Datasets:
TabBioMed
/
vep_pathogenic_coding

Dataset card Data Studio Files
xet
 Community
row_idx
int64
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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
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T
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G
A
A
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C
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T
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G
A
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T
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T
G
G
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C
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C
A
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C
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A
A
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G
A
T
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A
G
G
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A
A
A
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A
C
A
C
A
A
A
A
G
A
G
G
T
T
A
T
A
A
T
G
G
A
C
T
T
A
A
C
C
A
A
T
G
0.107632
0.039139
0.052838
0.054795
0.058708
0.023483
0.003914
0.02544
0.046967
0.019569
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0.021526
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0.009785
0
0
0
0.015656
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0.048924
0.015656
0.021526
0.013699
0.015656
0.027397
0.043053
0.046967
0
35,093
A
T
G
T
G
A
A
G
A
T
T
G
T
G
G
C
A
A
A
G
A
A
T
T
A
A
A
G
T
A
T
T
C
C
T
C
T
A
C
C
C
T
T
A
C
T
G
C
A
C
A
T
A
A
G
A
G
A
A
T
T
C
A
T
A
T
0.04501
0.015656
0.064579
0.056751
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0.062622
0.005871
0.027397
0.019569
0.029354
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0.039139
0.039139
0
35,094
A
T
A
A
A
G
G
A
G
T
G
A
G
G
A
T
G
A
A
A
T
A
A
A
T
G
C
T
T
T
G
C
C
A
C
A
T
T
T
A
T
C
A
C
A
C
T
T
G
T
A
G
G
G
T
T
T
C
T
C
T
C
C
A
G
T
0.052838
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0.07045
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0.060665
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0.031311
0.052838
0.02544
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0.019569
0.013699
0
0.005871
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0.056751
0.013699
0.017613
0.021526
0.027397
0.035225
0.039139
0.048924
0
35,095
C
A
C
A
T
T
C
T
T
C
A
C
A
A
A
T
G
T
A
G
G
G
T
T
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C
T
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C
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C
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A
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A
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C
T
T
A
T
G
T
G
T
A
G
T
A
A
A
G
C
T
A
G
A
G
G
0.086106
0.02544
0.060665
0.037182
0.056751
0.029354
0.007828
0.033268
0.050881
0.019569
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0.050881
0.019569
0.052838
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0.039139
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0.02544
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0.007828
0.003914
0
0.029354
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0.048924
0.009785
0.013699
0.013699
0.021526
0.052838
0.043053
0.037182
0
35,096
T
G
T
A
G
T
A
A
G
G
G
T
A
G
A
G
G
G
G
C
A
C
T
T
A
A
A
G
C
C
T
T
T
G
C
C
A
C
A
T
T
C
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C
A
C
A
T
T
T
G
T
A
G
G
G
T
T
T
C
T
C
T
C
C
0.068493
0.019569
0.07045
0.048924
0.048924
0.015656
0.003914
0.031311
0.048924
0.027397
0.043053
0.041096
0.013699
0.048924
0.031311
0.039139
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0.02544
0.019569
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0.005871
0.029354
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0.054795
0.005871
0.029354
0.027397
0.027397
0.035225
0.050881
0.031311
0
35,097
A
G
T
T
G
A
A
G
G
C
T
T
T
G
C
C
A
C
A
T
T
C
T
T
C
A
C
A
T
T
T
G
T
A
G
G
G
T
T
T
C
T
C
T
C
C
A
C
T
A
T
G
A
A
T
T
A
T
C
T
T
G
T
G
T
C
0.039139
0.013699
0.076321
0.043053
0.062622
0.017613
0
0.035225
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0.060665
0.005871
0.019569
0.027397
0.029354
0.048924
0.046967
0.029354
0
35,098
G
T
A
A
T
G
T
G
C
T
T
T
T
A
T
T
G
T
T
T
C
T
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C
A
G
T
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A
C
G
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G
T
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C
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C
A
T
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G
C
C
C
G
A
G
A
T
C
T
T
T
G
G
C
C
A
G
A
G
G
0.105675
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0.046967
0.060665
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0.013699
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0.043053
0.041096
0.017613
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0.066536
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0.02544
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0
0.015656
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0.019569
0.02544
0.015656
0.011742
0.035225
0.054795
0.04501
0
35,099
C
A
C
A
C
A
A
T
T
G
G
G
C
C
G
G
G
C
G
G
G
G
T
G
C
C
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C
A
T
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C
C
T
G
T
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A
T
T
C
C
A
G
T
A
C
T
T
T
G
G
G
A
G
G
C
C
G
A
G
G
C
A
G
T
0.041096
0.033268
0.02544
0.031311
0.029354
0.046967
0.001957
0.037182
0.037182
0.033268
0.050881
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0.011742
0.029354
0.037182
0.033268
0.072407
0.056751
0.035225
0.011742
0.007828
0.005871
0.017613
0.043053
0.033268
0.021526
0.043053
0.054795
0.021526
0.027397
0.019569
0.043053
0
35,100
G
T
G
T
A
G
T
A
A
G
G
T
T
A
G
A
G
A
A
A
T
G
C
T
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A
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C
T
T
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G
T
C
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A
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C
A
C
A
T
T
T
G
T
A
G
A
A
T
T
T
C
T
C
T
G
0.066536
0.013699
0.060665
0.054795
0.060665
0.023483
0
0.031311
0.062622
0.02544
0.033268
0.029354
0.019569
0.056751
0.021526
0.048924
0.019569
0.027397
0.009785
0.001957
0
0.001957
0.027397
0.043053
0.060665
0.007828
0.017613
0.013699
0.02544
0.04501
0.046967
0.043053
0
35,101
T
C
A
G
T
A
C
C
A
C
T
T
T
T
T
G
G
A
A
A
G
A
A
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C
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C
A
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C
T
C
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C
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C
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G
G
C
C
A
A
A
G
G
T
C
T
T
G
G
G
C
A
A
A
A
T
G
A
T
0.117417
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0.050881
0.058708
0.064579
0.017613
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0.035225
0.033268
0.009785
0.019569
0.078278
0.019569
0.048924
0.052838
0.027397
0.023483
0.02544
0.009785
0.001957
0
0
0.007828
0.015656
0.046967
0.019569
0.015656
0.009785
0.021526
0.035225
0.046967
0.046967
0
35,102
G
T
T
C
T
C
A
T
T
T
T
G
C
C
C
A
A
G
A
C
C
T
T
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G
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C
C
A
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A
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C
A
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A
G
C
A
T
G
A
A
A
G
A
T
T
C
T
T
T
C
C
A
A
A
A
A
G
T
G
G
T
A
G
0.11546
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0.050881
0.056751
0.064579
0.017613
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0.035225
0.033268
0.009785
0.019569
0.074364
0.019569
0.048924
0.052838
0.027397
0.02544
0.027397
0.013699
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0
0
0.007828
0.015656
0.046967
0.019569
0.015656
0.009785
0.021526
0.035225
0.046967
0.046967
0
35,103
C
T
G
T
C
T
G
G
A
G
C
A
A
G
G
A
A
G
A
A
A
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C
C
T
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G
A
C
C
A
T
G
A
A
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A
G
A
A
A
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G
A
G
A
T
G
A
T
A
G
C
C
A
A
A
C
C
C
T
C
A
G
C
0.123288
0.033268
0.050881
0.068493
0.052838
0.027397
0
0.021526
0.048924
0.031311
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0.037182
0.023483
0.023483
0.04501
0.023483
0.033268
0.023483
0.017613
0
0
0
0.027397
0.021526
0.041096
0.015656
0.017613
0.009785
0.021526
0.029354
0.066536
0.031311
0
35,104
A
T
C
T
G
G
A
G
C
A
A
G
G
A
A
A
A
A
A
A
C
C
T
T
C
G
A
C
T
A
T
G
C
A
G
A
G
A
C
A
T
G
A
G
A
T
G
G
T
A
G
C
C
A
A
C
C
C
C
T
C
A
G
G
T
A
0.119374
0.033268
0.041096
0.064579
0.062622
0.021526
0
0.021526
0.050881
0.029354
0.029354
0.033268
0.019569
0.033268
0.052838
0.027397
0.037182
0.027397
0.011742
0
0.003914
0
0.023483
0.029354
0.043053
0.019569
0.02544
0.015656
0.019569
0.02544
0.043053
0.035225
0
35,105
G
G
T
T
A
A
A
A
G
C
T
T
T
G
C
C
A
C
A
T
T
C
T
G
T
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A
A
T
T
T
G
C
A
A
G
G
G
T
T
T
T
T
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C
C
A
G
T
A
T
G
T
C
T
T
A
T
C
T
T
A
T
G
T
A
0.107632
0.035225
0.054795
0.04501
0.058708
0.029354
0.001957
0.033268
0.043053
0.017613
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0.04501
0.015656
0.046967
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0.033268
0.023483
0.027397
0.009785
0.011742
0
0.001957
0.015656
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0.041096
0.017613
0.02544
0.013699
0.023483
0.037182
0.054795
0.033268
0
35,106
G
A
A
T
T
C
T
C
T
T
A
T
G
T
G
T
A
G
T
A
A
G
G
A
T
A
G
A
G
G
A
G
C
G
C
T
T
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A
A
G
G
C
C
T
T
G
C
C
A
C
A
T
T
C
T
T
C
A
C
A
T
T
T
G
T
0.058708
0.02544
0.064579
0.04501
0.060665
0.035225
0.001957
0.033268
0.058708
0.013699
0.04501
0.037182
0.005871
0.04501
0.02544
0.041096
0.015656
0.02544
0.011742
0.011742
0
0.005871
0.027397
0.043053
0.060665
0.007828
0.009785
0.021526
0.027397
0.056751
0.046967
0.031311
0
35,107
C
C
A
A
C
A
G
A
A
G
A
T
C
T
T
T
A
C
C
T
T
C
T
G
A
A
A
C
T
G
G
T
T
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A
T
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A
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C
T
T
G
A
A
G
A
G
G
G
C
T
G
G
G
C
G
C
T
G
A
G
G
C
0.050881
0.031311
0.037182
0.023483
0.019569
0.027397
0.015656
0.041096
0.039139
0.035225
0.050881
0.041096
0.021526
0.011742
0.037182
0.029354
0.056751
0.039139
0.037182
0.009785
0.013699
0.011742
0.029354
0.043053
0.027397
0.027397
0.037182
0.04501
0.029354
0.015656
0.027397
0.037182
0
35,108
C
A
G
T
C
A
G
C
T
T
A
C
T
T
G
A
G
A
C
T
A
G
G
A
G
T
T
G
A
A
G
A
T
C
A
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C
C
T
G
A
G
C
A
A
C
A
T
A
G
T
G
A
G
A
C
A
C
T
G
C
A
T
A
C
C
0.127202
0.031311
0.029354
0.080235
0.039139
0.011742
0
0.037182
0.023483
0.017613
0.02544
0.135029
0.021526
0.041096
0.027397
0.017613
0.027397
0.013699
0.005871
0
0
0
0.027397
0.019569
0.017613
0.011742
0.023483
0.017613
0.009785
0.027397
0.09589
0.037182
0
35,109
C
T
C
A
G
C
C
T
C
T
C
A
A
G
T
A
G
C
T
G
A
G
A
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A
C
A
G
G
C
A
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G
C
G
C
C
A
C
C
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G
C
C
C
G
G
C
T
C
A
T
T
T
T
T
G
T
A
T
T
T
T
C
0.080235
0.02544
0.019569
0.056751
0.031311
0.027397
0.003914
0.027397
0.021526
0.039139
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0.019569
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0.035225
0.013699
0.039139
0.041096
0.029354
0.019569
0.029354
0.046967
0
35,110
G
C
C
A
A
G
G
C
G
G
G
T
G
G
A
T
C
A
C
A
T
G
A
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G
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C
A
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C
G
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C
C
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C
G
T
G
T
C
C
A
A
C
A
T
G
G
T
G
A
A
A
C
C
C
A
0.07045
0.023483
0.021526
0.056751
0.033268
0.029354
0.007828
0.031311
0.02544
0.033268
0.033268
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0.017613
0.046967
0.035225
0.029354
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0.021526
0.011742
0.009785
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0.009785
0.041096
0.031311
0.015656
0.039139
0.035225
0.027397
0.033268
0.035225
0.043053
0
35,111
A
A
T
C
T
T
T
T
A
T
A
T
T
C
T
G
C
T
C
C
G
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A
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A
C
A
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A
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C
T
G
A
A
A
G
A
A
A
C
C
0.113503
0.023483
0.043053
0.068493
0.060665
0.015656
0
0.035225
0.039139
0.017613
0.015656
0.056751
0.019569
0.062622
0.039139
0.031311
0.021526
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0.009785
0.003914
0.001957
0.001957
0.019569
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0.033268
0.023483
0.023483
0.015656
0.017613
0.033268
0.062622
0.039139
0
35,112
T
C
T
T
A
C
A
C
T
C
A
T
C
C
A
T
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A
T
T
T
T
C
C
A
A
0.113503
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0
0.033268
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0
35,113
T
C
T
G
C
T
A
T
G
T
T
C
A
G
T
T
A
G
G
C
A
T
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A
C
A
T
T
T
T
G
T
A
C
A
T
T
T
G
A
A
A
G
G
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0
35,114
A
T
G
T
G
A
A
G
A
A
T
G
T
G
G
C
A
A
A
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A
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C
C
A
T
A
A
G
A
T
A
A
T
T
C
A
T
A
C
0.088063
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0
35,115
T
C
T
A
C
A
G
C
T
T
T
A
G
G
A
A
G
C
C
A
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A
G
T
C
C
A
A
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A
T
C
C
A
G
T
C
T
G
A
T
0.103718
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0
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0
35,116
A
T
T
T
G
T
A
G
G
G
T
T
T
C
T
C
T
C
C
A
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G
G
G
T
T
G
A
A
G
A
C
C
A
G
T
T
A
A
A
G
C
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0
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0
35,117
T
C
A
T
G
C
C
T
C
A
G
C
C
T
C
T
G
G
A
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C
C
A
T
G
C
C
C
A
T
G
C
C
C
A
G
C
T
G
A
T
0.113503
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0
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0
35,118
C
T
T
C
C
T
T
G
A
G
A
G
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A
T
A
C
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A
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A
A
T
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A
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C
C
A
G
A
A
G
C
T
G
A
C
0.078278
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0
35,119
G
A
A
C
T
A
T
T
T
T
G
C
T
C
T
G
G
G
T
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T
G
T
G
A
C
C
T
C
C
T
T
T
G
T
G
C
A
A
C
T
0.105675
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0
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0.050881
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0
35,120
T
C
C
T
T
T
G
T
G
C
A
A
C
T
T
A
T
G
C
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A
T
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T
C
C
A
C
A
T
T
T
T
C
C
A
T
A
T
C
C
0.103718
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0
0
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0
35,121
C
C
C
C
T
T
G
A
C
A
G
G
A
T
A
C
A
C
T
C
C
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A
A
A
A
T
A
A
A
C
C
A
G
A
A
G
C
T
G
A
T
T
0.09002
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0
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0
35,122
A
G
A
A
A
A
T
A
C
T
A
A
A
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G
C
T
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T
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C
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T
T
T
C
T
C
C
A
T
T
A
T
G
A
A
T
T
A
T
C
A
0.068493
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0.054795
0.064579
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0.02544
0
0.031311
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0.019569
0
0
0
0.033268
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0.062622
0.007828
0.015656
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0.017613
0.035225
0.054795
0.041096
0
35,123
A
A
T
G
T
G
G
C
A
A
A
G
C
T
T
A
T
A
A
G
G
A
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T
C
T
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C
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T
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A
A
A
G
A
A
T
T
C
A
T
A
C
T
G
G
A
G
A
G
G
0.07045
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0
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0
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0.013699
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0.015656
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0
35,124
A
T
A
A
G
A
A
A
A
T
T
C
A
T
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G
G
A
T
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C
C
C
A
G
C
A
C
T
T
T
G
G
G
A
G
G
C
A
G
A
T
0.088063
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0.029354
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0.031311
0.039139
0
35,125
T
G
G
C
A
A
A
G
C
T
T
T
T
T
A
C
C
G
A
T
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A
A
G
T
C
A
T
A
C
T
G
G
A
G
A
G
A
A
A
T
T
0.064579
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0.054795
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0.023483
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0
35,126
A
G
G
G
C
A
T
C
C
A
C
T
T
G
C
T
C
C
C
T
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A
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G
G
G
T
C
A
T
C
C
T
A
C
G
G
G
A
G
A
A
A
A
T
C
0.097847
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0.041096
0
35,127
A
T
G
C
C
T
G
T
G
A
G
C
T
G
G
G
T
C
C
A
A
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A
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G
C
C
A
A
A
T
G
C
A
T
A
T
A
T
G
A
C
A
G
T
0.056751
0.017613
0.033268
0.039139
0.062622
0.037182
0
0.02544
0.046967
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0.027397
0.031311
0.02544
0.015656
0.029354
0.039139
0.046967
0
35,128
T
A
C
A
C
A
T
A
A
G
A
A
A
A
T
T
C
A
T
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C
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A
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A
A
T
G
T
G
G
C
A
A
A
G
G
C
T
T
C
A
A
0.086106
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0.041096
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0
0
0.001957
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0.072407
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0.017613
0.017613
0.027397
0.029354
0.039139
0.046967
0
35,129
T
G
A
A
G
A
A
T
G
T
G
G
C
A
A
A
G
C
C
T
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A
C
A
T
A
A
G
G
C
A
A
T
T
C
A
T
G
C
T
G
T
0.048924
0.02544
0.072407
0.054795
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0
0.035225
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0.021526
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0.066536
0.029354
0
35,130
T
T
T
G
C
C
A
C
A
T
T
C
T
T
C
A
C
A
T
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A
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C
T
T
A
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T
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A
G
T
A
A
G
G
A
T
0.050881
0.023483
0.074364
0.056751
0.046967
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0
0.035225
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0
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0
0.02544
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0.02544
0.029354
0.023483
0.048924
0.068493
0.027397
0
35,131
T
A
A
A
C
T
C
C
T
C
C
T
C
C
C
G
G
G
T
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C
A
A
G
T
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G
C
A
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G
G
A
T
T
A
C
A
G
C
0.107632
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0.019569
0.021526
0.031311
0.017613
0.017613
0.041096
0.043053
0
35,132
T
G
T
T
A
A
A
C
T
C
T
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G
T
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G
T
A
C
T
0.103718
0.041096
0.046967
0.07045
0.050881
0.013699
0.007828
0.031311
0.060665
0.011742
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0.062622
0.021526
0.052838
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0
0
0
0.023483
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0.050881
0.013699
0.027397
0.011742
0.013699
0.027397
0.058708
0.039139
0
35,133
T
C
T
C
A
T
G
T
C
T
C
T
T
C
A
T
A
T
T
C
C
A
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C
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C
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A
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A
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A
A
A
T
G
A
T
C
A
G
G
T
C
T
G
G
C
T
T
A
T
0.091977
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0.056751
0.066536
0.04501
0.013699
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0.054795
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0.017613
0
0
0
0.017613
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0.058708
0.017613
0.019569
0.009785
0.031311
0.019569
0.066536
0.037182
0
35,134
A
A
T
T
T
T
T
T
T
T
G
C
C
C
T
G
C
T
T
T
G
G
C
C
A
A
A
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G
T
C
T
C
G
G
G
C
A
A
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A
A
C
A
T
A
C
A
A
C
T
G
A
A
A
G
A
A
A
T
T
0.121331
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0.04501
0.07045
0.068493
0.011742
0.007828
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0.019569
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0.039139
0.023483
0.02544
0.011742
0.007828
0.043053
0.062622
0.039139
0
35,135
A
C
T
G
T
A
A
A
T
T
T
T
C
A
C
A
T
C
C
A
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A
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C
A
G
T
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C
T
T
T
T
T
G
G
A
A
A
T
A
A
T
T
T
T
T
T
G
0.136986
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0.050881
0.023483
0.021526
0.007828
0.009785
0.043053
0.054795
0.043053
0
35,136
C
A
C
A
T
T
C
T
T
T
A
C
A
T
T
T
G
T
A
G
G
G
T
T
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C
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A
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T
A
T
G
T
T
G
A
G
C
T
A
A
G
T
G
T
G
A
A
G
0.097847
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0.064579
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0.046967
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0.060665
0.017613
0.019569
0.007828
0.019569
0.041096
0.048924
0.041096
0
35,137
C
C
C
A
C
A
T
T
C
T
T
T
A
C
A
T
T
T
G
T
A
G
G
G
T
T
T
C
T
C
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C
A
C
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A
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A
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T
T
T
A
T
G
T
T
G
A
G
C
T
A
A
G
T
G
T
G
T
0.097847
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0.064579
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0.060665
0.017613
0.019569
0.007828
0.019569
0.039139
0.046967
0.041096
0
35,138
G
T
G
T
G
A
G
A
G
C
C
G
G
T
T
A
A
A
G
G
C
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C
A
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G
G
G
T
T
T
C
T
T
T
C
C
A
G
T
A
T
G
A
A
G
0.091977
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0.011742
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0.021526
0.033268
0.066536
0.013699
0.021526
0.011742
0.019569
0.035225
0.043053
0.043053
0
35,139
A
T
G
T
G
T
A
G
T
A
A
G
G
T
G
T
G
A
G
A
G
C
C
G
G
T
T
A
A
A
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G
C
T
T
T
T
C
C
A
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A
C
T
C
T
T
C
G
C
A
T
T
T
G
T
A
G
G
G
T
T
T
C
T
A
0.093933
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0.023483
0.013699
0.019569
0.035225
0.043053
0.039139
0
35,140
T
A
A
G
G
T
G
G
G
A
T
A
A
C
T
G
G
C
T
A
A
A
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G
C
C
T
T
A
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A
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T
C
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C
A
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A
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T
G
T
A
G
A
A
T
T
T
C
T
C
T
C
C
A
G
T
A
T
0.050881
0.021526
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0.023483
0
0.029354
0.064579
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0
0
0.029354
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0.021526
0.02544
0.019569
0.04501
0.048924
0.031311
0
35,141
C
T
A
C
A
C
A
T
A
A
G
A
G
A
A
T
T
C
A
T
T
C
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G
A
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A
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G
A
A
G
A
A
T
G
T
G
G
C
A
A
A
G
C
T
T
T
T
A
0.050881
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0.001957
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0
0.033268
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0.005871
0.017613
0.023483
0.019569
0.04501
0.050881
0.033268
0
35,142
A
G
G
A
T
T
G
T
T
T
A
A
A
A
G
C
T
T
T
G
C
C
A
C
A
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C
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C
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C
T
T
G
T
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G
G
G
T
T
T
C
T
C
T
C
C
A
G
A
A
T
G
A
A
T
T
C
T
C
T
0.050881
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0.064579
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0
0.031311
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0.060665
0.005871
0.017613
0.023483
0.019569
0.04501
0.050881
0.035225
0
35,143
T
C
A
C
C
A
G
C
A
C
A
A
T
T
T
C
T
T
T
T
A
T
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G
G
A
A
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C
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C
A
A
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G
T
C
A
C
A
A
G
C
A
T
T
G
T
T
A
C
A
A
C
T
G
0.074364
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0
0.035225
0.052838
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0
0
0
0.017613
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0.052838
0.007828
0.023483
0.013699
0.017613
0.037182
0.054795
0.039139
0
35,144
G
T
T
T
C
T
T
C
C
C
A
G
T
A
T
A
A
A
T
T
A
T
C
T
T
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T
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T
T
T
C
C
T
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A
G
G
G
T
T
G
A
G
G
A
A
T
T
G
T
T
A
A
A
A
G
C
T
T
T
G
C
C
A
A
0.09002
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0.066536
0.060665
0.052838
0.017613
0.001957
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0.019569
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0
0.001957
0
0.02544
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0.068493
0.005871
0.017613
0.013699
0.029354
0.031311
0.056751
0.037182
0
35,145
G
C
C
A
C
A
T
T
C
T
T
C
A
C
A
T
T
T
G
T
A
G
G
G
T
T
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C
T
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C
A
G
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A
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C
T
T
T
A
T
G
T
C
T
A
G
T
A
A
G
G
T
G
T
G
T
0.082192
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0.064579
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0.050881
0.029354
0
0.033268
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0.02544
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0.02544
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0.027397
0.033268
0.021526
0
0
0
0.027397
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0.064579
0.009785
0.011742
0.017613
0.019569
0.041096
0.052838
0.043053
0
35,146
T
T
A
T
C
T
T
A
T
G
T
T
T
C
A
T
A
A
G
G
G
T
T
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T
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C
T
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C
C
A
C
A
T
T
C
T
T
C
A
C
A
T
T
T
G
T
A
G
C
0.091977
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0.074364
0.058708
0.050881
0.021526
0
0.019569
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0
0
0
0.021526
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0.072407
0.003914
0.021526
0.017613
0.015656
0.031311
0.054795
0.041096
0
35,147
A
T
A
C
T
G
A
A
G
A
G
A
A
A
C
C
C
T
A
C
A
A
A
T
A
T
G
A
A
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A
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C
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C
A
A
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C
T
T
T
T
A
G
C
A
A
T
T
T
G
T
C
A
G
C
C
C
T
T
A
0.088063
0.027397
0.064579
0.056751
0.046967
0.023483
0.001957
0.021526
0.050881
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0.019569
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0.064579
0.009785
0.033268
0.017613
0.013699
0.033268
0.048924
0.041096
0
35,148
T
G
G
C
A
A
A
G
C
C
T
T
T
A
A
A
T
G
G
T
T
C
T
C
A
A
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C
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T
T
A
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A
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A
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A
A
T
T
C
A
T
A
C
T
G
A
A
G
A
C
A
A
A
C
G
0.09589
0.039139
0.060665
0.076321
0.052838
0.017613
0.003914
0.027397
0.048924
0.015656
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0.062622
0.017613
0.054795
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0.011742
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0.013699
0
0
0
0.023483
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0.068493
0.007828
0.017613
0.009785
0.011742
0.023483
0.062622
0.048924
0
35,149
A
A
G
A
T
T
G
T
G
A
A
A
G
T
G
T
C
A
A
T
G
A
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G
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C
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C
T
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A
T
A
A
T
A
A
A
C
T
T
A
A
C
C
A
A
T
G
T
T
0.093933
0.02544
0.062622
0.080235
0.046967
0.009785
0.007828
0.029354
0.060665
0.017613
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0.060665
0.015656
0.021526
0.009785
0.009785
0.023483
0.066536
0.04501
0
35,150
T
T
T
G
T
T
G
T
G
T
T
T
T
T
C
A
G
G
G
A
T
C
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T
A
G
A
A
T
T
C
G
C
T
C
T
G
G
A
G
G
A
G
C
0.074364
0.033268
0.027397
0.064579
0.041096
0.017613
0.011742
0.023483
0.050881
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0.031311
0.054795
0.017613
0.019569
0.023483
0.035225
0.019569
0.039139
0.04501
0
35,151
T
T
G
A
A
A
G
A
A
T
T
A
T
T
T
C
C
A
G
T
A
T
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C
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A
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C
T
T
G
A
A
A
A
T
T
T
A
T
G
A
A
A
G
A
C
A
0.091977
0.019569
0.066536
0.072407
0.050881
0.009785
0
0.027397
0.04501
0.02544
0.023483
0.043053
0.019569
0.060665
0.046967
0.033268
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0
0.017613
0.023483
0.054795
0.013699
0.027397
0.02544
0.015656
0.023483
0.056751
0.050881
0
35,152
G
T
T
T
A
G
T
A
A
G
G
C
T
C
G
A
A
A
A
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T
T
T
C
T
C
T
A
0.060665
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0.07045
0.048924
0.058708
0.023483
0
0.035225
0.048924
0.027397
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0
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0.019569
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0.019569
0.041096
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0
35,153
T
G
C
A
G
G
G
T
T
T
C
T
C
T
C
C
A
G
T
A
T
G
A
A
T
T
C
T
C
T
T
A
T
A
A
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T
A
A
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G
C
T
G
A
G
G
A
C
C
A
G
T
T
A
A
A
G
G
C
T
T
T
G
C
0.076321
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0
0.033268
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0
0
0.017613
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0.058708
0.011742
0.035225
0.027397
0.015656
0.031311
0.050881
0.04501
0
35,154
C
T
T
T
A
C
C
A
C
A
T
T
C
T
T
T
A
T
A
T
T
T
G
T
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G
G
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T
T
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C
C
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T
C
C
A
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T
A
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G
T
T
A
T
C
T
T
A
T
G
T
C
T
A
T
T
A
A
G
G
T
0.086106
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0
35,155
A
C
T
G
T
A
A
A
T
T
G
T
G
A
T
G
T
C
C
A
C
A
T
T
T
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C
A
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T
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T
C
T
C
A
G
T
A
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A
T
T
C
T
T
T
G
C
A
A
A
G
A
A
G
C
T
T
T
T
G
0.101761
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0
0.023483
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0.021526
0.013699
0.033268
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0.041096
0
35,156
G
A
A
A
A
T
T
C
A
T
A
C
T
A
T
C
A
C
A
C
C
T
G
T
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T
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G
G
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C
C
G
A
G
G
C
G
G
G
C
G
G
A
T
C
A
C
G
A
G
C
0.068493
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0.046967
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0.019569
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0.033268
0
35,157
A
G
A
A
A
A
T
T
C
A
T
A
C
T
A
T
C
A
C
A
C
C
T
G
T
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G
G
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C
C
G
A
G
G
C
G
G
G
C
G
G
A
T
C
A
C
G
A
G
0.066536
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0.023483
0.046967
0.031311
0.019569
0.035225
0.033268
0
35,158
T
C
T
G
G
T
A
T
G
A
A
T
T
C
T
C
T
T
A
T
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T
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A
A
A
T
G
C
T
T
T
G
T
C
A
C
A
T
T
C
T
T
C
0.068493
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0
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0
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0.050881
0.037182
0
35,159
A
T
G
T
T
T
A
G
T
A
A
G
G
G
T
T
G
A
G
A
G
T
C
G
C
T
T
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A
A
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C
T
T
T
G
T
C
A
C
A
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T
C
T
T
T
A
C
A
T
T
T
G
T
A
G
G
G
T
T
T
C
T
T
0.084149
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0
35,160
A
A
G
A
T
T
C
T
T
T
T
C
A
A
A
A
A
G
T
A
T
T
A
C
T
G
A
G
A
A
A
A
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A
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T
G
G
A
C
A
T
G
A
G
A
A
T
T
T
A
C
A
G
T
T
A
C
0.152642
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0
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0.011742
0.019569
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0.052838
0.037182
0
35,161
A
T
T
C
T
C
T
C
C
G
G
A
G
G
A
G
T
G
G
C
A
A
T
G
T
C
T
G
G
A
C
A
C
T
G
C
A
C
A
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C
A
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A
A
T
T
T
A
T
A
T
A
G
G
A
A
T
G
T
G
A
T
G
T
T
0.101761
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0.023483
0.02544
0.029354
0.017613
0.041096
0.033268
0
35,162
C
C
T
A
A
C
T
C
G
A
C
A
T
G
A
A
A
G
A
A
A
T
T
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C
A
A
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G
T
G
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A
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C
T
G
C
A
A
A
T
G
T
G
A
A
G
A
A
T
G
T
G
A
A
A
A
A
G
C
0.099804
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0.064579
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0
0.027397
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0
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0
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0.054795
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0.02544
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0.011742
0.02544
0.068493
0.043053
0
35,163
G
C
T
G
C
A
A
G
G
A
A
C
T
T
A
A
G
G
A
C
A
T
C
C
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C
C
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C
C
T
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C
A
T
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T
G
C
A
G
G
A
C
A
T
C
A
A
G
G
G
C
T
C
C
G
G
A
C
A
T
T
G
T
A
0.050881
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0.027397
0.050881
0.019569
0.031311
0.031311
0
35,164
G
G
T
C
A
G
C
C
C
T
G
G
G
G
T
C
A
G
T
A
A
C
C
A
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A
A
G
A
A
G
C
C
G
T
G
G
C
T
C
C
C
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G
A
A
G
G
C
T
G
C
C
T
G
G
A
T
C
T
G
G
T
T
A
T
0.019569
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0.046967
0.041096
0.041096
0.017613
0.017613
0.035225
0
35,165
A
G
A
T
T
T
G
A
A
G
A
T
C
G
A
T
T
A
A
A
A
C
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G
C
C
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C
A
T
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A
C
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T
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G
T
A
G
A
G
T
T
T
C
T
C
T
C
C
A
A
C
A
T
G
A
0.056751
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0.031311
0.015656
0.021526
0.031311
0.050881
0.029354
0
35,166
G
G
C
G
G
G
A
G
G
G
C
T
C
C
C
G
G
G
C
G
G
C
G
G
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C
T
C
T
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G
T
C
G
C
C
G
C
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C
G
G
G
C
T
C
G
G
A
G
G
T
G
G
T
A
C
G
G
C
T
C
G
G
0
0.007828
0.007828
0
0.027397
0.011742
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0
0.017613
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0.033268
0.048924
0.11546
0.035225
0.011742
0.001957
0.001957
0
35,167
C
C
C
C
T
C
G
C
C
C
C
C
T
T
C
G
G
C
C
C
C
G
G
C
C
C
C
T
G
C
C
C
T
G
G
T
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C
C
G
T
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C
G
C
G
C
C
C
C
G
G
A
T
G
T
G
G
C
G
C
G
G
C
C
0.013699
0.019569
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0
0.019569
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0.048924
0.119374
0.029354
0.001957
0.003914
0.017613
0
35,168
G
T
G
C
A
G
C
G
G
G
A
A
C
G
C
G
G
C
G
C
C
C
A
G
C
T
C
C
A
G
C
G
C
G
C
G
T
C
G
C
A
T
G
T
C
C
G
C
T
T
C
C
A
G
C
A
G
G
T
C
C
A
G
G
C
A
0.003914
0.011742
0.017613
0
0.015656
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0.009785
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0
0.007828
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0.017613
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0.037182
0.001957
0
0.015656
0
35,169
C
A
G
C
G
G
C
G
A
C
G
A
G
T
C
A
A
T
G
G
T
T
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A
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C
A
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C
T
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T
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C
C
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G
A
G
C
A
C
T
A
C
C
A
C
G
G
G
C
G
G
C
T
C
0.103718
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0.056751
0.054795
0.027397
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0.013699
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0.035225
0.027397
0.015656
0.017613
0.046967
0.039139
0
35,170
C
T
G
C
G
T
C
C
C
A
C
T
C
T
T
G
G
C
C
A
T
C
A
C
C
G
A
T
G
C
C
A
C
G
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A
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C
A
C
T
T
C
A
G
T
T
T
C
C
C
T
G
C
C
T
C
A
C
T
0.080235
0.021526
0.041096
0.035225
0.031311
0.021526
0.015656
0.041096
0.043053
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0.027397
0.043053
0.007828
0.023483
0.043053
0
35,171
C
A
G
A
A
C
T
C
C
T
G
C
G
G
T
G
A
A
C
T
C
G
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C
A
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C
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C
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C
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C
C
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C
G
T
C
C
G
C
T
C
G
C
T
C
C
A
A
G
T
A
G
C
T
0.043053
0.023483
0.050881
0.027397
0.029354
0.029354
0.011742
0.029354
0.054795
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0.048924
0.023483
0.041096
0.02544
0.043053
0.013699
0.021526
0.033268
0
35,172
T
G
C
T
T
G
C
C
T
G
C
A
G
A
G
C
C
C
C
C
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C
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G
G
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C
T
G
A
G
T
C
C
A
A
G
A
C
G
A
T
0.04501
0.033268
0.043053
0.021526
0.035225
0.02544
0.017613
0.033268
0.050881
0.031311
0.043053
0.013699
0.02544
0.037182
0.031311
0.031311
0.058708
0.041096
0.037182
0.009785
0.005871
0.005871
0.021526
0.035225
0.035225
0.031311
0.043053
0.037182
0.031311
0.015656
0.031311
0.041096
0
35,173
A
G
C
T
G
C
G
G
G
G
C
A
A
C
A
T
A
A
G
G
A
A
A
G
A
T
G
A
C
T
G
C
C
A
A
T
G
T
G
T
G
A
T
T
A
G
A
A
A
C
G
A
T
G
A
A
C
C
T
G
T
A
A
T
C
A
0.076321
0.023483
0.050881
0.033268
0.037182
0.029354
0.013699
0.035225
0.048924
0.02544
0.033268
0.037182
0.027397
0.031311
0.02544
0.039139
0.043053
0.037182
0.035225
0.003914
0.005871
0.015656
0.017613
0.031311
0.035225
0.031311
0.019569
0.021526
0.023483
0.021526
0.04501
0.04501
0
35,174
A
G
G
G
C
G
C
C
C
A
G
C
T
G
T
C
T
G
T
G
G
G
A
G
C
C
A
T
C
A
G
C
C
T
G
G
C
G
T
T
T
T
A
C
A
A
T
G
G
A
C
T
C
T
G
G
G
C
C
T
A
T
G
A
T
A
0.039139
0.027397
0.029354
0.023483
0.04501
0.033268
0.009785
0.02544
0.041096
0.029354
0.046967
0.009785
0.027397
0.037182
0.023483
0.048924
0.054795
0.054795
0.060665
0.013699
0.011742
0.011742
0.005871
0.050881
0.037182
0.029354
0.019569
0.033268
0.046967
0.007828
0.019569
0.04501
0
35,175
C
T
T
C
T
C
C
G
A
G
T
A
T
G
T
G
T
G
T
G
C
G
C
C
C
T
T
C
T
A
T
G
T
G
G
G
C
T
G
C
A
A
G
C
C
T
C
C
T
C
A
A
A
T
C
G
T
T
G
T
G
A
A
A
T
C
0.011742
0.003914
0.027397
0.007828
0.033268
0.02544
0.011742
0.019569
0.031311
0.037182
0.076321
0.005871
0.023483
0.021526
0.017613
0.048924
0.076321
0.050881
0.091977
0.023483
0.007828
0.019569
0.007828
0.052838
0.017613
0.019569
0.04501
0.09002
0.037182
0.017613
0.003914
0.035225
0