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Ten independent and well - characterized ms case data sets were analyzed (table 1). The analysis included 1,079 white non - hispanic ms patients recruited from kaiser permanente medical care plan in the northern california region (kpnc). The following additional cases were included: 1,019 ms white non - hispanic patien... |
The steady - state level of core histone acetylation is modulated by a dynamic balance between histone acetyl transferases and histone deacetylases (hdacs). Histone acetylation results in relaxation of the chromatin structure, allowing access to transcription factors whereas deacetylation is associated with repressed t... |
Osteoporosis is a chronic condition characterized by decreased bone mass and deterioration of bone microarchitecture which compromises bone strength predisposing to fragility fractures . Current available treatments for osteoporosis are selective estrogen - receptor modulators, antiresorptive medications which include ... |
The aneurysms originating from carotid - opthalmic artery, supraclinoid internal carotid artery, and internal carotid artery bifurcation are more likely to present with symptoms of anterior visual pathway compression . A 65 years old, gentleman presented with headache of 3 months duration, and loss of vision in right e... |
Anti - glomerular basement membrane (anti - gbm) disease and anti - neutrophil cytoplasmic antibody (anca)-associated systemic vasculitis are each clinically associated with the development of rapidly progressive glomerulonephritis . Double positive, was seen in 5% to 14% of ancas - positive patients, and 21% to 38% of... |
We report 19 cases of confirmed autochthonous dengue fever treated at the national center for global health and medicine in tokyo, japan, during august 26september 22, 2014 (tables 1, 2; technical appendix table). Because the national center for global health and medicine is located close to the epicenter of this outbr... |
Musculoskeletal disorders (msds) are identified as work - related diseases from the time of ramazzini in the 18 century who described classical cases of such injuries in his book . They cause work - related disability in workers with notable financial outcomes due to direct and indirect (i.e., restricted or lost workin... |
Following initial surgery, the recurrence risk for differentiated thyroid cancer (dtc) is defined as low, intermediate, or high . Treatment with radioactive iodine (rai) is also used for remnant ablation and for patients with local and distant metastases . Administration of rai requires increased tsh to maximize rai up... |
With the remarkable growth of disability- and rehabilitation - related research in the last decade, it is imperative that we support the highest quality research possible . With cuts in research funding, rehabilitation research is now under a microscope like never before, and it is critical that we put our best foot fo... |
Jak ptk inhibitor cmp6 (2-tert - butyl-9-fluoro-3,6-dihydro-7hbenz[h]-imidaz[4,5-f]isoquin - oline-7-one) was from calbiochem (san diego, ca), and dexamethasone and insulin from sigma - aldrich (st louis, mo). Rabbit -phospho - akt - s473, -phospho - stat3-y705, -akt and -stat3 were from cell signaling (beverly, ma); -... |
Motor problems have been reported as common in persons with intellectual disabilities since intellectual disabilities are conditions that affect cognitive and motor functions1 . Intellectual disabilities negatively affect the life of a person with disability also by decreasing their motor function, which is manifested ... |
We used standard protocols to prepare the actin filaments and heavy meromyosin (hmm) motor proteins . Fluorescently labelled filaments stabilised with alexa fluor 488 phalloidin were used to visualise filaments with a fluorescence microscopy . Flow chambers built from nitrocellulose - coated coverslips were incubated w... |
Dabigatran (pradaxa, boehringer - ingelheim) is a direct thrombin inhibitor that is often substituted for warfarin because monitoring of anticoagulation is not required . In the re - ly study (randomized evaluation of long - term anticoagulation therapy), dabigatran was non - inferior to warfarin in reducing incidence ... |
12 - 005) by inje university busan paik hospital to review patients' charts, a retrospective study was initiated . Inclusion criteria were as follows: (1) posterior superior rotator cuff tear of the supraspinatus and infraspinatus tendons, but not the subscapularis tendon, (2) no concomitant biceps or acromioclavicular... |
The authors devised ides technique to replicate all the steps of open surgery with the idea to decrease the recurrences seen by other laparoscopic repair of male inguinal hernia published in the literature . Authors have operated 155 male patients by incise, dissect, excise and suture (ides) technique . Patients were k... |
One of the most important principles of shaping the root canal system is to maintain the original canal anatomy during a continuously tapering preparation . It is difficult to achieve this goal, especially in curved root canals because endodontic instruments are manufactured from straight metal blanks . This results in... |
Trigeminal neuralgia is a syndrome resulting from dysfunctional hyperactivity of the trigeminal nerve, and is defined as a sudden, usually unilateral, recurrent lancinating pain arising from one or more divisions of the nerve . The incidence of trigeminal neuralgia is 4.5 per 100 000 people . It is found more often in ... |
Locoregional staging for head and neck squamous cell carcinoma (hnscc) is performed using a combination of clinical examination, examination under anaesthetic and crosssectional imaging with computed tomography (ct) and/or magnetic resonance imaging (mri). Anatomical imaging is fundamentally limited for detection of ma... |
Antibiotic - resistant bacteria are implicated in an increasing amount of hospitalized patient infections worldwide . Among patients diagnosed with an infection, antibiotic resistance is associated with an increased length of hospital stay, health care costs, and patient morbidity, and mortality . Improved hand hygiene... |
Intra - articular glenoid fractures are extremely rare and may be associated with other injuries . Traditionally open reduction and internal fixation has been recommended in displaced intra - articular glenoid fractures . However open reduction is difficult and it may not be possible to address the associated intra - a... |
One of the most fascinating and challenging research frontiers in this field is the development of organic solar cells . In organic photovoltaic systems, exciton (electron hole pair) transfer followed by population transfer of electrons occurring via charge transfer (ct) states to a donor / acceptor (d / a) boundary is... |
They can be classified as resident (attached to a particular tissue), or migrating (free) cells . Resident macrophages adapt to the local environment in order to carry out specific functions, e.g. Control inflammation or restore damaged tissue . Despite heterogeneity resulting from the settlement of various organs pulm... |
Patients with chronic heart failure (chf) are characterized by systemic inflammation, as evidenced by raised circulating levels of several inflammatory cytokines such as tumor necrosis factor- (tnf-), interleukin- (il-) 1, and il-6 as well as chemokines, for example, monocyte chemoattractant peptide- (mcp-) 1, il-8, an... |
Periodontitis is a chronic inflammatory disease, which results in the destruction of periodontal connective tissue, alveolar bone resorption, and tooth loss.1,2 lipopolysaccharide (lps) leads to chronic inflammation resulting in disruption of the structural integrity of the periodontal ligament and progressive alveolar... |
The ongoing evolution of projects on structural genomics is making it increasingly important to collect, access and diagrammatically present information about the sequence, structure and function of any given macromolecule described in a protein data bank (pdb) file . The systematic comparison of such information among... |
The article from wu and colleagues investigates the question of using immunostimulation as a new approach in treating sepsis . The incidence of sepsis, and particularly severe sepsis, is expected to markedly increase in the next decade due to the aging population and more widespread use of therapies that compromise hos... |
The cornerstone of accurate tissue diagnosis is a pathologist viewing and correctly interpreting a microscopic image . A number of other important skills such as clinicopathological correlation are also important, but visual pattern recognition is the critical element . The gradual acquisition of pattern recognition sk... |
Written informed consent and agreement for publication were obtained from the patient . A 73-year - old woman (height 153 cm, weight 56 kg, asa ii) was admitted to our hospital as an emergency because of acute perforation of the small bowel with hemoperitoneum . Preoperative insertion of a central venous catheter was p... |
For a long time, gene regulatory network has been mainly focusing on protein coding genes 1 . However, the fact that about 90% of the human genome is transcribed at specific time points during the development yet only 1% is protein coding, suggests that abundant remaining gene sequences are still unknown 2 . Although t... |
A 41-year - old male patient presented with a complaint of deteriorating dyspnea for two months . At room air circumstances, arterial blood gas analysis was ph 7.39, paco2 35.7 mmhg, pao2 64.2 mmhg, hco3 -21.2 mmol / l, and sao2 92.5% . Chest x - ray showed a circumscribed mass shadow in the left lower lobe area and co... |
The fukushima nuclear accident (mar . 11, 2011) is regarded as one of the severest environmental disasters in the 21st century . The release of radionuclides into the environment in the course of this accident has only been exceeded by the chernobyl nuclear accident and the cumulative release from atmospheric nuclear e... |
Inflammation is classically characterized as heat (calor), pain (dolor), redness (rubor), and swelling (tumor). The short - term adaptive response of inflammation is crucial for integration of injury response and repair in cells and tissues . It has recently been shown that low - grade and chronic features of inflammat... |
Though reports of small bowel metastatic malignant melanoma are uncommon, their presentations as intussusception are rare . These metastases can present with almost any gastrointestinal symptom, which makes diagnosis difficult . Further, autopsy reports show much higher incidence of metastases to bowel than reported in... |
Conjugated microporous polymers (cmps) and related materials, such as covalent triazine - based frameworks (ctfs) and porous aromatic frameworks (pafs), are a fascinating class of materials that can, in some cases, combine microporosity with useful physical properties that arise from their electronic conjugation . Cmps... |
Na / h exchangers (nhes) are a class of membrane proteins involved in cellular ph control . During the past decades, several compounds belonging to the amiloride family have been developed as inhibitors of these membrane exchangers, for both basic research and pharmacological application purposes . The first nhe inhibi... |
Borderline ovarian tumors, as a distinct category were first recognized by taylor in 1929 who used terminologies like semi - malignant and borderline to describe them . Subsequent who classifications separated this group from carcinomas and called them as atypical proliferative ovarian tumors or borderline tumors . Ano... |
Pregnancy is characterized by a complex endocrine - metabolic adaptation process including impaired insulin sensitivity, increased -cell function, moderate elevation of blood glucose levels, particularly following the ingestion of a meal, and changes in the circulating levels of free fatty acids, triglycerides, cholest... |
Neisseria subflava is a family of the so - called commensal neisseria that is a part of the normal oral flora . Commensal neisseria is a rare cause of invasive diseases such as meningitis, endocarditis, bacteremia, ocular infections, pericarditis, empyema, peritonitis, septic arthritis, bursitis, and osteomyelitis (1).... |
Sex determination can vary widely within clades, with mechanisms as different as environmental and genetic determination occurring in related species, which indicates frequent de novo evolution of sex - determining mechanisms (bull 1983). Heteromorphic sex chromosomes such as the xy pair of mammals have arisen independ... |
However, only 40% of patients are eligible for radical surgical procedures (tis - t3 n0 - 1 m0) [1, 2]. The methods of surgical treatment for escc in the thoracic region and the cardia include radical esophagectomy with subsequent reconstruction of the gastrointestinal tract using fragments of the stomach, colon, or (s... |
Obesity and osteoporosis are two public health problems with an increasing prevalence and high impact on morbidity and mortality which, during the last two decades, have become major health threats worldwide.13 osteoporosis is a systemic skeletal disease characterized by low bone mineral density (bmd) and microarchitec... |
Micrornas (mirnas), a distinct class of ~22 nt single - stranded noncoding endogenous rnas, play pivotal roles in negatively regulating gene expression by targeting mrnas with an influence on multiple biological processes in plants and animals, including cell growth, differentiation, and apoptosis [13]. The primary tra... |
Bowel obstruction is a common surgical admission around the world usually resulting from post surgical adhesions or abdominal hernias . Conversely, small intestinal tumors, such as midgut carcinoids, are uncommon neoplasms and an infrequent cause of intestinal obstruction . Although the small bowel is the most common s... |
On may 15, 2012, a 67-year - old man came to mudanjiang forestry central hospital in mudanjiang, china, with an attached tick on his left shoulder . The feeding tick was detached in the outpatient department and subsequently identified as d. silvarum by an entomologist . Four days later, a painful erythematous rash dev... |
According to the (who), at least 220 million people or 2.8% of the population worldwide suffer from diabetes . Its incidence is increasing rapidly, and is estimated that by the year 2030, this number will almost double . The greatest increase in prevalence the increase in incidence of diabetes in developing countries f... |
The first successful treatment of a pediatric brain tumor was in 1879, when sir william macewen successfully removed a meningioma from a 14-year - old girl . Brain tumors are the most common form of solid tumors and the leading cause of death from solid tumors in children (seer program 1975- 1999). Advances in technolo... |
It causes ill - health among millions of people each year and ranks as the second leading cause of death from an infectious disease worldwide . In 2011, there were an estimated 8.7 million new cases of tb and 1.4 million deaths from tb (1). Urinary tract as initial infection is infrequent and associated extensive calci... |
Arteriovenous malformation (avm), a lesion thought to be congenital in origin, is a major cause of hemorrhagic stroke in children with 2% to 4% annual bleeding risk and a 17% to 90% lifetime risk of rebleeding . The risk of disability after bleeding is 30% to 35%, whereas the risk of mortality after bleeding is 5% to 1... |
The average age of stroke patients is 58.8 years old and stroke is the leading cause of a high mortality rate in people above 50 years old.13 the number of stroke patients is inclined to increase every year, not only among elderly people, but also young and productive people.4 the most common type of stroke is thrombot... |
A 62-year old male presented to the oncology center for evaluation of a painless, superficial nodular lesion over his left lower eyelid that had slowly grown over the course of approximately 18 months, to measure 4.0 2.0 cm . Patient gave history of a similar swelling at the same site which had appeared in july 2005 an... |
This transcriptome shotgun assembly project has been deposited at ddbj / embl / genbank under the accession gdkm00000000 . High yielding rice cultivars need high quantities of nitrogen which is usually supplied in the form of urea fertilizers . Rice cultivars show diversity in their nitrogen use efficiency which influe... |
Asthma is a common disease, but it has been questioned if it is one single disease, or a group of asthmatic diseases . Such different phenotypes of asthma may vary in response to treatment, in prognosis, in inflammatory patterns, and in susceptibility to environmental exposure . Identifying possible subphenotypes but a... |
It is not infrequently the case that the dose schedules proposed by the sponsors bear hardly any relationship to the pharmacology of the drug concerned . This applies not only to the neuroleptic drugs, but also to many other pharmacotherapeutic classes . When proposing a dose schedule, the factors most relevant are the... |
These trials were conducted in compliance with the declaration of helsinki, the international conference on harmonisation good clinical practice guidelines, the european union clinical trials directive, and local regulatory requirements . Approval for the study protocols and all amendments were obtained from columbia u... |
A 43-year - old man with a history of hypertrophic obstructive cardiomyopathy (hocm) was admitted to our hospital due to recently aggravated exertional dyspnea and palpitations . Transthoracic echocardiography revealed asymmetrical inter - ventricular septal hypertrophy with systolic anterior motion (sam) of the anteri... |
Patients with autoimmune diseases such as multiple sclerosis (ms) have greater susceptibility for development of another autoimmune disease,, . This issue is important, because occurrence of another condition, in particular a musculoskeletal disease in patients with previous neurologic lesions due to ms, increases the ... |
Parkinson's disease (pd) is the second most common neurodegenerative disease after alzheimer's disease . The prevalence of pd in japan has been estimated to be about 100 per 100,000 population . The exact etiology and pathogenesis of pd remain unknown at present [25]. The treatments for pd consist of antiparkinsonian d... |
Participation in sport activities promotes health, and reduces the risks of developing chronic diseases such as hypertension, heart disease, cancer and diabetes1; however, it also carries the risk of injury2 . Soft tissue, bone, ligament, tendon, and nerve injury can occur in athletes of all ages3 . Among children, the... |
Drug - induced liver injury (dili) is an important cause of liver injuries with significant morbidity and mortality [1, 2]. Accurate and early diagnosis is important but the diagnosis of dili is complicated and nonstandardized because of the difficulty in identification drug(s) causing liver injuries and lack of reliab... |
Recurrent aphthous stomatitis (ras) is a common disorder of the oral cavity which affects 5 - 66% of adult patients and 20% of the general population . The starting age seems to be between 10 to 19 years and decreases in severity and frequency with aging . Clinically, ras is characterized by one or several recurrent pa... |
Dentifrices have been a source of concern and subject of study for many professionals, since it is one of the main resources used in daily oral care by the population . Dentifrices have different components, such as detergents, fluoride, therapeutic ingredients, flavors, and abrasives . Among the abrasives, the most co... |
Over the last three decades, systemic lupus erythematosus (sle)-related mortality has decreased in all areas except cardiovascular disease (cvd).1 women with sle who are less than 40 years of age are at a 50-fold increased risk of myocardial infarction compared with control populations.2 this increase in risk cannot be... |
Nonpharmacological interventions to support children and adults with asthma include self - management education and support, information giving, behavioral change techniques, and efforts to enhance communication between the person with asthma and health care professionals . These diverse interventions have been provide... |
Proprioceptors consist of position (static) and movement (kinesthetic) receptors . In insects and crustaceans, chordotonal organs are the structures that provide that information to the cns . Not all chordotonal organs span a joint but they can still monitor joint movements due to their attachment on the apodemes (tend... |
At present, global environmental changes have been linked to the geographical distribution and dynamics of malaria . As with the simulations, the depictions of anthropogenic global and regional climate changes on health impact of malaria can alter malaria epidemiology landscape in receptive areas of southeast asia, sou... |
Paraganglioma - like dermal melanocytic tumor (pdmt) is a clinically and pathologically unique subtype of primary dermal melanocytic tumor . The term was based on their nested growth pattern in histology, which shows nests of clear to amphophilic oval cells separated by delicate fibrous strands . Only 10 cases have bee... |
As the average life span increases, people are becoming increasingly interested in quality of life, including dietary life . Dental implants are considered one of the most common and popular treatment options for edentulous patients, and there has been remarkable advancement in the techniques and materials in the field... |
Advanced gastric cancer is classified as the borrmann types based on the characteristic macroscopic morphology . Among them, borrmann type 4 gastric cancer is referred to as linitis plastica or scirrhous carcinoma, which has the characteristic of diffuse infiltration that occupies a large area of the stomach, serous in... |
Tuberculous lymphadenitis most commonly involves cervical group of lymph nodes and involvement of inguinal group of lymph nodes is uncommon . We report a case of isolated tuberculous lymphadenitis involving bilateral inguinal lymph nodes in a 42-year - old female . Primary or isolated inguinal tuberculous lymphadenitis... |
Worldwide annual incidence of traumatic brain injury (tbi), caused by falls, motor vehicle accidents, physical assaults, and sports injuries totals approximately 7 million people per year (song et al ., 2013). Data from the most extensive report to date (using a multistate population - based tbi surveillance system) in... |
The role of epicardial adipose tissue (eat) in the onset and progression of coronary artery disease (cad) is recognized, but the mechanisms and mediators promoting and linking eat dysfunctions and cad still need to be understood and described better . The receptor for advanced glycation end products (rage) is a multili... |
As a prospective randomized clinical trial, cirrhotic patients with ascites who were referred to al - zahra hospital were included in this study from january 2007 to january 2009 . All patients were of group c based on childpugh scoring system . In all patients, cirrhosis and ascites the study was approved by the local... |
The most important causes of death in western industrialized countries are cardio- and cerebrovascular diseases and malignancies . For instance, in germany in 2008, 68.6% of all women and 65.9% of all men died from these diseases . In contrast, the third most frequent cause of death are respiratory diseases which cause... |
Nitric oxide is a multifunctional, short - lived signaling molecule that plays an important role in a variety of regulatory pathways that are of significance to cellular survival, integrity maintenance, and the modulation of inflammatory responses to bacterial infection [13]. The physiological and pathophysiological im... |
Cutaneous schwannomas are benign tumors of schwann cells, commonly seen along the major peripheral nerves . Schwannomas, also known as neurilemmomas and anaxonal, intraneural schwann cell tumors are benign neoplasm of nerve sheath, originating from schwann cells . Schwannomas arise from the nerve sheath of large periph... |
Necrotizing soft tissue infections (nstis) are rare but highly lethal with a reported mortality rate of up to 76% . Prior reports have identified prompt treatment (defined by surgical debridement within 824 h after the patient arrives at the emergency department) as leading to decreased mortality rates . The general ag... |
In most protein - coding genes of eukaryotes the coding exons alternate with noncoding introns . The nuclear pre - mrna is a transcript of the whole gene, including the introns . However, before it is exported to the cytoplasm, the introns are removed through a process called pre - mrna splicing and the exons orderly j... |
Takotsubo cardiomyopathy (ttc) is an acute cardiac syndrome characterized by transient left ventricular dysfunction with wall motion abnormalities, most commonly in the form of apical ballooning . Takostsubo is a japanese octopus fishing trap, which best describes the characterstic left ventricular apical ballooning th... |
Telomerase is a specialized ribonucleoprotein complex that maintains the integrity and stability of eukaryotic chromosome ends [1 - 3]. Since conventional dna replication enzymes lack the ability to replicate telomere ends completely, telomere length homeostasis is crucial to avoid premature cellular senescence and age... |
The sit - to - stand (sts) test is a practical and valid measure of the balance ability of older adults . The sts movement is destabilizing because the body rapidly moves from a stable seated position to one with a less stable base of support and higher center of force (cof)1 . Healthy people aged 65 years or older exp... |
It is estimated that care for coronary artery disease (cad) results in annual direct and indirect costs of around 50 billion within the european union (1). A sizable proportion of this expenditure results from procedures used with the sole intention to confirm the diagnosis . Invasive coronary angiography (ica) is stil... |
A 71 year old asymptomatic woman came for an echocardiogram because of a left bundle branch block . A much dilated coronary sinus (cs) with an entering large vessel was found along with a mild left ventricular systolic dysfunction . Cardiac magnetic resonance (cmr) showed a persistent left superior vena cava (plsvc), a... |
The prevalence of type 2 diabetes mellitus has increased dramatically worldwide, mainly because of changes in lifestyle, such as decreasing exercise and increasing high - fat diets . Obesity is the hallmark of the metabolic syndrome and represents a major global health problem that is frequently associated with the dev... |
Ankle joints have a complicated anatomical and mechanical structure, and can have develop, which are among the most frequent injuries during normal physical activities1,2,3 . Ankle trauma can be categorized as acute or chronic; conservative treatment with rehabilitation training is crucial because chronic lateral insta... |
Premenstrual syndrome (pms) is one of the most common difficulties in women at their reproductive age . Pms is known as the recurrent mood and physical symptoms which is generally in the luteal phase, and it remits in the follicular phase of the menstrual cycle.2, 3 there is a high incidence of pms; about 80% of women ... |
In the human gastrointestinal tract, there are up to 10 bacterial cells per gram of colonic content, and gut microflora is constituted by 400 - 1,000 species of bacteria.1,2 balanced intestinal microflora plays a direct impact on maintaining the gut homeostasis such as regulating bowel motility, modulating intestinal p... |
Although drug - eluting stents (des) have significantly reduced the rate of restenosis by effectively suppressing neointimal growth compared with that of bare metal stents, complications such as in - stent restenosis and stent thrombosis still occur . The incidence of stent fracture is 1 - 8%.1) most stent fractures ar... |
The extraction of mesioangular - impacted third molars may cause multiple periodontal defects at the distal root of the second molar . These complications are even more frequent in older patients and when there are preoperative periodontal defects on the distal surface of the second molar before extraction of the impac... |
Although many researchers have investigated the pathogenesis of pdac, thus far, the crucial evidence pointing to causative inflammation and/or infection for pdac has not yet been uncovered as it has in the case of hepatocellular carcinoma, gastric cancer, and cervical cancer . The pathogenesis of pdac might be similar ... |
Tuberculosis (tb) is a major global health problem, and can be a multisystemic disease . Tuberculosis of the ribs usually presents with rib destruction and soft tissue mass of the chest wall, which is called tubercular abscess of the chest wall (tacw) or cold abscess of the chest wall . The isolated involvement of cari... |
Insulin resistance in muscle and liver and -cell failure represent the core pathophysiologic defects in type 2 diabetes mellitus (t2 dm). Most patients with t2 dm also develop serious complications because of chronic hyperglycemia, such as nephropathy, retinopathy, neuropathy, and cardiovascular diseases, like coronary... |
Cystic fibrosis is the most common recessive disease in caucasians with a prevalence of about 1: 2500 . Cystic fibrosis is characterized by progressive lung destruction due to chronic neutrophilic airway inflammation and bacterial infection . Most of the morbidity and mortality of cystic fibrosis patients results from ... |
The generation of action potentials in excitable cells requires that the magnitude of na current on the surface membrane be large enough to overcome the electrical shunting current through other membrane conductance . Multiple action potentials raise extracellular k concentrations, leading to a depolarization of membra... |
Hollow and concave nanocrystals (ncs) are an interesting class of materials with potential applications in catalysis, energy storage, plasmonics, and medicine . They can be synthesized by implementing the kirkendall effect at the nanoscale, by combining the kirkendall effect with anion exchange, via ostwald ripening, b... |
In the early stages of introducing new health interventions such as novel products or services, there is often considerable uncertainty around their potential uptake, impact and costeffectiveness . In such cases, mathematical modelling studies are frequently used to decide whether these new interventions could be coste... |
Paget s disease of bone (pdb) is a common skeletal disorder characterized by osteoclast activation, which provokes increased but disorganized bone turnover, leading to pathological fractures, bone deformity, and bone pain . The disease has a strong genetic component, but the genes responsible have not been fully charac... |
Cattle and pigs are globally important for the production of animal protein . Since their genomes are evolutionarily separated by about 60 million years, comparative information about the organization and expression of their genomes will accelerate our understanding of the physiology of these species . Recent data from... |
We aim to describe a mechanism of vision loss following vitrectomy surgery with retrobulbar block (rbb) associated with severe vascular stasis of the optic nerve and macula in order to improve safety of local anesthesia for ophthalmic surgery . We report three cases of patients who underwent pars plana vitrectomy (ppv)... |
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