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Vaccination recommendations and programs are based on clinical trials performed in selected, healthy and mostly young populations . The data derived from these vaccine trials on safety, immunogenicity and efficacy are thus performed under ideal situations aiming to reflect the normal population distribution but certain...
In 1998, the incidence of typhoid / paratyphoid fever in china was 4.82 cases/100,000 population (60,146 cases reported); this measure has since decreased annually to 0.88/100,000 (11,890 cases) in 2012 (china information system for disease control and prevention, unpub . Data). Typhoid / paratyphoid fever cases in gui...
Stormwater catch basins are common sources of permanent or semipermanent standing water in urban and suburban residential areas and are considered to be important habitats for culex pipiens, a primary mosquito vector of west nile virus (wnv).15 because tens of thousands of these structures can exist within a mosquito c...
Specifically, it is characterized by sleep - related decreases (hypopneas) or pauses (apneas) in respiration . An obstructive apnea is defined as at least a 10-second interruption of oronasal airflow, corresponding to a complete obstruction of the upper airways despite continuous chest and abdominal movements, and is a...
The unique capabilities of the magnetic navigation system (mns) offer the possibility to perform ablations that would not be possible manually . We report the case of a retrograde transaortic approach to perform a pulmonary vein isolation (pvi). A 41-year - old female patient with highly symptomatic atrial fibrillation...
Type ii diabetes mellitus associated with obesity is becoming a worldwide epidemic and in most patients, the control of the disease is suboptimal even with maximum medical therapy currently available . The evidence for surgical intervention of dm is emerging and the international federation of diabetes (idf) has formal...
In 2010, four men employed at a seed supply company in chiba prefecture, japan, came to an occupational health physician of the company complaining of ocular irritation while working in a seed warehouse (warehouse a). To identify the cause of the problem and to take appropriate measures to resolve it, the company asked...
Enzymatic proteins can exhibit abnormal activity in a wide variety of diseases such as cancer and autoimmune disorders and, therefore, can be exploited for therapeutic and diagnostic purposes . This anomalous activity can help to increase the specificity and selectivity of drugs to diseased sites to reduce the harmful ...
Increased fatigability of skeletal muscles, characterized by difficulty in squatting and in performing repetitive motions, is commonly observed in both type i and type ii diabetes . Insulin - dependent diabetes mellitus (iddm) can also lead to ventilatory depression and decreased sensitivity to hypercapnia . Diaphragm ...
A 32-year - old female visited our hospital with a complaint of right knee pain . She had come three months ago for similar symptoms and had been diagnosed with ocd of the right knee based on clinical presentation and imaging studies obtained at that time . At the latest presentation, the pain increased in severity and...
The anticancer role of bacteria was recognized over a hundred years ago, when the american physician william coley began the first well - documented use of bacteria and their toxins to treat end - stage cancers . He developed a safe vaccine composed of killed bacteria species, which was used to successfully treat sarco...
Oral sub - mucous fibrosis (osmf) is a pre - neoplastic condition of the oral cavitythat causes significant loss of mouth function, because of reduced mouth opening. [15] osmf is predominantly seen in south - east asian countries with female: male ratio of 3:1 and in the age group of 4554 years . The condition is chara...
Stroke is the third most common cause of mortality and the primary cause of disabilities in the world . It is also an important cause of morbidity and high health care costs in industrialized countries . There is no reliable information about the prevalence or incidence of stroke in turkey . In industrialized countries...
Yersinia enterocolitica is an important zoonotic foodborne pathogen that can cause acute diarrhea, terminal ileitis, and mesenteric lymphadenitis in humans and animals [1, 2]. The isolates largely responsible for human yersiniosis in europe, japan, canada, and the usa belong to biotype 4/o:3 . The pig is considered the...
The lifetime risk of elderly undergoing at least one surgery for prolapse or incontinence by age of 80 years is 11% . Pelvic organ prolapse (pop) is rampant in a remote village called shillai, district sirmour, himachal pradesh . A project prolapse was introduced by the department of obstetrics and gynaecology, santpar...
Computed tomography (ct)-guided percutaneous fine needle aspiration biopsy (fnab) of lung lesions is currently one of the most commonly used techniques to determine the nature of lung lesions, such as nodules and tumors.1 because it is a simple, safe and reproducible technique with lower costs than a surgical biopsy, i...
The 5' adenosine monophosphate (amp)-activated protein kinase (ampk) is a heterotrimeric enzyme complex consisting of a catalytic subunit () and two regulatory subunits (and) 1 . Activation of ampk requires phosphorylation of threonine 172 (t172) in the catalytic () subunit by one of the three upstream kinases, liver k...
Sepsis which is characterized by a systemic inflammatory response syndrome (sirs) and the presence of an infection is one of the most serious complications in critically ill patients and it may finally lead to cell death and multi - organ dysfunction syndrome (mods). Sepsis and its subsequent complications are the most...
Study design - this is an observational descriptive study where epidemiological and clinical data from cases of cryptococcosis in children during the years of 1993 - 2010 were extracted from the national survey mentioned above . The national survey was designed in accordance with the guidelines given by the european co...
Viral meningoencephalitis leading to hydrocephalus is an extremely rare entity with only few documented cases, predominantly due to hsv-2 infection . Herpes simplex virus type 1 (hsv-1) infection of central nervous system present in the majority of the cases as encephalitis . An 11-year - old boy was presented to the e...
A 59-year - old caucasian male presented with complaints of chest pain for 2 h and racing heart . The pain started at rest, substernal, crushing in nature, constant, 7/10 in severity, non - exertional, not relieved by rest or nitroglycerin . With the pain not getting any better he has an established diagnosis of idiopa...
Among the several types of biocontrol agents, the pathogenic arthropod microorganisms such as the filamentous fungus metarhizium anisopliae deserve special attention . This fungus can infect a broad range of arachnid and insect hosts, from agricultural pests to vectors of human disease and recently the venomous spider ...
The restoration of endodontically treated teeth represents a unique challenge for clinicians because the retention of the final restoration is dependent on the use of the hollow interior of the root coronal to the endodontic filling using a properly fitted retention post . It has been suggested that retention posts sho...
At early stages of acupuncture research in japan, neural mechanisms were studied by many neurophysiologists . They demonstrated various neural connections in the central nervous system including ascending and descending spinal pathways and the involvement of endogenous opioids produced by low - frequency electro - acup...
Congenital aniridia is a rare condition (incidence between 1: 64000 and 1: 100000) that typically affects both eyes and is associated with pax6 gene mutations . This gene plays a role in the development of eye, mainly in the development of the cornea, iris, lens, drainage angle of the eye, and ciliary body [14]. Two - ...
The medical records of all children <16 years of age diagnosed with on over a 5-year period (20102015) were retrospectively reviewed . The clinical diagnosis of on was made on the basis of acute or subacute visual loss of 2 weeks or less, an afferent pupillary defect, color vision defect with or without optic nerve swe...
Pregnant rats were treated with 30 mg / kg of mtx on gd16, and fetal brains were examined histopathologically on gds 17, 18, 19 and 20 . Animals: all experiments were performed using female wistar imamichi rats, 910 weeks of age, 305.7 4.1 g (mean se) in weight, and obtained from the institute of animal reproduction (k...
Shoulder muscle strength is often studied with a particular focus on the relationship between swimming performance and muscle strength in front crawl swimming . In a previous study on the relationship between swimming performance and muscle strength, gola et al.1 reported a statistically significant correlation between...
Nevus of ota or oculodermal melanocytosis is a congenital hyperpigmentation of the facial skin in the distribution of the first and second divisions of the trigeminal nerve which is often associated with increased pigmentation of the various ocular structures.1 pigmentation may affect sclera, conjunctiva, cornea, iris,...
Plant material and cultivation - the individuals for field cultivation were obtained from selected seeds (a. absinthium var . Candial) and planted in ejea de los caballeros (zaragoza, spain) in 2008 . A detailed description of the field and eo analysis - plant material was distilled in an industrial stainless steel vp ...
Anemia is associated with reduced quality of life, significant morbidity, and increased mortality.1 partial correction of anemia, the maintenance of stable hemoglobin (hb) levels, and a reduced frequency of therapeutic interventions are common goals in anemia therapy.2,3 besides treatment of underlying diseases and com...
Pasteurella multocida is a facultative anaerobic, fermentative gram - negative coccobacillus found in the oropharynx of healthy animals, particularly cats, dogs, and pigs, as well as various wild animals . Cats and dogs have the highest carriage rates, at 70% to 90% and 20% to 50%, respectively . Human infections due t...
A male, 173 cm, 71 kg, at the age of 33 came to the emergency room with the chief complaint of pain at the right lower abdomen that had started one day before . The patient had been diagnosed with multiple sclerosis two years previously and has been receiving long - term care by another hospital . He used to take antic...
Patients attending out patient department (opd) of adult psychiatry were included in the study . After taking an informed consent, diagnosis of psychiatric illness was made according to the dsm - iv - tr criteria by either of the two psychiatrists (rg, md). The patients were broadly divided into two groups of those hav...
Microglial cells originate from myeloid cells of the hematopoietic lineage and are the resident immune cells of the central nervous system (cns). They are involved in the active immune defense by their ability to phagocytose invading bacteria and to release reactive oxygen species acting as microbicides . In the health...
2-oxoglutarate (2og)- and fe(ii)-dependent dioxygenases are widespread in eukaryotes and bacteria and catalyze a variety of reactions typically involving the oxidation of an organic substrate using a dioxygen molecule . One well - studied reaction catalyzed by such enzymes is the hydroxylation of proline and lysine sid...
Neuronal degeneration, i.e., neuronal cell death, underlies the pathology and malfunction of many different neurological diseases occurring in both animals and human beings . Progressive and selective neuronal cell death in the central nervous system (cns) and/or the peripheral nerve network has been profoundly implica...
Although most commonly due to cirrhosis and severe liver disease, ascites can be caused by a multitude of other conditions such as malignancy, heart failure, infections, pancreatic disease or dialysis . Whenever the etiology is not clear, the first step in the evaluation and management of ascites is diagnostic paracent...
May 25, 2004: an international team of historians, paleopathologists, anthropologists and archaeologists descended upon the church of san lorenzo, in florence, officially starting the medici project, a paleopathological and historico - medical study, whose aim is to reconstruct the habits, diseases and causes of death ...
Mucormycosis is an acute opportunistic infection usually seen in immunocompromised patients, particularly those with uncontrolled diabetes and leukemia12 . The disease is caused by a saprophytic fungus, mainly mucor or rhizopus, which is considered the most deadly and rapidly progressive form of fungal infection in hum...
When we move to music we feel the beat, this feeling can shape the sound we hear (2), and we detect the melody in music . Visual information is not necessary for this effect, as it likely reflects a strong, early - developing interaction between auditory and vestibular information in the human nervous system (3). Vesti...
Nearly all of this population use biomass and coal fuels for their day to day cooking and heating, the combustion of which is the dominant source of household air pollution (hap) in china and contributes significantly to the total burden of ill health in the chinese population . Particulate matter with an aerodynamic d...
We analyzed data from the cebu longitudinal health and nutrition survey, an ongoing study of a cohort of filipino women who gave birth between may 1, 1983, and april 30, 1984, in cebu, the philippines (www.cpc.unc.edu/projects/cebu) (6). Our study included data from children who were born and reached young adulthood du...
Giant cell tumor (gct) are solitary lesions, but 12% may be metachronously multicentric.1 pulmonary metastases occur in approximately 3% of patients due to its high vascularity and frequent treatment by curettage . The metastases are more frequent in cases of recurrent tumors and in enneking's stage iii lesion.15 the m...
Referrals are received by the cep statewide from clinicians seeking diagnostic testing for immunocompetent patients, including tb pcr testing when appropriate, who meet the cep case definition of encephalitis (1). Inclusion criteria for this report were a positive cerebrospinal fluid (csf) culture for mycobacterium tub...
Fluoride is an effective and safe method for prevention of dental caries, and is used for public health intervention in several countries through water fluoridation . Naf has been used to fluoridate water: as an industry standard for fluoridation and as an additive in toothpastes to prevent cavities . It has also been ...
Parkinson's disease (pd) is a progressive, neurodegenerative disorder characterised by the cardinal motor symptoms of resting tremor, rigidity, bradykinesia and postural instability (jankovic, 2008). At the time these symptoms first emerge, and the clinical diagnosis of pd can be made, approximately 70% of the dopamine...
Unintended or unplanned pregnancy poses a major economical, psychological, social, and/or religious challenge in women of reproductive age, especially in developing countries . It has been estimated that, of the 210 million pregnancies that occur annually worldwide, about 80 million (38%) are unplanned and 46 million (...
Dr greg hannon from cold spring harbour laboratory and cancer research uk cambridge institute was the keynote speaker at the conference . In the keynote speech, dr hannon described the development and use of modern rnai tools to probe the mechanism of metastatic progression . A big development has been the creation of ...
The clinical continuum of prostate cancer progression has successfully been interrupted by the advent of several newly approved agents, all of which have shown survival benefit and have unique mechanisms of action to modulate or diminish growth of prostate cancer . There has already been extensive discussion of novel a...
The prevalence of valvular heart disease increases with age and an estimated 13% of patients aged 75 years and over have heart valve disease . Indications for surgical intervention are well defined in guidelines and symptomatic severe heart valve disease is a class i recommendation ., valve surgery in the elderly is no...
Type i and type ii, based on histology, which differs in molecular as well as in clinical and histopathological profiles . Type ii is nonestrogen dependent, nonendometrioid, with higher grade histologies, more aggressive and carries an adverse prognosis . Although type ii cancers contribute only about 10% of ec inciden...
Mycophenolate mofetil (mmf) has been reported to be effective in the treatment of minimal change disease and lupus nephritis . However, there is no consensus on its use for minimal change disease especially in systemic lupus erythematosus (sle). A 24-year - old woman diagnosed with sle five years previously and maintai...
Although there is conclusive scientific evidence on health risks associated with exposure to shs, the health of a large proportion of children across the world is being adversely affected as a result of exposure to shs at home . An estimated 700 million children worldwide are exposed to second - hand tobacco smoke at h...
Russell silver syndrome (rss) is a heterogenous syndrome, characterized by intrauterine and postnatal growth retardation with relative macrocephaly (sparing of cranial growth), triangular face, bilateral clinodactyly, congenital body asymmetry and feeding difficulties [figures 1 and 2]. It is a rare genetic cause of sy...
A 43-year - old married housewife of high socioeconomic status presented to the psychiatry out - patient department with a 2 years history of morbid dread of pregnancy . She asked the physician about the complications of pregnancy . On hearing the dreaded complications like having a deformed fetus, change in body figur...
In the wide spectrum of congenital hemoglobin disorders, two entities have always attracted attention because of their severity and extensive geographic distribution, ie, beta thalassemia major and sickle cell disease (scd). In the present review, attention is focused on the latter disease, characterized by a qualitati...
Perfluorocarbon liquids (pfcls) are a mainstay of vitreoretinal surgery because of their high specific gravity, low viscosity, optical clarity and immiscibility in water, which permit surgical tissue manipulation . Pfcls are an adjunct in vitreoretinal surgery for complex retinal detachment repair as they displace subr...
Heart failure (hf) causes a significant economic burden, morbidity, and mortality . The primary cause of hf hospitalization (hfh) is volume overload which is treated using diuretic therapy . Further, ace - inhibitors and -blockers are known to reduce mortality in hf patients . Implantable medical devices, such as pacem...
Studies from radiology and echocardiography show that experts can accurately make a diagnosis using images viewed on handheld devices . Experts viewing radiological images on tablets perceive them as of comparable quality as when viewed on computer screens . Whether those favourable perceptions are specific to tablets ...
Ocular toxoplasmosis is the commonest cause of posterior uveitis and is usually the result of an acquired infection caused by the protozoan toxoplasma gondii [1, 2]. The most common manifestation of ocular toxoplasmosis is toxoplasma retinochoroiditis which is typically a unilateral, unifocal, large lesion (greater tha...
Although the overall 5-year survival rate is 40%, the survival rate drops markedly to 10% with increasing age and stage, largely because of treatment - resistant recurrence . Of the gynecological cancers, ovarian cancer has the highest recurrence rate, with over 60% recurring as therapeutically resistant after optimal ...
Arrhythmogenic right ventricular cardiomyopathy (arvc) is an important cause of ventricular arrhythmias and sudden cardiac death, especially in the young and in athletes (marcus et al ., 1982; thiene et al ., 1988; basso et al ., mutations in one or more genes encoding desmosomal proteins are found in 50% of patients (...
Adivasis (scheduled tribes [sts]), who are possibly india's oldest inhabitants, constitute 8.6% of the total population numbering 104.28 million (2011 census). Maharashtra's tribal population is about 10 million, which is 9.4% of the state population . There are three high - density clusters in the state - (a) northern...
We examined serum specimens from 376 persons that were collected at the university hospital graz, austria, from december 2001 to april 2002 . A total of 202 persons with domestic dogs, cats, or both (dogs n=77, cats n=106, dogs and cats n=19) were compared with 174 persons who had no domestic pet contact for at least 1...
Invasive cervical cancer is the second - most common cancer in women worldwide, but 80% of cases occur in developing countries.1 although readily detectable in its premalignant stage, cervical cancer remains the second most common cancer in nigeria2 and fifth in the united kingdom.2 among the female population in niger...
Signaling through the mitogen activated protein kinase (mapk) network affects virtually every major aspect of cell physiology and is among the most intensely studied cell signaling pathways in biology . Multiple mapk regulatory features related to signal strength, signal duration, compartmental localization, coordinati...
One model for the development of intestinal type gastric cancer is a prolonged progression from atrophic gastritis to intestinal metaplasia (i m) followed by dysplasia and ultimately cancer . Helicobacter pylori (h. pylori) infection has been shown to be an important risk factor for the development of gastric adenocarc...
Oral lichen planus (olp) is a relatively common inflammatory mucocutaneous disorder that frequently involves the oral mucosa . The exact etiology is uncertain, but the immunological system is believed to play a significant role in it . The age of onset is usually between 3 and 6 decade of life and it is commonly seen i...
The number of people living with alzheimer's disease or related dementia (adrd) is expected to more than double within the next 25 years, affecting over 1.1 million canadians and their families [1, 2]. Half of those with dementia live at home, and this proportion is increasing, especially amongst women . Furthermore, f...
Theacrine (1,3,7,9-tetramethyluric acid) is a methylurate, which is a class of purine alkaloids similar in structure to methylxanthines such as caffeine . Theacrine is often found as a methylated and oxidized metabolite of caffeine in methylxanthine - producing plants . The two prominent theacrine - containing foods in...
Symptomatic thoracic disc herniation is one of the rare degenerative diseases of the spine . Studies conducted on the general population revealed its incidence rate as approximately 1/1000000 patient in one year [13]. This rate applies to both women and men, and it is usually observed at ages 30 to 50 . The pathology u...
Cochlear implantations have become a routinely performed and successful surgical intervention in both adults and children . Cochlear implantation is associated with rather low complication rates, regardless of the individually chosen cochlear implant device [13]. Pediatric cochlear implants provide children with severe...
Aging is inextricably linked to the world around us and regularly pervades everyday life . Despite this, why organisms age remains a complex mystery that if understood could have profound implications for the quality of human health . While the physiological decline associated with old age is easily recognizable, the m...
Patients' time and costs during illness and health care treatment are relevant aspects to include in a complete analysis of the social costs of health interventions . Time and costs related to patients' travels from home to their health care providers are also relevant when the social implications of treatment options ...
Morphological integration of the cranium has become a dominant research paradigm in biological anthropology . While it began with the early work of weidenreich [1, 2] and the functional matrix model of moss [3, 4], morphological integration became a driving force in anthropological research through work on macaques and...
Split - hand / split - foot malformation (shfm) is also known as ectrodactyly . It is a malformation of the limb involving the central rays of the autopod and presenting with a deep median cleft of the hand and/or foot, aplasia / hypoplasia of the phalanges, metacarpals, and metatarsals . Shms expresses in two ways, on...
Abdominal aortic aneurysm (aaa) is a> 3 cm dilation found in the distal aorta . The ultimate complication of aaa is the rupture of the aneurysm, which is a life - threatening condition with an approximate overall mortality rate of at least 80% . Although different authors have demonstrated that the risk of rupture incr...
W ostatnich dekadach wprowadzono do uytku nowe, wysokiej jakoci zastawki stosowane w maych piercieniach aortalnych, ktre pozwalaj na uniknicie niedopasowania zastawki (patient prosthesis mismatch ppm). Celem pracy byo przeanalizowanie tendencji wystpujcych w operacjach wymiany mechanicznych zastawek aortalnych w pojedy...
Number of clinical trials (cts) conducted in iran has increased during the past few years (1, 2). Of total 10,550 projects conducted in medical research in 2011, 1027 clinical trial files have been reviewed in local and national ethics committees (3) and some 1147 cts have been registered in iranian registry of clinica...
A 58-year - old man was admitted with a 2-month history of headache and a 2-day history of ataxia . The patient had a previous history of a high - grade transitional cell cancer (tcc) of the bladder diagnosed earlier that year after presenting with dysuria, urinary frequency and renal failure with bilateral hydronephro...
Among the patients who underwent colonoscopic biopsy at kyung hee medical center and were diagnosed with colorectal tubular adenoma with any degree of dysplasia or colorectal cancer, a list of 50 patients was generated and their clinicopathological data were retrospectively collected . Patients were categorized into se...
Intracranial pial arteriovenous fistula (avf) is a rare cerebrovascular malformation, accounting for only 1.6% of all vascular malformation of the brain.9)10) pial avf was once regarded as a type of arteriovenous malformation (avm). However, current evidence suggests that the pathological characteristics and clinical p...
Hemagglutinin (ha) coding sequences for influenza a h3n2 viruses, former seasonal h1n1 viruses (preceding the 2009 pandemic), and influenza b virus lineages victoria (vic) and yamagata (yam) collected by the world health organization (who) global influenza surveillance and response network including the national instit...
Congenital pulmonary lymphangiectasia (cpl) is a rare primary developmental defect of the lung characterized by subpleural, interlobular, perivascular, and peribronchial lymphatic dilatation (1). Although the exact incidence of cpl is unknown, autopsy studies suggest that approximately 0.5%-1% of infants who are stillb...
India shines today with a whopping one billion army of its own, the dazzle, however, is marred by a myriad health problems . Urbanization, industrialization and technological advancement have established india as a force but the price the society is paying is a tremendous load of non - communicable diseases. (1) conseq...
37~40 mm in diameter, dense and velutinous, radially sulcae (8~16 sulcae) with several wrinkles, glaucous grey to pale olivaceous grey with 1~2 mm white mycelia at the margins, golden yellow in the center covered with clear or pale yellow droplets of exudates, soluble pigment not produced, margin entire, reverse yellow...
Systemic lupus erythematous (sle) is a complex debilitating and fatal autoimmune disease affecting between 1.4 and 2.0 million americans . Hormonal, infectious, and environmental factors have been implicated in the etiology of the disease [2, 3]. Although the precise etiology of sle remains elusive, the pathogenesis is...
Animal models of disease are important tools for biomedical researchers to understand human pathology, identify relevant drug targets, and develop new drug therapies . These models, generated through genetic or pharmacological manipulation, are employed in a wide range of fields including cancer biology, vascular biolo...
While many of today's cutting - edge alzheimer's disease (ad) research programs focus on understanding and targeting the molecular mechanisms underpinning this disease, the ultimate goal for researchers and clinicians is the treatment of dementia, preventing the cognitive decline and loss of quality of life that can be...
Uveitis causes glaucoma, cataract, and retinal damage, resulting in severe visual loss . Iris bombe is induced by formation of the posterior synechiae and pupillary block . Because intraocular pressure (iop) elevation during iris bombe is caused by angle closure, however, laser iridotomy has a high failure rate as a re...
From the earliest days of perutz crystal structures and the celebrated two - state ligation model of monod, changeux and wyman, hemoglobin (hb) has served as a paradigm for allosteric systems . Our understanding of the complex mechanism whereby the high - affinity r structure shifts to the low - affinity t structure co...
Any given time, most 16 - 18 year old and up to half of adults have acne . In 60% of teenagers, the condition is sufficiently severe for them to seek medical advice . In 7 - 17%, but since its introduction to the market, it has been alleged to be associated with a variety of adverse psychiatric effects, including depre...
Ranibizumab (lucentis, novartis pharma ag, basel, switzerland, and genentech inc ., south san francisco, ca, usa) is a humanised monoclonal antibody fab fragment, specifically designed for ocular use, that binds with high affinity to and inhibits multiple biologically active isoforms of vascular endothelial growth fact...
The cichorieae tribe (subfamily cichorioideae, family asteraceae) comprises about 70 genera and 1,500 species . The group is morphologically well characterized by the presence of latex and perfect flowers within the capitulum . Among the economically most important members of the tribe, lettuce (lactuca sativa l.), chi...
A 52-year - old female with no history of disease presented with a sudden bursting headache and transient loss of consciousness . An immediate ct scan showed a diffuse, thick sah in the basal cisterns and bilateral sylvian fissures (fig . Subsequent digital subtraction angiography (dsa) revealed a small hemispheric bul...
Chronic acalculous cholecystitis (cac) is a disorder characterized by biliary colic symptoms such as right upper quadrant abdominal pain, nausea and vomiting in the absence of calculi . It may also be known as biliary dyskinesia or functional gallbladder (gb) disease . Liver function tests are typically unremarkable, a...
Gestational trophoblastic neoplasms (gtns) represent a unique group of human tumors that develop as a semiallograft from fetus - derived tissues . Gtns were originally considered a homogeneous group of diseases arising from the neoplastic transformation of trophoblastic cells . However, recent clinicopathological studi...