Datasets:
OTAR3088
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BioData-CellLine_annotated

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PMC11588008
The measurement data were expressed as mean ± standard deviation (x ± s).
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PMC10723784
The MTT assay was carried out at 96 h from the initial addition of cannabinoids.
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PMC8345486
In contrast to 3, the cages of the chroma bis(dicarbollide) ion in 7 adopted a cisoid conformation close to an eclipsed arrangement.
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PMC5874706
Four α-cyclodextrins (α-CDs) were selected to encapsulate THN7 and all experiments indicated that the nanoencapsulation of this CK2 inhibitor in α-CDs was successful.
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PMC11271278
Metaphase arrest of NCIH2170 cells was performed by incubation with KaryoMAX (Gibco) at 0.1 µg/mL overnight.
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PMC9429973
In pts who required PLX, a median of 6.5×10 CD34/Kg (IQR 4.6-9.6) was collected.
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PMC11055510
The CircRNF144B/miR-342-3p/FBXL11 axis reduces autophagy and promotes ovarian cancer progression by increasing the ubiquitination of Beclin-1.
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PMC11767817
The DNA fragmentation enrichment factor (absorbance of treated cells/absorbance of untreated cells) was calculated according to the manufacturer’s instructions.
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PMC10705095
Our functional experiments revealed that when overexpressed, HBQ1 acts as an oncogene, enhancing cell proliferation, whereas HBQ1 knockdown inhibits it.
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PMC11593031
Table 1 summarizes the presence of prognostically important imbalances in human NBs compared to Neuro-2a.
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PMC11721587
The electroelution was performed using an Elutrap system (Cytiva) in a standard tris-glycine buffer containing 0.01% SDS at 4°C for 20 hours.
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PMC11791432
Alternatively, ANXA1 can induce the upregulation of programmed death-ligand 1 (PD-L1) expression on glioma cells , thereby facilitating the evasion of host immune surveillance and modulating the anti-tumor immune response.
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PMC6442998
However, imatinib-resistant GIST cell lines had not been studied, nor compared to imatinib-sensitive cells.
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PMC11472569
Another study revealed that chemoresistance can be transmitted from drug-resistant leukemia cells to their parental counterparts via EVs, likely due to the direct transfer of ABCC1.
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PMC9429973
Preemptive PLX in pts with ≥1 risk factors should be investigated to further reduce the risk of mobilization failure.
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PMC11461833
The translation of STXBP5 was evaluated with an anti-STXBP5 antibody, with normalized to -Actin expression. (
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PMC10938377
The substantial depot binding and lack of pronounced adduct formation at AU1 for the GAG conjugates, contrasting what is seen for Au–LANA, is likely attributable to a steric obstacle posed by the C-terminal Tyr residue of GAG, which binds in close proximity to AU1 (Fig. 2d).
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PMC10674574
The expended culture time and associated cell population drift may affect comparisons with historical permeability data.
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PMC11588085
It is consistent with the developmental role of XIST depletion during reprogramming and iPSC process that XIST loss in cancer cells leads to an enrichment of CSCs.
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PMC8875242
Statistical analysis of bidirectional transport across Caco-2 cells was performed using an ordinary one-way ANOVA with Dunnett’s post hoc multiple comparisons test.
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PMC11474209
Despite being strong, mtBER cannot repair all mtDNA damage.
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PMC9429973
In addition, clinical studies have reported significantly higher fatality rates and more severe complications in COVID-19 patients on immunosuppressive therapy (Lancet, 2020).
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PMC11489351
Pathway analysis showed that the top 500 gene ontology (GO) processes affected by changes in pHi were metabolism (16%) and signaling/signal transduction (16%), followed by differentiation, biosynthesis, and cell cycle (with less than 50 GO terms each).
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PMC10933092
Results were quantitatively analyzed using AlphaView software (ProteinSimple, United States).
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PMC11381192
LASSO regression analysis was performed to narrow the range of candidates, followed by multivariate Cox analysis to establish the final risk model.
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PMC11577421
Presumably, NP_BSA/NP_BSA+ interactions with surface GAGs increase the dwell time and promote the entrapment and retention of the particles near the cell surface, thus improving uptake efficiency.
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PMC9429973
It seems that they share common autoimmune pathways and further research of which is important for understanding pathophysiology behind these clinical entities and improving their treatment.
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PMC10936243
The current study provides an insight into the barriers faced by Malaysian veterinarians when it comes to the provision of good management for post-OVH cats in cages.
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PMC10114490
Statistical significance for fold induction was obtained by comparison with solvent-treated cells.*p < 0.05; **p < 0.01; ***p < 0.005 We evaluated intra-clonal variability of our cell pharmaco-toxicological system model by RNAseq of PD and PD diHLC-T. For this purpose, PD and PD iHDF-T cells were reprogrammed with Dox.
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PMC11679326
The main types of glycosylation are N- and O-glycosylation, and they are also the most studied and characterized, so we pay close attention to them in our review.
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PMC11665584
Across the tissues, vascular, neural, and muscle cells comprised 5%–15% of single cells captured for sequencing and 10%–40% of cells identified via Xenium (Figure 1C and Supplemental Figure 3D).
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PMC7229095
Host cell media require the additional components depending on the host cell line, HT is needed for dihydrofolate reductase (dhfr), deficient host cell lines (e.g. CHO-DG44, CHO-DUXB11), or glutamine for glutamine synthetase (GS), deficient host cell lines.
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PMC9100622
The highly variable frequency of EwS from one human population to another has long suggested a germline genetic susceptibility to this disease.
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PMC3813807
The dual-luciferase reporter plasmids were co-transfected with miRNA mimics (GenePharma) into HEK293 cells.
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PMC9429973
The dosing regimen for Lonca-R: Lonca at 0.15 mg/kg + rituximab at 375 mg/m every 3 weeks (Q3W) for 2 cycles and then Lonca at 0.075 mg/kg + rituximab at 375 mg/m Q3W for up to 6 cycles.
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PMC6450504
This decrease, however, was not statistically different and one explanation for the small difference in protein levels of siMDR1-treated animals could be related to protein recover.
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PMC9429973
Furthermore, the intracellular concentrations of the glutamate-dependent amino acids were more depleted under GLS1 inhibition in U266/MYC compared to U266/Ctrl.
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PMC11471176
Ten wells were arranged in a microplate, with one duplicate well designated as a blank control left empty.
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PMC11653533
Once more, it has been reported that, traditionally F. exasperata are also used by birthing experts to speed up the process of giving birth and by cows to speed up the process of placenta extraction following calf delivery (Bafor and Igbinuwen, 2009 Jun 22).
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PMC11718109
A Schematic flow of crude striatal brain homogenates embedded in agarose gel pooled from two mice.
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PMC11413393
n = 3 mice/group.
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PMC10419319
LDHA controls the conversion of pyruvate to lactate.
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PMC11726848
Electrophoresis was carried out in a fresh portion of an alkaline solution at 4 °C for 20 min at an electric field strength of 3.0 V/cm.
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PMC11770130
Food intake was measured based on the differences in the amount of diet that we provided in the morning on the first day and the amount of diet left in the morning of the second day.
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PMC9429973
Methods: We conducted a retrospective study with medical review of all patients diagnosed with multiple myeloma and treated with D-RVd at The National Center for Cancer Care and Research (NCCCR) in Qatar between January 2019 to December 2021.
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PMC11535726
Sexual morph: Undetermined.
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PMC9429973
All had a mutation in the HBB gene (β-thalassemia, severe β-thalassemia, and mild β-thalassemia).
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PMC11301095
However, the observed elevation in the total count of nucleated cells was inconsistent with the typical CSF profile associated with bacterial meningitis.
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PMC11011837
Unsupervised principal component analysis (PCA) on the polar metabolite matrix was performed (Figure 1).
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PMC8469018
In all assays, the cells were seeded into plates at concentration of 1.5 × 10 cells/mL. The cell cultures were treated with teriflunomide (A77 1726) (Selleckchem, München, Germany) in a wide range of concentrations (5–500 µM) or DMSO as vehicle in control cultures (maximal DMSO concentration < 0.5%).
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PMC10969097
The clinical trial NCT00779168, started in 2009, evaluated the use of Agaricus bisporus mushroom extract in patients with recurrent prostate cancer after local treatment.
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PMC11411131
First, the expression of other selenoproteins was studied.
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PMC11641532
Therefore, exploring new treatment strategies to improve patient prognosis is urgently needed.
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PMC10938336
Furthermore, the GO analysis was instrumental in elucidating the involvement of these genes in critical processes such as cancer cell proliferation and apoptosis.
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PMC11768927
Early-phase clinical trials have yielded evidence of a manageable safety profile and promising preliminary efficacy, although several recently initiated trials remain in progress and have yet to report final results.
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PMC8345486
Neutral red is a supravital dye that is taken up via active transport into live cells and is preferentially located in lysosomes .
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PMC11762280
The average optical densities of N-GSDMD, cleaved PARP, and p-MLKL positive staining were statistically analyzed (n = 12).
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PMC9780037
Upon cyt c binding, their fluorescence is quenched. (
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PMC11802929
We identified immunodominant epitopes against SARS-CoV-2 and common viruses across patients, confirming some previously reported epitopes while discovering additional ones (Supplementary Fig. 2b).
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PMC9424261
The transcriptome sequencing and analysis were conducted by OE Biotech Co., Ltd. (Shanghai, China).
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PMC6892818
Interestingly, ROS production occurred far sooner than apoptosis induction; another major ROS source is the Nox complex and studies in B cells have implicated the regulatory Nox-2 subunit p40phox in CD40 signalling.
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PMC11697703
Data are represented as mean ± SEM.
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PMC6889484
No NL4-3 replication was detected in 100% CEMSS/D128K cell lines, and near-wild-type kinetics (days 11–13) were observed in 100% CEMSS cells.
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PMC6114978
Treatment with 10 μM 5-azacytidine resulted in a modest increase in expression in 8–17% of the sarcoma cell lines.
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PMC7917457
Animals were treated 6, 8, and 20 days post-tumor implantation with PeptiCRAd Ad5/3-D24-OVA, PeptiCRAd VALO-mD901-OVA, or PBS as a mock-treated group.
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PMC11435360
Our results are in line with the finding from a previous study in which combination therapy with PAG and cisplatin reduced BC cell viability compared to cisplatin alone and enhanced cisplatin cytotoxicity by further reducing tumor size .
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PMC11766174
For this purpose, fixed cells were deposited on microscopy slides by the cytospin technique and stained with antibodies against CA by an automated stainer, followed by slide digitization.
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PMC10631132
Even though challenges and considerations still exist when it comes to clinical translation , the possibility for autologous usage could allow for the treatment of currently untreatable diseases [13–15].
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PMC8358006
And the pathways in cancer (hsa05200) were also enriched in the broadest H3K27me3 domains (FDR = 1.5 × 10).
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PMC10723784
In addition, both cannabinoids induced a higher percentage of apoptotic cells in carcinoma cells than in non‐carcinoma cells.
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PMC11640476
Results indicated that 3–4 h is the optimal incubation time when the cell concentration ranges from ~1 × 10 to ~1.6 × 10 cells/cm; 1.5–2 h for cell concertation between ~1.6 × 10 and ~7.5 × 10 cells/cm; 0.5–1 h for cell concertation exceeding ~7.5 × 10 cells/cm (Figure 2).
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PMC11519583
On the other hand, Wnt5a failed to affect binding of Wnt11 to Ror2, and Wnt11 inhibited binding of Wnt5a to Ror2 (Supplementary Fig. 10).
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PMC11473750
f Kaplan–Meier curves of Overall Survival probability of patients from the Kocak (n = 476) or SEQC neuroblastoma cohorts (n = 498) subgrouped above or below the upper-decile of RNF121 mRNA expression for the overall group.
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PMC7812570
To examine whether the expression of transgenes was truly linked with a GPI anchor, transduced TZM-bl cells were first treated with 5 U/ml PI-PLC (Invitrogen Life Technologies) in 0.5 ml of 1× PBS, rocked for 30 min at 4 °C, and then washed two times with FACS buffer to remove the remaining PI-PLC.
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PMC11306019
Growth curve of all groups.
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PMC9429973
Mass cytometry (CyTOF) experiments validated the cell cycle blockade after cPCMTD1-KD and identified an increase of H2AX phosphorylation.
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PMC11599565
Type II is involved in wound healing, tissue regeneration, and organ fibrosis.
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PMC11695623
Cell cycle checkpoint related gene CDK1 is the central tumor-promoting gene of LUAD.
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PMC9960565
Cisplatin binds to DNA first through monodentate adducts and then through bidentate adducts forming crosslinks with DNA .
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PMC11342785
E, schematic for studying synMAP circuit dynamics following nocodazole-induced microtubule depletion.
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PMC11754784
The set of rate constants acquired by fitting the time-dependent concentration changes of species is given in Supplementary Table 1.
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PMC9429973
The mPFS is 19.3m [15.1; 23.2] in L1, 12.6m [10.1; 17.5] in L2, 8.9m [10.1; 17.5] in L3 and 5.9m [4.5;7.4] in L4+.
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PMC11521786
Moreover, it would be interesting to evaluate whether simultaneous recognition of multiple epitopes of HER3 by these PAbs might enhance tumor inhibition with regard to specific MAbs, which could suggest a differentiation strategy from passive therapies, as reported by Bergado et al. in 2022 (25).
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PMC11337594
The cell culture medium was replaced with medium containing different concentrations of TER for a 48-hour incubation period.
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PMC9429973
Patterns of inflammatory markers, and long term follow up of recovered MPN pts with COVID-19 will be presented in the meeting.
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PMC11525293
Thalidomide prevents viral re-entry of SARS-CoV-2 by p63-dependent ACE2 downregulation.
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PMC9429973
A. Jiménez-Ubieto, M. Poza Santaella, A. Martin, Y. Heredia, S. Dorado, G. Figaredo, L. Rufian, A. Rodriguez, P. Sarandeses, T. Baumann, C. Grande, C. Bárcena, J. Martinez-Lopez, J.-M. Rosa, I. Rapado, R. Ayala, M. Gallardo, R. Sánchez, J. Carrillo, M. Calbacho, L. Parrilla, A. Juarez, M. Mollejo, L. F. Casado, C. Wang...
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PMC11365983
E14.5 Foxc1 embryos exhibited comparable reductions in forebrain meningeal pY754 Pdgfrα expression. (
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PMC11461833
Heatmaps were created with ggplot2 (version: 3.4.4, https://cran.r-project.org/web/packages/ggplot2).
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PMC7757104
Increasing concentrations of TMZ competed with calcein for P-gp, resulting in reduced efflux in the Adriamycin-resistant DC3F cells; however, various inhibitors of P-gp reversed TMZ resistance in two GBM cell lines by increasing the levels of active caspase-3, suggesting that P-gp may be a key regulator of TMZ resistan...
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PMC9429973
Diagnoses of MPN and non-MPN (other cancers excluding AML) cancers were based on International Classification of Diseases for Oncology, third edition (ICD-O-3) codes.
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PMC11434983
To solve this problem, along with the occasionally severe side effects observed, the introduction of new pharmacophores acting as dual-target inhibitors has been proposed .
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PMC11755467
--R2 <denatured_R2_read_file>: Path to R2 read file for denatured samples.
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PMC11583010
Both ADCs led to a similar antitumor effect compared with controls (Fig. 6A).
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PMC6835428
Germ cell tumors, accounting for just 5% of OCs, originate from germ cells and are almost exclusively found in juvenile populations.
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PMC11617590
In conclusion, SFN induces the inactivation of GSK‐3β by phosphorylation of Ser9.
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PMC9429973
To assess the landscape of transcriptional remodeling in BM after allo-SCT, we performed single-cell RNA sequencing (scRNAseq) of BM cells.
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PMC9844987
Expression levels were converted to tags per million (TPM), by normalizing the expression count of each tag cluster in each library as a fraction of its number of mapped CAGE reads, scaled by 10.
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PMC11087301
Thus leptin-correlated pathways affecting CSC and EMT may highlight novel targets as well as intervention approaches for reducing triple-negative breast cancer burden .
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PMC11335267
As a negative control, note the absence of Alx3 immunoreactivity in COS cells transfected with empty vector. (
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