Datasets:
TabBioMed
/
vep_pathogenic_coding

Dataset card Data Studio Files
xet
 Community
row_idx
int64
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f_66_k3_w513_AAA
float64
f_67_k3_w513_AAC
float64
f_68_k3_w513_AAG
float64
f_69_k3_w513_AAT
float64
f_70_k3_w513_ACA
float64
f_71_k3_w513_ACC
float64
f_72_k3_w513_ACG
float64
f_73_k3_w513_ACT
float64
f_74_k3_w513_AGA
float64
f_75_k3_w513_AGC
float64
f_76_k3_w513_AGG
float64
f_77_k3_w513_ATA
float64
f_78_k3_w513_ATC
float64
f_79_k3_w513_ATG
float64
f_80_k3_w513_CAA
float64
f_81_k3_w513_CAC
float64
f_82_k3_w513_CAG
float64
f_83_k3_w513_CCA
float64
f_84_k3_w513_CCC
float64
f_85_k3_w513_CCG
float64
f_86_k3_w513_CGA
float64
f_87_k3_w513_CGC
float64
f_88_k3_w513_CTA
float64
f_89_k3_w513_CTC
float64
f_90_k3_w513_GAA
float64
f_91_k3_w513_GAC
float64
f_92_k3_w513_GCA
float64
f_93_k3_w513_GCC
float64
f_94_k3_w513_GGA
float64
f_95_k3_w513_GTA
float64
f_96_k3_w513_TAA
float64
f_97_k3_w513_TCA
float64
target
int64
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0.041096
0.041096
0.037182
0.021526
0.035225
0.037182
0.029354
0.039139
0.043053
0.037182
0.029354
0.011742
0.005871
0.011742
0.019569
0.033268
0.04501
0.021526
0.021526
0.019569
0.041096
0.019569
0.02544
0.046967
1
4,864
C
C
A
G
G
T
G
T
G
A
T
G
A
T
T
A
C
T
T
C
T
T
T
A
T
A
G
C
C
C
A
T
C
G
T
G
G
A
G
A
A
C
G
G
C
G
G
G
G
C
A
T
T
G
G
T
G
G
T
A
T
C
T
T
T
T
0.093933
0.019569
0.050881
0.031311
0.039139
0.023483
0.009785
0.02544
0.043053
0.039139
0.037182
0.021526
0.035225
0.037182
0.027397
0.037182
0.043053
0.037182
0.027397
0.009785
0.005871
0.009785
0.019569
0.033268
0.046967
0.021526
0.021526
0.019569
0.041096
0.019569
0.02544
0.046967
1
4,865
A
G
A
T
A
C
C
A
C
C
A
A
T
G
C
C
C
C
G
C
C
G
T
T
C
T
C
C
A
C
G
A
T
G
G
G
C
T
A
T
A
A
A
G
A
A
G
T
A
A
T
C
A
T
C
A
C
A
C
C
T
G
G
A
A
C
0.097847
0.019569
0.050881
0.031311
0.039139
0.023483
0.009785
0.02544
0.043053
0.039139
0.037182
0.019569
0.035225
0.037182
0.027397
0.037182
0.043053
0.037182
0.027397
0.009785
0.005871
0.009785
0.017613
0.033268
0.046967
0.021526
0.021526
0.019569
0.041096
0.019569
0.02544
0.046967
1
4,866
C
T
C
C
A
A
C
A
T
A
C
T
T
G
A
A
T
C
A
A
G
A
A
G
A
C
G
C
T
G
T
C
C
A
T
T
T
T
C
A
C
A
G
A
A
C
T
C
T
G
A
A
G
G
A
G
G
C
T
T
G
T
G
A
C
G
0.101761
0.02544
0.048924
0.068493
0.027397
0.033268
0.001957
0.039139
0.04501
0.029354
0.02544
0.029354
0.019569
0.039139
0.031311
0.023483
0.039139
0.043053
0.011742
0.001957
0
0.003914
0.031311
0.019569
0.046967
0.023483
0.019569
0.013699
0.021526
0.029354
0.062622
0.043053
1
4,867
A
T
T
C
A
A
G
T
A
T
G
T
T
G
G
A
G
T
G
A
G
G
T
C
A
C
A
T
C
C
A
C
C
A
C
C
A
A
A
C
C
A
C
C
A
C
T
G
C
T
T
G
T
T
G
C
C
T
A
C
C
A
A
A
T
G
0.091977
0.021526
0.046967
0.056751
0.027397
0.031311
0.001957
0.035225
0.041096
0.033268
0.033268
0.019569
0.021526
0.043053
0.031311
0.02544
0.043053
0.048924
0.017613
0.001957
0.001957
0.005871
0.029354
0.02544
0.043053
0.023483
0.023483
0.027397
0.02544
0.02544
0.050881
0.04501
1
4,868
G
T
G
T
G
T
T
T
T
C
G
A
A
A
A
G
G
C
T
G
G
G
G
T
G
A
G
C
A
T
T
T
C
T
G
T
T
G
T
T
C
A
T
G
G
A
A
A
T
C
T
T
T
C
A
G
A
G
G
A
A
G
C
T
G
T
0.121331
0.029354
0.050881
0.056751
0.04501
0.013699
0.005871
0.029354
0.041096
0.035225
0.015656
0.062622
0.021526
0.043053
0.041096
0.023483
0.031311
0.019569
0.017613
0.007828
0.005871
0.003914
0.019569
0.017613
0.043053
0.015656
0.037182
0.013699
0.015656
0.02544
0.052838
0.037182
1
4,869
A
T
G
A
A
C
A
A
C
A
G
A
A
A
T
G
C
T
C
A
C
C
C
C
A
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C
C
T
T
T
T
C
G
A
A
A
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A
C
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C
C
C
A
T
C
T
T
G
A
A
G
T
A
C
A
C
A
G
C
T
G
A
T
0.111546
0.031311
0.048924
0.052838
0.043053
0.015656
0.005871
0.031311
0.04501
0.029354
0.017613
0.066536
0.023483
0.04501
0.037182
0.02544
0.029354
0.019569
0.017613
0.007828
0.005871
0.003914
0.02544
0.019569
0.04501
0.015656
0.035225
0.013699
0.015656
0.02544
0.050881
0.039139
1
4,870
T
A
A
T
C
A
T
C
A
A
A
G
C
T
C
A
A
C
T
T
G
G
G
G
A
G
G
A
T
A
T
T
C
G
G
C
G
A
A
T
T
C
C
T
A
T
T
C
A
T
A
A
T
G
A
A
G
A
T
A
T
T
A
C
T
T
0.101761
0.041096
0.04501
0.039139
0.031311
0.015656
0.005871
0.04501
0.041096
0.035225
0.021526
0.050881
0.035225
0.04501
0.035225
0.019569
0.02544
0.031311
0.013699
0.005871
0.005871
0.001957
0.031311
0.041096
0.033268
0.013699
0.015656
0.013699
0.029354
0.023483
0.058708
0.046967
1
4,871
G
A
C
C
C
C
T
T
G
A
A
T
C
A
A
G
T
C
A
G
G
T
G
A
A
A
T
A
T
C
T
C
C
G
T
C
G
A
G
A
A
C
T
G
A
T
A
G
A
A
C
T
T
C
G
A
A
A
T
A
A
A
G
T
G
T
0.127202
0.039139
0.052838
0.068493
0.02544
0.019569
0.007828
0.037182
0.046967
0.011742
0.029354
0.054795
0.023483
0.027397
0.039139
0.011742
0.02544
0.035225
0.009785
0.001957
0.009785
0
0.021526
0.023483
0.058708
0.017613
0.011742
0.011742
0.035225
0.021526
0.062622
0.031311
1
4,872
C
T
T
T
C
A
A
C
A
C
C
T
G
C
T
C
A
C
C
T
G
A
A
T
A
C
T
G
A
A
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A
C
C
A
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A
C
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T
T
G
A
G
G
C
T
G
C
T
G
A
G
G
T
G
G
A
G
C
C
T
G
C
A
0.093933
0.046967
0.033268
0.058708
0.068493
0.023483
0
0.035225
0.035225
0.017613
0.027397
0.060665
0.017613
0.041096
0.041096
0.029354
0.039139
0.02544
0.011742
0.005871
0
0.001957
0.017613
0.02544
0.041096
0.003914
0.021526
0.017613
0.017613
0.046967
0.058708
0.035225
1
4,873
T
A
A
A
G
T
C
A
A
A
A
T
C
T
G
T
A
A
C
T
A
C
A
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A
T
A
C
C
T
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C
A
A
A
T
G
G
C
C
C
C
G
T
G
C
C
C
A
G
G
C
A
T
A
A
T
G
T
C
A
C
A
C
A
0.07045
0.033268
0.035225
0.048924
0.04501
0.017613
0.003914
0.035225
0.043053
0.017613
0.048924
0.046967
0.021526
0.039139
0.033268
0.027397
0.050881
0.02544
0.02544
0.003914
0
0
0.037182
0.021526
0.041096
0.021526
0.041096
0.037182
0.023483
0.021526
0.043053
0.039139
1
4,874
T
T
C
T
A
T
G
T
T
C
C
A
C
A
G
A
T
T
C
A
C
T
A
A
A
A
T
T
T
G
T
G
C
C
C
A
T
T
T
C
A
A
A
T
A
T
A
C
T
T
G
T
G
A
C
T
C
C
A
T
C
C
T
C
A
T
0.062622
0.013699
0.048924
0.058708
0.054795
0.007828
0.003914
0.033268
0.035225
0.035225
0.048924
0.041096
0.029354
0.035225
0.033268
0.035225
0.037182
0.027397
0.021526
0
0.005871
0.001957
0.039139
0.027397
0.048924
0.021526
0.015656
0.02544
0.043053
0.027397
0.037182
0.043053
1
4,875
A
A
A
T
A
A
A
T
C
T
A
C
A
T
G
A
G
A
C
T
T
T
T
C
T
G
T
T
G
A
T
G
T
T
A
A
A
A
G
C
A
A
T
T
T
G
T
C
C
C
A
T
T
T
T
T
C
T
T
G
A
T
A
C
C
C
0.09589
0.039139
0.041096
0.060665
0.037182
0.017613
0.007828
0.02544
0.043053
0.019569
0.02544
0.043053
0.033268
0.052838
0.050881
0.011742
0.037182
0.043053
0.017613
0.003914
0.003914
0
0.023483
0.011742
0.04501
0.017613
0.041096
0.02544
0.029354
0.019569
0.04501
0.031311
1
4,876
T
A
A
A
A
C
G
C
C
A
T
G
T
C
A
G
A
A
C
A
C
A
T
A
C
T
G
G
T
G
A
A
C
G
G
C
C
C
T
A
T
G
T
C
T
G
T
C
C
T
G
T
A
T
G
T
A
G
C
G
A
A
G
C
C
T
0.086106
0.033268
0.054795
0.021526
0.048924
0.015656
0.005871
0.04501
0.041096
0.039139
0.033268
0.035225
0.015656
0.048924
0.02544
0.035225
0.039139
0.033268
0.007828
0.005871
0.007828
0.003914
0.035225
0.027397
0.039139
0.021526
0.041096
0.02544
0.031311
0.02544
0.04501
0.02544
1
4,877
A
G
A
T
C
G
G
G
C
A
T
C
A
G
C
C
C
A
A
G
C
T
A
C
T
C
C
A
C
A
T
G
T
T
A
A
G
C
A
C
T
C
A
A
A
T
G
G
C
T
T
A
A
C
T
C
C
T
A
A
A
A
A
A
A
C
0.086106
0.029354
0.050881
0.023483
0.048924
0.019569
0.007828
0.037182
0.031311
0.037182
0.037182
0.033268
0.021526
0.046967
0.02544
0.043053
0.037182
0.035225
0.013699
0.011742
0.007828
0.003914
0.031311
0.023483
0.031311
0.015656
0.046967
0.037182
0.029354
0.02544
0.046967
0.023483
1
4,878
C
T
A
A
G
A
G
A
G
T
A
T
A
G
G
A
G
A
C
A
C
A
T
G
A
A
C
A
A
C
C
A
T
G
A
A
G
G
T
A
A
C
T
A
T
A
C
T
T
T
A
T
A
T
T
A
T
A
T
G
T
A
T
C
C
G
0.084149
0.029354
0.060665
0.058708
0.041096
0.027397
0.005871
0.029354
0.039139
0.031311
0.037182
0.068493
0.017613
0.033268
0.031311
0.031311
0.027397
0.027397
0.013699
0.001957
0
0
0.027397
0.021526
0.062622
0.009785
0.013699
0.009785
0.029354
0.033268
0.054795
0.041096
1
4,879
C
C
A
A
A
C
G
G
A
G
T
C
T
T
C
A
A
G
A
A
C
A
T
A
T
G
A
G
T
A
T
T
C
A
C
A
C
A
G
G
T
A
A
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G
A
G
A
A
A
T
T
T
A
T
A
T
T
G
A
C
A
T
A
G
T
0.076321
0.029354
0.029354
0.082192
0.046967
0.019569
0.007828
0.031311
0.043053
0.015656
0.023483
0.064579
0.029354
0.035225
0.029354
0.035225
0.041096
0.021526
0.013699
0.007828
0.003914
0.007828
0.015656
0.027397
0.035225
0.02544
0.017613
0.017613
0.015656
0.019569
0.076321
0.054795
1
4,880
C
T
C
T
T
C
C
A
T
T
A
G
C
T
T
A
T
G
T
A
C
A
C
T
T
T
C
A
C
A
A
A
T
C
T
C
T
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A
G
A
C
T
T
C
T
G
A
C
A
T
G
A
A
A
A
G
A
T
G
A
C
G
A
G
A
0.054795
0.02544
0.050881
0.052838
0.050881
0.021526
0.005871
0.037182
0.039139
0.039139
0.037182
0.039139
0.019569
0.037182
0.04501
0.013699
0.050881
0.033268
0.015656
0
0.007828
0.001957
0.027397
0.023483
0.048924
0.019569
0.02544
0.019569
0.029354
0.054795
0.035225
0.037182
1
4,881
T
G
G
T
G
C
G
C
G
G
C
G
G
G
A
C
T
C
T
G
T
A
T
T
A
C
C
A
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C
G
G
C
G
G
C
A
G
C
G
G
C
A
C
C
G
C
A
A
G
A
C
C
T
T
C
G
C
G
G
A
G
C
T
G
T
0.015656
0.007828
0.017613
0.005871
0.013699
0.046967
0.031311
0.013699
0.013699
0.046967
0.056751
0.005871
0.009785
0.013699
0.015656
0.033268
0.04501
0.029354
0.043053
0.078278
0.039139
0.086106
0.017613
0.050881
0.011742
0.035225
0.04501
0.080235
0.035225
0.029354
0.005871
0.019569
1
4,882
T
T
T
G
A
T
C
C
A
A
G
A
G
A
T
G
A
A
G
G
C
T
C
C
A
G
G
T
G
T
T
G
C
A
G
C
A
T
C
A
T
T
G
A
C
C
C
C
T
T
T
G
G
C
A
T
G
C
C
G
A
T
G
C
T
G
0.076321
0.031311
0.035225
0.031311
0.033268
0.033268
0.017613
0.031311
0.027397
0.015656
0.041096
0.029354
0.043053
0.056751
0.039139
0.029354
0.021526
0.035225
0.035225
0.011742
0.019569
0.001957
0.033268
0.02544
0.033268
0.031311
0.02544
0.023483
0.031311
0.021526
0.02544
0.052838
1
4,883
C
A
T
C
A
T
A
T
G
T
G
A
G
A
A
A
T
G
C
C
A
T
G
T
A
A
C
C
T
G
G
A
T
G
T
G
T
C
A
C
A
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C
T
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A
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A
A
A
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T
C
C
A
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T
C
C
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C
A
A
A
A
0.09589
0.033268
0.048924
0.064579
0.041096
0.027397
0.005871
0.02544
0.04501
0.027397
0.019569
0.064579
0.031311
0.04501
0.035225
0.019569
0.02544
0.029354
0.015656
0.007828
0.001957
0.003914
0.029354
0.013699
0.035225
0.017613
0.023483
0.011742
0.017613
0.029354
0.076321
0.031311
1
4,884
A
G
A
A
A
T
C
C
C
T
G
T
G
A
T
T
G
T
G
G
A
A
A
A
T
A
A
C
T
C
C
A
C
G
G
A
T
G
T
C
T
T
G
G
T
A
G
A
G
G
T
G
A
G
T
C
A
C
A
T
A
A
A
A
G
T
0.074364
0.027397
0.039139
0.066536
0.058708
0.019569
0.001957
0.039139
0.035225
0.019569
0.035225
0.052838
0.017613
0.039139
0.029354
0.048924
0.031311
0.033268
0.015656
0.001957
0
0
0.039139
0.017613
0.039139
0.017613
0.02544
0.02544
0.02544
0.02544
0.066536
0.031311
1
4,885
G
T
T
T
T
G
C
A
G
C
A
G
C
A
G
T
C
C
A
A
C
A
A
G
C
G
G
A
G
C
A
A
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A
A
C
T
T
G
C
A
G
G
C
T
C
C
C
A
A
A
A
C
C
T
T
C
A
T
C
A
A
C
A
C
G
0.135029
0.041096
0.056751
0.039139
0.041096
0.017613
0.003914
0.037182
0.029354
0.031311
0.037182
0.041096
0.021526
0.023483
0.058708
0.019569
0.043053
0.031311
0.011742
0.001957
0
0.001957
0.013699
0.021526
0.041096
0.011742
0.039139
0.021526
0.031311
0.027397
0.035225
0.033268
1
4,886
T
C
T
T
C
T
T
C
T
T
T
C
A
G
G
T
T
G
A
G
C
A
A
T
G
T
T
T
A
A
A
G
C
G
T
T
T
G
A
A
A
A
A
C
A
T
G
A
A
T
T
T
G
G
A
G
G
G
C
T
C
A
A
T
T
T
0.09002
0.031311
0.04501
0.068493
0.046967
0.031311
0.001957
0.027397
0.041096
0.031311
0.023483
0.037182
0.02544
0.033268
0.058708
0.031311
0.037182
0.041096
0.017613
0
0
0.005871
0.017613
0.023483
0.046967
0.019569
0.023483
0.005871
0.027397
0.02544
0.037182
0.046967
1
4,887
T
G
C
T
T
T
A
G
C
T
T
A
T
G
A
A
C
G
T
G
A
T
G
G
G
G
A
A
A
T
T
C
T
A
G
C
C
A
C
A
G
G
G
G
T
A
A
G
C
A
G
T
A
C
A
T
T
T
C
C
T
T
T
C
T
A
0.09589
0.031311
0.056751
0.078278
0.033268
0.011742
0.009785
0.037182
0.039139
0.029354
0.023483
0.046967
0.023483
0.031311
0.043053
0.021526
0.027397
0.017613
0.019569
0.003914
0.005871
0.003914
0.023483
0.019569
0.068493
0.013699
0.019569
0.005871
0.027397
0.02544
0.052838
0.052838
1
4,888
C
A
G
T
G
C
G
A
A
G
T
A
C
A
G
G
A
T
C
T
C
C
A
A
C
A
G
A
C
A
C
A
C
C
A
G
C
T
A
A
A
A
A
C
A
G
C
A
G
C
T
A
A
G
G
A
A
A
A
C
C
T
A
C
T
T
0.072407
0.048924
0.04501
0.031311
0.054795
0.029354
0.011742
0.039139
0.046967
0.023483
0.031311
0.048924
0.023483
0.027397
0.037182
0.027397
0.048924
0.031311
0.019569
0.005871
0.003914
0.001957
0.02544
0.023483
0.041096
0.027397
0.023483
0.005871
0.033268
0.031311
0.046967
0.031311
1
4,889
G
C
T
G
A
T
A
T
C
C
G
A
C
A
A
A
G
G
T
C
T
T
T
G
A
A
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A
C
C
A
T
C
A
A
A
A
A
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G
G
C
T
C
C
C
A
T
A
A
T
G
C
C
A
G
G
A
C
C
A
A
G
C
T
A
0.088063
0.043053
0.048924
0.035225
0.048924
0.027397
0.007828
0.046967
0.048924
0.023483
0.027397
0.033268
0.021526
0.027397
0.033268
0.02544
0.046967
0.033268
0.019569
0.005871
0.003914
0.001957
0.029354
0.023483
0.046967
0.02544
0.019569
0.005871
0.033268
0.037182
0.048924
0.031311
1
4,890
G
T
A
T
A
A
A
T
A
G
A
G
G
C
T
T
C
T
C
T
A
G
C
A
G
C
A
A
C
A
G
G
C
A
T
A
T
T
G
G
A
G
G
T
A
T
T
G
G
C
T
A
C
C
A
A
A
G
C
T
G
T
C
C
T
T
0.09002
0.019569
0.048924
0.052838
0.02544
0.029354
0.003914
0.033268
0.046967
0.039139
0.037182
0.060665
0.013699
0.02544
0.031311
0.029354
0.027397
0.039139
0.017613
0.009785
0
0.001957
0.037182
0.043053
0.033268
0.009785
0.021526
0.027397
0.027397
0.033268
0.056751
0.027397
1
4,891
G
G
A
C
A
G
C
T
T
T
G
G
T
A
G
C
C
A
A
T
A
C
C
T
C
C
A
A
T
A
T
G
C
C
T
G
T
T
G
C
T
G
C
T
A
G
A
G
A
A
G
C
C
T
C
T
A
T
T
T
A
T
A
C
T
T
0.09002
0.019569
0.048924
0.052838
0.02544
0.029354
0.003914
0.033268
0.04501
0.039139
0.037182
0.060665
0.013699
0.02544
0.031311
0.029354
0.027397
0.039139
0.017613
0.009785
0
0.001957
0.037182
0.043053
0.033268
0.009785
0.021526
0.027397
0.029354
0.033268
0.056751
0.027397
1
4,892
T
C
T
A
A
G
G
G
C
C
T
C
A
G
C
C
C
A
T
C
T
A
G
A
G
G
T
A
G
A
G
T
C
A
G
C
C
A
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C
A
T
A
C
T
G
A
C
A
T
G
A
T
A
G
C
C
C
A
T
G
T
C
A
C
T
0.076321
0.023483
0.043053
0.039139
0.037182
0.013699
0.013699
0.029354
0.050881
0.037182
0.037182
0.039139
0.031311
0.039139
0.019569
0.029354
0.048924
0.033268
0.02544
0.005871
0.007828
0
0.035225
0.027397
0.043053
0.019569
0.031311
0.033268
0.027397
0.023483
0.043053
0.035225
1
4,893
T
C
A
G
C
T
A
A
A
C
G
A
C
C
A
G
A
G
A
T
T
T
C
T
C
T
A
A
G
G
G
C
C
T
C
A
G
C
C
C
A
T
C
T
A
G
A
G
G
T
A
G
A
G
T
C
A
G
C
C
A
T
C
A
T
A
0.076321
0.021526
0.041096
0.041096
0.039139
0.013699
0.015656
0.029354
0.048924
0.041096
0.039139
0.035225
0.029354
0.035225
0.021526
0.027397
0.050881
0.029354
0.02544
0.005871
0.007828
0.001957
0.035225
0.031311
0.043053
0.021526
0.029354
0.029354
0.031311
0.02544
0.039139
0.037182
1
4,894
C
A
G
A
C
T
T
A
C
C
T
G
C
A
G
G
C
A
T
T
T
C
A
G
C
T
A
A
A
C
G
A
C
C
A
G
A
G
A
T
T
T
C
T
C
T
A
A
G
G
G
C
C
T
C
A
G
C
C
C
A
T
C
T
A
A
0.076321
0.019569
0.04501
0.039139
0.037182
0.015656
0.015656
0.033268
0.048924
0.041096
0.035225
0.037182
0.027397
0.033268
0.019569
0.033268
0.048924
0.031311
0.027397
0.005871
0.007828
0.001957
0.033268
0.031311
0.039139
0.021526
0.029354
0.029354
0.027397
0.027397
0.043053
0.037182
1
4,895
G
A
C
G
G
G
C
A
C
C
A
A
G
A
T
A
G
G
C
T
G
G
A
T
A
T
C
C
A
C
T
A
T
C
T
G
A
A
A
A
A
T
G
A
A
A
A
G
A
A
A
T
T
T
T
A
A
A
A
C
A
G
A
G
T
C
0.080235
0.017613
0.04501
0.043053
0.031311
0.015656
0.011742
0.035225
0.056751
0.037182
0.031311
0.037182
0.027397
0.033268
0.019569
0.027397
0.046967
0.029354
0.027397
0.009785
0.007828
0.005871
0.027397
0.041096
0.039139
0.023483
0.029354
0.02544
0.029354
0.023483
0.046967
0.037182
1
4,896
G
T
T
T
T
T
G
T
G
T
G
T
G
T
G
T
T
T
T
T
T
T
T
A
A
T
C
A
G
G
T
G
T
T
C
T
G
G
G
G
C
T
T
A
G
A
T
A
A
G
A
A
A
C
T
A
G
C
T
C
A
A
C
G
T
A
0.084149
0.039139
0.037182
0.037182
0.054795
0.021526
0.009785
0.029354
0.041096
0.041096
0.031311
0.017613
0.021526
0.033268
0.04501
0.037182
0.048924
0.035225
0.02544
0.003914
0.007828
0.005871
0.019569
0.037182
0.04501
0.015656
0.031311
0.023483
0.027397
0.023483
0.02544
0.043053
1
4,897
C
G
T
A
G
G
A
C
T
T
C
T
C
T
C
C
C
C
G
G
T
G
G
A
G
G
C
G
C
A
T
G
T
G
C
A
C
G
T
T
G
A
G
G
G
A
G
C
T
C
T
T
C
T
G
G
G
T
G
A
A
G
C
G
C
C
0.037182
0.021526
0.041096
0.013699
0.048924
0.029354
0.021526
0.019569
0.04501
0.037182
0.048924
0.011742
0.017613
0.031311
0.039139
0.052838
0.050881
0.039139
0.052838
0.009785
0.011742
0.023483
0.011742
0.046967
0.02544
0.029354
0.062622
0.029354
0.039139
0.015656
0.011742
0.023483
1
4,898
A
T
A
C
C
A
G
T
G
T
A
G
T
A
T
C
T
G
C
A
A
C
A
A
G
C
G
C
T
T
C
A
C
C
C
A
G
A
A
G
A
G
C
T
C
C
C
T
C
A
A
C
G
T
G
C
A
C
A
T
G
C
G
C
C
T
0.050881
0.017613
0.043053
0.023483
0.046967
0.027397
0.019569
0.017613
0.04501
0.039139
0.046967
0.013699
0.017613
0.023483
0.041096
0.050881
0.050881
0.037182
0.052838
0.009785
0.009785
0.023483
0.011742
0.04501
0.023483
0.027397
0.060665
0.029354
0.037182
0.015656
0.019569
0.021526
1
4,899
T
G
A
G
G
G
A
G
C
T
C
T
T
C
T
G
G
G
T
G
A
A
G
C
G
C
T
T
G
T
T
G
C
A
G
A
T
A
C
T
A
C
A
C
T
G
G
T
A
T
G
C
C
C
T
C
A
C
T
C
C
T
G
T
G
A
0.048924
0.017613
0.043053
0.023483
0.046967
0.02544
0.021526
0.017613
0.04501
0.037182
0.048924
0.013699
0.021526
0.027397
0.037182
0.050881
0.048924
0.037182
0.052838
0.009785
0.007828
0.023483
0.011742
0.04501
0.023483
0.02544
0.058708
0.029354
0.041096
0.015656
0.021526
0.021526
1
4,900
T
G
A
G
G
G
A
G
C
T
C
T
T
C
T
G
G
G
T
G
A
A
G
C
G
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T
G
T
T
G
C
A
G
A
T
A
C
T
A
C
A
C
T
G
G
T
A
T
G
C
C
C
T
C
A
C
T
C
C
T
G
T
G
T
0.048924
0.017613
0.043053
0.023483
0.046967
0.02544
0.021526
0.017613
0.04501
0.037182
0.048924
0.013699
0.021526
0.027397
0.037182
0.050881
0.048924
0.037182
0.052838
0.009785
0.007828
0.023483
0.011742
0.04501
0.023483
0.02544
0.058708
0.029354
0.041096
0.015656
0.021526
0.021526
1
4,901
T
G
G
T
G
A
C
A
C
A
C
A
C
A
G
G
A
G
T
G
A
G
G
G
C
A
T
A
C
C
A
G
T
G
T
A
G
T
A
T
C
T
G
C
A
A
C
A
A
G
C
G
C
T
T
C
A
C
C
C
A
G
A
A
G
C
0.052838
0.017613
0.041096
0.02544
0.046967
0.02544
0.021526
0.015656
0.04501
0.035225
0.048924
0.013699
0.021526
0.027397
0.037182
0.050881
0.046967
0.037182
0.052838
0.009785
0.007828
0.023483
0.011742
0.04501
0.02544
0.02544
0.056751
0.029354
0.043053
0.015656
0.021526
0.021526
1
4,902
A
C
A
C
T
G
G
T
A
T
G
C
C
C
T
C
A
C
T
C
C
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G
T
G
T
G
T
G
T
C
A
C
C
A
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G
T
G
C
T
T
G
A
T
A
A
G
G
T
A
A
T
C
C
T
T
T
A
A
G
G
A
G
A
T
0.052838
0.017613
0.039139
0.02544
0.048924
0.023483
0.015656
0.013699
0.04501
0.035225
0.054795
0.013699
0.023483
0.031311
0.037182
0.050881
0.046967
0.037182
0.048924
0.007828
0.007828
0.023483
0.015656
0.048924
0.02544
0.019569
0.056751
0.033268
0.043053
0.013699
0.019569
0.023483
1
4,903
G
G
T
A
T
G
C
C
C
T
C
A
C
T
C
C
T
G
T
G
T
G
T
G
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C
A
C
C
A
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T
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C
T
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A
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A
A
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G
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A
A
T
C
C
T
T
T
A
A
G
G
A
G
A
A
G
G
A
G
G
0.054795
0.017613
0.039139
0.029354
0.048924
0.023483
0.013699
0.013699
0.046967
0.035225
0.054795
0.013699
0.023483
0.031311
0.037182
0.048924
0.046967
0.037182
0.048924
0.005871
0.007828
0.023483
0.015656
0.048924
0.027397
0.019569
0.054795
0.033268
0.041096
0.013699
0.019569
0.023483
1
4,904
T
A
T
G
C
C
C
T
C
A
C
T
C
C
T
G
T
G
T
G
T
G
T
C
A
C
C
A
T
G
T
G
C
T
T
G
A
T
A
A
G
G
T
A
A
T
C
C
T
T
T
A
A
G
G
A
G
A
A
G
G
A
G
C
G
G
0.058708
0.017613
0.039139
0.029354
0.048924
0.023483
0.013699
0.013699
0.046967
0.035225
0.054795
0.013699
0.023483
0.031311
0.037182
0.048924
0.04501
0.037182
0.048924
0.005871
0.007828
0.023483
0.015656
0.048924
0.027397
0.019569
0.052838
0.033268
0.041096
0.013699
0.019569
0.023483
1
4,905
T
C
T
G
T
T
G
G
C
G
C
T
C
C
T
T
C
T
C
C
T
T
A
A
A
G
G
A
T
T
A
C
C
T
T
A
T
C
A
A
G
C
A
C
A
T
G
G
T
G
A
C
A
C
A
C
A
C
A
G
G
A
G
T
G
T
0.060665
0.017613
0.041096
0.029354
0.048924
0.021526
0.013699
0.013699
0.046967
0.037182
0.052838
0.015656
0.023483
0.033268
0.039139
0.04501
0.04501
0.033268
0.048924
0.005871
0.007828
0.023483
0.015656
0.048924
0.027397
0.019569
0.054795
0.029354
0.041096
0.013699
0.021526
0.023483
1
4,906
G
T
G
T
G
T
C
A
C
C
A
T
G
T
G
C
T
T
G
A
T
A
A
G
G
T
A
A
T
C
C
T
T
T
A
A
G
G
A
G
A
A
G
G
A
G
C
G
C
C
A
A
C
A
G
A
T
G
C
T
G
C
A
T
T
C
0.060665
0.017613
0.041096
0.029354
0.048924
0.023483
0.011742
0.013699
0.046967
0.037182
0.050881
0.015656
0.02544
0.035225
0.039139
0.046967
0.043053
0.035225
0.043053
0.005871
0.007828
0.021526
0.015656
0.048924
0.027397
0.019569
0.056751
0.029354
0.041096
0.013699
0.021526
0.02544
1
4,907
G
T
G
A
G
A
A
G
C
C
C
C
A
C
C
A
A
T
G
C
A
G
C
A
T
C
T
G
T
T
G
G
C
G
C
T
C
C
T
T
C
T
C
C
T
T
A
A
A
G
G
A
T
T
A
C
C
T
T
A
T
C
A
A
G
T
0.068493
0.021526
0.041096
0.029354
0.052838
0.021526
0.011742
0.015656
0.046967
0.035225
0.052838
0.015656
0.02544
0.035225
0.041096
0.04501
0.04501
0.033268
0.039139
0.003914
0.007828
0.015656
0.015656
0.048924
0.027397
0.021526
0.054795
0.023483
0.043053
0.013699
0.021526
0.02544
1
4,908
A
G
G
A
G
A
A
G
G
A
G
C
G
C
C
A
A
C
A
G
A
T
G
C
T
G
C
A
T
T
G
G
T
G
G
G
G
C
T
T
C
T
C
A
C
C
T
G
T
T
G
A
T
G
T
A
G
G
A
A
G
A
G
A
C
C
0.072407
0.021526
0.041096
0.031311
0.052838
0.019569
0.011742
0.015656
0.046967
0.035225
0.048924
0.017613
0.02544
0.039139
0.041096
0.043053
0.041096
0.035225
0.031311
0.003914
0.007828
0.015656
0.015656
0.048924
0.031311
0.021526
0.050881
0.023483
0.046967
0.013699
0.023483
0.02544
1
4,909
A
G
G
A
G
A
A
G
G
A
G
C
G
C
C
A
A
C
A
G
A
T
G
C
T
G
C
A
T
T
G
G
T
G
G
G
G
C
T
T
C
T
C
A
C
C
T
G
T
T
G
A
T
G
T
A
G
G
A
A
G
A
G
A
C
G
0.072407
0.021526
0.041096
0.031311
0.052838
0.019569
0.011742
0.015656
0.046967
0.035225
0.048924
0.017613
0.02544
0.039139
0.041096
0.043053
0.041096
0.035225
0.031311
0.003914
0.007828
0.015656
0.015656
0.048924
0.031311
0.021526
0.050881
0.023483
0.046967
0.013699
0.023483
0.02544
1
4,910
G
C
C
A
A
C
A
G
A
T
G
C
T
G
C
A
T
T
G
G
T
G
G
G
G
C
T
T
C
T
C
A
C
C
T
G
T
T
G
A
T
G
T
A
G
G
A
A
G
A
G
A
C
A
G
C
A
A
G
C
A
G
G
A
C
G
0.076321
0.023483
0.04501
0.029354
0.052838
0.017613
0.013699
0.015656
0.048924
0.037182
0.048924
0.017613
0.02544
0.037182
0.041096
0.043053
0.041096
0.033268
0.023483
0.005871
0.007828
0.015656
0.015656
0.048924
0.033268
0.019569
0.048924
0.02544
0.04501
0.013699
0.023483
0.02544
1
4,911
A
C
A
G
A
A
C
T
A
C
G
T
C
A
A
G
C
A
C
A
T
G
T
T
C
G
T
A
C
A
C
A
C
A
G
G
T
G
A
G
T
G
T
C
A
C
C
C
C
A
C
C
T
G
G
A
G
G
C
C
T
G
G
C
A
T
0.035225
0.023483
0.046967
0.001957
0.052838
0.033268
0.007828
0.023483
0.04501
0.037182
0.058708
0.005871
0.015656
0.019569
0.02544
0.052838
0.078278
0.052838
0.060665
0.013699
0.007828
0.013699
0.011742
0.027397
0.033268
0.029354
0.04501
0.060665
0.029354
0.011742
0.013699
0.02544
1
4,912
A
A
A
C
A
G
A
A
C
T
A
C
G
T
C
A
A
G
C
A
C
A
T
G
T
T
C
G
T
A
C
A
C
A
C
A
G
G
T
G
A
G
T
G
T
C
A
C
C
C
C
A
C
C
T
G
G
A
G
G
C
C
T
G
G
G
0.035225
0.023483
0.04501
0.001957
0.052838
0.033268
0.007828
0.023483
0.043053
0.039139
0.058708
0.005871
0.015656
0.019569
0.02544
0.052838
0.078278
0.052838
0.060665
0.013699
0.007828
0.013699
0.011742
0.027397
0.033268
0.029354
0.04501
0.062622
0.029354
0.011742
0.013699
0.02544
1
4,913
C
C
T
C
C
A
G
G
T
G
G
G
G
T
G
A
C
A
C
T
C
A
C
C
T
G
T
G
T
G
T
A
C
G
A
A
C
A
T
G
T
G
C
T
T
G
A
C
G
T
A
G
T
T
C
T
G
T
T
T
G
G
C
G
G
A
0.035225
0.023483
0.04501
0.001957
0.052838
0.035225
0.007828
0.023483
0.041096
0.039139
0.058708
0.005871
0.015656
0.019569
0.02544
0.052838
0.078278
0.054795
0.062622
0.013699
0.007828
0.013699
0.011742
0.027397
0.031311
0.029354
0.041096
0.062622
0.029354
0.013699
0.013699
0.02544
1
4,914
T
G
G
G
G
T
G
A
C
A
C
T
C
A
C
C
T
G
T
G
T
G
T
A
C
G
A
A
C
A
T
G
T
G
C
T
T
G
A
C
G
T
A
G
T
T
C
T
G
T
T
T
G
G
C
G
G
T
G
A
A
A
G
T
C
C
0.035225
0.023483
0.046967
0.001957
0.052838
0.035225
0.007828
0.023483
0.041096
0.039139
0.058708
0.005871
0.015656
0.019569
0.02544
0.054795
0.074364
0.052838
0.062622
0.013699
0.007828
0.013699
0.013699
0.029354
0.033268
0.02544
0.041096
0.062622
0.027397
0.013699
0.013699
0.027397
1
4,915
A
G
A
C
T
T
T
C
A
C
C
G
C
C
A
A
A
C
A
G
A
A
C
T
A
C
G
T
C
A
A
G
C
A
C
A
T
G
T
T
C
G
T
A
C
A
C
A
C
A
G
G
T
G
A
G
T
G
T
C
A
C
C
C
C
T
0.035225
0.023483
0.046967
0.001957
0.050881
0.035225
0.007828
0.023483
0.041096
0.039139
0.060665
0.005871
0.015656
0.019569
0.02544
0.054795
0.074364
0.052838
0.062622
0.013699
0.007828
0.013699
0.013699
0.029354
0.033268
0.02544
0.041096
0.062622
0.027397
0.013699
0.013699
0.027397
1
4,916
G
C
A
C
T
C
T
C
T
G
C
A
A
C
A
A
G
A
C
T
T
T
C
A
C
C
G
C
C
A
A
A
C
A
G
A
A
C
T
A
C
G
T
C
A
A
G
C
A
C
A
T
G
T
T
C
G
T
A
C
A
C
A
C
A
G
0.035225
0.023483
0.046967
0.001957
0.048924
0.039139
0.007828
0.023483
0.041096
0.041096
0.060665
0.005871
0.011742
0.015656
0.02544
0.056751
0.078278
0.054795
0.060665
0.013699
0.007828
0.013699
0.011742
0.029354
0.033268
0.023483
0.043053
0.066536
0.021526
0.015656
0.013699
0.027397
1
4,917
G
T
G
T
A
C
G
A
A
C
A
T
G
T
G
C
T
T
G
A
C
G
T
A
G
T
T
C
T
G
T
T
T
G
G
C
G
G
T
G
A
A
A
G
T
C
T
T
G
T
T
G
C
A
G
A
G
A
G
T
G
C
A
C
T
G
0.035225
0.02544
0.04501
0.001957
0.050881
0.039139
0.007828
0.023483
0.041096
0.041096
0.058708
0.005871
0.011742
0.015656
0.027397
0.056751
0.078278
0.054795
0.060665
0.013699
0.007828
0.013699
0.011742
0.029354
0.031311
0.023483
0.043053
0.066536
0.021526
0.015656
0.013699
0.027397
1
4,918
G
C
C
T
T
A
T
G
A
G
T
G
C
A
C
T
C
T
C
T
G
C
A
A
C
A
A
G
A
C
T
T
T
C
A
C
C
G
C
C
A
A
A
C
A
G
A
A
C
T
A
C
G
T
C
A
A
G
C
A
C
A
T
G
T
G
0.033268
0.02544
0.04501
0.001957
0.052838
0.039139
0.007828
0.023483
0.039139
0.04501
0.058708
0.003914
0.011742
0.013699
0.027397
0.056751
0.082192
0.054795
0.060665
0.013699
0.007828
0.013699
0.011742
0.027397
0.031311
0.023483
0.04501
0.068493
0.019569
0.015656
0.011742
0.027397
1
4,919
G
T
T
T
G
G
C
G
G
T
G
A
A
A
G
T
C
T
T
G
T
T
G
C
A
G
A
G
A
G
T
G
C
A
C
T
C
A
T
A
A
G
G
C
T
T
T
T
T
T
T
C
G
C
C
T
T
G
C
C
C
A
C
T
G
T
0.033268
0.02544
0.043053
0.003914
0.050881
0.037182
0.007828
0.023483
0.037182
0.046967
0.056751
0.003914
0.011742
0.015656
0.031311
0.056751
0.082192
0.056751
0.058708
0.011742
0.007828
0.015656
0.011742
0.02544
0.029354
0.021526
0.050881
0.07045
0.017613
0.015656
0.011742
0.027397
1
4,920
A
A
G
A
C
A
C
A
T
C
A
A
A
G
A
A
A
A
G
A
A
C
T
C
A
C
C
C
A
T
G
G
T
A
G
C
A
G
C
T
G
C
A
G
T
T
T
T
G
A
C
T
T
G
A
A
C
A
T
G
G
T
T
C
G
C
0.097847
0.043053
0.039139
0.041096
0.039139
0.033268
0.007828
0.037182
0.041096
0.023483
0.031311
0.011742
0.017613
0.035225
0.039139
0.041096
0.048924
0.041096
0.027397
0.001957
0.005871
0.007828
0.013699
0.031311
0.056751
0.023483
0.037182
0.005871
0.035225
0.009785
0.027397
0.046967
1
4,921
C
C
C
A
C
T
A
T
C
A
G
A
T
C
A
C
T
A
A
G
A
A
C
A
G
A
C
T
G
T
A
C
C
G
G
G
A
A
A
A
T
G
A
C
T
G
C
A
T
G
T
T
C
C
C
C
T
C
A
A
G
G
T
A
A
T
0.033268
0.019569
0.052838
0.027397
0.023483
0.023483
0.007828
0.041096
0.060665
0.029354
0.052838
0.029354
0.031311
0.037182
0.021526
0.029354
0.037182
0.035225
0.023483
0.009785
0.013699
0.003914
0.031311
0.062622
0.050881
0.023483
0.023483
0.021526
0.050881
0.023483
0.02544
0.043053
1
4,922
C
T
T
C
T
G
T
C
T
C
G
G
A
A
A
A
A
C
C
C
A
A
A
A
C
T
T
G
T
T
G
A
T
G
C
A
G
A
A
T
A
C
A
C
C
A
A
A
A
A
C
C
A
G
G
C
C
T
G
G
A
A
A
T
C
G
0.060665
0.031311
0.027397
0.043053
0.041096
0.033268
0.009785
0.04501
0.043053
0.015656
0.037182
0.035225
0.019569
0.039139
0.033268
0.037182
0.054795
0.041096
0.021526
0.003914
0.003914
0.001957
0.031311
0.027397
0.048924
0.031311
0.033268
0.015656
0.033268
0.031311
0.019569
0.048924
1
4,923
C
A
A
G
T
G
A
G
C
C
A
C
A
C
A
G
G
A
A
G
A
G
G
T
G
T
T
T
A
A
A
C
C
G
G
A
A
A
C
T
T
G
C
A
G
C
T
A
C
G
C
C
T
C
G
A
A
A
A
T
T
A
A
A
C
T
0.09002
0.033268
0.048924
0.041096
0.037182
0.023483
0.003914
0.031311
0.041096
0.029354
0.039139
0.037182
0.023483
0.043053
0.027397
0.02544
0.039139
0.04501
0.029354
0.003914
0.005871
0.001957
0.027397
0.02544
0.050881
0.017613
0.02544
0.021526
0.043053
0.017613
0.043053
0.027397
1
4,924
G
G
A
C
G
C
G
G
A
G
G
A
A
G
G
T
C
T
G
C
G
G
C
G
G
T
C
C
T
T
A
C
C
G
T
A
C
A
G
A
A
A
A
T
C
A
T
A
C
G
C
T
C
G
A
T
T
G
G
A
G
G
A
G
A
G
0.017613
0.017613
0.017613
0.005871
0.011742
0.052838
0.023483
0.009785
0.017613
0.031311
0.068493
0.005871
0.015656
0.019569
0.015656
0.027397
0.046967
0.052838
0.078278
0.056751
0.037182
0.062622
0.009785
0.052838
0.019569
0.031311
0.029354
0.072407
0.050881
0.021526
0.005871
0.013699
1
4,925
A
A
A
G
C
A
G
T
C
A
G
C
A
T
C
A
G
G
T
C
C
A
T
G
G
G
G
G
G
T
C
A
T
T
G
T
G
C
T
G
T
G
T
A
G
A
C
T
C
C
C
T
C
C
C
C
C
T
G
G
C
A
G
G
A
C
0.041096
0.029354
0.043053
0.037182
0.039139
0.02544
0.001957
0.041096
0.035225
0.019569
0.04501
0.048924
0.017613
0.048924
0.035225
0.029354
0.04501
0.039139
0.039139
0.007828
0.003914
0.001957
0.009785
0.043053
0.037182
0.023483
0.037182
0.027397
0.039139
0.02544
0.039139
0.043053
1
4,926
G
G
G
G
G
T
C
A
T
T
G
T
G
C
T
G
T
G
T
A
G
A
C
T
C
C
C
T
C
C
C
C
C
T
G
G
C
A
G
G
A
A
C
C
C
A
C
C
T
T
G
C
T
T
T
G
C
C
T
C
A
T
A
G
T
G
0.04501
0.031311
0.043053
0.043053
0.035225
0.02544
0.001957
0.039139
0.037182
0.019569
0.043053
0.037182
0.015656
0.052838
0.037182
0.02544
0.04501
0.043053
0.039139
0.007828
0.003914
0.001957
0.009785
0.041096
0.041096
0.023483
0.039139
0.031311
0.037182
0.021526
0.039139
0.043053
1
4,927
A
T
G
G
C
T
T
G
G
C
C
A
A
T
C
C
T
C
G
T
G
A
T
T
T
C
T
T
G
A
T
A
C
C
C
A
T
T
G
C
C
T
G
G
T
A
T
G
A
G
G
A
T
C
G
C
C
A
A
G
T
A
C
C
A
T
0.084149
0.029354
0.056751
0.04501
0.02544
0.033268
0.007828
0.041096
0.033268
0.023483
0.035225
0.031311
0.023483
0.037182
0.056751
0.021526
0.029354
0.046967
0.017613
0.003914
0.007828
0.003914
0.027397
0.019569
0.043053
0.015656
0.035225
0.031311
0.021526
0.041096
0.033268
0.037182
1
4,928
A
G
G
G
G
C
C
A
A
T
G
G
C
T
T
G
G
C
C
A
A
T
C
C
T
C
G
T
G
A
T
T
T
C
T
T
G
A
T
A
C
C
C
A
T
T
G
C
C
T
G
G
T
A
T
G
A
G
G
A
T
C
G
C
C
C
0.082192
0.031311
0.058708
0.04501
0.027397
0.035225
0.007828
0.039139
0.033268
0.023483
0.037182
0.029354
0.023483
0.035225
0.058708
0.023483
0.029354
0.048924
0.017613
0.003914
0.007828
0.003914
0.02544
0.019569
0.041096
0.013699
0.035225
0.031311
0.021526
0.041096
0.033268
0.035225
1
4,929
C
T
C
A
T
T
G
G
G
C
T
G
T
A
C
A
A
G
C
A
T
C
T
T
G
C
C
A
A
A
C
T
C
G
G
T
G
T
A
A
A
T
G
A
G
A
A
G
G
T
T
C
C
C
T
T
T
C
T
G
C
G
G
A
A
T
0.078278
0.02544
0.054795
0.050881
0.033268
0.021526
0.003914
0.021526
0.058708
0.043053
0.033268
0.023483
0.019569
0.039139
0.043053
0.02544
0.046967
0.031311
0.023483
0.003914
0.003914
0.003914
0.021526
0.035225
0.054795
0.021526
0.048924
0.017613
0.029354
0.007828
0.033268
0.041096
1
4,930
C
T
T
G
C
C
A
A
A
C
T
C
G
G
T
G
T
A
A
A
T
G
A
G
A
A
G
G
T
T
C
C
C
T
T
T
C
T
G
C
G
G
A
A
C
T
G
A
C
A
A
A
A
A
A
A
G
A
C
A
G
G
G
C
A
T
0.078278
0.027397
0.054795
0.050881
0.035225
0.021526
0.003914
0.023483
0.056751
0.041096
0.033268
0.021526
0.019569
0.039139
0.046967
0.02544
0.046967
0.031311
0.023483
0.003914
0.003914
0.003914
0.017613
0.035225
0.054795
0.021526
0.050881
0.017613
0.029354
0.009785
0.029354
0.041096
1
4,931
G
T
G
G
G
T
C
T
C
T
C
C
C
A
G
G
G
C
C
T
G
C
A
T
A
C
C
T
T
G
T
G
T
G
G
A
G
C
T
G
G
A
G
A
C
A
T
A
A
A
G
T
C
T
A
A
C
A
A
T
G
G
G
C
T
G
0.04501
0.031311
0.037182
0.035225
0.041096
0.033268
0.005871
0.029354
0.043053
0.019569
0.052838
0.037182
0.011742
0.048924
0.041096
0.031311
0.035225
0.054795
0.035225
0.005871
0
0
0.031311
0.041096
0.037182
0.031311
0.02544
0.037182
0.043053
0.015656
0.027397
0.035225
1
4,932
G
C
C
C
A
T
T
G
T
T
A
G
A
C
T
T
T
A
T
G
T
C
T
C
C
A
G
C
T
C
C
A
C
A
C
A
A
G
G
T
A
T
G
C
A
G
G
C
C
C
T
G
G
G
A
G
A
G
A
C
C
C
A
C
A
A
0.043053
0.031311
0.037182
0.035225
0.041096
0.033268
0.005871
0.029354
0.043053
0.019569
0.052838
0.039139
0.011742
0.048924
0.041096
0.031311
0.035225
0.054795
0.035225
0.005871
0
0
0.031311
0.041096
0.037182
0.031311
0.02544
0.037182
0.043053
0.015656
0.027397
0.035225
1
4,933
T
C
A
A
A
G
G
G
C
T
T
G
T
G
A
G
A
A
A
C
T
G
A
A
G
G
T
A
G
A
A
T
C
C
T
A
T
A
C
A
G
C
C
A
G
C
T
A
G
A
G
G
G
A
A
A
A
A
C
A
T
A
C
A
A
A
0.058708
0.02544
0.046967
0.039139
0.041096
0.029354
0.003914
0.039139
0.035225
0.035225
0.037182
0.039139
0.031311
0.046967
0.037182
0.035225
0.04501
0.043053
0.015656
0
0.003914
0
0.029354
0.02544
0.04501
0.021526
0.017613
0.029354
0.021526
0.031311
0.027397
0.062622
1
4,934
C
C
A
C
A
C
A
T
A
G
A
G
G
A
G
A
G
A
G
A
A
A
A
T
G
G
C
T
G
A
G
T
T
A
A
A
G
G
T
A
A
G
A
A
A
C
C
A
T
C
T
G
A
C
A
A
G
T
T
T
G
C
T
A
T
C
0.064579
0.041096
0.064579
0.031311
0.041096
0.031311
0.001957
0.033268
0.048924
0.039139
0.039139
0.027397
0.011742
0.019569
0.04501
0.035225
0.048924
0.043053
0.023483
0.007828
0
0.005871
0.013699
0.033268
0.064579
0.021526
0.017613
0.023483
0.035225
0.009785
0.029354
0.046967
1
4,935
T
G
T
C
A
G
A
T
G
G
T
T
T
C
T
T
A
C
C
T
T
T
A
A
C
T
C
A
G
C
C
A
T
T
T
T
C
T
C
T
C
T
C
C
T
C
T
A
T
G
T
G
T
G
G
T
G
A
C
T
T
C
A
G
G
C
0.064579
0.043053
0.064579
0.031311
0.041096
0.031311
0.001957
0.035225
0.046967
0.039139
0.039139
0.027397
0.011742
0.019569
0.041096
0.037182
0.048924
0.043053
0.023483
0.007828
0
0.005871
0.013699
0.033268
0.064579
0.019569
0.017613
0.023483
0.035225
0.009785
0.031311
0.046967
1
4,936
T
C
A
T
C
C
C
T
T
G
C
C
C
T
G
G
A
G
A
G
A
C
G
G
C
A
G
A
A
C
C
A
T
G
G
C
A
T
T
T
T
A
T
A
G
C
T
G
C
T
G
C
T
G
G
G
T
C
C
T
C
T
T
G
G
C
0.048924
0.013699
0.048924
0.033268
0.027397
0.021526
0.009785
0.021526
0.07045
0.033268
0.046967
0.015656
0.031311
0.029354
0.039139
0.031311
0.048924
0.052838
0.039139
0.007828
0.001957
0.003914
0.021526
0.052838
0.037182
0.023483
0.039139
0.041096
0.04501
0.011742
0.021526
0.029354
1
4,937
T
C
A
T
C
C
C
T
T
G
C
C
C
T
G
G
A
G
A
G
A
C
G
G
C
A
G
A
A
C
C
A
T
G
G
C
A
T
T
T
T
A
T
A
G
C
T
G
C
T
G
C
T
G
G
G
T
C
C
T
C
T
T
G
G
G
0.048924
0.013699
0.048924
0.033268
0.027397
0.021526
0.009785
0.021526
0.07045
0.033268
0.046967
0.015656
0.031311
0.029354
0.039139
0.031311
0.048924
0.052838
0.039139
0.007828
0.001957
0.003914
0.021526
0.052838
0.037182
0.023483
0.039139
0.041096
0.04501
0.011742
0.021526
0.029354
1
4,938
A
G
G
A
A
A
G
A
G
C
C
C
C
C
C
A
A
G
G
A
T
A
A
T
G
T
C
C
C
C
C
T
T
C
T
T
T
T
G
G
G
C
T
C
G
C
T
G
G
T
C
T
G
G
C
C
C
G
T
A
G
G
C
A
G
C
0.054795
0.017613
0.04501
0.046967
0.023483
0.021526
0.009785
0.021526
0.062622
0.037182
0.041096
0.023483
0.035225
0.023483
0.046967
0.027397
0.046967
0.046967
0.043053
0.007828
0.001957
0.003914
0.023483
0.046967
0.039139
0.019569
0.037182
0.035225
0.039139
0.011742
0.023483
0.035225
1
4,939
A
G
A
A
G
G
G
G
G
A
C
A
T
T
A
T
C
C
T
T
G
G
G
G
G
G
C
T
C
T
T
T
C
C
T
A
T
T
C
A
T
T
T
T
G
G
A
G
T
A
G
C
A
G
C
T
A
A
A
G
A
T
C
A
A
G
0.07045
0.015656
0.050881
0.041096
0.021526
0.021526
0.009785
0.023483
0.062622
0.037182
0.041096
0.023483
0.031311
0.021526
0.043053
0.027397
0.046967
0.04501
0.043053
0.007828
0.001957
0.003914
0.023483
0.043053
0.039139
0.021526
0.037182
0.035225
0.037182
0.011742
0.027397
0.033268
1
4,940
A
G
A
C
T
C
C
G
G
C
C
T
T
G
A
T
T
T
G
A
G
A
T
C
T
T
G
A
T
C
T
T
T
A
G
C
T
G
C
T
A
C
T
C
C
A
A
A
A
T
G
A
A
T
A
G
G
A
A
A
G
A
G
C
C
C
0.07045
0.015656
0.050881
0.043053
0.023483
0.019569
0.005871
0.02544
0.058708
0.037182
0.041096
0.023483
0.033268
0.02544
0.04501
0.023483
0.046967
0.043053
0.043053
0.007828
0.001957
0.003914
0.023483
0.043053
0.037182
0.021526
0.037182
0.035225
0.037182
0.013699
0.02544
0.037182
1
4,941
A
C
A
G
A
C
T
C
C
G
G
C
C
T
T
G
A
T
T
T
G
A
G
A
T
C
T
T
G
A
T
C
T
T
T
A
G
C
T
G
C
T
A
C
T
C
C
A
A
A
A
T
G
A
A
T
A
G
G
A
A
A
G
A
G
G
0.07045
0.015656
0.050881
0.041096
0.023483
0.019569
0.005871
0.02544
0.060665
0.037182
0.041096
0.023483
0.031311
0.02544
0.04501
0.023483
0.046967
0.043053
0.043053
0.007828
0.001957
0.003914
0.023483
0.043053
0.039139
0.021526
0.037182
0.035225
0.037182
0.013699
0.02544
0.037182
1
4,942
T
T
G
G
A
G
T
A
G
C
A
G
C
T
A
A
A
G
A
T
C
A
A
G
A
T
C
T
C
A
A
A
T
C
A
A
G
G
C
C
G
G
A
G
T
C
T
G
T
G
G
A
A
T
G
T
A
T
C
A
G
G
T
A
A
C
0.074364
0.015656
0.050881
0.041096
0.017613
0.019569
0.005871
0.02544
0.056751
0.037182
0.043053
0.023483
0.031311
0.029354
0.043053
0.021526
0.04501
0.046967
0.043053
0.007828
0.001957
0.003914
0.021526
0.043053
0.039139
0.019569
0.041096
0.039139
0.039139
0.011742
0.02544
0.035225
1
4,943
A
G
C
A
G
C
T
A
A
A
G
A
T
C
A
A
G
A
T
C
T
C
A
A
A
T
C
A
A
G
G
C
C
G
G
A
G
T
C
T
G
T
G
G
A
A
T
G
T
A
T
C
A
G
G
T
A
A
G
A
A
G
A
G
G
T
0.076321
0.017613
0.052838
0.041096
0.017613
0.019569
0.005871
0.02544
0.056751
0.037182
0.043053
0.023483
0.031311
0.029354
0.043053
0.019569
0.046967
0.04501
0.039139
0.007828
0.001957
0.003914
0.021526
0.043053
0.039139
0.017613
0.041096
0.039139
0.037182
0.011742
0.029354
0.035225
1
4,944
A
A
G
A
G
A
T
T
G
G
C
A
G
A
T
T
A
G
G
C
C
C
C
T
C
T
T
C
T
T
A
C
C
T
G
A
T
A
C
A
T
T
C
C
A
C
A
G
A
C
T
C
C
G
G
C
C
T
T
G
A
T
T
T
G
A
0.078278
0.015656
0.052838
0.043053
0.017613
0.027397
0.005871
0.019569
0.056751
0.037182
0.043053
0.023483
0.031311
0.031311
0.04501
0.023483
0.043053
0.048924
0.037182
0.007828
0.001957
0.003914
0.021526
0.039139
0.037182
0.019569
0.037182
0.039139
0.033268
0.011742
0.029354
0.037182
1
4,945
T
T
G
G
A
A
G
C
C
A
C
C
C
T
G
A
G
T
T
T
T
G
T
T
G
C
T
C
A
A
A
A
C
A
A
A
A
T
T
G
A
T
T
C
T
T
T
G
A
A
C
C
T
T
G
A
T
G
A
G
T
T
C
T
G
A
0.048924
0.031311
0.050881
0.029354
0.021526
0.027397
0.015656
0.02544
0.048924
0.046967
0.035225
0.027397
0.023483
0.023483
0.048924
0.02544
0.052838
0.054795
0.043053
0.009785
0.005871
0.007828
0.019569
0.033268
0.048924
0.013699
0.041096
0.041096
0.031311
0.019569
0.013699
0.033268
1
4,946
T
A
G
A
G
G
G
A
A
T
G
T
G
C
T
C
T
G
A
G
C
A
G
T
T
G
C
A
G
A
A
C
T
C
A
T
C
A
A
G
G
T
T
C
A
A
A
G
A
A
T
C
A
A
T
T
T
T
G
T
T
T
T
G
A
G
0.046967
0.031311
0.048924
0.029354
0.023483
0.023483
0.015656
0.027397
0.046967
0.04501
0.033268
0.035225
0.027397
0.029354
0.046967
0.02544
0.050881
0.050881
0.041096
0.009785
0.005871
0.007828
0.021526
0.033268
0.046967
0.011742
0.041096
0.039139
0.031311
0.021526
0.015656
0.035225
1