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Primary or secondary neurondocrine (ne) tumours of the female genital tract are rare . Cervical small cell carcinoma and ovarian carcinoids are the most common gynaecological ne tumours . Neuroendocrine tumours comprise a set of neoplasms that arises from the diffuse neuroendocrine cell system . These tumours are more ... |
Adenoid cystic carcinoma (adcc) is a malignant salivary gland tumor that was first described by billroth in 1859 under the name cylindroma attributing to its cribriform appearance formed by the tumor cells with cylindrical pseudolumina or pseudospaces . The term adenoid cystic carcinoma was introduced by ewing (foote a... |
The quantity of trauma victims and the management involved in attending them leads to a great workload in most hospitals and places an enormous amount of pressure on the health care system . Furthermore, traumatic injuries have been reported as the leading cause of death in the first 40 years of life and appear to be o... |
The influence of protecting groups on the reactivity and selectivity of glycosyl donors is a widely recognized and exploited phenomenon . The corresponding influence of protecting groups on the anomeric equilibrium, while evident for many years, is less widely studied and exploited . Recent examples of the latter inclu... |
Familial hemiplegic migraine (fhm) is an autosomal dominant rare type of migraine with aura characterized by some degree of hemiparesis . Fhm1, fhm2 and fhm3 are caused by mutations in the ion - channel genes cacna1a, atp1a2 and scn1a, respectively [24]. The majority of fhm families have pure fhm, but cerebellar ataxia... |
A few days later, four more cases occurred among postal workers at the brentwood mail processing facility in the washington area . The appearance of new cases in different locations around the country suggested contamination with b. anthracis of several postal facilities . In each location, the population potentially e... |
Duodenal ulcer perforation is still a common complication of chronic peptic ulcer disease . Despite the wide spread use of anti - secretory and h. pylori eradication therapy most of the literature pertaining to the situation in the developed world, showed that the disease is largely confined to the elderly patients tak... |
Hemophilia b is a chronic hereditary disease characterized by a deficiency in factor ix (fix) activity . It is less common than hemophilia a which is due to factor viii (fviii) deficiency . According to the world federation of hemophilia global survey of 2014, 178,500 persons were identified with hemophilia across 106 ... |
Protease inhibitors have been purified from an array of leguminous and nonleguminous species encompassing torresea cearensis, erythrina caffra, dolichos lablab, crotalaria paulina, medicago scutellata [5, 6], canavalia gladiata, pisum sativum, dimorphandra mollis, swartzia pickellii, psophocarpus tetragonolobus, deloni... |
Although about two - thirds of patients with epilepsy (pwe) treated with antiepileptic drugs (aeds) reach seizure - freedom, about one - third remains drug - resistant to the current therapies.1 despite the introduction of new aeds with a better pharmacokinetic and safety profile compared to old generation aeds, today,... |
Acute intussusception is one of the most common causes of acute abdomen in infants . Management includes both surgical and non - surgical methods, with gradually increasing importance recently being accorded to the latter . Conservative measures, including hydrostatic reduction, are the methods of choice for initial ma... |
Aging, a multifactorial process of enormous complexity, is characterized by impairment of physiochemical and biological aspects of cellular functions (harman 1992). Oxidative stress, an unavoidable consequence in the metabolism of oxygen in aerobic cells, is a major factor in the aging process and, in the course of man... |
Cleft lip and palate (clp) patients are going through an extensive treatment with orthodontic and surgical correction of the position of teeth and hard and soft tissues . The aim of the primary surgery is to close the clefts of the lip and the soft palate . The aim of the secondary surgery is to close the cleft of the ... |
A rising trend in the incidence and prevalence of inflammatory bowel disease (ibd) in asia has been recognized for the past two decades . The thiopurine drugs azathioprine (aza) and mercaptopurine are widely used for the treatment of ibd and have proven to be effective in both inducing and maintaining remission of croh... |
Diabetic macular edema (dme) is a common complication of diabetic retinopathy (dr) and a leading cause of visual loss in this population [1, 2]. Major components of dme are retinal microvascular dysfunction and blood - retinal barrier (brb) breakdown with consequent increase in vascular permeability that allows plasma ... |
Diabetes is the most frequent cause of end - stage renal disease in industrialised countries [1, 2]. Clinically, diabetic nephropathy is characterized by the development of albuminuria and a subsequent decline in glomerular filtration rate . This severe complication significantly influences the risk of cardiovascular d... |
How to choose surgical approach in severe multilevel cervical cord compression case is a hot debate on spine surgery . Some surgeons think anterior surgery should be of the primary choice, because of direct decompression, restoring intervertebral height and reconstruction of stability7,12). Some surgeons prefer posteri... |
Population aging is the process by which older individuals become a proportionally larger share of the total population . It was the most distinctive global demographic event that the world witnessed in the past century and is an important event for the twenty - first century too . It was initially experienced by the m... |
Day care or ambulatory anaesthesia is as old as the history of anaesthesia itself . In the last few decades, it has gained significant popularity mainly because of the enormous cost savings and has therefore been accepted by the hospitals, patients and the insurance companies alike . However, the quality and excellence... |
The relationship between the clotting cascade and the promotion or inhibition of the anti - inflammatory response continues to be defined through basic research . The potential key role of proteins that were originally believed to be exclusively involved in coagulation in the inflammatory response provides an exciting ... |
Myelofibrosis (mf) belongs to the category of myeloproliferative neoplasms (mpns) and may present as a primary disorder (primary myelofibrosis [pmf]) or evolve from polycythaemia vera (pv) or essential thrombocythaemia (et) to post - pv or post - et mf.1 it is characterised by the clonal proliferation of a pluripotent ... |
A 45-year - old iranian woman was referred to the private clinic in the city of hamadan for implant consultation . Her past medical history was not notable, and there was no evidence of systemic disease . She had no history of trauma to the mandible . In the extra - oral examination, intra - oral examination revealed n... |
Controversy exists as to whether endodontic procedures are the primary cause for loss of strength . Panitvisai and messer (1995) reported that cuspal deflection increased with increasing the extension of cavity preparations and was greatest when endodontic access was incorporated into a preparation . It has been report... |
Dichlorvos (dimethyl-2, 2-dichloro vinyl phosphate) is an organophosphorous (op) insecticide with moderate human toxicity, used for insect control in food storage areas, greenhouses, barns and control of insects on livestock . Parenteral dichlorvos administration with suicidal intention is rarely reported in the litera... |
Transesophageal echocardiography (tee) is considered to be safe and relatively noninvasive diagnostic tool,1) however severe complications have been reported . The incidence of major tee - related complications range from 0.2% to 0.5% and mortality is reported to be <0.01%.2345) among these complications, problems rela... |
It has been reported that the prevalence and incidence of dementia in the united states have been either stable or even declining over the last 2 decades of the 1990s . This question is particularly relevant to the case of japan which is an economically advanced country like the us, but is believed to have a different ... |
Chronic low back pain (clbp) refers to chronic pain around the lumbar vertebra sustained for over three months without serious pathological characteristics, regardless of the existence of sciatalgia1 . Clbp causes pain and changes in the muscles, as well as decreases in contractile force and muscle activity . Studies o... |
To learn about the normal anatomy of the neural tube on mri to recognise the mr appearance of neural tube defects to understand the value of mri in assessing ntds technological developments in diagnostic imaging have improved the diagnosis and treatment of congenital anomalies immensely, and this progress is especially... |
Patient acuity has been increasing, patient turnover is higher, and patients are frequently of advanced age with several comorbid disorders . Limited resources and the pressure for higher efficiency can result in the suboptimal delivery of healthcare . During treatment within the healthcare system, a significant percen... |
Slc / ccl21, normally expressed in high endothelial venules and in t cell zones of spleen and lymph nodes, strongly attracts t cells and dendritic cells (dc) [1 - 8]. Slc / ccl21 recruits both nave lymphocytes and antigen stimulated dc into t cell zones of secondary lymphoid organs, co - localizing these early immune r... |
Neonatal bacterial meningitis continues to be the most common serious infection of the central nervous system (cns) in newborns with high morbidity and mortality despite the availability of effective bactericidal antibiotics over the last sixty years [1, 2]. This high morbidity and mortality are due to inadequate knowl... |
Today, education has been assigned as an industry for human resource development for different walks of life . The students constitute the heart of the education system and they are the most affected ones by the strengths and weaknesses of the education system . The students form an identical subgroup compared to other... |
Dermatomyositis (dm) is an uncommon idiopathic inflammatory myopathy that primarily affects skeletal muscle and skin with well - characterized cutaneous findings . It has been well documented that dm carries an increased risk of malignancy and can present as a paraneoplastic syndrome to multiple types of underlying mal... |
Taken together, malaria (caused by plasmodium species), human african trypanosomiasis (hat, caused by trypanosoma brucei), chagas disease (caused by t. cruzi), and leishmaniasis (caused by leishmania species) represent diseases with an estimated combined burden of over 87 million disability - adjusted life years . Whil... |
Acute appendicitis is considered as the most frequent cause of acute abdomen in young patients with a slight predominance in males . Although its clinical diagnosis is simple, 20 - 30% of appendicitis cases are reported to be gangrenous or perforated because of delayed diagnosis, which can lead to increased morbidity a... |
They possess binding sites specific to carbohydrates and have the capacity to interact with molecules of biological fluids and those present in cellular surfaces . Lectins can substitute natural linkers and activate cellular responses through different roads of intracellular signalling or endocytosis of formed compound... |
The comingling of swine from numerous premises with varied management practices and their interaction with large numbers of exhibitors and visitors make agricultural fairs an ideal setting for the intra- and inter - species transmission of influenza a viruses (iavs) between swine and human populations . The frequency w... |
Turmeric (curcuma longa l.) of family zingiberaceae is industrially as well as pharmaceutically important crop extensively cultivated in india . It is a vegetatively propagated, polyploid crop commonly known as golden spice . Because of its multipurpose use as food preservative, spice, therapeutic agent and natural dye... |
The sense of coherence (soc), which was proposed by antonovsky is based on the salutogenic model of health . The soc is composed of three factors; (1) the stimuli derived from internal and external environments in the course of living are structured, predictable, and explicable (comprehensibility); (2) resources are av... |
Huntington's disease (hd) is an autosomal dominant, progressive neurodegenerative disorder characterized by chorea, subcortical dementia and psychiatric symptoms . The causal hd gene has been identified as it15, which has cag repeats in the open reading frame (orf, in exon 1) just following the 5end of the gene . It le... |
Walking ability is impaired in patients with peripheral arterial disease (pad) due to decreased blood flow to the skeletal muscle tissue used during walking . It has been demonstrated that walking distance is associated with the degree of impairment in the affected leg as measured by the ankle - brachial index (abi) an... |
Access to automated dna sequencing technology has made possible the rapid generation and analysis of gene transcripts expressed in organisms via expressed sequence tags (ests). This information has helped to identify those genes expressed in particular stages of development and in specialized tissues or organs . Novel ... |
The transition - metal - catalyzed amination of aryl halides has become one of the most powerful methods to construct arylamines . The development of methods to couple aryl halides with amines has been studied extensively in the past decade . Palladium - catalyzed reactions occur with a broad scope of both coupling par... |
Children diagnosed with jia were referred by pediatricians to our immuno - ophthalmology unit for ophthalmic examination . Children 10 years old or younger presenting to our clinic with intraocular inflammation were referred for pediatric consult to verify a possible jia association . Included in this study is a cohort... |
Increasing cytosolic calcium ion (ca) concentration is essential for the contraction of smooth muscle cells . The increase results from the influx of ca through the plasma membrane and release of ca from intracellular stores, mainly the sarcoplasmic reticulum (sr) [14]. Phenylephrine (pe) or angiotensin ii (ang ii) ind... |
After an information campaign in horse journals and at meetings, 278 samples of maple tree leaves, sprouts, and seeds collected by horse owners in 2014 were sent to utrecht university (uu) and rikiltwageningen ur (figs 1, 2, 3). The samples were taken from the ground, packed in plastic, and immediately sent to the labo... |
Cell migration requires the rearrangement of adhesions and cytoskeleton in response to extracellular stimuli to form a leading edge that allows directed locomotion . In most cell types, migration - related adhesive structures are composed of integrin heterodimers and intracellular associated proteins clustered in plaqu... |
Ventriculoperitoneal (vp) shunting is commonly utilized as a diversion procedure for patients with hydrocephalus . Multiple techniques for initial placement of the catheters have been described, including conventional minilaparotomy, peel - away introducer sheaths, as well as full laparoscopic approaches . Vp shunts fa... |
Ventilator - associated pneumonia (vap) is defined as pneumonia occurring more than 48 hours after patients have been intubated and received mechanical ventilation . Vap is the most common nosocomial infection in the intensive care unit (icu) with an incidence ranging from 8% to 28% in intubated mechanically ventilated... |
Alpha1-adrenergic receptors (1-ars) are a heterogeneous family of g - protein - coupled receptors that present in most human and animal tissues, and there are considerable variations in the expression levels of 1-ar subtypes in various tissues of different species [14]. 1-ars play important roles in regulating physiolo... |
While the occurrence of dental caries has decreased during the last decades, researchers had focused on non - carious lesions, including erosion . Dental erosion is an acid - induced tooth loss not involving microorganisms caused by external and/or internal acids . Recent studies indicate a meaningful increase in denta... |
Allergic diseases are among the most common chronic diseases throughout the world and the prevalence of atopic diseases in childhood has significantly increased during the past several decades [2, 3]. Although there is a general consensus on the importance of a genetic predisposition for atopic diseases, only changes i... |
Mainly for safety reasons, many patients and their families are looking for a seizure detection system that is efficient, comfortable, and easy to use . This implies that such a system should have a high detection sensitivity (detect as many seizures as possible) and low false alarm rate; it should be unobtrusive, wire... |
Angiomyolipoma (aml) is a benign mesenchymal tumour consisting of varying amounts of mature adipose tissue, smooth muscle, and thick walled blood vessels . It is relatively rare benign tumour appearing in about 0.3% of general population and accounts for 3% of solid renal masses . Extra renal amls (eramls) are rare tum... |
A 67-year - old male presented to the emergency eye centre (eec) complaining of a painful right eye of 5-day duration . Clinical examination revealed a visual acuity (va) of 6/9 with minimal conjunctival injection, anterior chamber (ac) cells 1 + and posterior synechiae (ps). A diagnosis of anterior uveitis was made an... |
In 1978, primary health care was seen as the solution to the inadequate illness management systems that had developed throughout the world . It was hoped that phc would address some of the major inequalities in health that were observed by a balanced system of treatment and disease prevention . The world health organiz... |
Despite advancements in renal replacement therapy, acute kidney injury (aki) is a frequent complication with severe implications for the critically ill patient . Published mortality rates for intensive care unit patients with aki range between 30 and 70%, and aki alone remains an independent risk factor for mortality e... |
Plasma cell leukemia (pcl) is a rare disease that represents approximately 4% of plasma cell malignant disorders.1 diagnosis of pcl is established based on kyle s criteria, which includes an absolute plasma cell number accounting for greater than 2000/l or 20% of white blood cell differentiation.2 pcl consists of two v... |
Fitz hugh curtis syndrome is an extra - pelvic manifestation of pelvic inflammatory disease (pid) and is characterized by perihepatic adhesions between liver capsule and diaphragm or anterior peritoneal surface(13). Most fitz hugh curtis syndrome patients are women of child bearing age and rarely has the syndrome been ... |
Chemical shifts are now routinely used as a source of local conformational restraints in the structure determination of proteins by nmr, due mostly to the widespread use of programs such as talos (cornilescu et al . 1999) and shiftor / preditor (neal et al . 2006; berjanskii et al . 2006). These programs share a common... |
Sutureless clear corneal incisions are now arguably the most common incisions made to perform cataract surgery with phacoemulsification, replacing scleral tunnel and limbal incisions . There are significant differences in the effects of clear corneal and scleral or limbal incisions, related to anatomical and physiologi... |
The embryonic development of the cerebellum derives from the hindbrain from the fifth week, originating from the thickening of the dorsal alar plates . Anatomically it is formed by a median portion, the vermis, connected to two large lateral masses, the cerebellar hemispheres . The cisterna magna is located in the post... |
The protocol for this cross - sectional study was reviewed and approved by the institutional ethical committee for clinical research at the geneva university hospitals . All patients who had received a whole pancreas or an islet of langerhans transplant at the geneva university hospitals and who had regular follow - up... |
We have demonstrated that, melatonin is a bioprecursor of hypnotic acetyl metabolites produced by enzymatic acetylation of melatonin and 2-oxomelatonin under the control of acetyltransferases, most probably the nat enzymes . In 1994, in our laboratory, we developed a specific and highly sensitive gas chromatography - m... |
Over the next several decades, the number of americans living to advanced ages will increase substantially . Although many individuals will age in relatively good health, a growing number will encounter challenges associated with the burdens of chronic conditions and associated disabilities [13]. This is especially so ... |
Patients with schizophrenia (scz) exhibit a wide variety of cognitive deficits, particularly with memory (barch and ceaser, 2012; ranganath et al ., 2008). These deficits are predictive of overall functional outcome and clinical remission (bodnar et al ., 2008; green, 2006; green et al ., 2004; kahn and keefe, 2013), a... |
Ras is a multifunctional signaling molecule acting as an essential component of signal transduction pathways that regulate cellular physiology (campbell et al . Members of the ras family of proteins that are constitutively activated by point mutations play a major role in the onset of a large number of human cancers, i... |
Lipomas represent uncommon neoplasms of the oral cavity; only 1% to 5% of cases occur at this site . Based on their histopathological features of conspicuous multiple components, lipomas can be divided into some subclasses [2, 3], and the most common is the fibrolipoma [1, 3, 4]. Cases reporting on lipoma with osteo / ... |
Leydig cell tumours are rare stromal tumours of the testis accounting for 13% of testicular neoplasms . They exhibit a peak incidence in the preadolescent as well as in the older (> 50 years) age groups [1, 2, 3, 4]. The diagnosis of a malignant leydig cell tumour is not always easy since no definite histological crite... |
The prevalences of asthma, allergic rhinitis and allergic eye disease in antalya, on the south coast of turkey, have been reported as 8.2%, 10.8% and 7.5%, respectively . Allergic diseases are most likely due to complex interactions between largely unknown genetic and environmental factors [36]. The micro - array techn... |
Calcimimetics provide an alternative approach to the traditional therapy with active vitamin d and phosphate binders for the management of secondary hyperparathyroidism (shpt). Type ii calcimimetics are positive allosteric modulators of the parathyroid gland calcium - sensing receptor (car) that increase its sensitivit... |
Many neurodegenerative disorders are characterized by their presence in neural tissue of aberrant protein aggregates (see table 1). In general, these aggregates arise after the modification of a native protein . That modification could result in a conformational change of the native protein that promotes the aberrant a... |
Only those contraceptive methods are new in which synthetic steroid is used . Regarding the current status of growth, the world population is doubled every 54 years; however, in poor countries, population is doubled in less than 20 years . To complete and preserve personal health during pregnancy, the optimal use of co... |
At the end of past millennium, flexible bronchoscopy was regarded as one of the most frequently performed procedures by the physicians of multiple disciplines to inspect the airway . In our institute, the fibreoptic bronchoscopies are performed by either the pulmonologists or the anaesthetist . At many places, fibreopt... |
Charcot - marie - tooth disease (cmt) is the most common hereditary motor and sensory neuropathy, and cmt type 1a (cmt1a) neuropathy, which is the most common type of cmt, is subject to a gene dosage effect.1 the primary genetic cause of cmt1a is a duplication of pmp22 resulting from the unequal crossover between two h... |
A negative balance between the formation and resorption of bone mass can lead to the development of osteoporosis . Moreover, osteoporosisis characterized by skeletal fragility resulting from reduced bone mass and disrupted bone microarchitecture . Osteoporosis increases the risk of fracture and thus has been considered... |
Each disaster leaves an imprint on the affected population, a singular signature . A critical unmet need in the field of disaster mental / behavioral health is the capability to tailor mental health and psychosocial support (mhpss) to the unique constellation of psychological risk factors operating within each disaster... |
Cerebrovascular diseases (cvds) are associated with balance disturbances, dependency in performing daily living activities, and limited ambulation . As life expectancy increases spasticity is a speed - dependent resistance to the passive motion of muscles and tendons, developing secondary to enhanced stretch reflexes i... |
Proteinase - activated receptors (pars) belong to a family of g - protein - coupled receptors with seven transmembrane domains activated via proteolytic cleavage by serine proteinases . A total of four pars have been identified and cloned . Among them, par-1 [2, 3], par-3, and par-4 are targets for thrombin, trypsin, a... |
Relapsing chronic inflammation found in the gut of individuals affected by inflammatory bowel diseases (ibd) is a result of several overlapping factors, including dysregulation of the immune response to the enteric microbiota, genetic susceptibility, and environmental factors [1, 2]. Reactive oxygen (ros) and nitrogen ... |
Sexuality in women is a complex issue with physiological, psychological, and cultural components . Determination of sexual partner involvement, intimate relationships, and past abusive relationships is crucial in female sexual dysfunction (fsd) (1, 2). Sexual dysfunction is more prevalent among women compared to men (4... |
Laparoscopic surgery has gained widespread acceptance in a variety of procedures, ranging from gastric fundoplication to cholecystectomy . Although laparoscopic appendectomy (la) is more expensive than is open appendectomy (oa) due to the costs of the disposable equipment, and can be more technically challenging in chi... |
A major effort in the nucleocytoplasmic transport field has been directed towards the analysis of all members of the importin family, in particular with the aim of identifying specific transport cargoes . This has led to the characterization of a large number of related proteins (both importins and exportins) in all eu... |
Musculoskeletal conditions, or disorders of the muscles and bones, are the most common causes of chronic disability in the world . In the us alone, disease of the musculoskeletal system was the primary diagnosis during 83,228,000 office visits in 2009 (8.0% of total visits). A stroke can also cause many of the same phy... |
International diabetic federation estimated that in india there are 66.8 million patients in 2013, with nearly 50% undiagnosed . Diabetes was related to one million deaths and mortality was higher under age of 60 years . By 2030 there will more than 79 million diabetics, making it one of the major public health challen... |
Lactic acid was first found and described in sour milk by the swedish chemist karl wilhelm scheele (17421786) in 1780 . The swedish chemist jns jakob berzelius (17791848) found lactic acid in fluid extracted from meat in 1808 [2, 3], and the german chemist justus von liebig (18031873), who established the world's first... |
Panax ginseng (ginseng) has been used traditionally in eastern asia over thousands of years . It has been used orally to treat various diseases including hypertension, diabetes mellitus, liver and kidney dysfunction, mental disorders, and postmenopausal disorders . In addition, topical applications have also been used ... |
Chronic kidney disease (ckd) is associated with a number of comorbidities and prognosis is poor, because many patients experience progression to end - stage renal disease . Also, in the majority of patients disease progression may be altered due to more or less suitable immunosuppressive protocol treatments and therape... |
These range from various slow - growing benign tumors and low - grade malignancies to fast growing high - grade malignancies . Angiofibromas are one such group of tumors arising in this region, which present as swellings . Of these, nasal angiofibromas (nas) are the most common and nas occurring in the region other tha... |
Atherosclerotic renal artery hypertension is reported in almost 7% of adults older than 65 years1) and is associated with cardiovascular events, and may double risk of mortality2). In the 1990s, radiological angioplasty began to replace surgical revascularization . Galaria et al . Showed that percutaneous and open rena... |
Tuberculosis (tb) caused by mycobacterium tuberculosis (m. tb) continues to be a significant global health problem, affecting millions of people worldwide [1, 2]. It is a prevalent infectious disease in china, with 250,000 deaths from tb annually and 6 million active tb patients at present . The global incidence of tb ... |
A 6-year - old boy presented with a history of penetrating injury to the upper left eyelid sustained while diving head - first into a pond . On presentation, he could only perceive hand movements very close to his face . Since a computed tomography (ct) scan done at this time did not reveal the presence of any foreign ... |
Postcataract surgery endophthalmitis is a relatively uncommon but devastating complication of modern cataract surgery, and there is not complete consensus regarding the ideal practice patterns for prophylaxis . The european society of cataract and refractive surgeons (escrs) prospective multi - center interventional tr... |
Thyroid cancer is the most common endocrine neoplasia and accounts for 1% of all human cancers (1). Medullary thyroid carcinoma (mtc) is a rare neoplasm of the calcitonin - secreting thyroid cells and accounts for 510% of all thyroid cancers . Mtc can occurs as sporadically (75%) or as a part of the autosomal dominantl... |
After initial establishment and derivation of human embryonic stem cells (hesc; thomson et al ., 1998; reubinoff et al ., 2000) first the infection free status of the donors has to be addressed, in europe couples are tested before any fertility treatment is offered, but the cells themselves have to be tested, too (hova... |
To report two cases of femtosecond laser - assisted small incision deep lamellar endothelial keratoplasty (dlek) for patients with corneal endothelial decompensation by fuchs dystrophy and glaucoma irvine, ca) with 15 khz of repetition rate, was used for a 9.5 mm diameter by 400 m thickness donor corneal lamellar disse... |
The prevalence of diabetes has explosively increased worldwide, leading to an increase in the number of patients who suffer from diabetic vascular complications such as diabetic nephropathy (dn). Dn is not only the leading cause of end - stage kidney disease but also a significant risk factor for cardiovascular disease... |
Opsoclonus - myoclonus - ataxia syndrome (omas), also called kinsbourne syndrome or dancing eye syndrome, is a serious, rare, and often chronic neurological disorder . Omas consists of three main symptoms: opsoclonus (conjugate, multidirectional, chaotic eye movements), myoclonus (nonepileptic limb jerking that can als... |
To the surprise and deep disappointment of all involved in the treatment of lung cancer, several large trials did not demonstrate any benefit of tyrosine kinase inhibitors (tkis) as an addition to chemotherapy [13]. Basic and clinical research then focused on mutations of the gene for epidermal growth factor receptor (... |
Using metagenomic deep sequencing, we analyzed fecal samples from 180 infants and children ages 7 days96 months (mean 18.7 months) in tunisia who had unexplained diarrhea that tested negative for rotavirus, norovirus, astrovirus, sapovirus, adenovirus types 40 and 41, and aichi virus by reverse transcription pcr (7). T... |
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