OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9429973	Among them, mRNAs of the WT1, HGMA2, EVI1, BAALC, and PRAME genes are most frequently mentioned, but previous publications do not discuss the possible diagnostic value of individual combinations of activity of these genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	He underwent a course of therapy, including anticoagulants and IL-6 inhibitors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "He", "underwent", "a", "course", "of", "therapy", ",", "including", "anticoagula...
PMC9105697	The patient continued with routine follow-ups over the next three years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "patient", "continued", "with", "routine", "follow-ups", "over", "the", "next", ...
PMC11583010	Free exatecan also reached its maximum between 6 and 24 hours inside the tumor, and we observed a delay between the maximum concentration and the maximum PD effect of exatecan, as measured by the percentage of phosphorylated histone 2AX which peaked between 24 and 96 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11743414	D The mRNA expression level of FHL1 was detected by qRT-PCR A Effect of FHL1 on the percentage of apoptosis of HL60 cell lines under Ara-C 500 nM and DNR 2 nM treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC11678448	This finding is generally consistent with the anticipated fragment size.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "finding", "is", "generally", "consistent", "with", "the", "anticipated", "fragment", "si...
PMC6892818	As positive controls, lysates from HCT116 cells that were treated with control (‘C’) or treated with mCD40L (‘mL’) for 6 h were included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11306331	p > 0.05; : p < 0.05, : p < 0.01, **: p < 0.001 G, H Quantification of dissolution efficiency from microscopy data by calculating the change in the coefficient of variation and enrichment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	Using this workflow, we showed the feasibility of phosphoproteomics combined with INKA analysis of patient samples from a clinical molecular profiling study with kinase inhibitors (Labots et al, in preparation), showing a reduced INKA score of EGFR upon erlotinib treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11633763	In the study, the use of human tissue was clearly approved by the Ethics Committee of the Second Affiliated Hospital of Nanchang University.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11155445	The IC50 values for the synthesized complexes were in the range from 2.07 μM to 21.25 μM against MCF-7 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "IC50", "values", ...
PMC8526701	Previous studies showed that administration of imatinib alone can lead to mild DNA damage .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previous", "studies", "showed", "that", "administration", "of", "imati...
PMC9429973	Sixty-four percent of patients completed all doses of obinotuzumab, 50% requiered a dose reduction of acalabrutinib to 100 mg per day due to adverse events (AE).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4816271	A representative flow-cytometric analysis of this staining is shown in Fig 2B.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "representative", "flow-cytometric", "analysis", "of", "this", "staining", "is", ...
PMC7917457	With this platform, OAds can be quickly coated with a patient’s unique set of tumor-specific antigens, a prerequisite for personalized cancer immunotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11365983	The data presented also provide a clinical explanation for the pleiotropic phenotypes associated with FOXC1 mutation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "presented", "also", "provide", "a", ...
PMC11545737	SpvC shares 63% amino acid identity with S. flexneri OspF and has the same phosphothreonine lyase activity on MAPK .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SpvC", "shares", "63", ...
PMC9429973	Booster dose and antiviral treatments did non influence neither OS, nor time to a negative viral test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Booster", "dose", "and", "antiviral", ...
PMC11095939	Right panel: quantification of Mecp2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Right", "panel", ":", "quantification", "of", "Mecp2", "." ] } ]
PMC11795610	Afterward, cells were then incubated with Hank’s balanced salt solution (HBSS) containing 5 µM Fluo-4/AM for 30 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Afterward", ...
PMC9429973	Methods: Incident patients with ITP ≥18 years were identified in the nationwide Danish health registries during 1980-2016 by using the first registration of the designated codes 287.10 (ICD-8) or D.69.3 (ICD-10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670954	TEER was measured 24 h after intervention using an ERS-2 epithelial voltohmmeter (Millicell-ER-2, Millipore MERS00002, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TEER", "was", "measured", ...
PMC10421378	The results (shown in Figure 9) show that the viability of stored preparations (measured in cfu/g) was highest for the samples stored at −20 °C, as those were the only samples to have a recorded viability of over 10 cfu/g for the whole 12 months.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988555	The WB data allow a more precise quantification of the BAX and BCL-2 levels, which are involved in the control of mitochondrial membrane permeability (Figure 10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11794568	EDU cell proliferation assay was used to assess the proliferative capacity after the addition of rotenone to CRIP1-silenced cutaneous melanoma cells (scale bar is 50 μm). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11240448	However, if the choice of analytes to measure is supervised, even with 10 analytes the flawless classification of cell states can be achieved.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC6133382	For cell growth studies, CHO cells were grown in BalnCD CHO Growth A Medium (Irving Scientific, Santa Ana, CA, US).	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628904	This represents a nearly 60% increase in burn depth over 6 days and is indicative of burn wound conversion (Figure 5D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7294030	Cells were seeded in 6-well plate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "seeded", "in", "6-well", "plate", "." ] } ]
PMC11487720	By confocal microscopy, lamin B1 was shown to localize in the nuclear membrane and α-tubulin in the cytoplasm of untreated L929S cells (Fig. 5C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC11607764	In this study, we demonstrated gene expression, survival time, genetic alteration, immune infiltration, the related genes and miRNAs prediction, GO and KEGG pathway enrichment analysis of PTBP1 in pan-cancer by using different databases (including TCGA, CPTAC and GEO databases).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739504	Counted cell numbers were as follows: controls with serum starvation for 6 h, n = 685; 12 h, n = 665; 24 h, n = 589.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742047	Statistical analysis was carried out by univariate (UVA, Matlab R2022a) and multivariate analysis (MVA, SIMCA 17).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", ...
PMC11352746	The two types of microscopy used in IncuCyte systems are phase-contrast and fluorescent microscopy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "two", "types", "of", "microscopy", "used", "in", "IncuCyt...
PMC11697189	The findings revealed that 34 immune checkpoint genes were differently expressed in different groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "findings", "revealed", "that", "34", "immune", "checkpoint", ...
PMC11352311	Consequently, we investigated esculin’s impact on glucose metabolism.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", "we", "investigated", "esculin", "’s", "impact", "on", "glucose", "metabolis...
PMC11502962	These pieces were digested with collagenase IV for 15 min at 37°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "pieces", "were", "digested", "with", "collagenase", "IV", ...
PMC11683240	Subsequently, the cells were washed, fixed, permeabilized, and quenching was performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "the", "cells", "were", "washed", ",", ...
PMC11307990	Finally, the cells were incubated with DAPI working solution at room temperature in the dark for 5 min and then were washed with 1× PBS three times and imaged by laser confocal fluorescence microscopy (TCS SP8, Leica).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9596868	Additionally, we observed that homology repair pathway genes are significantly downregulated upon combined treatment with MST-312 and quercetin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "we", "observ...
PMC9429973	Aims: To describe the clinical characteristics of secondary MNs in patients with IBDs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "describe", "the", "clinical", "characteristics", ...
PMC11534035	When the treatment concentration was increased to 2.5 μM, the average colony size was found to be 31.40±0.9753 px (vs. control; p<0.0001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC7759933	Time-dependent elevation of UGT1A1 expression in HepG2 spheroids was already previously reported by Ramaiahgari et al. (2014) and Štampar et al. (2019) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Primary endpoints were efficacy (proportion of pts with complete response [CR; Hgb ≥12 g/dL] or partial response [PR; Hgb 10–12 g/dL or ≥2 g/dL increase from baseline, inclusive of CRs] at any visit from Wk 6–12) and safety (treatment-emergent adverse events [TEAEs]).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4005030	The addition of roselle calyx extract or protocatechuic acid did not affect cooking loss, pH value, sensory attributes and content of fat, protein, and moisture of beef samples during storage at 4°C for 15 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697189	N6-Methyladenosine-Modified HSPA7 is correlated with the tumor microenvironment of glioblastoma and could predict the response to immune checkpoint therapy, which is considered as a prognostic risk factor for glioblastoma patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8903741	C SDS-PAGE analysis of #6 antibody after (+) or before (–) protein reducing through 100 mM DTT and heating.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11391695	Additionally, the pcDNA/PEI/NPs@M treatment group exhibited increased levels of ACYP2 protein and decreased levels of p-ERK and TERT proteins, similarly, increased levels of ACYP2 mRNA and decreased levels of KCNN4 and TERT mRNA, as determined by qRT-PCR and western blot assays (Fig. S7A, B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9436459	0.7 μg/mL (5-FU)HCT-8n.a.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "0.7", "μg/mL", "(5-FU)HCT-8n.a", "." ] } ]
PMC10988555	Stability tests were also performed to evaluate complexes’ stability/solubility issues when incubated in a cell culture medium over time (Figure S9).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11092382	The above two studies employed distinct murine models of septic liver injury, providing ample evidence supporting the protective effect of sophocarpine against this injury through multiple mechanisms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730311	Created with BioRender.com.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Created", "with", "BioRender.com", "." ] } ]
PMC11754094	U2OS and K562 were transfected with the Neon transfection system (Invitrogen).	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "U2OS", "and", "K562", "were", "transfected", "with", "the", ...
PMC11547972	SFN, applied at 5 µM was also only marginally effective.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SFN", ",", "applied", "at", "5", "µM", "was", "also", "only", "marginally", "ef...
PMC10813895	Remarkably, a significant reduction in ELF5 expression was observed in 12.3% of the average-risk population, closely reflecting the BC incidence rate, which suggests the potential of the ELF5 clock to pinpoint high-risk individuals in a general population.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10936243	Percentage of basic resources available for post-OVH cats as reported by participants. “	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Percentage", "of", "basic", "resources", "available", "for", "post-OVH", "c...
PMC11279397	Viruses can give rise to a range of diseases, including COVID-19 , hepatitis B , AIDS , influenza , and others.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Viruses", "c...
PMC9429973	While mortality was 51(32.9%), 23(16.3%) and 5(9.3%), respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "mortality", "was", "51(32.9", "%", ")", ...
PMC8345486	The ring cleavage of 8-dioxane-[3,3′-chroma bis(1,2-dicarbollide)] (7) was shown by our group in previously published works ; however, its synthesis and characteristics are described for the first time herein (Scheme 2), inclusive of its molecular structure (Figure 13 with the description below).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10454535	Inhibition of thioredoxin has been shown to cause ROS-dependent apoptosis in MM cells and sensitizes MM cells to certain treatments including NF-ĸB inhibitors .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inhibit...
PMC11740907	This approach is crucial in the field of drug development as it allows for the identification of possible drug candidates, comprehension of binding processes, and assistance in the design of drugs based on their structure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680562	The distribution of particle size of CuO NPs Pectin, a natural polysaccharide, possesses exceptional biocompatibility, gel-forming capabilities, and mucoadhesive properties, guaranteeing therapeutic agents' sustained release and protracted retention at the applied site .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11371747	We next determined the gene expression levels of RFC and PCFT in the cell line panel indicated in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "next", "determined", ...
PMC11627133	First, EGFR was visualized on live A431 cells expressing H2B‐GFP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "First", ",", "EGFR", "was", "visualized", "on", "live", "A431", "cells", "ex...
PMC11422497	shRNA: short hairpin RNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "shRNA", ":", "short", "hairpin", "RNA", "." ] } ]
PMC11470999	The efficiency of forming brain metastasis can be improved through multiple rounds of selection in the brain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "efficiency", "of", "forming", "brain", ...
PMC11551844	Silica (2.0 g) was then added and the mixture was dried using a rotary vacuum evaporator (temperature was set at 40 °C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11143482	However, despite these aggressive interventions, patient outcomes have not significantly improved for decades.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "despite", "these", "aggressive", "interventions",...
PMC11345828	Data were collected at Life Sciences Collaborative Access Team (LS-CAT) 21-ID-G beamline, Advanced Photon Source (APS), Argonne National Laboratory.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11666785	This metric captures the randomness in super-resolved images.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "metric", "captures", "the", "randomness", "in", "super-resolved", "images", "." ] } ]
PMC11286266	These results were in line with our previous flow cytometry observations and suggested that CRT contributes to ER retention of ATF6α, either directly or indirectly. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10936243	another thing is staffing.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "another", "thing", "is", "staffing", "." ] } ]
PMC10502403	For cytokine inhibition studies, a t test was used if Levene’s test showed a value above the significance level; otherwise, Welch’s t test was used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11747885	The percentage of inhibition for each compound was calculated using the KNIME analytics platform.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "percentage", "of", "inhibition", "for", "each", "compound", ...
PMC10891340	Mitochondrial fusion involves the inner mitochondrial membrane (IMM) and the OMM, they can rearrange themselves to maintains the integrity of the organelle.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11055323	After which the magnet adsorbed to remove the supernatant; Wash twice with 200ul 1 × TWB buffer and once with 200ul EB buffer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Symptoms occurred on average three weeks after the second vaccine and have been outlined in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Symptoms", "occurred", "on", "average", "three", ...
PMC6102174	Sophora flavescens (Kushen) widely distributed throughout China is commonly used the treatment of skin diseases and gynecological diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sophora", "flavescens", "(",...
PMC7192625	This distinction can lead to interesting differences between these two types of genomic contacts, which are characterized by the presence of specific epigenomic features (25).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718274	of A-431 cells with diffused DNA%Apoptotic cells Untreated cells 0.00 µg/ml 936.67 ± 4.04 63.33 ± 4.04 6.33 ± 0.40 Doxorubicin 2 µg/ml 781.67 ± 7.64 218.33 ± 7.64 21.83 ± 0.76 Y 2 O 3 NPs 1/4 IC50 (7.47 µg/ml) 805.67 ± 5.03 194.33 ± 5.03 19.43 ± 0.50 1/2 IC50 (14.94 µg/ml) 642.33 ± 8.02 357.67 ± 8.03 35.77 ± 0.80 IC50 ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The efficacy of FEDR relative to NAV+RUX in patients with MF previously treated with RUX has not been evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "efficacy", "of", "FEDR", ...
PMC10907726	Data are represented as means ± SD; n = 3 per group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "represented", "as", "means", "±", "SD", ";", "n", ...
PMC7612475	Importantly, we also demonstrate that this aberrant DNA replication and repair can be exploited therapeutically to selectively target tumor cells carrying the SF3B1 mutation by using DNA-damaging agents, such as etoposide, or synthetic lethal small-molecule inhibitors, such as PARP inhibitors, which induce HR-dependent...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11332076	Immunocytochemical analysis demonstrated ERK phosphorylation in Cos-7 cells expressing myc-tagged F-iIR or F-iIGF1R (arrows).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunocytochemical", "analysis", "demonstrated", "ERK", ...
PMC9429973	In the same patient cohort herpesviruses replication in the history (before COVID-19), mainly during previous chemotherapy, was HSV1-2 33%, CMV 20%, EBV 33%, HHV6 67%, and overall 73%, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9622879	$$(t)=1if∑i=1NEi,Combuy(t)>∑i=1NEi,Comsell(t)0if∑i=1NEi,Combuy(t)<∑i=1NEi,Comsell(t)The meaning of formula (25) is that if the community buys energy from EP, the value of variable s(t) should be 1 (buying status) and if the community sells energy to EP, the value of variable s(t) should be 0 (selling status).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	During malignant transformation of T-cells, a clonal expansion of immature thymic cells is selected through the gradual accumulation of advantageous epigenetic changes and genetic mutations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11388384	Such a mechanism would permit the rapid exchange between alternative populations of SHH-Halo without changing the steady-state occupancy of each fraction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Such", "a", "mech...
PMC9429973	An effective desensitisation strategy is necessary as alternative donors for haploidentical HCT are often lacking.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "effective", "desensitisation", "strategy", "is", "necessary...
PMC6487404	The monolayers were incubated at 37 °C, placed in a shaker and shaken at 50 rpm during the transport process.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "monol...
PMC9596868	CI values vary for each combination, as presented in the CI versus FA plot using MS Excel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CI", "values", "vary", "for", "each", ...
PMC8567602	Here, loss of Smarcb1 in mesenchyme, including the Myf5Cre cell lineage with strong origination potential for synovial sarcoma (27, 28), drove tumorigenesis that instead resembled EpS by histologic features and transcriptome (Figs. 1 and 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11194678	After 24 h, cells were fixed with 4% paraformaldehyde and mounted on glass slides for imaging using a Leica TCS SP8 confocal microscope with a 64X oil-immersion lens with DAPI staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11406030	Briefly, total protein from the TOV-21G and SKOV3 cancer cell lines was extracted with 1× RIPA buffer (89900, Thermo Fisher Scientific), and 1× protease and phosphatase inhibitor cocktail (1861280, Thermo Fisher Scientific).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11185260	For Western blot analysis, the collected cells were lysed in cold radioimmunoprecipitation assay (RIPA) buffer containing protease inhibitors and 10μg of total cellular protein was separated on 4–12% Bis-Tris Midi gels (Thermo Fisher, Waltham, MA), transferred to a nitrocellulose membrane, and hybridized with antibodie...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11320084	The healing ability was weaker after 24 h in the si‐TNNT1 group versus the si‐NC group (Figure 2a,b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "heali...
PMC10571053	As shown in Figure 2A, OVCAR8 cells do not express P-gp, as determined with the P-gp-specific monoclonal antibody UIC-2, while NCI/ADR-RES cells express high levels of the transporter, as shown by increased staining with the UIC-2 antibody in NCI/ADR-RES cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "...
PMC10114490	High-throughput pharmaco-toxicological testing frequently relies on the use of established liver-derived cell lines, such as HepG2 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "High-throughput", "pharmaco-toxicological", ...
PMC11765988	Type 1 cytokines, such as interferon-gamma, are mainly involved in granulomatosis as potent activators of macrophages and mediators in their transformation into epithelioid histiocytes and multinucleated giant cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2118063	Deficiencies in AICDA in humans and mice result in markedly impaired CSR and SHM and, in contrast to mice deficient in BCL6, very large GC (54, 55).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Among them, mRNAs of the WT1, HGMA2, EVI1, BAALC, and PRAME genes are most frequently mentioned, but previous publications do not discuss the possible diagnostic value of individual combinations of activity of these genes.

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PMC9429973

He underwent a course of therapy, including anticoagulants and IL-6 inhibitors.

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PMC9105697

The patient continued with routine follow-ups over the next three years.

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PMC11583010

Free exatecan also reached its maximum between 6 and 24 hours inside the tumor, and we observed a delay between the maximum concentration and the maximum PD effect of exatecan, as measured by the percentage of phosphorylated histone 2AX which peaked between 24 and 96 hours.

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PMC11743414

D The mRNA expression level of FHL1 was detected by qRT-PCR A Effect of FHL1 on the percentage of apoptosis of HL60 cell lines under Ara-C 500 nM and DNR 2 nM treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...

PMC11678448

This finding is generally consistent with the anticipated fragment size.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "finding", "is", "generally", "consistent", "with", "the", "anticipated", "fragment", "si...

PMC6892818

As positive controls, lysates from HCT116 cells that were treated with control (‘C’) or treated with mCD40L (‘mL’) for 6 h were included.

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PMC11306331

p > 0.05; *: p < 0.05, **: p < 0.01, ***: p < 0.001 G, H Quantification of dissolution efficiency from microscopy data by calculating the change in the coefficient of variation and enrichment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6461034

Using this workflow, we showed the feasibility of phosphoproteomics combined with INKA analysis of patient samples from a clinical molecular profiling study with kinase inhibitors (Labots et al, in preparation), showing a reduced INKA score of EGFR upon erlotinib treatment.

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PMC11633763

In the study, the use of human tissue was clearly approved by the Ethics Committee of the Second Affiliated Hospital of Nanchang University.

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PMC11155445

The IC50 values for the synthesized complexes were in the range from 2.07 μM to 21.25 μM against MCF-7 cells.

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PMC8526701

Previous studies showed that administration of imatinib alone can lead to mild DNA damage .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previous", "studies", "showed", "that", "administration", "of", "imati...

PMC9429973

Sixty-four percent of patients completed all doses of obinotuzumab, 50% requiered a dose reduction of acalabrutinib to 100 mg per day due to adverse events (AE).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4816271

A representative flow-cytometric analysis of this staining is shown in Fig 2B.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "representative", "flow-cytometric", "analysis", "of", "this", "staining", "is", ...

PMC7917457

With this platform, OAds can be quickly coated with a patient’s unique set of tumor-specific antigens, a prerequisite for personalized cancer immunotherapy.

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PMC11365983

The data presented also provide a clinical explanation for the pleiotropic phenotypes associated with FOXC1 mutation.

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PMC11545737

SpvC shares 63% amino acid identity with S. flexneri OspF and has the same phosphothreonine lyase activity on MAPK .

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PMC9429973

Booster dose and antiviral treatments did non influence neither OS, nor time to a negative viral test.

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PMC11095939

Right panel: quantification of Mecp2.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Right", "panel", ":", "quantification", "of", "Mecp2", "." ] } ]

PMC11795610

Afterward, cells were then incubated with Hank’s balanced salt solution (HBSS) containing 5 µM Fluo-4/AM for 30 min.

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PMC9429973

Methods: Incident patients with ITP ≥18 years were identified in the nationwide Danish health registries during 1980-2016 by using the first registration of the designated codes 287.10 (ICD-8) or D.69.3 (ICD-10).

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PMC11670954

TEER was measured 24 h after intervention using an ERS-2 epithelial voltohmmeter (Millicell-ER-2, Millipore MERS00002, USA).

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PMC10421378

The results (shown in Figure 9) show that the viability of stored preparations (measured in cfu/g) was highest for the samples stored at −20 °C, as those were the only samples to have a recorded viability of over 10 cfu/g for the whole 12 months.

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PMC10988555

The WB data allow a more precise quantification of the BAX and BCL-2 levels, which are involved in the control of mitochondrial membrane permeability (Figure 10).

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PMC11794568

EDU cell proliferation assay was used to assess the proliferative capacity after the addition of rotenone to CRIP1-silenced cutaneous melanoma cells (scale bar is 50 μm). (

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PMC11240448

However, if the choice of analytes to measure is supervised, even with 10 analytes the flawless classification of cell states can be achieved.

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PMC6133382

For cell growth studies, CHO cells were grown in BalnCD CHO Growth A Medium (Irving Scientific, Santa Ana, CA, US).

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PMC11628904

This represents a nearly 60% increase in burn depth over 6 days and is indicative of burn wound conversion (Figure 5D).

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PMC7294030

Cells were seeded in 6-well plate.

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PMC11487720

By confocal microscopy, lamin B1 was shown to localize in the nuclear membrane and α-tubulin in the cytoplasm of untreated L929S cells (Fig. 5C).

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PMC11607764

In this study, we demonstrated gene expression, survival time, genetic alteration, immune infiltration, the related genes and miRNAs prediction, GO and KEGG pathway enrichment analysis of PTBP1 in pan-cancer by using different databases (including TCGA, CPTAC and GEO databases).

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PMC11739504

Counted cell numbers were as follows: controls with serum starvation for 6 h, n = 685; 12 h, n = 665; 24 h, n = 589.

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PMC11742047

Statistical analysis was carried out by univariate (UVA, Matlab R2022a) and multivariate analysis (MVA, SIMCA 17).

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PMC11352746

The two types of microscopy used in IncuCyte systems are phase-contrast and fluorescent microscopy.

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PMC11697189

The findings revealed that 34 immune checkpoint genes were differently expressed in different groups.

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PMC11352311

Consequently, we investigated esculin’s impact on glucose metabolism.

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PMC11502962

These pieces were digested with collagenase IV for 15 min at 37°C.

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PMC11683240

Subsequently, the cells were washed, fixed, permeabilized, and quenching was performed.

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PMC11307990

Finally, the cells were incubated with DAPI working solution at room temperature in the dark for 5 min and then were washed with 1× PBS three times and imaged by laser confocal fluorescence microscopy (TCS SP8, Leica).

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PMC9596868

Additionally, we observed that homology repair pathway genes are significantly downregulated upon combined treatment with MST-312 and quercetin.

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PMC9429973

Aims: To describe the clinical characteristics of secondary MNs in patients with IBDs.

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PMC11534035

When the treatment concentration was increased to 2.5 μM, the average colony size was found to be 31.40±0.9753 px (vs. control; p<0.0001).

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PMC7759933

Time-dependent elevation of UGT1A1 expression in HepG2 spheroids was already previously reported by Ramaiahgari et al. (2014) and Štampar et al. (2019) .

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PMC9429973

Primary endpoints were efficacy (proportion of pts with complete response [CR; Hgb ≥12 g/dL] or partial response [PR; Hgb 10–12 g/dL or ≥2 g/dL increase from baseline, inclusive of CRs] at any visit from Wk 6–12) and safety (treatment-emergent adverse events [TEAEs]).

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PMC4005030

The addition of roselle calyx extract or protocatechuic acid did not affect cooking loss, pH value, sensory attributes and content of fat, protein, and moisture of beef samples during storage at 4°C for 15 days.

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PMC11697189

N6-Methyladenosine-Modified HSPA7 is correlated with the tumor microenvironment of glioblastoma and could predict the response to immune checkpoint therapy, which is considered as a prognostic risk factor for glioblastoma patients.

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PMC8903741

C SDS-PAGE analysis of #6 antibody after (+) or before (–) protein reducing through 100 mM DTT and heating.

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PMC11391695

Additionally, the pcDNA/PEI/NPs@M treatment group exhibited increased levels of ACYP2 protein and decreased levels of p-ERK and TERT proteins, similarly, increased levels of ACYP2 mRNA and decreased levels of KCNN4 and TERT mRNA, as determined by qRT-PCR and western blot assays (Fig. S7A, B).

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PMC9436459

0.7 μg/mL (5-FU)HCT-8n.a.

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PMC10988555

Stability tests were also performed to evaluate complexes’ stability/solubility issues when incubated in a cell culture medium over time (Figure S9).

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PMC11092382

The above two studies employed distinct murine models of septic liver injury, providing ample evidence supporting the protective effect of sophocarpine against this injury through multiple mechanisms.

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PMC11730311

Created with BioRender.com.

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PMC11754094

U2OS and K562 were transfected with the Neon transfection system (Invitrogen).

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PMC11547972

SFN, applied at 5 µM was also only marginally effective.

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PMC10813895

Remarkably, a significant reduction in ELF5 expression was observed in 12.3% of the average-risk population, closely reflecting the BC incidence rate, which suggests the potential of the ELF5 clock to pinpoint high-risk individuals in a general population.

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PMC10936243

Percentage of basic resources available for post-OVH cats as reported by participants. “

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PMC11279397

Viruses can give rise to a range of diseases, including COVID-19 , hepatitis B , AIDS , influenza , and others.

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PMC9429973

While mortality was 51(32.9%), 23(16.3%) and 5(9.3%), respectively.

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PMC8345486

The ring cleavage of 8-dioxane-[3,3′-chroma bis(1,2-dicarbollide)] (7) was shown by our group in previously published works ; however, its synthesis and characteristics are described for the first time herein (Scheme 2), inclusive of its molecular structure (Figure 13 with the description below).

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PMC10454535

Inhibition of thioredoxin has been shown to cause ROS-dependent apoptosis in MM cells and sensitizes MM cells to certain treatments including NF-ĸB inhibitors .

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PMC11740907

This approach is crucial in the field of drug development as it allows for the identification of possible drug candidates, comprehension of binding processes, and assistance in the design of drugs based on their structure.

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PMC11680562

The distribution of particle size of CuO NPs Pectin, a natural polysaccharide, possesses exceptional biocompatibility, gel-forming capabilities, and mucoadhesive properties, guaranteeing therapeutic agents' sustained release and protracted retention at the applied site .

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PMC11371747

We next determined the gene expression levels of RFC and PCFT in the cell line panel indicated in Table 1.

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PMC11627133

First, EGFR was visualized on live A431 cells expressing H2B‐GFP.

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PMC11422497

shRNA: short hairpin RNA.

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PMC11470999

The efficiency of forming brain metastasis can be improved through multiple rounds of selection in the brain.

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PMC11551844

Silica (2.0 g) was then added and the mixture was dried using a rotary vacuum evaporator (temperature was set at 40 °C).

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PMC11143482

However, despite these aggressive interventions, patient outcomes have not significantly improved for decades.

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PMC11345828

Data were collected at Life Sciences Collaborative Access Team (LS-CAT) 21-ID-G beamline, Advanced Photon Source (APS), Argonne National Laboratory.

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PMC11666785

This metric captures the randomness in super-resolved images.

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PMC11286266

These results were in line with our previous flow cytometry observations and suggested that CRT contributes to ER retention of ATF6α, either directly or indirectly. (

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PMC10936243

another thing is staffing.

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PMC10502403

For cytokine inhibition studies, a t test was used if Levene’s test showed a value above the significance level; otherwise, Welch’s t test was used.

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PMC11747885

The percentage of inhibition for each compound was calculated using the KNIME analytics platform.

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PMC10891340

Mitochondrial fusion involves the inner mitochondrial membrane (IMM) and the OMM, they can rearrange themselves to maintains the integrity of the organelle.

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PMC11055323

After which the magnet adsorbed to remove the supernatant; Wash twice with 200ul 1 × TWB buffer and once with 200ul EB buffer.

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PMC9429973

Symptoms occurred on average three weeks after the second vaccine and have been outlined in Table 1.

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PMC6102174

Sophora flavescens (Kushen) widely distributed throughout China is commonly used the treatment of skin diseases and gynecological diseases.

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PMC7192625

This distinction can lead to interesting differences between these two types of genomic contacts, which are characterized by the presence of specific epigenomic features (25).

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PMC11718274

of A-431 cells with diffused DNA%Apoptotic cells Untreated cells 0.00 µg/ml 936.67 ± 4.04 63.33 ± 4.04 6.33 ± 0.40 Doxorubicin 2 µg/ml 781.67 ± 7.64 218.33 ± 7.64 21.83 ± 0.76 Y 2 O 3 NPs 1/4 IC50 (7.47 µg/ml) 805.67 ± 5.03 194.33 ± 5.03 19.43 ± 0.50 1/2 IC50 (14.94 µg/ml) 642.33 ± 8.02 357.67 ± 8.03 35.77 ± 0.80 IC50 ...

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PMC9429973

The efficacy of FEDR relative to NAV+RUX in patients with MF previously treated with RUX has not been evaluated.

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PMC10907726

Data are represented as means ± SD; n = 3 per group.

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PMC7612475

Importantly, we also demonstrate that this aberrant DNA replication and repair can be exploited therapeutically to selectively target tumor cells carrying the SF3B1 mutation by using DNA-damaging agents, such as etoposide, or synthetic lethal small-molecule inhibitors, such as PARP inhibitors, which induce HR-dependent...

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PMC11332076

Immunocytochemical analysis demonstrated ERK phosphorylation in Cos-7 cells expressing myc-tagged F-iIR or F-iIGF1R (arrows).

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PMC9429973

In the same patient cohort herpesviruses replication in the history (before COVID-19), mainly during previous chemotherapy, was HSV1-2 33%, CMV 20%, EBV 33%, HHV6 67%, and overall 73%, respectively.

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PMC9622879

$$(t)=1if∑i=1NEi,Combuy(t)>∑i=1NEi,Comsell(t)0if∑i=1NEi,Combuy(t)<∑i=1NEi,Comsell(t)The meaning of formula (25) is that if the community buys energy from EP, the value of variable s(t) should be 1 (buying status) and if the community sells energy to EP, the value of variable s(t) should be 0 (selling status).

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PMC9429973

During malignant transformation of T-cells, a clonal expansion of immature thymic cells is selected through the gradual accumulation of advantageous epigenetic changes and genetic mutations.

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PMC11388384

Such a mechanism would permit the rapid exchange between alternative populations of SHH-Halo without changing the steady-state occupancy of each fraction.

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PMC9429973

An effective desensitisation strategy is necessary as alternative donors for haploidentical HCT are often lacking.

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PMC6487404

The monolayers were incubated at 37 °C, placed in a shaker and shaken at 50 rpm during the transport process.

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PMC9596868

CI values vary for each combination, as presented in the CI versus FA plot using MS Excel.

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PMC8567602

Here, loss of Smarcb1 in mesenchyme, including the Myf5Cre cell lineage with strong origination potential for synovial sarcoma (27, 28), drove tumorigenesis that instead resembled EpS by histologic features and transcriptome (Figs. 1 and 2).

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PMC11194678

After 24 h, cells were fixed with 4% paraformaldehyde and mounted on glass slides for imaging using a Leica TCS SP8 confocal microscope with a 64X oil-immersion lens with DAPI staining.

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PMC11406030

Briefly, total protein from the TOV-21G and SKOV3 cancer cell lines was extracted with 1× RIPA buffer (89900, Thermo Fisher Scientific), and 1× protease and phosphatase inhibitor cocktail (1861280, Thermo Fisher Scientific).

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PMC11185260

For Western blot analysis, the collected cells were lysed in cold radioimmunoprecipitation assay (RIPA) buffer containing protease inhibitors and 10μg of total cellular protein was separated on 4–12% Bis-Tris Midi gels (Thermo Fisher, Waltham, MA), transferred to a nitrocellulose membrane, and hybridized with antibodie...

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PMC11320084

The healing ability was weaker after 24 h in the si‐TNNT1 group versus the si‐NC group (Figure 2a,b).

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PMC10571053

As shown in Figure 2A, OVCAR8 cells do not express P-gp, as determined with the P-gp-specific monoclonal antibody UIC-2, while NCI/ADR-RES cells express high levels of the transporter, as shown by increased staining with the UIC-2 antibody in NCI/ADR-RES cells.

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PMC10114490

High-throughput pharmaco-toxicological testing frequently relies on the use of established liver-derived cell lines, such as HepG2 cells.

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PMC11765988

Type 1 cytokines, such as interferon-gamma, are mainly involved in granulomatosis as potent activators of macrophages and mediators in their transformation into epithelioid histiocytes and multinucleated giant cells .

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PMC2118063

Deficiencies in AICDA in humans and mice result in markedly impaired CSR and SHM and, in contrast to mice deficient in BCL6, very large GC (54, 55).

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