id stringlengths 6 42 | title stringlengths 3 499 | abstract stringlengths 0 6.24k | label listlengths 0 6 |
|---|---|---|---|
US 2006/0032140 W | METHOD AND SYSTEM FOR INTEGRATED ASSET MANAGEMENT UTILIZING MULTI-LEVEL MODELING OF OIL FIELD ASSETS | A method for creating an integrated asset management system for an oilfield, the method including: creating a plurality of models representing asset components each model having more than one levels of detail; connecting the more than one models to communicate with one another to create an integrated asset management s... | [
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
2723607 | Enhancing social cohesion through sharing the cultural heritage of forced migrations | The ambition of the project is to contribute to social cohesion and fight refugee marginalization or exclusion by facilitating the encounters between similar life stories, through the mediation of innovative digital and artistic tools. Based on theories of cultural heritage-making, exposing the commonalities of past an... | [
"The Social World and Its Interactions",
"Studies of Cultures and Arts",
"Computer Science and Informatics"
] |
W2622514874 | Revisiting recency abstraction for JavaScript: towards an intuitive, compositional, and efficient heap abstraction | JavaScript is one of the most widely used programming languages. To understand the behaviors of JavaScript programs and to detect possible errors in them, researchers have developed several static analyzers based on the abstract interpretation framework. However, JavaScript provides various language features that are d... | [
"Computer Science and Informatics"
] |
10.1126/scitranslmed.3009093 | TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis | Genetic variants in the triggering receptor expressed on myeloid cells 2 (TREM2) have been linked to Nasu-Hakola disease, Alzheimer's disease (AD), Parkinson's disease, amyotrophic lateral sclerosis, frontotemporal dementia (FTD), and FTD-like syndrome without bone involvement. TREM2 is an innate immune receptor prefer... | [
"Neuroscience and Disorders of the Nervous System",
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1007/s00062-017-0658-9 | High Isotropic Resolution T2 Mapping of the Lumbosacral Plexus with T2-Prepared 3D Turbo Spin Echo | Purpose: Isotropic high-resolution three-dimensional (3D) magnetic resonance neurography (MRN) is increasingly used to depict even small and highly oblique nerves of the lumbosacral plexus (LSP). The present study introduces a T2 mapping sequence (T2-prepared 3D turbo spin echo) that is B1-insensitive and enables quant... | [
"Physical and Analytical Chemical Sciences",
"Neuroscience and Disorders of the Nervous System"
] |
10.1038/nrn.2016.162 | Structural plasticity and reorganisation in chronic pain | Chronic pain is not simply a temporal continuum of acute pain. Studies on functional plasticity in neural circuits of pain have provided mechanistic insights and linked various modulatory factors to a change in perception and behaviour. However, plasticity also occurs in the context of structural remodelling and reorga... | [
"Neuroscience and Disorders of the Nervous System",
"Physiology in Health, Disease and Ageing",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
interreg_2421 | Mines of Mountains | The territory of the project is characterized by an important natural heritage, and is considered as a mountain area. That’s why it’s necessary to bring a particular attention in order to limit the depopulation of these marginal areas and contain climate changes, witch impact it deeply. The main economic activity pass ... | [
"Earth System Science",
"Human Mobility, Environment, and Space",
"The Study of the Human Past"
] |
10.3791/55221 | 3D Magnetic Stem Cell Aggregation And Bioreactor Maturation For Cartilage Regeneration | Cartilage engineering remains a challenge due to the difficulties in creating an in vitro functional implant similar to the native tissue. An approach recently explored for the development of autologous replacements involves the differentiation of stem cells into chondrocytes. To initiate this chondrogenesis, a degree ... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Materials Engineering",
"Biotechnology and Biosystems Engineering"
] |
885336 | Smart ordering plan as a service | Knowing how much to order and when is a longstanding industrial problem called order planning. The 2 main approaches are:
1. Upfront ordering. Allows capturing quantity discounts and simplifying operations, but causes high inventory costs (e.g. space, amortisation).
2. Just-in-time ordering. Minimises inventory costs,... | [
"Products and Processes Engineering",
"Computer Science and Informatics"
] |
185333 | Novel system for surface inspection and quality control for steel industries. | European and global steel industry are facing several challenges, including meeting the high international quality standards.
ISEND is a SME founded in 2006 and a acknowledged worldwide expert in industrial Non Destructive Test (NDT) systems that is participated by the Venture Capital ”Sodical” to support its intern... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
10.1039/b912997a | Zeolitic imidazole frameworks: Structural and energetics trends compared with their zeolite analogues | We use periodic DFT calculations to compute the total energy of known zeolitic imidazole frameworks (ZIFs) together with those of hypothetical porous ZIFs. We show that the total energy of ZIFs decreases with increasing density, in a similar fashion to the alumino-silicate zeolites, but with a more complex energy lands... | [
"Physical and Analytical Chemical Sciences",
"Materials Engineering"
] |
10.1109/APEC.2017.7931161 | Modulation Strategy For Highly Reliable Cascade H Bridge Inverter Based On Discontinuous Pwm | The Cascaded H-Bridge (CHB) topology is widely employed in high power and high voltage applications due to advantages of the low dv/dt, the low EMI noise, and the low filter inductance. An issue of this modular system is the possible unequal thermal stress of the power semiconductors in the cells, which is affecting th... | [
"Systems and Communication Engineering",
"Products and Processes Engineering"
] |
W2040240485 | Percutaneous Nephrolithotomy in Obese Patients: Comparison Between the Prone and Total Supine Position | Percutaneous nephrolithotomy (PCNL) can be performed in the prone or in the supine position. Comparisons between the two techniques in obese patients are rare in the current literature.The records of obese patients (body mass index >30) who underwent PCNL in the prone or complete supine positions were reviewed. All pat... | [
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1007/s00221-011-2578-2 | Visual experience and blindsight: A methodological review | Blindsight is classically defined as residual visual capacity, e. g. , to detect and identify visual stimuli, in the total absence of perceptual awareness following lesions to V1. However, whereas most experiments have investigated what blindsight patients can and cannot do, the literature contains several, often contr... | [
"Neuroscience and Disorders of the Nervous System"
] |
10.1038/s41598-017-07497-x | Ndrg1 promotes adipocyte differentiation and sustains their function | Adipocytes play a central role in maintaining metabolic homeostasis in the body. Differentiation of adipocyte precursor cells requires the transcriptional activity of peroxisome proliferator-activated receptor-γ (Pparγ) and CCAAT/enhancer binding proteins (C/Ebps). Transcriptional activity is regulated by signaling mod... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
677623 | Regulation of lymphocyte biology by ubiquitin and ubiquitin like modifiers | T lymphocytes are key cells of the adaptive immune system that protect us against pathogens and malignant cells. T cell activation and differentiation are tightly controlled processes and deregulation can result in lymphomas, autoimmunity and inflammation. Hence, the biochemical events regulating lymphocyte biology hav... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.15252/embj.201899852 | Bacterial killing by complement requires membrane attack complex formation via surface-bound C5 convertases | The immune system kills bacteria by the formation of lytic membrane attack complexes (MACs), triggered when complement enzymes cleave C5. At present, it is not understood how the MAC perturbs the composite cell envelope of Gram-negative bacteria. Here, we show that the role of C5 convertase enzymes in MAC assembly exte... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1117/12.896471 | Nanowire Based Heterostructures Fundamental Properties And Applications | In this paper the fundamental properties of heterostructures based on semiconductor nanowires synthesized with molecular beam epitaxy are reviewed. Special focus is given on surface passivation mechanisms with radial epitaxial passivation shells. The growth of radial p-i-n junctions in GaAs nanowires is discussed. Char... | [
"Condensed Matter Physics",
"Synthetic Chemistry and Materials",
"Materials Engineering"
] |
3725781 | Topological quantum gas microsope | In this project I will study the properties of interacting topological insulators using ultracold atoms in optical lattices. To this aim, I will build the first bosonic quantum gas microscope that allows single site resolution in combination with excellent control of atomic interactions. This project will be able to d... | [
"Condensed Matter Physics",
"Fundamental Constituents of Matter"
] |
10.1051/0004-6361/201116481 | Planck Early Results Xxii The Submillimetre Properties Of A Sample Of Galactic Cold Clumps | We perform a detailed investigation of sources from the Cold Cores Catalogue of Planck Objects (C3PO). Our goal is to probe the reliability of the detections, validate the separation between warm and cold dust emission components, provide the first glimpse at the nature, internal morphology and physical characterictics... | [
"Universe Sciences"
] |
10.1145/3306346.3322981 | Volume Aware Design Of Composite Molds | We propose a novel technique for the automatic design of molds to cast highly complex shapes. The technique generates composite, two-piece molds. Each mold piece is made up of a hard plastic shell and a flexible silicone part. Thanks to the thin, soft, and smartly shaped silicone part, which is kept in place by a hard ... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
10.1021/ci400354b | Functional motions modulating VanA ligand binding unraveled by self-organizing maps | The VanA d-Ala:d-Lac ligase is a key enzyme in the emergence of high level resistance to vancomycin in Enterococcus species and methicillin-resistant Staphylococcus aureus. It catalyzes the formation of d-Ala-d-Lac instead of the vancomycin target, d-Ala-d-Ala, leading to the production of modified, low vancomycin bind... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Physical and Analytical Chemical Sciences",
"Computer Science and Informatics",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
W1972414445 | Early pregnancy metabolite profiling discovers a potential biomarker for the subsequent development of gestational diabetes mellitus | Current early pregnancy screening tools to identify women at risk of developing gestational diabetes mellitus lack both specificity and sensitivity. As a result, the foetus and mother are often subjected to insult during disease progression, prior to diagnosis and treatment in later pregnancy. Metabolomics is an analyt... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Physical and Analytical Chemical Sciences"
] |
10.1371/journal.pone.0018901 | Collective irrationality and positive feedback | Recent experiments on ants and slime moulds have assessed the degree to which they make rational decisions when presented with a number of alternative food sources or shelter. Ants and slime moulds are just two examples of a wide range of species and biological processes that use positive feedback mechanisms to reach d... | [
"Mathematics",
"Environmental Biology, Ecology and Evolution"
] |
10.1109/ICST.2017.43 | Timed K Tail Automatic Inference Of Timed Automata | Accurate and up-to-date models describing the behavior of software systems are seldom available in practice. To address this issue, software engineers may use specification mining techniques, which can automatically derive models that capture the behavior of the system under analysis. So far, most specification mining ... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
10.1182/bloodadvances.2018023986 | HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells | Identification of determinants of fate choices in hematopoietic stem cells (HSCs) is essential to improve the clinical use of HSCs and to enhance our understanding of the biology of normal and malignant hematopoiesis. Here, we show that high-mobility group AT hook 2 (HMGA2), a nonhistone chromosomal-binding protein, is... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1186/s12862-018-1279-x | Mosaic mitochondrial-plastid insertions into the nuclear genome show evidence of both non-homologous end joining and homologous recombination | Background: Mitochondrial and plastid DNA fragments are continuously transferred into eukaryotic nuclear genomes, giving rise to nuclear copies of mitochondrial DNA (numts) and nuclear copies of plastid DNA (nupts). Numts and nupts are classified as simple if they are composed of a single organelle fragment or as compl... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
175104 | Open payments eco-system | The aim is to enable the widespread development of innovative payment applications with the active involvement of financial institutions (e.g. banks) providing supporting transaction services by creating an Open Payments Eco-system (OPE). The OPE is the critical step in widening access to payment services and to alter... | [
"Computer Science and Informatics",
"Individuals, Markets and Organisations"
] |
10.4171/JEMS/257 | Presentations Of Finite Simple Groups A Computational Approach | All nonabelian finite simple groups of rank $n$ over a field of size $q$, with the possible exception of the Ree groups $^2G_2(3^{2e+1})$, have presentations with at most $80 $ relations and bit-length $O(\log n +\log q)$. Moreover, $A_n$ and $S_n$ have presentations with 3 generators$,$ 7 relations and bit-length $O(\... | [
"Mathematics",
"Computer Science and Informatics"
] |
10.1016/j.scriptamat.2017.06.016 | Ultra-low-angle boundary networks within recrystallizing grains | We present direct evidence of a network of well-defined ultra-low-angle boundaries in bulk recrystallizing grains of 99. 5% pure aluminium (AA1050) by means of a new, three-dimensional X-ray mapping technique; dark-field X-ray microscopy. These boundaries separate lattice orientation differences on the order of 0. 05° ... | [
"Condensed Matter Physics",
"Materials Engineering"
] |
10.1101/gad.290924.116 | Essential role for centromeric factors following p53 loss and oncogenic transformation | In mammals, centromere definition involves the histone variant CENP-A (centromere protein A), deposited by its chaperone, HJURP (Holliday junction recognition protein). Alterations in this process impair chromosome segregation and genome stability, which are also compromised by p53 inactivation in cancer. Here we found... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
10.1242/dev.112979 | Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells | The development of the central nervous system is known to result from two sequential events. First, an inductive event of the mesoderm on the overlying ectoderm that generates a neural plate that, after rolling into a neural tube, acts as the main source of neural progenitors. Second, the axial regionalization of the n... | [
"Cell Biology, Development, Stem Cells and Regeneration",
"Neuroscience and Disorders of the Nervous System"
] |
949730 | Artificial quantum materials with photons: many-body physics and topology | Physical systems featuring strong electronic correlations exhibit fascinating phenomena, as exemplified by high-Tc superconductivity, quantum magnetism or fractional quantum Hall physics. Inspired by these effects, new ideas have emerged to harness strongly correlated phases in artificial quantum materials, and use the... | [
"Condensed Matter Physics",
"Synthetic Chemistry and Materials",
"Physical and Analytical Chemical Sciences"
] |
714023 | Cracking the epitranscriptome | Over 100 types of distinct modifications are catalyzed on RNA molecules post-transcriptionally. In an analogous manner to well-studied chemical modifications on proteins or DNA, modifications on RNA - and particularly on mRNA - harbor the exciting potential of regulating the complex and interlinked life cycle of these ... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
W2072874994 | Global distribution of Fusarium graminearum, F. asiaticum and F. boothii from wheat in relation to climate | Species of Fusarium that have been segregated from F. graminearum have restricted geographic ranges and it has been suggested that this is due to climate, especially for F. asiaticum. Climate envelope modelling with BIOCLIM was used to quantify the differences in climatic range for F. graminearum, F. asiaticum and F. b... | [
"Earth System Science",
"Environmental Biology, Ecology and Evolution"
] |
290876 | Ultrafast Quantum Physics in Amplitude and Phase | Ultrafast phenomena related to and/or accessible only via the absolute temporal phase of electronic, vibrational and spin coherent excitations in condensed matter are studied via electromagnetic transients in the multi-terahertz regime. The project also includes innovative aspects of quantum optics, femtosecond lasers ... | [
"Condensed Matter Physics",
"Fundamental Constituents of Matter",
"Physical and Analytical Chemical Sciences"
] |
US 2017/0018861 W | NARROW BAND SYNCHRONIZATION SIGNAL | In order to address the needs of narrow band communication, eNB-based processing and/or UE-based processing is provided to achieve robust detection of cell ID and SFN timing location using NB-SSS. A base station constructs a NB-SSS signal using a root index of a Zadoff-Chu (ZC) sequence, a scrambling code, a cyclic shi... | [
"Systems and Communication Engineering",
"Computer Science and Informatics"
] |
Q82205 | Realizzazione di un prodotto innovativo basato sui risultati delle opere di R & S. | Sa 42799(2015/X) L'oggetto del progetto è l'attuazione dei risultati dei lavori di R & S sotto forma di una nuova griglia una tantum. L'implementazione del progetto consentirà di ampliare l'offerta di prodotti di Grill-Impex nell'area della griglia una tantum con parametri ad alte prestazioni, ambientali e di promozion... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
986689 | Mechanism of atp dependent chromatin modelling and editing by ino80 remodellers | Nucleosomes, ~147 base pairs of DNA wrapped around an histone protein octamer, package and protect nuclear DNA but also carry important biological information. The position and composition of nucleosomes along chromosomal DNA is a key element of defining the state and identity of a cell. Chromatin remodellers are ATP d... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Cell Biology, Development, Stem Cells and Regeneration"
] |
754365 | New Nuclear Medicine Imaging Radiotracer 64Cu(II) for diagnosing Hypoxia Conditions Based on the Cellular Copper Cycle | Imaging of hypoxia is important in many disease states in oncology, cardiology, and neurology. Hypoxia is a common condition encountered within the tumour microenvironment that drives proliferation, angiogenesis, and resistance to therapy. Despite on-going efforts to identify hypoxia, until now there is no clinically a... | [
"Prevention, Diagnosis and Treatment of Human Diseases",
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
3729460 | Readout scheme for solid-state nuclear clock | The low-energy excited state of the Thorium-229 (229Th) nucleus has fascinated researchers for decades. With excitation energy of only a few eV, it is the only known nuclear isomeric state accessible to laser manipulation. This system opens up many novel applications, ranging from tests of variations of the fundamental... | [
"Fundamental Constituents of Matter",
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
W2588915132 | InterAKT: A mobile augmented reality browser for geo-social mashups | Current Mobile Augmented Reality (AR) browsers do not reflect users' immediate contexts and lack support for contextual interaction. Such limitations turn users away from the experience, even those who are genuinely interested in the technology. Mobile AR needs a serious move towards a better experience driven by user ... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
W880397381 | An FPT algorithm for the vertex cover P4 problem | A subset F of vertices of a graph G is called a vertex cover P t ( V C P t ) set if every path of order t in G contains at least one vertex from F . The vertex cover P t ( V C P t ) problem is to find a minimum V C P t set in a graph. The V C P t problem is NP-complete for any integer t ≥ 2 . In this paper, we restrict... | [
"Mathematics",
"Computer Science and Informatics"
] |
890690 | Harmonised building information speedway for energy-efficient renovation | ‘BIM for renovation of existing residential building stock’ has been proven viable in innovative pilot projects by the members of BIM-SPEED consortium, among others in H2020 Smart Cities. The mission of BIM-SPEED is to take ‘BIM for renovation’ to a deep renovation level for at least 60% energy saving, and to accelerat... | [
"Products and Processes Engineering",
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
10.1002/anie.201502737 | Synthesis and EPR/UV/Vis-NIR Spectroelectrochemical Investigation of a Persistent Phosphanyl Radical Dication | The reaction of the bis(imidazoliumyl)-substituted PIcation [(2-ImDipp)P(4-ImDipp)]+(10+) (2-Im=imidazolium-2-yl; 4-Im=imidazolium-4-yl; Dipp=2,6-di-isopropylphenyl) with trifluoromethanesulfonic acid (HOTf) or methyl trifluoromethylsulfonate (MeOTf) yields the corresponding protonated [(2-ImDipp)PH(4-ImDipp)]2+(112+) ... | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
EP 2006009646 W | NON-FLUORESCENT ENERGY TRANSFER | The present invention relates generally to the transfer of non-fluorescent energy between donor and acceptor moieties. In certain embodiments, the invention provides biomolecules that include substantially non-fluorescent donor moieties. Processes involving these donor moieties typically entail reduced background fluor... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1073/pnas.1818599116 | Airborne host–plant manipulation by whiteflies via an inducible blend of plant volatiles | The whitefly Bemisia tabaci is one of the world’s most important invasive crop pests, possibly because it manipulates plant defense signaling. Upon infestation by whiteflies, plants mobilize salicylic acid (SA)-dependent defenses, which mainly target pathogens. In contrast, jasmonic acid (JA)-dependent defenses are gra... | [
"Environmental Biology, Ecology and Evolution",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1051/0004-6361/201935603 | Alma View Of The 12C 13C Isotopic Ratio In Starburst Galaxies | We derive molecular-gas-phase C-12/C-13 isotope ratios for the central few hundred parsecs of the three nearby starburst galaxies NGC 253, NGC 1068, and NGC 4945 making use of the lambda similar to 3 mm (CN)-C-12 and (CNN)-C-13= 1-0 lines in the ALMA Band 3. The C-12/C-13 isotopic ratios derived from the ratios of thes... | [
"Universe Sciences",
"Physical and Analytical Chemical Sciences"
] |
10.1007/978-3-642-19835-9_11 | Quantitative Multi Objective Verification For Probabilistic Systems | We present a verification framework for analysing multiple quantitative objectives of systems that exhibit both nondeterministic and stochastic behaviour. These systems are modelled as probabilistic automata, enriched with cost or reward structures that capture, for example, energy usage or performance metrics. Quantit... | [
"Computer Science and Informatics",
"Systems and Communication Engineering"
] |
10.1038/s41598-018-37233-y | Identification of Thermus aquaticus DNA polymerase variants with increased mismatch discrimination and reverse transcriptase activity from a smart enzyme mutant library | DNA polymerases the key enzymes for several biotechnological applications. Obviously, nature has not evolved these enzymes to be compatible with applications in biotechnology. Thus, engineering of a natural scaffold of DNA polymerases may lead to enzymes improved for several applications. Here, we investigated a two-st... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Biotechnology and Biosystems Engineering"
] |
10.1016/j.gca.2013.01.005 | Iron and manganese shuttles control the formation of authigenic phosphorus minerals in the euxinic basins of the Baltic Sea | Microanalysis of epoxy resin-embedded sediments is used to demonstrate the presence of authigenic iron (Fe) (II) phosphates and manganese (Mn)-calcium (Ca)-carbonate-phosphates in the deep euxinic basins of the Baltic Sea. These minerals constitute major burial phases of phosphorus (P) in this area, elevating the total... | [
"Earth System Science",
"Physical and Analytical Chemical Sciences"
] |
10.1038/nrmicro.2016.190 | Cyclic di-GMP: Second messenger extraordinaire | Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di-GMP). Known since the late 1980s, it is now recognized as a near-ubiquitous second messenger that coordinates diverse aspects of bacteria... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1109/TIE.2019.2908593 | Sampling Time Harmonic Control For Cascaded H Bridge Converters With Thermal Control | Cascaded H-bridge converter (CHB) is a multilevel topology that is a well-suited solution for multiple applications such as flexible ac transmission systems or motor drives. This paper is focused on a CHB where the cells present an aging mismatch. This can be caused by the maintenance operation which forces the replace... | [
"Systems and Communication Engineering"
] |
2720680 | Knowledge graphs at scale | Knowledge graphs (KGs) are a flexible knowledge representation paradigm intended to allow knowledge to be consumed by humans and machines. Hence, they are regarded as a key enabler for a number of technologies including question answering, personal assistants and artificial intelligence across all sectors including Ind... | [
"Computer Science and Informatics",
"Institutions, Governance and Legal Systems"
] |
10.1016/j.semcdb.2015.09.018 | Mutational and network level mechanisms underlying resistance to anti-cancer kinase inhibitors | Tyrosine-specific and other protein kinases are embedded in signaling networks critical for progression of tumors of all types. Hence, kinase inhibitors have nucleated a major arm of personalized cancer therapy. Unfortunately, almost all kinase inhibitors evoke resistance within a year or two, due to secondary mutation... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
225219 | Redtadf | Adachis pioneering report in 2012 describing TADF emitters based on CDCBs resulted in a paradigm shift in emitter design within the OLED community. Within just five years, highly efficient blue and green purely organic TADF OLEDs have been developed, achieving maximum EQEs exceeding 30%. This means that performance wis... | [
"Synthetic Chemistry and Materials",
"Physical and Analytical Chemical Sciences",
"Materials Engineering"
] |
10.1162/jocn_a_01109 | Major thought restructuring: The roles of different prefrontal cortical regions | An important question for understanding the neural basis of problem solving is whether the regions of human prefrontal cortices play qualitatively different roles in the major cognitive restructuring required to solve difficult problems. However, investigating this question using neuroimaging faces a major dilemma: eit... | [
"Neuroscience and Disorders of the Nervous System",
"The Human Mind and Its Complexity"
] |
10.1038/pr.2014.204 | Maternal LC-PUFA status during pregnancy and child problem behavior: The Generation R Study | Background:Omega 3 (n-3) and 6 (n-6) long-chain polyunsaturated fatty acids (LC-PUFAs) and the n-3:n-6 ratio are important for brain development. Whether maternal LC-PUFA status during pregnancy affects risk of problem behavior in later childhood is unclear. Methods:Within a population-based cohort, we measured materna... | [
"Neuroscience and Disorders of the Nervous System",
"Physiology in Health, Disease and Ageing",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
10.1057/cep.2014.31 | Home ownership and support for government redistribution | In this article, we investigate the relationship between home ownership and support for redistribution in 24 European countries, integrating research on housing regimes and welfare attitudes. We improve upon earlier research by taking into account within-group heterogeneity of owners and tenants, by elaborating on soci... | [
"The Social World and Its Interactions",
"Individuals, Markets and Organisations"
] |
1262366 | Production and deploying of high purity lignin and affordable platform chemicals through wood-based sugars | The objective of the SWEETWOODS project is to demonstrate on an industrial level successful and profitable production of high purity lignin as well as C5 and C6 carbohydrates from hardwood by establishing a biorefinery having throughput capacity 80 bdton/day. Unlike existing biorefinery concepts, SWEETWOODS plant utili... | [
"Products and Processes Engineering",
"Materials Engineering",
"Biotechnology and Biosystems Engineering"
] |
US 0027238 W | LOCK SYSTEM FOR SHED | A lock system for a shed (A) having a crossbar (30) which is inserted through an opening in a side wall of the shed (A) through guides (40) mounted on the rear of the front wall and the doors of the shed (A) secured by a lock. The crossbar (30) is a solid, elongated rod (32) with a first lock plate (34) projecting from... | [
"Products and Processes Engineering"
] |
10.3182/20120711-3-BE-2027.00125 | How Effective Is The Nuclear Norm Heuristic In Solving Data Approximation Problems | Abstract The question in the title is answered empirically by solving instances of three classical problems: fitting a straight line to data, fitting a real exponent to data, and system identification in the errors-in-variables setting. The results show that the nuclear norm heuristic performs worse than alternative pr... | [
"Mathematics",
"Computer Science and Informatics"
] |
3739292 | From demos to ethnos: popular revolt and elite transformation in montenegro's anti-bureaucratic revolution (1988–1990) | With populism, ethnonationalism, and right-wing radicalism on the rise around the globe, the analysis of the Anti-Bureaucratic Revolution in Montenegro (1988–1990) provides unique empirical material to understand how and why an inclusive and tolerant society (demos) can be rapidly transformed into one based on a more e... | [
"The Study of the Human Past",
"Institutions, Governance and Legal Systems",
"The Social World and Its Interactions"
] |
10.1021/ct3007502 | Protein field effect on the dark state of 11- cis retinal in rhodopsin by quantum monte carlo/molecular mechanics | The accurate determination of the geometrical details of the dark state of 11-cis retinal in rhodopsin represents a fundamental step for the rationalization of the protein role in the optical spectral tuning in the vision mechanism. We have calculated geometries of the full retinal protonated Schiff base chromophore in... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
222674 | Damping device to solve the pantograph-line capture problems, especially for the eu high-speed railways lines | Officina Fratelli Bertolotti S.p.A. was founded in 1901 as a small workshop that was working as blacksmith. From 1920 it specialised in special iron carpentry and in the post-war period it becomes a modern industry thanks to the acquisition of customers in the industry ""Electricity transmission"". Today the company br... | [
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
10.2136/vzj2018.03.0044 | Noninvasive imaging of processes in natural porous media: From pore to field scale | Noninvasive, high-resolution imaging techniques are important for visualizing water flow and transport processes in soils, which are natural porous media. They are a key to understanding effects such as crop production, water resource restoration, CO2 sequestration, or the transport and fate of pollutants. During the l... | [
"Physical and Analytical Chemical Sciences",
"Earth System Science"
] |
311335 | Next generation sequencing for detection of human primary immunodeficiency syndromes characterized by impaired cytotoxic lymphocyte function | Human primary immunodeficiencies affecting cytotoxic lymphocyte function are associated with high morbidity and mortality. They often present as hyperinflammatory syndromes triggered by viral infections, hematological malignancies, or systemic autoimmunity. Although recent advances have provided molecular diagnoses for... | [
"Immunity, Infection and Immunotherapy",
"Integrative Biology: from Genes and Genomes to Systems",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
10.1039/C4RA07304E | Acetylene Bridged Dyes With High Open Circuit Potential For Dye Sensitized Solar Cells | A series of simple metal-free organic dyes MS1–MS3 have been designed and synthesized, and their optical, electrochemical, and photovoltaic properties were investigated. The molecular structures are based on a push–pull framework with a triphenylamine, naphthyldiphenylamine, or anthracenyl diphenylamine as the donor co... | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials",
"Materials Engineering"
] |
10.1038/nature13322 | Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis | Rheumatoid arthritis is a chronic autoinflammatory disease that affects 1-2% of the world's population and is characterized by widespread joint inflammation. Interleukin-1 is an important mediator of cartilage destruction in rheumatic diseases, but our understanding of the upstream mechanisms leading to production of i... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Physiology in Health, Disease and Ageing"
] |
10.1016/j.jas.2013.08.017 | Tortoise taphonomy and tortoise butchery patterns at Blombos Cave, South Africa | Tortoises are one of the most common faunal components at many Palaeolithic archaeological sites across the Old World. They provide protein, fat, and other 'animal' resources in a 'collectable' package. However, for most sites their interpretation as human food debris is based only on association, rather than demonstra... | [
"The Study of the Human Past",
"Environmental Biology, Ecology and Evolution"
] |
W2105711374 | Selective Exposure: New Methods and New Directions | This special issue of Communication Methods and Measures tackles difficult questions relating to the empirical study of politically motivated selective exposure. In this brief response, I reflect on the state of the research area and attempt to bring these articles into conversation with one another and with the larger... | [
"The Social World and Its Interactions",
"The Human Mind and Its Complexity"
] |
10.1016/j.jtrangeo.2013.06.007 | Mining bicycle sharing data for generating insights into sustainable transport systems | Bicycle sharing systems (bike-shares) are becoming increasingly popular in towns and cities around the world. They are viewed as a cheap, efficient, and healthy means of navigating dense urban environments. This paper is the first to take a global view of bike-sharing characteristics by analysing data from 38 systems l... | [
"Computer Science and Informatics",
"Human Mobility, Environment, and Space",
"Products and Processes Engineering"
] |
ES 2018070787 W | DOOR FOR RECEIVING AND DELIVERING ORDERS | The present invention relates to a door for receiving and delivering orders, characterized in that it comprises a hatch which can be arranged in an open position or in a closed position, and code entering means such that the hatch opens upon entering a predetermined code. | [
"Products and Processes Engineering",
"Systems and Communication Engineering"
] |
W4312078965 | Censimento preliminare della corrispondenza di Ulisse Aldrovandi | Il presente contributo intende offrire uno strumento per orientarsi all’interno della vasta e quasi totalmente inedita corrispondenza di Ulisse Aldrovandi (1522–1605). Il corpus di oltre duemila lettere in italiano e in latino copre l’intero arco temporale delle attività intellettuali e istituzionali di Aldrovandi (153... | [
"The Study of the Human Past",
"Texts and Concepts"
] |
10.1017/S0022050713000302 | Political Extremism In The 1920S And 1930S Do German Lessons Generalize | We examine the impact of the Great Depression on the share of votes for right-wing extremists in elections in the 1920s and 1930s. We confirm the existence of a link between political extremism and economic hard times as captured by growth or contraction of the economy. What mattered was not simply growth at the time o... | [
"Institutions, Governance and Legal Systems",
"Individuals, Markets and Organisations"
] |
10.1073/pnas.1205414109 | Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum | Epigenetic factors such as histone methylation control the developmental progression ofmalaria parasites during the complex life cycle in the human host. We investigated Plasmodium falciparum histone lysine methyltransferases as a potential target class for the development of novel antimalarials. We synthesized a compo... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Integrative Biology: from Genes and Genomes to Systems",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
220322 | Syrian imaginations of europe | Refugees’ attempts to flee to a certain country are usually preceded by imaginations about possible destination countries. These imaginations not only contribute to refugees’ decisions where to seek asylum but also have an effect on how refugees experience realities when they eventually arrive in the destination countr... | [
"The Social World and Its Interactions",
"Human Mobility, Environment, and Space",
"Institutions, Governance and Legal Systems"
] |
10.1039/C8CC03867H | The Impact Of Grafted Surface Defects On The On Surface Schiff Base Chemistry At The Solid Liquid Interface | We investigate the effect of covalently modified graphitic surfaces on the formation of single-layer covalent organic frameworks (sCOFs) at the solid–liquid interface. The impact of different densities of grafted aryl species was tested on the on-surface synthesis of three distinct imine-based 2D sCOFs. The grafted ary... | [
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
10.1371/journal.pone.0139010 | The effect of positive and negative feedback on risk-taking across different contexts | Preferences for risky choices have often been shown to be unstable and context-dependent. Though people generally avoid gambles with mixed outcomes, a phenomenon often attributed to loss aversion, contextual factors can impact this dramatically. For example, people typically prefer risky options after a financial loss,... | [
"The Human Mind and Its Complexity",
"Individuals, Markets and Organisations"
] |
US 9412571 W | MICROSTRUCTURE ARRAYS AND METHODS FOR THE FABRICATION THEREOF | A method is provided for fabricating smoothly-curved microstructures (12, 14, 16) such as microlenses on a substrate (18) and certain unique microstructures (12, 14, 16) and microstructure arrays (10) obtained through use of such techniques are also provided. The substrate (18) may be smoothly-curved and the bases of t... | [
"Condensed Matter Physics",
"Materials Engineering"
] |
10.1007/978-3-319-19231-4_9 | Quantum Light Storage In Solid State Atomic Ensembles | In this chapter, we will describe the storage and retrieval of quantum light (heralded single photons and entangled photons) in atomic ensembles in a solid state environment. We will consider ensembles of rare-earth ions embedded in dielectric crystals. We will describe the methods used to create quantum light spectral... | [
"Fundamental Constituents of Matter",
"Condensed Matter Physics",
"Physical and Analytical Chemical Sciences"
] |
335367 | Biologically individualized, model-based radiotherapy on the basis of multi-parametric molecular tumour profiling | High precision radiotherapy (RT) allows extremely flexible tumour treatments achieving highly conformal radiation doses while sparing surrounding organs at risk. Nevertheless, failure rates of up to 50% are reported for head and neck cancer (HNC) due to radiation resistance induced by pathophysiologic factors such as h... | [
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Physiology in Health, Disease and Ageing",
"Integrative Biology: from Genes and Genomes to Systems"
] |
10.1093/cercor/bhw155 | Learning a New Selection Rule in Visual and Frontal Cortex | How do you make a decision if you do not know the rules of the game? Models of sensory decision-making suggest that choices are slow if evidence is weak, but they may only apply if the subject knows the task rules. Here, we asked how the learning of a new rule influences neuronal activity in the visual (area V1) and fr... | [
"Neuroscience and Disorders of the Nervous System",
"The Human Mind and Its Complexity"
] |
US 0340381 W | SURGICAL BITING PUNCH | A surgical punch including an upper jaw and lower jaw that are coupled at their proximal ends. The jaws have cutting edges at their distal end configured to cut in a direction from the distal ends of the jaws towards the proximal ends of the jaws. The center of rotation of the cutting trajectory can be located above th... | [
"Products and Processes Engineering",
"Materials Engineering"
] |
W1489561631 | Model of human palm controlled by glove with micromachined accelerometers | The aim of the research presented in this paper was to test the possibility of inventing a fully autonomous device to detect the position of the fingers with the use of micromachined accelerometers. An implemented algorithm is based on the measurement of gravity acceleration. Designed microprocessor system analyses tha... | [
"Systems and Communication Engineering",
"Computer Science and Informatics"
] |
261162 | Single-Molecule BioAssays at Elevated Concentrations | In order to advance single-molecule fluorescence spectroscopy to the next level, handling and analysis of single molecules has to become broadly available. A further quantum leap is required to proceed to commercially successful applications such as drug screening and medical diagnostics.
In this project, I suggest a s... | [
"Physical and Analytical Chemical Sciences",
"Molecules of Life: Biological Mechanisms, Structures and Functions",
"Prevention, Diagnosis and Treatment of Human Diseases"
] |
Q4255555 | LIQUIDITY SUPPORT FOR MICRO-ENTERPRISES AFFECTED BY THE COVID EMERGENCY | SUPPORT FOR THE LIQUIDITY OF MICRO AND SMALL ENTERPRISES IN THE RETAIL, SUPPLY AND PERSONAL SERVICES SECTORS WHOSE ACTIVITY HAS BEEN SUSPENDED AS A RESULT OF THE PRIME MINISTERIAL DECREE OF 11 MARCH 2020 | [
"Individuals, Markets and Organisations",
"Institutions, Governance and Legal Systems"
] |
US 201715582196 A | Digital Content Rendering that Supports Alpha Is Shape (AIS) as part of Knockout Groups | Digital content rendering techniques are described that support Alpha Is Shape (AIS) as part of a knockout group. In order to support AIS rendering of an object within a knockout group, an alpha-separated color value is generated by removing an effect of an alpha value of an object of a knockout group on a pixel. A col... | [
"Computer Science and Informatics"
] |
10.1002/pan3.10154 | Ranger perceptions of, and engagement with, monitoring of elephant poaching | Ranger-based monitoring has enormous potential to inform conservation globally, with hundreds of thousands of rangers patrolling extensive areas and recording observations of illegal activities and biodiversity. Much quantitative research has demonstrated the pitfalls and potential of data collection by rangers, but li... | [
"Environmental Biology, Ecology and Evolution",
"The Social World and Its Interactions"
] |
10.1103/PhysRevD.94.096007 | Solving the standard model problems in softened gravity | The Higgs naturalness problem is solved if the growth of Einstein's gravitational interaction is softened at an energy ≤1011 GeV (softened gravity). We work here within an explicit realization where the Einstein Hilbert Lagrangian is extended to include terms quadratic in the curvature and a nonminimal coupling with th... | [
"Fundamental Constituents of Matter",
"Universe Sciences"
] |
10.1128/JVI.00038-09 | The Tight Junction Associated Protein Occludin Is Required For A Postbinding Step In Hepatitis C Virus Entry And Infection | The precise mechanisms regulating hepatitis C virus (HCV) entry into hepatic cells remain unknown. However, several cell surface proteins have been identified as entry factors for this virus. Of these molecules, claudin-1, a tight junction (TJ) component, is considered a coreceptor required for HCV entry. Recently, we ... | [
"Immunity, Infection and Immunotherapy",
"Molecules of Life: Biological Mechanisms, Structures and Functions"
] |
Q4248512 | APOYO A LA LIQUIDEZ PARA LAS MICROEMPRESAS AFECTADAS POR LA EMERGENCIA DE LA COVID | APOYO A LA LIQUIDEZ DE LAS MICROEMPRESAS Y LAS PEQUEÑAS EMPRESAS DE LOS SECTORES MINORISTA, DE SUMINISTRO Y DE SERVICIOS PERSONALES CUYA ACTIVIDAD HA SIDO SUSPENDIDA COMO CONSECUENCIA DEL DECRETO DEL PRIMER MINISTRO DE 11 DE MARZO DE 2020 | [
"Individuals, Markets and Organisations",
"Institutions, Governance and Legal Systems"
] |
616905 | Non-Invasive In-Vivo Histology in Health and Disease Using Magnetic Resonance Imaging (MRI) | Understanding of the normal and diseased brain crucially depends on reliable knowledge of its microstructure. Important functions are mediated by small cortical units (columns) and even small changes in the microstructure can cause debilitating diseases. So far, this microstructure can only be determined using invasive... | [
"Neuroscience and Disorders of the Nervous System",
"Prevention, Diagnosis and Treatment of Human Diseases",
"Physical and Analytical Chemical Sciences"
] |
714581 | Structure-performance relationships in porous carbons for energy storage | Supercapacitors are of great interest as energy storage systems because they exhibit very high rates of charge/discharge, long cycle lifes, and they are made of cheap and light materials. These attractive properties arise from the electrostatic nature of the charge storage which results from ion adsorption in the elect... | [
"Condensed Matter Physics",
"Materials Engineering",
"Physical and Analytical Chemical Sciences",
"Synthetic Chemistry and Materials"
] |
W1973382642 | Impact assessment of tritium in an ITER hot cell | Abstract Tritium concentration analysis in temporary storage, where large numbers of containers store tritiated metallic waste temporarily, is performed numerically using a time dependent tritium concentration model under an atmosphere detritiation system (ADS) and vent detritiation system (VDS). The tritium concentrat... | [
"Physical and Analytical Chemical Sciences",
"Products and Processes Engineering",
"Materials Engineering"
] |
Q4249551 | AIDE DE LIQUIDITÉ AUX MICROENTREPRISES TOUCHÉES PAR L’URGENCE LIÉE À LA COVID-19 | SOUTIEN À LA LIQUIDITÉ DES MICRO ET PETITES ENTREPRISES DANS LES SECTEURS DU COMMERCE DE DÉTAIL, DE LA FOURNITURE ET DES SERVICES PERSONNELS DONT L’ACTIVITÉ A ÉTÉ SUSPENDUE À LA SUITE DE L’ARRÊTÉ MINISTÉRIEL DU 11 MARS 2020 | [
"Individuals, Markets and Organisations"
] |
W2103086340 | Corotational instability, magnetic resonances and global inertial-acoustic oscillations in magnetized black hole accretion discs | Low-order, non-axisymmetric p-modes (also referred as inertial-acoustic modes) trapped in the inner-most region of hydrodynamic accretion discs around black holes, are plausible candidates for high-frequency quasi-periodic oscillations (QPOs) observed in a number of accreting black-hole systems. These modes are subject... | [
"Universe Sciences",
"Fundamental Constituents of Matter"
] |
10.1093/femsec/fiy145 | Microbial diversity along a gradient in peatlands treating mining-affected waters | Peatlands are used for the purification of mining-affected waters in Northern Finland. In Northern climate, microorganisms in treatment peatlands (TPs) are affected by long and cold winters, but studies about those microorganisms are scarce. Thus, the bacterial, archaeal and fungal communities along gradients of mine w... | [
"Environmental Biology, Ecology and Evolution",
"Earth System Science"
] |
10.1063/1.4791569 | Acks2 Atom Condensed Kohn Sham Dft Approximated To Second Order | A new polarizable force field (PFF), namely atom-condensed Kohn-Sham density functional theory approximated to second order (ACKS2), is proposed for the efficient computation of atomic charges and linear response properties of extended molecular systems. It is derived from Kohn-Sham density functional theory (KS-DFT), ... | [
"Physical and Analytical Chemical Sciences",
"Condensed Matter Physics"
] |
W2144887882 | Floodplain conflicts: regulation and negotiation | Abstract. In the continuing shift from engineered solutions towards more holistic methods of managing flood risk, spatial planning has become the primary focus of a conflict between land and water, water and people. In attempting to strike a balance between making space for water and making space for people, compromise... | [
"Earth System Science",
"Human Mobility, Environment, and Space",
"Institutions, Governance and Legal Systems"
] |
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