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2723937
Toward new era of quantum electrical measurements through phase slips
We will exploit new macroscopic quantum phenomena realised in superconducting nanowires made from 2D superconductors to trigger a paradigm change in electrical metrology. Our overall objective is to develop a robust and easy-to-use universal electrical quantum standard on a single chip by utilizing the duality of super...
[ "Condensed Matter Physics", "Systems and Communication Engineering" ]
10.3389/fncel.2014.00287
A simulation study on the effects of dendritic morphology on layer V prefrontal pyramidal cell firing behavior
Pyramidal cells, the most abundant neurons in neocortex, exhibit significant structural variability across different brain areas and layers in different species. Moreover, in response to a somatic step current, these cells display a range of firing behaviors, the most common being (1) repetitive action potentials (Regu...
[ "Neuroscience and Disorders of the Nervous System", "Computer Science and Informatics" ]
10.1186/s40323-016-0078-4
Vademecum-based approach to multi-scale topological material design
The work deals on computational design of structural materials by resorting to computational homogenization and topological optimization techniques. The goal is then to minimize the structural (macro-scale) compliance by appropriately designing the material distribution (microstructure) at a lower scale (micro-scale), ...
[ "Materials Engineering", "Computer Science and Informatics", "Condensed Matter Physics" ]
849841
Resource efficient bio-chemical production and waste treatment
The REBOOT project will create a disruptive wet waste valorisation technology where valuable resources are re-used rather than disposed of while tackling two urgent environmental challenges: nutrient circularity and climate change. Wastewater treatment sludge and manure treatment technologies are currently not satisfac...
[ "Products and Processes Engineering", "Biotechnology and Biosystems Engineering", "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
W2559793906
The Comparative Impact of Pictorial Annotations and Morphological Instruction on Lexical Inferencing of Iranian Intermediate EFL Learners
One of the main ways to acquire unfamiliar words is to make guesses about words meaning. This study investigates the comparative effects of pictorial annotations and morphological instructions on Iranian EFL learners’ lexical inferencing ability. Considering homogeneity issues using PET (Preliminary English Test), the ...
[ "The Human Mind and Its Complexity", "The Social World and Its Interactions" ]
W2166361031
Artificial neural network forward modelling and inversion of electrokinetic logging data
An artificial neural network method is proposed as a computationally economic alternative to numerical simulation by the Biot theory for predicting borehole seismoelectric measurements given a set of formation properties. Borehole seismoelectric measurements are simulated using a finite element forward model, which sol...
[ "Earth System Science", "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.7554/eLife.29944
A new genus of horse from pleistocene North America
The extinct ‘New World stilt-legged’, or NWSL, equids constitute a perplexing group of Pleistocene horses endemic to North America. Their slender distal limb bones resemble those of Asiatic asses, such as the Persian onager. Previous palaeogenetic studies, however, have suggested a closer relationship to caballine hors...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
W1987720974
Development of microsatellite markers for Peristenus digoneutis (Hymenoptera: Braconidae), a key natural enemy of tarnished plant bugs
The introduced European parasitoid Peristenus digoneutis is a key biocontrol agent of lygus bug pests in agricultural crops in the Northeastern USA. Changes in cultural practices and reduction of alfalfa culture have significantly reduced its abundance in its native range from historic levels. Of 48 microsatellite loci...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1016/j.jml.2012.02.007
Cumulative semantic interference is blind to language: Implications for models of bilingual speech production
Several studies have shown that concepts spread activation to words of both of a bilingual's languages. Therefore, a central issue that needs to be clarified is how a bilingual manages to restrict his speech production to a single language. One influential proposal is that when speaking in one language, the other langu...
[ "The Human Mind and Its Complexity" ]
10.1073/pnas.1200161109
Moment-based inference predicts bimodality in transient gene expression
Recent computational studies indicate that the molecular noise of a cellular process may be a rich source of information about process dynamics and parameters. However, accessing this source requires stochastic models that are usually difficult to analyze. Therefore, parameter estimation for stochastic systems using di...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Mathematics", "Integrative Biology: from Genes and Genomes to Systems" ]
interreg_1399
ManuFactUring educaTion and training governance model for IndUstry 4.0 in the Adriatic-Ionian aREa
The challenges brought about by the fourth industrial revolution are at the very heart of the project FUTURE 4.0. The further developmental stage in the organisation and management of the entire value chain process involved in manufacturing industry is radically changing even the concept of enterprise. EUSAIR area soci...
[ "Products and Processes Engineering", "Computer Science and Informatics", "Individuals, Markets and Organisations", "The Social World and Its Interactions" ]
W2433711949
Satellite-Based Offshore Wind Resource Assessment in the Mediterranean Sea
Identification of prominent sea areas for the efficient exploitation of offshore wind energy potential requires primarily the assessment and modeling of several aspects of the long-term wind climate. In this work, the offshore wind speed and wind direction climate of the Mediterranean Sea is analytically described, the...
[ "Earth System Science", "Products and Processes Engineering" ]
10.1145/3025453.3025765
What Is Interaction
The term interaction is field-defining, yet surprisingly confused. This essay discusses what interaction is. We first argue that only few attempts to directly define interaction exist. Nevertheless, we extract from the literature distinct and highly developed concepts, for instance viewing interaction as dialogue, tran...
[ "Computer Science and Informatics", "The Human Mind and Its Complexity" ]
W4281854535
Parâmetros produtivos e genéticos da produção in vitro de embriões Nelore no Estado do Acre
Objetivou-se avaliar dados retrospectivos da produção in vitro de embriões (PIV) em Nelore, no Estado do Acre, a fim de estabelecer parâmetros não genéticos e genéticos. Para tanto, dados de 1292 sessões de aspirações foliculares guiadas por ultra som realizadas em 571 doadoras Nelore, distribuídas em dez fazendas no A...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
629714
Magnetic alignment for high precision 3d assembly
In microelectronics, 3D integration and assembly definitely appears as a very efficient option to achieve highly integrated chips. It offers major benefits such as combining heterogeneous technologies, combining high-performance and low-power chips, increasing data transfer bandwidth in memory above logic circuits, et...
[ "Systems and Communication Engineering", "Materials Engineering" ]
10.1080/23746149.2019.1622451
Advanced Bioengineering Technologies For Preclinical Research
Current in vitro practices must overcome important challenges to compare favorably with human studies. The limited applicability of conventional in vitro assays and strategies can be explained by t. . .
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]
804098
Challenges on the road to genome duplication: Single-molecule approaches to study replisome collisions
Faithful duplication and transmission of genetic and epigenetic information is the most vital cellular function for the preservation and proliferation of life. In cells, this process is conducted by large macromolecular complexes, known as replisomes, that coordinate the sequence of enzymatic events during chromosome d...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W4220790923
Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children
Two thirds of children with tuberculosis have nonsevere disease, which may be treatable with a shorter regimen than the current 6-month regimen.We conducted an open-label, treatment-shortening, noninferiority trial involving children with nonsevere, symptomatic, presumably drug-susceptible, smear-negative tuberculosis ...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Immunity, Infection and Immunotherapy" ]
10.1016/j.jbtep.2019.101514
Combining oxytocin and cognitive bias modification training in a randomized controlled trial: Effects on trust in maternal support
Background and objectives: Research on the social effects of intranasal oxytocin in children is scarce. Oxytocin has been proposed to have clearer beneficial effects when added to social learning paradigms. The current study tested this proposition in middle childhood by assessing effects of cognitive bias modification...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
Q2890868
Liftech – Stärkung der internationalen Position 2017-2019
LIFTECH: Internationalisierungsprojekt zur Konsolidierung der internationalen Präsenz und Erschließung neuer Märkte, die als strategisch und anspruchsvoll gelten, die Exportbasis erhöhen und ein ausgeprägtes Image für die Qualität und Entwicklung innovativer Projekte fördern.
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
W1991334147
MT-OMP for hyperspectral imagery denoising with model parameter estimation
It is extensively accepted that much noise is included in hyperspectral imagery (HSI). Noise removal for HSI is an important but challenging task. Most denoising methods have one or more model parameters. For many algorithms, the denoising performance strongly depends on the values of parameters. In many cases, empiric...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1038/nmat4303
Extreme mobility enhancement of two-dimensional electron gases at oxide interfaces by charge-transfer-induced modulation doping
Two-dimensional electron gases (2DEGs) formed at the interface of insulating complex oxides promise the development of all-oxide electronic devices. These 2DEGs involve many-body interactions that give rise to a variety of physical phenomena such as superconductivity, magnetism, tunable metal-insulator transitions and ...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1038/ncomms2683
VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation
Vascular endothelial growth factor (VEGF) guides the path of new vessel sprouts by inducing VEGF receptor-2 activity in the sprout tip. In the stalk cells of the sprout, VEGF receptor-2 activity is downregulated. Here, we show that VEGF receptor-2 in stalk cells is dephosphorylated by the endothelium-specific vascular ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1002/2014PA002636
High Latitude Forcing Of Diatom Productivity In The Southern Agulhas Plateau During The Past 350 Kyr
The hydrography of the Indian-Atlantic Ocean gateway has been connected to high-latitude climate dynamics by oceanic and atmospheric teleconnections on orbital and suborbital timescales. A wealth of sedimentary records aiming at reconstructing the late Pleistocene paleoceanography around the southern African continent ...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
10.1109/IPFA.2013.6599165
Transverse Domain Wall Formation In A Free Layer A Mechanism For Switching Failure In A Mtj Based Stt Mram
We investigate the switching failure probability in a MTJ-based STT-MRAM as a function of the switching current value and the pulse duration by means of extensive micromagnetic simulations. We analyze a new failure mechanism for switching through the formation and pinning of the transverse domain wall in the free layer...
[ "Condensed Matter Physics", "Systems and Communication Engineering" ]
10.1038/nature14182
Functional organization of excitatory synaptic strength in primary visual cortex
The strength of synaptic connections fundamentally determines how neurons influence each other's firing. Excitatory connection amplitudes between pairs of cortical neurons vary over two orders of magnitude, comprising only very few strong connections among many weaker ones. Although this highly skewed distribution of c...
[ "Neuroscience and Disorders of the Nervous System" ]
10.1017/S0040557417000072
The Sublime And French Seventeenth Century Theories Of The Spectacle Toward An Aesthetic Approach To Performance
Theatre scholars and historians assume too easily that theoretical reflection on the performative qualities of the theatre began only in the eighteenth century. In mid-eighteenth century France, writers and philosophers such as Denis Diderot, Jean le Rond D'Alembert, Jean-Jacques Rousseau, Antoine-Francois Riccoboni, o...
[ "The Study of the Human Past", "Texts and Concepts" ]
10.1073/pnas.1412996112
Strength and duration of perisomatic GABAergic inhibition depend on distance between synaptically connected cells
GABAergic perisoma-inhibiting fast-spiking interneurons (PIIs) effectively control the activity of large neuron populations by their wide axonal arborizations. It is generally assumed that the output of one PII to its target cells is strong and rapid. Here, we show that, unexpectedly, both strength and time course of P...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1038/nature17151
On-surface synthesis of graphene nanoribbons with zigzag edge topology
Graphene-based nanostructures exhibit electronic properties that are not present in extended graphene. For example, quantum confinement in carbon nanotubes and armchair graphene nanoribbons leads to the opening of substantial electronic bandgaps that are directly linked to their structural boundary conditions. Nanostru...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
290911
Variation & the City
VarCity aims to drastically innovate 3D city modeling, moving it away from the traditional, bottom-up Lidar or structure-from-motion pipelines. Not only will large-scale city modeling be automated, but the results will look more realistic, will be more compact and will be semantically structured. Moreover, the dynamics...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1038/NCHEM.2419
Diversification Of Self Replicating Molecules
How new species emerge in nature is still incompletely understood and difficult to study directly. Self-replicating molecules provide a simple model that allows us to capture the fundamental processes that occur in species formation. We have been able to monitor in real time and at a molecular level the diversification...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution" ]
10.1088/2041-8205/760/2/L33
Discovery And Early Multi Wavelength Measurements Of The Energetic Type Ic Supernova Ptf12Gzk A Massive Star Explosion In A Dwarf Host Galaxy
We present the discovery and extensive early-time observations of the Type Ic supernova (SN) PTF12gzk. Our light curves show a rise of 0. 8 mag within 2. 5 hr. Power-law fits (f(t)α(t – t_0)^n ) to these data constrain the explosion date to within one day. We cannot rule out a quadratic fireball model, but higher value...
[ "Universe Sciences" ]
10.1007/s10519-012-9581-7
Genotype by environment interactions in cognitive ability: A survey of 14 studies from four countries covering four age groups
A large part of the variation in cognitive ability is known to be due to genetic factors. Researchers have tried to identify modifiers that influence the heritability of cognitive ability, indicating a genotype by environment interaction (G×E). To date, such modifiers include measured variables like income and socioeco...
[ "Integrative Biology: from Genes and Genomes to Systems", "The Human Mind and Its Complexity" ]
715618
Computer-Assisted Language Comparison: Reconciling Computational and Classical Approaches in Historical Linguistics
By comparing the languages of the world, we gain invaluable insights into human prehistory, predating the appearance of written records by thousands of years. The traditional methods for language comparison are based on manual data inspection. With more and more data available, they reach their practical limits. Comput...
[ "Computer Science and Informatics", "The Human Mind and Its Complexity", "The Study of the Human Past" ]
215704
Accelerators validating antimatter physics
Antiprotons, stored and cooled at low energies in a storage ring or at rest in traps, are highly desirable for the investigation of basic questions on fundamental interactions, the static structure of antiprotonic atoms, CPT tests by high-resolution spectroscopy on antihydrogen, as well as gravity experiments. Antimatt...
[ "Fundamental Constituents of Matter", "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1075/avt.00032.ter
Demonstrative-reinforcer constructions and the syntactic role of deictic features
Abstract In this paper I take Romance demonstrative-reinforcer constructions as a way to test whether the deictic features encoded by demonstrative and locative forms are active in the syntax. From a descriptive point of view, I claim that demonstrative systems can be best accoun...
[ "Texts and Concepts", "The Human Mind and Its Complexity" ]
W2151317726
Ancient Mesopotamian Religion: A Profile of the Healing Goddess
In his introduction to Ancient Mesopotamia, A. L. Oppenheim expressed his doubts about the feasibility to write a systematic account of Mesopotamian religion (1977, p. 172; cf. 1950). Indeed, if we understand religion as the sum of individual, conceptual and social concepts and take into account the nature and the stat...
[ "Texts and Concepts", "The Study of the Human Past", "Studies of Cultures and Arts" ]
10.1038/s41467-019-12390-4
Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs
Spatiotemporal control over engineered tissues is highly desirable for various biomedical applications as it emulates the dynamic behavior of natural tissues. Current spatiotemporal biomaterial functionalization approaches are based on cytotoxic, technically challenging, or non-scalable chemistries, which has hampered ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Materials Engineering" ]
W3085999726
Implicaciones al Sistema de Gestión de Calidad por la rotación de personal en las PYME
The staff turnover is described as dropping out of workers from an organization that is caused by different causes and decisions taken either by employees or by the employer, in this article using as a methodology the analysis of different bibliographic sources associated with this topic and arguing a direct relationsh...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
336084
Urban Waves: evaluating structure vulnerability to tsunami and earthquakes
Exposure to coastal floods across the world is forecast to increase to 150 million people and £20 trillion in assets by 2070 (>9% of projected annual global GDP). In addition to cities, potentially vulnerable assets include key infrastructure such as nuclear power plants and ports: the recent Japan earthquake and tsuna...
[ "Earth System Science", "Products and Processes Engineering" ]
10.1002/aelm.201700477
High-Throughput Multiparametric Screening of Solution Processed Bulk Heterojunction Solar Cells
One of the major bottlenecks in the development of organic photovoltaics is the time needed to evaluate each material system. This time ranges from weeks to months if different variables such as blend composition, thickness, annealing, and additives are to be explored. In this study, the use of lateral gradients is pro...
[ "Condensed Matter Physics", "Materials Engineering", "Synthetic Chemistry and Materials" ]
10.1103/PhysRevB.89.045422
Nonlocal spectroscopy of Andreev bound states
We experimentally investigate Andreev bound states (ABSs) in a carbon nanotube quantum dot (QD) connected to a superconducting Nb lead (S). A weakly coupled normal metal contact acts as a tunnel probe that measures the energy dispersion of the ABSs. Moreover, we study the response of the ABS to nonlocal transport proce...
[ "Condensed Matter Physics", "Fundamental Constituents of Matter" ]
interreg_3106
Capitalisation of the RES projects in the MED area
ENERGY TRANSITION AS A STARTING POINT FOR A RESILIENT TERRITORIAL DEVELOPMENT IN MED AREAClimate Change is one of the most relevant challenges we face globally and especially in the MED Area. Territories will have to establish mechanisms ensuring a more resilient management of the available resources. Energy transition...
[ "Earth System Science", "Human Mobility, Environment, and Space", "Products and Processes Engineering" ]
10.3389/fcell.2020.00069
Cytoskeleton Force Exertion in Bulk Cytoplasm
The microtubule and actin cytoskeletons generate forces essential to position centrosomes, nuclei, and spindles for division plane specification. While the largest body of work has documented force exertion at, or close to the cell surface, mounting evidence suggests that cytoskeletal polymers can also produce signific...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
247283
Flame Aerosol Reactors for Manufacturing of Surface-Functionalized Nanoscale Materials and Devices
Nanotechnology research has been directed mostly to the design and synthesis of (a) materials with passive nanostructures (e.g. coatings, nanoparticles of organics, metals and ceramics) and (b) active devices with nanostructured materials (e.g. transistors, amplifiers, sensors, actuators etc). Little is known, however,...
[ "Materials Engineering", "Synthetic Chemistry and Materials", "Condensed Matter Physics", "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W647634866
The Wall Unit
wall unit is the bastard of the furniture family, I read today in a magazine aspiring to be opinion-making in interior design. I flew into a kind of rage. Who would dare to hierarchize the world of home furnishings, thus demoting the wall unit to the ranks of subpar product on a furniture industry scale? The vitriol of...
[ "Texts and Concepts", "The Human Mind and Its Complexity", "Studies of Cultures and Arts" ]
320774
Nanosized porous molecular metal oxides with functionalizable cavities and soft matter behaviour allow studies of new phenomena
It is generally accepted that nano materials “will revolutionize our industries and our lives” (Nobel laureate R. Smalley). We wish to extend our work on unique metal-oxide nano materials, which offer signposting routes due to their structures/forms – like our worldwide highlighted and used spherical capsules with 20 g...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Materials Engineering" ]
10.1063/1.4824391
Enhanced Conformational Sampling Using Enveloping Distribution Sampling
To lessen the problem of insufficient conformational sampling in biomolecular simulations is still a major challenge in computational biochemistry. In this article, an application of the method of enveloping distribution sampling (EDS) is proposed that addresses this challenge and its sampling efficiency is demonstrate...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1038/s41598-019-38571-1
Skeletal Anomalies in The Neandertal Family of El Sidrón (Spain) Support A Role of Inbreeding in Neandertal Extinction
Neandertals disappeared from the fossil record around 40,000 bp, after a demographic history of small and isolated groups with high but variable levels of inbreeding, and episodes of interbreeding with other Paleolithic hominins. It is reasonable to expect that high levels of endogamy could be expressed in the skeleton...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
10.3847/0004-637X/818/2/175
Forming The Cold Classical Kuiper Belt In A Light Disk
Large Kuiper Belt Objects are conventionally thought to have formed out of a massive planetesimal belt that is a few thousand times its current mass. Such a picture, however, is incompatible with multiple lines of evidence. Here, we present a new model for the conglomeration of Cold Classical Kuiper belt objects, out o...
[ "Universe Sciences" ]
W2942333823
Lessons and Evaluation of a Headway Control Experiment in Washington, D.C.
Headway management can potentially reduce passenger waiting time and on-board crowding on high-frequency services. In this study, a headway control experiment was conducted and evaluated for Washington Metropolitan Area Transit Agency routes 70 and 79 in Washington, D.C. The field experiment is evaluated by performing ...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
W2028881527
Effect of Post-Harvest Fungicides and Disinfestants on the Suppression of Silver Scurf on Potatoes in Storage
Silver scurf of potato, caused by Helminthosporium solani, can be a serious problem of potato tubers sold for table stock. The fungus originates primarily on seed and infects the periderm of daughter tubers, causing unsightly blemishes that reduce tuber quality. Secondary spread occurs in potato storage facilities when...
[ "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering", "Products and Processes Engineering" ]
10.1088/0004-637X/756/2/164
Candels The Evolution Of Galaxy Rest Frame Ultraviolet Colors From Z 8 To 4
We study the evolution of galaxy rest-frame ultraviolet (UV) colors in the epoch 4 3. 5, including 113 at z = 7 to 8. We fit the observed spectral energy distribution to a suite of synthetic stellar population models, and measure the value of the UV spectral slope (beta) from the best-fit model spectrum. The median val...
[ "Universe Sciences" ]
10.1039/c5dt03164h
Tin(ii)-functionalization of the archetypal {P8W48} polyoxotungstate
The synthesis of {SnII8P8W48}, the first example of the archetypal {P8W48}-type polyoxotungstate cluster functionalized with the main group metal ions, elucidates the critical reaction parameters that have to be adjusted to avoid numerous competing side reactions.
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1016/j.chembiol.2014.09.010
Conversion of substrate analogs suggests a michael cyclization in iridoid biosynthesis
The core structure of the iridoid monoterpenes is formed by a unique cyclization reaction. The enzyme that catalyzes this reaction, iridoid synthase, is mechanistically distinct from other terpene cyclases. Here we describe the synthesis of two substrate analogs to probe the mechanism of iridoid synthase. Enzymatic ass...
[ "Synthetic Chemistry and Materials", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
EP 8901515 W
WIND PROTECTION AND/OR SUN PROTECTION DEVICE AND/OR PRIVACY SCREEN
The invention concernes a wind protection, sun protection device and/or privacy screen with a rod structure comprising bars, shaped-section rods or tubes, plus fabric. The rod structure is made up of three main struts (1, 2, 3) which can be secured at an angle to each other and which can be braced with respect to each ...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1016/j.immuni.2015.08.011
BALB/c and C57BL/6 Mice Differ in Polyreactive IgA Abundance, which Impacts the Generation of Antigen-Specific IgA and Microbiota Diversity
The interrelationship between IgAs and microbiota diversity is still unclear. Here we show that BALB/c mice had higher abundance and diversity of IgAs than C57BL/6 mice and that this correlated with increased microbiota diversity. We show that polyreactive IgAs mediated the entrance of non-invasive bacteria to Peyer's ...
[ "Immunity, Infection and Immunotherapy", "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
175044
Actafactors: tumor necrosis factor-based immuno-cytokines with superior therapeutic indexes
Tumor Necrosis Factor (TNF) is a homotrimeric pro-inflammatory cytokine that was originally discovered based on its extraordinary antitumor activity. However, its shock-inducing properties, causing hypotension, leukopenia and multiple organ failure, prevented its systemic use in cancer treatment. With this proof-of-con...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1167/15.14.9
An Unattended Mask Makes An Attended Target Disappear
In pattern masking, the target and mask are presented at the same location and follow one another very closely in time. When the observer attends to the target, he or she must also attend to the mask, as the switching time for attention is quite slow. In a series of experiments, we present mask-target-mask sequences st...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
W4281641682
O ECLÉTICO COMO PATRIMÔNIO:
Pretende-se instigar discussões sobre a relação registrada na história entre o patrimônio nacional, o ecletismo e o modernismo. Partindo de discursos amplamente divulgados, como a crítica do movimento moderno ao ecletismo e as práticas iniciais de preservação oficial do patrimônio, estabelece-se uma relação entre algum...
[ "Texts and Concepts", "The Study of the Human Past", "Studies of Cultures and Arts" ]
W2208200177
Visualization of energy and water consumption and GHG emissions: A case study of a Canadian University Campus
Abstract Campuses, communities, and other building clusters are major users of energy and water and thus can have a significant environmental impact. Frequently, their buildings’ resource consumption is metered to various levels of resolution to attempt to track and reduce it. However, the metering and data logging sys...
[ "Earth System Science", "Products and Processes Engineering" ]
10.1042/bcj20190500
The synthesis of branched-chain fatty acids is limited by enzymatic decarboxylation of ethyl- and methylmalonyl-CoA
AbstractMost fatty acids (FAs) are straight chains and are synthesized by fatty acid synthase (FASN) using acetyl-CoA and malonyl-CoA units. Yet, FASN is known to be promiscuous as it may use methylmalonyl-CoA instead of malonyl-CoA and thereby introduce methyl-branches. We have recently found that the cytosolic enzyme...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences" ]
interreg_445
Know about biodiversity and ecosystems to better protect them together
"This project is part of the plan BIODIVALP": This project aims at improving the knowledge on biodiversity and Alpine ecosystems in a cross-border context. The achievement of this goal revolves around the co-construction of a common list of fauna and floristic species and sharing the methods for monitoring, for invento...
[ "Environmental Biology, Ecology and Evolution", "Human Mobility, Environment, and Space" ]
W2115278932
Usability research of interaction design for e-commerce Website
Interaction design is a new discipline which comes from Human-Computer interaction and includes ergonomics, computer science, engineering, aesthetics, psychology and social sciences. Under the rapid development of computer technology, interaction design for e-commerce website is no longer bound by development of new te...
[ "Computer Science and Informatics", "The Social World and Its Interactions" ]
EP 2005050509 W
DEVICE FOR ADJUSTMENT IN A VEHICLE AND RELATED METHOD
The invention concerns an adjusting device (10) and a method for adjusting a component (11, 40) in particular in a vehicle. Said device comprises at least one mobile component (11, 40), which moves relative to a retaining element (13) through a driving element (24), which comprises an electroactive polymer (EAP) (25).
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1051/0004-6361/201833725
A Nearby Super Luminous Supernova With A Long Pre Maximum Plateau And Strong C Ii Features
Context. Super-luminous supernovae (SLSNe) are rare events defined as being significantly more luminous than normal terminal stellar explosions. The source of the additional power needed to achieve such luminosities is still unclear. Discoveries in the local Universe (i. e. z < 0. 1) are scarce, but afford dense multi...
[ "Universe Sciences" ]
10.1016/j.mee.2011.03.102
Ultra-dense silicon nanowires: A technology, transport and interfaces challenges insight (invited)
We present the integration scheme we have optimized to fabricate very short gate length MOSFETs with 2D and 3D arrays of silicon nanowires (NW) and higk-k/metal gate stacks. Aggressively scaled NWs with sub-5 nm diameters are obtained. In particular, we report a 3D matrices technology with up to 13 levels of stacked si...
[ "Condensed Matter Physics", "Materials Engineering", "Synthetic Chemistry and Materials" ]
258742
Eclipsing binary stars as cutting edge laboratories for astrophysics of stellar structure, stellar evolution and planet formation
Spectroscopic binary stars (SB2s) and in particular spectroscopic eclipsing binaries are one of the most useful objects in astrophysics. Their photometric and spectroscopic observations allow one to determine basic parameters of stars and carry out a wide range of tests of stellar structure, evolution and dynamics. Per...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
10.1007/978-3-319-59050-9_30
Extracting The Groupwise Core Structural Connectivity Network Bridging Statistical And Graph Theoretical Approaches
Finding the common structural brain connectivity network for a given population is an open problem, crucial for current neuro-science. Recent evidence suggests there's a tightly connected network shared between humans. Obtaining this network will, among many advantages , allow us to focus cognitive and clinical analyse...
[ "Neuroscience and Disorders of the Nervous System", "Computer Science and Informatics" ]
W2972028397
Estimación de la Función de Importaciones de Ecuador en el Periodo 1976-2015
During the last years, Ecuador has come presenting a deficit in the Trade balance, due to the excess of imports that has presented the country. Down this context raised the present work investigative so called “Estimation of the function of imports of Ecuador, period 1976 – 2015”, with the intention of estimating an im...
[ "Individuals, Markets and Organisations" ]
10.1002/adma.201402766
Self-supported metallic nanopore arrays with highly oriented nanoporous structures as ideally nanostructured electrodes for supercapacitor applications
Self-supported metallic nanopore arrays with highly oriented nanoporous structures are fabricated and applied as ideally nanostructured electrodes for supercapacitor applications. Their large specific surface area can ensure a high capacitance, and their highly oriented and stable nanoporous structure can facilitate io...
[ "Condensed Matter Physics", "Materials Engineering", "Synthetic Chemistry and Materials" ]
10.1177/0956797612457390
Fictitious Inhibitory Differences
The stop-signal paradigm is a popular method for examining response inhibition and impulse control in psychology, cognitive neuroscience, and clinical domains because it allows the estimation of the covert latency of the stop process: the stop-signal reaction time (SSRT). In three sets of simulations, we examined to wh...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.5194/acp-20-649-2020
Experimental investigation into the volatilities of highly oxygenated organic molecules (HOMs)
Abstract. Secondary organic aerosol (SOA) forms a major part of the tropospheric submicron aerosol. Still, the exact formation mechanisms of SOA have remained elusive. Recently, a newly discovered group of oxidation products of volatile organic compounds (VOCs), highly oxygenated organic molecules (HOMs), have been pro...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
10.1109/TSP.2016.2646663
Performance Limits For Noisy Multimeasurement Vector Problems
Compressed sensing (CS) demonstrates that sparse signals can be estimated from underdetermined linear systems. Distributed CS (DCS) further reduces the number of measurements by considering joint sparsity within signal ensembles. DCS with jointly sparse signals has applications in multisensor acoustic sensing, magnetic...
[ "Mathematics", "Computer Science and Informatics" ]
804051
Low Carbon Action in Ordinary Cities
The challenge of LO-ACT is to enable low carbon urban development in medium and small cities in rapidly urbanising areas in East, Central and West Africa, South Asia and South East Asia. The majority of emissions in the next century will be emitted by infrastructures that are yet to be built, particularly in rapidly ur...
[ "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems", "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
US 0209680 W
METHODS OF DELIVERY OF EXOGENOUS PROTEINS TO THE CYTOSOL AND USES THEREOF
The present invention is directed to a method for delivering exogenous proteins to the cytosol, by binding a target antigen (such as a protein) to a transport factor that contains a fragment of a bipartite protein exotoxin, but not the corresponding protective antigen. Preferably, the target antigen is fused to the tra...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy" ]
interreg_1844
INnovatiVe E-Services for booSting Tourist economy and Multimodal public Transportation
Investment project aims at delivering an e-platform supporting an ecosystem of innovative services, addressing the requirements of citizens, tourists and public transportation service providers, while offering, for the first time, a unified view of the – otherwise – fragmented transportation network between the region ...
[ "Computer Science and Informatics", "Products and Processes Engineering", "Systems and Communication Engineering", "Human Mobility, Environment, and Space" ]
10.1016/j.sbi.2015.12.001
Limited cooperativity in protein folding
Theory and simulations predict that the structural concert of protein folding reactions is relatively low. Experimentally, folding cooperativity has been difficult to study, but in recent years we have witnessed major advances. New analytical procedures in terms of conformational ensembles rather than discrete states, ...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.4319/lom.2013.11.28
Development and deployment of a point-source digital inline holographic microscope for the study of plankton and particles to a depth of 6000 m
A point-source digital inline holographic microscope (DIHM) was designed for the imaging of particles from 50 μm to several millimeters in size. The DIHM operates autonomously without connection to external recording devices or power sources and delivers 4. 2 megapixel images at a rate of approximately 7 images s-1, ea...
[ "Earth System Science", "Systems and Communication Engineering", "Environmental Biology, Ecology and Evolution" ]
259064
Catalysis at the Nanoscale
Is it possible to really 'see' individual molecules in action as they are involved in a chemical reaction at a surface? And can we, in this way, get a complete understanding of reaction mechanisms, at the resolution of atoms? The importance of studying chemical reactions at surfaces has recently been highlighted by Ger...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1144/SP411.13
Geology And Archaeology Submerged Landscapes Of The Continental Shelf An Introduction
Sea-level change has influenced human populations globally since prehistoric times. Even in early phases of cultural development, human populations were faced with marine regression and transgression associated with the glacial–interglacial climatic cycle, amplified by glacio-isostatic adjustments in some regions. Glob...
[ "The Study of the Human Past", "Earth System Science" ]
10.1039/d0ob00407c
Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides
A new α1,4 galactosyltransferase has been characterised and used for the synthesis of natural and non-natural cell surface trisaccharide antigens.
[ "Synthetic Chemistry and Materials", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
2726755
The translational cancer faster forward postdoctoral programme – canfaster-er
CanFaster is a joint venture among industry, health care and academia to enhance and accelerate innovations and clinical implementation within oncology. The mission of CanFaster is to prolong and save lives of cancer patients through integrated development and commercialization/implementation of diagnostic/treatment al...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Integrative Biology: from Genes and Genomes to Systems", "Individuals, Markets and Organisations" ]
W412084290
The effects of joint flight attendant and flight crew CRM training programmes on intergroup teamwork and communication
The aim of this research is to assess and evaluate the effectiveness of Crew Resource Management (CRM) training programmes for enhancing teamwork and cooperation between flight attendants and pilots. CRM programmes have been defined as the use of all available resources to achieve a safe flight (Helmreich, Merritt & Wi...
[ "Systems and Communication Engineering", "The Social World and Its Interactions" ]
3736752
Advanced machine learning for innovative drug discovery
The dramatic increase in using of Artificial Intelligence (AI) and machine learning methods in different fields of science becomes an essential asset in the development of the chemical industry, including pharmaceutical, agro biotech, and other chemical companies. However, the application of AI in these fields is not s...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Computer Science and Informatics", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2059887932
Data Mining for Cyber Security
Cyber security is concerned with protecting computer and network system from corruption due to malicious software including Trojan horses and virus. Security of our network system is becoming imperative as massive sensitive information is transmitted across the network. In this research paper, data mining application f...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
3734473
Quantifying and deploying responsible negative emissions in climate resilient pathways
The quantitative potential, effectiveness and impacts of negative emission technologies and practices (NETPs), particularly taking into account relevant disciplines such as sustainability, socio-political and socio-economic sciences, are not so well understood. Based on a multi-discipline approach, with world-leading e...
[ "Environmental Biology, Ecology and Evolution", "Individuals, Markets and Organisations", "Earth System Science" ]
10.1007/s10886-014-0539-5
Stereoisomeric Analysis of 6,10,14-Trimethylpentadecan-2-ol and the Corresponding Ketone in Wing Extracts from African Bicyclus Butterfly Species
Gas chromatography (GC) and mass spectrometry (MS) were used to determine the stereoisomeric compositions of 6,10,14-trimethylpentadecan-2-ol and 6,10,14-trimethylpentadecan-2-one in wing extracts from 17 Bicyclus butterfly species from different regions of Africa. All samples were purified using solid phase extraction...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Environmental Biology, Ecology and Evolution" ]
US 9006432 W
INSULATED BUILDING BLOCK
An insulated, substantially rectangular building block (10) is disclosed. The block (10) contains two spaced, outer supportive parts (12, 14) which are interlockably connected with each other and which extend along the length of the block; and a curvilinear inner insulating material (16) is present in the space between...
[ "Products and Processes Engineering", "Materials Engineering" ]
883817
Innovative nanostructured pla polymer to expand suitable uses of biodegradable packaging
Bioplastics are an essential part of our efforts to reduce pollution and increase sustainability. Of these, the most ecoefficient bioplastic is PLA as it is biodegradable, requires 50% less energy and produces 10 times less emissions in comparison to standard thermoplastics like PET and PP. Furthermore, as it does not ...
[ "Materials Engineering", "Synthetic Chemistry and Materials", "Products and Processes Engineering" ]
219044
Implementation of the discoveries centre for regenerative and precision medicine, a new centre of excellence in portugal
This proposal is an initiative from 5 top-ranked Portuguese universities including the University of Minho (UMINHO), the University of Porto (UPORTO), the University of Aveiro (UAVR), the University of Lisbon (ULISBOA), the New University of Lisbon (UNL), and a university of research and innovation excellence from the ...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Prevention, Diagnosis and Treatment of Human Diseases", "Physiology in Health, Disease and Ageing" ]
10.1016/j.molonc.2014.05.009
Brain metastasis: New opportunities to tackle therapeutic resistance
Brain metastasis is a devastating complication of cancer with unmet therapeutic needs. The incidence of brain metastasis has been rising in cancer patients and its response to treatment is limited due to the singular characteristics of brain metastasis (i. e. , blood-brain-barrier, immune system, stroma). Despite impro...
[ "Neuroscience and Disorders of the Nervous System", "Prevention, Diagnosis and Treatment of Human Diseases", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy" ]
10.1093/mnras/stz1953
Simulating radial velocity observations of trappist-1 with SPIRou
ABSTRACT We simulate a radial velocity (RV) follow-up of the TRAPPIST-1 system, a faithful representative of M dwarfs hosting transiting Earth-sized exoplanets to be observed with SPIRou in the months to come. We generate an RV curve containing the signature of the seven transiting TRAPPIST-1 planets and a realistic st...
[ "Universe Sciences", "Systems and Communication Engineering" ]
10.1109/TIA.2016.2581154
Harmonic instability analysis of a single-phase grid-connected converter using a harmonic state-space modeling method
The increasing number of renewable energy sources in the distribution grid is becoming a major issue for utility companies since grid-connected converters are operating at different operating points due to the probabilistic characteristics of the renewable energy. Usually, the harmonics and impedance from other renewab...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
101002868
TRansport in the InterioR of the Earth from Modelling and Experiments
Project TRIREME will explore the transport of energy through minerals and melts at the high pressure and temperature conditions of the Earth’s interior, and the consequences for Earth’s evolution and its present dynamics, from the core to the biosphere. Deep transport determines the age and growth behaviour of the inne...
[ "Earth System Science", "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
interreg_1889
IT.inerari E R.ete del R.omanico in CO.rsica S.ardegna T.oscana
The theme of the project ITERR-COST - The Romanesque Routes and network in Corsica, Sardinia, Tuscany, on the promotion, enhancement and management of the assets of the Romanesque Upper Tyrrhenian Sea. The Romanesque is one of the roots of European civilization. Between the eleventh and the thirteenth century, presents...
[ "The Study of the Human Past", "Studies of Cultures and Arts" ]
10.5194/gmd-11-1321-2018
The regional climate model REMO (v2015) coupled with the 1-D freshwater lake model FLake (v1): Fenno-Scandinavian climate and lakes
. The regional climate model REMO was coupled with the FLake lake model to include an interactive treatment of lakes. Using this new version, the Fenno-Scandinavian climate and lake characteristics were studied in a set of 35-year hindcast simulations. Additionally, sensitivity tests related to the parameterization of ...
[ "Earth System Science", "Products and Processes Engineering" ]
10.1136/bmjopen-2015-008808
Heavier smoking may lead to a relative increase in waist circumference: Evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium
Objectives: To investigate, using a Mendelian randomisation approach, whether heavier smoking is associated with a range of regional adiposity phenotypes, in particular those related to abdominal adiposity. Design: Mendelian randomisation meta-analyses using a genetic variant (rs16969968/rs1051730 in the CHRNA5-CHRNA3-...
[ "Physiology in Health, Disease and Ageing", "Integrative Biology: from Genes and Genomes to Systems" ]
EP 2009050654 W
BAG INCLUDING CLOSING PROFILES ACTUATED BY SLIDER
The invention relates to a bag (1) that comprises two substantially parallel sheets (12, 13) defining the main walls thereof, complementary closing profiles (2, 3) respectively attached to said sheets (12, 13), and a slider (5) for actuating the profiles (2, 3) upon opening or closing. The bag is characterised in that ...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1186/s12915-019-0672-2
Metabolic vulnerabilities of metastasizing cancer cells
Most cancer patients die due to metastasis formation. Therefore, understanding, preventing, and treating metastatic cancers is an unmet need. Recent research indicates that cancer cells that undergo metastasis formation have a distinct metabolism that can be targeted. Here, I would like to discuss potential opportuniti...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]