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Preparation and quality evaluation of potato steamed bread with wheat gluten. | The present study aimed to study the preparation and quality evaluation of potato steamed bread by using potato flour, wheat flour, and gluten at the presence of yeast and inorganic additives. As the rheological properties of the potato-wheat formulated flour negatively related to the potato flour, the potato-wheat for... | 10.1002/fsn3.1600 | 32,884,680 | Food science & nutrition | 2,020 | ||
Automated ECG classification based on 1D deep learning network. | The standard 12-lead electrocardiogram (ECG) records the heart's electrical activity from electrodes on the skin, and is widely used in screening and diagnosis of the cardiac conditions due to its low price and non-invasive characteristics. Manual examination of ECGs requires professional medical skills, and is strenuo... | 10.1016/j.ymeth.2021.04.021 | 33,930,574 | D000465:Algorithms; D001145:Arrhythmias, Cardiac; D000077321:Deep Learning; D004562:Electrocardiography; D004566:Electrodes; D006801:Humans; D016571:Neural Networks, Computer | Methods (San Diego, Calif.) | 2,022 | |
Why the genome does not congeal. | Since the genes in any given organism have evolved together to produce an adaptive phenotype, one might expect that rearrangement by chromosomal recombination would be maladaptive and thus wiped out by natural selection. This article reviews various theories that explain why, on the contrary, recombination is almost un... | 10.1038/268693a0 | 331,119 | D000483:Alleles; D000818:Animals; D002843:Chromatin; D003434:Crossing Over, Genetic; D004777:Environment; D008954:Models, Biological; D009154:Mutation; D011110:Polymorphism, Genetic; D011995:Recombination, Genetic; D012641:Selection, Genetic; D012801:Sibling Relations | Nature | 1,977 | D002843:Chromatin |
Lipid-liquid crystals for 2 months controlled risperidone release: In-vitro evaluation and pharmacokinetics in rabbits. | In this study, a drug delivery system based on lipid liquid crystal (LLC) was developed for the long-term delivery of risperidone to improve psychological treatment. Optimal LLC formulation was achieved based on maximum release after 60 days with different ratios of phosphatidylcholine (PC) to sorbitol monooleate (PC: ... | 10.1016/j.ijpharm.2022.121649 | 35,278,600 | D000818:Animals; D065546:Drug Liberation; D008055:Lipids; D050866:Liquid Crystals; D011136:Polysorbates; D011817:Rabbits; D018967:Risperidone | International journal of pharmaceutics | 2,022 | D008055:Lipids; D011136:Polysorbates; D018967:Risperidone |
The alliance to reduce disparities in diabetes: infusing policy and system change with local experience. | This supplement provides a comprehensive and in-depth examination of proven clinical-community health strategies employed by the Alliance to Reduce Disparities in Diabetes, across five sites located in diverse geographic regions of the United States, including a tribal community. Alliance projects in these communities ... | 10.1177/1524839914545784 | 25,359,252 | D019058:Community Networks; D003695:Delivery of Health Care; D003924:Diabetes Mellitus, Type 2; D006291:Health Policy; D054625:Healthcare Disparities; D006801:Humans; D014481:United States; D035862:Vulnerable Populations | Health promotion practice | 2,014 | |
Changes in Knee Osteoarthritis, Symptoms, and Function After Anterior Cruciate Ligament Reconstruction: A 20-Year Prospective Follow-up Study. | BACKGROUND
Progression of tibiofemoral (TF) and patellofemoral (PF) osteoarthritis (OA) and changes in knee function more than 15 years after anterior cruciate ligament reconstruction (ACLR) are not well understood.
PURPOSE
To examine the progression of knee OA and changes in symptoms and function in isolated and com... | 10.1177/0363546515626539 | 26,912,282 | D000328:Adult; D000070598:Anterior Cruciate Ligament Injuries; D059549:Anterior Cruciate Ligament Reconstruction; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D020370:Osteoarthritis, Knee; D0000710... | The American journal of sports medicine | 2,016 | |
Measurements of distances related to the mandibular canal in radiographs. | Before implant surgery in the mandibular side segment, it is of utmost interest to locate the mandibular canal in radiographs to avoid interference with the neurovascular bundle during surgery. Six mandibular specimens were radiographically examined with 2 panoramic and 3 tomographic techniques. The distances between t... | 10.1034/j.1600-0501.1995.060205.x | 7,578,787 | D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008334:Mandible; D008340:Mandibular Nerve; D008875:Middle Aged; D015588:Observer Variation; D010347:Patient Care Planning; D011862:Radiography, Panoramic; D015203:Reproducibility of Results; D014056:Tomography, X-Ray; D014057:Tomography, X-Ray Computed | Clinical oral implants research | 1,995 | |
Strategic Design and Functionalization of an Amine-Decorated Luminescent Metal Organic Framework for Selective Gas/Vapor Sorption and Nanomolar Sensing of 2,4,6-Trinitrophenol in Water. | On the basis of the strategic design of a triazine-based dicarboxylate ligand with two primary amino groups and one secondary amino group, an amine-functionalized autofluorescent and polar three-dimensional metal organic framework (MOF) {[Cd(ATAIA)]·4H2O} n (1), where H2ATAIA = 5-((4,6-diamino-1,3,5-triazin-2-yl)amino)... | 10.1021/acsami.8b06339 | 29,957,936 | ACS applied materials & interfaces | 2,018 | ||
Challenges in systematic reviews: synthesis of topics related to the delivery, organization, and financing of health care. | Some important health policy topics, such as those related to the delivery, organization, and financing of health care, present substantial challenges to established methods for evidence synthesis. For example, such reviews may ask: What is the effect of for-profit versus not-for-profit delivery of care on patient outc... | 10.7326/0003-4819-142-12_part_2-200506211-00005 | 15,968,030 | D003661:Decision Support Techniques; D003695:Delivery of Health Care; D019317:Evidence-Based Medicine; D006291:Health Policy; D017146:Models, Organizational; D012196:Review Literature as Topic | Annals of internal medicine | 2,005 | |
Evaluation of Length of Stay, Care Volume, In-Hospital Mortality, and Emergency Readmission Rate Associated With Use of Diagnosis-Related Groups for Internal Resource Allocation in Public Hospitals in Hong Kong. | Importance
Hong Kong's internal resource allocation system for public inpatient care changed from a global budget system to one based on diagnosis-related groups (DRGs) in 2009 and returned to a global budget system in 2012. Changes in patient and hospital outcomes associated with moving from a DRG-based system to a gl... | 10.1001/jamanetworkopen.2021.45685 | 35,119,464 | D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D004632:Emergency Medical Services; D005260:Female; D006723:Hong Kong; D017052:Hospital Mortality; D006779:Hospitals, Public; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010359:Patient Readmission; D040841:Resource... | JAMA network open | 2,022 | |
Comparison of different echocardiographic methods with radionuclide imaging for measuring left ventricular ejection fraction during acute myocardial infarction treated by thrombolytic therapy. | The aim of this study was to: (1) compare the usefulness, in clinical practice, of different echocardiographic methods of left ventricular (LV) function determination in patients with a recent thrombolytic-treated acute myocardial infarction (AMI); (2) compare these measurements with the reference method radionuclide i... | 10.1016/s0002-9149(97)00964-8 | 9,514,446 | D000368:Aged; D017023:Coronary Angiography; D004452:Echocardiography; D005260:Female; D015637:Gated Blood-Pool Imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D013318:Stroke Volume; D015912:Thrombolytic Therapy; D016277:Ventricular Function, Left | The American journal of cardiology | 1,998 | |
[Depression in chronic hemodialysis patients: report of 106 cases]. | BACKGROUND
Depression is the most common psychiatric disorder in chronic hemodialysis patients and is associated with mortality.
AIM
To evaluate the prevalence of the depression in patients undergoing chronic hemodialysis, and to identify the correlated factors.
METHODS
The study population included 106 patients on... | 21,308,624 | D000328:Adult; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D003863:Depression; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D006435:Renal Dialysis | La Tunisie medicale | 2,011 | ||
Prevalence of faecal incontinence in adults aged 30 years or more in general population. | OBJECTIVE
The aim of this study was to estimate the prevalence of and factors associated with faecal incontinence in a Finnish population.
METHOD
A population-based age-stratified random sample of 8000 people aged 30-81 years from a large city was obtained from the national population registry. A postal questionnaire... | 10.1111/j.1463-1318.2009.01878.x | 19,486,087 | D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D005242:Fecal Incontinence; D005260:Female; D005387:Finland; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland | 2,010 | |
Development of the left-right axis. | Left-right is not an axis in the conventional sense but rather two mirror-image proximodistal axes, upon which a quantal piece of positional information (leftness or rightness) is superimposed for laterally asymmetric organ development. We are attempting to establish the stages at which left-right is specified and dete... | 10.1002/9780470514221.ch9 | 1,516,466 | D000818:Animals; D046508:Culture Techniques; D005314:Embryonic and Fetal Development; D005260:Female; D007839:Functional Laterality; D008297:Male; D051379:Mice; D012744:Sex Ratio | Ciba Foundation symposium | 1,992 | |
Reliable recognition of DNA methylation using bioanalysis of hybridization on the surface of Ag/GQD nanocomposite stabilized on poly (β-cyclodextrin): A new platform for DNA damage studies using genosensor technology. | Due to the role of DNA methylation in causing cancer in the present study, an innovative and inexpensive method was designed for the sensitive detection of DNA methylation. The silver-graphene quantum dots (Ag/GQDs) nano ink with high electrical conductivity was used as a substrate for genosensor fabrication toward ide... | 10.1002/jmr.2945 | 34,904,757 | D015374:Biosensing Techniques; D004249:DNA Damage; D019175:DNA Methylation; D055664:Electrochemical Techniques; D006108:Graphite; D006801:Humans; D053761:Nanocomposites; D013672:Technology; D047392:beta-Cyclodextrins | Journal of molecular recognition : JMR | 2,022 | D047392:beta-Cyclodextrins; D006108:Graphite |
The Swiss lithoclast: an ideal intracorporeal lithotripter. | We report our early experience with a new device for endoscopic stone disintegration: the Swiss lithoclast. This device was used to treat 200 patients with stones in kidney, ureter, and bladder. Its effectiveness was 100% when the stone could be approached irrespective of size or composition, and no complication was en... | 10.1159/000282740 | 7,571,177 | D000293:Adolescent; D000328:Adult; D000368:Aged; D004724:Endoscopy; D005260:Female; D006801:Humans; D008096:Lithotripsy; D008297:Male; D008875:Middle Aged | Urologia internationalis | 1,995 | |
Genomic integrity in the male germ line: evidence in support of the disposable soma hypothesis. | The Big Blue λSelect-cII selection system has been employed along with whole-exome sequencing to examine the susceptibility of the male germ line to mutation in two challenging situations (i) exposure to a chemotherapeutic regime including bleomycin, etoposide and cis-platinum (BEP) and (ii) the ageing process. A 3-wee... | 29,921,625 | D000375:Aging; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols; D053713:Azoospermia; D001761:Bleomycin; D002843:Chromatin; D002945:Cisplatin; D005047:Etoposide; D005260:Female; D005298:Fertility; D016678:Genome; D005854:Germ Cells; D008297:Male; D051379:Mice; D009154:Mutation; D011247:Pregnancy;... | Reproduction (Cambridge, England) | 2,018 | D002843:Chromatin; D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin | |
Steroid hepatopathy in a horse with glucocorticoid-induced hyperadrenocorticism. | Steroid hepatopathy was diagnosed in a horse with glucorticoid-induced hyperadrenocorticism on the basis of anamnesis, serum biochemical data, and histologic findings of hepatic biopsy. Initially, clinical signs of polyuria, polydypsia, and muscular degeneration were seen. The horse developed laminitis during hospitali... | 1,624,345 | D000308:Adrenocortical Hyperfunction; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury; D003937:Diagnosis, Differential; D005534:Foot Diseases; D006724:Hoof and Claw; D006734:Horse Diseases; D006736:Horses; D006943:Hyperglycemia; D007794:Lameness, Animal; D008107:Liver Diseases; D008297:Male; D014221:Tri... | Journal of the American Veterinary Medical Association | 1,992 | D014221:Triamcinolone | |
[Odontogenic cysts of the jaws. A clinicostatistical study]. | In this paper a retrospective clinicostatistical study of 508 cases of odontogenic cysts of the jaws treated at the Department of Oral and Maxillofacial Surgery of the University of Athens during the last ten years 1977-1987 is undertaken, in order to evaluate their frequency and other aspects of clinical and therapeut... | 2,640,746 | D000293:Adolescent; D000328:Adult; D003803:Dentigerous Cyst; D005260:Female; D006801:Humans; D007571:Jaw Diseases; D008297:Male; D009807:Odontogenic Cysts; D011842:Radicular Cyst; D012189:Retrospective Studies | Stomatologia | 1,989 | ||
Blunting of cardioprotective actions of estrogen in female rodent heart linked to altered expression of cardiac tissue chymase and ACE2. | BACKGROUND
Diastolic dysfunction develops in response to hypertension and estrogen (E2) loss and is a forerunner to heart failure (HF) in women. The cardiac renin-angiotensin system (RAS) contributes to diastolic dysfunction, but its role with respect to E2 and blood pressure remain unclear.
METHODS
We compared the e... | 10.1177/1470320317722270 | 28,748,720 | D000085962:Angiotensin-Converting Enzyme 2; D000818:Animals; D001835:Body Weight; D002118:Calcium; D002316:Cardiotonic Agents; D053818:Chymases; D003094:Collagen; D003971:Diastole; D004967:Estrogens; D005260:Female; D005786:Gene Expression Regulation; D006439:Hemodynamics; D009206:Myocardium; D009929:Organ Size; D01005... | Journal of the renin-angiotensin-aldosterone system : JRAAS | 2,017 | D002316:Cardiotonic Agents; D004967:Estrogens; D000090063:Proto-Oncogene Mas; D011518:Proto-Oncogene Proteins; D044140:Receptor, Angiotensin, Type 1; D011960:Receptors, Estrogen; D043562:Receptors, G-Protein-Coupled; D003094:Collagen; D007703:Peptidyl-Dipeptidase A; C000705329:Ace2 protein, rat; D000085962:Angiotensin-... |
Rational Design of pH-Responsive DNA Motifs with General Sequence Compatibility. | Reconfigurable molecular events are key to molecular machines. In response to external cues, molecular machines rearrange/change their structures to perform certain functions. Such machines exist in nature, for example cell surface receptors, and have been artificially engineered. To be able to build sophisticated and ... | 10.1002/anie.201906972 | 31,529,580 | D004247:DNA; D004591:Electrophoresis, Polyacrylamide Gel; D006863:Hydrogen-Ion Concentration; D036103:Nanotechnology; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D059372:Nucleotide Motifs; D013050:Spectrometry, Fluorescence | Angewandte Chemie (International ed. in English) | 2,019 | D004247:DNA |
Prognostic value of spinal cord MRI in multiple sclerosis patients. | Multiple sclerosis [MS] is a common inflammatory, demyelinating and neurodegenerative disease of the central nervous system that affects both the brain and the spinal cord. In clinical practice, spinal cord MRI is performed far less frequently than brain MRI, mainly owing to technical limitations and time constraints. ... | 10.1016/j.neurol.2020.08.002 | 33,069,379 | D001921:Brain; D018450:Disease Progression; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis; D019636:Neurodegenerative Diseases; D011379:Prognosis; D013116:Spinal Cord | Revue neurologique | 2,021 | |
Intrinsic STAT4 Expression Controls Effector CD4 T Cell Migration and Th17 Pathogenicity. | Effector CD4 T cells are central to the development of autoimmune chronic inflammatory diseases, yet factors that mediate pathogenicity remain ill-defined. Single-nucleotide polymorphisms in the human STAT4 locus are associated with susceptibility to multiple autoimmune disorders, and Stat4 is linked to the pathogenic ... | 10.4049/jimmunol.2200606 | 37,093,664 | D006801:Humans; D051379:Mice; D000818:Animals; D015496:CD4-Positive T-Lymphocytes; D058504:Th17 Cells; D018417:Th1 Cells; D014774:Virulence; D007249:Inflammation; D002454:Cell Differentiation; D004681:Encephalomyelitis, Autoimmune, Experimental; D050797:STAT4 Transcription Factor | Journal of immunology (Baltimore, Md. : 1950) | 2,023 | C494090:STAT4 protein, human; D050797:STAT4 Transcription Factor; C494091:Stat4 protein, mouse |
Novel octanuclear copper(I) metallomacrocycles and their transformation into hexanuclear 2-dimensional grids of copper(i) coordination polymers containing cyclodiphosphazanes, [(micro-NtBuP)2(NC4H8X)2] (X = NMe, O). | Novel octanuclear copper(I) macrocyclic complexes and hexanuclear 2-dimensional grid-like polymers containing [P(micro-NR)](2) scaffold in which the anionic moieties are trapped inside the cationic macrocyclic cavities are reported. | 10.1039/b804311f | 18,560,657 | Dalton transactions (Cambridge, England : 2003) | 2,008 | ||
Antioxidant enzymes and lipid peroxidation in endometrium of patients with polyps, myoma, hyperplasia and adenocarcinoma. | BACKGROUND
Oxidative stress and impaired antioxidant system have been proposed as a potential factors involved in the pathophysiology of diverse disease states, including carcinogenesis. In this study, we explored the lipid peroxidation levels and antioxidant enzyme activities in women diagnosed with different forms of... | 10.1186/1477-7827-7-149 | 20,030,853 | D000230:Adenocarcinoma; D000328:Adult; D000975:Antioxidants; D002374:Catalase; D016889:Endometrial Neoplasms; D004717:Endometrium; D005260:Female; D005979:Glutathione Peroxidase; D005980:Glutathione Reductase; D006801:Humans; D006965:Hyperplasia; D066298:In Vitro Techniques; D015227:Lipid Peroxidation; D008054:Lipid Pe... | Reproductive biology and endocrinology : RB&E | 2,009 | D000975:Antioxidants; D008054:Lipid Peroxides; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase |
SOHO State of the Art Updates and Next Questions | Novel Approaches to Pediatric T-cell ALL and T-Lymphoblastic Lymphoma. | While outcomes for children with T-cell acute lymphoblastic leukemia (T-ALL) and T-lymphoblastic lymphoma (T-LL) have improved significantly with contemporary therapy, outcomes for patients with relapsed or refractory (r/r) disease remain dismal. Improved risk stratification and the incorporation of novel therapeutics ... | 10.1016/j.clml.2022.07.010 | 35,941,070 | D000069286:Bortezomib; D002648:Child; D006801:Humans; D016219:Immunotherapy, Adoptive; D008228:Lymphoma, Non-Hodgkin; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; D000076962:Receptors, Chimeric Antigen; D013601:T-Lymphocytes | Clinical lymphoma, myeloma & leukemia | 2,022 | D000076962:Receptors, Chimeric Antigen; D000069286:Bortezomib |
Relapse of medically treated insulinoma following the development of thyrotoxicosis: an assessment of potential mechanisms. | Increased thyroid hormone concentrations have been reported to have disparate effects on insulin sensitivity in man. We describe a 72-year-old lady who initially presented with episodic hypoglycemia secondary to an insulinoma that was controlled by diazoxide. She re-presented 12 months later with a recurrence of the hy... | 10.1089/thy.1994.4.73 | 8,054,864 | D000368:Aged; D002096:C-Peptide; D003981:Diazoxide; D005260:Female; D006801:Humans; D007003:Hypoglycemia; D007328:Insulin; D007333:Insulin Resistance; D007340:Insulinoma; D010190:Pancreatic Neoplasms; D011433:Propranolol; D012008:Recurrence; D013971:Thyrotoxicosis | Thyroid : official journal of the American Thyroid Association | 1,994 | D002096:C-Peptide; D007328:Insulin; D011433:Propranolol; D003981:Diazoxide |
A non-A non-B hepatitis epidemic in a HB antigen-free haemodialysis unit. Demonstration of serological markers of non-A non-B virus. | One hundred and thirty six patients receiving haemodialysis in a HB antigen-free unit were prospectively studied over a period of 29 months for evidence of hepatitis. Twelve/one hundred and eleven patients who were dialysed in this unit for at least one month developed elevation of ALT which proved to be related to nei... | 6,787,582 | D003428:Cross Infection; D004196:Disease Outbreaks; D005260:Female; D006526:Hepatitis C; D006518:Hepatitis Viruses; D006525:Hepatitis, Viral, Human; D006757:Hospital Units; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis | Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association | 1,980 | ||
Life course weight gain and C-reactive protein levels in young adults: findings from a Brazilian birth cohort. | Rapid weight gain in childhood is associated with increased risk of chronic diseases in adults. C-reactive protein (CRP) is a mediator of atherosclerosis and chronically elevated levels predict cardiovascular outcomes. The effects of life course weight gain on CRP levels are not clear. The 1982 Pelotas (Brazil) birth c... | 10.1002/ajhb.20852 | 19,107,921 | D000293:Adolescent; D001938:Brazil; D002097:C-Reactive Protein; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D015430:Weight Gain; D055815:Young Adult | American journal of human biology : the official journal of the Human Biology Council | 2,009 | D002097:C-Reactive Protein |
How to prevent allopurinol hypersensitivity reactions? | Allopurinol hypersensitivity syndrome (AHS) is a severe and sometimes life-threatening adverse drug reaction. Although AHS is rare, the number of patients with gout requiring allopurinol is high, and there are sufficient overall cases of AHS to warrant consideration of preventive measures. Most cases occur within 8-9 w... | 10.1093/rheumatology/kex422 | 29,272,508 | D000493:Allopurinol; D004305:Dose-Response Relationship, Drug; D004342:Drug Hypersensitivity; D006073:Gout; D006074:Gout Suppressants; D006801:Humans | Rheumatology (Oxford, England) | 2,018 | D006074:Gout Suppressants; D000493:Allopurinol |
Synaptotagmin-7 is overexpressed in hepatocellular carcinoma and regulates hepatocellular carcinoma cell proliferation via Chk1-p53 signaling. | BACKGROUND
Synaptotagmin-7 (Syt-7) is a member of the synaptotagmin (Syt) family, which plays an important role in many physiological and pathological processes. However, to the best of our knowledge, there is no study describing its function in tumors, particularly in hepatocellular carcinoma (HCC). Therefore, in this... | 10.2147/OTT.S143619 | 28,919,777 | OncoTargets and therapy | 2,017 | ||
The distribution of allied dental practitioners in australia: socio-economics and rurality as a driver of better health service accessibility. | OBJECTIVES
Analysis of the distribution of allied dental practitioners relative to the socio-economic profile of the population, to develop a baseline of employment demographics at a time of proposed deregulation of practicing restrictions.
METHODS
A database of allied dental practitioners (ADP - oral health therapis... | 10.1111/adj.12679 | 30,676,647 | D001315:Australia; D003752:Dental Health Services; D006297:Health Services Accessibility; D006301:Health Services Needs and Demand; D006801:Humans; D012423:Rural Health; D019035:Rural Health Services; D012959:Socioeconomic Factors; D013021:South Australia; D035862:Vulnerable Populations; D014904:Western Australia | Australian dental journal | 2,019 | |
[Proposal for the introduction of an energy feed evaluation system based on unitary parameters and principles for all farm animals. 3. Energy feed evaluation for fowls]. | The energy availability from the feedstuffs and the energy requirement of animals are characterized by the metabolizable energy. The metabolizable energy of the feed (feedstuff, ration) is interpreted as potential energy. For comparative analyses within and between animal species with regard to the energetic feed value... | 10.1080/17450399409381800 | 7,668,975 | D000821:Animal Feed; D000818:Animals; D000829:Animals, Domestic; D001835:Body Weight; D002645:Chickens; D004531:Eggs; D004734:Energy Metabolism; D008433:Mathematics; D008460:Meat; D008962:Models, Theoretical; D009751:Nutritional Requirements; D009753:Nutritive Value; D014176:Protein Biosynthesis; D012044:Regression Ana... | Archiv fur Tierernahrung | 1,994 | |
Simultaneous thrombin and plasmin generation capacities in normal and abnormal states of coagulation and fibrinolysis in children and adults. | INTRODUCTION
Thrombin and plasmin are the key enzymes involved in coagulation and fibrinolysis, respectively. Plasma coagulative and fibrinolytic potentials in normal children and adults, and in representative pathologically altered hemostatic states, were evaluated via simultaneous assessment of thrombin and plasmin g... | 10.1016/j.thromres.2010.12.011 | 21,316,746 | D000328:Adult; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D002648:Child; D005341:Fibrinolysin; D005342:Fibrinolysis; D006801:Humans; D013917:Thrombin | Thrombosis research | 2,011 | D013917:Thrombin; D005341:Fibrinolysin |
Molecular aspects of hepatocellular carcinoma. | Hepatocellular carcinoma (HCC) is a highly malignant tumor with a poor prognosis. The success of its established treatment modalities is frequently limited by the advanced stage of the tumor at the time of diagnosis. Therefore, it is important to understand the mechanisms that control its growth behavior. In the presen... | 10.1024/1023-9332.5.3.102 | 10,414,179 | D000818:Animals; D006528:Carcinoma, Hepatocellular; D006801:Humans; D008113:Liver Neoplasms | Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera | 1,999 | |
[Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors]. | Magnetic resonance spectroscopy (MRS) is a method enabling the analysis of the tissue metabolic content. It may offer a more accurate diagnosis of the intracranial tumors than conventional MRI sequences. MRS of normal brain parenchyma displays 4 main metabolites: N-acetyl aspartate (neuronal marker), creatine (cellular... | 12,610,422 | D001224:Aspartic Acid; D015415:Biomarkers; D001922:Brain Abscess; D001932:Brain Neoplasms; D002794:Choline; D003196:Computer Graphics; D003401:Creatine; D003937:Diagnosis, Differential; D005910:Glioma; D006801:Humans; D007294:Inositol; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008579... | Annales de medecine interne | 2,002 | D015415:Biomarkers; D001224:Aspartic Acid; D007294:Inositol; C000179:N-acetylaspartate; D003401:Creatine; D002794:Choline | |
Undernutrition among adult Bengalees of Dearah, Hooghly District, West Bengal, India: relationship with educational status and food habit. | A cross-sectional study of 1203 adult (> 18 years of age) Bengalees of Dearah, Hooghly District, West Bengal, India, was undertaken to evaluate the prevalence of undernutrition and the relationship of educational level and food habit with undernutrition. Height and weight were measured and body mass index (BMI) compute... | 10.1127/0003-5548/2009/0016 | 19,739,463 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004522:Educational Status; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D015994:Incidence; D007194:India; D008297:Male; D044342:Malnutrition; D008875:Middle Aged; D009752:Nutritional Status; D018570:Risk Assessment; D012307:Risk F... | Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur | 2,009 | |
Frequency scale for symptoms of gastroesophageal reflux disease predicts the need for addition of prokinetics to proton pump inhibitor therapy. | BACKGROUND AND AIM
Proton pump inhibitor (PPI) monotherapy cannot cure all cases of gastroesophageal reflux disease (GERD), and combination therapy with prokinetics and PPI achieves symptomatic improvement for some GERD patients. Few studies have been performed to predict the need for prokinetics.
METHODS
Subjects we... | 10.1111/j.1440-1746.2007.05218.x | 18,028,348 | D004359:Drug Therapy, Combination; D005260:Female; D005764:Gastroesophageal Reflux; D005765:Gastrointestinal Agents; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D054328:Proton Pump Inhibitors; D012189:Retrospective Studies; D011795:Surveys and Questionnaires | Journal of gastroenterology and hepatology | 2,008 | D005765:Gastrointestinal Agents; D054328:Proton Pump Inhibitors |
Inelastic transport and low-bias rectification in a single-molecule diode. | Designing, controlling, and understanding rectification behavior in molecular-scale devices has been a goal of the molecular electronics community for many years. Here we study the transport behavior of a single molecule diode, and its nonrectifying, symmetric counterpart at low temperatures, and at both low and high b... | 10.1021/nn2030644 | 21,932,824 | D004548:Elasticity; D004553:Electric Conductivity; D055615:Electrical Equipment and Supplies; D004566:Electrodes; D004583:Electrons; D004867:Equipment Design; D060739:Phonons; D011743:Pyrimidines; D013438:Sulfhydryl Compounds; D013696:Temperature | ACS nano | 2,011 | D011743:Pyrimidines; D013438:Sulfhydryl Compounds; C030986:pyrimidine |
Big-endothelin in acute ischemic stroke. | Plasma big-endothelin (BE) in 12 patients with acute severe ischemic stroke was studied. Six patients developed complete supratentorial infarctions, and six patients had severe infarctions of pons, cerebellum, and/or medulla. Significant elevations of BE during the first 2 weeks after the initial stroke and significant... | 10.1016/S1052-3057(10)80070-9 | 26,487,462 | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association | 1,993 | ||
Decrease of CD4-positive T lymphocytes in workers exposed to benzidine and beta-naphthylamine. | T lymphocyte subpopulations (CD4+, CD8+, and CD3+ cells), Leu 11a-(CD16) positive lymphocytes, and total lymphocytes in peripheral blood in 52 male dyestuff workers were analyzed to determine the effects of benzidine and beta-naphthylamine on the human immune system. The workers had been exposed prior to 1972 to benzid... | 10.1080/00039896.1993.9940360 | 8,102,843 | D015081:2-Naphthylamine; D000328:Adult; D000368:Aged; D001560:Benzidines; D017252:CD3 Complex; D015496:CD4-Positive T-Lymphocytes; D016827:CD8 Antigens; D004396:Coloring Agents; D004784:Environmental Monitoring; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009369:Neoplasms; D016273:Occup... | Archives of environmental health | 1,993 | D001560:Benzidines; D017252:CD3 Complex; D016827:CD8 Antigens; D004396:Coloring Agents; D017452:Receptors, IgG; C029876:benzidine; D015081:2-Naphthylamine |
Inhibition of bcl-2 with antisense oligonucleotides induces apoptosis and increases the sensitivity of AML blasts to Ara-C. | We have previously shown that blasts from acute myeloid leukaemia (AML) patients which grow autonomously in culture have high bcl-2 expression which in turn has been linked to a poor clinical response to chemotherapy. The bcl-2 protein promotes cell survival by preventing the onset of apoptosis or programmed cell death... | 7,845,007 | D017209:Apoptosis; D001483:Base Sequence; D003561:Cytarabine; D016178:Granulocyte-Macrophage Colony-Stimulating Factor; D006801:Humans; D015470:Leukemia, Myeloid, Acute; D008969:Molecular Sequence Data; D016376:Oligonucleotides, Antisense; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D01440... | Leukemia | 1,995 | D016376:Oligonucleotides, Antisense; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D003561:Cytarabine; D016178:Granulocyte-Macrophage Colony-Stimulating Factor | |
The epigenetic landscape of T-cell acute lymphoblastic leukemia. | The genetic landscape of T-ALL has been very actively explored during the past decades. This leads to an overwhelming body of exciting novel findings providing insight into (1) the genetic heterogeneity of the disease with marked genetic subsets, (2) the mechanisms by which aberrant T-cell development drive leukemogene... | 24,786,297 | D002454:Cell Differentiation; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D016147:Genes, Tumor Suppressor; D015894:Genome, Human; D006657:Histones; D006801:Humans; D009857:Oncogenes; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | The international journal of biochemistry & cell biology | 2,014 | D006657:Histones | |
Nursing Information System. | Nursing Information System (NIS) is a part of a health care information system that deals with nursing aspects, particularly the maintenance of the nursing record. The several objectives that a Nursing Information system should meet in order to succeed its aims, cover the users' needs and operate properly are described... | 15,460,230 | D006284:Health Plan Implementation; D006801:Humans; D007256:Information Systems; D009729:Nursing | Studies in health technology and informatics | 2,002 | ||
Providing care for children with type 1 diabetes in kindergartens and schools. | INTRODUCTION
Type 1 diabetes in the paediatric population is becoming a serious social problem affecting an increasing number of families with small, dependent children. Polish educational institutions are not prepared to provide care for students with diabetes. There are no nurses who, by law, are responsible for taki... | 10.5114/pedm.2020.98998 | 33,554,495 | D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1; D006801:Humans; D010290:Parents; D012574:Schools; D013334:Students; D011795:Surveys and Questionnaires | Pediatric endocrinology, diabetes, and metabolism | 2,020 | |
Evidence-based decision-making in nursing - development and piloting of a train-the-trainer concept for teachers at schools for health care professionals: A pilot study. | BACKGROUND
Train-the-trainer concepts (TTT concepts) to impart evidence-based practice competences aim at promoting the implementation of evidence-based practice. The aim of this study was to develop and pilot-test a TTT training program for teachers at schools for health care professionals. The program is based on the... | 10.1016/j.zefq.2022.08.008 | 36,328,933 | D006801:Humans; D010865:Pilot Projects; D005858:Germany; D003479:Curriculum; D006282:Health Personnel; D012574:Schools | Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen | 2,022 | |
Optimizing outcomes in laparoscopic urologic training: toward a standardized global consensus. | BACKGROUND AND PURPOSE
Laparoscopic urologic surgery (LUS) is one of the fastest growing subspecialties in the surgical world. The procedures require technical expertise and finesse; unlike their open counterparts, there is significant limitation in the margin for error. Various ethical, medicolegal, and health economy... | 10.1089/end.2007.9968 | 17,451,326 | D032921:Consensus; D005257:Fellowships and Scholarships; D006801:Humans; D010535:Laparoscopy; D015203:Reproducibility of Results; D016896:Treatment Outcome; D013520:Urologic Surgical Procedures | Journal of endourology | 2,007 | |
Thermal fluctuations in shape, thickness, and molecular orientation in lipid bilayers. II. Finite surface tensions. | We investigate the role of lipid chemical potential on the shape, thickness, and molecular orientation (lipid tilting relative to the monolayer surface normal) of lipid bilayers via a continuum-level model. We predict that decreasing the chemical potential at constant temperature, which is associated with an increase i... | 10.1063/1.4818530 | 24,007,028 | D008051:Lipid Bilayers; D056004:Molecular Dynamics Simulation; D013500:Surface Tension; D013696:Temperature | The Journal of chemical physics | 2,013 | D008051:Lipid Bilayers |
Inside job: Staphylococcus aureus host-pathogen interactions. | Staphylococcus aureus is a notorious opportunistic pathogen causing a plethora of diseases. Recent research established that once phagocytosed by neutrophils and macrophages, a certain percentage of S. aureus is able to survive within these phagocytes which thereby even may contribute to dissemination of the pathogen. ... | 10.1016/j.ijmm.2017.11.009 | 29,217,333 | D000818:Animals; D001343:Autophagy; D003593:Cytoplasm; D054884:Host-Pathogen Interactions; D006801:Humans; D057131:Immune Evasion; D008264:Macrophages; D051379:Mice; D010586:Phagocytes; D010587:Phagocytosis; D010588:Phagosomes; D013203:Staphylococcal Infections; D013211:Staphylococcus aureus | International journal of medical microbiology : IJMM | 2,018 | |
MICRODOSIMETRIC UNDERSTANDING OF DOSE RESPONSE AND RELATIVE EFFICIENCY OF THERMOLUMINESCENCE DETECTORS. | LiF:Mg,Ti detectors show relative efficiency η for heavy charged particles significantly lower than one. It was for a long time not recognised that η varies also for electron energies and, as a consequence for photons. For LiF:Mg,Cu,P detectors measured photon energy response was named 'anomalous' because it differed s... | 10.1093/rpd/ncaa211 | 33,418,564 | D005459:Fluorides; D007477:Ions; D018020:Lithium Compounds; D017785:Photons; D011874:Radiometry; D013819:Thermoluminescent Dosimetry; D014025:Titanium | Radiation protection dosimetry | 2,020 | D007477:Ions; D018020:Lithium Compounds; D014025:Titanium; D005459:Fluorides |
Setup error assessment based on "Sphere-Mask" Optical Positioning System: Results from a multicenter study. | Background
The setup accuracy plays an extremely important role in the local control of tumors. The purpose of this study is to verify the feasibility of "Sphere-Mask" Optical Positioning System (S-M_OPS) for fast and accurate setup.
Methods
From 2016 to 2021, we used S-M_OPS to supervise 15441 fractions in 1981patie... | 10.3389/fonc.2022.918296 | 36,267,985 | Frontiers in oncology | 2,022 | ||
Abnormal global-brain functional connectivity and its relationship with cognitive deficits in drug-naive first-episode adolescent-onset schizophrenia. | Abnormal functional connectivity (FC) has been reported in drug-naive first-episode adolescent-onset schizophrenia (AOS) with inconsistent results due to differently selected regions of interest. The voxel-wise global-brain functional connectivity (GFC) analysis can help explore abnormal FC in an unbiased way in AOS. A... | 10.1007/s11682-021-00597-3 | 34,997,425 | D000293:Adolescent; D001921:Brain; D001931:Brain Mapping; D003071:Cognition; D006801:Humans; D008279:Magnetic Resonance Imaging; D012559:Schizophrenia | Brain imaging and behavior | 2,022 | |
Metallothionein and anticancer agents: the role of metallothionein in cancer chemotherapy. | Metallothioneins (MTs) are intracellular proteins containing the highest amount of thiol groups within the cytoplasm. These thiol groups are able to bind several cytotoxic agents, such as platinum compounds and alkylating agents. Increased levels of MT are one mechanism of resistance to these anticancer drugs, as intra... | 10.1007/BF01050214 | 8,145,055 | D000477:Alkylating Agents; D000818:Animals; D000970:Antineoplastic Agents; D001932:Brain Neoplasms; D002455:Cell Division; D004351:Drug Resistance; D006801:Humans; D008668:Metallothionein; D017671:Platinum Compounds | Journal of neuro-oncology | 1,993 | D000477:Alkylating Agents; D000970:Antineoplastic Agents; D017671:Platinum Compounds; D008668:Metallothionein |
Roflumilast reverses CFTR-mediated ion transport dysfunction in cigarette smoke-exposed mice. | BACKGROUND
Dysfunction in cystic fibrosis transmembrane conductance regulator (CFTR) can be elicited by cigarette smoke and is observed in patients with chronic bronchitis. We have previously demonstrated in human airway epithelial cell monolayers that roflumilast, a clinically approved phosphodiesterase 4 inhibitor th... | 10.1186/s12931-017-0656-0 | 28,923,049 | D000631:Aminopyridines; D000818:Animals; D001549:Benzamides; D000073865:Cigarette Smoking; D003521:Cyclopropanes; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D005260:Female; D019570:Inhalation Exposure; D017136:Ion Transport; D008297:Male; D051379:Mice; D018181:Mice, Inbred CFTR; D058988:Phosphodiester... | Respiratory research | 2,017 | D000631:Aminopyridines; D001549:Benzamides; D003521:Cyclopropanes; D058988:Phosphodiesterase 4 Inhibitors; C424423:Roflumilast; D019005:Cystic Fibrosis Transmembrane Conductance Regulator |
[Experimental study of the thrombolytic effects in a canine model of pulmonary thromboembolism induced by autologous radioactive blood clots]. | OBJECTIVE
To compare the thrombolytic effects of the two dosing regimes with urokinase (UK) in a canine model of pulmonary thromboembolism induced by radioactive blood clots.
METHODS
Seventeen dogs were randomly assigned into three groups: the control group, the UK(2h) group (UK infused over 2 hours) and the UK(12h) ... | 14,990,182 | D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D008297:Male; D011655:Pulmonary Embolism; D013671:Technetium Tc 99m Sulfur Colloid; D015912:Thrombolytic Therapy; D014568:Urokinase-Type Plasminogen Activator | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases | 2,004 | D013671:Technetium Tc 99m Sulfur Colloid; D014568:Urokinase-Type Plasminogen Activator | |
Prevalence of enteric protozoa in human immunodeficiency virus (HIV)-positive and HIV-negative men who have sex with men from Sydney, Australia. | A prospective, comparative study of the prevalence of enteric protozoa was determined among human immunodeficiency virus (HIV)- positive and HIV-negative men who have sex with men (MSM) in Sydney, Australia. A total of 1,868 patients submitted stool specimens; 1,246 were from MSM (628 HIV positive and 618 HIV positive)... | 17,360,882 | D000818:Animals; D016845:Blastocystis hominis; D003458:Cryptosporidium; D004748:Entamoeba histolytica; D056890:Eukaryota; D005243:Feces; D006679:HIV Seropositivity; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D015995:Prevalence; D011446:Prospective Studies | The American journal of tropical medicine and hygiene | 2,007 | ||
New application of microwave digestion-inductively coupled plasma-mass spectrometry for multi-element analysis in komatiites. | A new method using microwave digestion combined with inductively coupled plasma-mass spectrometry (ICP-MS) was studied to analyze the elemental composition of a variety of komatiites samples. Microwave digestion consisted in two-stage heating and pressurizing acid treatments for maximum dissolution of the samples. We r... | 10.1016/j.aca.2008.09.008 | 18,929,001 | Analytica chimica acta | 2,008 | ||
Characterization of the Heat Shock Transcription Factor Family in Medicago sativa L. and Its Potential Roles in Response to Abiotic Stresses. | Heat shock transcription factors (HSFs) are important regulatory factors in plant stress responses to various biotic and abiotic stresses and play important roles in growth and development. The HSF gene family has been systematically identified and analyzed in many plants but it is not in the tetraploid alfalfa genome.... | 10.3390/ijms241612683 | 37,628,861 | D000076249:Heat Shock Transcription Factors; D000455:Medicago sativa; D057891:Tetraploidy; D058639:Cold-Shock Response; D000077323:Salt Stress; D015850:Interleukin-6 | International journal of molecular sciences | 2,023 | D000076249:Heat Shock Transcription Factors; D015850:Interleukin-6 |
Intraocular wooden foreign body clinically resembling a pearl cyst. | Five years after injuring his right eye with a wooden arrow, an 11-year-old boy had an iris lesion resembling a pearl cyst. Surgery demonstrated an intraocular wooden foreign body. Wooden foreign bodies are uncommon but may be surprisingly well tolerated if uncontaminated. A differential diagnosis of iris mass lesions ... | 10.1001/archopht.1977.04450050113013 | 860,945 | D000867:Anterior Chamber; D002648:Child; D003560:Cysts; D003937:Diagnosis, Differential; D005129:Eye Foreign Bodies; D006801:Humans; D008297:Male; D014934:Wood | Archives of ophthalmology (Chicago, Ill. : 1960) | 1,977 | |
Chronic disease in elderly couples: are women more responsive to their spouses' health condition than men? | OBJECTIVE
The aim of the present study is to increase knowledge regarding associations between couples' health condition and psychological distress in both spouses considering gender as well as patient/spouse status.
METHOD
We examined a community-based sample of 995 elderly couples in which either both spouses were ... | 10.1016/s0022-3999(01)00279-3 | 11,728,511 | D000368:Aged; D001007:Anxiety; D002908:Chronic Disease; D003863:Depression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008393:Marriage; D011446:Prospective Studies; D012720:Severity of Illness Index; D012737:Sex Factors | Journal of psychosomatic research | 2,001 | |
Toward More Inclusive Work Organizations by Redesigning Work. | Inclusive Work Redesign (IWR) is an innovative strategy to create feasible job opportunities for job seekers from vulnerable groups at the labor market, in particular people with disabilities, in such a way that it contributes to sustainable employment for all staff and to the organization's performance. As an element ... | 10.3389/fresc.2022.861561 | 36,189,072 | Frontiers in rehabilitation sciences | 2,022 | ||
A magnetic switch for the control of cell death signalling in in vitro and in vivo systems. | The regulation of cellular activities in a controlled manner is one of the most challenging issues in fields ranging from cell biology to biomedicine. Nanoparticles have the potential of becoming useful tools for controlling cell signalling pathways in a space and time selective fashion. Here, we have developed magneti... | 10.1038/nmat3430 | 23,042,417 | D000818:Animals; D017209:Apoptosis; D016923:Cell Death; D002478:Cells, Cultured; D058185:Magnetite Nanoparticles; D015398:Signal Transduction; D015027:Zebrafish | Nature materials | 2,012 | D058185:Magnetite Nanoparticles |
Complex interactions between insect-borne rice viruses and their vectors. | Insect-borne rice viral diseases are widespread and economically important in many rice-growing countries. Long-term associations between rice viruses and their insect vectors result in evolutionary trade-offs that maintain a balance between the fitness cost of the viral infection of insects and the persistent transmis... | 10.1016/j.coviro.2018.07.005 | 30,031,984 | D000818:Animals; D017209:Apoptosis; D001343:Autophagy; D054884:Host-Pathogen Interactions; D007113:Immunity, Innate; D007303:Insect Vectors; D012275:Oryza; D010935:Plant Diseases; D010942:Plant Viruses; D015398:Signal Transduction; D014779:Virus Replication | Current opinion in virology | 2,018 | |
Characterization of the promoter region of the human IGHMBP2 (Smubp-2) gene and its response to TPA in HL-60 cells. | Immunoglobulin mu-binding protein 2 (IGHMBP2/Smubp-2) is a helicase motif-containing DNA-binding protein that has been suggested to regulate various nuclear functions. Recent studies indicated that mutations in the IGHMBP2 gene are responsible for spinal muscular atrophy with respiratory distress type I (SMARD1). Howev... | 10.1016/j.gene.2010.04.014 | 20,441,787 | D000818:Animals; D002454:Cell Differentiation; D004268:DNA-Binding Proteins; D051268:GA-Binding Protein Transcription Factor; D018922:HL-60 Cells; D006801:Humans; D051379:Mice; D011401:Promoter Regions, Genetic; D011518:Proto-Oncogene Proteins; D050783:Proto-Oncogene Proteins c-ets; D013755:Tetradecanoylphorbol Acetate... | Gene | 2,010 | D004268:DNA-Binding Proteins; D051268:GA-Binding Protein Transcription Factor; C489892:IGHMBP2 protein, human; D011518:Proto-Oncogene Proteins; D050783:Proto-Oncogene Proteins c-ets; D015534:Trans-Activators; D014157:Transcription Factors; D050807:ets-Domain Protein Elk-1; C064368:proto-oncogene protein Spi-1; D013755:... |
The role of genomic imprinting in implantation. | OBJECTIVES
To outline the possible role of the imprinted genes in early human embryogenesis and implantation.
DATA IDENTIFICATION
Literature review.
STUDY SELECTION
Studies examining the issues of genomic imprinting, implantation, gestational trophoblastic diseases, placental gene expression, and trophoblast invasi... | 7,523,201 | D000818:Animals; D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D004303:Dosage Compensation, Genetic; D010064:Embryo Implantation; D005260:Female; D018392:Genomic Imprinting; D006801:Humans; D007335:Insulin-Like Growth Factor II; D008297:Male; D010446:Peptide Fragments | Fertility and sterility | 1,994 | D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments; D007335:Insulin-Like Growth Factor II | |
Computational Insights into Dynamics of Protein Aggregation and Enzyme-Substrate Interactions. | In this Perspective, the roles of protein dynamics have been discussed in the aggregation of amyloid beta (Aβ) peptides and formation of enzyme-substrate complexes of beta-secretase (BACE1) and insulin-degrading enzyme (IDE). The studies regarding the influence of individual amino acid residues and specific regions on ... | 10.1021/jz301597k | 26,290,973 | The journal of physical chemistry letters | 2,012 | ||
[MRSA respiratory tract infection]. | Sputum isolates of MRSA have been on the increase, recently. Preventive measures against MRSA nosocomial infections have become important in Japanese hospitals. Clinical study was performed on 29 patients from whom MRSA was isolated more than 10(7) cfu/ml using the quantitative sputum culture method. All had a history ... | 1,507,430 | D000900:Anti-Bacterial Agents; D003428:Cross Infection; D004352:Drug Resistance, Microbial; D006801:Humans; D016106:Methicillin Resistance; D012141:Respiratory Tract Infections; D013183:Sputum; D013203:Staphylococcal Infections; D013211:Staphylococcus aureus | Nihon rinsho. Japanese journal of clinical medicine | 1,992 | D000900:Anti-Bacterial Agents | |
Dermatophagoides pteronyssinus and bioelectric properties of airway epithelium: role of cysteine proteases. | Several epidemiological studies suggest that exposure to house dust mite allergens plays a role in the pathogenesis of asthma. Since many of these allergens exhibit enzymatic properties, they may damage the airway epithelium. To characterize the effects of low doses of Dermatophagoides pteronyssinus on the airway epith... | 10.1034/j.1399-3003.2000.16b20.x | 10,968,508 | D000818:Animals; D039741:Antigens, Dermatophagoides; D003546:Cysteine Endopeptidases; D004229:Dithiothreitol; D004553:Electric Conductivity; D004789:Enzyme Activation; D004847:Epithelial Cells; D006023:Glycoproteins; D066298:In Vitro Techniques; D008297:Male; D008962:Models, Theoretical; D051381:Rats; D011917:Rats, Inb... | The European respiratory journal | 2,000 | D039741:Antigens, Dermatophagoides; D006023:Glycoproteins; D003546:Cysteine Endopeptidases; D004229:Dithiothreitol |
Acute confusional migraine: variant of transient global amnesia. | Acute confusional migraine in children and transient global amnesia in adults share a number of similar clinical manifestations. Acute confusional migraine in 6 children (mean age: 11.7 years; range: 7.5-17 years) was characterized by transient episodes of amnesia and acute confusion lasting 1-12 hours. Episodes were p... | 10.1016/0887-8994(94)00154-t | 7,779,209 | D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000647:Amnesia; D002648:Child; D003221:Confusion; D004569:Electroencephalography; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient; D008297:Male; D008881:Migraine Disorders; D009778:Occipital Lobe | Pediatric neurology | 1,995 | |
Effect of radiofrequency catheter ablation on left atrial structure and function in patients with different types of atrial fibrillation. | Radiofrequency catheter ablation (RFCA) is widely used to treat atrial fibrillation (AF), but its effect on left atrial (LA) remodeling in patients with AF is not completely clarified. Few studies have reported the changes in structure and function of the left atrium in patients with different types of AF after RFCA. T... | 10.1038/s41598-022-13725-w | 35,681,013 | D001281:Atrial Fibrillation; D064752:Atrial Remodeling; D017115:Catheter Ablation; D004452:Echocardiography; D006325:Heart Atria; D006801:Humans; D016896:Treatment Outcome | Scientific reports | 2,022 | |
The National Leprosy Control Programme of Zimbabwe a data analysis, 1983-1992. | Prevalence and detection rates of leprosy in Zimbabwe as well as patient characteristics were reported by the National Leprosy Control Programme over the 10-year period 1983-1992. The control programme made a new start in 1983 when multidrug therapy was introduced. Prevalence per 10,000 population declined steeply from... | 10.5935/0305-7518.19980006 | 9,628,095 | D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D003906:Developing Countries; D005260:Female; D006801:Humans; D015994:Incidence; D017053:Infection Control; D007918:Leprosy; D008297:Male; D008875:Middle Aged; D009313:National Health Programs; D015995:Prevalence; D012042:Registri... | Leprosy review | 1,998 | |
D-Dimer and Fibrinogen Values according to the Localization of Deep Venous Thrombosis. | D-dimer and fibrinogen are nonspecific diagnostic biomarkers for venous thromboembolism (VTE). The aim of this article was to present the values of D-dimer and fibrinogen in relation to the anatomical localization of deep vein thrombosis (DVT). This was an observational study, which included 1,142 patients hospitalized... | 10.1055/s-0042-1759819 | 37,927,846 | The International journal of angiology : official publication of the International College of Angiology, Inc | 2,023 | ||
Synergy between intraepithelial lymphocytes and lamina propria T cells drives intestinal inflammation during infection. | Oral infection of C57BL/6 mice with Toxoplasma gondii triggers severe necrosis in the ileum within 7-10 days of infection. Lesion development is mediated by Th-1 cytokines, CD4+ T cells, and subepithelial bacterial translocation. As such, these features share similarity to Crohn's disease. Recently, we uncovered a role... | 10.1038/mi.2011.31 | 21,796,113 | D019264:Adoptive Transfer; D000818:Animals; D019072:Antibiotic Prophylaxis; D015496:CD4-Positive T-Lymphocytes; D002450:Cell Communication; D003424:Crohn Disease; D004195:Disease Models, Animal; D006801:Humans; D007082:Ileum; D007249:Inflammation; D007413:Intestinal Mucosa; D051379:Mice; D008810:Mice, Inbred C57BL; D01... | Mucosal immunology | 2,011 | D016693:Receptors, Antigen, T-Cell, alpha-beta |
Single lung transplantation for canine pulmonary hypertension. | BACKGROUND
In spite of recent reports of the clinical application of single lung transplantation for pulmonary hypertension, there is little underlying experimental data because of the lack of a reliable animal pulmonary hypertensive transplant model. We have established a pulmonary hypertensive model in beagles with d... | 9,171,272 | D000818:Animals; D002315:Cardiopulmonary Bypass; D004195:Disease Models, Animal; D004285:Dogs; D006439:Hemodynamics; D006976:Hypertension, Pulmonary; D016040:Lung Transplantation; D016686:Monocrotaline; D009929:Organ Size; D011652:Pulmonary Circulation; D015203:Reproducibility of Results | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | 1,997 | C014114:monocrotaline pyrrole; D016686:Monocrotaline | |
Diagnosis and surgical removal of a granulosa-theca cell tumor in a mare. | An 8-year-old mare showed stallion-like behavior and aggressiveness. A granulosa-theca cell tumor was tentatively diagnosed based on history, transrectal palpation, and ultrasonography, and surgically removed. Serological levels of testosterone and inhibin were elevated. Histopathological examination confirmed the diag... | 16,152,723 | D000818:Animals; D001522:Behavior, Animal; D005260:Female; D006106:Granulosa Cell Tumor; D006734:Horse Diseases; D006736:Horses; D007265:Inhibins; D010051:Ovarian Neoplasms; D013739:Testosterone; D016896:Treatment Outcome | The Canadian veterinary journal = La revue veterinaire canadienne | 2,005 | D013739:Testosterone; D007265:Inhibins | |
Isolas of periodic passive Q-switching self-pulsations in the three-level:two-level model for a laser with a saturable absorber. | We show that a fundamental feature of the three-level:two-level model, used to describe molecular monomode lasers with a saturable absorber, is the existence of isolas of periodic passive Q-switching (PQS) self-pulsations. A common feature of these closed families of periodic solutions is that they contain regions of s... | 10.1103/PhysRevE.84.056207 | 22,181,484 | D000388:Air; D000465:Algorithms; D006859:Hydrogen; D007834:Lasers; D015233:Models, Statistical; D017711:Nonlinear Dynamics; D010825:Physics; D013997:Time Factors | Physical review. E, Statistical, nonlinear, and soft matter physics | 2,011 | D006859:Hydrogen |
[Effect of bovine plasma fibronectin on rat papilla cells in vitro]. | OBJECTIVE
To observe the effect of exogenous fibronectin (FN) on the rat dental papilla tissues and cells.
METHODS
Tooth germs of first mandibular molars obtained from 17-day-old rat (SD) embryos were cultured for 3, 6, 9 days on millipore filters in DMEM supplemented with 10% FCS, 50 mg/L Vitamin c. The dental papil... | 11,774,659 | D000818:Animals; D002417:Cattle; D002454:Cell Differentiation; D003771:Dental Papilla; D005260:Female; D005353:Fibronectins; D009924:Organ Culture Techniques; D051381:Rats; D017207:Rats, Sprague-Dawley | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology | 1,998 | D005353:Fibronectins | |
[Causes of local forms of primary tuberculosis in ways of their detection in children in an area with high morbidity rates in the adult population]. | Thirty-six children with new-onset local tuberculosis were followed up to assess its causes and the ways of its detection. The predominant form of primary tuberculosis was that of inthrathoracic lymph nodes. Six examinees had complicated tuberculosis, the latter being attended by circumscribed lymphogenic semination in... | 18,320,655 | D000328:Adult; D001500:BCG Vaccine; D002391:Catchment Area, Health; D002648:Child; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening; D015995:Prevalence; D012426:Russia; D014397:Tuberculosis, Pulmonary | Problemy tuberkuleza i boleznei legkikh | 2,008 | D001500:BCG Vaccine | |
Tooth-related issues. | Several conditions exist around teeth that may predispose the periodontium to disease. These situations may occur as a result of the condition or position of teeth or as a result of tooth treatment. In certain cases these tooth-related factors may contribute to the initiation of periodontal disease. While the etiology ... | 10.1902/annals.1999.4.1.91 | 10,863,380 | D003788:Dental Pulp Diseases; D003793:Dental Restoration, Permanent; D006801:Humans; D010518:Periodontitis; D014071:Tooth Abnormalities; D014076:Tooth Diseases | Annals of periodontology | 1,999 | |
[Influenza surveillance in nine consecutive seasons, 2003-2012: results from National Influenza Reference Laboratory, Istanbul Faculty Of Medicine, Turkey]. | Influenza is a public health problem that affects 5-20% of the world population annually causing high morbidity and mortality especially in risk groups. In addition to determining prevention and treatment strategies with vaccines and antivirals, surveillance data plays an important role in combat against influenza. Sur... | 23,188,572 | D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype; D053122:Influenza A Virus, H3N2 Subtype; D009981:Influenza B virus; D007251:Influenza, Human; D008875:Middle Aged; D009296:Nasal Cavity; D014421:Turkey; D055815:Young Adul... | Mikrobiyoloji bulteni | 2,012 | ||
Pilot Phase II study of mazindol in children with attention deficit/hyperactivity disorder. | OBJECTIVE
Mazindol has been proposed as a potential treatment of children with attention deficit/hyperactivity disorder (ADHD). The purpose of this pilot study was to assess its pharmacokinetics, short-term efficacy, and safety.
SUBJECTS AND METHODS
A total of 24 children (aged 9-12 years) with ADHD (according to the... | 10.2147/DDDT.S65495 | 25,525,331 | D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity; D002648:Child; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008454:Mazindol; D010865:Pilot Projects; D012449:Safety | Drug design, development and therapy | 2,014 | D008454:Mazindol |
Wetting of CVD carbon films by polar and nonpolar liquids and implications for carbon nanopipes. | The handling, dispersion, manipulation, and functionalization of carbon nanotubes and nanopipes often require the use of solvents. Therefore, a good understanding of the wetting properties of the carbon nanotubes is needed. Such knowledge is also essential for the design of nanotube-based nanofluidic devices, which hol... | 10.1021/la0518288 | 16,460,107 | Langmuir : the ACS journal of surfaces and colloids | 2,006 | ||
Molecular profiling in fresh tissue with high tumor cell content promotes enrichment for aggressive adenocarcinomas in cervix. | Many emerging tools for comprehensive molecular profiling of malignant lesions demand fresh frozen tissue with a high tumor purity. Often, a tumor epithelial content of at least 80% is recommended. This approach may lead to a systematic bias, and therefore we explore if this introduces a selection of cases with a certa... | 25,123,963 | D000230:Adenocarcinoma; D000328:Adult; D014408:Biomarkers, Tumor; D002294:Carcinoma, Squamous Cell; D002584:Cervix Uteri; D018572:Disease-Free Survival; D005260:Female; D005629:Frozen Sections; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D016612:Paraffin Embedding; D010641:Phenotype; D011379:Prognosi... | Pathology, research and practice | 2,014 | D014408:Biomarkers, Tumor | |
Shear Wave and Strain Elastographic Features of the Brachial Plexus in Healthy Adults: Reliability of the Findings-a Pilot Study. | OBJECTIVES
To determine the sonoelastographic findings for the normal brachial plexus via shear wave elastography (SWE) and strain elastography (SE) and the reliability of the measurements.
METHODS
Thirty-nine healthy adult volunteers were included in the study. The brachial plexus was evaluated with SWE and SE at th... | 10.1002/jum.14584 | 29,480,537 | D000328:Adult; D001917:Brachial Plexus; D055119:Elastic Modulus; D004548:Elasticity; D054459:Elasticity Imaging Techniques; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012016:Reference Values; D015203:Reproducibility of Results | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | 2,018 | |
On the nature of organic and inorganic centers that bifurcate electrons, coupling exergonic and endergonic oxidation-reduction reactions. | Bifurcating electrons to couple endergonic and exergonic electron-transfer reactions has been shown to have a key role in energy conserving redox enzymes. Bifurcating enzymes require a redox center that is capable of directing electron transport along two spatially separate pathways. Research into the nature of electro... | 10.1039/c8cc01530a | 29,624,194 | Chemical communications (Cambridge, England) | 2,018 | ||
Mechanistic and mathematical inactivation studies of food spoilage fungi. | Fungal spoilage forms an increasing economic problem in the food industry. Chemical antifungals are becoming less attractive as food preservatives and hygiene agents due to the development of resistance and due to stricter legal regulations concerning the permitted concentrations. Finally, consumers tend to demand more... | 10.1006/fgbi.1999.1149 | 10,441,445 | D000935:Antifungal Agents; D005516:Food Microbiology; D005658:Fungi; D008954:Models, Biological | Fungal genetics and biology : FG & B | 1,999 | D000935:Antifungal Agents |
Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs. | Temporal control of physiology requires the interplay between gene networks involved in daily timekeeping and tissue function across different organs. How the circadian clock interweaves with tissue-specific transcriptional programs is poorly understood. Here, we dissected temporal and tissue-specific regulation at mul... | 10.1101/gr.222430.117 | 29,254,942 | D000818:Animals; D002843:Chromatin; D057906:Circadian Clocks; D002940:Circadian Rhythm; D004742:Enhancer Elements, Genetic; D005786:Gene Expression Regulation; D007668:Kidney; D008099:Liver; D051379:Mice; D009928:Organ Specificity; D011401:Promoter Regions, Genetic; D014157:Transcription Factors | Genome research | 2,018 | D002843:Chromatin; D014157:Transcription Factors |
Management of Postoperative Hypoxemia. | Hypoxemia is common in postoperative patients and is associated with prolonged hospital stays, high costs, and increased mortality. This review discusses the postoperative management of hypoxemia in regard to the use of conventional oxygen therapy, high-flow nasal cannula oxygen therapy, CPAP, and noninvasive ventilati... | 10.4187/respcare.08929 | 34,006,596 | D000072601:Cannula; D045422:Continuous Positive Airway Pressure; D006801:Humans; D000860:Hypoxia; D063087:Noninvasive Ventilation; D010100:Oxygen; D010102:Oxygen Inhalation Therapy | Respiratory care | 2,021 | D010100:Oxygen |
Effects of the Cc2d1a/Freud-1 Knockdown in the Hippocampus of BTBR Mice on the Autistic-Like Behavior, Expression of Serotonin 5-HT1A and D2 Dopamine Receptors, and CREB and NF-kB Intracellular Signaling. | The mechanisms of autism are of extreme interest due to the high prevalence of this disorder in the human population. In this regard, special attention is given to the transcription factor Freud-1 (encoded by the Cc2d1a gene), which regulates numerous intracellular signaling pathways and acts as a silencer for 5-HT1A s... | 10.1134/S0006297922100145 | 36,273,889 | D000818:Animals; D006801:Humans; D051379:Mice; D001321:Autistic Disorder; D004195:Disease Models, Animal; D004268:DNA-Binding Proteins; D006624:Hippocampus; D008810:Mice, Inbred C57BL; D016328:NF-kappa B; D011954:Receptors, Dopamine; D012097:Repressor Proteins; D034741:RNA, Small Interfering; D012701:Serotonin; D014157... | Biochemistry. Biokhimiia | 2,022 | C512283:CC2D1A protein, human; D004268:DNA-Binding Proteins; C522738:Freud-1 protein, mouse; D016328:NF-kappa B; D011954:Receptors, Dopamine; D012097:Repressor Proteins; D034741:RNA, Small Interfering; D012701:Serotonin; D014157:Transcription Factors; D017362:Cyclic AMP Response Element-Binding Protein |
Environmental boundaries as a mechanism for correcting and anchoring spatial maps. | Ubiquitous throughout the animal kingdom, path integration-based navigation allows an animal to take a circuitous route out from a home base and using only self-motion cues, calculate a direct vector back. Despite variation in an animal's running speed and direction, medial entorhinal grid cells fire in repeating place... | 10.1113/JP270624 | 26,563,618 | D000200:Action Potentials; D000818:Animals; D004777:Environment; D000071038:Grid Cells; D008959:Models, Neurological; D009949:Orientation; D013028:Space Perception | The Journal of physiology | 2,016 | |
Chromium uptake, retention and reduction in photosynthetic Euglena gracilis. | Photosynthetic Euglena gracilis grown with different K(2)CrO(4) concentrations was analyzed for its ability to take up, retain and reduce Cr(VI). For comparison, cells were also exposed to CrCl(3). Cellular Cr(VI) uptake at pH 7.2 showed a hyperbolic saturation pattern with K (m) of 1.1 mM, V (m) of 16 nmol (h x 10(7) ... | 10.1007/s00203-009-0469-8 | 19,290,509 | D000818:Animals; D002857:Chromium; D003470:Culture Media; D005056:Euglena gracilis; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D010084:Oxidation-Reduction; D013431:Sulfates | Archives of microbiology | 2,009 | D003470:Culture Media; D013431:Sulfates; D002857:Chromium |
The association between maternal air pollution exposure and the incidence of congenital heart diseases in children: A systematic review and meta-analysis. | Congenital heart diseases (CHDs) are a prevalent form of congenital malformations in newborns. Although previous studies have explored the association between maternal exposure to ambient air pollution and congenital anomalies in offspring, the results still remain ambiguous. To fill the knowledge gap, we performed a s... | 10.1016/j.scitotenv.2023.164431 | 37,268,121 | D005260:Female; D006801:Humans; D002648:Child; D007231:Infant, Newborn; D018811:Maternal Exposure; D000393:Air Pollutants; D015994:Incidence; D013771:Tetralogy of Fallot; D014188:Transposition of Great Vessels; D000397:Air Pollution; D006330:Heart Defects, Congenital; D052638:Particulate Matter; D004781:Environmental E... | The Science of the total environment | 2,023 | D000393:Air Pollutants; D052638:Particulate Matter |
Modulation of calcium channels in arterial smooth muscle cells by dihydropyridine enantiomers. | The actions of the optical enantiomers of BAY K 8644 and Sandoz 202,791 were studied on barium inward currents recorded using the whole-cell configuration of the patch clamp technique from enzymatically isolated smooth muscle cells from the rabbit ear artery. The enantiomers were applied by bath perfusion or rapidly by... | 10.1085/jgp.101.3.393 | 7,682,596 | D001498:3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; D000818:Animals; D001158:Arteries; D001464:Barium; D002120:Calcium Channel Agonists; D002121:Calcium Channel Blockers; D015220:Calcium Channels; D004095:Dihydropyridines; D066298:In Vitro Techniques; D00856... | The Journal of general physiology | 1,993 | D002120:Calcium Channel Agonists; D002121:Calcium Channel Blockers; D015220:Calcium Channels; D004095:Dihydropyridines; D001464:Barium; D001498:3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; C045796:SAN 202791 |
A novel DNA sequence database for analyzing human demographic history. | While there are now extensive databases of human genomic sequences from both private and public efforts to catalog human nucleotide variation, there are very few large-scale surveys designed for the purpose of analyzing human population history. Demographic inference from patterns of SNP variation in current large publ... | 10.1101/gr.075630.107 | 18,493,019 | D004247:DNA; D030561:Databases, Nucleic Acid; D003710:Demography; D014644:Genetic Variation; D006239:Haplotypes; D006801:Humans; D009711:Nucleotides; D020641:Polymorphism, Single Nucleotide; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA | Genome research | 2,008 | D009711:Nucleotides; D004247:DNA |
Angiotensin II enhances EGF receptor expression levels via ROS formation in HaCaT cells. | BACKGROUND
Recent work has shown a novel function of angiotensin II (Ang II) in skin wound healing in which reactive oxygen species might be involved. As Ang II is known to increase superoxide production by activating NADPH oxidase in some non-phagocytic cells, we hypothesized that the produced superoxide by NADPH acti... | 10.1016/j.jdermsci.2008.03.004 | 18,424,077 | D000804:Angiotensin II; D001483:Base Sequence; D002460:Cell Line; D049109:Cell Proliferation; D017931:DNA Primers; D066246:ErbB Receptors; D015870:Gene Expression; D006801:Humans; D015603:Keratinocytes; D019331:NG-Nitroarginine Methyl Ester; D009569:Nitric Oxide; D012333:RNA, Messenger; D017382:Reactive Oxygen Species;... | Journal of dermatological science | 2,008 | D017931:DNA Primers; D012333:RNA, Messenger; D017382:Reactive Oxygen Species; D000804:Angiotensin II; D019820:Xanthine; D009569:Nitric Oxide; D014969:Xanthine Oxidase; D066246:ErbB Receptors; D019331:NG-Nitroarginine Methyl Ester |
Variability of Greenhouse Gas Footprints of Field Tomatoes Grown for Processing: Interyear and Intercountry Assessment. | Our study provides an integrated analysis of the variability of greenhouse gas (GHG) footprints of field-grown tomatoes for processing. The global farm-specific data set of 890 observations across 14 countries over a three-year period (2013-2015) was obtained from farms grown under Unilever's sustainable agricultural c... | 10.1021/acs.est.7b04361 | 29,195,039 | D002677:Chile; D017752:Greenhouse Effect; D000074382:Greenhouse Gases; D007194:India; D018551:Solanum lycopersicum | Environmental science & technology | 2,018 | D000074382:Greenhouse Gases |
Per and poly-fluoroalkyl substances (PFAS) as a contaminant of emerging concern in surface water: A transboundary review of their occurrences and toxicity effects. | Per and poly-fluoroalkyl substances (PFAS) have been recognized as contaminants of emerging concerns by the United States Environmental Protection Agency (US EPA) due to their environmental impact. Several advisory guidelines were proposed worldwide aimed at limiting their occurrences in the aquatic environments, espec... | 10.1016/j.jhazmat.2021.126361 | 34,157,464 | D017738:Alkanesulfonic Acids; D000818:Animals; D060766:Drinking Water; D005466:Fluorocarbons; D006801:Humans; D013451:Sulfonic Acids; D014481:United States; D014484:United States Environmental Protection Agency; D014874:Water Pollutants, Chemical | Journal of hazardous materials | 2,021 | D017738:Alkanesulfonic Acids; D060766:Drinking Water; D005466:Fluorocarbons; D013451:Sulfonic Acids; D014874:Water Pollutants, Chemical |
Detection of human herpes virus type 6 DNA in precancerous lesions of the uterine cervix. | Human herpes virus type 6 (HHV-6) DNA has been suggested to be a cofactor to human papillomavirus (HPV) in cervical cancer. In a cross-sectional study, we investigated the association between HHV-6 DNA detected in cervical brushings and high-grade squamous intraepithelial lesions (HSIL), while controlling for genital i... | 10.1002/jmv.10229 | 12,376,970 | D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D003430:Cross-Sectional Studies; D004279:DNA, Viral; D005260:Female; D005838:Genotype; D015654:Herpesvirus 6, Human; D006801:Humans; D008875:Middle Aged; D016017:Odds Ratio; D011230:Precancerous Conditions; D012307:Risk Factors; D019349:Roseolovirus ... | Journal of medical virology | 2,002 | D004279:DNA, Viral |
Novel small-molecule compound VCP979 attenuates renal fibrosis in male rats with unilateral ureteral obstruction. | Renal fibrosis is a hallmark of chronic kidney disease, while efficient therapy against renal fibrosis is still lacking. In this study, we investigated the role of a novel small-molecule compound VCP979 on renal fibrosis and inflammation in a rat model of unilateral ureteral obstruction (UUO). One week after the UUO su... | 10.1177/15353702221147569 | 36,715,096 | D051381:Rats; D008297:Male; D000818:Animals; D014517:Ureteral Obstruction; D017207:Rats, Sprague-Dawley; D007674:Kidney Diseases; D053773:Transforming Growth Factor beta1; D007249:Inflammation; D005355:Fibrosis; D007668:Kidney | Experimental biology and medicine (Maywood, N.J.) | 2,023 | D053773:Transforming Growth Factor beta1 |
Regulation of Staphylococcus xylosus xylose utilization genes at the molecular level. | We have investigated the regulation of the operon encoding xylose utilization in Staphylococcus xylosus C2a and Staphylococcus carnosus TM300. For in vivo studies, transcriptional fusions of the xylAB regulatory region to the lipase gene from Staphylococcus hyicus were constructed. Repression of lipase activity depende... | 10.1128/jb.174.9.3042-3048.1992 | 1,569,030 | D001483:Base Sequence; D003001:Cloning, Molecular; D004269:DNA, Bacterial; D004790:Enzyme Induction; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D005947:Glucose; D008049:Lipase; D008969:Molecular Sequence Data; D010618:Phenanthrolines; D011993:Recombinant Fusion Proteins; D012045:Regulatory... | Journal of bacteriology | 1,992 | D004269:DNA, Bacterial; D010618:Phenanthrolines; D011993:Recombinant Fusion Proteins; D012097:Repressor Proteins; D014994:Xylose; D008049:Lipase; D005947:Glucose; C025205:1,10-phenanthroline |
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