OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9429973	iMCD patients were identified by CD-specific ICD-10 diagnosis code (D47.Z2), negative HHV-8 and HIV status, and diagnostic or laboratory claims for ≥2 minor criteria required to diagnose iMCD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8916024	An analysis of gut biomarker features of the adult and juvenile snails. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "analysis", "of", "gut", "biomarker", "features", "of", "the", "...
PMC9910796	In contrast, the subcellular localization of pp220 was drastically altered when co-expressed with pEP84R (Fig 5E, S7E and S7F Fig).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10297204	RFS was lower in the control group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RFS", "was", "lower", "in", "the", "control", "group", "." ] } ]
PMC11201989	The similarities between the primary cilium and immune synapse (interface formed between an antigen-presenting cell and the effector immune cell) have been increasingly recognized .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	These results make our PI-resistant models, an attractive preclinical model to test new therapeutic strategies to overcome PI resistance in MM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "res...
PMC11188874	Transfected cell lines were selected in complete medium with selection antibiotic.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transfected", "cell", "lines", "were", "selected", "in", "complete", "medium", "with", ...
PMC11750712	Adverse events over the first 28 days after CAR infusion were graded according to Common Terminology Criteria for Adverse Events (version 5.0).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11612315	Mechanical allodynia and thermal hyperalgesia were evaluated in separate experiments in a time-dependent manner.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mechanical", "allodynia", "and", "thermal", "hyperalgesia", "were", "e...
PMC6617630	JQ1, OTX, and I-BET at lower concentration (0.05 or 1μM) had a minimum inhibitory effect on proliferation of DHL and THL cells, although at higher concentrations such as 2.5 μM or 5 μM all of the three inhibitors significantly abrogated the proliferation of DHL/THL DLBCL cells and the inhibitory effect was similar to t...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "...
PMC9429973	Among them, 7 patients received PCIOD program and 14 patients received VTLP like program.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "them", ",", "7", "patients", "received", "PCIOD", ...
PMC11730311	Mice used for the pharmacokinetic study were housed in the AAALAC accredited animal facility at Gubra, Denmark.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "used", "for", "the", "pharmaco...
PMC11247842	Without a criterion to further prioritize these genes, we only kept the ones with biological support (see Additional file 1: Table S9) for downstream analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11243198	The higher efficacy of GANT61 analogs in reducing Gli1 expression compared to GANT61 at 96 h may be attributed, at least in part, to the reported low level of stability of GANT61 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10376064	First, we confirmed that DMF was stable in neutral drinking water (pH ~7.2) using spectroscopic measurements (Appendix A, Figure A1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8540611	Cellular uptake was critically small.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cellular", "uptake", "was", "critically", "small", "." ] } ]
PMC11760643	Furthermore, significantly greater P2X7 expression on CD4 effector memory cells compared with CD4 naive and central memory cells was shown previously, which was not observed here.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: In the acute leukemias group mortality was 25-82%, depending on the disease entity, disease status, age and intensity of the antineoplastic treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740508	Thus our PDX experimental result with TM00091, which bears the C61G mutation, may not be entirely irrelevant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", "our", "PDX", "...
PMC11656048	Therefore, 0.75 uM, 1.5 uM and 3 uM of shikonin concentration were selected for the following experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "0.75", "uM", ...
PMC9341513	Cycle threshold values were normalized by comparison with GAPDH expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cycle", "threshold", "values", "were", "normalized", "by", "comparison", "with", "GAPDH", "expre...
PMC11285179	Pearson or Spearman correlation was applied to analyze the relationship between the expression scores of two genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pearson", "or", "Spearman", "correlation", "was",...
PMC11656380	Using CCRF-CEM cells, we determined the mode of cell death induced by Tat-Ram13 and compared it to apoptosis induced by the DNA topoisomerase II inhibitor etoposide.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8481254	In previous studies, we confirmed that CA can effectively inhibit the expression of YAP, an important oncoprotein in HCC cells, and the proliferation of HCC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	K. Cwynarski, E. Tholouli, G. Iacoboni, T. Menne, D. Irvine, L. Wood, N. Balasubramaniam, J. Shang, M Zhang, K. Duffy, B. Huber, M. Vinson, W. Brugger, M. Pule Haematology, University College London, London; Manchester Royal Infirmary, Manchester, United Kingdom; VHIO Vall d’Hebron Hospital, Barcelona, Spain; Freeman H...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727145	Similarly, when EGF replaced insulin (Figure 4, #6–7), there was a clear enhancement in staining intensity compared to all other formulations (Figure 4, #C,1–5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774747	For example, in studies by Rossig et al., and Savoldo et al., CAR-VST lysed autologous LCL effectively, maintaining their MHC-restricted killing capacity (81, 82).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594588	A quantitative analysis of the processes of thrombus formation in cardiovascular diseases will provide an opportunity to select specific anticoagulant and thrombolytic drugs under conditions of preserved hemostasis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6892818	Results are representative of three independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "are", "representative", "of", "three", "independent", "experiments", "." ] } ]
PMC11739504	Finally, in ΔNLS-Kat2b-transfected shKat2b cells, a nearly complete recovery was observed with ciliary localization of IFT52, analogous to the shControl cells.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], ...
PMC10936243	the welfare, just that sometimes, they’ve been dragging with too much workload and everything, and then they want everything to work fast.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11087055	Vorticity plots, displaying averaged measure of the local rotation during each time period.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Vorticity", "plots", ",", "displaying", "averaged", "measure", "of", ...
PMC11449273	Nuclei were stained with DAPI (1:2000 in PBS) and coverslips were viewed using a Zeiss confocal microscope.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nuclei", "were", "stained", "with...
PMC10723784	The latter event is in addition to the loss of mitochondrial membrane potential, which may also lead to an increase in the level of ROS. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11789597	MM cells expressing shNC or shCAV1 were co‐cultured with iBMMCs for 6 h and incubated with Cell‐ID Cisplatin (Standard BioTools) for 5 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	In a multivariate Cox regression analysis model association of higher ePVS with increased thrombotic risk (HR 3.22, P=0.019) was present independently of WBC (HR 1.02, P=0.003), whereas JAK2 mutational status (HR 2.74, P=0.080) and cardiovascular risk factors (HR 7.12, P=0.060) retained marginal significance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: There were 404 subjects (268 HbSS, 118 HbSC, 17 HbS beta thal, 1 HbS beta 0).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results...
PMC10996034	These in vitro cellular results confirmed that the expression of MMP1 and ZYX was significantly upregulated, and the expression of UNC5C was significantly downregulated in A2780/Taxol cells, demonstrating that the three gene targets are potential and promising molecular markers of Taxol resistance in EOC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11317131	The different mutations had a variety of synergistic and antagonistic effects on one another.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "different", "mutations", "had", "a", "variety", "of", "sy...
PMC11794847	A-B: CCK8 assay was performed in lung cancer cells co-cultured with control, jurkat, and activated T cells; C-E: Colony formation assay was performed in lung cancer cells co-cultured with control, jurkat, and activated T cells; F–H: EdU assay was performed in lung cancer cells co-cultured with control, jurkat, and acti...	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11528603	After being activated, they indirectly stimulate the initial caspases (i.e., caspase 9), which, in turn, cleave effector procaspases 3/7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10291556	In the control dish, cancerous HCT-116 cells of epithelial, tile-like morphology occupied the surface along with fibrous non-cancerous MRC-5 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "...
PMC11806613	Bottom, image of isolated tumors (left) and tumor weights (right) (each group, n = 6) Effects of OST-01 on oncogenic activities in TNBC cells in vitro and tumor growth in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10899471	Further, BATF2 expression was reduced by miR-939-3p mimic and increased by miR-939-3p inhibitor in both HT-1080 and SW-982 cells ( Figures 2D–G ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "...
PMC10024132	Furthermore, the cytotoxic actions of γ9δ2 T cells mediated by γδTCR, NKG2D, DNAM1, and NKp30 might enhance the therapeutic effects over CD19 recognition alone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11513011	Considering the effect of DIB in acute myeloid leukemia cells, the mechanism of DIB activation of caspases in bladder cancer cells may be related to Ca release or the destruction of cellular organelles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11564322	Therefore, we decided to study the mTOR and PPARγ protein expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "we", "decided", "to", "study", "the", "mTOR", "and", "PP...
PMC3675084	BPR0L075 treatment induced down-regulation of Bcl-XL without changing of Bcl-2 levels in resistant cells (Figure 5C, D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BPR0L075", "treatment", "ind...
PMC10291556	NMR reduction studies were also undertaken where excess equivalents of reducing agents GSH or ascorbic acid were added to the sample before undertaking multiple NMR measurements over a 48 h period at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10899471	qPCR analysis of miR-939-3p expression in the xenografts. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "qPCR", "analysis", "of", "miR-939", "-", "3p", "expression", "in", "the", "xenografts...
PMC10589262	The efficacy of these inhibitors in combination with ER stress-inducing drugs, such as bortezomib and 17AAG, were further evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "efficacy", ...
PMC11655498	Integrating metabolomics with proteomics may reveal additional vital metabolic pathways altered by EBV infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Integrating", "metabolomics", "with", "proteomics", "may", "reveal", "...
PMC5925824	Panel b: Gene expression analysis of cell lysate from the mixed leukocyte reactions was performed using QuantiGene Plex assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Panel", "b", ":", "Gen...
PMC11306019	The combination of GA, EGC, and EGCG at physiological concentrations completely reverse the effect of BTZ. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "combination", "of", "GA", ...
PMC11785489	We observe elevated CDR3 hydrophobicity in KIR+HELIOS+CD8 T cells, consistent with a previous report.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "observe", "elevated", "CDR3", "hydrophobicity", "in", ...
PMC2777936	Gene expression of Wnt ligands and Frizzled receptors in human EC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Gene", "expression", "of", "Wnt", "ligands", "and", "Frizzled", "receptors", ...
PMC11785489	Consistent with our input to rCCA, we used one cell selected at random to represent each expanded clone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consistent", "with", "our", "inpu...
PMC11727062	However, research by Zhang et al. (2021) has demonstrated that the local dermal injection of Garcinia cambogia acid is not only efficacious in treating melanoma but also mitigates its toxic effects on various organs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519567	D Heatmap shows the expression of representative downregulated tumor suppressor genes upon SS18-SSX expression in BJ fibroblasts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "D", "Heatmap", "shows", "the", "expressi...
PMC11747949	Tumor size was calculated as follows: volume = (Dd π)/6, where D is the longer measurement and d is the shorter one.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	G. S. Nowakowski, D. H. Yoon, E. Joffe, P. L. Zinzani, L. Sabatelli, E. E. Waltl, C. G. Alvero, G. Hess, P. Riedell, K. Kim, D. Brixner, G. Salles Division of Hematology, Mayo Clinic, Rochester, United States of America; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746942	Scale bars: 20 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ":", "20", "μm", "." ] } ]
PMC9429973	For stable patients the threshold was higher than what it should be which means that the clinicians don’t follow the guidelines in this regard.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11627133	Comparison of bifunctional aptamers to antibodies in CLSM and SMLM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparison", "of", "bifunctional", "aptamers", "to", "antibodies", "in", "CLSM", "and", "SMLM", ...
PMC8427838	First, we examined whether TMIGD1 can affect Lysine 40 (K40) acetylation of tubulin in 786-0 cells, because K40 acetylation is critically important for microtubular dynamics and stability .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O"...
PMC9592219	We obtained 374 HCC tissue samples and 50 normal liver tissue samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "obtained", "374", "HCC", "tissue", "samples", "and", "50", "normal", ...
PMC10698968	A well distinguishable neoformation was visible in all the CAMs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "well", "distinguishable", "neoformation", "was", "visible", "in", "all", "the", "CAMs", ...
PMC6450504	and (d) Cell cycle distribution depending on the gating outlined in figure S2a for different time points, treatments, and PTX concentrations. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11640476	This is due to the loss of direct correlation between the resazurin reduction and the number of viable cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "due", "to", "...
PMC5261804	Of those 15 PPIs, six included JAK1 as a binding partner, two included JAK2, and one was the JAK1-JAK2 interaction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", ...
PMC5363531	Plots display the progressive time-depending wound healing, in pixel units (px), under different drugs conditions (D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Plots", "dis...
PMC11705484	AGGCUGG/A was the top mA‐modified motif; the HMOX2 mRNA mA peak diminished upon TRMT61A knockdown (Figure S2F,G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AGGCUGG/A", ...
PMC9429973	Moreover, age at diagnosis was also the independent prognostic factor for CSS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "age", "at", "diagnosis", "was", "also", "the", "inde...
PMC9429973	Toll-like receptor 9 (TLR9) is an intracellular pattern recognition receptor, and a potential contributor to CLL cell chemotaxis and tumour maintenance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11367146	The average binding affinity of docked complexes including BCL2_daucosterol BCL2_gigantol, ESR1_daucosterol, ESR1_gigantol, MMP9_daucosterol, MMP9_gigantol were −48.28, −32.83, −38.08, −36.22, −42.97 and −32.05 kcal/mol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10809689	Results were analyzed by using Flowjo v10.5.3 software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "were", "analyzed", "by", "using", "Flowjo", "v10.5.3", "software", "." ] } ]
PMC11036064	Also, hsa-miR-34a-5p significantly increases the temozolomide-mediated cell cycle arrests at the sub-G1 of A172 cells (P-value < 0.0001) (Figure 10A, B(Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747160	The Nickel columns were washed with Washing Buffer (6 M Guanidine hydrochloride, 200 mM NaCl, and 50 mM sodium phosphate, pH 7) to remove nonspecifically bound proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	M. Zabczyk, J. Natorska, A. Undas Jagiellonian University Medical College, Krakow, Poland Background: Antithrombin is the key inhibitor of coagulation factors and its deficiency is associated with increased risk of venous thromboembolism (VTE).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3734024	More work is required, however, to clarify the differences and similarities of B cells stimulated with IL-21 or IL-5, as these two types of B cells might also target different cells in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8357004	Both compounds inhibited cell growth, induced apoptosis, and up-regulated the p16INK4a, p14ARF, p15INK4b gene significantly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "compounds", "inhibited", ...
PMC11544122	Primers were used to amplify template DNA encoding FLAG-CXCR4-YFP using Platinum SuperFi DNA polymerase and circularized with KLD enzyme mix.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primers", "were", "used", ...
PMC9429973	Aims: To assess the impact of selective CTPS1 inhibition on the proliferation of, and cytokine release from, human T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ...
PMC10545062	Boluses that previously delivered over a 2-minute period were now divided into one-minute boluses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Boluses", "that", "previously", "delivered", "over", "a", "2-minute", ...
PMC11543935	To examine the impact of an EP, it is essential to monitor the temperature rise to ensure that cells are not at risk of undergoing thermal necrosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11342785	We quantified the droplet intensity distributions (Fig. 2F) and bundling efficiency (Fig. 2G) of these synMAPs and compared them to native TPPP-FL and truncations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	Nucleotide heterogeneity of 4004 annotated HIV-1 strains is depicted in a heat-map form demonstrating entropic (blue) or conserved (red) loci in three reading frames.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11779960	c Representative TCRβ clonotype diversity in selected patients (top 10 TCRβ clonotypes reported).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "c", "Representative", "TCRβ", "clonotype", "diversity", "in", ...
PMC11012012	SLAMF3/CD229 expression in BL cell lines was also analyzed by Romero et al. (2004) who found that SLAMF3/CD229 was positive in Daudi (75–100% positive cells) and partially positive in Namalwa (20–50%), Raji (50–75%), and Ramos (20–50%) cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", ...
PMC9429973	Results: In pts treated with single-agent Ibr for 1 cycle, MCL-1, BCL-XL and BCL-2 expression decreased by 74%, 95% and 10%, respectively, in lymph node emigrant (CD5 CXCR4) CLL cells, confirming increased BCL-2-dependence and corresponding inhibitor sensitization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10745221	These images are representative of two individual experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "images", "are", "representative", "of", "two", "individual", "experiments", "." ] } ]
PMC11534377	In the control group, cells exhibited normal migration and wound closure, with the gap nearly closing by 80 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "cont...
PMC11806613	Right, tumor weights (MDA-MB-231: each group, n = 7; BT474: each group, n = 8).	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC6442998	A model emerges (cartoon Figure 6) in which GIST cells depend for their survival/proliferation on two pathways, KIT-MAPK/ERK and YAP, in parallel, the outcome (death/survival) being a matter of balance and relative strength of the two drivers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224206	The energy requirements of developmental processes occurring in the embryo during the preimplantation stage are relatively low and are largely satisfied through mitochondrial oxidative metabolism, with a minor, but important contribution from aerobic glycolytic production of lactate .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8427838	Fig. 6Knockout of moesin in 786-0 cells inhibits TMIGD1-dependent α-tubulin acetylation and F-actin orientation.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "6Knockout", "of", "moesin", ...
PMC10818573	Therefore, a simple system that allows for the rapid detection of EBV in multiple contexts, including both cell culture and tissue samples, remains necessary.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10073922	Two main strategies have suggested for increasing tumor specificity of gene therapy including targeted transfer to tumor cells via tumor specific receptors and targeted transcription of anti-tumor genes using TSPs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11389534	The review highlights the current understanding of mechanisms and functions of UFMylation across a spectrum of immune responses, including IFN‐γ‐mediated antiviral defence, inflammatory signalling pathways, B‐cell development and function, PD‐1/PD‐L1 checkpoint modulation, the mucosa immunity, and the potential crossta...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9118379	Of the 320 spectra, 99, 71, and 71 spectra were assigned to variant peptides by three, two, and only one OMS tools, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

iMCD patients were identified by CD-specific ICD-10 diagnosis code (D47.Z2), negative HHV-8 and HIV status, and diagnostic or laboratory claims for ≥2 minor criteria required to diagnose iMCD.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8916024

An analysis of gut biomarker features of the adult and juvenile snails. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "analysis", "of", "gut", "biomarker", "features", "of", "the", "...

PMC9910796

In contrast, the subcellular localization of pp220 was drastically altered when co-expressed with pEP84R (Fig 5E, S7E and S7F Fig).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC10297204

RFS was lower in the control group.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RFS", "was", "lower", "in", "the", "control", "group", "." ] } ]

PMC11201989

The similarities between the primary cilium and immune synapse (interface formed between an antigen-presenting cell and the effector immune cell) have been increasingly recognized .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9429973

These results make our PI-resistant models, an attractive preclinical model to test new therapeutic strategies to overcome PI resistance in MM.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "res...

PMC11188874

Transfected cell lines were selected in complete medium with selection antibiotic.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transfected", "cell", "lines", "were", "selected", "in", "complete", "medium", "with", ...

PMC11750712

Adverse events over the first 28 days after CAR infusion were graded according to Common Terminology Criteria for Adverse Events (version 5.0).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11612315

Mechanical allodynia and thermal hyperalgesia were evaluated in separate experiments in a time-dependent manner.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mechanical", "allodynia", "and", "thermal", "hyperalgesia", "were", "e...

PMC6617630

JQ1, OTX, and I-BET at lower concentration (0.05 or 1μM) had a minimum inhibitory effect on proliferation of DHL and THL cells, although at higher concentrations such as 2.5 μM or 5 μM all of the three inhibitors significantly abrogated the proliferation of DHL/THL DLBCL cells and the inhibitory effect was similar to t...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "...

PMC9429973

Among them, 7 patients received PCIOD program and 14 patients received VTLP like program.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "them", ",", "7", "patients", "received", "PCIOD", ...

PMC11730311

Mice used for the pharmacokinetic study were housed in the AAALAC accredited animal facility at Gubra, Denmark.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "used", "for", "the", "pharmaco...

PMC11247842

Without a criterion to further prioritize these genes, we only kept the ones with biological support (see Additional file 1: Table S9) for downstream analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11243198

The higher efficacy of GANT61 analogs in reducing Gli1 expression compared to GANT61 at 96 h may be attributed, at least in part, to the reported low level of stability of GANT61 .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10376064

First, we confirmed that DMF was stable in neutral drinking water (pH ~7.2) using spectroscopic measurements (Appendix A, Figure A1).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC8540611

Cellular uptake was critically small.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cellular", "uptake", "was", "critically", "small", "." ] } ]

PMC11760643

Furthermore, significantly greater P2X7 expression on CD4 effector memory cells compared with CD4 naive and central memory cells was shown previously, which was not observed here.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Results: In the acute leukemias group mortality was 25-82%, depending on the disease entity, disease status, age and intensity of the antineoplastic treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11740508

Thus our PDX experimental result with TM00091, which bears the C61G mutation, may not be entirely irrelevant.

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PMC11656048

Therefore, 0.75 uM, 1.5 uM and 3 uM of shikonin concentration were selected for the following experiments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "0.75", "uM", ...

PMC9341513

Cycle threshold values were normalized by comparison with GAPDH expression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cycle", "threshold", "values", "were", "normalized", "by", "comparison", "with", "GAPDH", "expre...

PMC11285179

Pearson or Spearman correlation was applied to analyze the relationship between the expression scores of two genes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pearson", "or", "Spearman", "correlation", "was",...

PMC11656380

Using CCRF-CEM cells, we determined the mode of cell death induced by Tat-Ram13 and compared it to apoptosis induced by the DNA topoisomerase II inhibitor etoposide.

[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8481254

In previous studies, we confirmed that CA can effectively inhibit the expression of YAP, an important oncoprotein in HCC cells, and the proliferation of HCC cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

K. Cwynarski, E. Tholouli, G. Iacoboni, T. Menne, D. Irvine, L. Wood, N. Balasubramaniam, J. Shang, M Zhang, K. Duffy, B. Huber, M. Vinson, W. Brugger, M. Pule Haematology, University College London, London; Manchester Royal Infirmary, Manchester, United Kingdom; VHIO Vall d’Hebron Hospital, Barcelona, Spain; Freeman H...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11727145

Similarly, when EGF replaced insulin (Figure 4, #6–7), there was a clear enhancement in staining intensity compared to all other formulations (Figure 4, #C,1–5).

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PMC11774747

For example, in studies by Rossig et al., and Savoldo et al., CAR-VST lysed autologous LCL effectively, maintaining their MHC-restricted killing capacity (81, 82).

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PMC11594588

A quantitative analysis of the processes of thrombus formation in cardiovascular diseases will provide an opportunity to select specific anticoagulant and thrombolytic drugs under conditions of preserved hemostasis.

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PMC6892818

Results are representative of three independent experiments.

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PMC11739504

Finally, in ΔNLS-Kat2b-transfected shKat2b cells, a nearly complete recovery was observed with ciliary localization of IFT52, analogous to the shControl cells.

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PMC10936243

the welfare, just that sometimes, they’ve been dragging with too much workload and everything, and then they want everything to work fast.

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PMC11087055

Vorticity plots, displaying averaged measure of the local rotation during each time period.

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PMC11449273

Nuclei were stained with DAPI (1:2000 in PBS) and coverslips were viewed using a Zeiss confocal microscope.

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PMC10723784

The latter event is in addition to the loss of mitochondrial membrane potential, which may also lead to an increase in the level of ROS. ,

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PMC11789597

MM cells expressing shNC or shCAV1 were co‐cultured with iBMMCs for 6 h and incubated with Cell‐ID Cisplatin (Standard BioTools) for 5 min.

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PMC9429973

In a multivariate Cox regression analysis model association of higher ePVS with increased thrombotic risk (HR 3.22, P=0.019) was present independently of WBC (HR 1.02, P=0.003), whereas JAK2 mutational status (HR 2.74, P=0.080) and cardiovascular risk factors (HR 7.12, P=0.060) retained marginal significance.

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PMC9429973

Results: There were 404 subjects (268 HbSS, 118 HbSC, 17 HbS beta thal, 1 HbS beta 0).

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PMC10996034

These in vitro cellular results confirmed that the expression of MMP1 and ZYX was significantly upregulated, and the expression of UNC5C was significantly downregulated in A2780/Taxol cells, demonstrating that the three gene targets are potential and promising molecular markers of Taxol resistance in EOC.

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PMC11317131

The different mutations had a variety of synergistic and antagonistic effects on one another.

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PMC11794847

A-B: CCK8 assay was performed in lung cancer cells co-cultured with control, jurkat, and activated T cells; C-E: Colony formation assay was performed in lung cancer cells co-cultured with control, jurkat, and activated T cells; F–H: EdU assay was performed in lung cancer cells co-cultured with control, jurkat, and acti...

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PMC11528603

After being activated, they indirectly stimulate the initial caspases (i.e., caspase 9), which, in turn, cleave effector procaspases 3/7.

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PMC10291556

In the control dish, cancerous HCT-116 cells of epithelial, tile-like morphology occupied the surface along with fibrous non-cancerous MRC-5 cells.

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PMC11806613

Bottom, image of isolated tumors (left) and tumor weights (right) (each group, n = 6) Effects of OST-01 on oncogenic activities in TNBC cells in vitro and tumor growth in vivo.

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PMC10899471

Further, BATF2 expression was reduced by miR-939-3p mimic and increased by miR-939-3p inhibitor in both HT-1080 and SW-982 cells ( Figures 2D–G ).

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PMC10024132

Furthermore, the cytotoxic actions of γ9δ2 T cells mediated by γδTCR, NKG2D, DNAM1, and NKp30 might enhance the therapeutic effects over CD19 recognition alone.

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PMC11513011

Considering the effect of DIB in acute myeloid leukemia cells, the mechanism of DIB activation of caspases in bladder cancer cells may be related to Ca release or the destruction of cellular organelles.

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PMC11564322

Therefore, we decided to study the mTOR and PPARγ protein expression.

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PMC3675084

BPR0L075 treatment induced down-regulation of Bcl-XL without changing of Bcl-2 levels in resistant cells (Figure 5C, D).

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PMC10291556

NMR reduction studies were also undertaken where excess equivalents of reducing agents GSH or ascorbic acid were added to the sample before undertaking multiple NMR measurements over a 48 h period at 37 °C.

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PMC10899471

qPCR analysis of miR-939-3p expression in the xenografts. (

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PMC10589262

The efficacy of these inhibitors in combination with ER stress-inducing drugs, such as bortezomib and 17AAG, were further evaluated.

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PMC11655498

Integrating metabolomics with proteomics may reveal additional vital metabolic pathways altered by EBV infection.

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PMC5925824

Panel b: Gene expression analysis of cell lysate from the mixed leukocyte reactions was performed using QuantiGene Plex assay.

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PMC11306019

The combination of GA, EGC, and EGCG at physiological concentrations completely reverse the effect of BTZ. (

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PMC11785489

We observe elevated CDR3 hydrophobicity in KIR+HELIOS+CD8 T cells, consistent with a previous report.

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PMC2777936

Gene expression of Wnt ligands and Frizzled receptors in human EC cells.

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PMC11785489

Consistent with our input to rCCA, we used one cell selected at random to represent each expanded clone.

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PMC11727062

However, research by Zhang et al. (2021) has demonstrated that the local dermal injection of Garcinia cambogia acid is not only efficacious in treating melanoma but also mitigates its toxic effects on various organs.

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PMC11519567

D Heatmap shows the expression of representative downregulated tumor suppressor genes upon SS18-SSX expression in BJ fibroblasts.

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PMC11747949

Tumor size was calculated as follows: volume = (D*d *π)/6, where D is the longer measurement and d is the shorter one.

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PMC9429973

G. S. Nowakowski, D. H. Yoon, E. Joffe, P. L. Zinzani, L. Sabatelli, E. E. Waltl, C. G. Alvero, G. Hess, P. Riedell, K. Kim, D. Brixner, G. Salles Division of Hematology, Mayo Clinic, Rochester, United States of America; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South ...

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PMC11746942

Scale bars: 20 μm.

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PMC9429973

For stable patients the threshold was higher than what it should be which means that the clinicians don’t follow the guidelines in this regard.

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PMC11627133

Comparison of bifunctional aptamers to antibodies in CLSM and SMLM.

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PMC8427838

First, we examined whether TMIGD1 can affect Lysine 40 (K40) acetylation of tubulin in 786-0 cells, because K40 acetylation is critically important for microtubular dynamics and stability .

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PMC9592219

We obtained 374 HCC tissue samples and 50 normal liver tissue samples.

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PMC10698968

A well distinguishable neoformation was visible in all the CAMs.

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PMC6450504

and (d) Cell cycle distribution depending on the gating outlined in figure S2a for different time points, treatments, and PTX concentrations. (

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PMC11640476

This is due to the loss of direct correlation between the resazurin reduction and the number of viable cells.

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PMC5261804

Of those 15 PPIs, six included JAK1 as a binding partner, two included JAK2, and one was the JAK1-JAK2 interaction.

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PMC5363531

Plots display the progressive time-depending wound healing, in pixel units (px), under different drugs conditions (D).

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PMC11705484

AGGCUGG/A was the top mA‐modified motif; the HMOX2 mRNA mA peak diminished upon TRMT61A knockdown (Figure S2F,G).

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PMC9429973

Moreover, age at diagnosis was also the independent prognostic factor for CSS.

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PMC9429973

Toll-like receptor 9 (TLR9) is an intracellular pattern recognition receptor, and a potential contributor to CLL cell chemotaxis and tumour maintenance.

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PMC11367146

The average binding affinity of docked complexes including BCL2_daucosterol BCL2_gigantol, ESR1_daucosterol, ESR1_gigantol, MMP9_daucosterol, MMP9_gigantol were −48.28, −32.83, −38.08, −36.22, −42.97 and −32.05 kcal/mol.

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PMC10809689

Results were analyzed by using Flowjo v10.5.3 software.

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PMC11036064

Also, hsa-miR-34a-5p significantly increases the temozolomide-mediated cell cycle arrests at the sub-G1 of A172 cells (P-value < 0.0001) (Figure 10A, B(Fig.

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PMC10747160

The Nickel columns were washed with Washing Buffer (6 M Guanidine hydrochloride, 200 mM NaCl, and 50 mM sodium phosphate, pH 7) to remove nonspecifically bound proteins.

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PMC9429973

M. Zabczyk, J. Natorska, A. Undas Jagiellonian University Medical College, Krakow, Poland Background: Antithrombin is the key inhibitor of coagulation factors and its deficiency is associated with increased risk of venous thromboembolism (VTE).

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PMC3734024

More work is required, however, to clarify the differences and similarities of B cells stimulated with IL-21 or IL-5, as these two types of B cells might also target different cells in vivo.

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PMC8357004

Both compounds inhibited cell growth, induced apoptosis, and up-regulated the p16INK4a, p14ARF, p15INK4b gene significantly.

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PMC11544122

Primers were used to amplify template DNA encoding FLAG-CXCR4-YFP using Platinum SuperFi DNA polymerase and circularized with KLD enzyme mix.

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PMC9429973

Aims: To assess the impact of selective CTPS1 inhibition on the proliferation of, and cytokine release from, human T cells.

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PMC10545062

Boluses that previously delivered over a 2-minute period were now divided into one-minute boluses.

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PMC11543935

To examine the impact of an EP, it is essential to monitor the temperature rise to ensure that cells are not at risk of undergoing thermal necrosis.

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PMC11342785

We quantified the droplet intensity distributions (Fig. 2F) and bundling efficiency (Fig. 2G) of these synMAPs and compared them to native TPPP-FL and truncations.

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PMC8633974

Nucleotide heterogeneity of 4004 annotated HIV-1 strains is depicted in a heat-map form demonstrating entropic (blue) or conserved (red) loci in three reading frames.

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PMC11779960

c Representative TCRβ clonotype diversity in selected patients (top 10 TCRβ clonotypes reported).

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PMC11012012

SLAMF3/CD229 expression in BL cell lines was also analyzed by Romero et al. (2004) who found that SLAMF3/CD229 was positive in Daudi (75–100% positive cells) and partially positive in Namalwa (20–50%), Raji (50–75%), and Ramos (20–50%) cells .

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PMC9429973

Results: In pts treated with single-agent Ibr for 1 cycle, MCL-1, BCL-XL and BCL-2 expression decreased by 74%, 95% and 10%, respectively, in lymph node emigrant (CD5 CXCR4) CLL cells, confirming increased BCL-2-dependence and corresponding inhibitor sensitization.

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PMC10745221

These images are representative of two individual experiments.

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PMC11534377

In the control group, cells exhibited normal migration and wound closure, with the gap nearly closing by 80 hours.

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PMC11806613

Right, tumor weights (MDA-MB-231: each group, n = 7; BT474: each group, n = 8).

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PMC6442998

A model emerges (cartoon Figure 6) in which GIST cells depend for their survival/proliferation on two pathways, KIT-MAPK/ERK and YAP, in parallel, the outcome (death/survival) being a matter of balance and relative strength of the two drivers.

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PMC11224206

The energy requirements of developmental processes occurring in the embryo during the preimplantation stage are relatively low and are largely satisfied through mitochondrial oxidative metabolism, with a minor, but important contribution from aerobic glycolytic production of lactate .

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PMC8427838

Fig. 6Knockout of moesin in 786-0 cells inhibits TMIGD1-dependent α-tubulin acetylation and F-actin orientation.

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PMC10818573

Therefore, a simple system that allows for the rapid detection of EBV in multiple contexts, including both cell culture and tissue samples, remains necessary.

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PMC10073922

Two main strategies have suggested for increasing tumor specificity of gene therapy including targeted transfer to tumor cells via tumor specific receptors and targeted transcription of anti-tumor genes using TSPs.

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PMC11389534

The review highlights the current understanding of mechanisms and functions of UFMylation across a spectrum of immune responses, including IFN‐γ‐mediated antiviral defence, inflammatory signalling pathways, B‐cell development and function, PD‐1/PD‐L1 checkpoint modulation, the mucosa immunity, and the potential crossta...

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PMC9118379

Of the 320 spectra, 99, 71, and 71 spectra were assigned to variant peptides by three, two, and only one OMS tools, respectively.

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