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Video 1left paraaortic, inframesenteric lymphadenectomy supported by icg labelling in cervical cancer.video 1 left paraaortic, inframesenteric lymphadenectomy supported by icg labelling in cervical cancer. |
The atlantic codex (ac) is the largest collection of drawings and writings by leonardo da vinci, including 1,119 pages collected in 12 volumes, and it is currently preserved at the biblioteca ambrosiana in milan . The sheets (64.5 43.5 cm) were assembled in no particular order and cover a long period of leonardo studie... |
Uterine synechiae or asherman's syndrome is a condition which can cause infertility, menstrual abnormalities, and recurrent pregnancy losses that occurs due to a partial or complete closure of the uterine cavity and/or the cervical canal (1). Moreover, this obliteration may be a direct outcome of surgical endometrial l... |
Multiple sclerosis (ms) is a progressive disease of the central nervous system in which communication between the brain and other parts of the body is disrupted . Its effects can range from relatively benign in most cases to somewhat disabling and then to devastating for some people . During an ms attack, inflammation ... |
Hepatic portal venous gas (hpvg) was first described in 1955 in an infant with fatal necrotizing enterocolitis, and subsequently reported in adults . It is a rare condition with numerous etiologies, including bowel infarction, necrotizing enterocolitis, closed loop obstructions, acute hemorrhagic pancreatitis, granulom... |
Among the many causes of dyspnea associated with ph in a patient with history of cancer, paraneoplastic thrombotic pe is the most common aetiology and must be considered in priority . But tumour cells can metastasize in the pulmonary vasculature in three mechanisms: occlusion of the small pulmonary arteries, pulmonary ... |
Nonalcoholic fatty liver disease (nafld) is among the most common causes of chronic liver disease worldwide . The prevalence of nafld in the general population of western countries is 2030% . Within the spectrum of nafld, only nonalcoholic steatohepatitis (nash) most patients with nafld have risk factors such as insuli... |
Early in the history of ct scanning, specialized windowing was found to be beneficial for the analysis of bone lesions . Becker et al 1 demonstrated in 1978 that more calvarial metastases were detected with bone windows than with brain windows . The human eye distinguishes a limited number of shades of grey and the wid... |
The automated gravitational vario flow system was constructed in order to reduce the risk of fluid intravasation while using gravity for uterine distention during continuous flow hysteroscopic procedures . It provides linear regulation, definition and measurement of intrauterine pressure by simply pressing the pedal an... |
Msos is a formatted text - messaging system that enables communications between healthcare facility workers and ministry of health managers and uses a web - based portal to monitor disease notifications and response actions taken by health managers (figure 1; online technical appendix, http://wwwnc.cdc.gov/eid/article/... |
The onset of labour is associated with changes in gene expression in the myometrium consistent with activation of inflammatory mediators and leukocyte chemotaxis [1, 2]. The uterine expression of the chemokine il8 increases dramatically with the onset of term and preterm labour [3, 4] and is thought to promote cervical... |
There is a high comorbidity of schizophrenia and obsessive - compulsory disorder (ocd) associated with more severe symptoms . We report about a 48-old women treated for depression which developed successively psychotic symptoms (ideas of reference, psychotic worries), negative symptoms (blunted affect, impoverished thi... |
Immunotherapy is a new class of cancer treatment that works to harness the innate powers of the immune system to fight cancer . Major conceptual and technical advances in immunology have led to a new understanding of cellular and molecular interplays between the immune system and a tumor over the past decades [1 - 3]. ... |
Distance measurements by pulsed dipolar electron paramagnetic resonance (epr) spectroscopy are a standard tool for generating distance constraints for structural modelling . The pulsed electron electron double resonance (peldor or deer for double electron electron resonance) developments in commercial hardware, standar... |
Since 1960s several researches have been performed to observe the effect of meditation in practitioners versus nonpractitioners . It is a meditation in which one obtains mastery over one's unruly mind through objective observation of one's own natural and normal breath . In pali literature, it is known as this practice... |
Solid oxide fuel cells (sofcs) are very promising as a source for sustainable and renewable power generation . Despite the efforts of researchers worldwide, a more detailed, atomic scale understanding of the elementary, interface controlled processes of sofcs is necessary to tailor their performance and lifetime . Sofc... |
Following the first report of 2009 pandemic influenza a (h1n1; hereafter referred to h1n1 2009) in april 2009, the infection became a pandemic . The drugs of choice for the treatment and prophylaxis of h1n1 2009 are neuraminidase inhibitors including oseltamivir (tamiflu [roche]) and zanamivir (relenza [glaxosmithkline... |
Obstructive sleep apnea syndrome (osas) is a highly prevalent disorder affecting about 4% of adults, and is associated with repetitive episodes of transient oxygen desaturation during sleep . Osas is an independent risk factor for a number of cardiovascular diseases [24]. Although uppp expands pharyngeal cavity and imp... |
Patients with behet's disease often need intraocular surgeries for the treatment of secondary cataract or glaucoma . This study aims to report the clinical course before and after the intraocular surgeries of 5 patients who were systematically treated with infliximab . Seven eyes of 5 male patients with behet's disease... |
Queen elizabeth hospital in blantyre, malawi, is a teaching hospital offering free services to a population of approximately 1 million . From 2006 until 2009, 3 prospective adult (age 16 years) meningitis studies were conducted at the hospital; a randomized controlled trial of adjunctive oral glycerol in bacterial meni... |
Although it is increasingly being considered the standard of care in such patients, not all patients receive tavi but instead continue medical therapy (mt). Historically, the treatment decision heavily depended upon the assessment of risk of valve replacement by using the logistic euroscore (les) or society of thoracic... |
The genus passiflora comprises about 500 species which are mostly woody vines that present a huge diversity in flower shape, colors and sizes . Consequently it is a good model for studying plant - pollinator interactions and co - evolution, since it displays all kinds of pollination syndromes . Although this diversity ... |
Early prenatal diagnosis of congenital anomalies often approaches the limits of ultrasonography in the first trimester of pregnancy . Further evaluation can be performed by embryofetoscopy which provides direct visualization of the embryo and fetus . With the development of small fiberoptic endoscopes, transabdominal e... |
Epidemiological studies indicate that more than 70% of diabetes mellitus (dm) patients die of cardiovascular disease (cvd); this number is 2 - 3 times higher than the mortality of cvd in the nondiabetic population . The prevention of cardiovascular events is a very important goal in the treatment of dm . Diabetic cardi... |
Primary cancer of the male urethra cancer occurs rarely . It entails less than 1% of all cancers of the urogenital system in men . More rarely it develops in the distal part of the urethra . In about 80% of the patients, it is a squamous cell carcinoma (scc) and in 15% it is a transitional cell carcinoma (tcc). The fir... |
The defects of the soft palate are difficult to reconstruct because of their complicated anatomy and causing velopharyngeal incompetence for speech and swallowing function . Many reconstruction techniques have been described to improve postoperative function after oropharyngeal resection including soft palate, but the ... |
Breast cancer (bc) originates from the epithelial cells of the breast tissue that line the terminal duct lobular unit . Bc is the most common cancer type that affects world population . More than 180,000 new cases of bc were diagnosed in 2008 in the united states alone . Over bc in women is the most commonly diagnosed ... |
Apical periodontitis is an infection of the area around the root of a tooth, usually caused by bacteria . Although bacterial infection can be substantially reduced by standard intracanal procedures such as intracanal medication and root canal treatment, it is very difficult to render the root canal free of bacteria . T... |
Although levetiracetam (lev) is a relatively well - tolerated anti - epileptic drug (aed) that is used to control partial and generalized seizures, an encephalopathy resulting from lev administration has been previously reported.1,2 encephalopathy induced by aed has been observed in patients with vpa, however, it is de... |
Pruritus in pregnancy has always been challenging to the treating physician both in diagnosis and treatment . Pruritus occurs due to various causes, and it can occur any time during pregnancy . Causes for pruritus in pregnancy are numerous ranging from specific dermatoses of pregnancy to various dermatological conditio... |
Kaposi's varicelliform eruption is a disseminated cutaneous infection usually caused by the herpes simplex virus (hsv). It predominantly occurs in patients with pre - existing active dermatosis and is characterized by disseminated vesiculopustules and erosions . It is common in patients with atopic dermatitis and rarel... |
The purpose of evidence - based medicine is to apply the best scientific evidence to clinical decision - making . In order to guide doctors and health professionals, the royal colleges publish guidelines and recommendations for good clinical practice within their respective specialties . Critics (wright 2007) say that ... |
Intestinal malrotation is a congenital abnormal position of the bowel within the peritoneal cavity . In cases of midgut volvulus, it is critical to make a diagnosis and to intervene immediately to avoid the potentially life - threatening consequence of intestinal necrosis, which in severe cases may lead to short bowel ... |
The first two micrornas (mirnas) discovered, lin-4 and let-7 from caenorhabditis elegans, were described in 1993 and 2000, respectively . These two mirnas, which are both 21 nucleotides long, were found to be endogenous regulators of genes involved in developmental timing [1, 2]. Since then, hundreds of mirnas have bee... |
Tartrazine (ta) and sunset yellow (sy) are synthetic food colors used most extensively as food additives, to improve the appearance, color, and texture of foods . When added in excess, however, these synthetic food colors can be pathogenic . To ensure food safety, the chinese government has imposed rigorous standards o... |
Methicillin resistant staphylococcus aureus (mrsa) was initially reported as a nosocomial pathogen responsible for adult infections . Ca - mrsa has been recognized as a pathogen in adults and children without traditional risk factors for mrsa acquisition . Children colonized with mrsa are potential reservoirs for the s... |
The world health organisation (who) recommends opioids for the relief of moderate to severe cancer pain . Oxycodone is metabolised in the liver mainly by cyp3a4 to noroxycodone, but also by cyp2d6 to oxymorphone, and via 6-keto reduction to - and -oxycodol . Cyp3a4 and cyp2d6 belong to the cytochrome p450 system, the p... |
Helicobacter pylori is a gram - negative, spiral, catalase - positive, and urease - positive bacillus which contributes to a wide range of gastrointestinal (gi) and extra - gi diseases (1, 2). H. pylori has gained particular importance nowadays since it has infected about 50% of the world s population . However, its pr... |
Metabolic syndrome (ms) is characterized by the presence of insulin resistance, low - degree inflammation, dysglycemia, low plasma high - density lipoprotein cholesterol (hdl - c), increased triglycerides (tg), elevated blood pressure, and abdominal obesity . Ms has been associated with an increased risk of type 2 diab... |
The online version of this article (doi:10.1007/s40119 - 014 - 0034 - 7) contains supplementary material, which is available to authorized users . Patients undergoing structural and congenital heart interventions usually require large - sized sheath insertion into the femoral arteries . Hence, active management of the ... |
The compound muscle action potential (cmap) scan is a noninvasive diagnosis technique for neurodegenerative pathologies, such as amyotrophic lateral sclerosis (als). It allows a quick analysis of the muscle action potentials in response to motor nerve stimulation, by electrical stimulation applied on the surface of the... |
Its effects are mediated principally through triiodothyronine (t3), which acts as a ligand for the th receptors (trs) 1, 2 and 1 [harvey and williams, 2002; yen, 2001]. In the classical model of genes positively regulated by th, the tr first binds as a heterodimer or homodimer on th response elements (tre) located in t... |
The principle goal of sedation for eye surgery is to prepare the patients to stay calm during retrobulbar injection and surgery . Both insufficient sedation and deep sedation may lead to sudden movements by patients, which may potentially result in harmful complications during open eye surgery . Cognitive impairment ha... |
This risk must also be considered for patients who are using these medications for off - label inflammatory skin conditions . We present the first patient with treatment - refractory sweet's syndrome who developed disseminated nocardia brasilienses whilst on methylprednisolone and infliximab . A 62-year - old white mal... |
Atrial fibrillation is the most common heart arrhythmia affecting around 2.2 million people in the usa . Depending on the ablation device used, it is carried out using either electroanatomic mapping systems, an x - ray guided approach, or a combination of both . X - ray guidance is, for example, required if a cryoballo... |
Inguinal herniorrhaphy is one of the most common elective procedures performed worldwide . In the united states, an estimated 800,000 inguinal hernia repairs are performed each year, accounting for 10% to 15% of all surgical procedures . However, there continues to remain controversy surrounding the optimal surgical ma... |
Surgical resection of lm is the only potentially curative modality, but it is possible in less than 20 percent of patients . Majority of patients are not suitable for surgical resection due to various clinical and technical reasons . For such patients, various non - surgical options are three dimensional conformal radi... |
1 . An autoimmune mechanism has been implicated in the pathogenesis of vitiligo in most cases . 2 . Histamine mediates some actions through various interleukin pathways and elevated levels of serum soluble il-2 receptor, il6, and il- 8 has been reported in vitiligo patients . Vitiligo is an acquired, idiopathic disorde... |
The course of the three major nerves crossing the elbow is quite consistent, yet in some instances variations are encountered particularly if the elbow has deformed following previous episode of fracture and surgery . We present here a case of entrapment of radial nerve in the bone without any signs of nerve palsy resu... |
On page 24 of this issue of critical care, meduri introduces a new layer of complexity to our understanding of the inflammatory response in acute respiratory distress syndrome (ards). He postulates that cytokines secreted by the host during ards may favor the growth of some strains of bacteria and consequently explain ... |
A total of 34 molecules with dpp iv inhibitory activity were selected for hqsar analysis and chemical structure constructed on the sketch module of sybyl x2.0 software . The hqsar studies require the minimization of structure, calculation of the force field and charges . The energy minimization and charge calculation d... |
Initial research on informality viewed it as economic practice beyond the reach of the state, connected to the income generation activities of the urban sub - proletariat seek[ing] informal means of increasing their incomes (hart, 1973: 67). Subsequent scholarship broadened the concept to include unregulated land - use... |
Cementodentinal junction (cdj) is the area at the interface between cementum and dentin . The attachment of cementum to dentin is said to be due to the presence of adhesive proteoglycans primarily and secondarily due to fiber intermingling fortified by mineralization . Studies on cdj have proved that this junctional ti... |
Computer simulations have determined that or utilization efficiency of 85 to 90% provides the best cost benefit ratio with the lowest patient delays or staff overtime.1 this efficiency is calculated by adding the anesthesia induction and recovery time and the surgical time and the interpatient change over time, and div... |
Endovascular embolization has become a common method for the treatment of intracranial aneurysms in many centers of the usa and europe [1, 2]. However, coiled aneurysms present a significant rate of recanalization, which occurs in approximately 20% of patients [3, 4]. Due to the possibility of recanalization and the av... |
Endophytic actinobacteria have a capacity to produce numerous secondary metabolites with a mass of biological activity, such as antibiotics, antitumor and anti - infection agents, plant growth promoters and enzymes, and may promote plant establishment under adverse environmental stresses . Introducing such bacterial st... |
Diabetic nephropathy (dn) is the leading cause of end - stage renal disease . Mesangial cell proliferation, excessive extracellular matrix (ecm) proteins accumulation, basement membrane thickening, mesangial expansion, and other mesangial region lesions are involved in the renal pathological process, which ultimately l... |
Peritoneal dialysis (pd) is a well - established means of renal replacement therapy . A tenckhoff catheter is electively inserted into the peritoneal cavity before pd starts . After a healing period of at least two weeks 500 ml volumes are used for the first two days of training and titrated upwards, based on body surf... |
We have reported a 78 year old man with complaint of abdominal pain and vomiting . In patients preoperative evaluation for surgical management of an intra - abdominal mass, a large intracardiac mass has found incidentally during the echocardiography . Pathologic biopsy of right atrial mass that has removed by open hear... |
It was recently revealed that one quarter of paediatric intensive care beds in holland are closed and that many critically ill children have to be transferred to receive care . Problems organizing paediatric intensive care exist in most health care systems . If we are to avoid crises such as this then we have to solve ... |
Lead is an element that expanded on the environment as a result of human activity during the past thousands of years . Lead poisoning is due to increased levels of lead in the body (1) and hasnt specific signs or symptoms . Lead is found in a variety of organs including the heart, bones, intestines, kidneys and nervous... |
The index patient, a 26-year - old woman, was admitted to the infectious disease ward of a university hospital with a temperature of 40c and myalgias 3 days after she returned from a 3-week trip to cambodia and thailand . She was discharged in good condition after the fever subsided . On the day of admission of the ind... |
Dental identification can be used for identifying the deceased or the assailant in a crime scene or for identification of victims of a mass disaster . In the asia pacific region, because of its wide range of variations in topography and climatic conditions, india is a disaster prone country with an average of eight maj... |
Ctc are usually detected in the peripheral circulation, but we can find ctc in other body fluids like the cerebrospinal fluids or the urines . The limitations to discover the ctc in these fluids are the same than in the blood circulation . However, it is possible to extract a relatively big amount of blood without harm... |
The american dental association (ada) defines dental amalgam as an alloy composed of mercury, silver, tin, and copper along with other metallic elements added to improve physical and mechanical properties . Dental amalgam has been an accepted part of dental treatment for more than 170 years [25]. Mackert and wahl (2004... |
Endodontic treatment aims to disinfect and to shape the root canals in order to make easy the irrigation procedures and the placement of root canal dressing of filling material . The preservation of the radicular anatomy is one of the most important concerns during root canal preparation . Some enlargement techniques h... |
Deep venous thrombosis (dvt) is a complication well - known to be associated with nephrotic syndrome . In patients with nephrotic syndrome, dvt is reported to be observed mostly in the lower extremities, renal veins, and pulmonary arteries [1, 2, 3]. However, there are no reports of dvt developing in the upper extremit... |
Major depressive disorder (mdd) constitutes the first leading cause of years lived with disability, and its incidence is on the rise globally . Yet, until recently, little was known about its pathogenesis, as these conditions are not associated with relevant brain alterations or clear animal models for spontaneous recu... |
Odontogenic cysts are caused from odontogenic epithelium in the process of dental apparatus development and can be originated from one part of dental organ . Inflammatory cysts have an inflammatory reason but the cause of the developmental type is unknown . Odontogenic cysts can cause bone inflation, teeth mobility, fi... |
Photocuring is the key technique for the preparation of films and coatings as it offers a broad and economic application spectrum for industry . During the curing process it absorbs energy from a photon either in a direct or an indirect process, transferring it into chemical energy . After the excitation process a reac... |
Samples of vegetation affected by the typical fusarium wilt were collected from several areas by cutting the infected part of the stem from the zucchini plants . The infected tissues were surface - sterilized with a 1% naocl solution for 1min and rinsed 2~3 times with sterilized distilled water . After drying, we cultu... |
The gastrointestinal tract is the most common site of extranodal non - hodgkin's lymphoma (nhl) and the small bowel is considered the most commonly affected part of the gastrointestinal tract . Lymphoma of the hepatobiliary system usually presents as secondary manifestation of systemic malignant lymphoma . However, pri... |
Since the discovery of transposable elements (tes) in corn, dna sequencing has revealed that genomes of eukaryotic organisms are largely comprised of evolutionarily significant tes responsible for creation of considerable genetic diversity . The movement of transposable elements is either autonomous or dependent on oth... |
Acne inversa (formerly hidradenitis suppurativa) is a rare chronic and debilitating inflammatory skin disease . It forms inflammatory nodules, abscesses, fistulas, and scars in the apocrine - gland - bearing regions [1, 2]. The disease usually occurs after puberty and starts in the areas, where there is skin - to - ski... |
The tiny protrusions emerging from dendrites known as dendritic spines are the primary subcellular locations of excitatory synapses in the mammalian central nervous system . Dendritic spines are typically ~1 - 2 m in length and 0.51 m in width of the spine head, with diverse morphologies, such as mushroomlike, stubby, ... |
The patients were prospectively recruited in the diabetes department of jean verdier hospital between 1992 and 2006 . Eligibility criteria included type 2 diabetes; no history of myocardial infarction or angina pectoris; normal 12-lead resting electrocardiogram (ecg); and presence of at least one of the following addit... |
Posterolateral rotary knee dislocation is a rare orthopedic injury that is considered to be irreducible by closed reduction because of soft tissue incarceration . Here, we present a case of posterolateral rotary knee dislocation, which was reduced by closed manipulation . The patientwas a 33-year - old man who sustaine... |
In early 2016, we sent a 70-question survey to the original 56 designated us hlius, including the 10 resptcs . Results were collected through adobe acrobat pro (https://acrobat.adobe.com/us/en/acrobat/acrobat-pro.html) and analyzed by using descriptive statistics . The university of nebraska medical center institutiona... |
We appreciate prof . Di guardo s interest in our recent work published in nature methods where we describe that a subpopulation of cancer stem cells (cscs) present in numerous epithelial solid tumors contains intracellular autofluorescent vesicles . We would like to take this opportunity, however, to formally address s... |
The triathlon is a relatively new sport with only three decades of competition at international level . The triathlon involves a combination of three separate disciplines - swimming, cycling and running . The order of events is usually swimming, cycling, and running although some professional sprint triathlons vary . T... |
Malaria is one of the major public health problems worldwide causing more than one million deaths each year . It is widespread in hot humid regions of africa, asia, and south and central america . According to world health organization (nearly 85% of malaria is caused by plasmodium falciparum and is responsible for abo... |
Antibodies are multifunctional glycoproteins, able to bind antigens through variable fab domains and cellular receptors via the constant fc region . This dual functionality enables the recruitment of the cellular immune system to sites of infection by antibody - dependent cellular cytotoxity (adcc) and antibody - depen... |
Within the decade, treatment of urinary incontinence and prolapse using meshes has gained popularity . The use of synthetic meshes is becoming increasingly common to optimize surgical outcome and to reduce recurrence rates . It allows the development of new connective tissue, which is deficient in genital prolapse . Po... |
Eif4e - binding protein 1 castration - resistant prostate cancer eukaryotic translation initiation factor 4e mammalian target of rapamycin complex 1 tumor suppression protein 53 positron emission tomography phosphatase and tensin homolog accelerated glucose metabolism in cancer cells under aerobic conditions, a phenome... |
Natural killer (nk) cells are derived from bone marrow - derived lymphocytes and belong to the innate immune system . In contrast to t and b cells, activation of nk cells is controlled by germ line - encoded receptors that do not undergo somatic dna recombination and mutation . Nk cells can provide early immune defense... |
The online version of this article (doi:10.1007/s40121 - 015 - 0100-z) contains supplementary material, which is available to authorized users . Linezolid (lzd) is an oxazolidinone antibiotic characterized by a wide spectrum of activity against gram - positive pathogens resistant to -lactams and glycopeptides, and its ... |
Cystic fibrosis (cf) is one of the most common genetic diseases among caucasians . The illness is best known for affecting the respiratory system, where the lungs become obstructed with thick sticky mucus, resulting in difficulty breathing and increased susceptibility to bacterial infections . The disease also affects ... |
Sunlight absorption by biological molecules plays a crucial role in life development and sustains the earths energy cycle; as a counterpart, photoprotective mechanisms are necessary to minimize the potential damage of the uv portion of the solar spectrum that reaches organisms.1 the interest in natural uv photoprotecti... |
Subependymomas are uncommonly encountered ependymal tumors, accounting for less than 1% of all intracranial neoplasms and are distinguished from ordinary ependymomas by their overall better prognosis . It has been reported that there is 0.7% incidence of subependymoma among 1,000 patients with pathologically proven int... |
Tailgut cysts or retrorectal cystic hamartomas are rare congenital presacral lesions identified in all age groups . They are believed to arise from the remnants of the embryonic hindgut . Malignancy in tailgut cysts is extremely rare, the majority being adenocarcinomas and carcinoid tumors . A unique feature of our cas... |
Determinar o impacto da implantao de um sistema informatizado de suporte deciso clnica combinado com seminrios instrucionais na utilizao de profilaxia para tromboembolia venosa (tev) de forma adequada . Estudo transversal em duas fases (antes e depois da implantao de um novo protocolo de profilaxia para tev) para avali... |
Down syndrome is the most common chromosomal disorder, occurring in every 700 to 1000 births . The average life expectancy of down syndrome patients has been prolonged, up to 50 yr according to recent reports (1). With this longer life expectancy, it is getting more and more important for down syndrome patients to have... |
As soon as the pre - mrna has been transcribed from dna in the nucleus, it is processed into a mature ribonucleoprotein (mrnp) particle, which is competent to be exported from the nucleus . The tho complex, a nuclear protein complex conserved from yeast to humans, is involved in the biogenesis of mrnp particles and fun... |
Melanins are biological pigments that are found in human skin in two forms: black / brown eumelanin and red / brown pheomelanin . Pump this technology has shown that increased eumelanin content correlates with increasing severity of a melanoma diagnosis . Recently, we found that pump probe microscopy is also sensitive ... |
Molecular imaging techniques such as positron emission tomography (pet) and single photon emission computed tomography (spect) enable the in vivo characterization and measurement of biologic processes using high - affinity and high - specificity molecular probes . Pet and spect use molecules labeled with a radionuclide... |
Cranioplasty is performed for calvarial defects due to the facts that this region is vulnerable to trauma, calvarial defects may cause cerebral atrophy and convulsions or for cosmetic purposes7,10,12). Improvement of neurological deficits, control of convulsions and partial prevention of cerebral atrophy are achieved a... |
During the past 20 years, gtp - binding proteins of the rho family have been identified as essential players in many cellular functions, and the basics of their biology have been reviewed extensively . This branch of the ras super family encompasses 22 genes in humans, of which rho, rac and cdc42 are the best character... |
The precise mechanism of ribosomal peptide bond formation was always a matter of controversial debates starting from the assumption that a ribosomal protein of the 50s subunit catalyses protein synthesis . The ph dependence of the reaction suggested an ionizable group with a pka value between 7 and 8, thus a histidine ... |
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