Datasets:
TabBioMed
/
vep_pathogenic_coding

Dataset card Data Studio Files
xet
 Community
row_idx
int64
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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
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T
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C
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T
C
A
G
T
T
A
C
C
T
0.056751
0.041096
0.04501
0.031311
0.052838
0.019569
0.015656
0.037182
0.050881
0.015656
0.015656
0.048924
0.02544
0.07045
0.033268
0.041096
0.02544
0.054795
0.017613
0.001957
0.001957
0.007828
0.009785
0.039139
0.054795
0.015656
0.017613
0.017613
0.035225
0.02544
0.029354
0.04501
0
34,893
A
A
T
T
C
A
C
A
T
G
A
G
A
G
A
G
A
A
A
T
C
C
T
A
T
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A
A
T
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T
C
C
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C
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T
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G
T
A
A
A
G
C
C
T
T
C
A
C
T
C
A
T
T
C
C
C
G
T
T
A
0.072407
0.021526
0.060665
0.041096
0.046967
0.013699
0.009785
0.033268
0.060665
0.023483
0.031311
0.029354
0.005871
0.076321
0.015656
0.033268
0.017613
0.023483
0.013699
0.007828
0.009785
0
0.015656
0.054795
0.080235
0.021526
0.023483
0.007828
0.041096
0.027397
0.029354
0.050881
0
34,894
T
T
T
T
G
T
G
A
T
T
T
T
G
A
A
A
G
G
A
A
C
A
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C
A
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A
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G
C
T
T
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C
C
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A
A
G
T
T
T
G
C
A
T
T
T
A
T
A
G
G
G
T
T
T
C
A
0.072407
0.029354
0.056751
0.037182
0.050881
0.017613
0.005871
0.033268
0.039139
0.023483
0.039139
0.04501
0.017613
0.064579
0.02544
0.033268
0.02544
0.02544
0.015656
0.005871
0.017613
0.001957
0.007828
0.043053
0.064579
0.015656
0.02544
0.015656
0.037182
0.029354
0.031311
0.046967
0
34,895
A
G
G
A
A
C
A
G
A
A
A
T
C
A
A
T
A
C
A
G
G
C
T
T
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C
C
C
A
A
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T
T
T
G
C
A
T
T
T
A
T
A
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G
G
T
T
T
C
T
C
T
C
C
A
G
T
A
T
G
A
G
T
T
G
0.07045
0.029354
0.056751
0.035225
0.052838
0.017613
0.005871
0.035225
0.035225
0.023483
0.039139
0.04501
0.017613
0.062622
0.027397
0.035225
0.027397
0.02544
0.015656
0.005871
0.017613
0.001957
0.007828
0.041096
0.062622
0.015656
0.029354
0.015656
0.037182
0.029354
0.031311
0.046967
0
34,896
A
A
G
C
T
T
G
A
G
C
G
A
T
G
A
G
A
T
A
A
T
G
C
T
T
T
C
C
C
A
C
A
C
T
G
C
T
T
G
C
A
T
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C
A
T
A
G
G
G
T
T
T
C
T
C
T
C
C
A
G
T
G
T
G
A
0.066536
0.033268
0.054795
0.027397
0.048924
0.019569
0.003914
0.037182
0.031311
0.02544
0.033268
0.039139
0.019569
0.07045
0.033268
0.043053
0.029354
0.033268
0.027397
0.005871
0.009785
0.003914
0.013699
0.029354
0.060665
0.019569
0.043053
0.013699
0.039139
0.013699
0.019569
0.050881
0
34,897
A
T
G
T
A
A
C
A
A
T
T
A
A
G
G
G
A
T
G
A
A
T
G
A
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C
C
A
T
G
A
C
T
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T
T
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C
T
C
C
T
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C
A
T
A
C
T
G
C
T
T
T
C
A
C
A
A
G
G
A
C
C
G
0.058708
0.033268
0.048924
0.039139
0.054795
0.021526
0.011742
0.039139
0.046967
0.015656
0.023483
0.043053
0.029354
0.060665
0.035225
0.041096
0.02544
0.043053
0.013699
0.001957
0.007828
0.005871
0.017613
0.033268
0.050881
0.021526
0.019569
0.013699
0.033268
0.031311
0.033268
0.04501
0
34,898
T
T
C
T
C
C
A
C
A
T
T
G
A
G
T
T
C
C
A
T
C
T
T
T
A
C
T
T
T
C
A
A
C
A
A
A
T
C
T
C
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T
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A
C
A
T
A
C
G
A
C
A
T
C
T
G
T
A
A
A
A
A
A
T
0.046967
0.035225
0.037182
0.054795
0.058708
0.021526
0.009785
0.035225
0.039139
0.015656
0.021526
0.050881
0.031311
0.066536
0.039139
0.037182
0.023483
0.039139
0.013699
0.001957
0.011742
0.003914
0.019569
0.031311
0.048924
0.021526
0.021526
0.009785
0.031311
0.031311
0.039139
0.050881
0
34,899
C
A
T
G
T
T
G
C
C
C
A
G
A
C
T
G
G
T
C
T
C
A
A
A
C
T
C
C
T
G
A
G
C
T
C
A
A
G
T
G
A
T
C
C
A
C
C
T
G
C
T
T
C
A
G
C
C
T
C
C
C
A
A
A
A
A
0.148728
0.027397
0.035225
0.033268
0.027397
0.029354
0.007828
0.04501
0.033268
0.02544
0.029354
0.027397
0.017613
0.019569
0.04501
0.046967
0.046967
0.054795
0.02544
0.001957
0.003914
0.001957
0.007828
0.043053
0.021526
0.017613
0.039139
0.027397
0.029354
0.017613
0.029354
0.033268
0
34,900
C
A
C
T
T
G
T
G
T
T
A
C
G
T
G
G
A
T
A
T
A
T
T
T
C
A
T
A
G
T
G
G
C
G
A
A
G
T
C
T
G
G
C
T
T
T
T
A
G
T
G
C
A
C
C
C
A
T
C
A
C
C
C
A
A
T
0.097847
0.043053
0.029354
0.041096
0.046967
0.027397
0.015656
0.035225
0.031311
0.017613
0.019569
0.046967
0.027397
0.04501
0.043053
0.037182
0.027397
0.046967
0.029354
0.005871
0.011742
0.005871
0.021526
0.02544
0.02544
0.017613
0.037182
0.013699
0.033268
0.027397
0.04501
0.021526
0
34,901
A
A
A
G
T
G
C
T
A
G
G
A
T
T
C
C
A
G
G
C
A
T
G
A
G
C
T
A
C
T
A
T
T
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C
C
G
G
C
C
C
A
A
C
A
T
T
C
T
C
A
T
T
T
T
C
T
G
A
A
A
G
C
A
A
G
0.103718
0.031311
0.041096
0.058708
0.021526
0.015656
0.003914
0.033268
0.041096
0.041096
0.031311
0.037182
0.029354
0.027397
0.035225
0.015656
0.043053
0.033268
0.019569
0.007828
0.009785
0.005871
0.02544
0.037182
0.039139
0.011742
0.033268
0.02544
0.031311
0.017613
0.056751
0.035225
0
34,902
A
T
T
G
C
T
T
T
C
A
G
A
A
A
A
T
G
A
G
A
A
T
G
T
T
G
G
G
C
C
G
G
T
A
A
T
A
G
T
A
G
C
T
C
A
T
G
C
C
T
G
G
A
A
T
C
C
T
A
G
C
A
C
T
T
G
0.103718
0.029354
0.041096
0.058708
0.021526
0.015656
0.003914
0.033268
0.041096
0.041096
0.031311
0.037182
0.029354
0.027397
0.035225
0.017613
0.043053
0.033268
0.019569
0.007828
0.009785
0.005871
0.02544
0.037182
0.039139
0.011742
0.033268
0.02544
0.031311
0.017613
0.056751
0.035225
0
34,903
G
G
T
G
A
A
G
T
G
A
T
C
T
T
T
G
A
A
G
C
C
T
C
T
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A
G
C
C
G
C
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C
C
A
G
C
G
C
G
T
T
G
C
T
C
A
G
A
A
G
A
A
C
C
T
G
C
G
G
A
A
G
A
G
A
0.031311
0.023483
0.037182
0.005871
0.017613
0.02544
0.023483
0.015656
0.043053
0.043053
0.056751
0.011742
0.017613
0.011742
0.027397
0.02544
0.046967
0.035225
0.09002
0.039139
0.007828
0.050881
0.019569
0.054795
0.029354
0.02544
0.027397
0.062622
0.043053
0.009785
0.009785
0.031311
0
34,904
T
G
G
C
C
G
C
C
A
G
G
C
C
C
A
C
C
A
G
C
G
C
C
T
C
C
A
G
C
T
G
G
T
T
G
C
A
C
A
C
C
T
G
G
A
G
G
C
A
G
A
G
G
G
G
T
A
T
G
T
T
G
G
G
G
C
0.064579
0.023483
0.023483
0.003914
0.017613
0.037182
0.017613
0.029354
0.02544
0.035225
0.052838
0.003914
0.007828
0.019569
0.023483
0.033268
0.050881
0.048924
0.082192
0.041096
0.023483
0.027397
0.017613
0.050881
0.021526
0.027397
0.039139
0.07045
0.035225
0.015656
0.005871
0.023483
0
34,905
G
G
G
T
A
G
G
C
G
C
A
C
T
G
A
C
C
T
G
C
G
C
A
T
T
T
A
C
C
A
G
C
C
G
G
A
T
G
A
G
C
T
T
G
T
C
A
A
G
G
T
T
C
T
T
G
A
A
C
C
A
C
A
T
G
T
0.023483
0.02544
0.033268
0.023483
0.064579
0.041096
0.001957
0.019569
0.027397
0.037182
0.035225
0.033268
0.019569
0.058708
0.043053
0.048924
0.04501
0.050881
0.046967
0.019569
0.001957
0.019569
0.017613
0.023483
0.021526
0.023483
0.048924
0.039139
0.027397
0.029354
0.017613
0.031311
0
34,906
T
G
T
G
C
T
G
G
G
A
T
G
T
G
C
T
G
T
G
T
G
T
C
G
A
T
C
A
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C
C
G
C
T
G
G
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G
G
A
G
G
A
C
C
C
T
C
G
C
A
G
C
C
C
C
G
A
G
T
A
C
A
A
C
G
0.033268
0.023483
0.031311
0.029354
0.046967
0.043053
0.005871
0.023483
0.027397
0.031311
0.052838
0.019569
0.023483
0.02544
0.035225
0.04501
0.064579
0.060665
0.046967
0.015656
0.019569
0.009785
0.007828
0.031311
0.031311
0.029354
0.037182
0.041096
0.04501
0.021526
0.017613
0.023483
0
34,907
A
C
T
C
C
T
C
A
C
C
T
C
A
T
G
G
G
T
A
C
T
A
T
T
T
C
G
C
T
T
A
G
T
G
C
C
T
A
A
G
G
T
C
T
T
G
A
T
C
A
G
A
A
C
C
T
G
G
T
T
G
G
A
C
T
C
0.017613
0.019569
0.035225
0.017613
0.027397
0.04501
0.013699
0.033268
0.035225
0.023483
0.058708
0.011742
0.029354
0.035225
0.02544
0.04501
0.056751
0.050881
0.052838
0.015656
0.013699
0.011742
0.017613
0.041096
0.02544
0.039139
0.037182
0.04501
0.035225
0.015656
0.021526
0.046967
0
34,908
A
T
C
A
C
C
T
T
G
C
T
C
C
C
T
T
T
C
C
A
G
G
G
T
G
G
G
T
C
A
C
T
C
T
G
T
C
T
G
T
C
G
G
G
C
T
C
C
C
G
A
G
A
T
C
G
C
A
A
C
G
T
C
A
A
G
0.017613
0.021526
0.031311
0.009785
0.023483
0.050881
0.015656
0.033268
0.033268
0.029354
0.058708
0.009785
0.021526
0.017613
0.029354
0.04501
0.068493
0.056751
0.060665
0.021526
0.015656
0.017613
0.015656
0.039139
0.021526
0.039139
0.039139
0.054795
0.031311
0.017613
0.011742
0.041096
0
34,909
T
C
A
G
A
A
G
G
C
C
C
G
G
C
T
C
A
C
T
T
A
C
G
G
C
C
G
A
A
A
C
C
C
T
G
G
A
C
G
C
G
G
C
C
C
G
A
G
G
C
T
C
C
G
A
A
G
C
G
C
T
C
G
G
G
T
0.005871
0.005871
0.015656
0.005871
0.013699
0.035225
0.039139
0.009785
0.02544
0.041096
0.048924
0.001957
0.013699
0.009785
0.007828
0.033268
0.04501
0.039139
0.080235
0.072407
0.033268
0.105675
0.019569
0.04501
0.017613
0.043053
0.02544
0.082192
0.043053
0.015656
0.001957
0.017613
0
34,910
G
A
C
C
G
G
G
A
G
C
G
G
C
A
G
G
A
G
G
A
G
C
T
G
C
A
G
C
G
C
C
A
C
C
T
G
G
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G
G
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T
G
C
C
A
A
C
C
G
C
G
C
G
C
G
C
C
A
C
G
G
G
T
T
G
0.005871
0.013699
0.015656
0
0.013699
0.046967
0.007828
0.013699
0.027397
0.066536
0.07045
0.001957
0.005871
0.007828
0.011742
0.035225
0.084149
0.050881
0.086106
0.043053
0.015656
0.050881
0.013699
0.064579
0.015656
0.027397
0.056751
0.068493
0.052838
0.005871
0.001957
0.017613
0
34,911
T
C
C
C
G
T
T
G
C
C
G
G
C
A
G
G
G
C
C
G
T
A
A
C
T
G
G
A
T
C
A
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C
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C
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C
G
G
G
T
C
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A
T
G
A
A
A
A
C
C
G
G
G
C
C
C
G
G
C
G
C
G
0.013699
0.015656
0.041096
0.011742
0.009785
0.023483
0.013699
0.033268
0.04501
0.039139
0.050881
0.013699
0.019569
0.013699
0.027397
0.027397
0.041096
0.033268
0.086106
0.046967
0.019569
0.035225
0.019569
0.066536
0.031311
0.02544
0.037182
0.058708
0.048924
0.011742
0.009785
0.029354
0
34,912
G
A
A
A
T
G
G
C
A
G
T
T
C
G
T
G
G
A
G
A
A
A
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C
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G
A
C
T
T
G
G
A
T
A
C
T
G
A
T
T
A
T
G
G
C
T
C
A
G
G
C
T
A
C
C
C
C
A
A
T
G
C
0.084149
0.023483
0.029354
0.029354
0.021526
0.041096
0.011742
0.02544
0.02544
0.033268
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0.019569
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0.033268
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0.050881
0.064579
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0.017613
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0.027397
0.017613
0.041096
0.056751
0.033268
0.017613
0.019569
0.031311
0
34,913
G
G
C
T
G
C
G
G
G
A
A
C
G
C
C
G
G
G
A
G
G
G
A
G
C
T
T
C
C
C
G
G
C
C
C
C
G
T
C
G
T
C
C
T
G
G
T
C
T
G
G
G
A
C
G
A
G
G
T
A
C
C
G
C
G
G
0.019569
0.013699
0.021526
0.009785
0.015656
0.031311
0.031311
0.017613
0.033268
0.039139
0.060665
0.003914
0.009785
0.009785
0.009785
0.031311
0.048924
0.052838
0.097847
0.050881
0.019569
0.043053
0.017613
0.062622
0.023483
0.041096
0.019569
0.058708
0.072407
0.009785
0.011742
0.011742
0
34,914
C
C
C
A
G
A
C
C
T
G
C
G
C
T
C
T
G
G
C
G
C
C
C
A
G
C
G
A
G
G
C
C
T
C
C
G
G
G
G
C
G
C
A
A
T
A
T
C
C
G
C
C
G
C
C
G
C
C
C
G
A
G
A
C
T
C
0.003914
0.009785
0.015656
0.001957
0.005871
0.039139
0.013699
0.013699
0.019569
0.046967
0.050881
0.007828
0.011742
0.009785
0.011742
0.031311
0.046967
0.056751
0.103718
0.088063
0.029354
0.076321
0.001957
0.062622
0.015656
0.02544
0.02544
0.101761
0.054795
0.005871
0
0.011742
0
34,915
C
T
C
G
G
G
C
A
G
C
T
C
T
C
G
G
A
T
T
C
T
G
G
G
A
C
A
G
A
G
T
C
C
A
C
C
T
G
C
G
G
C
A
G
A
C
A
G
A
C
A
G
C
T
G
A
A
C
A
G
G
G
G
C
A
G
0.011742
0.013699
0.027397
0.005871
0.031311
0.037182
0.017613
0.031311
0.037182
0.037182
0.048924
0
0.011742
0.005871
0.009785
0.050881
0.068493
0.031311
0.082192
0.052838
0.029354
0.039139
0.011742
0.046967
0.029354
0.048924
0.048924
0.050881
0.046967
0.003914
0.007828
0.023483
0
34,916
G
A
G
A
A
T
T
C
C
A
T
C
T
T
C
T
T
T
T
T
A
A
G
G
A
A
C
A
C
A
T
C
T
G
A
A
C
G
A
C
T
T
C
A
G
A
A
G
G
G
A
A
A
T
T
T
T
G
A
T
A
T
T
T
A
C
0.039139
0.015656
0.037182
0.027397
0.027397
0.017613
0.015656
0.029354
0.056751
0.04501
0.043053
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0.017613
0.039139
0.052838
0.041096
0.046967
0.013699
0.003914
0.017613
0.011742
0.072407
0.039139
0.021526
0.029354
0.02544
0.054795
0.013699
0.023483
0.046967
0
34,917
T
C
G
A
G
T
C
T
C
A
C
A
G
A
G
A
C
A
T
T
A
T
T
T
G
G
C
G
C
G
G
C
C
A
G
C
T
C
T
G
C
G
G
C
A
G
G
A
G
C
G
C
T
C
A
G
G
C
C
T
C
A
G
T
C
A
0.080235
0.021526
0.04501
0.015656
0.027397
0.013699
0.005871
0.009785
0.060665
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0.088063
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0.017613
0.041096
0.076321
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0.013699
0.035225
0
34,918
A
C
G
C
A
G
C
A
G
C
A
G
C
C
T
G
A
G
C
G
A
C
G
G
C
G
G
G
G
A
C
G
C
T
G
G
A
C
T
G
G
T
C
C
C
G
A
G
C
A
A
G
A
A
A
G
C
C
C
G
T
C
T
G
G
T
0.015656
0.011742
0.029354
0.001957
0.011742
0.019569
0.033268
0.009785
0.023483
0.048924
0.054795
0
0.005871
0.007828
0.021526
0.021526
0.046967
0.021526
0.068493
0.088063
0.04501
0.080235
0
0.062622
0.021526
0.041096
0.050881
0.093933
0.048924
0
0
0.013699
0
34,919
G
G
T
G
G
C
C
A
T
G
G
C
A
G
G
G
A
T
G
G
C
C
A
G
C
A
T
G
G
G
G
C
C
G
G
G
G
T
C
G
G
T
G
C
T
G
T
T
T
C
C
C
A
T
C
T
T
G
G
C
T
G
G
G
C
T
0.009785
0.035225
0.023483
0.013699
0.029354
0.056751
0.013699
0.007828
0.031311
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0.007828
0.015656
0.021526
0.043053
0.037182
0.054795
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0.013699
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0.02544
0.033268
0.021526
0.084149
0.033268
0.003914
0.003914
0.019569
0
34,920
G
C
A
T
G
G
T
G
G
A
C
C
A
A
G
G
C
C
C
G
G
G
T
C
C
A
G
C
C
C
T
C
C
C
C
C
C
A
C
C
A
C
A
T
C
C
T
A
G
C
T
T
T
G
A
G
C
A
G
G
C
C
A
C
T
A
0.017613
0.015656
0.02544
0.015656
0.031311
0.027397
0.009785
0.021526
0.039139
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0.027397
0.02544
0.037182
0.056751
0.04501
0.013699
0.009785
0.033268
0
34,921
G
C
T
G
C
G
T
G
C
C
G
G
A
C
C
A
T
G
G
C
G
C
A
G
G
G
G
C
A
G
C
G
C
A
A
G
T
T
T
C
A
G
G
C
G
C
A
C
A
A
A
C
C
C
G
C
A
A
A
G
A
G
T
A
A
T
0.043053
0.031311
0.043053
0.007828
0.035225
0.019569
0.031311
0.023483
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0.043053
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0.029354
0.019569
0.039139
0.050881
0.037182
0.017613
0.021526
0.023483
0
34,922
T
G
A
G
C
T
T
T
T
G
C
T
G
C
T
G
C
A
C
G
A
C
G
C
G
C
G
C
C
T
T
C
T
T
G
G
G
A
G
C
G
A
T
A
A
C
A
C
G
A
C
C
T
G
G
G
G
A
A
A
G
A
T
G
T
C
0.019569
0.011742
0.039139
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0.011742
0.027397
0.021526
0.013699
0.031311
0.048924
0.054795
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0.011742
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0.035225
0.035225
0.099804
0.058708
0.027397
0.064579
0.011742
0.062622
0.027397
0.019569
0.035225
0.062622
0.056751
0.009785
0.009785
0.015656
0
34,923
T
G
T
G
T
G
T
G
A
G
G
A
G
G
G
C
A
C
C
C
T
C
T
C
C
C
C
C
G
C
A
C
C
A
T
G
C
C
C
G
G
G
G
T
C
T
C
C
G
C
A
G
C
C
T
G
T
C
C
C
C
T
C
C
T
A
0.009785
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0.005871
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0.015656
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0.084149
0.019569
0.019569
0.035225
0.068493
0.062622
0.001957
0.009785
0.019569
0
34,924
C
C
C
T
C
C
C
A
C
C
T
G
C
C
T
C
A
C
C
T
C
T
A
G
C
A
G
G
C
G
C
A
C
G
A
A
C
T
C
C
T
C
C
A
G
A
G
T
C
T
T
C
A
C
T
G
C
C
A
C
A
C
C
C
A
T
0.04501
0.019569
0.013699
0.013699
0.033268
0.027397
0.013699
0.017613
0.037182
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0
0.013699
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0.019569
0.041096
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0.064579
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0.005871
0.019569
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0.054795
0.023483
0.02544
0.041096
0.084149
0.04501
0.003914
0.005871
0.029354
0
34,925
C
T
G
C
C
A
G
C
T
C
T
G
A
G
G
T
G
G
T
G
T
C
T
G
G
A
A
T
G
C
C
C
T
G
C
T
G
A
G
C
C
C
C
G
G
G
C
T
C
C
T
G
G
A
G
A
G
G
G
T
C
G
T
C
T
C
0.003914
0.015656
0.017613
0.009785
0.035225
0.043053
0.007828
0.017613
0.04501
0.050881
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0.011742
0.023483
0.011742
0.043053
0.091977
0.052838
0.052838
0.021526
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0.007828
0.068493
0.027397
0.039139
0.054795
0.050881
0.048924
0.005871
0.003914
0.027397
0
34,926
G
G
G
G
A
C
A
C
C
G
T
C
T
C
C
C
T
C
C
T
C
C
T
G
G
G
G
C
C
C
T
C
C
A
G
G
C
A
G
G
C
C
A
G
C
C
C
C
T
G
C
T
G
T
C
C
T
T
T
G
G
G
C
C
C
T
0.005871
0.011742
0.023483
0.005871
0.031311
0.043053
0.005871
0.007828
0.037182
0.043053
0.086106
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0.017613
0.017613
0.019569
0.023483
0.091977
0.056751
0.113503
0.021526
0.005871
0.005871
0.007828
0.052838
0.021526
0.043053
0.031311
0.064579
0.058708
0.009785
0
0.033268
0
34,927
G
G
T
C
C
G
C
A
G
C
T
T
C
T
T
C
C
T
C
T
T
A
G
T
C
A
T
T
T
T
A
T
C
T
T
C
C
C
C
T
T
G
A
G
A
A
A
T
C
T
G
A
A
A
A
C
A
A
G
C
A
A
A
A
T
A
0.039139
0.023483
0.048924
0.027397
0.035225
0.033268
0.005871
0.021526
0.048924
0.037182
0.052838
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0.033268
0.062622
0.052838
0.037182
0.011742
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0.005871
0.007828
0.043053
0.033268
0.027397
0.029354
0.04501
0.039139
0.011742
0.027397
0.043053
0
34,928
T
C
G
G
G
A
G
C
C
A
C
T
G
A
C
A
G
C
C
C
A
G
C
A
G
T
T
G
G
A
G
A
C
G
A
C
G
A
C
A
G
A
G
A
G
G
T
G
G
C
T
G
G
T
C
A
T
T
G
A
C
C
C
T
G
T
0.04501
0.02544
0.021526
0.011742
0.029354
0.04501
0.003914
0.029354
0.037182
0.031311
0.060665
0.003914
0.011742
0.011742
0.027397
0.037182
0.084149
0.07045
0.091977
0.013699
0.011742
0.005871
0.007828
0.04501
0.027397
0.037182
0.035225
0.052838
0.048924
0.007828
0.003914
0.023483
0
34,929
G
T
A
G
A
A
C
T
G
C
A
G
C
T
G
C
C
G
C
T
C
C
A
G
C
T
G
G
G
C
T
G
C
G
T
A
T
T
C
T
G
A
G
A
A
T
G
G
A
T
G
G
C
G
G
G
G
G
A
A
T
G
G
A
G
T
0.001957
0.007828
0.009785
0.009785
0.009785
0.033268
0.009785
0.013699
0.019569
0.048924
0.064579
0.005871
0.029354
0.029354
0.009785
0.037182
0.064579
0.066536
0.146771
0.033268
0.015656
0.023483
0.015656
0.056751
0.011742
0.009785
0.052838
0.072407
0.060665
0.011742
0.005871
0.011742
0
34,930
C
T
T
C
C
G
C
C
G
G
G
C
C
A
A
A
G
A
G
G
C
C
A
A
G
G
G
C
G
G
G
G
T
C
C
C
T
G
A
G
G
A
A
G
C
C
C
G
G
C
C
T
G
C
C
C
T
G
T
G
C
C
C
A
G
C
0.009785
0.007828
0.023483
0.003914
0.031311
0.021526
0.007828
0.013699
0.037182
0.050881
0.07045
0.005871
0.009785
0.019569
0.017613
0.033268
0.076321
0.052838
0.105675
0.043053
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0.021526
0.011742
0.060665
0.015656
0.023483
0.041096
0.101761
0.04501
0.007828
0.001957
0.021526
0
34,931
C
A
G
C
C
A
G
G
A
C
A
T
C
T
C
G
G
C
T
G
C
C
C
C
G
A
A
G
A
A
C
C
C
C
A
G
G
G
G
T
T
C
C
T
T
G
C
C
A
G
C
T
G
G
G
T
C
G
C
C
C
C
C
T
G
A
0.021526
0.015656
0.027397
0.009785
0.037182
0.02544
0.001957
0.039139
0.033268
0.056751
0.043053
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0.027397
0.035225
0.023483
0.041096
0.09002
0.060665
0.056751
0.011742
0.015656
0.005871
0.023483
0.031311
0.02544
0.037182
0.048924
0.064579
0.02544
0.009785
0.003914
0.04501
0
34,932
C
C
A
G
C
T
G
G
A
A
C
C
G
G
A
G
C
T
G
A
A
G
A
C
C
A
T
A
C
C
C
C
T
G
A
C
C
C
C
T
G
T
T
G
A
G
A
T
C
C
A
A
G
A
T
T
T
G
G
A
G
C
T
A
G
C
0.050881
0.019569
0.033268
0.019569
0.035225
0.029354
0.009785
0.023483
0.041096
0.039139
0.046967
0.013699
0.033268
0.019569
0.041096
0.04501
0.050881
0.066536
0.062622
0.013699
0.007828
0.011742
0.011742
0.054795
0.027397
0.021526
0.019569
0.046967
0.050881
0.013699
0.003914
0.035225
0
34,933
C
A
T
G
G
G
A
A
T
A
G
G
A
A
G
T
G
A
G
G
A
A
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C
C
A
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A
C
A
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A
G
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G
A
T
G
A
A
G
C
G
G
A
G
A
T
G
T
C
A
C
C
A
G
T
G
G
G
0.029354
0.011742
0.048924
0.009785
0.007828
0.027397
0.001957
0.019569
0.076321
0.031311
0.091977
0.003914
0.015656
0.021526
0.013699
0.027397
0.039139
0.048924
0.066536
0.011742
0.007828
0.009785
0.009785
0.121331
0.056751
0.011742
0.019569
0.033268
0.091977
0.005871
0
0.027397
0
34,934
C
T
C
C
C
C
C
A
T
G
G
C
C
T
C
T
G
C
A
T
C
A
C
T
G
C
C
A
C
C
C
A
C
C
C
C
C
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C
C
C
A
G
A
C
C
A
C
C
T
C
C
A
C
G
A
T
G
C
C
C
C
T
G
T
T
0.003914
0.001957
0.029354
0.003914
0.015656
0.039139
0.007828
0.019569
0.033268
0.04501
0.09002
0.003914
0.019569
0.019569
0.005871
0.058708
0.060665
0.068493
0.09589
0.015656
0.013699
0.005871
0.019569
0.078278
0.023483
0.017613
0.035225
0.068493
0.066536
0.001957
0.005871
0.02544
0
34,935
C
G
G
C
A
G
G
T
T
G
A
G
C
A
C
C
G
G
C
C
G
C
A
C
G
C
G
C
A
G
C
T
C
G
A
C
G
A
G
T
T
C
A
C
G
G
C
C
T
G
C
G
C
G
G
C
C
C
G
G
G
C
T
C
A
G
0.007828
0.011742
0.013699
0.001957
0.001957
0.021526
0.019569
0.003914
0.009785
0.054795
0.048924
0
0.009785
0.011742
0.005871
0.011742
0.043053
0.02544
0.099804
0.103718
0.037182
0.144814
0.001957
0.058708
0.019569
0.023483
0.035225
0.105675
0.052838
0
0.001957
0.011742
0
34,936
C
C
C
C
G
C
A
G
C
G
A
G
C
A
G
G
G
G
C
G
A
C
G
G
A
A
A
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T
T
G
G
T
G
G
T
G
A
T
C
T
G
G
C
C
C
C
C
C
C
G
C
A
G
A
A
A
G
G
T
C
T
C
G
G
C
0.019569
0.021526
0.02544
0.007828
0.011742
0.050881
0.013699
0.017613
0.029354
0.033268
0.066536
0
0.011742
0.015656
0.011742
0.04501
0.058708
0.056751
0.101761
0.041096
0.013699
0.033268
0.003914
0.058708
0.037182
0.02544
0.035225
0.054795
0.062622
0.001957
0.005871
0.027397
0
34,937
G
G
C
A
G
G
G
G
C
C
C
G
G
G
C
T
G
G
G
G
T
C
C
A
G
G
C
T
C
A
C
A
T
G
G
C
A
C
G
G
G
G
C
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C
A
G
A
G
A
A
C
A
C
G
T
C
G
C
T
G
T
G
G
A
C
0.013699
0.007828
0.033268
0.003914
0.027397
0.033268
0.013699
0.021526
0.041096
0.050881
0.052838
0.011742
0.017613
0.02544
0.013699
0.052838
0.064579
0.058708
0.09002
0.029354
0.009785
0.013699
0.005871
0.062622
0.023483
0.02544
0.039139
0.060665
0.046967
0.009785
0.007828
0.031311
0
34,938
G
C
C
T
G
T
A
A
T
C
C
C
A
G
C
A
C
T
T
C
G
G
G
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G
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C
C
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C
G
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A
T
C
A
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T
T
G
A
G
G
C
C
A
G
G
A
G
T
T
C
A
G
G
A
C
T
0.048924
0.011742
0.013699
0.013699
0.015656
0.031311
0.009785
0.033268
0.023483
0.037182
0.074364
0.003914
0.015656
0.009785
0.011742
0.043053
0.068493
0.058708
0.072407
0.027397
0.017613
0.019569
0.009785
0.076321
0.017613
0.021526
0.033268
0.064579
0.064579
0.013699
0.011742
0.02544
0
34,939
C
T
C
C
C
C
G
G
T
G
A
A
C
T
C
C
T
C
G
T
C
G
A
A
G
T
T
G
C
T
G
A
C
G
T
C
G
G
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G
C
G
G
C
C
G
G
A
C
A
G
C
G
T
G
G
G
C
A
C
A
A
A
G
G
T
0.017613
0.007828
0.029354
0.003914
0.019569
0.019569
0.019569
0.02544
0.019569
0.043053
0.064579
0.001957
0.011742
0.005871
0.017613
0.043053
0.060665
0.041096
0.121331
0.048924
0.021526
0.035225
0.005871
0.056751
0.017613
0.031311
0.046967
0.076321
0.058708
0.001957
0.005871
0.019569
0
34,940
A
C
A
C
T
G
A
G
C
C
C
G
C
C
C
C
G
C
G
A
C
G
C
G
C
G
G
C
C
C
C
T
C
A
C
A
G
C
C
G
C
G
G
A
G
C
A
G
G
C
A
G
C
C
T
T
C
C
T
G
G
A
C
T
T
T
0.019569
0.009785
0.027397
0.003914
0.019569
0.023483
0.02544
0.02544
0.015656
0.041096
0.058708
0.001957
0.011742
0.009785
0.019569
0.046967
0.056751
0.04501
0.117417
0.046967
0.02544
0.035225
0.005871
0.050881
0.015656
0.037182
0.048924
0.074364
0.052838
0.001957
0.005871
0.019569
0
34,941
A
G
G
C
G
G
A
C
G
A
G
G
C
G
G
A
G
G
C
C
G
A
G
C
G
G
G
G
T
C
C
G
T
G
C
G
C
C
C
C
C
C
A
G
C
G
A
C
G
C
C
G
G
C
T
G
T
C
G
G
G
G
C
C
T
C
0.003914
0.001957
0.017613
0.001957
0.013699
0.027397
0.035225
0.003914
0.013699
0.066536
0.04501
0.003914
0.009785
0.015656
0.011742
0.041096
0.050881
0.054795
0.068493
0.07045
0.046967
0.09002
0.003914
0.058708
0.009785
0.029354
0.041096
0.107632
0.035225
0.007828
0
0.011742
0
34,942
T
G
G
C
C
G
C
C
C
T
G
G
C
T
C
T
G
G
C
C
C
A
C
A
A
C
T
G
G
G
C
A
C
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G
G
C
C
G
A
G
G
G
A
C
C
C
T
G
C
G
G
C
T
C
C
G
A
T
C
C
C
G
G
G
G
0.035225
0.017613
0.027397
0.005871
0.017613
0.033268
0.007828
0.031311
0.033268
0.039139
0.056751
0.003914
0.029354
0.015656
0.021526
0.050881
0.072407
0.068493
0.074364
0.031311
0.007828
0.011742
0.005871
0.054795
0.02544
0.015656
0.04501
0.066536
0.054795
0.005871
0.003914
0.029354
0
34,943
T
C
T
T
G
A
A
A
T
G
A
C
T
T
T
C
T
C
A
T
C
T
C
T
T
C
T
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G
G
C
C
T
G
G
A
C
C
T
C
G
C
C
G
C
T
G
T
C
A
C
C
T
G
T
C
C
A
C
C
T
C
C
T
C
C
0.039139
0.021526
0.043053
0.017613
0.021526
0.039139
0
0.033268
0.04501
0.041096
0.068493
0.009785
0.015656
0.015656
0.033268
0.035225
0.07045
0.050881
0.050881
0.005871
0.003914
0.005871
0.011742
0.064579
0.037182
0.029354
0.035225
0.035225
0.050881
0.009785
0.011742
0.046967
0
34,944
A
G
A
G
C
T
G
C
A
G
A
T
G
C
A
G
T
G
A
G
G
T
G
C
T
G
G
T
G
T
T
C
C
G
G
A
T
G
G
C
T
T
T
A
C
A
C
A
G
G
A
G
A
A
A
A
G
T
G
A
G
G
G
C
C
T
0.033268
0.011742
0.027397
0.023483
0.033268
0.027397
0.013699
0.031311
0.04501
0.043053
0.054795
0.009785
0.031311
0.029354
0.015656
0.043053
0.062622
0.041096
0.04501
0.013699
0.011742
0.007828
0.029354
0.054795
0.029354
0.02544
0.04501
0.029354
0.052838
0.02544
0.021526
0.031311
0
34,945
A
T
T
C
C
A
T
C
T
T
T
C
T
G
T
T
T
C
C
T
C
A
G
G
T
C
C
C
A
G
T
G
C
C
A
T
T
G
C
C
T
T
T
A
T
C
T
C
A
T
A
T
T
C
T
T
C
T
C
T
T
G
G
A
A
T
0.09589
0.023483
0.048924
0.019569
0.029354
0.02544
0.015656
0.029354
0.058708
0.029354
0.039139
0.019569
0.035225
0.023483
0.039139
0.043053
0.04501
0.046967
0.021526
0.007828
0.005871
0.009785
0.011742
0.050881
0.037182
0.021526
0.029354
0.033268
0.035225
0.011742
0.011742
0.04501
0
34,946
G
G
A
T
C
A
G
C
C
T
C
C
A
C
T
C
A
C
C
T
C
T
T
T
C
C
T
G
C
C
C
T
C
G
G
T
T
G
T
C
T
T
T
G
A
G
G
A
G
G
T
G
G
T
G
T
C
T
G
C
A
A
A
A
G
G
0.099804
0.021526
0.023483
0.072407
0.039139
0.027397
0
0.027397
0.029354
0.013699
0.033268
0.129159
0.019569
0.033268
0.037182
0.023483
0.033268
0.029354
0.033268
0.001957
0.001957
0
0.015656
0.031311
0.015656
0.017613
0.023483
0.017613
0.019569
0.031311
0.064579
0.033268
0
34,947
A
G
A
A
C
A
G
G
C
A
C
T
T
T
T
C
T
C
C
A
G
C
C
C
A
C
T
G
G
A
G
A
C
C
A
T
G
A
G
T
G
G
C
T
C
C
A
G
G
T
C
C
A
G
C
C
C
T
T
G
G
T
C
C
A
A
0.088063
0.033268
0.037182
0.048924
0.058708
0.009785
0.001957
0.031311
0.056751
0.041096
0.02544
0.035225
0.021526
0.029354
0.046967
0.035225
0.046967
0.043053
0.017613
0
0.001957
0
0.019569
0.050881
0.037182
0.019569
0.021526
0.023483
0.035225
0.013699
0.033268
0.035225
0
34,948
C
A
G
A
T
T
C
A
G
A
G
G
G
T
G
G
T
G
A
T
A
C
C
A
G
T
G
C
C
T
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C
T
C
T
G
G
G
C
C
A
C
C
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C
A
A
C
C
C
A
T
G
G
G
T
G
G
C
C
A
G
G
G
A
A
0.031311
0.015656
0.033268
0.031311
0.037182
0.029354
0.011742
0.031311
0.054795
0.019569
0.052838
0.02544
0.031311
0.021526
0.02544
0.060665
0.062622
0.052838
0.043053
0.005871
0
0.005871
0.011742
0.052838
0.027397
0.021526
0.039139
0.04501
0.037182
0.013699
0.027397
0.041096
0
34,949
G
A
T
A
C
A
C
A
C
A
G
G
G
G
A
G
A
A
A
C
T
G
T
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G
A
G
T
G
C
G
C
G
A
C
T
T
G
C
G
G
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C
A
G
G
T
C
T
T
G
A
G
T
C
G
T
C
T
T
T
C
A
A
T
0.017613
0.021526
0.046967
0.017613
0.054795
0.017613
0.011742
0.037182
0.04501
0.02544
0.043053
0.017613
0.021526
0.048924
0.027397
0.062622
0.046967
0.033268
0.035225
0.011742
0.013699
0.017613
0.005871
0.052838
0.052838
0.023483
0.041096
0.037182
0.033268
0.013699
0.005871
0.058708
0
34,950
C
C
A
T
C
T
T
A
C
C
T
T
G
T
G
T
T
C
C
G
G
A
G
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G
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G
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C
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C
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G
A
G
G
A
G
A
G
T
C
T
G
T
T
T
T
T
C
A
A
G
0.068493
0.033268
0.029354
0.023483
0.050881
0.037182
0.001957
0.021526
0.066536
0.02544
0.041096
0.013699
0.027397
0.029354
0.033268
0.041096
0.060665
0.04501
0.037182
0.011742
0.007828
0.005871
0.009785
0.054795
0.043053
0.027397
0.027397
0.027397
0.035225
0.009785
0.009785
0.043053
0
34,951
A
A
G
A
G
G
T
A
C
A
G
G
G
C
C
T
C
C
A
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C
A
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C
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G
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C
C
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T
A
G
A
G
A
T
A
G
T
G
C
A
A
G
G
T
A
C
C
G
0.021526
0.023483
0.029354
0.037182
0.031311
0.035225
0.007828
0.023483
0.046967
0.031311
0.04501
0.043053
0.027397
0.043053
0.033268
0.037182
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0.015656
0.037182
0.046967
0.037182
0.021526
0.013699
0.039139
0
34,952
C
A
T
C
T
T
A
C
A
G
G
C
G
C
T
G
G
A
T
G
A
G
C
T
G
C
T
G
G
A
G
G
C
C
C
C
T
G
G
G
G
A
C
C
T
G
G
A
G
A
C
C
C
T
G
C
C
C
C
G
C
T
T
A
C
T
0.009785
0.017613
0.023483
0.007828
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0.082192
0.07045
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0.050881
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0.031311
0.058708
0.050881
0.009785
0.009785
0.033268
0
34,953
C
C
C
A
A
A
G
C
C
C
G
T
G
C
C
A
T
A
G
A
A
C
A
A
G
G
T
G
A
C
C
A
C
T
G
A
G
A
G
G
T
G
G
G
A
A
C
C
A
C
A
G
G
T
G
G
A
A
A
A
C
G
C
T
T
G
0.058708
0.023483
0.043053
0.027397
0.039139
0.035225
0.011742
0.037182
0.037182
0.02544
0.046967
0.02544
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0.033268
0.005871
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0.005871
0.019569
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0.048924
0.029354
0.027397
0.027397
0.039139
0.017613
0.015656
0.048924
0
34,954
T
A
T
A
C
T
T
T
G
C
A
A
C
T
G
G
C
G
T
C
C
T
G
G
G
T
G
T
G
A
T
T
T
C
C
T
T
C
A
C
T
G
G
A
A
T
A
T
T
T
T
T
C
T
C
T
T
A
C
T
A
T
A
A
A
C
0.046967
0.027397
0.033268
0.021526
0.039139
0.046967
0.013699
0.031311
0.041096
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0.056751
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0.050881
0.041096
0.007828
0.007828
0.005871
0.017613
0.029354
0.050881
0.033268
0.029354
0.021526
0.033268
0.015656
0.009785
0.052838
0
34,955
T
A
G
A
T
C
A
C
A
A
A
A
A
A
A
G
T
G
T
G
G
A
A
T
T
T
C
C
A
T
T
T
C
G
G
T
G
C
A
G
A
A
G
G
A
C
A
G
C
C
T
C
A
A
A
A
C
A
G
T
C
A
A
G
G
T
0.066536
0.02544
0.033268
0.033268
0.039139
0.037182
0.017613
0.033268
0.035225
0.027397
0.037182
0.033268
0.019569
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0.02544
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0.060665
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0.011742
0.009785
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0.027397
0.050881
0.037182
0.029354
0.021526
0.033268
0.011742
0.013699
0.056751
0
34,956
C
A
T
G
A
T
G
A
C
C
G
T
A
T
A
G
T
G
C
A
G
G
G
G
G
T
G
A
C
A
G
A
C
G
G
C
C
A
C
G
A
A
G
C
G
G
T
C
A
T
A
G
G
C
C
A
T
C
A
C
G
G
T
C
A
T
0.052838
0.02544
0.031311
0.02544
0.043053
0.039139
0.015656
0.033268
0.033268
0.023483
0.041096
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0.023483
0.043053
0.02544
0.043053
0.064579
0.04501
0.033268
0.011742
0.011742
0.005871
0.005871
0.029354
0.041096
0.04501
0.031311
0.021526
0.037182
0.017613
0.013699
0.056751
0
34,957
G
C
A
T
C
C
A
A
A
T
G
A
A
G
T
G
A
A
A
A
A
A
A
A
A
A
T
C
T
G
A
C
T
G
A
G
A
C
A
G
C
C
T
G
C
A
T
A
T
G
T
T
A
T
G
A
A
T
T
T
G
T
T
C
T
C
0.056751
0.02544
0.027397
0.02544
0.041096
0.037182
0.013699
0.035225
0.041096
0.023483
0.039139
0.021526
0.023483
0.046967
0.02544
0.037182
0.064579
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0.035225
0.013699
0.009785
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0.009785
0.037182
0.04501
0.043053
0.029354
0.019569
0.039139
0.019569
0.007828
0.058708
0
34,958
A
T
A
C
T
T
C
C
C
C
T
G
A
G
C
T
G
A
T
G
A
G
A
T
T
G
C
A
C
G
T
A
T
G
G
A
G
G
A
A
A
C
T
A
T
C
T
T
A
G
A
G
T
A
A
G
A
G
T
A
C
A
G
G
A
A
0.043053
0.021526
0.033268
0.035225
0.058708
0.037182
0.003914
0.031311
0.035225
0.029354
0.04501
0.023483
0.027397
0.050881
0.017613
0.058708
0.060665
0.039139
0.033268
0.001957
0
0.005871
0.015656
0.031311
0.041096
0.015656
0.043053
0.015656
0.033268
0.033268
0.031311
0.046967
0
34,959
C
T
G
T
G
G
A
C
T
G
C
T
G
G
T
T
C
T
G
G
C
A
T
C
C
T
G
G
A
T
C
A
T
G
A
G
T
G
T
T
C
T
G
A
A
T
T
C
C
A
T
G
T
T
A
C
A
A
A
G
C
T
T
A
A
C
0.041096
0.02544
0.035225
0.02544
0.058708
0.035225
0.007828
0.031311
0.043053
0.021526
0.037182
0.019569
0.041096
0.054795
0.02544
0.048924
0.056751
0.04501
0.023483
0.009785
0.003914
0.005871
0.019569
0.02544
0.035225
0.029354
0.035225
0.019569
0.037182
0.029354
0.02544
0.046967
0
34,960
C
C
A
T
G
T
A
C
C
T
G
G
T
C
A
C
T
G
T
G
C
T
C
G
G
G
A
A
C
C
T
G
C
T
C
A
T
C
A
T
C
C
T
G
G
C
C
A
C
A
A
T
C
T
C
A
G
A
C
T
C
C
C
A
C
A
0.041096
0.031311
0.033268
0.035225
0.058708
0.031311
0.003914
0.023483
0.076321
0.011742
0.035225
0.023483
0.037182
0.052838
0.031311
0.039139
0.046967
0.04501
0.019569
0.009785
0.005871
0
0.015656
0.048924
0.052838
0.027397
0.023483
0.019569
0.041096
0.019569
0.015656
0.043053
0
34,961
C
C
T
G
G
T
C
A
C
T
G
T
G
C
T
C
G
G
G
A
A
T
C
T
G
C
T
C
A
T
C
A
T
C
C
T
G
G
C
C
A
C
A
A
T
C
T
C
A
G
A
C
T
C
C
C
A
C
C
T
C
C
A
C
A
C
0.062622
0.02544
0.023483
0.039139
0.050881
0.027397
0.001957
0.019569
0.062622
0.023483
0.039139
0.02544
0.041096
0.046967
0.02544
0.031311
0.064579
0.048924
0.027397
0.003914
0.005871
0.003914
0.011742
0.04501
0.033268
0.029354
0.033268
0.021526
0.04501
0.015656
0.029354
0.035225
0
34,962
A
A
C
C
T
T
G
T
C
C
A
G
A
G
G
C
T
G
G
T
T
C
A
T
G
A
G
G
T
C
C
A
C
G
G
C
T
T
G
G
A
G
C
C
G
C
T
C
C
T
T
G
A
A
G
C
A
G
A
A
G
T
T
C
A
T
0.046967
0.019569
0.029354
0.013699
0.02544
0.035225
0.013699
0.037182
0.046967
0.035225
0.056751
0.011742
0.011742
0.017613
0.023483
0.04501
0.066536
0.054795
0.052838
0.011742
0.007828
0.009785
0.017613
0.062622
0.029354
0.035225
0.035225
0.041096
0.048924
0.011742
0.009785
0.035225
0
34,963
C
A
T
G
C
C
C
G
A
T
G
T
T
C
T
T
G
C
A
G
T
T
G
A
G
G
C
C
C
C
A
G
C
T
G
A
G
G
T
T
C
T
T
G
T
G
C
G
T
G
G
C
G
A
G
C
A
G
C
T
C
G
T
C
C
G
0.023483
0.019569
0.015656
0.003914
0.035225
0.035225
0.027397
0.007828
0.021526
0.056751
0.058708
0.001957
0.013699
0.019569
0.015656
0.052838
0.080235
0.052838
0.060665
0.027397
0.013699
0.064579
0.009785
0.039139
0.019569
0.023483
0.060665
0.064579
0.039139
0.009785
0.005871
0.019569
0
34,964
C
G
C
C
G
C
C
G
C
C
G
C
G
C
A
G
C
A
A
G
A
G
C
A
G
C
G
C
G
G
A
C
C
C
C
T
A
G
T
G
A
C
C
C
C
A
G
C
G
T
C
C
C
C
C
G
C
C
C
C
A
G
C
C
A
A
0.011742
0.021526
0.017613
0.023483
0.023483
0.037182
0.029354
0.013699
0.019569
0.050881
0.052838
0.02544
0.019569
0.02544
0.023483
0.041096
0.058708
0.050881
0.054795
0.023483
0.011742
0.060665
0.023483
0.035225
0.009785
0.02544
0.056751
0.048924
0.041096
0.015656
0.029354
0.017613
0
34,965
G
T
A
C
A
T
G
G
G
T
G
T
G
T
G
G
A
G
G
T
G
A
G
A
G
T
C
C
G
T
G
A
T
G
A
T
G
G
C
C
A
G
G
A
T
A
A
T
G
A
G
G
G
C
A
T
T
T
C
C
A
A
T
G
A
A
0.033268
0.02544
0.029354
0.021526
0.043053
0.04501
0.011742
0.017613
0.054795
0.031311
0.041096
0.015656
0.02544
0.050881
0.019569
0.048924
0.050881
0.074364
0.033268
0.011742
0.013699
0.005871
0.011742
0.050881
0.048924
0.027397
0.017613
0.031311
0.050881
0.015656
0.007828
0.033268
0
34,966
T
T
G
C
T
T
T
T
G
G
C
A
T
T
G
T
C
G
T
G
G
G
C
A
C
C
A
G
C
C
C
A
T
T
C
T
C
C
T
G
C
A
T
C
C
T
T
C
T
C
T
C
G
T
A
C
A
T
C
C
G
C
A
T
T
C
0.019569
0.015656
0.041096
0.011742
0.054795
0.031311
0.011742
0.019569
0.04501
0.048924
0.039139
0.007828
0.029354
0.048924
0.02544
0.054795
0.056751
0.054795
0.050881
0.015656
0.007828
0.011742
0.007828
0.046967
0.029354
0.02544
0.039139
0.033268
0.04501
0.021526
0.013699
0.035225
0
34,967
G
C
A
A
G
T
G
G
A
A
A
G
C
C
T
T
C
T
C
C
A
C
C
T
G
T
G
G
C
T
T
A
C
A
C
C
T
C
A
C
T
G
T
G
G
T
G
T
C
A
C
T
G
T
C
C
T
A
T
G
G
G
A
C
C
T
0.023483
0.019569
0.04501
0.011742
0.054795
0.023483
0.011742
0.021526
0.039139
0.043053
0.046967
0.013699
0.033268
0.043053
0.023483
0.048924
0.056751
0.048924
0.050881
0.019569
0.009785
0.009785
0.011742
0.037182
0.035225
0.023483
0.035225
0.04501
0.046967
0.017613
0.015656
0.033268
0
34,968
C
A
T
C
C
C
C
A
T
G
C
T
C
A
A
C
C
C
C
T
T
T
A
T
C
T
A
C
A
G
C
A
T
A
C
G
G
A
A
C
A
A
G
G
A
T
A
T
G
A
A
G
G
C
A
G
C
C
C
T
G
G
G
G
A
C
0.023483
0.023483
0.039139
0.013699
0.060665
0.017613
0.009785
0.02544
0.039139
0.035225
0.046967
0.021526
0.039139
0.050881
0.021526
0.041096
0.052838
0.050881
0.056751
0.011742
0.005871
0.003914
0.021526
0.033268
0.035225
0.023483
0.029354
0.033268
0.060665
0.02544
0.021526
0.02544
0
34,969
G
C
C
C
C
A
G
A
G
T
G
C
G
G
C
C
G
G
G
G
G
T
G
C
C
C
G
G
G
C
T
G
C
G
G
G
A
C
C
C
A
C
C
T
C
G
T
A
G
G
G
C
C
G
G
A
A
G
G
A
G
G
T
G
G
T
0
0.005871
0.013699
0
0.007828
0.039139
0.013699
0.013699
0.009785
0.052838
0.064579
0
0.005871
0.005871
0.003914
0.037182
0.078278
0.052838
0.125245
0.078278
0.015656
0.056751
0.005871
0.04501
0.013699
0.019569
0.048924
0.11546
0.041096
0.011742
0.001957
0.015656
0
34,970
A
G
G
G
G
C
T
G
G
G
G
A
C
A
T
G
T
T
A
T
G
G
A
C
T
C
A
G
C
G
T
C
C
T
C
C
C
T
G
T
C
C
C
T
G
C
A
G
G
T
C
C
G
G
T
G
T
T
T
G
T
G
G
A
G
T
0.015656
0.015656
0.021526
0.009785
0.041096
0.039139
0.011742
0.015656
0.023483
0.04501
0.056751
0.007828
0.019569
0.033268
0.019569
0.052838
0.066536
0.064579
0.084149
0.029354
0.011742
0.017613
0.005871
0.046967
0.021526
0.029354
0.041096
0.052838
0.056751
0.009785
0.007828
0.02544
0
34,971
G
G
C
A
G
T
C
C
C
A
G
G
A
C
A
T
G
G
C
G
A
G
G
A
G
T
A
C
C
C
G
G
C
G
G
C
T
G
G
G
G
C
A
C
A
C
A
G
C
A
G
C
C
C
C
C
C
A
A
A
G
G
C
C
C
T
0.001957
0.009785
0.015656
0.005871
0.019569
0.035225
0.005871
0.023483
0.011742
0.052838
0.064579
0
0.009785
0.011742
0.011742
0.041096
0.091977
0.080235
0.136986
0.035225
0.011742
0.02544
0.007828
0.037182
0.015656
0.021526
0.039139
0.099804
0.043053
0.011742
0.003914
0.017613
0
34,972
T
G
A
G
A
G
A
G
T
C
T
C
A
C
T
C
T
G
T
T
G
C
C
C
A
G
G
C
T
G
G
A
T
T
G
C
A
A
T
G
G
C
A
C
T
G
T
G
C
C
A
C
T
G
C
T
G
A
C
A
C
C
C
A
G
C
0.068493
0.02544
0.023483
0.041096
0.033268
0.031311
0.007828
0.029354
0.027397
0.027397
0.054795
0.019569
0.015656
0.02544
0.043053
0.039139
0.052838
0.066536
0.058708
0.001957
0.003914
0.001957
0.021526
0.041096
0.015656
0.02544
0.031311
0.054795
0.037182
0.013699
0.031311
0.029354
0
34,973
G
C
A
A
G
G
T
G
A
G
C
C
C
C
A
G
C
C
C
T
T
G
G
T
C
C
A
C
T
G
G
G
T
G
T
C
A
G
C
A
G
T
G
G
C
A
C
A
G
T
G
C
C
A
T
T
G
C
A
A
T
C
C
A
G
G
0.058708
0.023483
0.027397
0.039139
0.031311
0.029354
0.009785
0.031311
0.023483
0.027397
0.056751
0.019569
0.017613
0.02544
0.04501
0.041096
0.054795
0.068493
0.056751
0.003914
0.003914
0.001957
0.017613
0.039139
0.017613
0.023483
0.035225
0.060665
0.039139
0.013699
0.02544
0.031311
0
34,974
A
C
A
G
G
T
G
C
A
G
C
G
G
A
A
A
C
C
A
C
C
C
A
C
C
A
G
G
T
C
C
A
C
G
C
A
G
G
T
G
C
C
A
T
T
G
T
G
T
A
G
G
C
A
C
C
G
G
G
G
C
C
C
T
G
T
0.009785
0.017613
0.013699
0.015656
0.031311
0.04501
0.015656
0.011742
0.021526
0.037182
0.064579
0.005871
0.015656
0.033268
0.019569
0.043053
0.074364
0.054795
0.088063
0.027397
0.015656
0.037182
0.005871
0.041096
0.021526
0.031311
0.052838
0.060665
0.041096
0.009785
0.005871
0.031311
0
34,975
T
C
C
G
C
T
C
C
A
T
C
C
A
G
G
G
G
G
A
C
A
A
A
G
G
C
A
A
T
A
G
G
C
C
C
C
A
G
T
C
T
G
G
A
C
G
C
A
G
C
G
A
C
C
C
C
C
G
T
T
T
T
G
A
C
G
0.007828
0.007828
0.021526
0.005871
0.037182
0.033268
0.015656
0.029354
0.019569
0.043053
0.048924
0.003914
0.017613
0.027397
0.017613
0.07045
0.060665
0.068493
0.099804
0.029354
0.013699
0.02544
0.013699
0.04501
0.015656
0.02544
0.04501
0.066536
0.046967
0.011742
0.001957
0.023483
0