sha256
stringlengths
64
64
language
stringclasses
28 values
size
int32
1
491k
lines
int32
1
23.2k
content
stringlengths
1
200k
67a54c8d5f16318afee977702f7419eb0cac58cdf15824fdb141495f86f0465b
Jupyter
9,091
271
# %% [markdown] # # Table of contents # # **1. Installation & setup** # - Install bombcell package # - Import libraries and set up paths # - Configure parameters for both quality metrics and ephys properties # # **2. Quality metrics analysis** # - Run bombcell quality control pipeline # - Classify unit...
741e0778d056c3e78d5b84602f448e7bdb543d07c750d2b37a1c156079a611c8
Jupyter
9,093
192
# %% [markdown] # # 【使い方】 # # ランタイム>すべてのセルを実行(**Ctrl+F9**)によりすべてのセルを実行し、セル[2]の最後に生成された**URL(Running on public URL)をクリック**して開いてください。(GUIが新しいタブで開かれる) # # ※このcolabの画面(タブ)は閉じないでください。 # # # # # # [How to use] # # Run all cells by selecting Runtime > Run all cells (**Ctrl+F9**), and **click the URL generated at the en...
4232abca301859123a890d8e2e488f967d06a96b0172b9fc2128898fbd9fba56
Jupyter
9,099
271
# %% [markdown] # # Table of contents # # **1. Installation & setup** # - Install bombcell package # - Import libraries and set up paths # - Configure parameters for both quality metrics and ephys properties # # **2. Quality metrics analysis** # - Run bombcell quality control pipeline # - Classify unit...
cb4fea8300d4d4dbf08291ebcd4f64c988ada03a705ae1076fd5582644acad8a
Jupyter
9,099
268
# %% import pandas as pd import numpy as np from wordcloud import WordCloud import matplotlib.pyplot as plt import nltk as nltk # %% [markdown] # # RELISH data analysis # %% RESLISH_Data_PATH = "../data/Input/RELISH/TSV/sample.tsv" relish_data = pd.read_csv(RESLISH_Data_PATH, sep='\t') relish_data.head() # %% print...
064ce6131f597a61deca1a6ac2b63892536ccd7e9c9aea891579bcc35afaea21
Jupyter
9,145
227
# %% [markdown] # This notebook generates Figure 5 from the manuscript `Asgeir Kobro-Flatmoen, Jagir R. Hussan, Peter J. Hunter, Stig W. Omholt, "High reelin expression can explain why the entorhinal cortex is a cradle for Alzheimer’s disease", [doi: https://doi.org/10.1101/2025.06.04.655278]`. Readers should consult t...
6a48d879fc069681f94ae30c04fe3822ad9d17d6096c35bd2f12e75a88a995e0
Jupyter
9,229
285
# %% [markdown] # ### # ## Phase Neural Operator (PhaseNO) # ### PhaseNO for multi-station earthquake detection and phase picking # ### - Plot results - # # ##### Author: Hongyu Sun # ##### Email: hongyu-sun@outlook.com # %% import os import obspy import numpy as np from tqdm import tqdm import pandas as pd from da...
b885ecc43b45c197bdc9c7255086d8f6ce86dacd12c8f5d6c63409fd80f5f1c5
Jupyter
9,240
271
# %% [markdown] # # Table of contents # # **1. Installation & setup** # - Install bombcell package # - Import libraries and set up paths # - Configure parameters for both quality metrics and ephys properties # # **2. Quality metrics analysis** # - Run bombcell quality control pipeline # - Classify unit...
8474ea2da0db5a435a0c25834eabc75bf6c3242f3f4b8ed3451411c795c8431f
Jupyter
9,246
373
# %% [markdown] # ## Figure 5 # %% import sys import os os.environ["JAX_PLATFORMS"] = "cpu" # Get the absolute path to the project root (one directory up from notebooks/) root_path = os.path.abspath("..") sys.path.append(root_path) import pandas as pd import numpy as np import matplotlib.pyplot as plt from src im...
e2f5e9ff0a413f2fae3650f1da39a1b003d550ee9f4a32188686d15c5da53db1
Jupyter
9,281
298
# %% import os import SimpleITK as sitk import pydicom as pydicom from tqdm import tqdm import subprocess import pandas as pd import ants import antspynet import shutil import time # %% [markdown] # # Gathering non-FS T2w Image Samples # %% DATA_DIR = r"/home/thulasiseetha/research/dataset/curated/BrainMR/t2w_n...
60d06a266a3528ca7f93bb48090e1be1b9d7609cd335d60d55dd637a865fbb59
Jupyter
9,288
255
# %% %matplotlib inline import sys sys.path.append("..") import numpy as np from simulator import AnalogCore from simulator import CrossSimParameters from simulator.devices import idevice import scipy.linalg import matplotlib.pyplot as plt from PIL import Image import warnings warnings.filterwarnings("ignore", category...
c21f74bd6a478d4685594448bc79a910c61158c48f54e8cce548ae6781066639
Jupyter
9,294
257
# %% [markdown] # # Clustering with full data SMD genes # %% [markdown] # ## 1. Import packages # %% # Import all the packages import numpy as np import pandas as pd from scipy.io import mmread, mmwrite from scipy.sparse import load_npz, save_npz, coo_matrix, csr_matrix, vstack from scipy.ndimage import gaussian_fil...
8458124b6051d857ec8cdb36f0251d5c542bd5959eef8550793a41ba5e8cb18c
Jupyter
9,353
263
# %% import numpy as np import pandas as pd import matplotlib.pyplot as plt from scipy import stats from scipy.stats import gamma from scipy.signal import butter, filtfilt # %% # Set random seed for reproducibility np.random.seed(42) # Parameters n_groups = 9 n_infants = 15 n_channels = 10 sampling_rate = 10 dura...
39d11ab839236141f72cd133758a35a28901c6e450027756182bd8cae03bc2e6
Jupyter
9,395
263
# %% [markdown] # # Playground 4: Segmentation workflows for curvi-linear structures # # This notebook contains the workflows for Sec61 beta, Tom20 and Lamin b1 (mitosis-specific), and serves as a starting point for developing a classic segmentation workflow for your data with curvilinear shapes. # # ---------------...
b7af1a6663bea0527e363cedb32898a9f6ba2bc2c2e8f0eba763213e00caf9a9
Jupyter
9,554
256
# %% [markdown] # # Plat et al. — Fitting RL+kernel and Meta-RL by chi² # # Demonstration of the simulation-based fitting procedure used in the paper. Both models are fit by minimising a chi² distance between simulated and observed behavioural measures via differential evolution. # # Two fitting modes are illustrated...
e408e41d360dd125ddb978f8a0fb79fb1f03e373a92cb424c8c9b2d237562e72
Jupyter
9,602
285
# %% [markdown] # # Process trial data — habituation # # Segment the habituation `raw_data.json` into per-trial records (`trial_data.json`). # %% import pandas as pd import os import numpy as np from cichlid_omr.config import data_dir, load_config, output_dir cfg = load_config() # %% json_filename = data_dir() / cf...
b0f61c7584d5751d7bb442a6bf52a1bf2398a6adf5d3580d11b94acbfabf6971
Jupyter
9,633
399
# %% # mRNA-FM Tutorial # %% [markdown] # ### Workflow of our tutorial # # **Preparation** # 1. install the RNA-FM package # 2. load the necessary libraries # # **Task 1. RNA family clustering** # # Goal: to demonstrate that RNA-FM embeddings are biologically meaningful # # 1. read RNA sequences for each family fr...
c2d2d570d6715dd1719e35dd6daa4888f2c5ff559fb1cda7a5ee769f58844561
Jupyter
9,640
291
# %% # ========================== # Cell 1: Imports & Data Load # ========================== import os import pandas as pd import numpy as np import requests import json import logging import time from typing import List, Dict, Any, Optional from enum import Enum from dataclasses import dataclass from sklearn.metric...
1b8262911f0943a01db1336b739828ee11c51145c1e945f6adcb7435167d5fea
Jupyter
9,663
301
# %% [markdown] # Incorporate into function to run all with variables: channel list, chromophore, age, location # %% %matplotlib inline %reset import matplotlib.pyplot as plt import numpy as np import pandas as pd import pickle import skfda import sys from matplotlib import cm from scipy.integrate import simpson fr...
31b92fc79534f0947c4867fdb5b0b634c186a64f53e896a2d02fa3021677343a
Jupyter
9,691
246
# %% [markdown] # # Playground 8: Segmentation workflows for filamentous structures # # This notebook contains the workflows for Tight junction protein ZO1, Beta actin, Non-muscle myosin IIB, Alpha-actinin-1, Alpha tubulin, Troponin I, and Titin. It also serves as a starting point for developing a classic segmentatio...
243ff2e2f07ed65a1cba3912310bccffbea0ee61e4f6d9709238b1b1291f9dd5
Jupyter
9,698
289
# %% [markdown] # # Individual fish trajectories # # Per-fish trajectory and behaviour example plots. # %% import pandas as pd import matplotlib.pyplot as plt import numpy as np from scipy import stats import os from cichlid_omr.config import data_dir, load_config, output_dir # %% one_cm_converted = 1/15 velocity_co...
3fb1a9300e28a545d77f5d4040df6741a5c46575c9005f511961a716a36b643c
Jupyter
9,753
273
# %% import matplotlib.pyplot as plt import numpy as np import pandas as pd import os import warnings import cmcrameri.cm as cmc from scipy.ndimage import uniform_filter import alphashape from scipy.interpolate import splprep, splev import warnings warnings.filterwarnings('ignore') #Set directories working_dir = os.ge...
4df357eb530142fb8dbfc4a9458418d0774418c2cbf125c87aabc05cec89eba7
Jupyter
9,831
317
# %% [markdown] # # Preparation # %% [markdown] # ## Load datasets # %% [markdown] # ## Import packages # %% from bin.src.utils import read_gtf, collapse_isoforms_to_proteoforms import polars as pl from scipy import sparse import numpy as np # %% from SingleCell.single_cell import SingleCell from SingleCell.utils i...
163dd1b08ebfe484109925021a8189611fbe23b94b7e7f1c25594c482d97556d
Jupyter
9,845
294
# %% import json import os import sys from pathlib import Path from os.path import join import matplotlib as mpl import matplotlib.pyplot as plt import numpy as np import pandas as pd import seaborn as sns import statsmodels.api as sm from scipy.io import loadmat, savemat from scipy.stats import ttest_1samp, ttest_rel...
9244a962252cd85dcb8b19992abb40ee5a79141c9ececc4436c52bc97bc3e8fc
Jupyter
9,945
309
# %% [markdown] # ## Figure 2 # # code for generating each plot in Fig. 2 # # Imports and needed data: # %% import sys import os # Get the absolute path to the project root (one directory up from notebooks/) root_path = os.path.abspath("..") sys.path.append(root_path) import pickle import pandas as pd import numpy...
1f36959d521854583d17f0878b744c2420af41cb32545bb4268916a28c7be817
Jupyter
10,000
220
# %% [markdown] # # Causal Games # # This notebook walks through a few examples for building intuition about backdoor paths used in *The Book of Why* by Judea Pearl. # # For each example, we take an example causal graph represented as a *Directed Acyclic Graph* (DAG), and our goal is to identify the set of deconfoun...
c239439643d91806509fe1da4339d4f78c19dea0e966b92ce0e7c878279c935c
Jupyter
10,023
257
# %% [markdown] # # Playground: Segmentation workflow for RNA # # This notebook contains the workflow to detect single-molecule RNA FISH signals that works well for us. It is based off the Allen Cell Segmenter workflow for sialyltransferase 1. # # Key steps of the workflows: # # * Auto-Contrast intensity normaliza...
8d628b181504bf1ed6d9f94d478274c98431d05939fcd714015232f90ee2670d
Jupyter
10,043
185
# %% [markdown] # # League of Legends Win Prediction with XGBoost # # This notebook uses the Kaggle dataset [League of Legends Ranked Matches](https://www.kaggle.com/paololol/league-of-legends-ranked-matches) which contains 180,000 ranked games of League of Legends starting from 2014. Using this data we build an XGBoo...
21720838bba89efae534f4590a946443996acacf965d491ba7c27d74ae773546
Jupyter
10,044
248
# %% import os os.environ["CUDA_VISIBLE_DEVICES"] = "3" os.environ["BATCH_SIZE"] = "16" import sys import json import pickle import gzip import h5py from glob import glob from tqdm import tqdm import numpy as np import pandas as pd from importlib import reload from collections import defaultdict, OrderedDict import mat...
d3e88657e13c14fb36d22a83b537f17d8cda4ff6c5fc7667a2771ea6035b638a
Jupyter
10,051
280
# %% [markdown] # This notebook generates Figures S9-S10 from the supplementary for the manuscript `Asgeir Kobro-Flatmoen, Jagir R. Hussan, Peter J. Hunter, Stig W. Omholt, "High reelin expression can explain why the entorhinal cortex is a cradle for Alzheimer’s disease", [doi: https://doi.org/10.1101/2025.06.04.65527...
daf0cb104f5d3023cc1e8e3a68419c1483fb46be451edf02720bf5f5515eabd5
Jupyter
10,053
227
# %% import anndata as ad import pandas as pd import numpy as np from scipy.io import mmread, mmwrite from scipy.sparse import csr_matrix import muon import scarches as sca from multigrate.data import organize_multiome_anndatas import scanpy as sc import scib_metrics from typing import Optional import os, sys from scip...
acc2c9d84edbdd1711fc43d1566682d697cdc32f32e427381cdfa7c75c690efd
Jupyter
10,054
303
# %% [markdown] # # Permutation-preserving Jaccard Distance (P-Jaccard) # %% [markdown] # # ### ------------------------------------------------------------------------ # ### Purpose: Generate p-values for Del-Dup burden correlations # ### Author : Sayeh Kazem # ### Last Updated: 2025-08-05 # ### Python Version: 3.1...
23292683982f5e4342f95bdd438f0cd26fcb9b3c2ebe31478394e700cf41c979
Jupyter
10,095
287
# %% [markdown] # # Clustering RH data with Scramble SMD genes # %% [markdown] # ## 1. Import packages # %% # Import all the packages import numpy as np import pandas as pd from scipy.io import mmread, mmwrite from scipy.sparse import load_npz, save_npz, coo_matrix, csr_matrix, vstack from scipy.ndimage import gauss...
7d3a4e0a77da50dc616508fc6d3f5d79d873acc386098f181b6e0203e2e94ae8
Jupyter
10,242
358
# %% [markdown] # # MobileNetV2 Evaluation on Secondary Dataset # # **Purpose:** Evaluate trained MobileNetV2 on secondary datasets for generalizability analysis # # **Model:** MobileNetV2 (trained on EyePACS) # # **Framework:** TensorFlow 2.x # # --- # # ## Configuration # # This notebook can evaluate on any of ...
3250fa7325cef38c14927ca4ea5165c788ebfe7d645235cabdc4cba139ddfd6a
Jupyter
10,246
339
# %% [markdown] # Incorporate into function to run all with variables: channel list, chromophore, age, location # %% %reset import matplotlib.pyplot as plt import numpy as np import pandas as pd import pickle import skfda import sys from matplotlib import cm from scipy.integrate import simpson from skfda.preprocessi...
f3b15e079cf6a247ae1a6c0374b2eab373ebab224726ad795cb2c00a8286a018
Jupyter
10,283
365
# %% [markdown] # ## Tumor microenvironment (TME) spatial niche analysis # %% [markdown] # Here we will use 10X Xenium breast cancer dataset as an example to illustrate how Garfield performs spatial niche analysis and niche characterization. Data access: https://www.10xgenomics.com/products/xenium-in-situ/preview-data...
c7aa52c2b534c290224d1b10e3d2d8c1e0ef35a303f0841c0ea28fde3e145da0
Jupyter
10,290
215
# %% [markdown] # This notebook is a guide to reproduce all the models run on the C4 datasets. # # Most of the code needed is already included into [npyx](www.github.com/m-beau/NeuroPyxels), so the following Notebook will be just a guide on the order to run things to fully reproduce what was done. # %% [markdown] # #...
67e704afab69d3d1aaad9c2eec36b62ccdb00d621d531a8fa1704d27a0ed68f2
Jupyter
10,372
238
# %% [markdown] # This notebook is for comparing sbi's joint posterior distribution to dadi Godambe uncertainty interval. # We use the 2-epoch model of Arabidopsis in stdpopsim with fixed ancestral population size to 1e4. # Training data is prepared by simulating 10Mb leftmost segment of Chr1. # Dadi uses normalized ...
5214075fe826d94c7ef3094e743cb444e4a6fd2ae5094ab769e2fda079d4fdbc
Jupyter
10,385
440
# %% import numpy as np import matplotlib.pyplot as plt from matplotlib.lines import Line2D from matplotlib.collections import LineCollection import os import sys sys.path.append("../") from models import ( simulate_model, ) from utils.model_utils import ( simulate_honeycomb_trajectory, compute_spatial...
ea57706aa40cca0df5cd8a4c43a617c2e40e1863db70ca065da981658e801d24
Jupyter
10,415
381
# %% [markdown] # # CvT Evaluation on Secondary Dataset # # **Purpose:** Evaluate trained CvT on secondary datasets for generalizability analysis # # **Model:** CvT-21-384 (trained on EyePACS) # # **Framework:** PyTorch + HuggingFace Transformers # # --- # # ## Configuration # # This notebook can evaluate on any ...
9f6430fd4b95383579f35de6eabde17e2075f464941a541cecbd59066c867a53
Jupyter
10,433
270
# %% [markdown] # # Playground 5: Segmentation workflow for LAMP-1 # # This notebook contains the workflow for LAMP-1, and serves as a starting point for developing a classic segmentation workflow if your data shows similar morphology as LAMP-1. # # ---------------------------------------- # # Cell Structure Observ...
3749cbd6169f9a4bd500d630056ec9148381a6101192b03d0cef1aa0ccdc5d54
Jupyter
10,460
323
# %% %matplotlib inline %reset import matplotlib.pyplot as plt import numpy as np import pandas as pd import pickle import skfda import sys from scipy.integrate import simpson from skfda.preprocessing.dim_reduction import FPCA from skfda.representation.basis import BSplineBasis from statsmodels.stats.multitest impor...
599a3ae2bf3e603770ee3c09929e5df2f2c6c6718daa2cc4ea08870f7168e692
Jupyter
10,479
335
# %% [markdown] # ## Installation and Imports # %% import os import re import gzip import jax.numpy as jnp import numpy as np import matplotlib.pyplot as plt from mpl_toolkits.axes_grid1 import make_axes_locatable import seaborn as sns import requests from pyfaidx import Fasta # %% [markdown] # --- # # Post-Trained ...
b4ef1dd0f759c907ef64adfa519de469579e77b06ea4a44ebfb781915ab935bf
Jupyter
10,625
309
# %% [markdown] # # MNIST # %% %load_ext autoreload %autoreload 2 # Import dependencies import os import importlib import numpy as np import matplotlib.pyplot as plt import time import torchvision import seaborn as sns import numpy as np import pytorch_lightning as pl import torch.nn.functional as F import torchvision...
9f3e6e17489487cf759d4b80da9785e00c06a616be5a6a145ac3e4b56c959209
Jupyter
10,628
308
# %% import numpy as np import scanpy as sc import pandas as pd # import cosg import pandas as pd import numpy as np import time import os def ssim(part1, part2): # Replace NaN values with 0 mu1 = np.mean(part1) mu2 = np.mean(part2) C1 = 0.01**2 C2 = 0.03**2 numerator = (2 * mu1 * mu2...
00390cd30931030269b9eff7d67ed12012d23054f750f454b872a6ede75e42db
Jupyter
10,652
274
# %% [markdown] # # NHANES I Survival Model # # This is a cox proportional hazards model on data from <a href="https://wwwn.cdc.gov/nchs/nhanes/nhanes1">NHANES I</a> with followup mortality data from the <a href="https://wwwn.cdc.gov/nchs/nhanes/nhefs">NHANES I Epidemiologic Followup Study</a>. It is designed to illus...
a49b4d32094fc44e36211f115299d79d7b66dd791d7f59c9586de152573919d9
Jupyter
10,699
312
# %% [markdown] # # GRN Inference on Pre-trained Model # Here we use the pre-trained blood model as an example for GRN inference, particularly regarding gene program extraction and network visualization. We also present the cell-type specific activations within these gene programs on the Immune Human dataset, as a soft...
efe938f02530bf9fd40a381c72b2bdb422e2f333b12f5de32450cec220f78be5
Jupyter
10,810
251
# %% library(dplyr) library(Matrix) library(data.table) library(Seurat) library(ggplot2) library(RColorBrewer) library(cowplot) library(future) library(viridis) library(SeuratObject) library(tidyr) plan("multicore", workers = 16) options(future.globals.maxSize = 100 * 1024^3) library(ComplexHeatmap) library(pheatmap) l...
232545117329ff505323399fd626575818a8e3551d7857add9cfa911a4e66eff
Jupyter
10,832
269
# %% from mpl_toolkits.axes_grid1 import make_axes_locatable from sklearn.neighbors import KernelDensity import matplotlib.pyplot as plt import numpy as np import scipy.io import json import os import sys path_root = '../../../BONNA_decide_net' sys.path.append(os.path.join(path_root, 'code')) from dn_utils.behavioral_...
b4d89a2d6efdfe2eb16d3e5d05601eeff7753822a6adb2315ab056775d5a55a9
Jupyter
10,890
319
# %% [markdown] # # Performing SMD on RH data # %% [markdown] # ## 1. Import packages # %% # Import all the packages import numpy as np import pandas as pd from scipy.io import mmread, mmwrite from scipy.sparse import load_npz, save_npz, coo_matrix, csr_matrix, vstack from scipy.ndimage import gaussian_filter1d from...
878bb5ca082686c1c7cab993ecd46607b11e50623346b5f16984c6d031719230
Jupyter
10,896
357
# %% [markdown] # ## Inputs # --- # %% # reading data and working with arrays import os import zarr, nrrd import numpy as np import os # data paths p = '/Users/goinac/Work/HHMI/bioimagetools/nextflow-modules/mylocal/bigstream-testdata3' fix_path = p + '/fix.n5' ref_ch = 'c0' fix_s0_subpath = f'{ref_ch}/s0' mov_path =...
f2b20fff23779c3a31c5d41714ffcd4ef6055f3a4b438d2329098ebaab9f5696
Jupyter
10,902
332
# %% [markdown] # ## Reporting GLM results # # This script creates activation plots and clusters table used to report GLM findings. Responsibilities: # - loads second level statistical parametric maps (spm's) # - threshold spm's and extract information about active clusters # - generates tables with information about ...
6b41eed1af4199c8749766b387a269bed03a58e5b0f46975aa5d5ef03d646520
Jupyter
10,931
316
# %% [markdown] # ## Getting started with bombcell # %% [markdown] # # Quick Navigation # # **Jump to sections:** # - **[Installation & Setup](#installation--setup)** - Install BombCell and configure parameters # - **[Section 1: Quality Metrics](#section-1-quality-metrics)** - Run BombCell quality control and unit cl...
f1f2badc08537719879fe7ed58723856450d6d6f93074e5bae51b2cb35897fb0
Jupyter
11,004
383
# %% [markdown] # # MobileNetV2 Training on EyePACS Dataset # # **Purpose:** Train MobileNetV2 architecture for binary DR classification (referable vs. non-referable) # # **Dataset:** EyePACS (primary dataset) # # **Framework:** TensorFlow 2.x # # **Reference:** Sandler et al. (2018) - MobileNetV2: Inverted Residua...
00ba8a6c25c5ef80ff308b7873f0b540a5b15c8814b3d160a8723b5f95f370bf
Jupyter
11,009
269
# %% [markdown] # # Playground 3: Segmentation workflow for Nucleophosmin # # This notebook contains the workflow for Nucleophosmin, and serves as a starting point for developing a classic segmentation workflow if your data shows similar morphology as Nucleophosmin. # # ---------------------------------------- # # ...
724d60b258e0f5229113d9bbf9cc96d026da13753df961cd5f5dd53a38846413
Jupyter
11,015
366
# %% [markdown] # ### seqFISH Mouse Organogenesis datasets # %% import os import pandas as pd import numpy as np os.chdir('/pri_exthome/zhouwg/project/Garfield') os.getcwd() # %% # load packages import os import warnings import Garfield as gf import scanpy as sc import numpy as np import pandas as pd from mudata imp...
57ad1a2897bd5a32b6b0486ef68a971f3e328bafd12c0d7229abc1c43638f1ae
Jupyter
11,043
370
# %% [markdown] # # Plot the results of the SymmNet experiments (fig. 8) # # In this experiment, we apply SAL to the training of a deep convolutional neural network and compare its performance to competing symmetrization algorithms. # Learning happens in two phases: In each epoch, the forward weights $W$ are trained ...
93fa4ad6238a2e0806cb3a79c505d0efaecb040416e6c959e6a3f25902adcecc
Jupyter
11,116
300
# %% import numpy as np import random import math from scipy.stats import norm from scipy.integrate import quad from scipy.optimize import minimize, basinhopping import matplotlib.pyplot as plt # %% def sample_z(n, annot, p, s2, s02, r2_het_ss): z_sample = [random.gauss(0, math.sqrt(s02)) for _ in range(n)] fo...
f713ac08c6b7dad16a391e26736b75753732c3a7a5be85e99dae69f390936b20
Jupyter
11,164
295
# %% import json import os import numpy as np import pandas as pd import matplotlib.pyplot as plt import matplotlib.font_manager as font_manager import urllib.request from statsmodels.nonparametric.smoothers_lowess import lowess if not os.path.exists('IBMPlexMono-Regular.ttf'): urllib.request.urlretrieve( ...
f8f1a1796d10f4db1e69c6652b77a1cdcf9a9216cd3c2399a6fe5d7511c422a8
Jupyter
11,182
354
# %% [markdown] # # Fig 6c: model fLoc selectivity by stream # Analyze contrast t-values for units assigned to different streams. # %% import os import sys from pathlib import Path import numpy as np import pandas as pd import matplotlib as mpl import matplotlib.pyplot as plt import seaborn as sns import h5py from it...
327d5065ee7d86e178e0ad45f983d1a270f03a7f3bee1979bfc86757fb041059
Jupyter
11,185
381
# %% import radiomics import ants import torchio as tio import os from tqdm import tqdm import pandas as pd import SimpleITK as sitk import pydicom as pydicom import numpy as np from scipy.spatial import distance import gui import registration_gui as rgui import matplotlib.pyplot as plt import concurrent.futures ...
7c971b3de479b100a576380466ab345edf141cf77736b4d77198b79143592edd
Jupyter
11,194
375
# %% ############ Conducting a sensitivity analysis on results with different bin sizes. # %% library(Seurat) library(ggplot2) library(dplyr) library(Matrix) library(data.table) library(Seurat) library(ggplot2) library(RColorBrewer) library(cowplot) library(future) library(ComplexHeatmap) library(viridis) library(Seur...
806bbeb1c5aa7465cf493bdadb35754d4a57664389e39e493b9db932ee51cc80
Jupyter
11,217
299
# %% import pandas as pd import numpy as np import os import matplotlib.pyplot as plt import seaborn as sns from tqdm import tqdm import re # %% def analysis_data(data): # data = data[['utr', 'utr_originial_varylength', 'label', 'y_pred', 'y_true']] # data['y_true'] = data['label'] # data['y_pred'] = data[...
1a8c7f8dadb81e043e61d08b8fbe1180dc075664f8165ba2a340b0d7450d720b
Jupyter
11,286
289
# %% [markdown] # # Load ICA results # %% import numpy as np data_dir = 'PCA_then_ICA' # 1024 patches per video, 20000 iterations stationary_responses_nonrandom = np.load(data_dir + "/stationary_responses_nonrandom_multi_dist_FastICA.npy") moving_responses_nonrandom = np.load(data_dir + "/moving_responses_nonrandom_...
773bdcf7e67ae930314bcec3676fc685132e5902d9239ea7aaaff129deca0728
Jupyter
11,297
419
# %% [markdown] # # CvT Training on EyePACS Dataset # # **Purpose:** Train CvT (Convolutional vision Transformer) for binary DR classification # # **Dataset:** EyePACS (primary dataset) # # **Framework:** PyTorch + HuggingFace Transformers # # **Reference:** Wu et al. (2021) - CvT: Introducing Convolutions to Visio...
7151aeab82a54e24f9b7484fc3839126b257c1b64274bcbee2ec4a41049bd888
Jupyter
11,423
303
# %% %pylab inline import pandas as pd import scanpy as sc # %% def postprocess(adata,view=True): sc.pp.normalize_total(adata, target_sum=1e4) sc.pp.log1p(adata) sc.pp.highly_variable_genes(adata) adata.raw = adata adata = adata[:, adata.var.highly_variable] print('after select HVG',adata.shape...
d126b11eeb6d764789fc44b10c3837fb64e4abd91fd606f5867074b5abf43906
Jupyter
11,430
392
# %% suppressMessages({ library(Seurat) library(ggplot2) library(dplyr) library(pheatmap) library(cowplot) library(RColorBrewer) library(dplyr) library(ComplexHeatmap) library(RColorBrewer) cols = c(brewer.pal(9, "Set1"),brewer.pal(8,"Set2")[1:8],brewer.pal(12,"Paired")[1:12],brewer.pal(8,"Dark2")[1...
f0622bb6fb981bda07128c18515f5c9294b967b31703bfa85b2ec175853883e8
Jupyter
11,467
340
# %% [markdown] # ### Training on real data # # Here we train on real publicly available data. # # For this example a GPU is required to train the model in reasonable time. # %% import sys import os sys.path.append("engine/") sys.path.append("funcs/") sys.setrecursionlimit(10000) import theano.gpuarray theano.gpuar...
3e4770052f9bfd0921d964af80d3b8486f8155170fe472aed5f95bc8d7c921b5
Jupyter
11,481
407
# %% [markdown] # # Plot the results of the spiking microcircuits experiments (fig 6) # # In this experiment, we show how SAL presents a solution to a missing piece in cortical models for biologically plausible error transport. # We investigate this subject in the model cortical microcircuits ([Sacramento et al. 2028]...
16d6eb5b9b0d4a1ecd2b2390fa75ba18a2e40b61ab468d973a0baa09b44a0eeb
Jupyter
11,484
263
# %% import os os.environ["CUDA_VISIBLE_DEVICES"] = '2' # set GPU id to use import sys import numpy as np import pandas as pd from importlib import reload from collections import defaultdict, OrderedDict import matplotlib.pyplot as plt new_rc_params = {'text.usetex': False, 'svg.fonttype': 'none' } plt.rcParams.update(...
54b38eea83bc20953741eb6eafc89c2ffe67e89b233ac8c510d61b94dde57ae7
Jupyter
11,517
391
# %% [markdown] # # Simulate a 2 neuron E-I system (fig. 10) # # ... to demonstrate the concept of an effective weight in the context of multiple Pathways and the compatibility of SAL with Dale's law. # # --------------- # # In this script, we will address a question that we have deliberately sidestepped until now, ...
9e156799eccc8d301e71d4ccb91590292f16e3c96d2ac19268d23bf89deff133
Jupyter
11,543
320
# %% %load_ext blackcellmagic %load_ext autoreload %autoreload 2 # %% [markdown] # #### Imports and setup # %% import numpy as np import pandas as pd import h5py import nibabel.freesurfer.mghformat as mgh import statsmodels.formula.api as sm from statsmodels.stats.multitest import multipletests from scipy.stats impo...
1ee78c91c62fbef61d45cb3630f0641c2fcb647efd0e3eff6d1eac1566d15608
Jupyter
11,620
261
# %% [markdown] # # Playground 6: Segmentation workflows for "dots"-like structures # # This notebook contains the workflows for Centrin-2, Desmoplakin, and PMP34, and serves as a starting point for developing a classic segmentation workflow for your data with dots-like shapes. # # ----------------------------------...
b4803088902ff4c15a50ad1c920fdcc088a8b5d07014bb51f04158c82387caf7
Jupyter
11,672
365
# %% [markdown] # ## Super-Resolution Application with CPS # - infer gene expression with higher resolution of spatial position # %% import os,sys sys.path.append(os.path.realpath(os.path.join(os.getcwd(), '..'))) import warnings warnings.filterwarnings("ignore") # %% import scanpy as sc import pandas as pd import nu...
8ac02b17424ab7c0a0c12b5b6a6339c17f5ef4804573b3388d539564679abca7
Jupyter
11,700
367
# %% import torch import torch.nn as nn import matplotlib.pyplot as plt print("PyTorch:", torch.__version__) print("CUDA :", torch.cuda.is_available()) if torch.cuda.is_available(): print("GPU name:", torch.cuda.get_device_name(0)) import pandas as pd from matplotlib.transforms import Bbox as BB from google....
409288938a6e90cbc5623281a4f19e879cb8d049ab4a8cbba41fe7f4df9bc8ce
Jupyter
11,748
264
# %% [markdown] # # 3_SynAnalyzer_CompileXYZData.ipynb # # This Python notebook reads in the CSV files generated in 2_SynAnalyzer_AnalyzeXYZs.ijm that were annotated by the user during # manual array scoring. These files were saved in SAR.Analysis. This code pulls these files and the associated Metadata files # from t...
35f225e40fd9f51b508b2eab783e934ea3df7a56d3eb5d212bf67a27b8ba380b
Jupyter
11,789
349
# %% [markdown] # # Zero-shot reference mapping tutorial with scGPT # %% [markdown] # ## Introduction # # This tutorial covers the zero-shot reference mapping with scGPT. This workflow achieves accurate and fast reference mapping for scRNA-seq datasets without fine-tuning (or any extensive training) of scGPT. To furt...
333af307b8924053298630ac6ae74f81277f4602aa76ce44c2bbeb3721ae518c
Jupyter
11,799
387
# %% [markdown] # ## Spatial tissue niche discovery (single-modality spatial data) # %% [markdown] # Here we will use slideseqv2_mouse_hippocampus datasets as an example to illustrate how Garfield performs spatial tissue niche discovery for multiple batches. Data access: https://singlecell.broadinstitute.org/single_ce...
0f4281d77b52aec7f23af75153e1d1c57172933eb868160dbaa3e08b498f1075
Jupyter
11,821
249
# %% [markdown] # # Domains labeling # # When running `model.assign_domains`, the output domains are identified only by opaque IDs such as `D1003`, `L4`, and similar IDs. While sufficient for computation, these identifiers are difficult to interpret biologically. # # In practice, it is often preferable to replace the...
83414cdb2543860ee9a41e6927c4dde8c1c7333bc55f27f808bc6cf56f5bdb0f
Jupyter
11,831
329
# %% [markdown] # This notebook generates Figures S11-S13 from the supplementary for the manuscript `Asgeir Kobro-Flatmoen, Jagir R. Hussan, Peter J. Hunter, Stig W. Omholt, "High reelin expression can explain why the entorhinal cortex is a cradle for Alzheimer’s disease", [doi: https://doi.org/10.1101/2025.06.04.6552...
e4b79f53123c850f4340bf549ba4ba47b7ad4e33af6c472e0a85fe1426a004fa
Jupyter
11,860
293
# %% [markdown] # This notebook generates Figure S7 from the supplementary for the manuscript `Asgeir Kobro-Flatmoen, Jagir R. Hussan, Peter J. Hunter, Stig W. Omholt, "High reelin expression can explain why the entorhinal cortex is a cradle for Alzheimer’s disease", [doi: https://doi.org/10.1101/2025.06.04.655278]`. ...
b12c57b386b4d795750260ebaf24fd8c62e339e37a6f39c38d5b4f1e423e1a8e
Jupyter
11,916
366
# %% [markdown] # # Inference with Segment-NT models # %% [markdown] # [![Open All Collab](https://colab.research.google.com/assets/colab-badge.svg)](https://colab.research.google.com/github/instadeepai/nucleotide-transformer/blob/main/notebooks/segment_nt/inference_segment_nt.ipynb) # %% [markdown] # ## Installation...
30181e7e8163f9190d11f6467874f729111b7a7a4899ea38ed7fc2874f78c5a5
Jupyter
11,952
250
# %% [markdown] # # PyTorch Deep Explainer DeepSEA example # # Running the pytorch Deep Explainer on the DeepSEA model from the kipoi repo # %% [markdown] # First, we pull the kipoi pytorch model and load it up # %% import torch #pull the model from kipoi ! [[ -f deepsea_model_architecture.py ]] || wget https://raw...
22722d8444b825de82f3b4abaadd9e18a2e7151bec32c24742d23a84ecf1cd4b
Jupyter
11,966
298
# %% [markdown] # This notebook generates Figure S8 from the supplementary for the manuscript `Asgeir Kobro-Flatmoen, Jagir R. Hussan, Peter J. Hunter, Stig W. Omholt, "High reelin expression can explain why the entorhinal cortex is a cradle for Alzheimer’s disease", [doi: https://doi.org/10.1101/2025.06.04.655278]`. ...
c536d69122c46d4d17da019f8edde5f58e08e41d42eac6614e6a84a8a95350ec
Jupyter
12,080
312
# %% import os os.environ['PYTORCH_CUDA_ALLOC_CONF'] = 'expandable_segments:True' from typing import Dict import warnings warnings.filterwarnings('ignore') import copy from tqdm import tqdm import random import scanpy as sc import numpy as np import pandas as pd import torch from torch.utils.data import Dataset, DataLo...
d7b1108e88487680497a9b100ee527501cfcbf8c3c29e3061d72df27bcd2a4e9
Jupyter
12,187
297
# %% [markdown] # # Playground 1: Segmentation workflow for sialyltransferase 1 # # This notebook contains the workflow for sialyltransferase 1, and serves as a starting point for developing a classic segmentation workflow if your data shows similar morphology as sialyltransferase 1. # # ----------------------------...
f12270cd9037eb65af9374c60d31a4578c9e90ed6b82aa902660693aad38739d
Jupyter
12,216
306
# %% [markdown] # # Spectral Event Analysis Tutorial # %% [markdown] # This tutorial is a hands-on introduction to using the [SpectralEvents toolbox](https://github.com/jonescompneurolab/SpectralEvents), **a collection of functions designed to help researchers characterize high-amplitude peaks in the time-frequency re...
702a8acaa6390f0f5bff286fdc342ad85b28c67a67d72711a27eb38639a07853
Jupyter
12,283
415
# %% [markdown] # # Zero-shot integration tutorial with scGPT # %% [markdown] # ## Introduction # # This tutorial covers the zero-shot integration with scGPT. This particular workflow works for scRNA-seq datasets without fine-tuning (or any extensive training) of scGPT. # %% [markdown] # We will use the Lung-Kim dat...
1619bae706053b48560c935a8795989f6984cefd544c6a86c88fc0caec8edce4
Jupyter
12,345
383
# %% import numpy as np import pandas as pd from scipy.stats import wilcoxon import json # %% [markdown] # ### Significance Test 1: Selectiveness # # **"For each censoring method (feature noise, label noise, omission), does sensitive performance degrade significantly more than non-sensitive performance at each noise ...
71b4b63bf7ecfdead1c1b92775e76cf6175384b112ddc29322557ed08b8ad9c8
Jupyter
12,370
268
# %% [markdown] # # HIPPIE tutorial: embedding and cross-species classification # # HIPPIE is a conditional VAE that learns technology-adjusted representations of # extracellular recordings from three modalities: the mean **waveform (WF)**, the # **inter-spike-interval (ISI)** distribution, and the **autocorrelogram (...
645d297ee12949719dfd997e7e44ba9004cfbced9b9b7723d1891e2253cfa52f
Jupyter
12,440
377
# %% [markdown] # ## Figure 3 # # code for generating each plot in Fig. 2 # # Imports and needed data: # %% import sys import os # Get the absolute path to the project root (one directory up from notebooks/) root_path = os.path.abspath("..") sys.path.append(root_path) import pandas as pd import matplotlib.pyplot a...
5c5ac8bf65b2a416924573d91e75c93e615561cf265a2559f2610233cca914f3
Jupyter
12,468
292
# %% import pandas as pd import numpy as np import os import matplotlib.pyplot as plt import seaborn as sns from tqdm import tqdm import matplotlib.ticker as mticker import numpy as np import matplotlib.pyplot as plt from sklearn.kernel_ridge import KernelRidge from scipy.interpolate import make_interp_spline from scip...
e10994c31164166e6e00cad52a076243e43ac76e6a5a48f58c9dd2dccee4999b
Jupyter
12,468
350
# %% import os import numpy as np import matplotlib.pyplot as plt from mpl_toolkits.axes_grid1 import make_axes_locatable import pandas as pd from scipy.spatial import cKDTree import warnings import numpy as np import pandas as pd import warnings from tqdm import tqdm warnings.filterwarnings('ignore') # %% [markdown] ...
3e688c3712fe014c55befec783542f9ead815acc91020eb6343ef786c1cf1ea6
Jupyter
12,484
292
# %% [markdown] # ## First level GLM analysis # # This script performs subject level modeling of BOLD response. Script features: # - reads BIDS dataset, loads imaging files, confounds and parametric modulations # - for each subject and session: # - creates parametrically modulated regressors # - creates full ...
e1dd424b8885243f1c163a50cbe1378b170dfbe98ddabd1642bd22f342b21ab2
Jupyter
12,634
462
# %% from pathlib import Path import numpy as np import pandas as pd import matplotlib.pyplot as plt # ========================= # CONFIG # ========================= SPLIT = "valid" REPORTS_ROOT = Path("../ismb26/results/segment_func_reports_bh_term") OUT_DIR = REPORTS_ROOT / "_figures" / f"knn_shared_go_qval_log2odds...
07686f6798b3685e870cc3ce57dbea173f6a7ca95d482749253b247abe37272c
Jupyter
12,724
407
# %% [markdown] # # Simple CA1 Model - Current Injection Experiment # # This notebook demonstrates a simple electrophysiology experiment: # - Build a simple soma-dendrite model with morphology: soma → dend1 → (dend2, dend3) # - Inject current into a dendrite # - Record membrane potential from soma and dendrites # - Vi...
e39dcacc73367a7c8225c2f524a4d99bb5d6dce76c479d8bd517917b3cff4d49
Jupyter
12,745
294
# %% import pandas as pd import os import numpy as np import shap import matplotlib.pyplot as plt import seaborn as sns sns.set_context("paper") dpi = 600 # %% sns.set_theme(style="white", font_scale=0.8) # %% [markdown] # ## expression or knowledge by gene # %% cell_type = ['B cell', 'CD4 T cell', 'CD8 T cell', 'Mo...
f47523983f8ed4721037da9563de33f144a042f52cd8651c1143922425744166
Jupyter
12,786
340
# %% [markdown] # # ERICA Trio # %% import numpy as np import tensorflow as tf from tensorflow.python.keras.layers import Activation from tensorflow.python.keras.layers import Concatenate from tensorflow.python.keras.layers import Conv2D from tensorflow.python.keras.layers import Dense from tensorflow.python.keras.lay...
f6c51e5238ee506ffa7ad7c1999217844981be72c80ef360287823973211055d
Jupyter
12,786
256
# %% [markdown] # # Bigstream Tutorial # --- # # Bigstream is an extremely powerful and customizable tool. This tutorial will only show a small piece of what bigstream can do, but it's a reasonable place to start. This notebook will show small image in-memory registration and large image bigger-than-memory registratio...
0f9d3fccb81150c4b94aa6474bebfa7f5536876cf35c262bb1996b3f469c2d9b
Jupyter
12,794
253
# %% [markdown] # <a href="https://colab.research.google.com/github/dauparas/ProteinMPNN/blob/main/colab_notebooks/quickdemo.ipynb" target="_parent"><img src="https://colab.research.google.com/assets/colab-badge.svg" alt="Open In Colab"/></a> # %% [markdown] # #ProteinMPNN # This notebook is intended as a quick demo, ...
e3316f9c40ffcf3e8f93de3576fa0d59cc548ec4d2d538ff80bd0aabba70ab39
Jupyter
12,806
408
# %% %load_ext blackcellmagic # %% [markdown] # #### Imports and setup # %% import numpy as np import pandas as pd import deepdish as dd import h5py import nibabel.freesurfer.mghformat as mgh import matplotlib.pyplot as plt import seaborn as sns from statsmodels.stats.anova import AnovaRM from scipy.stats import tte...