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W2059214782
A guide to writing articles in energy science
Abstract Energy science addresses key questions of sustainable development. This suggests that energy scientists should communicate their research effectively with readers both from within and outside of the scientific community. In the communication of energy science, however, scientific writing potentially presents a...
[ "Products and Processes Engineering", "The Social World and Its Interactions" ]
10.1111/1365-2435.13101
The Impact Of Development On Patterns Of Nutrient Limitation
Development is often accompanied by major changes in an organism's functioning and in the way it interacts with its environment. We consider how developmental events such as allocation changes at maturity, ontogenetic diet shift or metamorphosis may affect the likelihood and nature of nutrient limitation and explore th...
[ "Environmental Biology, Ecology and Evolution", "Physiology in Health, Disease and Ageing" ]
10.1142/s0219061320500051
Exponential-constructible functions in P-minimal structures
Exponential-constructible functions are an extension of the class of constructible functions. This extension was formulated by Cluckers and Loeser in the context of semi-algebraic and sub-analytic structures, when they studied stability under integration. In this paper, we will present a natural refinement of their def...
[ "Mathematics" ]
694578
Bacterial isoprene metabolism: a missing link in a key global biogeochemical cycle
Isoprene is a very important climate-active biogenic volatile organic compound with both global warming and cooling effects. Globally, terrestrial plants emit huge amounts (~500-750 million tonnes) of isoprene per year. This is approximately the same quantity as methane released to the amosphere. Isoprene emissions are...
[ "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Earth System Science" ]
648681
Innocent children or security threats? european children born of war
How can we ensure that children born of war do not pay for the sins of their parents? Political debates about how to address the plight of children born of foreign fighters to ISIS/Daesh make this an acute concern in Europe today. The European debates are polarized; some argue that socialization of these children will ...
[ "The Social World and Its Interactions", "Institutions, Governance and Legal Systems", "The Study of the Human Past" ]
10.1016/j.celrep.2013.07.035
RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation
For years, the term "apoptosis" was used synonymously with programmed cell death. However, it was recently discovered that receptor interacting protein 3 (RIP3)-dependent "necroptosis" represents an alternative programmed cell death pathway activated in many inflamed tissues. Here, we show in a genetic model of chronic...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing" ]
835184
Deciphering the molecular mechanisms of HIV DNA nuclear import and the impact of 3D genome organization on integration site selection
Chromosomes of eukaryotes adopt highly dynamic and complex hierarchical structures in the nucleus. The three-dimensional (3D) organization of chromosomes profoundly affects DNA functions, primarily transcription. During retroviral infection, histone-free viral DNA copy is synthesized from viral genomic RNA. vDNA will u...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1111/mila.12184
Subjectivity in gradable adjectives: The case of tall and heavy
We present an investigation of the ways in which speakers' subjective perspectives are likely to affect the meaning of gradable adjectives like tall or heavy. We present the results of a study showing that people tend to use themselves as a yardstick when ascribing these adjectives to human figures of varied measuremen...
[ "The Human Mind and Its Complexity" ]
10.1117/12.2077090
Integration Of Gaas Based Vcsel Array On Sin Platform With Hcg Reflectors For Wdm Applications
We present a GaAs-based VCSEL structure, BCB bonded to a Si3N4 waveguide circuit, where one DBR is substituted by a free-standing Si3N4 high-contrast-grating (HCG) reflector realized in the Si3N4 waveguide layer. This design enables solutions for on-chip spectroscopic sensing, and the dense integration of 850-nm WDM da...
[ "Systems and Communication Engineering", "Condensed Matter Physics", "Materials Engineering" ]
10.1007/s00285-016-1026-0
A numerical scheme for the early steps of nucleation-aggregation models
In the formation of large clusters out of small particles, the initializing step is called the nucleation, and consists in the spontaneous reaction of agents which aggregate into small and stable polymers called nuclei. After this early step, the polymers are involved in a number of reactions such as polymerization, fr...
[ "Mathematics", "Computer Science and Informatics" ]
10.1098/rsos.140498
Back to Tanganyika: A case of recent trans-species-flock dispersal in East African haplochromine cichlid fishes
The species flocks of cichlid fishes in the East African Great Lakes are the largest vertebrate adaptive radiations in the world and illustrious textbook examples of convergent evolution between independent species assemblages. Although recent studies suggest some degrees of genetic exchange between riverine taxa and t...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
176398
Electron quantum optics in quantum hall edge channels
Quantum effects have been studied on photon propagation in the context of quantum optics since the second half of the last century. In particular, using single photon emitters, fundamental tests of quantum mechanics were explored by manipulating single to few photons in Hanbury-Brown and Twiss and Hong Ou Mandel experi...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
10.1371/journal.pbio.3000679
Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium
Centriolar satellites are dynamic, membraneless granules composed of over 200 proteins. They store, modify, and traffic centrosome and primary cilium proteins, and help to regulate both the biogenesis and some functions of centrosomes and cilium. In most cell types, satellites cluster around the perinuclear centrosome,...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1103/PhysRevX.7.031057
Exploring interacting topological insulators with ultracold atoms: The synthetic creutz-hubbard model
Understanding the robustness of topological phases of matter in the presence of strong interactions and synthesizing novel strongly correlated topological materials lie among the most important and difficult challenges of modern theoretical and experimental physics. In this work, we present a complete theoretical analy...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
W2766599364
Mobile accessibility: natural user interface for motion-impaired users
We designed a natural user interface to access mobile devices for motion-impaired people who cannot use the standard multi-touch input system to work with tablets and smartphones. We detect the head motion of the user by means of the frontal camera and use its position to interact with the mobile device. The purpose of...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
interreg_639
ENHANCEMENT OF CULTURAL HERITAGE THROUGH ENVIRONMENTAL PLANNING AND MANAGEMENT
Cultural Heritage sites located in both rural and urban areas are often facing the dilemma between loss of cultural values and hence loss of identity, due to non-sustainable growth, and economic decline and emigration, due to inappropriate infrastructure and high cost of living (especially, buildings maintenance). CHER...
[ "Human Mobility, Environment, and Space", "The Study of the Human Past", "Studies of Cultures and Arts", "Products and Processes Engineering" ]
10.1111/jgh.12752
Detailed analysis of epithelial-mesenchymal transition and tumor budding identifies predictors of long-term survival in pancreatic ductal adenocarcinoma
Background and Aim: Pancreatic ductal adenocarcinoma (PDAC) is characterized by aggressive biology and poor prognosis even after resection. Long-term survival is very rare and cannot be reliably predicted. Experimental data suggest an important role of epithelial-mesenchymal transition (EMT) in invasion and metastasis ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
W1988171180
Disseminated Staphylococcal Disease in Healthy Children—Experience from Two Tertiary Care Hospitals of West Bengal
To assess the etiology, precipitating factors, treatment and outcome of disseminated staphylococcal disease (DSD) in healthy immunocompetent children.This hospital based observational prospective study was conducted in two tertiary care hospitals of West Bengal, India during the period of March, 2011 through February, ...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1039/C3CC43803A
Robust Molecular Micro Capsules For Encapsulating And Releasing Hydrophilic Contents
The hydrophobic–amphiphilic self-assembly approach has been employed to prepare molecular micro-capsules simply by cooling down an emulsion, in a hot polar solvent medium, of a melted compound having two very well-distinguished units, both with highly non-polar and hydrophobic characteristics. The resulting micro-capsu...
[ "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
W2001676362
Role of high dose rate brachytherapy in the treatment of prostate cancer
High dose rate (HDR) brachytherapy in intermediate and high-risk prostate cancer patients has started in the late eighties in Europe and the United States, as a boost combined with external beam radiation therapy, as an attractive method for dose escalation. The results of the first dose-escalation study performed at W...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
W1922255424
The neoliberal diet and inequality in the United States
This paper discusses increasing differentiation of U.S. dietary components by socioeconomic strata and its health implications. While upper-income groups have had increasing access to higher-quality foods, lower-to-middle-income class diets are heavily focused on "energy-dense" fares. This neoliberal diet is clearly as...
[ "Individuals, Markets and Organisations", "The Social World and Its Interactions", "Human Mobility, Environment, and Space" ]
W2318954487
The use of seismic attenuation for monitoring saturation in hydrocarbon reservoirs
We used a theoretical rock physics forward modelling and synthetic time lapse seismic data to show the possible use of attenuation to monitor hydrocarbon saturation in reservoirs. Given the time variant changes in saturation and the properties of the reservoir rock, the rock physics anelastic model (Mavko et al. 1998) ...
[ "Condensed Matter Physics", "Earth System Science" ]
Q4051093
I FATTORI BIOMEDICI PER LA CERTIFICAZIONE ERGONOMICA DI PRODOTTO
L¿ACQUISIZIONE DEI SERVIZI INNOVATIVI PER SVILUPPARE UNO STRUMENTO (SOFTWARE) CONSENTIRà DI OTTIMIZZARE IN MODO DECISIVO L¿OPERATIVITà IN CAMPO VALUTATIVO PER OFFRIRE AI CLIENTI TUTTE LE INFORMAZIONI NECESSARIE PER MIGLIORARE IL PROCESSO DI PROGETTAZIONE DEI LORO PRODOTTI INTEGRANDO LE LORO CONOSCENZE TECNICHE CON ...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1002/jqs.2663
Revisiting the Faroe Marine Ash Zone III in two Greenland ice cores: Implications for marine-ice correlations
Nineteen new Icelandic tephra layers are identified in NGRIP and NEEM ice spanning Greenland Interstadial-9 (GI-9) and the early phase of GI-8 (∼38 000-40 500 b2k). Fourteen tephras are identified in the NGRIP record and five direct correlatives are identified in NEEM, thus indicating the occurrence of 14 separate volc...
[ "Earth System Science" ]
216701
Miniature beam-driven plasma accelerators
As we push the frontier of particle physics to higher particle energies, conventional accelerator techniques are attaining their limits and new concepts are emerging. The use of an ionized gas —or plasma— circumvents the most significant barrier of conventional techniques by increasing the energy gained per unit length...
[ "Fundamental Constituents of Matter", "Systems and Communication Engineering", "Products and Processes Engineering" ]
724863
Quantitative understanding of target recognition on DNA based on directional zipping processes
In the recent years a number of protein systems have been identified that recognize long (tens of base pairs) DNA sequences and allow flexible programmability of their target specificity. This promoted an enormous range of applications in genome engineering and synthetic biology. This project aims to decipher the mecha...
[ "Physical and Analytical Chemical Sciences", "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
232738
Molecular by-pass therapy for mitochondrial dysfunction
Many eukaryotes, but not the higher metazoans such as vertebrates or arthropods, possess intrinsic by-pass systems that provide alternative routes for electron flow from NADH to oxygen. Whereas the standard mitochondrial OXPHOS system couples electron transport to proton pumping across the inner mitochondrial membrane,...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1038/s41422-020-0370-1
Wnt signaling and Loxl2 promote aggressive osteosarcoma
Osteosarcoma (OS) is the most frequent primary malignant bone tumor in urgent need of better therapies. Using genetically modified mouse models (GEMMs), we demonstrate that Wnt signaling promotes c-Fos-induced OS formation via the actions of the collagen-modifying enzyme Loxl2. c-Fos/AP-1 directly regulates the express...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
10.1103/PhysRevB.90.125125
High-energy collective electronic excitations in layered transition-metal dichalcogenides
We characterize experimentally and theoretically the collective electronic excitations in two prototypical layered transition-metal dichalcogenides, NbSe2 and Cu0. 2NbS2. The energy- and momentum-dependent dynamical structure factor was measured by inelastic x-ray scattering (IXS) spectroscopy and simulated by time-dep...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
10.1080/19475705.2020.1777213
Flood Damage Cost Estimation In 3D Based On An Indicator Modelling Framework
Flooding and other natural disasters pose risks to cities and residential homes, and these are set to increase in the face of climate change. Single-family residential buildings are of particular i. . .
[ "Products and Processes Engineering", "Earth System Science" ]
10.1007/s11537-014-1265-z
Ramanujan complexes and high dimensional expanders
Expander graphs in general, and Ramanujan graphs in particular, have been of great interest in the last four decades with many applications in computer science, combinatorics and even pure mathematics. In these notes we describe various efforts made in recent years to generalize these notions from graphs to higher dime...
[ "Mathematics", "Computer Science and Informatics" ]
10.1177/1545968318820169
Effect Of Specific Over Nonspecific Vr Based Rehabilitation On Poststroke Motor Recovery A Systematic Meta Analysis
Background. Despite the rise of virtual reality (VR)-based interventions in stroke rehabilitation over the past decade, no consensus has been reached on its efficacy. This ostensibly puzzling outco. . .
[ "Neuroscience and Disorders of the Nervous System", "Prevention, Diagnosis and Treatment of Human Diseases", "Computer Science and Informatics" ]
10.1038/s41598-018-34533-1
Design of metalloproteins and novel protein folds using variational autoencoders
The design of novel proteins has many applications but remains an attritional process with success in isolated cases. Meanwhile, deep learning technologies have exploded in popularity in recent years and are increasingly applicable to biology due to the rise in available data. We attempt to link protein design and deep...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Computer Science and Informatics" ]
W1992054668
Investigations of a method for determining pumping speed and sorption capacity of nonevaporable getters based on in situ calibrated throughput
This paper presents a gas-sorption method, based on an in situ calibrated throughput, for characterizing nonevaporable getters (NEGs) of Ti- and Zr-based alloys. The main characteristics of the method are the adjustment of a constant injected gas flow, the prompt calibration of a throughput, and the measurement of an i...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Products and Processes Engineering" ]
W2742251626
Application of different spectrophotometric methods for simultaneous determination of elbasvir and grazoprevir in pharmaceutical preparation
The first three UV spectrophotometric methods have been developed of simultaneous determination of two new FDA approved drugs namely; elbasvir and grazoprevir in their combined pharmaceutical dosage form. These methods include simultaneous equation, partial least squares with and without variable selection procedure (g...
[ "Physical and Analytical Chemical Sciences" ]
10.1038/s41467-017-01773-0
Switching between H- and J-type electronic coupling in single conjugated polymer aggregates
The aggregation of conjugated polymers and electronic coupling of chromophores play a central role in the fundamental understanding of light and charge generation processes. Here we report that the predominant coupling in isolated aggregates of conjugated polymers can be switched reversibly between H-type and J-type co...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
W66444513
Anticipatory Coordination of Electric Vehicle Allocation to Fast Charging Infrastructure
AbstractThe limited range of electric vehicles (EVs) in combination with the limited capacity of current fast charging infrastructure are both causes for a limited adoption of EVs. In order to reduce the general inconvenience that EV users experience when having to wait for available fast charging stations and to lesse...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
W2079193326
Conformal and multi-scale time-domain methods: From tetrahedral mesh to meshless discretisation
Numerical methods applied in Cartesian grids have become workhorses for general purpose time-domain electromagnetic simulations because of their simplicity, efficiency and scalability. Implementations often consider specific treatments for curved and slanted boundaries, as well as sub-cell models and sub-gridding schem...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1007/978-3-319-21626-3
Quantum Modeling Of Complex Molecular Systems
Addressing the Issues of Non-Additivity in the Development of Quantum Chemistry-Grounded Polarizable Molecular Mechanics, Noad Gresh, Krystel El Hage, Elodie Goldwaser, Benoit de Courcy, Robin Chaudret, David Perahia, Christophe Narth, Louis Lagardere, Filippo lipparini, Jean-Philippe Piquemal. - Proton Transfer in Aqu...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Computer Science and Informatics" ]
263760
Family Matters: Intergenerational Influences on Fertility
Why do people have children? Why do they have the number of children they do? These questions are of fundamental importance, but we do not yet have satisfactory answers. I propose to bring an interdisciplinary perspective, involving demography, evolutionary biology, anthropology and psychology, to bear on this topic. T...
[ "Environmental Biology, Ecology and Evolution", "Human Mobility, Environment, and Space" ]
10.1177/0271678X16657094
Nos Knockout Or Inhibition But Not Disrupting Psd 95 Nos Interaction Protect Against Ischemic Brain Damage
Promising results have been reported in preclinical stroke target validation for pharmacological principles that disrupt the N-methyl-D-aspartate receptor-post-synaptic density protein-95-neuronal nitric oxide synthase complex. However, post-synaptic density protein-95 is also coupled to potentially neuroprotective mec...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1039/c4sc02793k
Polycyclic aromatic azomethine ylides: a unique entry to extended polycyclic heteroaromatics
Based on polycyclic aromatic azomethine ylides, a metal-free “cycloaddition-planarization-sequence” is proposed, providing a unique entry to nitrogen-containing polycyclic aromatic hydrocarbons.
[ "Synthetic Chemistry and Materials" ]
10.1145/2591796.2591822
The Asymptotic K Sat Threshold
Since the early 2000s physicists have developed an ingenious but non-rigorous formalism called the cavity method to put forward precise conjectures as to the phase transitions in random constraint satisfaction problems ("CSPs"). The cavity method comes in two versions: the simpler replica symmetric variant, and the mor...
[ "Mathematics", "Computer Science and Informatics" ]
681299
Unfolding the Mechanism of Chromosome Cohesion and Condensation using Single-Molecule Biophysical Approaches
The global folding of the chromosome is mediated by Structural Maintenance of Chromosome (SMC) proteins, which stabilize the higher-order chromatin architecture by bringing distant DNA sequences together. Despite over a decade of work on these systems, their mechanism remains unknown, largely because of difficulty in r...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Physical and Analytical Chemical Sciences" ]
10.1073/pnas.1507459112
Lymphomagenic CARD11/BCL10/MALT1 signaling drives malignant B-cell proliferation via cooperative NF-κB and JNK activation
The aggressive activated B cell-like subtype of diffuse large B-cell lymphoma is characterized by aberrant B-cell receptor (BCR) signaling and constitutive nuclear factor kappa-B (NF-κB) activation, which is required for tumor cell survival. BCR-induced NF-κB activation requires caspase recruitment domain-containing pr...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Cell Biology, Development, Stem Cells and Regeneration", "Prevention, Diagnosis and Treatment of Human Diseases", "Immunity, Infection and Immunotherapy" ]
174139
Novel concept of a modular shelter unit for rapid installation
Urbana de Exteriores is specialised in rehabilitation and conservation of buildings and constructions. Aligned with the use of novel innovative solutions for the constructive sector, the company has decided to focus on the development of SURI as a result of their experience in humanitarian aid after the earthquakes in ...
[ "Products and Processes Engineering", "Human Mobility, Environment, and Space" ]
10.1002/smll.201300378
Dynamic motion of ru-polyoxometalate ions (POMs) on functionalized few-layer graphene
The interaction and stability of Ru4POM on few layer graphene via functional groups is investigated by time-dependent imaging using aberration-corrected transmission electron microscopy. The Ru4POM demonstrates dynamic motion on the graphene surface with its frequency and amplitude of rotation related to the nature of ...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1089/aid.2015.0324
The Neutralizing Antibody Response in an Individual with Triple HIV-1 Infection Remains Directed at the First Infecting Subtype
The effect of serial HIV-1 infection on the development of the broadly neutralizing antibody (bNAb) response was studied in an individual, H01-10366, with a serial HIV-1 superinfection (SI), hence triple infection, and compared with the bNAb response in three superinfected as well as 11 monoinfected men who have had se...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
EP 2010062967 W
COMPOSITION FOR CLEANING WITH ENHANCED ACTIVITY
The present invention relates to a cleaning composition with enhanced cleaning activity and to the use for cleaning of hard and soft surfaces. In particular, the invention relates to a liquid alkaline cleaning composition useful in the cleaning of all kinds of articles or surfaces. The composition for cleaning comprise...
[ "Products and Processes Engineering", "Synthetic Chemistry and Materials" ]
10.1039/c5cc10495e
The Verwey structure of a natural magnetite
Complex charge and orbital molecule order observed in natural magnetite comparable to meteoritic samples is the most complex electronic order known to occur naturally.
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
10.1101/gad.255984.114
Activin/Nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark
Stem cells can self-renew and differentiate into multiple cell types. These characteristics are maintained by the combination of specific signaling pathways and transcription factors that cooperate to establish a unique epigenetic state. Despite the broad interest of these mechanisms, the precise molecular controls by ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W1479125512
Gradual bipolar resistive switching in Ni/Si3N4/n+-Si resistive-switching memory device for high-density integration and low-power applications
Abstract In this work, we report a gradual bipolar resistive switching memory device using Ni/Si 3 N 4 / n + -Si structure. Different reset transitions are observed depending on compliance current ( I COMP ). The reset switching becomes abrupt around I COMP  = 10 mA, while gradual reset switching with fine controllabil...
[ "Condensed Matter Physics", "Materials Engineering" ]
W2065692154
Predicting influenza vaccination uptake among health care workers: What are the key motivators?
Health care worker (HCW) vaccination was critical to protecting HCW during the H1N1 pandemic. However, vaccine uptake rates fell below recommended targets. This study examined motivators and barriers influencing HCW pH1N1 vaccination to identify modifiable factors that can improve influenza vaccine uptake.A cross-secti...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions" ]
948636
Real-time analysis of ribosomal frameshifting and its impact on immunity and disease
The coding region of many genes contains sequence elements that constitute roadblocks during mRNA translation. These roadblocks present problems, but also opportunities for the cell to increase the coding capacity of the genome by so-called programmed ribosome frameshifting (PRF). PRF is a universal gene expression str...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
306274
High-Dimensional Sparse Optimal Control
We are addressing the analysis and numerical methods for the tractable simulation and the optimal control of dynamical systems which are modeling the behavior of a large number N of complex interacting agents described by a large amount of parameters (high-dimension). We are facing fundamental challenges: - Random proj...
[ "Mathematics", "Computer Science and Informatics", "Systems and Communication Engineering" ]
W3094194576
Qualitative Analysis of the Dynamics of a Two-Component Chiral Cosmological Model
We present a qualitative analysis of chiral cosmological model (CCM) dynamics with two scalar fields in the spatially flat Friedman–Robertson–Walker Universe. The asymptotic behavior of chiral models is investigated based on the characteristics of the critical points of the selfinteraction potential and zeros of the me...
[ "Universe Sciences", "Mathematics", "Fundamental Constituents of Matter" ]
10.1074/jbc.M114.561845
Involvement of MicroRNAs in the regulation of muscle wasting during catabolic conditions
Background: MicroRNAs are important modulators of gene expression but their role in the atrophy program and in muscle loss is unknown. Results: miRNA-206 and miRNA-21 are critical for regulation of the atrophy program after denervation. Conclusion: miRNAs are important for the fine-tuning of the atrophy program. Signif...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
185262
Efficient co-electrolyser for efficient renewable energy storage - eco
The overall goal of ECo is to develop and validate a highly efficient co-electrolysis process for conversion of excess renewable electricity into distributable and storable hydrocarbons via simultaneous electrolysis of steam and CO2 through SOEC (Solid Oxide Electrolysis Cells) thus moving the technology from technolog...
[ "Products and Processes Engineering", "Materials Engineering", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Environmental Biology, Ecology and Evolution" ]
10.1016/j.soilbio.2018.07.023
Cellular and non-cellular mineralization of organic carbon in soils with contrasted physicochemical properties
It has been recently demonstrated that soil organic carbon (SOC) mineralization is supported by intracellular respiration of heterotrophic microorganisms and by non-cellular oxidative processes. However, little is known about the prevalence and drivers of non-cellular SOC mineralization among soils. In this study, untr...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
10.1182/blood-2013-06-508267
A Mendelian predisposition to B-cell lymphoma caused by IL-10R deficiency
Monogenic interleukin-10 (IL-10) and IL-10 receptor (IL-10R) deficiencies cause very early onset severe inflammatory bowel disease. Here, we report that 5 patients with an IL-10R1 (n = 1) or IL-10R2 (n = 4) deficiency developed B-cell non-Hodgkin lymphoma between the ages of 5 and 6 years (which was recurrent in 1 pati...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2079629743
Detection of cellular aging in a Galton–Watson process
We consider the bifurcating Markov chain model introduced by Guyon to detect cellular aging from cell lineage. To take into account the possibility for a cell to die, we use an underlying super-critical binary Galton–Watson process to describe the evolution of the cell lineage. We give in this more general framework a ...
[ "Mathematics", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.18054/pb.v118i4.4737
Physiology, phylogeny, and the energetic roots of life
Before the days of molecular phylogenies, the standard way of viewing microbial evolution was as process of physiological evolution: the ordering of the sequence of events in which different pathways that microbes use to harness carbon and energy arose. The physiological view of microbial evolution was, of course, repl...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution" ]
10.1016/j.palaeo.2014.03.012
A new fossil-lagerstätte from the lower eocene of lessini mountains (northern Italy): A multidisciplinary approach
Hemipelagic dark limestones within calciturbiditic deposits at Monte Solane in the western Lessini Mountains of northern Italy yield a fish fauna dominated by stomiiforms. A minor component of the fossil assemblage is represented by a macroalgal non-calcareous flora associated with rarer terrestrial components includin...
[ "Earth System Science", "The Study of the Human Past" ]
10.1007/978-3-319-49996-3_8
Emergent Dynamics Of The Cucker Smale Flocking Model And Its Variants
In this chapter, we present the Cucker–Smale-type flocking models and discuss their mathematical structures and flocking theorems in terms of coupling strength, interaction topologies, and initial data. In 2007, two mathematicians Felipe Cucker and Steve Smale introduced a second-order particle model which resembles Ne...
[ "Mathematics", "Systems and Communication Engineering" ]
10.1007/s10980-020-00988-9
Variation in parasitoid attraction to herbivore-infested plants and alternative host plant cover mediate tritrophic interactions at the landscape scale
Abstract Context Tritrophic interactions may be affected by local factors and the broader landscape context. At small spatial scales, carnivorous enemies of herbivorous insects use herbivore-induced plant volatiles (HIPVs) to find herbivores, but it is unknown whether variation in plant attractiveness due to differenti...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
W1525685977
The evolution of the low-cost airlines in US. The case study on Southwest and Jetblue airlines
The low-cost companies emerged for the first time in the USA airlines’ industry, their model being subsequently taken by the world-wide operators. The purpose of the present paper is to analyze the development stages of the USA low-cost operators’ market, identifying the determinants of the evolution of two major airli...
[ "Individuals, Markets and Organisations" ]
10.1038/s41598-020-58634-y
Inferring quantity and qualities of superimposed reaction rates from single molecule survival time distributions
AbstractActions of molecular species, for example binding of transcription factors to chromatin, may comprise several superimposed reaction pathways. The number and the rate constants of such superimposed reactions can in principle be resolved by inverse Laplace transformation of the corresponding distribution of react...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2237909
Incorporating Hierarchical Dirichlet Process into Tag Topic Model
The Latent Dirichlet Allocation (LDA) is a parametric approach and the number of topics must be predefined. So it is natural to try to capture uncertainty regarding the number of topics. This paper proposes a Tag Hierarchical Dirichlet Process (THDP) that automatically infers the number of topics while also leveraging ...
[ "Computer Science and Informatics" ]
10.1021/la5007132
Self-assembly of polyisoprenoyl gemcitabine conjugates: Influence of supramolecular organization on their biological activity
An amphiphilic prodrug of gemcitabine, a cytidine analogue used clinically against various tumors, had been previously synthesized by covalent coupling to squalene, a natural isoprenoid chain. The resulting bioconjugate self-assembled spontaneously in water as nanoparticles, displaying an impressive activity both in vi...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Synthetic Chemistry and Materials", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2909662126
Preheating Quantification for Smart Hybrid Heat Pumps Considering Uncertainty
The deployment of smart hybrid heat pumps (SHHPs) can introduce considerable benefits to electricity systems via smart switching between electricity and gas while minimizing the total heating cost for each individual customer. In particular, the fully optimized control technology can provide flexible heat that redistri...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
10.1103/PhysRevB.98.075135
Bond disproportionation, charge self-regulation, and ligand holes in s-p and in d -electron ABX3 perovskites by density functional theory
Some ABX3 perovskites exhibit different local environments (DLE) for the same B atoms in the lattice, an effect referred to as disproportionation, distinguishing such compounds from common perovskites that have single local environments (SLE). The basic phenomenology associated with such disproportionation involves the...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1016/j.immuni.2016.08.015
Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species
Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic potential. Multiple DC subsets have been described, and it remains challenging to align them across tissues and species to analyze their function in the absence of macrophage contamination. Here, we provide and validate a univer...
[ "Immunity, Infection and Immunotherapy", "Cell Biology, Development, Stem Cells and Regeneration", "Computer Science and Informatics" ]
W2001707301
Modeling of lightly doped drain and source graphene nanoribbon field effect transistors
Abstract In this paper, to minimize the tunneling leakage current, we propose a graphene nanoribbon (GNR) field effect transistor (FET) using lightly doped drain and source (LDDS) between intrinsic channel region and highly doped source and drain regions. By using a nonequilibrium Green’s function (NEGF) method, the tr...
[ "Condensed Matter Physics", "Systems and Communication Engineering" ]
889448
Controlling ultrafast heat in layered materials
In this project I propose to take advantage of the enormous potential created by the recent material science revolution based on two-dimensional (2D) layered materials, by bringing it to the arena of nanoscale heat transport, where heat transport occurs on ultrafast timescales. This opens up a new research field of con...
[ "Condensed Matter Physics", "Synthetic Chemistry and Materials", "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1007/s40803-017-0065-y
The Strasbourg Court Meets Abusive Constitutionalism: Baka v. Hungary and the Rule of Law
The rise of abusive constitutionalism in Central and Eastern Europe (CEE) has hit the domestic judiciaries particularly hard. Viktor Orbán expanded the size of the Constitutional Court and then packed it, made sure that he can install a new president of the Constitutional Court, ousted the Supreme Court president throu...
[ "Institutions, Governance and Legal Systems" ]
10.1088/1748-0221/13/09/P09005
Optimisation Of The Scintillation Light Collection And Uniformity For The Solid Experiment
This paper presents a comprehensive optimisation study to maximise the light collection efficiency of scintillating cube elements used in the SoLid detector. Very short baseline reactor experiments, like SoLid, look for active to sterile neutrino oscillation signatures in the anti-neutrino energy spectrum as a function...
[ "Fundamental Constituents of Matter", "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
3726691
Twinning towards the russian-armenian university’s scientific excellence and innovation capacity in nanomaterials for quantum information and quantum optics
Quantum Technology (QT) is an emerging field with a heavy volume of investments globally – private (Google, IBM, Toshiba) and public (Canada, U.S., and EU with its 1 billion EUR Quantum Flagship). Among the most evident benefits provided by QT are highly efficient quantum computers decreasing ICT energy consumption and...
[ "Condensed Matter Physics", "Materials Engineering", "Synthetic Chemistry and Materials" ]
W2057249214
Dystocia in Friesian cows and its effects on postpartum reproductive performance and milk production
A total of 1,243 records for 585 dairy Friesian cows from 1997-2004 were used to study the factors affecting dystocia and its effects on reproductive performance and milk production. The overall incidence of dystocia was 6.9%. The percentage of dystocia decreased with increasing live body weight, age, and parity of cow...
[ "Physiology in Health, Disease and Ageing", "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering" ]
223664
Industrial manufacturing of eco-innovative, safe, sustainable functionalised microencapsulated fragrances for fabric softeners
Fabric softeners are the most popular laundry care products after detergents. They keep clothes soft, enhance nice smells while preventing musty odours, extend the life of clothes, reduce the formation of wrinkles and improve endurance ability of clothes against stains. However, existing fabric softeners are usually ...
[ "Products and Processes Engineering", "Materials Engineering", "Synthetic Chemistry and Materials" ]
10.1002/anie.201310380
Enantioselective synthesis of allylboronates and allylic alcohols by copper-catalyzed 1,6-boration
Chiral secondary allylboronates are obtained in high enantioselectivities and 1,6:1,4 ratios by the copper-catalyzed 1,6-boration of electron-deficient dienes with bis(pinacolato)diboron (B2(pin)2). The reactions proceed efficiently using catalyst loadings as low as 0. 0049 mol %. The allylboronates may be oxidized to ...
[ "Synthetic Chemistry and Materials", "Physical and Analytical Chemical Sciences" ]
10.1051/0004-6361/201628676
Herschel Observations Of Edge On Spirals Heroes Iii Dust Energy Balance Study Of Ic 2531
We investigate the dust energy balance for the edge-on galaxy IC 2531, one of the seven galaxies in the HEROES sample. We perform a state-of-the-art radiative transfer modelling based, for the first time, on a set of optical and near-infrared galaxy images. We show that taking into account near-infrared imaging in the ...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
743116
Turning the concept of magnetocaloric cooling on its head
Twenty years of research in magnetocaloric materials has failed to provide the necessary breakthrough that will lead to a commercial realisation of this technology and satisfy the urgent global need for more efficient refrigeration. We strongly believe that this is a result of looking in the wrong direction. The cool i...
[ "Condensed Matter Physics", "Materials Engineering", "Products and Processes Engineering" ]
W1493539209
Mejoramiento en los comportamientos de autocuidado después de una intervención educativa de enfermería con pacientes con falla cardíaca
Objective. To evaluate the improvement in self-care behaviors after a nursing educational intervention in patients with heart failure. Methodology. The study had the participation of 29 patients over 30 years of age, who attended in 2010 the cardiovascular healthcare program of a hospital institution in Medellin (Colom...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
10.1016/j.foreco.2018.10.001
Towards better mapping of forest management patterns: A global allocation approach
Forests provide numerous ecosystem services, such as timber yields, biodiversity protection and climate change mitigation. The type of management has an effect on the provision of these services. Often the demands for these services can lead to conflict – wood harvest can negatively impact biodiversity and climate chan...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Computer Science and Informatics" ]
10.1128/JVI.01601-16
Structure Of Aichi Virus 1 And Its Empty Particle Clues To Kobuvirus Genome Release Mechanism
Aichi virus 1 (AiV-1) is a human pathogen from the Kobuvirus genus of the Picornaviridae family. Worldwide, 80 to 95% of adults have antibodies against the virus. AiV-1 infections are associated wi . . .
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy" ]
10.3390/acoustics2010009
Historical Acoustics: Relationships between People and Sound over Time
The Special Issue “Historical Acoustics: Relationships between People and Sound over Time” was the inaugural collection of the recently established journal “Acoustics (MDPI)”, so it felt appropriate to give it a focus to history, places and events of historical relevance, seeking to explore the origins of acoustics, an...
[ "The Study of the Human Past", "Condensed Matter Physics" ]
W578488647
Advanced placement study guide, Human geography : people, place, and culture, ninth edition
Human Geography gets general readers to think geographically across scale and across a wide range of geographical phenomena and global issues. All concepts and themes are touched on with the historical background one would expect, but also with current examples to make the reading more relevant. The content is written ...
[ "Human Mobility, Environment, and Space" ]
10.1142/S0217751X13501133
Fermions via spinor-valued one-forms
Spinor-valued one-forms (Rarita-Schwinger fields) are normally used in the context of supergravity, where they describe spin 3/2 particles (gravitinos). Indeed, when decomposed into irreducible representations of the Lorentz group such a field contains both a spin 1/2 and a spin 3/2 component, and the Rarita-Schwinger ...
[ "Fundamental Constituents of Matter", "Mathematics" ]
Q2892769
Rui Azevedo Digital Strategy 4.0
The priority objective of the Rui Azevedo Digital Strategy 4.0? project is to define a strategy for the digital promotion of its activity. We want to make Rui Azevedo a reference company in the use of new online trading channels.
[ "Individuals, Markets and Organisations" ]
10.1101/gr.177220.114
Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line
Near-haploid human cell lines are instrumental for genetic screens and genome engineering as gene inactivation is greatly facilitated by the absence of a second gene copy. However, no completely haploid human cell line has been described, hampering the genetic accessibility of a subset of genes. The near-haploid human ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1107/S2059798315022482
Initiating Heavy Atom Based Phasing By Multi Dimensional Molecular Replacement
To obtain an electron-density map from a macromolecular crystal the phase-problem needs to be solved, which often involves the use of heavy-atom derivative crystals and concomitantly the determination of the heavy atom substructure. This is customarily done by direct methods or Patterson-based approaches, which however...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences", "Computer Science and Informatics" ]
W1982690471
Flow and heat transfer characteristics of falling water film on horizontal circular and non-circular cylinders
Abstract This paper presents a two-dimensional CFD study of the falling film evaporation of horizontal tubes with different shapes applied in the seawater desalination. The flow and heat transfer characteristics of the falling water film on one circular tube and two non-circular shaped tubes, a drop-shaped tube and an ...
[ "Condensed Matter Physics", "Products and Processes Engineering" ]
10.1088/1742-6596/1522/1/012023
A Note On The Reconstruction Of A 3D 3C Velocity Field For Box Turbulence
We examine the reconstruction of a three-dimensional three-component (3D-3C) snapshot velocity field in a torus using a denoising method of compressed sensing. Using 30% of the total grid points, we could reconstruct the velocity with a relative error of approximately 10%.
[ "Computer Science and Informatics", "Mathematics" ]
10.1016/j.worlddev.2017.04.003
Indirect Recognition. Frontiers and Territorialization around Mount Halimun-Salak National Park, Indonesia
Government institutions and local people in Indonesia have entrenched, resurrected, and reinvented space through their different territorial and property claims. From colonial times, onward, government institutions have dissolved local political orders and territorialized and reordered spatial frontiers. Local resource...
[ "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
10.1159/000338121
Endoplasmic Reticulum Stress And Inflammation
Endoplasmic reticulum (ER) stress due to the presence of misfolded or unfolded proteins in the ER invokes a fundamental biological response, termed the unfolded protein response (UPR). The UPR is orch
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W1518754995
George Moore: influence and collaboration
Nearly every major figure of his era, writes his biographer Adrian Frazier, worked with Moore, tangled with Moore, took his impression from, or left it on, George Moore. The Anglo-Irish novelist George Moore (1852-1933) espoused multiple identities. An agent provocateur whether as an art critic, novelist, short fiction...
[ "Texts and Concepts", "Studies of Cultures and Arts" ]
10.1016/j.crm.2015.07.001
Exploring the use of seasonal climate forecasts in Europe through expert elicitation
The importance of climate information for decision-making in sectors susceptible to climate variability and change is widely recognised. Advancements in climate science have led to an increased interest in seasonal climate forecasts (SCF) although in Europe very little is known about the practical use of these forecast...
[ "Earth System Science", "Human Mobility, Environment, and Space" ]
10.1007/s10552-014-0420-4
Oral contraceptive use, parity, and constitutional characteristics in soft tissue sarcoma: A Swedish population-based case–control study 1988–2009
Background and methods: The etiology of soft tissue sarcoma is largely unknown. We have studied the effect of hormone related factors on STS in the Swedish population between 1988 and 2009 using a population-based matched case–control design.
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
US 2008/0055217 W
PNEUMATICALLY SELF-REGULATING VALVE
A pneumatic motor that includes a cylinder (42), a piston (48) disposed in the cylinder, and a pneumatically-reset pilot valve (38). In certain embodiments, the pneumatically-reset pilot valve (38) is configured to move to a first position in response to a change in pressure in the cylinder.
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
W2106646559
The World Trade Center disaster: a tragic source of medical advancement
The history of medicine is full of examples of the determination of scientists when faced with public health disasters. As a result of this strength, many tragedies that occurred in the 20th century were followed by important scientific developments. If World War I marked the advent of chemical weapons, it also provide...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing", "Immunity, Infection and Immunotherapy" ]