown that AUTO1, a fast off rate autologous CD19 CAR T cell therapy was highly active in ALL with a favorable safety profile and excellent persistence (Ghorashian et al Nat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9727330	Therefore, targeting amino acids such as Asp and amino acid synthetase like ASNS has been proved to be helpful pre-clinical therapy in various types of cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988555	The necrosis levels due to exposure to complexes 2 and 3 (7.8 and 6.1%, respectively) are statistically significantly higher when compared to the control DMSO (Figures 8 and S10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Further analyses will confirm the role of these pathways in maintaining ROS low LSCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "analyses", "will", "confirm", "the", "role", "of", "t...
PMC11496728	Three wells of each cell were expanded to a six-well plate suspension to detect the transient expression results, and three wells of each cell were screened with a DMEM/F12 complete medium containing rice to obtain a stable cell pool.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11407042	Discard trypsin and add 5 mL pre-warmed FBS-containing DMEM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Discard", "trypsin", "and", "add", "5", "mL", "pre-warmed", "FBS-containing", "DMEM", "." ] } ]
PMC11320834	Additionally, olaparib and durvalumab co-treatment show notable clinical activity in patients with germline BRCA1/2-mutated PSROC .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "olaparib", "and", "durvalumab", "...
PMC11752767	D Chimeric antigen receptors (CARs)-Natural Killer (NK) cells therapy Common approaches of adoptive cell therapy for advanced melanoma A Tumor-infiltrating cell therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	The validation cohort confirmed that patients with higher pretreatment ctDNA levels had inferior PFS (Figure 1B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "validation", "cohort", "confirmed", ...
PMC10932641	The noninvasive cells on the membrane were wiped clean with cotton swabs, and the membrane was washed twice with PBS, fixed with 4% formaldehyde, and stained with 0.1% crystal violet.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	During the brief clinical hold patients were maintained on their cytoreductive regimens and had TP for HCT >45%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "During", "the", "brief", ...
PMC8143558	Saponins that were extracted from Solanum trilobatum L. were tested for their antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8414691	As shown in Fig. 2A, SRCAP immunofluorescence clearly decorated the isolated midbodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "shown", "in", "Fig.", "2A", ",", "SRCAP", "immunofluorescence", ...
PMC9587866	In case of 1,7-Dihydroxy-3-methylanthracene-9.10-dione, it can also cause cardiac failure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "case", "of", "1,7-Dihydroxy-3-methylanthracene-9.10-dione", ",", "it", "can", "also", ...
PMC11594588	The inefficiency of the above process triggers significant ROS production in order to avoid mitochondrial damage by significant amounts of free electrons.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ineff...
PMC11739696	These findings align with previous studies that demonstrated strong cytotoxic effects of Co3O4NPs against other human cancer cells, including hepatocellular carcinoma Hep-G2 cells, CT26 colorectal cancer cells and mouse colon adenocarcinoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLin...
PMC11473843	Previous evidence suggested that DNA damage induced by ionizing radiation triggers ERK5 upregulation, which protect cells from DNA damage-induced cell death by enhancing the DNA damage response (Jiang et al, 2019).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746942	The next day, the antibody-bound protein complex was captured using protein A or G beads.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "next", "day", ",", "the", "antibody-bound", ...
PMC11377827	The rapid changes in HIF-1α levels on chromatin suggest that the USP43/14-3-3 interaction with HIF may help with the initial nuclear localisation of the transcription factor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	All CLL cell lines analyzed showed a lower basal expression of NFE2L2, HMOX1, and GPX4 antioxidant genes than typical iron-resistant cell lines, such as prostate cancer PC-3 cells, suggesting that differences in antioxidant gene expression levels may mediate iron response and that this association is worth to be explor...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9599726	Although all experiments with VP were sheltered from ambient light to minimize possible photoactivation, we also tested CA3, a compound with a chemical structure distinct from VP, recently coined as a YAP inhibitor .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: the median follow-up time of HLA matched transplantation and mismatched transplantation were 24 months and 21 months, respectively (P = 0.333).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10380508	A hypothesis test was performed using the Mantel–Cox test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "hypothesis", "test", "was", "performed", "using", "the", "Mantel", "–", "Cox", ...
PMC10253553	This could explain why reducing RICTOR, but not inhibition of mTOR reduced the levels of total NDRG1 protein (Figure 2 and Figure 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11783017	The liposomes encapsulated with cisplatin-loaded mesoporous MnO2 target tumor cells through surface-modified IL11Rα.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "liposomes", "encapsulated", "with", "cisplatin-loaded", "mesoporous", "MnO...
PMC11388384	Weighted average diffusion rate of SHH (black trace and axis) was not correlated to gradient lengthscale (red trace and axis) across a range of SCUBE1 concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585994	The procedure for constructing the T-ALL PDX model is summarized as follows: Male B-NDG mice, aged 6 to 8 weeks, received total body irradiation at a dose of 1 Gy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7582629	Popp et al. have recently proposed a high-throughput screening RS (HTS-RS) platform based on the combination of an automated bright-field recognition routine able to select the single-cell focal plane with Raman spectroscopy for rapid and label-free macromolecular fingerprinting of tens of thousands of eukaryotic cells...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10975211	The ATCUN motif influenced the nuclease activity and made these peptide conjugates more active and stable than the parental AMP .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ATCUN", "motif", ...
PMC11402217	Normalized expression of E-cadherin and N-cadherin protein expression in western blotting. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Normalized", "expression", "of", "E-cadherin", "and", "N-cadherin", "protein", "expres...
PMC8357004	The Caco-2 cells were cultured and treated with 5-Aza-CdR and TSA (alone and combined).	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Caco-2", "cells", "were", "cultured", ...
PMC10743717	More importantly, it was revealed that the subcellular fractionation data for the demonstration of the association of ERAB/HADII with the endoplasmic reticulum were secured by the use of an unreasonable modification of the traditional procedure invented by the Nobel laureate Prof. Christian de Duve (see SM1 and SM2a of...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Both the 65-year-old mother with complaints of headaches, and her 39-year-old son with a medical history of retinal vein occlusion were heterozygous for this variant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11739484	The cell proliferation assay showed significantly lower growth rates in si-MMP7-A375 cells compared to control cells, underscoring MMP7’s role in promoting melanoma cell proliferation (Fig. 10D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365427	All data were presented as means ± standard error of mean (SEM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "data", "were", "presented", "as", "means", "±", "standard...

PMC11024707

In autism, there often is a general speech delay.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "autism", ",", "there", "often", "is", "a", "general", "speech", "delay", "." ] ...

PMC11754432

Subsequently, the secretion of cytokines was analysed by cytometric bead array (Fig. 2F–J).

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PMC11532793

While both edgeR and Swish accept as input RNA-seq quantification from both kallisto and Salmon, with either bootstrap or Gibbs sampling, sleuth accepts RNA-seq quantification output only from kallisto.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11335267

This study highlights the crucial role for Alx3 in governing food intake, energy homeostasis, and metabolic nutrient partitioning, thereby influencing body mass composition.

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PMC9878278

ZIKV titers in the supernatants from siCtrl and double knock-down (DKD) with siMDA5 and siRIG-I cells were determined by plaque assay at 48 hpi and expressed as PFU/mL supernatant. (

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PMC7759933

In our study, the proliferation of cells and their distribution within the cell cycle of spheroids with the initial density of 3000 and 6000 cells/spheroid were determined by flow cytometry over the time of cultivation, with simultaneous detection of the fluorescent signals of FITC corresponding to the proliferation ma...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11786767

After washing with PBS, AlexaFluor-555-conjugated tyramide was diluted (1:50) in amplification diluent and applied to the cells for 15 min.

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PMC11803149

In some experiments, CD8 T cells were activated with Dynabeads Mouse T-activator CD3/CD28 beads (Gibco, 11456D).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "some", "experiments", ...

PMC11615743

Comparatively, the control cell lines with single‐positive or dual‐negative recognition patterns for Sgc8 and TC01 (such as human Burkitt's lymphoma cells, Ramos; human acute T leukemia cells, Jurkat; and human erythromyeloblastoid leukemia cells, K562 ) exhibited minimal fluorescence enhancement, with a signal gain lo...

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PMC11762280

Primary antibodies against phospho-MLKL (Ser358, #ab187091 for human), GSDMD (#ab209845 for mouse), NLRP3 (#ab263899), MPO (#ab208670), MMP-9 (#ab283575), CD4 (#ab183685), and CD8 (#ab217344) were from Abcam (Cambridge, MA, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10470467

Finally, to evaluate the signature’s generalization ability, we used the other independent dataset, GSE63157, as validation data and followed the same procedure as described above.

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PMC9429973

Of interest, when Ddx41-derived BM cells were co-transplanted with Ddx41-derived BM cells, some of the recipient mice showed impaired hematopoiesis, suggesting the presence of a non-cell autonomous effect of Ddx41 cells on Ddx41 cells.

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PMC10440586

The GSEA plot in the hypoxia genes set of the TCGA dataset. (

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PMC10669966

This final IST reference list contained a total of 2754 genes and was used as an exclusion list, to eliminate non-LPS-specific genes from the LPS-subtype differential-gene-expression analyses.

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PMC11529598

D. Cell cycle analysis was performed on miR-3154 sponge transfected cells and control cells using flow cytometry.

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PMC11727145

However, in our experiments, the K14 protein was not present.

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PMC11695546

Earlier every test, the stock solutions were diluted by a 20 mM sodium phosphate buffer solution (pH 7.6) to a range of concentrations.

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PMC10810426

Knockdown efficacy is shown in the middle panel and effects on cell viability in the bottom panel.

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PMC9429973

Summary/Conclusion: This study draws attention to the level of anxiety in patients with hematological malignancies of the COVID-19 pandemic.

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PMC11743414

Previous reports have shown that FHL1 acts through various mechanisms, including the inhibition of tumor cell growth through the tumor growth factor-β-like signaling pathway and negative regulation of the G2/M transition mitotic cell cycle .

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PMC7812570

After incubation for 24 h, the transduced cells were extensively washed and cultured in complete DMEM.

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PMC9429973

Type A inserts were found in 48 out of 78 cases (61.5%), type B - in 2 out of 78 (4.5%), and type D - 15.4% (12 out of 78).

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PMC9848491

IC50 of JNK inhibitor VIII high and low risk groups. (

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PMC11206251

Compounds with anti-HCC effects include glabridin , baohuoside I , kaempferol , isorhamnetin , morin hydrate , kaempferitrin , genistein , pectolinarigenin , quercetin , luteolin , tangeretin , calycosin , and hyperin .

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PMC11395280

Under homeostatic conditions, CCR7 is sulfonated on tyrosine residues that promote interaction with CCL19 .

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PMC11509309

After 24 h, the medium was replaced with a culture medium containing 0.45 µg/mL tunicamycin (Tm, Sigma Aldrich, Saint-Louis, MO, USA, #SML1287) and concentrations of molecules indicated on each figure or DMSO as a negative control.

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PMC8633974

To ensure TatDE cleavage is restricted to HIV-1 proviral DNA, we investigated the potential for aberrant indels at off-target loci in the human genome.

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PMC9841531

A Knoevenagel condensation with methyl cyanoacetate revealed 2-(3-(2-cyano-3-methoxy-3-oxoprop-1-en-1-yl)-1H-indol-1-yl) acetic acid (16).

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PMC11380454

We recently described the unique ability of AS101 to regulate cellular VLA-4 activity via redox modulation of vicinal thiols on the exofacial domain of the VLA-4 integrin 29.

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PMC6133382

The reaction was quenched by adding water (1 mL), and the permethylated N-glycans were extracted by organic phase separation using dichloromethane (2 mL).

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PMC11740907

The current research’s findings corroborated those of a previous study that found that hydrolysates of fenugreek protein inhibited the proliferation of colorectal cancer cells.

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PMC11089031

C IHC staining of ccRCC cancer tissue (showing the results of half of the samples, n = 29; total number = 58).

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PMC11723947

1Treg are less effective in regulating allogeneic responses mediated by HP1α-deficient T cells than by their wild-type counterparts.

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PMC11185260

When siRNA was encapsulated in scL nanocomplex, the serum stability of siRNA was significantly improved that intact scL-siRNA is clearly present in circulation for at least 24h after an intravenous administration in mice, while free siRNA without delivery system was undetectable at 3h in blood (unpublished data), sugge...

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PMC9429973

Proportion of patients treated with CIT tended to diminish with subsequent LOT, whereas the proportion treated with ibrutinib tended to increase.

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PMC9027909

Another study by the same team, which was performed in Caco-2 cell line, suggested that ST7 changed the permeability and tight junction localization, which that led to disruption of the intestinal barrier .

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PMC11721096

Therefore, it is of great significance to discover safe and effective tyrosinase inhibitors.

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PMC9019892

Effect of Nintedanib and Imatinib in GIST‐882 mouse xenograft models in vivo. (

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PMC10969097

Recently, four new characteristics have been proposed as significant additions to our understanding of cancer and its microenvironment.

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PMC9429973

Evaluable pts included 26 PON-pretreated and 19 PON-naive pts; 34.6% and 68.4%, respectively, achieved MMR by the cutoff date (Table).

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PMC7553912

Immunofluorescence staining for OSM (a) or OSMRβ (d, g, j, m) is shown in the left line (red).

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PMC10595704

Their capability to cross physiological barriers was assessed by Parallel Artificial Membrane Permeability Assay (PAMPA) and Caco-2 cell monolayer.

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PMC9429973

Our previous analysis of whole exome germline data from 895 MM patients in the MMRF CoMMpass dataset showed ~8% of MM patients carry a PGV in a hereditary cancer gene (HCG), and identified shared characteristics among PGV carriers including younger age at diagnosis, higher likelihood of having family history of hematol...

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PMC11672617

Therefore, the synthesized ionic compounds and hybrid molecules based on lithocholic acid are more “soft” dissociators than, for example, the well-known and widely used CCCP.

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PMC11742047

A higher degree of lipid compound alteration following CBD administration was observed in the K-562 cell line.

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PMC10158546

ReN cells were seeded and cultured in complete growth medium for 2–3 days until they reached confluence.

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PMC11678130

Before the application of the staining protocol, the cells were fixed with 4% paraformaldehyde for 15 min at room temperature, permeabilized with 0.1% Triton-X for 15 min at room temperature, and treated with a 1% BSA solution in PBS for 45 min at room temperature.

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PMC11750165

Maintenance of neural progenitors requires Notch signaling in vertebrate development.

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PMC10976516

Of 21 patients with >6 months follow-up 7 had PFS ≥6 months (33.3%).NCT00998192Gong et al.SenecavirusSeneca Valley virus (NTX-010)NTX-010 after 4 cycles of platinum-based chemotherapyIISystemic i.v.

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PMC11612315

d Effects of intraplantar administration of exendin 9–39 (5 and 10 μg) and BCTC (0.5 μg) on CAP (1.6 μg)-induced acute licking time (mean ± S.E.M., n = 5).

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PMC9412887

Since ICB are inherent to T cells, lymphocytes and not cancer cells are the target cells of ICB.

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PMC11519583

It is well established that intercellular crosstalk between SCs and MPs plays a critical role in regulating skeletal muscle maintenance and regeneration .

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PMC10376064

Furthermore, drug repurposing to treat neurodegenerative diseases is highly encouraged by the European Medical Agency (EMA, Amsterdam, Nederlands) and the Federal Drug Agency (FDA, Silver Springs, MD, USA).

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PMC9325715

Generally, the appearance of the bands corresponding to more than one functional group in the same region is the main drawback of spectroscopy in the infrared range.

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PMC11665555

For stable Cas9-expressing cells, we used a lentivirus transfection method.

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PMC11684269

However, in type 2 diabetes (T2D) individuals, hyperglycemia impairs memory CD8 T cells by insulin-derived GLUT1 upregulation and enhanced glucose uptake (26).

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PMC11612794

The collected samples (1x10ˆ5 cells) were separated by SDS-PAGE (SuperSep Ace, 5–20%; Wako) and transferred onto PVDF membranes (Immobilon®-P; Merck).

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PMC11612794

Error bars show the mean ± SD; p-values were calculated by one-way ANOVA (F (2,27) = 672.4; p < 0.0001) followed by Tukey’s test.(F) Immunoprecipitation using anti-FLAG antibody in AID-based CENP-T conditional knockdown CENP-C/GFP-Dsn1 cells expressing 3xFLAG-CENP-T or 3xFLAG-CENP-T. Cells were cultured with IAA for 12...

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PMC9429973

Inverse probability of treatment weighting (IPTW) was used as another approach to further validate PSM analysis.

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PMC11240052

The total protein was quantified using a bicinchoninic acid kit (Beyotime Institute of Biotechnology).

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PMC11472639

RPMI-8226 cells (2 × 10) were labelled with the membrane permeable molecule, calcein acetoxymethyl ester (calcein-AM) (Invitrogen™, Thermo Fisher Scientific, Loughborough, UK).

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PMC10203589

In 2019, Zhang et al. explored the FGF mRNA profile in 10 GC cell lines by microarray analysis and found that the mRNA of FGF18 exhibited significantly high levels of expression.

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PMC5672695

Conclusions: Cord blood cotinine adversely affects birth outcomes.

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PMC11532793

Baldoni et al. also showed that RTA dispersions can be divided out of the transcript read counts to obtain scaled counts with a more standard mean-variance relationship.

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PMC11783017

However, the increased PI-positive staining and decreased Calcein-AM-positive staining were observed for both Cis/Mn@Lipo-IL11+NH and Cis/Mn/NH@PGP groups (Fig. 3H).

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PMC9429973

We have previously shown that AUTO1, a fast off rate autologous CD19 CAR T cell therapy was highly active in ALL with a favorable safety profile and excellent persistence (Ghorashian et al Nat.

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PMC9727330

Therefore, targeting amino acids such as Asp and amino acid synthetase like ASNS has been proved to be helpful pre-clinical therapy in various types of cancer.

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PMC10988555

The necrosis levels due to exposure to complexes 2 and 3 (7.8 and 6.1%, respectively) are statistically significantly higher when compared to the control DMSO (Figures 8 and S10).

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PMC9429973

Further analyses will confirm the role of these pathways in maintaining ROS low LSCs.

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PMC11496728

Three wells of each cell were expanded to a six-well plate suspension to detect the transient expression results, and three wells of each cell were screened with a DMEM/F12 complete medium containing rice to obtain a stable cell pool.

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PMC11407042

Discard trypsin and add 5 mL pre-warmed FBS-containing DMEM.

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PMC11320834

Additionally, olaparib and durvalumab co-treatment show notable clinical activity in patients with germline BRCA1/2-mutated PSROC .

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PMC11752767

D Chimeric antigen receptors (CARs)-Natural Killer (NK) cells therapy Common approaches of adoptive cell therapy for advanced melanoma A Tumor-infiltrating cell therapy.

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PMC9429973

The validation cohort confirmed that patients with higher pretreatment ctDNA levels had inferior PFS (Figure 1B).

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PMC10932641

The noninvasive cells on the membrane were wiped clean with cotton swabs, and the membrane was washed twice with PBS, fixed with 4% formaldehyde, and stained with 0.1% crystal violet.

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PMC9429973

During the brief clinical hold patients were maintained on their cytoreductive regimens and had TP for HCT >45%.

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PMC8143558

Saponins that were extracted from Solanum trilobatum L. were tested for their antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae.

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PMC8414691

As shown in Fig. 2A, SRCAP immunofluorescence clearly decorated the isolated midbodies.

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PMC9587866

In case of 1,7-Dihydroxy-3-methylanthracene-9.10-dione, it can also cause cardiac failure.

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PMC11594588

The inefficiency of the above process triggers significant ROS production in order to avoid mitochondrial damage by significant amounts of free electrons.

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PMC11739696

These findings align with previous studies that demonstrated strong cytotoxic effects of Co3O4NPs against other human cancer cells, including hepatocellular carcinoma Hep-G2 cells, CT26 colorectal cancer cells and mouse colon adenocarcinoma cells.

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PMC11473843

Previous evidence suggested that DNA damage induced by ionizing radiation triggers ERK5 upregulation, which protect cells from DNA damage-induced cell death by enhancing the DNA damage response (Jiang et al, 2019).

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PMC11746942

The next day, the antibody-bound protein complex was captured using protein A or G beads.

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PMC11377827

The rapid changes in HIF-1α levels on chromatin suggest that the USP43/14-3-3 interaction with HIF may help with the initial nuclear localisation of the transcription factor.

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PMC9429973

All CLL cell lines analyzed showed a lower basal expression of NFE2L2, HMOX1, and GPX4 antioxidant genes than typical iron-resistant cell lines, such as prostate cancer PC-3 cells, suggesting that differences in antioxidant gene expression levels may mediate iron response and that this association is worth to be explor...

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PMC9599726

Although all experiments with VP were sheltered from ambient light to minimize possible photoactivation, we also tested CA3, a compound with a chemical structure distinct from VP, recently coined as a YAP inhibitor .

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PMC9429973

Results: the median follow-up time of HLA matched transplantation and mismatched transplantation were 24 months and 21 months, respectively (P = 0.333).

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PMC10380508

A hypothesis test was performed using the Mantel–Cox test.

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PMC10253553

This could explain why reducing RICTOR, but not inhibition of mTOR reduced the levels of total NDRG1 protein (Figure 2 and Figure 3).

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PMC11783017

The liposomes encapsulated with cisplatin-loaded mesoporous MnO2 target tumor cells through surface-modified IL11Rα.

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PMC11388384

Weighted average diffusion rate of SHH (black trace and axis) was not correlated to gradient lengthscale (red trace and axis) across a range of SCUBE1 concentrations.

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PMC11585994

The procedure for constructing the T-ALL PDX model is summarized as follows: Male B-NDG mice, aged 6 to 8 weeks, received total body irradiation at a dose of 1 Gy.

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PMC7582629

Popp et al. have recently proposed a high-throughput screening RS (HTS-RS) platform based on the combination of an automated bright-field recognition routine able to select the single-cell focal plane with Raman spectroscopy for rapid and label-free macromolecular fingerprinting of tens of thousands of eukaryotic cells...

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PMC10975211

The ATCUN motif influenced the nuclease activity and made these peptide conjugates more active and stable than the parental AMP .

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PMC11402217

Normalized expression of E-cadherin and N-cadherin protein expression in western blotting. (

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PMC8357004

The Caco-2 cells were cultured and treated with 5-Aza-CdR and TSA (alone and combined).

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PMC10743717

More importantly, it was revealed that the subcellular fractionation data for the demonstration of the association of ERAB/HADII with the endoplasmic reticulum were secured by the use of an unreasonable modification of the traditional procedure invented by the Nobel laureate Prof. Christian de Duve (see SM1 and SM2a of...

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PMC9429973

Both the 65-year-old mother with complaints of headaches, and her 39-year-old son with a medical history of retinal vein occlusion were heterozygous for this variant.

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PMC11739484

The cell proliferation assay showed significantly lower growth rates in si-MMP7-A375 cells compared to control cells, underscoring MMP7’s role in promoting melanoma cell proliferation (Fig. 10D).

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PMC11365427

All data were presented as means ± standard error of mean (SEM).

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