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It may be regarded as the localized equivalent of the systemic inflammatory response seen after any trigger of inflammation, which recently has been described as systemic inflammatory response syndrome . The complex nature of surgical infections, the multifaceted aspects of treatment, and the complexity of intensive ca... |
During 20092010, serum samples from patients with suspected dengue were received by the fdoh for dengue diagnostic testing; the samples came from 16 of florida s 67counties . Specific, real - time rt - pcr (8) and igm anti - denv elisa (9). Samples with highly positive rt - pcr results were spread onto cultured ae . Al... |
Corneal epithelium is able to alter its thickness to mask subepithelial stromal irregularities and maintain a smooth anterior surface of the eye . Laser refractive surgery such as lasik alters the anterior corneal contour and leads to remodeling of corneal epithelium . We estimated the extent of the epithelial remodeli... |
This is particularly the case of the health of people living in contaminated site(s) (cs) which is affected by the legacy of past industrialization and current industrial activities, often in absence of environmental remediation . European community legislation addresses the concept of cs only in the context of the the... |
The study population included 1177 patients who underwent different types of cardiac surgeries with cardiopulmonary bypass method at sina private hospital (isfahan, iran), between april 2008 and september 2009 . All patients underwent a cardiovascular diagnostic procedure requiring the use of a contrast agent for left ... |
Colorectal cancer (crc) is one of the most common human malignancies in western countries . Colorectal adenomas have high malignancy potential when they are large in diameter and/or present with severe dysplasia and/or a villous component . Colonoscopic polypectomy has been documented to significantly reduce the incide... |
A 56-year - old man suffering from diabetes and hypertension was admitted to the neurology department in a hospital elsewhere with signs of epileptic seizure . After a brief period, a diagnostic laparotomy with gastrotomy was performed, at which over 3 liters of blood were found, but no active bleeding . The site of or... |
Today, implant therapy is regarded as an extremely reliable approach to replace missing teeth . The introduction of osseointegrated implants in dentistry represented a turning point in dental clinical practice.1 as a general principle in implant surgery implant surfaces should be surrounded by alveolar bone.2 following... |
The goal to achieve ideal pediatric drug therapy is a worldwide challenge for regulatory bodies and clinicians . Children are treated with medicines not tested for safety and efficacy and are frequently supported by the low quality of evidence . In the absence of standard prescribing information, clinicians prescribe d... |
The role of the thyroid gland in pregnancy and the impact of thyroid disorders on the course of pregnancy and development of the offspring have drawn a considerable interest in the recent years, both in the medical and in the general society . About 2 and 4% a growing body of evidence suggests that subclinical hypothyr... |
Esophageal cancer is a devastating disease with rapidly increasing incidence in western . Despite important advances in therapy,> 50% of patients have incurable disease at diagnosis and only 510% of these patients have life expectancy> 5 years . Dysphagia is the most common symptom that afflicts these patients, causing... |
A 35-year - old female presented with a painless, slowly growing mass in the right inferior orbit for the past four years . She did not complain of diminution of visual acuity, diplopia or field defect . On examination, visual acuity in both eyes the right side demonstrated a solid, non - tender, freely mobile mass in ... |
Risperidone has been reported to be effective in management of disruptive behaviors, including hyperactivity, irritability, aggression, and temper tantrums . Increased appetite, weight gain, headache, and sedation literature search revealed only four published reports of risperidone - related bleeding, including hemorr... |
Intestinal obstruction can be a result of mechanical or functional obstruction of the intestines, thereby preventing the normal transit of the products of digestion . Intestinal pseudo - obstruction (adynamic), characterized by abdominal pain, nausea, vomiting, constipation, and severe abdominal distension, is a clinic... |
The incidences were getting higher and higher . Increased intramyocellular lipid accumulation plays a very important role in obesity and diabetes, as well as their complications [2, 3]. This attracted great interest in the effect of accumulated lipid intermediates on insulin resistance [4, 5]. Lipotoxicity was regarded... |
Pelvic organ prolapse (pop) is a major healthcare problem in middle - aged and elderly women and is usually accompanied by pelvic floor dysfunction (pfd). The introduction of mesh repair in vaginal prolapse surgery showed possible advantageous results in early reports . However, pelvic floor structures progressively we... |
5-fluorouracil (5-fu) is a widely used chemotherapeutic drug and cardiac complications are not rare . However myocardial infarction, tako - tsubo - like syndrome and cardiogenic shock are also described . A 50-year - old man (weight 70 kg, height 180 cm) was admitted to a primary care hospital following an episode of s... |
A summary of methods is provided below and a detailed description of methods is included in the supplementary information . The toxin nanosponges were prepared by fusing rbc membrane vesicles on preformed poly(lactic - co - glycolic acid) (plga) nanoparticles through an established extrusion process . The size of the n... |
Hand, foot, and mouth disease (hfmd) is a common, acute, and mostly self - limiting enteroviral infection that presents with fever and vesicular lesions on the hands, feet, mouth, and frequently buttocks as characteristic features1,2,3,4). Although patients with hfmd recover without any sequelae within about 1 week, se... |
Since the increase in adiposity is related to general poor health factors such as an increase in type ii diabetes and increased incidence of coronary heart disease, exercise to reduce adiposity is recommended for the ageing population . A further consequence of the ageing process is that elderly individuals have an imp... |
Physical fitness is the ability that helps people to adapt with their environmental conditions and plays an important role in daily activities . It is highly associated to one's health status and has a striking effect on the quality of life, learning and working efficiency, and physical activity contributions . Physica... |
Optical buffers are recognized as essential components in wavelength routers, in which the packets of data can be stored for resolving packet contention problems and also delay the outgoing packets.1,2 in practice, the optical router patents have been proposed and recorded,35 which can be useful for various application... |
Assessment of effects of different assisted reproductive techniques (art) like in vitro fertilization (ivf) and intra cytoplasmic sperm injection (icsi) on speech and language development needs comprehensive studies . Some studies showed that they are more susceptible to cerebral palsy which causes speech and language ... |
A number of drugs are currently available to treat malaria; however, treatment is becoming complicated by drug resistance, toxicity, and high cost . Recently, drug resistance against the new effective drug, artemisinin, is also emerging [4, 5], and we need new effective drugs to treat malaria . Therefore, the developme... |
Alzheimer's disease (ad) is the most common cause of dementia in the aging population . This disease develops over time and leads to significant cognitive deficits affecting memory, insight, judgment, abstraction, and language functions . Ad affects more than 5 million people in the united states and this number is pro... |
For many years, the global community has observed the calamitous effects of the human immunodeficiency virus (hiv) on the human population . Hiv was historically viewed as an incurable disease that gradually progressed into acquired immune deficiency syndrome (aids) and led to one s untimely death . During his tenure (... |
Descriptive investigation of a cluster of 5 sfts cases following exposure to an index patient who died from the disease was performed . A 77-year - old male farmer who died from sfts five other cases in the cluster included a 32-year - old male intensive care unit (icu) physician (case 1), a 48-year - old male icu cons... |
Therefore, the mother's knowledge about child care influences the nature and quality of care that is given to the child . Several studies have revealed that the mothers level of education has a positive impact on her knowledge and how she deals with child health care issues. [213] our experience in pediatric practice h... |
Indications for covered self - expandable metallic airway stent removal include recurrent mucous plugging of the stent, excessive or recurrent granuloma formation, migration of the stent, stent infection, recurrence of stenosis, stent failure, stent fractures and accomplishment of treatment . Usually, it is tedious to ... |
Takayasu's arteritis (ta) is a chronic idiopathic occlusive inflammation of aorta and its major branches predominantly affecting females in over 85% of cases . The major clinical finding is loss of palpable pulses in the upper limbs and neck . The unsuspected ischemia of vital regional vascular beds may render these pa... |
Neurotransmitters (nts) are signaling molecules, which play pivotal roles in neuronal communications in the central nervous system [1, 2]. It is reported that changes in nts quantitation in several brain regions involve the development of many psychiatric diseases and neurodegenerative diseases [3, 4]. Generally, neuro... |
It plays several important physiological and pathological roles in not only reproductive system but also other systems . Estrogen disorder results in various diseases, such as endometrial diseases, skeletal diseases, and reproductive system tumors . Increasing attention has been paid to revealing of the functions of es... |
Ensemble hi - c protocol to create a method to determine the contacts in an individual nucleus (fig . 1a, supplementary information). We used male, mouse, spleenic cd4 t cells, differentiated in vitro to t helper (th1) cells to produce a population of cells (> 95% cd4), of which 69% have 2n genome content, reflecting m... |
Oligonucleotides were synthesized on an expedite automated dna / rna synthesizer (applied biosystems, foster city, ca) using nucleoside phosphoramidites purchased from glen research (sterling, va). All oligonucleotides were purified by denaturing polyacrylamide gel electrophoresis (page) and desalted using a c18 sep - ... |
Neoadjuvant chemotherapy actually takes an important place in treatment of operable breast cancer in the hope of improving conservative surgery rate of female patients . Neoadjuvant chemotherapy includes today on target therapies involving the research on expression of specific molecules by tumoral cells . In routine p... |
Understanding how and why vector - borne diseases like malaria remain a persistent problem despite being tools for diagnosis and treatment is essential for developing effective control measures for sub - saharan africa . Temperature is one of the key climatic variables that determine the range of malaria transmission a... |
The prevalence of pancreatic cystic neoplasms (pcns) is around 2.5%.1,2 pancreatic cysts are increasingly discovered probably because of the ubiquitous presence of multi - detector computed tomography (ct) scans and their increased use to evaluate patients with abdominal complaints . Endoscopic ultrasound (eus) plays a... |
Brucellosis is a zoonotic disease mostly transmitted to humans through consumption of unpasteurized dairy products and can lead to a systemic disease with any organ involvement . In this report, we describe a case of brucellosis - induced avascular necrosis of the hip . Brucellosis was diagnosed through serological tes... |
Since the framingham heart study first reported risk factors for atherosclerotic cardiovascular disease, numerous efforts have aimed at improving risk assessment in the asymptomatic population . Over time, these efforts have resulted in the introduction of framingham risk score (frs) and other biomarkers including the ... |
A sandwich or laminate technique is one of the methods proposed for composite resin restorations, which was introduced for the first time by mclean, et al . In 1985 . The basic idea behind this technique is to use two different restorative materials for a single restorative procedure so that the maximum physico - mecha... |
Planning, evaluating, and budget allocation for prevention programs are contingent upon estimating the size of their target groups . Population size estimation of the target groups in some context, such as hiv / aids, always entail numerous challenges in countries where such diseases are concentrated in specific sub - ... |
Benign prostatic hyperplasia (bph) is a highly prevalent disease affecting middle aged and elderly men (1). In the united states, bph is the most common benign tumor in men and is the most typically the disorder that reduces the quality of life (qol) in men, causing lower urinary tract symptoms (luts) (2). Bph could be... |
Primary retroperitoneal tumors (prts) of vascular origin are a diverse group of rare abdominal neoplasms, both benign and malignant . The most frequent malignant tumors are liposarcoma and leiomyosarcoma, while the most often found benign tumors are lipoma, leiomyoma and cavernous hemangioma [25]. Hemangiomas are a gro... |
The pathogenesis of gmd in pd patients is related to factors such as weight gain and insulin resistance evoked by peritoneal glucose load [13]. The periodical evaluation of pd patients for gmd is of clinical relevance and should be an element of the surveillance protocol . The gold standard method used for the diagnosi... |
Proteomics has emerged as a valuable tool for the identification of biomarkers associated with human disease including those resulting from very subtle changes in normal cell functions and signaling pathways . Proteomic technology has advanced to a state where thousands of proteins can be identified within complex samp... |
Type 2 diabetes mellitus (t2 dm) is considered a major epidemic of this century . It is estimated that its prevalence will increase worldwide from 371 million people in 2013 to 552 million people in 2030 . T2 dm is associated with accelerated progression of atherosclerosis, the major cause of vascular complications lea... |
Hidradenomas are benign cutaneous tumors of sweat gland origin, with the clear cell type constituting the most frequent histologic variety . Usually, they are diagnosed in the elderly population, the peak incidence being the fifth to sixth decade . We describe a young girl, in whom nodular hidradenoma developed at the ... |
The gothenburg osteoporosis and obesity determinants (good) study was initiated with the aim to determine both environmental and genetic factors involved in the regulation of fat mass as previously described (23). To be included in the good study, subjects had to be male, 18 to 20 years of age, and willing to participa... |
It is estimated that around 50% of the population has one or more sites with 1 mm or more of such root exposure . This prevalence rate increases to> 88% in individuals who are 65 years or older . Key factors in the treatment of gingival recession are to prevent the progressive marginal tissue recession and to facilitat... |
Ulcerative colitis (uc) is characterized by chronic and relapsing inflammation of the intestines, resulting in diarrhea, abdominal pain, and a variety of other symptoms (1), and impacts negatively on the quality of life . Huangqing - tang decoction, described by zhang zhongjing (150 to 219 a.d ., in chinese eastern han... |
Weekly creatinine clearance (wccr) and kt / v are well - known parameters reflecting dialysis dose and adequacy, and are applied to adjustment of the dialysis menu in each patient who undergoes peritoneal dialysis (pd). However, the limitations of these parameters in predicting survival and morbidity have been reported... |
Mesenchymal stem cells (mscs), also referred to as multipotent mesenchymal stromal cells, have been a focus of recent research, partially because they are an extraordinary model for investigating the biological mechanisms that allow a cellular population to generate diverse cell types and because they are a potential t... |
Carpal instability is broad category consisting of various patterns of injury, with dissociative type more common . A 13 -year -old boy presented at 6 months following a fall with restriction of wrist movements . Patient had sustained a closed distal one -third both bones fracture forearm fixed with k -wire, and volar ... |
Preeclampsia is a disorder affecting 5 to 10% of pregnancies and is clinically characterized by new - onset hypertension and proteinuria . Despite significant progress in our understanding of preeclampsia, there is a need for a reliable diagnostic biomarker for use in clinical practice . In the search for a biologicall... |
Illness is a challenge to our physical, psychological and spiritual wellbeing that has repercussions on our identity and our social context . In a pathogenetic approach, diagnostic tests are used to look for the underlying disease and treatments are aimed at removing it . A person is considered cured when the disease i... |
Macroautophagy (abbreviated as autophagy) is a genetically regulated and evolutionarily conserved pathway for the degradation of subcellular components [15]. This process involves the de novo formation of cytoplasmic double membrane - bound vacuoles termed autophagosomes, which sequester cytosolic cargo for delivery to... |
Koreich in 1981 first reported the case of a 22 year old man diagnosed as hodgkin lymphoma (hl) who developed hypothermia and hypotension during the course of his admission, which resolved only after initiation of chemotherapy . Systemic symptoms are present in a third of patients at presentation and among them fever i... |
Most conclusive evidences indicate that periodontal disease (pd) is not a conventional bacterial infection but is an inflammatory disease initiated by immune response against a group of microorganisms in susceptible hosts . The consequent uncontrolled inflammation causes destruction of attachment structures, being the ... |
Modafinil, a novel wake - promoting drug has gained immense popularity among psychiatrists in recent times . Now a days, its use is not limited to treat narcolepsy and other sleep wake disorders, but also in chronic fatigue syndrome, treatment resistant depression, attention deficit hyperactivity disorder and cocaine d... |
Childhood constipation is a common complaint accounting for 3% of visits to pediatricians and 10 - 25% of visits to pediatric gastroenterologist[13]. Commonly there is no underlying organic cause and the constipation is indentified as functional or idiopathic[4, 5]. Functional constipation is identified by rome iii cri... |
Recently, the use of magnetic nanoparticles (mnps) in medical applications (e.g. Magnetic fluid hyperthermia (mfh), magnetic drug delivery, magneto - mechanical actuation of cell surface receptors, magnetic gene transfection, and magnetic resonance imaging (mri) contrast improvement) has had an upward trend . The princ... |
It behaves highly aggressive and spreads widely throughout the skin, recurs locally, and metastasizes early . Standard treatment with resection and adjuvant radiotherapy results in local control in approximately 50% of patients at 1 year and median survival is approximately 8 months . Considerable evidence has implicat... |
Their contribution has gone beyond academic research the team of researchers in the national institute of mental health and neurosciences (nimhans), bengaluru, karnataka, india, has developed indigenous ect devices that have stood the test of time in terms of their use in clinical practice as well as in their contribut... |
The many genetic studies performed in recent years showed that genes such as interleukin 23 receptor (il23r) and il12b and tumor necrosis factor alpha (tnf) are closely associated with psoriasis and related diseases such as rheumatoid arthritis, psoriatic arthritis, and crohn's disease . Human leukocyte antigen c (hla ... |
A case showing sustained structural and functional responses 2 years after a single treatment with iluvien (0.2 g / day fluocinolone acetonide, fac) despite suboptimal responses to ranibizumab . A 68-year - old female patient with diabetic macular oedema (dme) from type 2 diabetes mellitus was first diagnosed in octobe... |
Patients were recruited from the epilepsy clinic at austin health, from the practices of investigators, and by referral for epilepsy genetics research from around australia and internationally . Informed consent was obtained from the patient or his or her parent or legal guardian . The study was approved by the institu... |
Previous studies have shown a close relationship between bone density and success of implant treatment [27]. Bone quality is determined by cortical bone thickness, the amount of trabeculae and mineralization and can be evaluated by bone density assessment . Several methods have been proposed for bone quality assessment... |
Damage of the cell membrane system, especially the plasma membrane, is one of the primary events in heavy metal toxic action in plants . Disruption of membrane integrity is thought to be an effect of a complex interaction between heavy metals and functional groups of membranes . It is well known that metal ions are eas... |
It is well known that they provide structural and metabolic support for neuronal networks, but a growing body of evidence indicates that they also play an active role in modulating neuronal activity . Astrocytes make close contact with perisynaptic regions, forming a functional structure called the " tripartite synapse... |
The online version of this article (doi:10.1007/s10953 - 014 - 0276-y) contains supplementary material, which is available to authorized users . In recent years, the deep desulfurization of diesel fuel has become the most studied process with different techniques (extraction, liquid liquid separation, oxidative desulfu... |
Higher carriage rates are seen in diabetics, intravenous drug users (ivdu), hiv and dialysis patients . All patients with s. aureus bacteremia should undergo transthoracic echocardiography (tte), since s. aureus bacteremia is associated with heart valve involvement in 25% of the cases . Nevertheless, tee has been shown... |
The use of nanomaterials in medicine involves the applications of nanoparticles and manufactured nanosystems to provide regeneration at the cellular and tissue levels . They encapsulate therapeutic agents and typically carry multiple targeting motifs such as hemostasis [1, 2]. For instance, ellis - behnke and coworkers... |
Falls are one of the leading injury - related accidents involving older adults whose muscular strength, proprioceptive sense, and bodily coordination are compromised with aging1 . The elderly lack obstacle negotiation capacity and are prone to trip over commonly encountered environmental barriers such as door sills, pa... |
A stroke is defined by the who as rapidly developing clinical signs of a focal (or global) disturbance of cerebral function, with symptoms lasting 24 h or longer or leading to death, with no apparent cause other than of vascular origin . Taking into consideration the cause, the mechanism and the character of morphologi... |
Erythromelalgia (em) is a rare disease characterized by painful swelling and erythema on the extremities [1, 2, 3]. The symptoms are often triggered by minor trauma, exercise, increased skin temperature, or heat exposure and often alleviated by cooling and elevation of the involved extremity . There are three distinct ... |
Discharging patient from intensive care unit (icu) is a difficult and complex process because icu nurses need to provide a lot of critical information to patients and delegate many heavy responsibilities to medical - surgical nurses . Moreover, more than one third of patients who are discharged form icu, develop seriou... |
By the turn of the century, it was clear that the vertical transmission of hiv to children could effectively be prevented with the appropriate use of short courses of antiretroviral therapy (art). In their landmark paper on the issue, de cock et al . Noted that few other aspects of hiv had, by that time, demonstrated r... |
The regulation of gene expression in the brain plays an important role in behavioral plasticity and decision making in response to external stimuli . Social insects such as honey bees represent good models to study the relationship between brain gene expression (i.e. Neurogenomics) and behavioral modulations,, . Insect... |
It is well known that genes can be silenced by antisense rna oligonucleotides called small interfering rna (sirna) (1,2). In order to design an efficient sirna sequence, empirical rules based on the features of the sirna sequence have been discovered, including, for example, low g / c content, lack of self - structure,... |
Stroke is a disease that causes sudden local neurological deficit symptoms due to a cerebrovascular accident1 . Stroke may decrease postural control and balance ability due to sensory disability, motor disturbance, muscular weakness, and asymmetric postures resulting from central nervous system damage2 . Reduced postur... |
A number of gases are produced endogenously in humans and have roles in the pathology of various diseases . Among these gases, nitric oxide (no) and carbon monoxide (co) have vital roles in the physiology of the body . Since the last decade, hydrogen sulfide (h2s) has captured the interest of scientists because of its ... |
Ischemic heart disease is rare during pregnancy, occurring in approximately one in 10,000 live births . The risk of myocardial infarction (mi) in pregnancy is reported from one per 37,500 to 6.2 per 100,000 deliveries.13 the diagnosis is by clinical findings, electrocardiogram (ecg), and measurement of the serum level ... |
Moderate or severe mitral regurgitation (mr) is the most frequent valve disease in the usa and the second most common form of valvular heart disease needing surgery in europe . Degenerative mitral valve disease (mvd) is the leading cause of organic mr in western countries . Its mechanism is primarily characterized by m... |
Surgical resections such as unilateral temporal lobectomy and amygdalo - hippo - campectomy have an established place in the management of carefully selected patients with refractory localisation - related epilepsy . Adverse cognitive sequelae of epilepsy surgery have been well - recognised since the seminal report of ... |
However, cardiac metastasis is diagnosed in less than 1% of patients with malignant melanoma because less than 10% of these patients present with cardiac symptoms.1 - 3) identification of cardiac metastasis from melanoma usually means that the patient is suffering systemic metastasis . Unlike typical cardiac metastasiz... |
Vitamin d deficiency (vdd) is defined as serum 25-hydroxy vitamin d (25ohd) levels <20 ng / ml . Vdd has been documented in more than 90% across all age groups and both sexes from india . Classical manifestations of vdd is described as rickets / osteomalacia, which manifest as bony deformity / pain, decreased bone mine... |
The penn diabetes heart study (pdhs) is an ongoing, cross - sectional study of individuals with type 2 diabetes (aged 3575 years) without clinical evidence of cvd (myocardial infarction, coronary revascularization or angiographic disease, positive stress test, clinical peripheral arterial disease or peripheral arterial... |
Collecting duct carcinoma (cdc) of the kidney is an unusual variant of renal cell carcinoma (rcc), accountings for less than 1% of all renal cancers . Cdc arises precisely from the principal cells lining distal collecting ducts of epithelium and distal renal tubules that originates from mesonephros . Considering that u... |
After approval by the institutional review board of the federal university of so paulo, brazil, 500 patients with dm from the diabetic foot outpatient clinic of orthopaedic department of the federal university of so paulo were enrolled in a prospective study to evaluate the results of minimally invasive surgery to trea... |
A 40-year - old woman, 169 cm, 57 kg, underwent laparoscopic right adrenalectomy due to an adrenal pheochromocytoma . A 7.5 fr 3-lumen catheter was inserted under ultrasonographic guidance (linear probe: ust-5546, 5 - 10 mhz, machine: prosound ssd-4400, aloka medical, co., ltd ., tokyo, japan) into the right internal j... |
Imbalance of muscles around the knee can cause changes in the alignment of the knee joint1 . Therefore, to prevent knee injuries in females, improved muscle balance around the knee during dynamic motions such as landing and balanced strengthening of lower limb muscles are necessary . Kim et al.1 found kinematic differe... |
Stemming from the seminal work by cannon and selye, stress is defined as " an alteration in the body's hormonal and neuronal secretions caused by the central nervous system in response to a perceived threat " and a stressor is defined as " a change in an organism's internal or external environment which is perceived by... |
Punctate inner choroidopathy (pic) is an idiopathic disorder representing one point on a spectrum of the multifocal choroiditides . The visual outcome is good unless complicated by submacular choroidal neovascularization (cnv), which may occur bilaterally . Treatment options of cnv in pic include argon laser photocoagu... |
Hemolysis, elevated liver enzymes, and low platelet count (hellp) syndrome is a severe manifestation of a hypertensive disorder of pregnancy called pre - eclampsia . It affects about 10% to 20% of patients with severe pre - eclampsia (0.5% to 0.9% of all pregnancies) and causes significant mortality and morbidity, whic... |
During the last few years, dual - source high - pitch imaging has become increasingly important in the daily routine of radiology departments . In dual - source computed tomography (ct) imaging two sources means that two x - ray tubes are in use at an angle of approximately 90 degrees to each other . After introduction... |
Inherited breast cancers are (pleiotropic) expressions of mutations in a number of distinct genes causing other cancers as well . To some extent, the biological function of the different genes is known, and to some extent the ways breast cancers are produced when this function is lacking, have been described . The canc... |
The past 15 years have seen major advances in our understanding of severity assessment in community - acquired pneumonia (cap). Prognostic tools have been promoted to guide all major management decisions in cap, including admission to the critical care unit . Several recent studies, including the study by renaud and co... |
Stroke is still a major cause of death and long - term disability worldwide and it is associated with significant clinical and socioeconomical problems . Despite the continuous efforts to develop the new pharmacological strategies, there is no effective neuroprotective therapy so far for ischemic stroke . Novel approac... |
Stress urinary incontinence (sui) is defined as the complaint of involuntary leakage on effort or exertion or on sneezing or coughing . Although sui is not a life - threatening condition surgical therapy is employed in patients who have severe degrees of sui or those patients in whom conservative or pharmacological tre... |
This causes misalignment between the sleep and wake propensities that are controlled by hypothalamic circadian pacemaker and results into shift work sleep disorder (swsd). The reported incidence of swsd in india is about 44.8% of night - shift workers and 35.8% of rotating workers . Swsd is characterized by persistent ... |
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