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CCN1, a candidate target for zoledronic acid treatment in breast cancer.
CCN1, also known as CYR61, is a survival and proangiogenic factor overexpressed in about 30% of invasive breast carcinomas, and particularly in triple-negative breast carcinomas (TNBC). CCN1 expression in breast cancer promotes tumorigenicity, metastasis, antihormone, and chemoresistance. TNBCs often develop bone metas...
10.1158/1535-7163.MCT-10-0836
21,393,426
D000970:Antineoplastic Agents; D017209:Apoptosis; D001943:Breast Neoplasms; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D055515:Cysteine-Rich Protein 61; D004164:Diphosphonates; D005260:Female; D000071316:Forkhead Box Protein O3; D051858:Forkhead Transcription Factors; D015870:Gene Expression; D015972:Gene Ex...
Molecular cancer therapeutics
2,011
D000970:Antineoplastic Agents; D055515:Cysteine-Rich Protein 61; D004164:Diphosphonates; C499517:FOXO3 protein, human; D000071316:Forkhead Box Protein O3; D051858:Forkhead Transcription Factors; D007093:Imidazoles; D000077211:Zoledronic Acid; D051057:Proto-Oncogene Proteins c-akt
Postoperative cervical sagittal imbalance negatively affects outcomes after surgery for cervical spondylotic myelopathy.
STUDY DESIGN Prospective observational cohort study. OBJECTIVE To determine if postoperative cervical sagittal balance is an independent predictor of health-related quality of life outcome after surgery for cervical spondylotic myelopathy. SUMMARY OF BACKGROUND DATA Both ventral and dorsal fusion procedures for CSM...
10.1097/BRS.0000000000000641
25,419,682
D000368:Aged; D002574:Cervical Vertebrae; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D004856:Postural Balance; D011446:Prospective Studies; D011788:Quality of Life; D012678:Sensation Disorders; D013123:Spinal Fusion; D055009:Spondylosis; D016896:Treatment Out...
Spine
2,014
Green tea consumption and the risk of liver cancer in Japan: the Ohsaki Cohort study.
OBJECTIVES To investigate the association between green tea consumption and liver cancer incidence. METHODS We prospectively followed 41,761 Japanese adults aged 40-79 years, without a history of cancer at the baseline or any missing data for green tea consumption frequency. Cox proportional hazards models were used ...
10.1007/s10552-009-9388-x
19,768,563
D000328:Adult; D000368:Aged; D001628:Beverages; D002277:Carcinoma; D015331:Cohort Studies; D004327:Drinking Behavior; D004435:Eating; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan; D008113:Liver Neoplasms; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D012307:Risk Factors; D013662:Tea
Cancer causes & control : CCC
2,009
D013662:Tea
Development of a receptor based signal amplified fluorescence polarization assay for multi-detection of 35 sulfonamides in pork.
With the increasing focus on food security, a screening method with high-throughput, ultra-sensitivity, and user-friendly operation is urgently needed for monitoring of sulfonamides residues in animal-derived foods. In this study, the sulfonamides' receptor dihydropteroate synthase of Staphylococcus aureus was subjecte...
10.1016/j.fochx.2023.100867
37,780,256
Food chemistry: X
2,023
Influence of the porosity of starch-based fiber mesh scaffolds on the proliferation and osteogenic differentiation of bone marrow stromal cells cultured in a flow perfusion bioreactor.
This study investigates the influence of the porosity of fiber mesh scaffolds obtained from a blend of starch and poly(epsilon-caprolactone) on the proliferation and osteogenic differentiation of marrow stromal cells cultured under static and flow perfusion conditions. For this purpose, biodegradable scaffolds were fab...
10.1089/ten.2006.12.801
16,674,293
D000818:Animals; D019149:Bioreactors; D001854:Bone Marrow Cells; D002454:Cell Differentiation; D002478:Cells, Cultured; D045424:Complex Mixtures; D008297:Male; D011091:Polyesters; D016062:Porosity; D051381:Rats; D017208:Rats, Wistar; D013213:Starch; D017154:Stromal Cells; D023822:Tissue Engineering; D014057:Tomography,...
Tissue engineering
2,006
D045424:Complex Mixtures; D011091:Polyesters; C016240:polycaprolactone; D013213:Starch
Prognostic nutritional index as a prognostic marker in glioblastoma: Data from a cohort of 282 Italian patients.
Preoperative prognostic nutritional index (PNI) is linked to the clinical outcome of patients with malignant tumours, however few studies have investigated its utility in predicting outcome in glioblastoma multiforme (GBM). We performed a retrospective study on adult patients with GBM in order to evaluate the impact of...
10.1016/j.jns.2019.04.002
30,974,322
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000927:Anticonvulsants; D001932:Brain Neoplasms; D015331:Cohort Studies; D005260:Female; D005909:Glioblastoma; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D011379:Prognosis; D012189:Retrospective Studies
Journal of the neurological sciences
2,019
D000927:Anticonvulsants
Children's interstitial and diffuse lung disease.
Children's interstitial and diffuse lung disease (chILD) is a rare heterogenous group of conditions, with symptoms often overlapping with more common conditions, impeding diagnosis and frustrating parents and clinicians alike. Clinical collaborations are improving diagnostic precision, disease phenotyping, mechanistic ...
10.1016/S2352-4642(19)30117-8
31,227,433
D002648:Child; D036262:Empirical Research; D006801:Humans; D017563:Lung Diseases, Interstitial; D010290:Parents; D010348:Patient Care Team
The Lancet. Child & adolescent health
2,019
A profile of methylphenidate exposures.
INTRODUCTION Methylphenidate is prescribed commonly for children with attention deficit hyperactivity disorder. An estimated 2.8% of US youths aged 5 to 18 years use it for the management of this disorder. Despite the widespread use of methylphenidate, the demographics and outcome of intentional and unintentional expos...
10.1081/clt-100102011
11,185,969
D000293:Adolescent; D000328:Adult; D000697:Central Nervous System Stimulants; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008774:Methylphenidate; D011039:Poison Control Centers; D011041:Poisoning; D012189:Retrospective Studies
Journal of toxicology. Clinical toxicology
2,000
D000697:Central Nervous System Stimulants; D008774:Methylphenidate
[Experience with neuroendoscopic treatment of 12 patients with obstructive hydrocephalus due to aqueduct lesions].
OBJECTIVE To review our experience in the treatment of hydrocephalus caused by aqueduct obstruction with neuroendoscopic third ventriculostomy. METHOD Of the 12 patients with hydrocephalus, 10 had primary aqueduct obstruction with the other 2 suffering the obstruction secondary to tectal tumors. In all the cases the ...
15,090,320
D000293:Adolescent; D000328:Adult; D002535:Cerebral Aqueduct; D002648:Child; D002675:Child, Preschool; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus; D007223:Infant; D008297:Male; D011183:Postoperative Complications; D014696:Ventriculostomy
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA
2,004
Insights into the microbial response mechanisms to ciprofloxacin during sulfur-mediated biological wastewater treatment using a metagenomics approach.
The fate and removal of ciprofloxacin, a class of fluoroquinolone antibiotic, during sulfur-mediated biological wastewater treatment has been recently well documented. However, little is known regarding the genetic response of microorganisms to ciprofloxacin. Here, a lab-scale anaerobic sulfate-reducing bioreactor was ...
10.1016/j.watres.2022.118995
36,007,398
D000255:Adenosine Triphosphate; D000900:Anti-Bacterial Agents; D019149:Bioreactors; D002244:Carbon; D002939:Ciprofloxacin; D045304:Cytochromes c; D056186:Metagenomics; D009243:NAD; D013431:Sulfates; D013455:Sulfur; D062065:Wastewater; D018508:Water Purification
Water research
2,022
D000900:Anti-Bacterial Agents; D013431:Sulfates; D062065:Waste Water; D009243:NAD; D002939:Ciprofloxacin; D013455:Sulfur; D002244:Carbon; D000255:Adenosine Triphosphate; D045304:Cytochromes c
Metastatic Group 3 Medulloblastoma in a Patient With Tuberous Sclerosis Complex: Case Description and Molecular Characterization of the Tumor.
Medulloblastoma is the most common pediatric brain tumor. We describe a child with tuberous sclerosis complex that developed a Group 3, myc overexpressed, metastatic medulloblastoma (MB). Considering the high risk of treatment-induced malignancies, a tailored therapy, omitting radiation, was given. Based on the evidenc...
10.1002/pbc.25851
26,626,406
D015153:Blotting, Western; D002528:Cerebellar Neoplasms; D004252:DNA Mutational Analysis; D005260:Female; D006801:Humans; D008527:Medulloblastoma; D058570:TOR Serine-Threonine Kinases; D014402:Tuberous Sclerosis
Pediatric blood & cancer
2,016
C546842:MTOR protein, human; D058570:TOR Serine-Threonine Kinases
Ghrelin ameliorates cardiac fibrosis after myocardial infarction by regulating the Nrf2/NADPH/ROS pathway.
To evaluate the role of ghrelin in cardiac fibrosis after myocardial infarction (MI) and to investigate the underlying mechanisms of ghrelin-regulated Nrf2/NADPH/ROS pathway-mediated cardioprotection, the profile of Nrf2, fibrosis markers, and oxidative stress markers were characterized in a rat model of MI and Angiote...
10.1016/j.peptides.2021.170613
34,314,760
D000818:Animals; D002316:Cardiotonic Agents; D002465:Cell Movement; D003094:Collagen; D055513:Connective Tissue Growth Factor; D005347:Fibroblasts; D005355:Fibrosis; D054439:Ghrelin; D008297:Male; D008315:Malondialdehyde; D009203:Myocardial Infarction; D009206:Myocardium; D009249:NADP; D019255:NADPH Oxidases; D051267:N...
Peptides
2,021
C526316:CCN2 protein, rat; D002316:Cardiotonic Agents; D054439:Ghrelin; D051267:NF-E2-Related Factor 2; C495637:Nfe2l2 protein, rat; D017382:Reactive Oxygen Species; D020097:Natriuretic Peptide, Brain; D055513:Connective Tissue Growth Factor; D008315:Malondialdehyde; D009249:NADP; D003094:Collagen; D019255:NADPH Oxidas...
EBV replicon vector system enhances transgene expression in vivo: applications to cancer gene therapy.
BACKGROUND A major limitation of current cancer gene therapies is low and transient expression of the therapeutic gene. For long-term expression of transgenes in vivo, an Epstein-Barr virus (EBV) replicon vector has been developed. The present study examines the effect of the EBV replicon vector system and its applicat...
10.1002/jgm.199
11,529,664
D000818:Animals; D002478:Cells, Cultured; D019309:Epstein-Barr Virus Nuclear Antigens; D005786:Gene Expression Regulation; D017930:Genes, Reporter; D015316:Genetic Therapy; D005822:Genetic Vectors; D004854:Herpesvirus 4, Human; D006801:Humans; D008081:Liposomes; D008156:Luciferases; D008546:Melanoma, Experimental; D051...
The journal of gene medicine
2,001
D019309:Epstein-Barr Virus Nuclear Antigens; D008081:Liposomes; D011994:Recombinant Proteins; D008156:Luciferases; C417029:EBV-encoded nuclear antigen 1
Integration of CREB and bHLH transcriptional signaling pathways through direct heterodimerization of the proteins: role in muscle and testis development.
The cAMP response element binding protein/activating transcription factor (CREB/ATF) family of transcription factors is hormone responsive and critical for nearly all mammalian cell types. The basic helix-loop-helix (bHLH) family of transcription factors is important during the development and differentiation of a wide...
10.1002/mrd.20902
18,361,414
D051701:Activating Transcription Factor 4; D000818:Animals; D051792:Basic Helix-Loop-Helix Transcription Factors; D002460:Cell Line; D002478:Cells, Cultured; D017362:Cyclic AMP Response Element-Binding Protein; D019281:Dimerization; D018257:Helix-Loop-Helix Motifs; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; ...
Molecular reproduction and development
2,008
C081452:Atf4 protein, mouse; D051792:Basic Helix-Loop-Helix Transcription Factors; D017362:Cyclic AMP Response Element-Binding Protein; C503815:Scx protein, mouse; C093234:Tcf15 protein, mouse; D051701:Activating Transcription Factor 4
Comparison of reorganization of the somatosensory system in rats that sustained forelimb removal as neonates and as adults.
Studies of sensory pathways in several species indicate that the extent and form of reorganization resulting from deafferentation early in life vs. adulthood are not the same. The reasons for such differences are not well understood. To gain further insight into age-dependent mechanisms of reorganization, this study co...
10.1002/cne.10849
12,966,559
D000200:Action Potentials; D000367:Age Factors; D000671:Amputation, Surgical; D000818:Animals; D000831:Animals, Newborn; D001931:Brain Mapping; D005260:Female; D005552:Forelimb; D008297:Male; D009475:Neurons, Afferent; D051381:Rats; D017207:Rats, Sprague-Dawley; D013003:Somatosensory Cortex
The Journal of comparative neurology
2,003
Kinematic analysis of sit to stand by persons with rheumatoid arthritis supported by a service dog.
PURPOSE The objective of this study was to quantify the kinesiological effect of the assistance provided by service dogs on transferring from sit to stand in persons with rheumatoid arthritis (RA). METHODS Twenty-four participants performed a total of eight experimental transfers of sit to stand, including unassisted...
10.3109/17483107.2011.562958
22,292,513
D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000818:Animals; D001172:Arthritis, Rheumatoid; D001696:Biomechanical Phenomena; D004185:Disability Evaluation; D004285:Dogs; D004734:Energy Metabolism; D015444:Exercise; D005260:Female; D006305:Health Status Indicators; D006621:Hip Joint; D006801:Humans; D0216...
Disability and rehabilitation. Assistive technology
2,012
Inhibition of CXCR4 inhibits the proliferation and osteogenic potential of fibroblasts from ankylosing spondylitis via the Wnt/β‑catenin pathway.
Ankylosing spondylitis (AS) is an autoimmune condition characterized by chronic inflammation and abnormal ossification as the primary features of the disease. The aim of the present study was to investigate the role of C‑X‑C chemokine receptor type 4 (CXCR4) in ossification from patients with AS. CXCR4 expression was a...
10.3892/mmr.2019.9980
30,816,502
D000328:Adult; D000368:Aged; D015415:Biomarkers; D002454:Cell Differentiation; D049109:Cell Proliferation; D005260:Female; D005347:Fibroblasts; D015870:Gene Expression; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010012:Osteogenesis; D019718:Receptors, CXCR4; D060449:Wnt Signaling ...
Molecular medicine reports
2,019
D015415:Biomarkers; C527276:CXCR4 protein, human; D019718:Receptors, CXCR4
Liver Imaging Reporting and Data System Version 2018: Impact on Categorization and Hepatocellular Carcinoma Staging.
The purpose of this study was to assess the concordance in categorization and radiologic T staging using Liver Imaging Reporting and Data System (LI-RADS, LR) version 2017 (v2017), version 2018 (v2018), and the Organ Procurement and Transplantation Network (OPTN) criteria. All magnetic resonance imaging and computed to...
10.1002/lt.25614
31,344,753
D000368:Aged; D006528:Carcinoma, Hepatocellular; D000078327:Data Systems; D005260:Female; D006801:Humans; D008099:Liver; D008113:Liver Neoplasms; D016031:Liver Transplantation; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012107:Research Design; D012189:Retrospective...
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
2,019
Tamoxifen aziridine binding to cytosolic proteins from human breast specimens is negatively associated with estrogen receptors, progesterone receptors, pS2, and cathepsin-D.
[3H]Tamoxifen Aziridine ([3H]TAZ) is a derivative of the antiestrogen tamoxifen that covalently labels the Estrogen Receptor (ER), and perhaps other uncharacterized proteins. In a previous article we described that [3H]TAZ binds to a cytosolic protein from human uterine tissues that shares some, but not all, the ER pro...
10.1023/a:1006062510883
9,822,220
D014408:Biomarkers, Tumor; D001943:Breast Neoplasms; D002402:Cathepsin D; D004591:Electrophoresis, Polyacrylamide Gel; D004965:Estrogen Antagonists; D005260:Female; D006801:Humans; D009376:Neoplasms, Hormone-Dependent; D011506:Proteins; D018160:Receptors, Cytoplasmic and Nuclear; D011960:Receptors, Estrogen; D011980:Re...
Breast cancer research and treatment
1,998
D014408:Biomarkers, Tumor; D004965:Estrogen Antagonists; D011506:Proteins; D018160:Receptors, Cytoplasmic and Nuclear; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; C051838:TFF1 protein, human; D000071163:Trefoil Factor-1; D025521:Tumor Suppressor Proteins; D013629:Tamoxifen; C031859:tamoxifen aziridine...
Fluorometric determination of acid proteinase activity in vulvovaginal candidosis.
Vulvovaginal candidosis is one of the most frequent disorders in obstetrics and gynaecology. Candida albicans is commonly considered to be the true vaginopathic agent. The secreted acid proteinase might be especially relevant in the pathogenesis of vulvovaginal candidosis. A fluorometric determination of acid proteinas...
10.1111/j.1439-0507.1996.tb00151.x
9,009,656
D000328:Adult; D016282:Aspartic Acid Endopeptidases; D002176:Candida albicans; D002181:Candidiasis, Vulvovaginal; D005260:Female; D005450:Fluorescamine; D006801:Humans; D013050:Spectrometry, Fluorescence; D013379:Substrate Specificity
Mycoses
1,996
D005450:Fluorescamine; D016282:Aspartic Acid Endopeptidases
[Comparative analysis of isolation methods of DNA from rhizosphere soil for research of microbiocenosis].
The comparative analysis of different methods for the isolation of microbial DNA from ordinary black earth and dark-gray podzolic soil of soybean rhizosphere was carried out. All preparations of DNA which isolated from dark-gray podzolic soil after purification using highly dispersed silica (AppliChem, Germany) were su...
25,199,339
D004269:DNA, Bacterial; D004587:Electrophoresis, Agar Gel; D018517:Plant Roots; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S; D058441:Rhizosphere; D012988:Soil Microbiology; D013025:Glycine max; D014455:Ukraine
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993)
2,014
D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S
Bile acid sequestrants for glycemic control in patients with type 2 diabetes: A systematic review with meta-analysis of randomized controlled trials.
AIM To evaluate the effects of bile acid sequestrants (BASs) versus placebo, no intervention or active comparators on glycemic control in type 2 diabetes. METHODS Data were retrieved and a systematic review with meta-analyses was performed. We evaluated bias control and subgroup and sensitivity analyses were performe...
10.1016/j.jdiacomp.2017.01.011
28,238,556
D001647:Bile Acids and Salts; D000069472:Colesevelam Hydrochloride; D003924:Diabetes Mellitus, Type 2; D004811:Epichlorohydrin; D006442:Glycated Hemoglobin; D006801:Humans; D006943:Hyperglycemia; D007003:Hypoglycemia; D007004:Hypoglycemic Agents; D007093:Imidazoles; D016032:Randomized Controlled Trials as Topic; D01520...
Journal of diabetes and its complications
2,017
D001647:Bile Acids and Salts; D006442:Glycated Hemoglobin A; D007004:Hypoglycemic Agents; D007093:Imidazoles; D012117:Resins, Synthetic; D064449:Sequestering Agents; C417427:colestimide; C517652:hemoglobin A1c protein, human; D004811:Epichlorohydrin; D000069472:Colesevelam Hydrochloride
Epileptogenesis in diacylglycerol kinase epsilon deficiency up-regulates COX-2 and tyrosine hydroxylase in hippocampus.
Diacylglycerol kinase (DGK) phosphorylates the second messenger diacylglycerol (DAG) to yield phosphatidic acid, two neural signaling elements that function to modulate synaptic activity. Of the nine mammalian DGK isotypes known, DGK epsilon (DGKepsilon) shows specificity for arachidonoyldiacylglycerol (20:4-DAG) and s...
10.1016/j.bbrc.2005.08.109
16,137,646
D000818:Animals; D051546:Cyclooxygenase 2; D019852:Diacylglycerol Kinase; D004827:Epilepsy; D005786:Gene Expression Regulation; D006624:Hippocampus; D051379:Mice; D018345:Mice, Knockout; D012333:RNA, Messenger; D014446:Tyrosine 3-Monooxygenase; D015854:Up-Regulation
Biochemical and biophysical research communications
2,005
D012333:RNA, Messenger; D014446:Tyrosine 3-Monooxygenase; D051546:Cyclooxygenase 2; D019852:Diacylglycerol Kinase
Percutaneous trans-ulnar artery approach for coronary angiography and angioplasty; A case series study.
BACKGROUND Coronary angiography is the gold standard method for diagnosis of coronary heart disease and usually performed by femoral approach that has several complications. To reduce these complications, upper extremity approach is increasingly used and is becoming preferred access site by many interventionists. Altho...
26,715,936
ARYA atherosclerosis
2,015
Effects of imidazoline I2 receptor agonists on reserpine-induced hyperalgesia and depressive-like behavior in rats.
Pharmacotherapies for fibromyalgia treatment are lacking. This study examined the antinociceptive and antidepressant-like effects of imidazoline I2 receptor (I2R) agonists in a reserpine-induced model of fibromyalgia in rats. Rats were treated for 3 days with vehicle or reserpine. The von Frey filament test was used to...
10.1097/FBP.0000000000000454
30,383,551
D000700:Analgesics; D000818:Animals; D001572:Benzofurans; D003863:Depression; D004195:Disease Models, Animal; D005356:Fibromyalgia; D006930:Hyperalgesia; D019329:Idazoxan; D007093:Imidazoles; D054755:Imidazoline Receptors; D048288:Imidazolines; D008297:Male; D010146:Pain; D010147:Pain Measurement; D011799:Quinazolines;...
Behavioural pharmacology
2,019
D000700:Analgesics; D001572:Benzofurans; C000596974:CR4056; D007093:Imidazoles; D054755:Imidazoline Receptors; D048288:Imidazolines; D011799:Quinazolines; C487767:imidazoline receptor 2; C000605851:phenyzoline; C103723:2-(2-benzofuranyl)-2-imidazoline; D012110:Reserpine; D019329:Idazoxan
A prospective intervention to improve happiness and reduce burnout in oncologists.
BACKGROUND There is a paucity of data about effective interventions to improve happiness and reduce burnout in oncologists. Benjamin Franklin developed a 13-week program of "necessary activities" or "virtues" (temperance, silence, order, resolution, frugality, industry, sincerity, justice, moderation, cleanliness, tran...
10.1007/s00520-018-4567-5
30,506,102
D000328:Adult; D000368:Aged; D002055:Burnout, Professional; D000077062:Burnout, Psychological; D005221:Fatigue; D005260:Female; D006240:Happiness; D006801:Humans; D007588:Job Satisfaction; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D000072103:Oncologists; D010551:Personality; D010555:Personality I...
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
2,019
[Controlled kinesitherapy of patients after surgical myocardial revascularisation in early rehabilitation period].
Kinesitherapy in the form of controlled individually dose-adjusted aerobic exercise in patients early (2-4 weeks) after surgical revascularization of the myocardium increases physical performance and cardiorespiratory reserve of the organism. The above kinesitherapy is indicated for all the patients early after surgica...
15,052,836
D005080:Exercise Test; D005081:Exercise Therapy; D006439:Hemodynamics; D006801:Humans; D008875:Middle Aged; D008991:Monitoring, Physiologic; D017202:Myocardial Ischemia; D009204:Myocardial Revascularization; D013997:Time Factors; D016896:Treatment Outcome
Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury
2,004
Protective effect of predator species richness on human hantavirus infection incidence.
Are predators of rodents beneficial for public health? This question focuses on whether predators regulate the spillover transmission of rodent-borne diseases. No clear answer has emerged because of the complex linkages across multiple trophic levels and the lack of accessible data. Although previous empirical findings...
10.1038/s41598-020-78765-6
33,303,876
D000818:Animals; D044822:Biodiversity; D003247:Conservation of Natural Resources; D020387:Food Chain; D018778:Hantavirus Infections; D006480:Hemorrhagic Fever with Renal Syndrome; D006801:Humans; D011634:Public Health; D056910:Republic of Korea; D012377:Rodentia; D000086965:Viral Zoonoses
Scientific reports
2,020
Lower limb biomechanics during gait do not return to normal following total hip arthroplasty.
Although total hip arthroplasty (THA) is known to be a successful surgical procedure to alleviate hip pain and to improve health-related quality of life, these outcome measures in THA patients do not reach those of the general population. As a result, several investigators have assessed THA patients' gait mechanics, bu...
10.1016/j.gaitpost.2010.05.007
20,541,940
D000368:Aged; D000704:Analysis of Variance; D000843:Ankle Joint; D019644:Arthroplasty, Replacement, Hip; D001696:Biomechanical Phenomena; D016022:Case-Control Studies; D005260:Female; D005684:Gait; D006621:Hip Joint; D006801:Humans; D021621:Imaging, Three-Dimensional; D007719:Knee Joint; D007866:Leg; D008297:Male; D008...
Gait & posture
2,010
Feasibility and impact of whole-body high-intensity interval training in patients with stable coronary artery disease: a randomised controlled trial.
Exercise training reduces cardiovascular mortality and improves quality of life in CAD patients. We investigated the feasibility and impact of 12 weeks of low-volume high-intensity interval training (HIIT) in CAD-patients. Patients with stable CAD were randomized 1:1 to supervised HIIT or standard care. HIIT sessions w...
10.1038/s41598-022-21655-w
36,241,898
D003324:Coronary Artery Disease; D005240:Feasibility Studies; D000072696:High-Intensity Interval Training; D006801:Humans; D010100:Oxygen; D011788:Quality of Life
Scientific reports
2,022
D010100:Oxygen
Probiotics as Prophylaxis for Postoperative Infections of Under-five Children Following Gastrointestinal Surgery.
Purpose Evaluation of the efficacy of use of probiotics as prophylaxis for postoperative wound infection in under-five children following gastrointestinal surgery. Materials and Methods This randomized control trial was conducted over a period of 2 years in the pediatric surgery units of a tertiary level hospital in ...
10.4103/jiaps.jiaps_166_21
36,530,805
Journal of Indian Association of Pediatric Surgeons
2,022
Integration of conventional quantitative and phospho-proteomics reveals new elements in activated Jurkat T-cell receptor pathway maintenance.
Recent years have seen a constant development of tools for the global assessment of phosphoproteins. Here, we outline a concept for integrating approaches for quantitative proteomics and phosphoproteomics. The strategy was applied to the analysis of changes in signalling and protein synthesis occurring after activation...
10.1002/pmic.201400119
25,348,772
D002853:Chromatography, Liquid; D006801:Humans; D019169:Jurkat Cells; D013058:Mass Spectrometry; D053858:Metabolic Networks and Pathways; D010748:Phosphopeptides; D010750:Phosphoproteins; D014176:Protein Biosynthesis; D011494:Protein Kinases; D040901:Proteomics; D011948:Receptors, Antigen, T-Cell; D015398:Signal Transd...
Proteomics
2,015
D010748:Phosphopeptides; D010750:Phosphoproteins; D011948:Receptors, Antigen, T-Cell; D011494:Protein Kinases
[Effect of salmon calcitonin on postoperative humeral head replacement in elderly patients].
OBJECTIVE To observe the effect of anti-osteoporosis drugs on the curative effect of femoral head replacement in the elderly patients with proximal humerus fracture. METHODS From November 2012 to June 2016, 38 patients with proximal humeral fractures received humeral head replacement were divided into the treatment g...
10.3969/j.issn.1003-0034.2019.02.008
30,884,929
D000368:Aged; D002116:Calcitonin; D005593:Fracture Fixation, Internal; D006801:Humans; D058430:Humeral Head; D011184:Postoperative Period; D012784:Shoulder Fractures; D012785:Shoulder Joint; D016896:Treatment Outcome
Zhongguo gu shang = China journal of orthopaedics and traumatology
2,019
C028815:salmon calcitonin; D002116:Calcitonin
Obesity modulate serum hepcidin and treatment outcome of iron deficiency anemia in children: a case control study.
BACKGROUND Recently, hepcidin expression in adipose tissue has been described and shown to be increased in patients with severe obesity. We tried to assess the effect of obesity on hepcidin serum levels and treatment outcome of iron deficiency anemia in children. METHODS This was a case control study included 70 chil...
10.1186/1824-7288-37-34
21,771,327
D018798:Anemia, Iron-Deficiency; D023181:Antimicrobial Cationic Peptides; D015415:Biomarkers; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D064451:Hepcidins; D006801:Humans; D007501:Iron; D058085:Iron Compounds; D008297:Male; D009765:Obesity; D011446:Prospective Studies; D016896:Treatment Outcome
Italian journal of pediatrics
2,011
D023181:Antimicrobial Cationic Peptides; D015415:Biomarkers; C578702:HAMP protein, human; D064451:Hepcidins; D058085:Iron Compounds; D007501:Iron
Increase in detectable opportunistic bacteria in the oral cavity of orthodontic patients.
OBJECTIVES This study was performed to detect the opportunistic bacteria and fungi from the oral cavities of orthodontic patients and examine the ability of the organisms to adhere to saliva-coated metallic brackets. METHODS Opportunistic bacteria and fungi were isolated from 58 patients (orthodontic group: 42; non-o...
10.1111/j.1601-5037.2008.00333.x
19,416,094
D000202:Activator Appliances; D000293:Adolescent; D000328:Adult; D001422:Bacterial Adhesion; D002176:Candida albicans; D003722:Dental Alloys; D003773:Dental Plaque; D003777:Dental Prophylaxis; D016972:Enterobacter cloacae; D005658:Fungi; D006090:Gram-Negative Bacteria; D006094:Gram-Positive Bacteria; D006801:Humans; D0...
International journal of dental hygiene
2,009
D003722:Dental Alloys
Anticancer activities and mechanisms of bisdioxopiperazine compounds probimane and MST-16.
Bisdioxopiperazine compounds, including ICRF-154 and razoxane (ICRF-159, Raz), are anticancer agents developed in the UK specifically targeting tumor metastases. Further two bisdioxopiperazine derivatives, probimane (Pro) and MST-16, have been synthesized at the Shanghai Institute of Materia Medica, Chinese Academy of ...
10.2174/1871520611009010078
19,845,502
D000818:Animals; D000970:Antineoplastic Agents; D002453:Cell Cycle; D045744:Cell Line, Tumor; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D010879:Piperazines; D011929:Razoxane
Anti-cancer agents in medicinal chemistry
2,010
D000970:Antineoplastic Agents; D010879:Piperazines; C055262:probimane; D011929:Razoxane; C057773:sobuzoxane
Methanol, Paracetamol Toxicities and Acute Blindness.
Methanol toxicity remains a common problem in developing countries including Saudi Arabia. However, it is much less available than other toxins; thus, clinical suspicion and correlation play pivotal roles in diagnosis. On the other hand, paracetamol is widely available and overdose/toxicity is highly suspected especial...
10.7759/cureus.8179
32,566,420
Cureus
2,020
Clinical effectiveness of kinesiological taping on pain and pain-free shoulder range of motion in patients with shoulder impingement syndrome: a randomized, double blinded, placebo-controlled trial.
BACKGROUND Kinesiological taping (KT) is commonly used to improve symptoms associated with musculoskeletal disorders. However, review of the literature revealed minimal evidence to support the use of KT in treatment of shoulder disorders and controversy exists regarding the effect of KT in patients with shoulder imping...
24,377,066
International journal of sports physical therapy
2,013
Positive and Negative Consequences of Making Coffee among Breakfast Related Irrelevant Objects: Evidence from MCI, Dementia, and Healthy Ageing.
OBJECTIVES Previous studies have reported impairments in activities of daily living (ADL) performance in the presence of irrelevant but physically/functionally related objects in dementia patients. The aim of the present study was to increase our knowledge about the impact of the presence of contextually related non-ta...
10.1017/S135561771700025X
28,494,820
D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D060825:Cognitive Dysfunction; D003704:Dementia; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011597:Psychomotor Performance
Journal of the International Neuropsychological Society : JINS
2,017
Infective endocarditis in pregnancy from 2009 to 2019: the consequences of injection drug use.
BACKGROUND Endocarditis during pregnancy carries a maternal mortality of up to 30%, but prior publications do not reflect the current opioid epidemic. CASE PRESENTATIONS We reviewed our institution's infective endocarditis registry from 2009 to 2019 and identified 19 females with endocarditis during pregnancy in orde...
10.1080/23744235.2021.1912821
33,905,273
D004696:Endocarditis; D004697:Endocarditis, Bacterial; D005260:Female; D006801:Humans; D004364:Pharmaceutical Preparations; D011247:Pregnancy; D015819:Substance Abuse, Intravenous; D014261:Tricuspid Valve
Infectious diseases (London, England)
2,021
D004364:Pharmaceutical Preparations
Synthesis of an inhibitor of human immunodeficiency virus infection.
Anti-HIV effects of lentinan sulfate were investigated by using an HTLV-I-carrying cell line, MT-4, in vitro. Lentinan, a fungal branched (1----3)-beta-D-glucan, was sulfated to various degrees by means of two kinds of procedures using piperidine N-sulfonic acid in dimethyl sulfoxide or chlorosulfonic acid in pyridine....
10.1111/j.1349-7006.1989.tb02272.x
2,498,253
D000925:Anticoagulants; D000998:Antiviral Agents; D002455:Cell Division; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D005455:Fluorescent Antibody Technique; D006678:HIV; D015488:HIV Antigens; D015368:Human T-lymphotropic virus 1; D006801:Humans; D007912:Lentinan; D011134:Polysaccharides; D013455:Sulfur
Japanese journal of cancer research : Gann
1,989
D000925:Anticoagulants; D000998:Antiviral Agents; D015488:HIV Antigens; D011134:Polysaccharides; C059822:lentinan sulfate; D007912:Lentinan; D013455:Sulfur
Genotyping of Coxiella burnetii in sheep and goat abortion samples.
BACKGROUND Q fever, caused by Coxiella burnetii, is a zoonosis that presents a worldwide distribution and affects both humans and animals. The route of dispersal of the pathogen by ruminants into the environment usually involves stages of abortion and parturition, nevertheless the agent can, also, be detected in other ...
10.1186/s12866-018-1353-y
30,514,233
D000034:Abortion, Veterinary; D000818:Animals; D002417:Cattle; D016997:Coxiella burnetii; D014644:Genetic Variation; D005838:Genotype; D015511:Goat Diseases; D006041:Goats; D006115:Greece; D010802:Phylogeny; D011778:Q Fever; D012756:Sheep; D012757:Sheep Diseases; D020080:Tandem Repeat Sequences
BMC microbiology
2,018
High-flow arteriovenous malformations of the mandible and the maxilla: report of 2 cases.
Arteriovenous malformations (AVMs) are rare vascular lesions that can be life-threatening due to potential massive hemorrhage. AVMs can be subdivided according to the type of vessel involved (capillary, venous, and arterial) and can be categorized, according to hemodynamic features, into high-flow and low-flow lesions....
21,070,715
D000792:Angiography; D001165:Arteriovenous Malformations; D002648:Child; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008336:Mandibular Diseases; D008439:Maxillary Diseases; D006472:Oral Hemorrhage; D014057:Tomography, X-Ray Computed
Pediatric dentistry
2,010
Serological markers of hepatitis A, B and C in first year student nurses.
OBJECTIVE To know the prevalence of serological markers of hepatitis A, B and C virus in first year student nurses. SETTING A transversal study of prevalence. SUBJECTS AND METHODS 81 first year student nurses, mean age 20.6 years (18-37, S.D. 3.8), with demographic, epidemiologic and clinical variables, performing ...
9,741,205
D015415:Biomarkers; D005260:Female; D006518:Hepatitis Viruses; D006525:Hepatitis, Viral, Human; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional; D015995:Prevalence; D013030:Spain; D013338:Students, Nursing
Revista espanola de enfermedades digestivas
1,998
D015415:Biomarkers
[Detection of S-gene mutation strain in vertical transmission of HBV and its significance].
OBJECTIVE To study S-gene mutation of hepatitis B virus (HBV) in its vertical transmission and its significance. METHODS Nucleotides of S-gene NT451-660 of HBV were sequenced with dideoxy end termination technique in four female and six male carriers without HBV markers in their spouses and in their intrauterine infe...
10,682,495
D000328:Adult; D002353:Carrier State; D005260:Female; D014644:Genetic Variation; D006509:Hepatitis B; D006515:Hepatitis B virus; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D009154:Mutation
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
1,999
New Insights in Anorexia Nervosa.
Anorexia nervosa (AN) is classically defined as a condition in which an abnormally low body weight is associated with an intense fear of gaining weight and distorted cognitions regarding weight, shape, and drive for thinness. This article reviews recent evidences from physiology, genetics, epigenetics, and brain imagin...
10.3389/fnins.2016.00256
27,445,651
Frontiers in neuroscience
2,016
Cleavage of the Interleukin-11 receptor induces processing of its C-terminal fragments by the gamma-secretase and the proteasome.
The cytokine Interleukin-11 (IL-11) signals through the membrane-bound IL-11 receptor (IL-11R), which is expressed in a cell-type specific manner. We have recently shown that the metalloprotease ADAM10 can cleave the IL-11R. The liberated soluble IL-11R (sIL-11R) ectodomain can bind its ligand, and the resulting IL-11/...
10.1016/j.bbrc.2017.07.106
28,735,867
D000072197:ADAM10 Protein; D053829:Amyloid Precursor Protein Secretases; D000818:Animals; D045744:Cell Line, Tumor; D002462:Cell Membrane; D015870:Gene Expression; D017370:Interleukin-11; D008024:Ligands; D008565:Membrane Proteins; D051379:Mice; D010446:Peptide Fragments; D054448:Precursor Cells, B-Lymphoid; D046988:Pr...
Biochemical and biophysical research communications
2,017
D017370:Interleukin-11; D008024:Ligands; D008565:Membrane Proteins; D010446:Peptide Fragments; D053702:Receptors, Interleukin-11; D053829:Amyloid Precursor Protein Secretases; D000072197:ADAM10 Protein; C491234:Adam10 protein, mouse; D046988:Proteasome Endopeptidase Complex
Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding.
The integrase protein of human immunodeficiency virus type 1 carries out a set of polynucleotidyl transfer reactions that result in the covalent attachment of the retroviral cDNA to host DNA. We have analyzed the activities of a set of deletion derivatives of the integrase protein. The analysis reveals that a central d...
10.1073/pnas.90.8.3428
8,386,373
D000595:Amino Acid Sequence; D001665:Binding Sites; D003001:Cloning, Molecular; D004254:DNA Nucleotidyltransferases; D004926:Escherichia coli; D015497:HIV-1; D019426:Integrases; D008969:Molecular Sequence Data; D016296:Mutagenesis; D009713:Nucleotidyltransferases; D010446:Peptide Fragments; D011994:Recombinant Proteins...
Proceedings of the National Academy of Sciences of the United States of America
1,993
D010446:Peptide Fragments; D011994:Recombinant Proteins; D004254:DNA Nucleotidyltransferases; D019426:Integrases; D009713:Nucleotidyltransferases; D019895:Transposases; D015032:Zinc
Follicular dynamics throughout the oestrous cycle in sheep. A review.
Whatever the stage of the cycle, follicles of various sizes are apparent on the surface of the ovary of sheep. No evidence of waves of follicular growth at fixed-time intervals has been found during the luteal phase, and growth probably occurs at random until the follicle attains a size of 4 to 7 mm. This shows that fo...
10.1051/rnd:19850101
3,919,431
D000780:Anestrus; D000818:Animals; D003338:Corpus Luteum; D015237:Dinoprost; D004967:Estrogens; D004971:Estrus; D005260:Female; D005640:Follicle Stimulating Hormone; D007986:Luteinizing Hormone; D006080:Ovarian Follicle; D010060:Ovulation; D011247:Pregnancy; D011374:Progesterone; D011460:Prostaglandins F; D012756:Sheep
Reproduction, nutrition, developpement
1,985
D004967:Estrogens; D011460:Prostaglandins F; D011374:Progesterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D015237:Dinoprost
Recent advances in heparin-induced thrombocytopenia.
PURPOSE OF REVIEW Heparin-induced thrombocytopenia (HIT) is a prothrombotic complication of heparin therapy caused by antibodies against platelet factor 4/heparin complexes. Progress in our understanding of HIT has translated to improvements in treatment and patient outcomes. The objective of this review is to examine ...
10.1097/MOH.0b013e3283497ef2
21,730,833
D006493:Heparin; D006801:Humans; D013921:Thrombocytopenia
Current opinion in hematology
2,011
D006493:Heparin
Retroperitoneal Approach for Ureteropelvic Junction Obstruction: Encouraging Preliminary Results With Robot-Assisted Laparoscopic Repair.
Introduction stating the aim of the study: Robot-assisted laparoscopic pyeloplasty (RALP) is gaining acceptance among pediatric urologists. Few studies have evaluated the retroperitoneal approach for RALP. We share our experience from the first 2 years of a multidisciplinary pediatric robotic program in our center. Pat...
10.3389/fped.2019.00209
31,192,176
Frontiers in pediatrics
2,019
The effect of arm sling on balance in patients with hemiplegia.
The aim of this study was to investigate the effect of an arm sling on balance in patients with, hemiplegia following a stroke. Twenty-six patients with hemiplegia (11 men, 15 women) who had, shoulder subluxation were enrolled in the study. Balance was evaluated by the Berg Balance Scale, the, Functional Reach test, an...
10.1016/j.gaitpost.2010.09.008
20,888,770
D000328:Adult; D000368:Aged; D001132:Arm; D001696:Biomechanical Phenomena; D005260:Female; D005684:Gait; D006429:Hemiplegia; D006801:Humans; D008297:Male; D008875:Middle Aged; D004856:Postural Balance; D012783:Shoulder Dislocation; D012785:Shoulder Joint
Gait & posture
2,010
A three-group comparison of acute-onset dizzy, long-term dizzy and non-dizzy older patients in primary care.
BACKGROUND AND AIMS The hypothesis of increased cardiovascular risk contributing to chronic dizziness has been discussed controversially so far. We investigated older patients suffering from acute (<6 months), chronic (≥ 6 months) or no dizziness, in terms of their cardiovascular risk and other impairments. METHODS A...
10.3275/7231
20,802,259
D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases; D003430:Cross-Sectional Studies; D004244:Dizziness; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D011320:Primary Health Care; D012307:Risk Factors
Aging clinical and experimental research
2,011
Bacterial co-infections and antibiotic prescribing practice in adults with COVID-19: experience from a single hospital cluster.
BACKGROUND Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected millions of individuals since December 2019, resulting in significant morbidity and mortality globally. During the 1918 Influenza Pandemic, it was observed that influenza was associat...
10.1177/2049936120978095
33,335,724
Therapeutic advances in infectious disease
2,020
Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies.
A novel series of thiophene and benzodioxole appended thiazolyl-pyrazoline derivatives have been designed, synthesized and evaluated against different bacteria and fungi. The antimicrobial activity of the synthesized compounds were screened using MIC method and were proved synthesized compounds 7o, 7r and 7t to show go...
26,028,159
D000890:Anti-Infective Agents; D052117:Benzodioxoles; D001665:Binding Sites; D027101:DNA Topoisomerase IV; D005658:Fungi; D006090:Gram-Negative Bacteria; D006094:Gram-Positive Bacteria; D008826:Microbial Sensitivity Tests; D008872:Microwaves; D062105:Molecular Docking Simulation; D011485:Protein Binding; D011720:Pyrazo...
Bioorganic & medicinal chemistry letters
2,015
D000890:Anti-Infective Agents; D052117:Benzodioxoles; D011720:Pyrazoles; D013844:Thiazoles; D013876:Thiophenes; D027101:DNA Topoisomerase IV
State anxiety and cardiovascular activity in an academic examination.
Exam is an academic stressor that frequently triggers the affective reaction of anxiety, as well as psychophysiological changes in the autonomic nervous system. Anxiety is a negative affective variable associated with a low level of performance. This study examined the impact of an academic exam on state anxiety (SA) l...
10.1002/pchj.411
33,271,635
D001007:Anxiety; D005260:Female; D006339:Heart Rate; D006801:Humans; D010555:Personality Inventory
PsyCh journal
2,021
Orthostatic Hypotension: A Practical Approach.
Orthostatic hypotension is defined as a decrease in blood pressure of 20 mm Hg or more systolic or 10 mm Hg or more diastolic within three minutes of standing from the supine position or on assuming a head-up position of at least 60 degrees during tilt table testing. Symptoms are due to inadequate physiologic compensat...
35,029,940
D000058:Accidental Falls; D000293:Adolescent; D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002637:Chest Pain; D003920:Diabetes Mellitus; D004032:Diet; D004244:Dizziness; D015103:Droxidopa; D005438:Fludrocortisone; D000082742:Heart Disease Risk Factors; D006339:Heart Rate; D006801:Humans; D007024:Hypotension, O...
American family physician
2,022
D008879:Midodrine; D015103:Droxidopa; D005438:Fludrocortisone
Living with sub-optimal glycaemic control: the experiences of Type 2 diabetes diagnosis and education.
AIM The aim of this study was to explore the experiences of diagnosis and education for people living with Type 2 diabetes who have sub-optimal glycaemic control. BACKGROUND The increasing prevalence of Type 2 diabetes is a global concern. Many people have difficulty maintaining optimal glycaemic control with up to 5...
10.1111/jan.13145
27,624,181
D000328:Adult; D000368:Aged; D001786:Blood Glucose; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic
Journal of advanced nursing
2,017
D001786:Blood Glucose
Ab Interno XEN Gel Stent Implantation in Eyes with Previous Tube Shunt Surgery.
Purpose After tube shunt surgery, many factors may contribute to insufficient filtration over time, prompting further intervention to achieve optimal intraocular pressure (IOP) control. This study explores whether ab interno XEN gel stent implantation could be a viable approach in eyes that need further IOP reduction a...
10.2147/OPTH.S378038
36,204,012
Clinical ophthalmology (Auckland, N.Z.)
2,022
HLA-G genotypes and pregnancy outcome in couples with unexplained recurrent miscarriage.
HLA-G is a non-classical human leukocyte antigen expressed primarily in fetal tissues at the maternal-fetal interface. This expression pattern is unique among HLA genes and suggests that HLA-G may be involved in interactions that are critical in establishing and/or maintaining pregnancy. To evaluate the role of polymor...
10.1093/molehr/7.12.1167
11,719,594
D000026:Abortion, Habitual; D000328:Adult; D000483:Alleles; D005260:Female; D005838:Genotype; D006680:HLA Antigens; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D011247:Pregnancy; D011256:Pregnancy Outcome; D012307:Risk Factors; D01689...
Molecular human reproduction
2,001
D006680:HLA Antigens; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I
Physical characteristics of a clinical d(48.5)+Be neutron therapy beam produced by a superconducting cyclotron.
The Harper Hospital and Wayne State University fast neutron therapy facility is the only one in the world to use a compact superconducting cyclotron and multirod collimator. Neutrons are produced by the interaction of the 48.5-MeV deuteron beam with a thick internal beryllium target and the compact accelerator is gantr...
10.1118/1.597570
8,531,873
D001608:Beryllium; D017357:Cyclotrons; D004867:Equipment Design; D005214:Fast Neutrons; D006801:Humans; D017247:Neutron Capture Therapy; D019047:Phantoms, Imaging; D017785:Photons; D011879:Radiotherapy Dosage; D014867:Water
Medical physics
1,995
D014867:Water; D001608:Beryllium
Bioremediation of selenium-contaminated sediments and water.
Selenium (Se) is a contaminant of agricultural irrigation-drainage water in the western United States, and the cause of wildlife deaths and grotesque deformities. Some approaches in reducing the toxic Se concentrations from contaminated sediments and water have been proposed, but most of these tend to be costly or inef...
10.1002/biof.5520140130
11,568,461
D000383:Agriculture; D001673:Biodegradation, Environmental; D016972:Enterobacter cloacae; D019015:Geologic Sediments; D012643:Selenium; D012989:Soil Pollutants; D014481:United States; D014874:Water Pollutants, Chemical; D018508:Water Purification
BioFactors (Oxford, England)
2,001
D012989:Soil Pollutants; D014874:Water Pollutants, Chemical; D012643:Selenium
Diagnosis and therapy in children with lymphoedema.
INTRODUCTION Lymphoedema (LE) is a disorder characterized by persistent swelling caused by impaired lymphatic drainage because of various aetiologies, including lymphatic injury and congenital functional or anatomical defects. OBJECTIVE Literature review and expert opinion about diagnosis and treatment of LE in child...
10.1258/phleb.2008.008010
19,029,008
D002648:Child; D004322:Drainage; D015444:Exercise; D020022:Genetic Predisposition to Disease; D006801:Humans; D008209:Lymphedema; D016896:Treatment Outcome
Phlebology
2,008
Company size, work-home interference, and well-being of self-employed entrepreneurs.
BACKGROUND The impact of working conditions on the health and well-being of workers of large enterprises has been widely described. This influence has not been studied as extensively in very small and medium-sized enterprises mainly due to methodological difficulties. Smaller organisations nevertheless constitute a rea...
10.1186/s13690-017-0243-3
29,234,494
Archives of public health = Archives belges de sante publique
2,017
Can the Philicity of Radicals Be Influenced by Oriented External Electric Fields?
Herein, the effects of an electric field on radicals are investigated for a set of model radicals with varying complexity. An electric field impacts the intrinsic philicity of a radical, as quantified by the global electrophilicity index, ω. The extent of change in philicity depends on the directionality and strength o...
10.1021/acs.orglett.1c02935
34,652,164
Organic letters
2,022
Successful Management of Critical Acute Respiratory Distress Syndrome following COVID-19 through Extracorporeal Membrane Oxygenation in a Patient with Concurrent Nephrotic Syndrome Relapse.
A 44-year-old man with coronavirus disease 2019 (COVID-19) and nephrotic syndrome relapse was admitted to our intensive-care unit for respiratory failure. Despite receiving mechanical ventilation and immunomodulators, the patient experienced refractory hypoxemia, necessitating venovenous extracorporeal membrane oxygena...
10.2169/internalmedicine.2293-23
37,558,472
D008297:Male; D006801:Humans; D000328:Adult; D000086382:COVID-19; D015199:Extracorporeal Membrane Oxygenation; D009404:Nephrotic Syndrome; D012128:Respiratory Distress Syndrome; D012008:Recurrence
Internal medicine (Tokyo, Japan)
2,023
Information-seeking behaviors of first-semester veterinary students: a preliminary report.
Although emphasis in veterinary education is increasingly being placed on the ability to find, use, and communicate information, studies on the information behaviors of veterinary students or professionals are few. Improved knowledge in this area will provide valuable information for course and curriculum planning and ...
10.3138/jvme.38.1.21
21,805,932
D000328:Adult; D003197:Computer Literacy; D004520:Education, Veterinary; D005260:Female; D006306:Health Surveys; D006801:Humans; D007196:Indiana; D057226:Information Seeking Behavior; D020407:Internet; D007993:Libraries, Medical; D007999:Library Services; D008297:Male; D057386:Search Engine; D013336:Students, Health Oc...
Journal of veterinary medical education
2,011
[Transparency test for plastic containers].
A new sensory test method for judging the transparency of plastics containers for aqueous infusion was developed. The test procedure is as follows: Prepare four different grades of reference suspensions, grade 1 to 4, according to the procedure in ISO/DIS 3826. 4. Take ten empty containers. Fill two containers with the...
2,636,941
D004349:Drug Packaging; D010969:Plastics; D013535:Suspensions
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences
1,989
D010969:Plastics; D013535:Suspensions
Positive correlation between symptoms and circulating motilin, pancreatic polypeptide and gastrin concentrations in functional bowel disorders.
Motilin, pancreatic polypeptide and gastrin blood concentrations in response to drinking water have been studied in 40 patients with functional bowel disease and compared with results in two groups of healthy control subjects. Patients with slow transit constipation and idiopathic megacolon showed impaired motilin rele...
10.1136/gut.26.10.1059
4,054,704
D000328:Adult; D003109:Colonic Diseases, Functional; D003248:Constipation; D003967:Diarrhea; D004326:Drinking; D005260:Female; D005755:Gastrins; D006801:Humans; D007410:Intestinal Diseases; D008297:Male; D008531:Megacolon; D008875:Middle Aged; D009037:Motilin; D010191:Pancreatic Polypeptide; D014867:Water
Gut
1,985
D005755:Gastrins; D014867:Water; D009037:Motilin; D010191:Pancreatic Polypeptide
NLR Is Associated With Geriatric Depression in Chinese Women: A Community-Based Cross-Sectional Study in Eastern China.
In recent years, the prevalence of depression has been increasing, causing a serious global burden of disease. Previous studies have proved that low-grade inflammation is involved in the process of depression. To explore the role of inflammation in the pathogenesis of senile depression, neutrophil to lymphocyte ratio (...
10.3389/fpsyg.2019.02941
31,998,193
Frontiers in psychology
2,019
Pulmonary artery pressure changes during exercise and daily activities in chronic heart failure.
Long-term continuous pulmonary artery pressure monitoring was used to investigate pressure changes during different types of exercise and normal daily activities in patients with chronic heart failure. Nine men (mean age 55 years) with treated chronic heart failure underwent continuous pulmonary artery pressure measure...
10.1016/0735-1097(90)90174-n
2,295,741
D000203:Activities of Daily Living; D015924:Blood Pressure Monitors; D004435:Eating; D015444:Exercise; D005080:Exercise Test; D006333:Heart Failure; D006801:Humans; D008297:Male; D008875:Middle Aged; D011187:Posture; D011669:Pulmonary Wedge Pressure; D014554:Urination
Journal of the American College of Cardiology
1,990
Changes in the Secretory Profile of NSCLC-Associated Fibroblasts after Ablative Radiotherapy: Potential Impact on Angiogenesis and Tumor Growth.
In the context of radiotherapy, collateral effects of ablative doses of ionizing radiation (AIR) on stromal components of tumors remains understudied. In this work, cancer-associated fibroblasts (CAFs) isolated from freshly resected human lung tumors were exposed to AIR (1x 18 Gy) and analyzed for their release of para...
10.1593/tlo.12349
23,418,618
Translational oncology
2,013
Persistent changes in protein synthesis by vagina of ovariectomized mice exposed neonatally to diethylstilbestrol.
Neonatal treatment of female mice with a synthetic estrogen, diethylstilbestrol (DES), results in adenosis, ovary-independent epithelial proliferation and cornification, and downgrowths in the vagina. Protein synthesis was examined in the vagina of 45-day-old, ovariectomized C57BL/Tw mice which had been given 5 daily i...
8,504,214
D000818:Animals; D000831:Animals, Newborn; D004054:Diethylstilbestrol; D005260:Female; D051379:Mice; D008810:Mice, Inbred C57BL; D010052:Ovariectomy; D010053:Ovary; D014176:Protein Biosynthesis; D012741:Sexual Maturation; D013462:Sulfur Radioisotopes; D014621:Vagina
In vivo (Athens, Greece)
1,993
D013462:Sulfur Radioisotopes; D004054:Diethylstilbestrol
Measurements of water vapor isotope ratios with wavelength-scanned cavity ring-down spectroscopy technology: new insights and important caveats for deuterium excess measurements in tropical areas in comparison with isotope-ratio mass spectrometry.
The new infrared laser spectroscopic techniques enable us to measure the isotopic composition (δ(18)O and δ(2)H) of atmospheric water vapor. With the objective of monitoring the isotopic composition of tropical water vapor (West Africa, South America), and to discuss deuterium excess variability (d=δ(2)H - 8δ(18)O) wit...
10.1002/rcm.5252
22,095,494
Rapid communications in mass spectrometry : RCM
2,011
Modeling the charge distribution at metal sites in proteins for molecular dynamics simulations.
Almost half of the proteome of living organisms is constituted of metalloproteins. Unfortunately, the ability of the current generation of molecular dynamics pairwise-additive forcefields to properly describe metal pockets is severely lacking due to the intrinsic difficulty of handling polarization and charge transfer ...
10.1016/j.jsb.2006.10.019
17,188,512
D001665:Binding Sites; D019295:Computational Biology; D003198:Computer Simulation; D008667:Metalloproteins; D008670:Metals; D008958:Models, Molecular; D017510:Protein Folding
Journal of structural biology
2,007
D008667:Metalloproteins; D008670:Metals
Detection and Enumeration of Salmonella enteritidis in Fresh and Stored Eggs Laid by Experimentally Infected Hens.
Laying hens were orally inoculated with a phage type 13a strain of Salmonella enteritidis (SE). Eggs laid by the infected hens were collected daily between the 4th and 14th d postinoculation and randomly allocated into three groups. One group of eggs was sampled on the day of collection, one group was held for 7 d at 7...
10.4315/0362-028X-55.3.152
31,071,840
Journal of food protection
1,992
Required early complement activation in contact sensitivity with generation of local C5-dependent chemotactic activity, and late T cell interferon gamma: a possible initiating role of B cells.
Complement (C) is an important component of innate immunity, and was also shown recently to participate in induction of acquired B cell humoral immunity. In this study, we present evidence that C also participates in acquired T cell immunity. We found that C was involved in early events of the efferent elicitation phas...
10.1084/jem.186.7.1015
9,314,551
D000818:Animals; D000911:Antibodies, Monoclonal; D001402:B-Lymphocytes; D002630:Chemotactic Factors; D002633:Chemotaxis; D003167:Complement Activation; D003182:Complement C5; D003169:Complement Inactivator Proteins; D003877:Dermatitis, Contact; D004546:Elapid Venoms; D005260:Female; D006968:Hypersensitivity, Delayed; D...
The Journal of experimental medicine
1,997
D000911:Antibodies, Monoclonal; D002630:Chemotactic Factors; D003182:Complement C5; D003169:Complement Inactivator Proteins; D004546:Elapid Venoms; D011951:Receptors, Complement; D011994:Recombinant Proteins; C016310:cobra venom factor; C082885:soluble complement inhibitor 1; D007371:Interferon-gamma
Cardiac damage in acute organophosphate poisoning in rats: effects of atropine and pralidoxime.
Anticholinesterase poisoning is an important health problem in our country, and a complete understanding of its underlying mechanisms is essential for the emergency physician. Thus, we aimed to investigate the cardiac biochemical parameters and mortality in dichlorvos-induced poisoning in rats. Rats were randomly divid...
10.1016/j.ajem.2008.01.016
19,371,524
D000208:Acute Disease; D000704:Analysis of Variance; D000818:Animals; D000931:Antidotes; D001285:Atropine; D015415:Biomarkers; D002800:Cholinesterase Inhibitors; D004006:Dichlorvos; D006321:Heart; D007150:Immunohistochemistry; D020287:In Situ Nick-End Labeling; D008297:Male; D009569:Nitric Oxide; D062025:Organophosphat...
The American journal of emergency medicine
2,009
D000931:Antidotes; D015415:Biomarkers; D002800:Cholinesterase Inhibitors; D011220:Pralidoxime Compounds; D009569:Nitric Oxide; D001285:Atropine; D004006:Dichlorvos; C028797:pralidoxime
Application of the Healthy Eating Index-2010 to the hunger relief system.
OBJECTIVE To demonstrate the feasibility of applying the Healthy Eating Index-2010 (HEI-2010) to the hunger relief setting, specifically by assessing the nutritional quality of foods ordered by food shelves (front-line food provider) from food banks (warehouse of foods). DESIGN This Healthy FOOD (Feedback On Ordering...
10.1017/S136898001600118X
27,221,768
D000072001:Diet, Healthy; D005523:Food Supply; D006815:Hunger; D008910:Minnesota; D018673:Nutrition Policy; D009753:Nutritive Value
Public health nutrition
2,016
Seasonal Fluctuations in Sarcophagidae (Diptera: Calyptratae) Assemblages in the Humid Chaco Ecoregion, Argentina.
The seasonal fluctuations of flesh fly (Diptera: Sarcophagidae) assemblages were investigated from March 2015 to February 2016 in five habitat types in the Humid Chaco ecoregion, Chaco Province, Argentina. Three of the habitats were anthropized: an urban area, a cattle farm, and an alfalfa crop; and two were natural: a...
10.1093/jme/tjaa146
32,696,971
D063147:Animal Distribution; D000818:Animals; D001118:Argentina; D058448:Biota; D004777:Environment; D008297:Male; D058493:Sarcophagidae; D012621:Seasons
Journal of medical entomology
2,021
Exposure to neurotoxicants and the development of attention deficit hyperactivity disorder and its related behaviors in childhood.
The purpose of this manuscript is to review the literature to determine evidence of associations between exposure to prenatal and postnatal environmental agents and the development of attention deficit hyperactivity disorder (ADHD) and related behaviors. A review of published research literature was conducted on associ...
24,846,602
D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity; D002648:Child; D002675:Child, Preschool; D003042:Cocaine; D000431:Ethanol; D005260:Female; D003932:Heroin; D006801:Humans; D020264:Lead Poisoning, Nervous System, Childhood; D009498:Neurotoxins; D011247:Pregnancy; D011297:Prenatal Exposure Delay...
Neurotoxicology and teratology
2,014
D009498:Neurotoxins; D000431:Ethanol; D003932:Heroin; D003042:Cocaine
[Community structure characteristics of zooplankton in Yili region of Xinjiang in summer].
In June-July 2006, investigations were made on the zooplankton in the mainstream of Yili River and its three main tributaries (Tekes River, Künes River and Kax River), two reservoirs (Qiapuqihai Reservoir and Jilintai Reservoir), intermittent waters, and ponds in Yili region of Xin-jiang. A total of 217 species belongi...
18,419,090
D000818:Animals; D018533:Biomass; D002681:China; D017753:Ecosystem; D004784:Environmental Monitoring; D056890:Eukaryota; D005618:Fresh Water; D011157:Population Dynamics; D012044:Regression Analysis; D045483:Rivers; D012403:Rotifera; D012621:Seasons; D013045:Species Specificity; D014873:Water Pollutants; D015048:Zoopla...
Ying yong sheng tai xue bao = The journal of applied ecology
2,008
D014873:Water Pollutants
Teratogen-induced cell death in postimplantation mouse embryos: differential tissue sensitivity and hallmarks of apoptosis.
Teratogen-induced cell death is a common event in the pathogenesis associated with tissues destined to be malformed. Although the importance of this cell death is recognized, little information is available concerning the biochemistry of teratogen-induced cell death. We show that three teratogens, hyperthermia, cycloph...
10.1038/sj.cdd.4400390
10,200,514
D000818:Animals; D017209:Apoptosis; D018053:Arsenites; D053148:Caspase 3; D020169:Caspases; D016923:Cell Death; D003520:Cyclophosphamide; D053938:DNA Fragmentation; D047108:Embryonic Development; D004789:Enzyme Activation; D005260:Female; D006257:Head; D006321:Heart; D006361:Heating; D051379:Mice; D009707:Nucleosomes; ...
Cell death and differentiation
1,998
D018053:Arsenites; D009707:Nucleosomes; D017670:Sodium Compounds; D013723:Teratogens; C017947:sodium arsenite; D003520:Cyclophosphamide; D011065:Poly(ADP-ribose) Polymerases; C505409:Casp3 protein, mouse; D053148:Caspase 3; D020169:Caspases
Molecular carpentry: piecing together helices and hairpins in designed peptides.
The design of a peptide that contains two distinct elements of secondary structure, helix and beta-hairpin, is described. Two designed 17-residue peptides: Boc-Val-Ala-Leu-Aib-Val-Ala-Leu-Gly-Gly-Leu-Phe-Val-D-Pro-Gly-Leu-Phe-Val-OMe (I) and Boc-Leu-Aib-Val-Ala-Leu-Aib-Val-Gly-Gly-Leu-Val-Val-D-Pro-Gly-Leu-Val-Val-OMe ...
10.1002/1521-3765(20010216)7:4<840::aid-chem840>3.0.co;2-m
11,288,876
D000595:Amino Acid Sequence; D002942:Circular Dichroism; D008969:Molecular Sequence Data; D019906:Nuclear Magnetic Resonance, Biomolecular; D010455:Peptides; D011487:Protein Conformation
Chemistry (Weinheim an der Bergstrasse, Germany)
2,001
D010455:Peptides
Pseudomonas baetica sp. nov., a fish pathogen isolated from wedge sole, Dicologlossa cuneata (Moreau).
Five Gram-negative bacterial isolates, recovered from an outbreak that occurred in March 2006 in Huelva, Spain, affecting adult diseased cultured wedge sole [Dicologlossa cuneata (Moreau)], were characterized phenotypically and genotypically in order to clarify their taxonomic position. On the basis of 16S rRNA gene se...
10.1099/ijs.0.030601-0
21,642,488
D000818:Animals; D015373:Bacterial Typing Techniques; D004269:DNA, Bacterial; D005227:Fatty Acids; D005393:Fish Diseases; D005412:Flatfishes; D005798:Genes, Bacterial; D008099:Liver; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D010802:Phylogeny; D011549:Pseudomonas; D012336:RNA, Ribosomal, 16S;...
International journal of systematic and evolutionary microbiology
2,012
D004269:DNA, Bacterial; D005227:Fatty Acids; D012336:RNA, Ribosomal, 16S
Economic stress in the workplace: The impact of fear of the crisis on mental health.
BACKGROUND Since 2008, a deep financial crisis, which started in the United States, has widely spread around the world. Scientists expressed their worry about this crisis by pointing out that potential negative health effects can be created by collective fear and panic. OBJECTIVES The main purpose of this cross-secti...
10.3233/WOR-141844
24,594,539
D003430:Cross-Sectional Studies; D057172:Economic Recession; D004651:Employment; D005239:Fear; D005260:Female; D006801:Humans; D008297:Male; D008603:Mental Health; D008960:Models, Psychological; D016272:Occupational Health; D012944:Social Support; D013315:Stress, Psychological; D011795:Surveys and Questionnaires; D0171...
Work (Reading, Mass.)
2,015
Visual short-term memory through the lifespan: Preserved benefits of context and metacognition.
Visual short-term memory (VSTM) ability falls throughout the life span in healthy adults. Using a continuous report task, in a large, population-based sample, we first confirmed that this decline affects the quality and quantity of reported memories as well as knowledge of which item went where. Visual and sensorimotor...
10.1037/pag0000265
30,091,631
D000368:Aged; D000375:Aging; D005260:Female; D006801:Humans; D008136:Longevity; D008297:Male; D008570:Memory, Short-Term; D000067489:Metacognition; D014796:Visual Perception
Psychology and aging
2,018
COVID-19, HIV and key populations: cross-cutting issues and the need for population-specific responses.
INTRODUCTION Key populations at elevated risk to contract or transmit HIV may also be at higher risk of COVID-19 complications and adverse outcomes associated with public health prevention measures. However, the conditions faced by specific populations vary according to social, structural and environmental factors, inc...
10.1002/jia2.25632
33,119,183
D000073640:Betacoronavirus; D000086382:COVID-19; D018352:Coronavirus Infections; D005260:Female; D015658:HIV Infections; D018451:Homosexuality, Male; D006801:Humans; D007182:Income; D008297:Male; D058873:Pandemics; D011024:Pneumonia, Viral; D065129:Pre-Exposure Prophylaxis; D011329:Prisoners; D011634:Public Health; D01...
Journal of the International AIDS Society
2,020
Hypoxia, Serum Starvation, and TNF-α Can Modify the Immunomodulation Potency of Human Adipose-Derived Stem Cells.
INTRODUCTION Adipose-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that are found in adipose tissues, which are easily obtained from liposuction procedures using an enzyme mixture. The adhering cells are then selectively cultivated. ADSCs have great potential in regenerative medicine because they are ple...
10.1007/5584_2021_672
34,739,720
Advances in experimental medicine and biology
2,021
Risk and Resilience Factors for Mental Health among Transgender and Gender Nonconforming (TGNC) Youth: A Systematic Review.
In recent years, there has been a proliferation of research regarding transgender and gender nonconforming (TGNC) people. The stigma and legal discriminations that this population faces have obvious and documented repercussions for mental health. In 2015, the American Psychological Association (APA) published Guideline...
10.1007/s10567-021-00344-6
33,594,611
D000293:Adolescent; D002648:Child; D005783:Gender Identity; D006801:Humans; D008603:Mental Health; D065840:Protective Factors; D012944:Social Support; D063106:Transgender Persons; D055815:Young Adult
Clinical child and family psychology review
2,021
Subjective symptoms of RME patients treated with three different screw activation protocols: a randomised clinical trial.
AIMS The purpose of the present study was to evaluate the subjective symptoms of patients during the active phase of rapid maxillary expansion (RME) treatment, and further, to assess the differences between three different RME activation protocols. MATERIALS AND METHODS The clinical sample consisted of 60 patients (m...
23,304,972
D000293:Adolescent; D002648:Child; D002985:Clinical Protocols; D004244:Dizziness; D005260:Female; D005500:Follow-Up Studies; D006261:Headache; D006801:Humans; D008297:Male; D008310:Malocclusion; D016382:Orthodontic Appliance Design; D010147:Pain Measurement; D010155:Palatal Expansion Technique; D011312:Pressure; D01179...
Australian orthodontic journal
2,012
Pesticide contamination of fish ponds in relation to crop area in a mixed farmland-pond landscape (Dombes area, France).
Pesticides are still widely used by agriculture, leading to the exposure of surface water. This may be the case for fish ponds located in farmland landscapes. To address this issue, the present study investigated the contamination by pesticides of fish ponds located in the mixed agriculture-pond landscape of the Dombes...
10.1007/s11356-022-20492-8
35,513,618
D000081:Acetamides; D000818:Animals; D004784:Environmental Monitoring; D000072480:Farms; D005399:Fishes; D006540:Herbicides; D010573:Pesticide Residues; D010575:Pesticides; D010671:Phenylurea Compounds; D061005:Ponds; D014867:Water; D014874:Water Pollutants, Chemical; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolep...
Environmental science and pollution research international
2,022
D000081:Acetamides; D006540:Herbicides; D010573:Pesticide Residues; D010575:Pesticides; D010671:Phenylurea Compounds; D014874:Water Pollutants, Chemical; D014867:Water; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; C007033:chlortoluron; C051786:metolachlor
Optical coherence tomography and its use in detection of vulnerable plaque.
Acute coronary syndromes and their associated complications related to coronary ischemia continue to be the leading cause of morbidity and mortality in the world. The most commonly encountered pathophysiologic cascade of events resulting in this picture is initiated by formation of a vulnerable plaque. Despite the wide...
10.1007/s11883-006-0051-7
16,510,048
D000818:Animals; D003324:Coronary Artery Disease; D003331:Coronary Vessels; D006801:Humans; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence
Current atherosclerosis reports
2,006
Study of damage to red blood cells exposed to different doses of γ-ray irradiation.
BACKGROUND The aims of this research were to study alterations in the ultrastructure of red blood cells, the changes in concentrations of plasma electrolytes and the killing effect of lymphocytes in samples of blood exposed to different doses of γ-ray irradiation. MATERIALS AND METHODS Blood samples were treated with...
10.2450/2012.0076-11
22,682,338
D000293:Adolescent; D000328:Adult; D002712:Chlorides; D004307:Dose-Response Relationship, Radiation; D004912:Erythrocytes; D053222:Fas Ligand Protein; D005260:Female; D005720:Gamma Rays; D005786:Gene Expression Regulation; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008214:Lymphocytes; D008297:Male; D046529:Mi...
Blood transfusion = Trasfusione del sangue
2,012
D002712:Chlorides; C491901:FAS protein, human; C505661:FASLG protein, human; D053222:Fas Ligand Protein; D019014:fas Receptor; D012964:Sodium; D011188:Potassium
Adjunctive thrombectomy and distal protection in primary percutaneous coronary intervention: impact on microvascular perfusion and outcomes.
A significant proportion of patients with ST-elevation myocardial infarction have persistent impairment of microvascular blood flow despite successful reperfusion of epicardial vessels. Microvascular dysfunction has been associated with larger infarct size, increased predisposition to ventricular arrhythmias, heart fai...
10.1161/CIRCULATIONAHA.108.831453
19,273,732
D015906:Angioplasty, Balloon, Coronary; D003326:Coronary Circulation; D003328:Coronary Thrombosis; D006801:Humans; D008833:Microcirculation; D009203:Myocardial Infarction; D016032:Randomized Controlled Trials as Topic; D017131:Thrombectomy
Circulation
2,009
Surface plasmon resonance for the label-free detection of Alzheimer's β-amyloid peptide aggregation.
Amyloid peptide oligomers and fibrils are studied as targets for therapy and diagnosis of Alzheimer's disease. They are usually detected by amyloid incubation, but such method is necessarily associated with Aβ1-42 depletion and dye binding or conjugation, which have a complex influence on fibril growth, provide informa...
10.1007/s00216-015-9172-6
26,558,762
D000544:Alzheimer Disease; D016229:Amyloid beta-Peptides; D006801:Humans; D020349:Surface Plasmon Resonance
Analytical and bioanalytical chemistry
2,016
D016229:Amyloid beta-Peptides
The total peroxyl radical trapping potential in serum - an assay to define the stage of atherosclerosis.
Lipid peroxides were identified among the factors that contribute to the atherosclerotic plaque formation in the arterial wall. We hypothesised that a correlation may exist between the content of antioxidant constituents in the serum and the gravity of atherosclerosis. To this purpose, we have determined the serum tota...
10.1111/j.1582-4934.2001.tb00162.x
12,067,487
D000818:Animals; D000975:Antioxidants; D001021:Aortic Valve; D002784:Cholesterol; D003324:Coronary Artery Disease; D006224:Cricetinae; D003924:Diabetes Mellitus, Type 2; D006801:Humans; D008054:Lipid Peroxides; D008297:Male; D008647:Mesocricetus; D051379:Mice; D009130:Muscle, Smooth; D010545:Peroxides; D011817:Rabbits;...
Journal of cellular and molecular medicine
2,001
D000975:Antioxidants; D008054:Lipid Peroxides; D010545:Peroxides; D014280:Triglycerides; C049375:perhydroxyl radical; D002784:Cholesterol
Integrated Smartphone-App-Chip System for On-Site Parts-Per-Billion-Level Colorimetric Quantitation of Aflatoxins.
We demonstrate herein an integrated, smartphone-app-chip (SPAC) system for on-site quantitation of food toxins, as demonstrated with aflatoxin B1 (AFB1), at parts-per-billion (ppb) level in food products. The detection is based on an indirect competitive immunoassay fabricated on a transparent plastic chip with the ass...
10.1021/acs.analchem.7b01379
28,719,742
D016604:Aflatoxin B1; D000906:Antibodies; D003124:Colorimetry; D005504:Food Analysis; D007118:Immunoassay; D056656:Lab-On-A-Chip Devices; D057230:Limit of Detection; D044085:Microfluidics; D066330:Printing, Three-Dimensional; D000068997:Smartphone
Analytical chemistry
2,017
D000906:Antibodies; D016604:Aflatoxin B1
Late preterm birth: a new nursing issue.
Late preterm infants are those born between 34 and 36 6/7 completed weeks' gestation. In the last decade, late preterm infants have become the fastest growing subset of preterm infants and now account for 74% of all preterm births. They are at greater risk for feeding problems, dehydration, hypothermia, jaundice, and h...
10.1097/01.NMC.0000334895.91720.5d
18,758,331
D005544:Forecasting; D005865:Gestational Age; D006301:Health Services Needs and Demand; D006801:Humans; D051556:Hyperbilirubinemia, Neonatal; D007035:Hypothermia; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases; D015931:Intensive Care, Neonatal; D007902:Length of Stay; D017283:Neonatal Nursing; D024802:Nur...
MCN. The American journal of maternal child nursing
2,008
PGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells.
Ischemia/reperfusion injury triggers acute kidney injury (AKI) by aggravating oxidative stress mediated mitochondria dysfunction. The peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α) is a master player that regulates mitochondrial biogenesis and the antioxidant response. We postulated that PGC-1...
10.1038/s41598-017-04593-w
28,659,586
D000818:Animals; D000975:Antioxidants; D017209:Apoptosis; D002460:Cell Line; D015870:Gene Expression; D005786:Gene Expression Regulation; D000071679:Glycogen Synthase Kinase 3 beta; D006861:Hydrogen Peroxide; D007674:Kidney Diseases; D008297:Male; D051379:Mice; D051267:NF-E2-Related Factor 2; D000071248:Peroxisome Prol...
Scientific reports
2,017
D000975:Antioxidants; D051267:NF-E2-Related Factor 2; C495636:Nfe2l2 protein, mouse; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; C485290:Ppargc1a protein, mouse; D034741:RNA, Small Interfering; D017382:Reactive Oxygen Species; D006861:Hydrogen Peroxide; D000071679:Glycogen Synthase ...