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Assessing cervical dislocation as a humane euthanasia method in mice. | Research investigators often choose to euthanize mice by cervical dislocation (CD) when other methods would interfere with the aims of a research project. Others choose CD to assure death in mice treated with injected or inhaled euthanasia agents. CD was first approved for mouse euthanasia in 1972 by the AVMA Panel on ... | 22,776,194 | D018685:Anesthetics, Inhalation; D000827:Animal Welfare; D000818:Animals; D002574:Cervical Vertebrae; D037901:Euthanasia, Animal; D005260:Female; D007530:Isoflurane; D004204:Joint Dislocations; D008297:Male; D051379:Mice; D011859:Radiography; D013119:Spinal Cord Injuries; D013904:Thoracic Vertebrae | Journal of the American Association for Laboratory Animal Science : JAALAS | 2,012 | D018685:Anesthetics, Inhalation; D007530:Isoflurane | |
Regenerative repair after endoluminal injury in mice with specific antagonism of protease activated receptors on CD34+ vascular progenitors. | Tissue factor (TF) and thrombin are involved in intimal hyperplasia (IH) and remodelling following vascular injury. Because many neointimal smooth muscle cells (VSMCs) derive from circulating vascular progenitors (VPs), we investigated how thrombin influences VP phenotype and function. Following wire-induced carotid ar... | 10.1182/blood-2007-10-120295 | 18,268,094 | D000818:Animals; D018952:Antigens, CD34; D017209:Apoptosis; D002339:Carotid Arteries; D002454:Cell Differentiation; D049109:Cell Proliferation; D042783:Endothelial Cells; D006965:Hyperplasia; D051379:Mice; D009131:Muscle, Smooth, Vascular; D032389:Myocytes, Smooth Muscle; D010641:Phenotype; D044462:Receptors, Proteinas... | Blood | 2,008 | D018952:Antigens, CD34; D044462:Receptors, Proteinase-Activated; D018179:Receptors, Thrombin; D013925:Thromboplastin; D013917:Thrombin |
Severe sleep problems among infants in a normal population in Sweden: prevalence, severity and correlates. | The aim of this study was to explore the prevalence of parentally experienced infant sleep problems, with special interest in severe problems, in a total community sample of 2518 infants aged 6-18 mo. Correlates to severe sleep problems were sought. The families were approached using a questionnaire and 83% responded. ... | 10.1080/080352599750030086 | 10,626,522 | D001007:Anxiety; D002668:Child Rearing; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010290:Parents; D015995:Prevalence; D012893:Sleep Wake Disorders; D013548:Sweden | Acta paediatrica (Oslo, Norway : 1992) | 1,999 | |
Comparison of clinical outcomes of hydrophilic and lipophilic statins in patients with acute myocardial infarction. | BACKGROUND/AIMS
A controversy exists about which statin is preferable for patients with acute myocardial infarction (AMI), and clinical impacts of different statins according to lipophilicity have not been established.
METHODS
The 1,124 patients with AMI included in the present study were divided into hydrophilic- an... | 10.3904/kjim.2011.26.3.294 | 22,016,590 | D000368:Aged; D015415:Biomarkers; D002318:Cardiovascular Diseases; D016009:Chi-Square Distribution; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007723:Korea; D008055:Lipids; D008297:Male; D008875:M... | The Korean journal of internal medicine | 2,011 | D015415:Biomarkers; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008055:Lipids |
Effect of prolonged supplementation with daily supplements of selenomethionine and sodium selenite on glutathione peroxidase activity in blood of New Zealand residents. | Glutathione peroxidase (EC 1.11.1.9, GSH-Px) activities and selenium (Se) concentrations in blood of 12 New Zealand residents were followed during prolonged supplementation with physiological doses (100 microgram Se) of sodium selenite (selenite-Se) or selenomethionine (Semet-Se). GSH-Px activities increased in all sub... | 10.1093/ajcn/36.1.24 | 7,091,033 | D000328:Adult; D004912:Erythrocytes; D005260:Female; D005979:Glutathione Peroxidase; D006801:Humans; D008297:Male; D008875:Middle Aged; D009520:New Zealand; D010544:Peroxidases; D010949:Plasma; D020887:Selenious Acid; D012643:Selenium; D012645:Selenomethionine; D013997:Time Factors | The American journal of clinical nutrition | 1,982 | D012645:Selenomethionine; D010544:Peroxidases; D005979:Glutathione Peroxidase; D020887:Selenious Acid; D012643:Selenium |
[Orbital phlebography craniobasal meningiomas spreading into the orbit]. | Analysis of the results of orbital phlebography performed in 39 patients with cranio-orbital meningiomas testifies to the important diagnostic value of this methods of examination in determining the spread of craniobasal meningiomas to the orbit. By means of orbital phlebography it is possible not only to precisely def... | 7,245,977 | D006801:Humans; D008579:Meningioma; D009918:Orbital Neoplasms; D010690:Phlebography; D012888:Skull Neoplasms; D013100:Sphenoid Bone | Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko | 1,981 | ||
Localization of temporal preparation effects via trisected reaction time. | Previous research using nonchronometric measures in humans and animals has shown that warning signals can influence stages of processing throughout the reaction time (RT) interval. However, latency measures indicate that warning effects on RT are not due to the speeding of motor processes, at least not late ones. To be... | 10.1111/j.1469-8986.2007.00500.x | 17,343,715 | D000328:Adult; D003463:Cues; D004569:Electroencephalography; D004585:Electrooculography; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D010775:Photic Stimulation; D011930:Reaction Time | Psychophysiology | 2,007 | |
Property attribution in combined concepts. | Recent research shows that the judged likelihood of properties of modified nouns (baby ducks have webbed feet) is reduced relative to judgments for unmodified nouns (ducks have webbed feet). This modification effect has been taken as evidence both for and against the idea that combined concepts automatically inherit pr... | 10.1037/xlm0000085 | 25,419,816 | D003210:Concept Formation; D006801:Humans; D007600:Judgment; D011578:Psycholinguistics; D011581:Psychological Tests | Journal of experimental psychology. Learning, memory, and cognition | 2,015 | |
Toxic keratitis after use of wrongly labeled non-ophthalmic medication. | We present a 24-year-old female with trauma to her right eye. The patient was prescribed topical Tobramicin-dexamethasone eye drops but the pharmacy dispensed diclofenac diethyl amine ointment. The patient presented to the emergency room with lid edema, conjunctival injection and a corneal epithelial defect and toxic k... | 10.1016/j.jsps.2015.06.008 | 28,223,875 | Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society | 2,017 | ||
International conference on the healthy effect of virgin olive oil. | 1. Ageing represents a great concern in developed countries because the number of people involved and the pathologies related with it, like atherosclerosis, morbus Parkinson, Alzheimer's disease, vascular dementia, cognitive decline, diabetes and cancer. 2. Epidemiological studies suggest that a Mediterranean diet (whi... | 10.1111/j.1365-2362.2005.01516.x | 16,008,542 | D000375:Aging; D002318:Cardiovascular Diseases; D038441:Diet, Mediterranean; D004042:Dietary Fats, Unsaturated; D019317:Evidence-Based Medicine; D006801:Humans; D009369:Neoplasms; D000069463:Olive Oil; D018384:Oxidative Stress; D010938:Plant Oils | European journal of clinical investigation | 2,005 | D004042:Dietary Fats, Unsaturated; D000069463:Olive Oil; D010938:Plant Oils |
Stress Distribution Analysis of Novel Dental Mini-Implant Designs to Support Overdenture Prosthesis. | This study aimed to test and compare 2 novel dental mini-implant designs to support overdentures with a commercial model, regarding the stress distribution, by photoelastic analysis. Three different mini-implant designs (Ø 2.0 mm × 10 mm) were tested: G1-experimental threaded (design with threads and 3 longitudinal and... | 10.1563/aaid-joi-D-19-00354 | 33,690,819 | D015921:Dental Implants; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D003799:Dental Stress Analysis; D003828:Denture, Overlay; D013314:Stress, Mechanical | The Journal of oral implantology | 2,022 | D015921:Dental Implants |
Three new sulphur glycosides from the seeds of Descurainia sophia. | Three new sulphur glycosides, raphanuside B-D (1-3), together with a known sulphur glycoside, raphanuside (4) were isolated from the decoction of the seeds of Descurainia sophia (L.) Webb ex Prantl, and the compound 4 was reported for the first time from this plant. Their structures were identified by means of UV, IR, ... | 10.1080/14786419.2015.1135141 | 26,795,632 | D019607:Brassicaceae; D006027:Glycosides; D009682:Magnetic Resonance Spectroscopy; D011748:Pyrogallol; D012639:Seeds; D021241:Spectrometry, Mass, Electrospray Ionization; D013863:Thioglucosides | Natural product research | 2,016 | D006027:Glycosides; D013863:Thioglucosides; C548341:raphanuside; D011748:Pyrogallol |
Chromosomal end fusion resulting from telomere erosion increases susceptibility to radiation via multinucleation: effect of p53. | Loss of p53 tumor suppressor facilitates acquisition of telomerase activity. In fact, both p53 inactivation and telomerase activation are frequently found in human cancers. p53 inactivation, however, eliminates or attenuates the biological responses to telomerase inhibition and the eventual telomere erosion. We show th... | 16,964,373 | D000818:Animals; D016923:Cell Death; D002875:Chromosomes; D042822:Genomic Instability; D051379:Mice; D008938:Mitosis; D011836:Radiation Tolerance; D011995:Recombination, Genetic; D019098:Telomerase; D016615:Telomere; D016159:Tumor Suppressor Protein p53 | International journal of oncology | 2,006 | D016159:Tumor Suppressor Protein p53; D019098:Telomerase | |
Diazepam-induced changes on sleep and the EEG spectrum in mice: role of the alpha3-GABA(A) receptor subtype. | Benzodiazepines reduce EEG slow-wave activity in non-REM sleep by potentiating GABAergic neurotransmission at GABAA receptors via a modulatory binding site. However, the mechanisms of action underlying the effects of benzodiazepines on sleep and the sleep EEG are still unknown. Slow waves during sleep are generated by ... | 10.1046/j.1460-9568.2003.02651.x | 12,786,990 | D000818:Animals; D003975:Diazepam; D004569:Electroencephalography; D018757:GABA Modulators; D020646:Intralaminar Thalamic Nuclei; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains; D011963:Receptors, GABA-A; D012890:Sleep | The European journal of neuroscience | 2,003 | D018757:GABA Modulators; D011963:Receptors, GABA-A; D003975:Diazepam |
Benefits of Hearing Voices Groups & Other Self-Help Groups for Voice Hearers: A Systematic Review. | People who hear voices that others do not often rely on mainstream mental health services. Several alternatives to treatment have grown in popularity including "Hearing Voices Groups" and other self-help groups for voice hearers. The aim of this systematic review is to evaluate the current evidence relating to the use ... | 10.1080/01612840.2023.2189953 | 37,075,309 | D006801:Humans; D006212:Hallucinations; D012657:Self-Help Groups; D008605:Mental Health Services; D006309:Hearing; D000223:Adaptation, Psychological | Issues in mental health nursing | 2,023 | |
Studies of delayed systemic effects of ultraviolet B radiation (UVR) on the induction of contact hypersensitivity, 2. Evidence that interleukin-10 from UVR-treated epidermis is the critical mediator. | Acute, low-dose ultraviolet B radiation (UVR) alters cutaneous immunity at the local site as well as systemically. Within 2-3 days of UVR exposure, recipient mice lose their capacity to develop contact hypersensitivity (CH) when hapten is painted on unexposed skin. This loss correlates temporally with a functional defi... | 10.1046/j.1365-2567.2000.00934.x | 10,651,951 | D000818:Animals; D000911:Antibodies, Monoclonal; D003877:Dermatitis, Contact; D004139:Dinitrofluorobenzene; D004307:Dose-Response Relationship, Radiation; D004817:Epidermis; D007109:Immunity; D016753:Interleukin-10; D007509:Irritants; D015603:Keratinocytes; D008407:Mast Cells; D051379:Mice; D008809:Mice, Inbred C3H; D0... | Immunology | 2,000 | D000911:Antibodies, Monoclonal; D007509:Irritants; D016753:Interleukin-10; D004139:Dinitrofluorobenzene |
Psychophysiological stress response and memory in borderline personality disorder. | Background: Previously, we found that patients with borderline personality disorder (BPD) but not healthy controls (HC) showed improved memory retrieval after hydrocortisone administration. Objective: In this study, we examined whether increases in endogenous cortisol after psychosocial stress are associated with memor... | 10.1080/20008198.2019.1568134 | 30,788,063 | European journal of psychotraumatology | 2,019 | ||
Is very high C-reactive protein in young adults associated with indicators of chronic disease risk? | BACKGROUND
Cases with very high C-reactive protein (CRP>10mg/L) are often dropped from analytic samples in research on risk for chronic physical and mental illness, but this convention could inadvertently result in excluding those most at risk. We tested whether young adults with very high CRP scored high on indicators... | 24,485,478 | D000293:Adolescent; D000328:Adult; D001774:Blood Chemical Analysis; D002097:C-Reactive Protein; D002648:Child; D002908:Chronic Disease; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D063588:National Longitudinal Study of Adolescent Health; D012189:Retrospective Studies; D012307:Risk Fa... | Psychoneuroendocrinology | 2,014 | D002097:C-Reactive Protein | |
Two cases of dissecting aneurysm of the distal posterior inferior cerebellar artery: possible involvement of segmental mediolytic arteriopathy in the pathogenesis. | BACKGROUND
Dissecting aneurysm of the posterior inferior cerebellar artery (PICA) uninvolved with the vertebral artery is rare. The exact pathohistological diagnosis might result in 'unknown' because the underlying pathoanatomical features are, for a variety of reasons, not always identified.
CASE DESCRIPTION
We repo... | 10.1016/j.clineuro.2004.01.007 | 15,708,226 | D000784:Aortic Dissection; D001167:Arteritis; D002531:Cerebellum; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D017540:Tunica Media | Clinical neurology and neurosurgery | 2,005 | |
Combination therapy with lamivudine and HB vaccine on chronic hepatitis B. | BACKGROUND AND AIM
Lamivudine (LAM) has problems of breakthrough hepatitis (BTH) and post-treatment relapse despite its significant effect for suppressing hepatitis B virus (HBV) replication. In order to find solutions for the problems, the efficacy of combination therapy of LAM plus hepatitis B (HB) vaccine in patient... | 10.1111/j.1872-034X.2007.00107.x | 17,627,638 | Hepatology research : the official journal of the Japan Society of Hepatology | 2,007 | ||
Cavitron assisted liver resection in a child. | Resection of a liver tumor using the cavitron ultrasound dissector is described. The technique is safe and minimizes blood loss. | 10.1016/s0022-3468(87)80242-7 | 3,033,191 | D002759:Adenoma, Bile Duct; D006528:Carcinoma, Hepatocellular; D002648:Child; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms; D014464:Ultrasonic Therapy | Journal of pediatric surgery | 1,987 | |
Nucleotide sequence homology of thirteen tobamovirus RNAs as determined by hybridization analysis with complementary DNA. | The extent of RNA sequence homology between 13 isolates of tobamoviruses has been estimated by hybridization analysis using radioactive complementary DNA. Hybrid formation between complementary [3H]DNA prepared against 7 of the tobamovirus RNAs and the RNAs of the 13 isolates was assayed with the single-strand-specific... | 10.1016/0042-6822(80)90303-7 | 18,631,835 | Virology | 1,980 | ||
Perceived competency at graduation among dental alumni of the University of the West Indies. | The aims of this study were to describe levels of self-rated competency of dental graduates from the University of the West Indies (UWI) and to investigate relationships with gender and the effect of curriculum change. A thirty-two item self-reported postal questionnaire was sent to UWI dental alumni (1994-2002). The q... | 14,761,178 | D001291:Attitude of Health Personnel; D002983:Clinical Competence; D018865:Dental Research; D003814:Dentistry, Operative; D003815:Dentists; D004497:Education, Dental; D005260:Female; D006801:Humans; D008297:Male; D018794:Problem-Based Learning; D012647:Self-Assessment; D012655:Self-Evaluation Programs; D012727:Sex Char... | Journal of dental education | 2,004 | ||
Endoscopic Doppler ultrasound for measurement of azygos blood flow. Validation against thermodilution and assessment of pharmacological effects of terlipressin in portal hypertension. | BACKGROUND
Endoscopic ultrasound (EUS) is a new modality allowing real-time flow measurements by means of the Doppler technique. The aim of the study was to evaluate azygos blood flow measurements by endoscopic ultrasound.
METHODS
Measurements of azygos blood flow by EUS and by the thermodilution technique were compa... | 10.1080/003655201750074717 | 11,305,522 | D000328:Adult; D000368:Aged; D001401:Azygos Vein; D001783:Blood Flow Velocity; D018592:Cross-Over Studies; D004311:Double-Blind Method; D019160:Endosonography; D005260:Female; D006801:Humans; D006975:Hypertension, Portal; D007275:Injections, Intravenous; D008236:Lypressin; D008297:Male; D008875:Middle Aged; D011336:Pro... | Scandinavian journal of gastroenterology | 2,001 | D008236:Lypressin; D000077585:Terlipressin |
Delving deeper into the unexpected correlation between gene expressivity and codon usage bias of Escherichia coli genome. | Biased usage of synonymous codons has been elucidated under the perspective of cellular tRNA abundance and more recently by the mRNA secondary structure folding stability of the corresponding genes. Taking advantage of publicly available gene expression data for Escherichia coli, a comprehensive investigation of the th... | 10.1080/07391102.2008.10507212 | 18,399,699 | D003062:Codon; D004926:Escherichia coli; D015964:Gene Expression Regulation, Bacterial; D016680:Genome, Bacterial; D009690:Nucleic Acid Conformation; D012333:RNA, Messenger; D012343:RNA, Transfer | Journal of biomolecular structure & dynamics | 2,008 | D003062:Codon; D012333:RNA, Messenger; D012343:RNA, Transfer |
IFN-gamma promotes generation of IL-10 secreting CD4+ T cells that suppress generation of CD8 responses in an antigen-experienced host. | Ags characterizing tumors or chronic viral infection are generally presented to the host immune system before specific immunotherapy is initiated, and consequent generation of regulatory CD4(+) T cells can inhibit induction of desired effector CD8 T cell responses. IL-10 produced in response to ongoing Ag exposure inhi... | 10.4049/jimmunol.0802047 | 19,535,638 | D000818:Animals; D052688:Bovine papillomavirus 1; D015704:CD4 Antigens; D018414:CD8-Positive T-Lymphocytes; D036022:Capsid Proteins; D003602:Cytotoxicity, Immunologic; D005260:Female; D007165:Immunosuppression Therapy; D007371:Interferon-gamma; D016753:Interleukin-10; D053645:Interleukin-2 Receptor alpha Subunit; D0081... | Journal of immunology (Baltimore, Md. : 1950) | 2,009 | D015704:CD4 Antigens; D036022:Capsid Proteins; D053645:Interleukin-2 Receptor alpha Subunit; D018124:Receptors, Tumor Necrosis Factor; D016753:Interleukin-10; D007371:Interferon-gamma |
Haloperidol modulates noradrenergic responses to aversive stimulation depending on treatment duration. | Antipsychotic drugs are widely used in the treatment of schizophrenia. While their effects are considered to be due to a modulation of dopaminergic and serotonergic signaling, little is known about their effects on noradrenergic (NA) activity in the brain. In this study, rats received either a 6d or 14 d treatment with... | 10.1016/j.bbr.2011.03.011 | 21,396,963 | D000818:Animals; D001070:Appetitive Behavior; D002421:Caudate Nucleus; D004334:Drug Administration Schedule; D005106:Exploratory Behavior; D006220:Haloperidol; D015918:Infusion Pumps, Implantable; D017551:Microdialysis; D009638:Norepinephrine; D009714:Nucleus Accumbens; D010812:Physical Stimulation; D017397:Prefrontal ... | Behavioural brain research | 2,011 | D006220:Haloperidol; D009638:Norepinephrine |
Acute-on-chronic liver failure: Objective admission and support criteria in the intensive care unit. | Cirrhosis is a leading cause of morbidity and mortality throughout the world. Significant complications include variceal bleeding, hepatic encephalopathy, hepatorenal syndrome, and infection. When these complications are severe, admission to the intensive care unit (ICU) is often required for organ support and manageme... | 10.1016/j.jhepr.2019.02.005 | 32,039,351 | JHEP reports : innovation in hepatology | 2,019 | ||
[Demand for and the Development of Detection Techniques for Source of Schistosome Infection in China]. | Schistosomiasis is a type of zoonotic parasitosis that severely impairs human health. Rapid detection of infection sources is a key to the control of schistosomiasis. With the effective control of schistosomiasis in China, the detection techniques for infection sources have also been developed. The rate and the intensi... | 27,089,776 | D000818:Animals; D002681:China; D012547:Schistosoma; D012552:Schistosomiasis | Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases | 2,015 | ||
Metabolism of the reserve polysaccharide of Streptococcus mitior (mitis): is there a second alpha-1,4-glucan phosphorylase? | The alpha-1,4-glucan phosphorylase (alpha-1,4-glucan: orthophosphate glucosyltransferase; EC 2.4.1.1) associated with the particulate cell fraction of Streptococcus mitior strain S3 was compared with the soluble maltodextrin phosphorylase that had been previously isolated from the same organism (Walker et al., 1969). T... | 10.1128/jb.127.1.281-290.1976 | 6,434 | D006003:Glycogen; D006863:Hydrogen-Ion Concentration; D007527:Isoenzymes; D006005:Phosphorylases; D011135:Polysaccharides, Bacterial; D012995:Solubility; D013291:Streptococcus; D013347:Subcellular Fractions; D013696:Temperature | Journal of bacteriology | 1,976 | D007527:Isoenzymes; D011135:Polysaccharides, Bacterial; D006003:Glycogen; D006005:Phosphorylases |
Pax Vobiscum--a Swedish large PACS project. | The 'Pax Vobiscum' project aims to interlink the five radiology departments of the administrative region Orebro County into one virtual department. Altogether the 48 examination rooms, producing 185000 examinations per year, will convert to digital filmless technology and work as one functional unit although geographic... | 10.1016/s0169-2607(98)00042-x | 9,803,996 | D011872:Radiology Department, Hospital; D011873:Radiology Information Systems; D013548:Sweden | Computer methods and programs in biomedicine | 1,998 | |
Southland Hospital's experience with the Austin Moore hemiarthroplasty. | AIM
The assessment of hospital performance with reference to patients who receive Austin Moore hemiarthroplasty for neck of femur fractures and the assessment of patients at medium term follow up.
METHODS
A retrospective review of 103 Austin Moore hemiarthroplasties in 101 patients. This review spans an 11 year perio... | 7,753,515 | D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005265:Femoral Neck Fractures; D006622:Hip Prosthesis; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009520:New Zealand; D010043:Outcome and Process Assessment, Health Care; D012044:Regression Analysis; D012189:Retrospective Studies | The New Zealand medical journal | 1,995 | ||
Patterns and correlates of grip strength change with age in Afro-Caribbean men. | BACKGROUND
muscle strength is essential for physical functions and an indicator of morbidity and mortality in older adults. Among the factors associated with muscle strength loss with age, ethnicity has been shown to play an important role.
OBJECTIVE
to examine the patterns and correlates of muscle strength change wi... | 10.1093/ageing/afs030 | 22,465,797 | D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D044383:Black People; D001823:Body Composition; D015992:Body Mass Index; D018737:Hand Strength; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D018908:Muscle Weakness; D018570:Risk Assessment; ... | Age and ageing | 2,012 | |
Defining Neighborhood Boundaries for Urban Health Research in Developing Countries: A Case Study of Accra, Ghana. | The neighborhood has been used as a sampling unit for exploring variations in health outcomes. In a variety of studies census tracts or ZIP codes have been used as proxies for neighborhoods because the boundaries are pre-defined units for which other data are readily available. However these spatial units can be arbitr... | 10.1080/17445647.2013.765366 | 23,690,870 | Journal of maps | 2,013 | ||
Class-Aware Fully-Convolutional Gaussian and Poisson Denoising. | We propose a fully-convolutional neural-network architecture for image denoising which is simple yet powerful. Its structure allows to exploit the gradual nature of the denoising process, in which shallow layers handle local noise statistics, while deeper layers recover edges and enhance textures. Our method advances t... | 10.1109/TIP.2018.2859044 | 30,040,645 | IEEE transactions on image processing : a publication of the IEEE Signal Processing Society | 2,018 | ||
Transition Metal-Free Intermolecular C(sp2)-H Direct Amination of Furanones via a Redox Pathway. | A direct C(sp2)-H amination of 2-furanones under metal-free conditions was realized. This unprecedented intermolecular C-H to C-N conversion provides rapid access to 4-amino-furanone derivatives and novel aza-heterocycle fused furanone skeletons. A redox mechanism based on a double-Michael-addition intermediate INT2 is... | 10.1021/acs.joc.8b02760 | 30,607,949 | D000586:Amination; D002384:Catalysis; D005663:Furans; D010084:Oxidation-Reduction; D028561:Transition Elements | The Journal of organic chemistry | 2,019 | D005663:Furans; D028561:Transition Elements |
HIV infection in Poland (1985-96). | Reported numbers of HIV infections have provided an indication of the order of magnitude of the size of the HIV epidemic in Poland, and how it has evolved in time. To the end of 1996, most documented infections had been observed among intravenous drug users (IDUs, n=2, 933/3,470) and, to a lesser extent, men who have s... | 10,854,993 | D000163:Acquired Immunodeficiency Syndrome; D001727:Bisexuality; D002648:Child; D018563:Disease Notification; D004196:Disease Outbreaks; D005260:Female; D015658:HIV Infections; D020010:Heterosexuality; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D011044:Poland; D011159:Population Surveillance; D011477:Se... | Revue d'epidemiologie et de sante publique | 2,000 | ||
Mortality prediction model for patients with bladder urothelial tumor after radical cystectomy. | OBJECTIVE
Based on preoperative clinical and postoperative pathological variables, we aim to build a prediction model of cancer specific mortality (CSM) at 1, 3, and 5 years for patients with bladder transitional cell carcinoma treated with RC.
MATERIAL AND METHODS
Retrospective analysis of 517 patients with diagnosi... | 10.1016/j.acuro.2019.08.006 | 32,035,808 | D000368:Aged; D002295:Carcinoma, Transitional Cell; D015653:Cystectomy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors; D001749:Urinary Bladder Neoplasms | Actas urologicas espanolas | 2,020 | |
Autoimmune conditions and primary central nervous system lymphoma risk among older adults. | Primary central nervous system lymphoma (PCNSL) risk is highly increased in immunosuppressed individuals, such as those with human immunodeficiency virus infection and solid organ transplant recipients, but rates are increasing among immunocompetent older adults (age ≥65 years). We utilized data from a large, nationall... | 10.1111/bjh.16222 | 31,625,136 | D000368:Aged; D000369:Aged, 80 and over; D001327:Autoimmune Diseases; D016543:Central Nervous System Neoplasms; D005260:Female; D015658:HIV Infections; D015497:HIV-1; D006801:Humans; D007166:Immunosuppressive Agents; D008228:Lymphoma, Non-Hodgkin; D008297:Male; D012307:Risk Factors; D014481:United States | British journal of haematology | 2,020 | D007166:Immunosuppressive Agents |
Telemammography for breast cancer screening: a cost-effective approach in Argentina. | OBJECTIVES
Argentina is a low and middle-income country (LMIC) with a highly fragmented healthcare system that conflicts with access to healthcare stated by the country's Universal Health Coverage plan. A tele-mammography network could improve access to breast cancer screening decreasing its mortality. This research ai... | 10.1136/bmjhci-2021-100351 | 34,281,995 | D000328:Adult; D001118:Argentina; D001943:Breast Neoplasms; D000086382:COVID-19; D003362:Cost-Benefit Analysis; D055088:Early Detection of Cancer; D005260:Female; D006297:Health Services Accessibility; D006801:Humans; D008327:Mammography; D008490:Medical Informatics; D008875:Middle Aged; D019057:Quality-Adjusted Life Y... | BMJ health & care informatics | 2,021 | |
[The role of long-chain acyl-CoA in the disturbances of oxidative phosphorylation in the myocardium]. | The effect of intramitochondrial acyl-CoA on the respiration of rabbit heart mitochondria in different metabolic states was studied. Acyl-CoA inhibited O2 consumption by 11% in State 4 and by 6% in State 3. However, the effect of acyl-CoA was more pronounced (20%) in the intermediate state of respiration between State ... | 2,633,800 | D000214:Acyl Coenzyme A; D000244:Adenosine Diphosphate; D000818:Animals; D003402:Creatine Kinase; D007700:Kinetics; D008929:Mitochondria, Heart; D009206:Myocardium; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D011817:Rabbits | Biokhimiia (Moscow, Russia) | 1,989 | D000214:Acyl Coenzyme A; D000244:Adenosine Diphosphate; D003402:Creatine Kinase | |
A combined role of clinical nurse specialist and coordinator: optimizing continuity of care in an autologous bone marrow transplant program. | Bone marrow transplant patients pose challenges to achieving continuity of care, as they have complex needs, care is chronic, and patients cross numerous health care settings. Traditionally, bone marrow transplant centers have attempted to meet patient needs by separating needs into preadmission, inpatient, and outpati... | 10.1097/00002800-199401000-00016 | 8,299,067 | D016026:Bone Marrow Transplantation; D015400:Clinical Nursing Research; D003266:Continuity of Patient Care; D006801:Humans; D007587:Job Description; D008329:Managed Care Programs; D009720:Nurse Clinicians; D010353:Patient Education as Topic; D017009:Professional Autonomy; D012017:Referral and Consultation; D012380:Role | Clinical nurse specialist CNS | 1,994 | |
Treatment of pyelonephritis in adults. | Although prescribing an antibiotic for the treatment of pyelonephritis seems to be a relatively easy task, a close look at the available data is disturbing. Optimal therapies for the different clinical syndromes of pyelonephritis have not yet been defined. The high failure rate suggests that in pyelonephritis (bacteria... | 10.1016/s0025-7125(16)30060-8 | 7,752,732 | D000208:Acute Disease; D000328:Adult; D000465:Algorithms; D000900:Anti-Bacterial Agents; D001424:Bacterial Infections; D002908:Chronic Disease; D004352:Drug Resistance, Microbial; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011379:Prognosis; D011704:Pyelonephritis; D012008:Recurrence; D012... | The Medical clinics of North America | 1,995 | D000900:Anti-Bacterial Agents |
Cryo-sectioning and chemical-fixing ultramicrotomy techniques for imaging rubber latex particle morphology. | Two methods adapted from biological microscopy are described for a new application in imaging the morphology of rubbery latex particles. In the first method, a drop of latex is frozen in liquid nitrogen, sectioned with a diamond knife and vapour-stained with osmium tetroxide, then viewed by transmission electron micros... | 10.1002/jemt.20018 | 14,722,908 | D020285:Cryoelectron Microscopy; D016616:Cryoultramicrotomy; D005976:Glutaral; D020366:Methylmethacrylate; D008863:Microspheres; D009993:Osmium Tetroxide; D011108:Polymers; D012408:Rubber | Microscopy research and technique | 2,004 | D011108:Polymers; D020366:Methylmethacrylate; D012408:Rubber; D009993:Osmium Tetroxide; D005976:Glutaral |
Chromatin fragments containing bovine 1.715 g ml-1 satellite DNA. Purification by chromatography on malachite green DNA affinity resin. | Chromatin fragments containing bovine 1.715 g ml-1 satellite DNA (1.715 satellite chromatin) were purified in order to test for differences between satellite chromatin and unfractionated chromatin. The final purification procedure involved digestion of isolated nuclei with Eco RI restriction endonuclease, solubilizatio... | 6,288,699 | D000818:Animals; D002417:Cattle; D002467:Cell Nucleus; D002843:Chromatin; D002846:Chromatography, Affinity; D004396:Coloring Agents; D004262:DNA Restriction Enzymes; D004276:DNA, Satellite; D015246:Deoxyribonuclease EcoRI; D007668:Kidney; D008297:Male; D012394:Rosaniline Dyes; D013950:Thymus Gland | The Journal of biological chemistry | 1,982 | D002843:Chromatin; D004396:Coloring Agents; D004276:DNA, Satellite; D012394:Rosaniline Dyes; C005095:malachite green; D004262:DNA Restriction Enzymes; D015246:Deoxyribonuclease EcoRI | |
African trypanosome interactions with an in vitro model of the human blood-brain barrier. | The neurological manifestations of sleeping sickness in man are attributed to the penetration of the blood-brain barrier (BBB) and invasion of the central nervous system by Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense. However, how African trypanosomes cross the BBB remains an unresolved issue. We ha... | 10.1645/GE-287R | 15,562,595 | D000818:Animals; D001812:Blood-Brain Barrier; D002118:Calcium; D002460:Cell Line; D017097:Electric Impedance; D042783:Endothelial Cells; D006801:Humans; D066298:In Vitro Techniques; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D014162:Transfection... | The Journal of parasitology | 2,004 | D002118:Calcium |
Penicillin biosensor based on a capacitive field-effect structure functionalized with a dendrimer/carbon nanotube multilayer. | Silicon-based sensors incorporating biomolecules are advantageous for processing and possible biological recognition in a small, reliable and rugged manufactured device. In this study, we report on the functionalization of field-effect (bio-)chemical sensors with layer-by-layer (LbL) films containing single-walled carb... | 10.1016/j.bios.2009.07.007 | 19,651,505 | D015374:Biosensing Techniques; D050091:Dendrimers; D025802:Electric Capacitance; D004563:Electrochemistry; D004566:Electrodes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D036103:Nanotechnology; D037742:Nanotubes, Carbon; D010406:Penicillins; D014159:Transducers | Biosensors & bioelectronics | 2,009 | D050091:Dendrimers; D037742:Nanotubes, Carbon; D010406:Penicillins |
Development of the electroretinogram between 30 and 50 weeks after conception. | Maturation of the electroretinogram (ERG) reflects retinal development. Serial ERGs recorded from a preterm infant between 30 and 50 weeks after conception showed rapid maturation. A transient loss of retinal sensitivity coincided with clinical signs of stage 2 retinopathy of prematurity (ROP). | 10.1016/j.earlhumdev.2004.10.019 | 15,935,923 | D000367:Age Factors; D004596:Electroretinography; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D012160:Retina; D012178:Retinopathy of Prematurity | Early human development | 2,005 | |
Effects of d-amphetamine on short- and long-term memory in spontaneously hypertensive, Wistar-Kyoto and Sprague-Dawley rats. | Diverse studies indicate that the attention deficit hyperactivity disorder (ADHD) is associated with alterations in encoding processes, including working or short-term memory. Some ADHD dysfunctional domains are reflected in the spontaneously hypertensive rat (SHR). Here SHR-saline group showed significantly poor STM a... | 10.1016/j.bbr.2010.08.035 | 20,813,138 | D000661:Amphetamine; D000704:Analysis of Variance; D000818:Animals; D000697:Central Nervous System Stimulants; D008297:Male; D057567:Memory, Long-Term; D008570:Memory, Short-Term; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D017207:Rats, Sprague-Dawley; D013045:Species Specificity | Behavioural brain research | 2,011 | D000697:Central Nervous System Stimulants; D000661:Amphetamine |
Phylogenetic identification of Sparganum proliferum as a pseudophyllidean cestode by the sequence analyses on mitochondrial COI and nuclear sdhB genes. | Sparganum proliferum is a larval cestode for which the adult stage is unknown. It is characterized by the continuous branching and budding when parasitized to humans, and causes fatal human sparganosis. However, the biological features of S. proliferum, including its taxonomic status, still remain obscure. Our previous... | 10.1016/s1383-5769(01)00071-x | 11,438,431 | D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002589:Cestoda; D003001:Cloning, Molecular; D018509:DNA, Helminth; D004272:DNA, Mitochondrial; D003576:Electron Transport Complex IV; D017238:Genes, Helminth; D007506:Iron-Sulfur Proteins; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:P... | Parasitology international | 2,001 | D018509:DNA, Helminth; D004272:DNA, Mitochondrial; D007506:Iron-Sulfur Proteins; D021122:Protein Subunits; C108095:SDHB protein, human; D013385:Succinate Dehydrogenase; D003576:Electron Transport Complex IV |
The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation. | PknB is a transmembrane Ser/Thr protein kinase that defines and belongs to an ultraconserved kinase subfamily found in Gram-positive bacteria. Essential for Mycobacterium tuberculosis growth, its close homolog in Bacillus subtilis has been linked to exit from dormancy. The kinase possesses an extracellular region compo... | 10.1016/j.str.2010.02.013 | 20,462,494 | D019281:Dimerization; D004789:Enzyme Activation; D008024:Ligands; D008958:Models, Molecular; D009169:Mycobacterium tuberculosis; D010770:Phosphotransferases; D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases; D017434:Protein Structure, Tertiary; D015398:Signal Transduction | Structure (London, England : 1993) | 2,010 | D008024:Ligands; D010770:Phosphotransferases; D011494:Protein Kinases; C475060:PknB protein, Mycobacterium tuberculosis; D017346:Protein Serine-Threonine Kinases |
Outcome at ages 1, 3, and 5 years of children born to diabetic women. | A prospective study of infants born to women with diabetes mellitus is reported. The children were examined at birth and followed at 1, 3, and 5 years of age. Medical and psychological information was obtained through follow-up examinations. Intrauterine growth was atypical and there was an increase in neonatal problem... | 10.1016/0002-9378(77)90499-9 | 835,641 | D000096:Acetone; D000367:Age Factors; D002675:Child, Preschool; D000013:Congenital Abnormalities; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D007236:Infant, Small for Gestational Age; D008607:Intellectual Disability; D007484:Iow... | American journal of obstetrics and gynecology | 1,977 | D000096:Acetone |
Nitrobenzylthioinosine (NBMPR) binding and nucleoside transporter ENT1 mRNA expression after prolonged wakefulness and recovery sleep in the cortex and basal forebrain of rat. | We have previously shown that extracellular adenosine levels increase locally in the basal forebrain (BF) during prolonged wakefulness, yet the cellular mechanisms of this local accumulation have remained unknown. The extracellular adenosine levels are strictly regulated by adenosine metabolism and its transport throug... | 10.1046/j.0962-1105.2003.00372.x | 14,633,241 | D000241:Adenosine; D000818:Animals; D001665:Binding Sites; D002540:Cerebral Cortex; D002940:Circadian Rhythm; D046508:Culture Techniques; D033721:Equilibrative Nucleoside Transporter 1; D017403:In Situ Hybridization; D008297:Male; D016548:Prosencephalon; D012333:RNA, Messenger; D051381:Rats; D017208:Rats, Wistar; D0201... | Journal of sleep research | 2,003 | D033721:Equilibrative Nucleoside Transporter 1; D012333:RNA, Messenger; C438652:Slc29a1 protein, rat; D013868:Thioinosine; C001789:4-nitrobenzylthioinosine; D000241:Adenosine |
Amelioration of pregnancy-associated osteoporosis after treatment with vitamin K₂: a report of four patients. | Abstract We demonstrate for the first time therapeutic effects of vitamin K₂ (menatetrenone) on pregnancy-associated osteoporosis with multiple vertebral fractures in four cases. Due to its safety, vitamin K₂ presents itself as a treatment option for women with pregnancy-associated osteoporosis. Desirably, future contr... | 10.3109/03009734.2012.676573 | 22,746,299 | D000328:Adult; D005260:Female; D006801:Humans; D010024:Osteoporosis; D011247:Pregnancy; D011248:Pregnancy Complications; D024482:Vitamin K 2 | Upsala journal of medical sciences | 2,012 | D024482:Vitamin K 2 |
The distribution of Pasteurella haemolytica serotypes among cattle, sheep, and goats in South Africa and their association with diseases. | Over an 8-year period (September 1986 to March 1994), a total of 497 organ specimens from sheep and goats and 96 from cattle, were received for their isolation of Pasteurella haemolytica. They were collected in seven geographical areas in South Africa (as it existed before the April 1994 elections). These areas include... | 8,668,319 | D000818:Animals; D002417:Cattle; D002418:Cattle Diseases; D015511:Goat Diseases; D006041:Goats; D016978:Mannheimia haemolytica; D010326:Pasteurella Infections; D012703:Serotyping; D012756:Sheep; D012757:Sheep Diseases; D013019:South Africa | The Onderstepoort journal of veterinary research | 1,995 | ||
Dental pain in children with intellectual disabilities: caregivers' perspective. | Purpose. Description of pain is generally difficult in children, and more so in those with intellectual disabilities (ID). Aim. This study is aimed at evaluating dental pain from caregivers' perspective in children with ID. Methods. The study sampled 86 children (33 with ID, 53 normally developing) ages ranges from bir... | 10.1155/2012/701608 | 22,927,854 | International journal of dentistry | 2,012 | ||
Egg yolk antibodies for passive immunity. | The avian egg contains all of the necessary nutrients and growth factors required for the developing embryo, including antibodies that are transported from the blood of the hen into the egg yolk to provide immunity to the chick. Since the discovery of egg yolk antibodies, now called immunoglobulin Y (IgY), in the late ... | 10.1146/annurev-food-022811-101137 | 22,136,128 | D000818:Animals; D030161:Avian Proteins; D002645:Chickens; D004530:Egg Yolk; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007136:Immunoglobulins | Annual review of food science and technology | 2,012 | D030161:Avian Proteins; C016512:IgY; D007136:Immunoglobulins |
[Occupational cancer in criminal law]. | This paper addresses the issue of occupational cancer and criminal law with respect to: 1) causal links between occupation and cancer; 2) certainty and probability in causal links; 3) occupational and non occupational causes of cancer; 4) cancer predictability and employer behaviour. | 10,730,471 | D006801:Humans; D007558:Italy; D016365:Liability, Legal; D009369:Neoplasms; D009784:Occupational Diseases | Epidemiologia e prevenzione | 1,999 | ||
Distribution of thiophene derivatives in different organs of Tagetes patula seedlings grown under various conditions. | An intensive accumulation of thiophene derivatives occurs during the first days of development in Tagetes seedlings. After that, the thiophene content (related to dry weight) decreases to reach low values until the twelfth day of growth. High performance liquid chromatography analyses performed on cotyledons, on hypoco... | 10.1007/BF00392777 | 24,272,733 | Planta | 1,982 | ||
Click chemistry step growth polymerization of novel alpha-azide-omega-alkyne monomers. | A novel step growth polymerization A-B strategy based on the click chemistry polyaddition of tailor-made alpha-azide-omega-alkyne low molar mass monomers was developed, leading to polytriazole (co)polymers with tunable structures and properties. | 10.1039/b805164j | 18,802,508 | D000480:Alkynes; D001386:Azides; D002152:Calorimetry, Differential Scanning; D009682:Magnetic Resonance Spectroscopy; D011108:Polymers | Chemical communications (Cambridge, England) | 2,008 | D000480:Alkynes; D001386:Azides; D011108:Polymers |
CMOS tunable-wavelength multi-color photogate sensor. | A CMOS tunable-wavelength multi-color photogate (CPG) sensor is presented. Sensing of a small set of well-separated wavelengths (e.g., > 50 nm apart) is achieved by tuning the spectral response of the device with a bias voltage. The CPG employs the polysilicon gate as an optical filter, which eliminates the need for an... | 10.1109/TBCAS.2013.2243727 | 24,473,545 | D004867:Equipment Design; D005456:Fluorescent Dyes; D007091:Image Processing, Computer-Assisted; D045663:Quantum Dots; D012666:Semiconductors; D059629:Signal-To-Noise Ratio; D013050:Spectrometry, Fluorescence | IEEE transactions on biomedical circuits and systems | 2,013 | D005456:Fluorescent Dyes |
Cytokine transcription in lymph nodes of cattle in different stages of bovine leukemia virus infection. | Bovine leukemia virus (BLV) is a transforming oncovirus that contains no oncogenes or preferred site of proviral integration. The role of cytokines in the disease process of BLV is potentially important due to the similarity of BLV with other retroviruses in which cytokines play a role, such as HTLV-I and -II. Mesenter... | 10.1016/s0165-2427(97)00083-4 | 9,477,477 | D000199:Actins; D000818:Animals; D002417:Cattle; D016207:Cytokines; D016583:Enzootic Bovine Leukosis; D016370:Gene Products, rex; D016356:Gene Products, tax; D001909:Leukemia Virus, Bovine; D008198:Lymph Nodes; D012333:RNA, Messenger; D013601:T-Lymphocytes; D014158:Transcription, Genetic | Veterinary immunology and immunopathology | 1,997 | D000199:Actins; D016207:Cytokines; D016370:Gene Products, rex; D016356:Gene Products, tax; D012333:RNA, Messenger |
Aerobic exercise alleviates ischemia-induced memory impairment by enhancing cell proliferation and suppressing neuronal apoptosis in hippocampus. | PURPOSE
Neurogenic lower urinary tract dysfunction (NLUTD) is a possible consequence of several neurological disorders. NLUTD may produce debilitating symptoms and serious complications, such as chronic renal failure, and recurrent urinary tract infections. Many animal studies of NLUTD symptoms have focused on animal m... | 10.5213/inj.2014.18.4.187 | 25,562,035 | International neurourology journal | 2,014 | ||
Sweep pattern visual evoked potential acuity in children during their periods of visual development. | PURPOSE
To study the clinical usage of sweep pattern visual evoked potential (SPVEP) acuity in children's visual development periods and compare the amplitude-spatial frequency (A-SP) function regression method with the amplitude-logarithm of the visual angle (A-logVA) function regression method in evaluating the SPVEP... | 10.1159/000329866 | 21,811,053 | D000550:Amblyopia; D002648:Child; D002675:Child, Preschool; D005074:Evoked Potentials, Visual; D005123:Eye; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D008297:Male; D012030:Refractive Errors; D013285:Strabismus; D014786:Vision Disorders; D014792:Visual Acuity; D014793:Visual Cortex | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde | 2,011 | |
Utility of modular implants in primary total hip arthroplasty. | Most surgeons believe that some level of modularity has a valuable role to play in primary total hip arthroplasty. However, all modular junctions carry some risk and recent problems with taper tribocorrosion have elevated concerns. These problems suggest that more rigorous preclinical testing should be undertaken befor... | 24,655,609 | D019644:Arthroplasty, Replacement, Hip; D001696:Biomechanical Phenomena; D006622:Hip Prosthesis; D006801:Humans; D011474:Prosthesis Design | The Journal of arthroplasty | 2,014 | ||
Repressions of actin assembly and RhoA localization are involved in inhibition of tumor cell motility by lipophilic ascorbyl phosphate. | Our previous study showed that tumor invasion of human fibrosarcoma cells HT-1080 is hardly inhibited by ascorbic acid itself (Asc), but inhibited by 2-O-phosphorylated Asc-6-O-palmitylester (Asc2P6Plm) more markedly than 2-O-phosphorylated Asc or Asc-6-O-palmitylester, and that the inhibitory effect may be attributed ... | 14,612,927 | D000199:Actins; D001205:Ascorbic Acid; D015153:Blotting, Western; D045744:Cell Line, Tumor; D002465:Cell Movement; D003497:Cyclic N-Oxides; D004305:Dose-Response Relationship, Drug; D004578:Electron Spin Resonance Spectroscopy; D006801:Humans; D017665:Hydroxyl Radical; D007150:Immunohistochemistry; D008856:Microscopy, ... | International journal of oncology | 2,003 | C403966:6-O-palmitol-ascorbate-2-O-phosphate; D000199:Actins; D003497:Cyclic N-Oxides; D017382:Reactive Oxygen Species; D013113:Spin Labels; C011669:ascorbate-2-phosphate; D017665:Hydroxyl Radical; C017245:5,5-dimethyl-1-pyrroline-1-oxide; D020742:rhoA GTP-Binding Protein; D001205:Ascorbic Acid | |
Is playing video games related to cognitive abilities? | The relations between video-game experience and cognitive abilities were examined in the current study. In two experiments, subjects performed a number of working memory, fluid intelligence, and attention-control measures and filled out a questionnaire about their video-game experience. In Experiment 1, an extreme-grou... | 10.1177/0956797615570367 | 25,896,420 | D000293:Adolescent; D000328:Adult; D001076:Aptitude; D001288:Attention; D003071:Cognition; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D008570:Memory, Short-Term; D011795:Surveys and Questionnaires; D018910:Video Games; D055815:Young Adult | Psychological science | 2,015 | |
Safety evaluations and lipid-lowering activity of an Arthrospira platensis enriched diet: A 1-month study in rats. | Arthrospira platensis (A. platensis) is worldwide consumed as dietary supplement, but its use in the form of whole biomass for food purposes may raise toxicity concerns. The aim of this study was to preliminarily evaluate the safety of an A. platensis F&M-C256-enriched diet (20% (weight/weight) corresponding to 12g/kg ... | 10.1016/j.foodres.2017.09.011 | 29,195,962 | D000821:Animal Feed; D000818:Animals; D015415:Biomarkers; D008076:Cholesterol, HDL; D005243:Feces; D008055:Lipids; D008099:Liver; D008297:Male; D047493:PPAR alpha; D019936:Probiotics; D017207:Rats, Sprague-Dawley; D018570:Risk Assessment; D053545:Spirulina; D013997:Time Factors; D014280:Triglycerides | Food research international (Ottawa, Ont.) | 2,017 | D015415:Biomarkers; D008076:Cholesterol, HDL; D008055:Lipids; D047493:PPAR alpha; D014280:Triglycerides |
[Changes in the dynamic surface tension of urine in lupiform glomerulonephritis]. | As many as 54 patients with systemic lupus erythematosis presenting with the kidney damage and thirteen damage-free patients were studied for the dynamic surface tension (ST) of the urine with the aid of the computerized tensiometer MPT2. The condition is characterized by a drop in ST with the surface time equal to 1 s... | 11,692,733 | D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D005921:Glomerulonephritis; D006801:Humans; D008180:Lupus Erythematosus, Systemic; D008297:Male; D008875:Middle Aged; D013500:Surface Tension | Likars'ka sprava | 2,001 | ||
Distance determination in human ubiquitin by pulsed double electron-electron resonance and double quantum coherence ESR methods. | Recently, distance measurements by pulsed ESR (electron spin resonance) have been obtained using pulsed DEER (double electron-electron resonance) and DQC (double quantum coherence) in SDSL (site directed spin labeling) proteins. These methods can observe long range dipole interactions (15-80A). We applied these methods... | 10.1016/j.jmr.2006.09.017 | 17,046,296 | D000465:Algorithms; D003461:Crystallography; D004583:Electrons; D006801:Humans; D011487:Protein Conformation; D011789:Quantum Theory; D012815:Signal Processing, Computer-Assisted; D013113:Spin Labels; D025801:Ubiquitin | Journal of magnetic resonance (San Diego, Calif. : 1997) | 2,007 | D013113:Spin Labels; D025801:Ubiquitin |
Giardia and other intestinal parasites in dogs from veterinary clinics in Japan. | The present study is the first report that describes the national survey of intestinal parasites in private household dogs brought to veterinary clinics in Japan. A total of 2,365 fresh feces were collected. Giardia-specific coproantigen was examined by ELISA kit (SNAP(®) Giardia, IDEXX Laboratories, Inc.; Maine, USA).... | 10.1007/s00436-011-2258-y | 21,279,384 | D000818:Animals; D004283:Dog Diseases; D004285:Dogs; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces; D006762:Hospitals, Animal; D007411:Intestinal Diseases, Parasitic; D007564:Japan; D008853:Microscopy; D010271:Parasites; D015995:Prevalence | Parasitology research | 2,011 | |
Cutting Procedures, Tensile Testing, and Ageing of Flexible Unidirectional Composite Laminates. | Many body armor designs incorporate unidirectional (UD) laminates. UD laminates are constructed of thin (<0.05 mm) layers of high-performance yarns, where the yarns in each layer are oriented parallel to each other and held in place using binder resins and thin polymer films. The armor is constructed by stacking the un... | 10.3791/58991 | 31,081,808 | D008422:Materials Testing; D011108:Polymers; D013314:Stress, Mechanical; D013718:Tensile Strength | Journal of visualized experiments : JoVE | 2,019 | D011108:Polymers |
Primary breast lymphoma: A single-centre experience. | BACKGROUND
Primary non-Hodgkin lymphoma is an extremely rare entity, and this condition represents less than 0.5% of all malignant lesions involving the mammary gland. As such, there has been a paucity of relevant clinical data arising from Southeast Asia.
AIMS
Our study aims to review the clinical presentation, diag... | 10.1002/cnr2.1140 | 32,721,093 | D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D001943:Breast Neoplasms; D003520:Cyclophosphamide; D018572:Disease-Free Survival; D004317:Doxorubicin; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse; D008875:Middle Aged; D009367:Neoplasm Staging; D011241:Pre... | Cancer reports (Hoboken, N.J.) | 2,019 | C571759:R-CHOP protocol; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone |
Intermittent left bundle branch block in the athletic heart syndrome. | A 30-year-old man with typical findings of the athletic heart syndrome is presented because of the unique feature of intermittent left bundle branch block. Observations during right atrial pacing and exercise support the concept of autonomic control of intraventricular conduction, both adrenergic and cholinergic. | 10.1378/chest.71.6.776 | 140,790 | D000328:Adult; D001341:Autonomic Nervous System; D002037:Bundle-Branch Block; D006332:Cardiomegaly; D004562:Electrocardiography; D006329:Heart Conduction System; D006801:Humans; D008297:Male; D013178:Sports Medicine; D013577:Syndrome | Chest | 1,977 | |
Reproductive effects of prenatal exposure to 5-bromo-2'-deoxyuridine on male rats. | 5-Bromo-2'-deoxyuridine (BrdU) was administered intraperitoneally to Sprague-Dawley rats at doses of 12.5, 25, 50, or 100 mg/kg/d on days 9 through 15 of gestation, and at 50 or 100 mg/kg/d on days 16 through 20 of gestation. Dams were allowed to deliver naturally and the numbers of live and dead pups were recorded. Ma... | 10.1016/s0890-6238(96)00195-5 | 9,138,632 | D000818:Animals; D001921:Brain; D001973:Bromodeoxyuridine; D004822:Epididymis; D005260:Female; D005298:Fertility; D007274:Injections, Intraperitoneal; D008297:Male; D009929:Organ Size; D010902:Pituitary Gland; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D012... | Reproductive toxicology (Elmsford, N.Y.) | 1,997 | D001973:Bromodeoxyuridine |
Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer. | BACKGROUND
Standard therapy for metastatic non small cell lung cancer (NSCLC) includes palliative systemic chemotherapy and/or radiotherapy. Recent studies of patients with limited metastases treated with curative-intent stereotactic body radiation therapy (SBRT) have shown encouraging survival. We hypothesized that pa... | 10.1186/1748-717X-6-80 | 21,718,501 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung; D005260:Female; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D010166:Palliative Care; D011878:Radiotherapy; D012008:Recurrence; D012189:Ret... | Radiation oncology (London, England) | 2,011 | |
Changes in retinal alphaB-crystallin (cryab) RNA transcript levels during periods of altered ocular growth in chickens. | Changes in retinal crystallin gene expression have been implicated in the development of myopia in animal models. We therefore investigated the expression of alphaB-crystallin (cryab) in the chicken retina during periods of increased ocular growth induced by form-deprivation and negative lens-wear, and during periods o... | 10.1016/j.exer.2009.10.011 | 19,878,675 | D000818:Animals; D000831:Animals, Newborn; D002645:Chickens; D004195:Disease Models, Animal; D005123:Eye; D005786:Gene Expression Regulation; D008297:Male; D009216:Myopia; D012322:RNA Precursors; D012160:Retina; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012683:Sensory Deprivation; D038203:alpha-Crystall... | Experimental eye research | 2,010 | D012322:RNA Precursors; D038203:alpha-Crystallin B Chain |
Greatly improved neuroprotective efficiency of citicoline by stereotactic delivery in treatment of ischemic injury. | Limited penetration of neuroprotective drug citicoline into the central nervous system (CNS) by systemic administration led to poor efficiency. A novel method of stereotactic drug delivery was explored to make citicoline bypass the blood brain barrier (BBB) and take effect by direct contact with ischemic neurons. A per... | 10.3109/10717544.2011.589084 | 21,923,252 | D000818:Animals; D001522:Behavior, Animal; D001812:Blood-Brain Barrier; D002545:Brain Ischemia; D003566:Cytidine Diphosphate Choline; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D016503:Drug Delivery Systems; D020244:Infarction, Middle Cerebral Artery; D008279:Magnetic Resonance Imaging; D... | Drug delivery | 2,011 | D018696:Neuroprotective Agents; D018697:Nootropic Agents; D003566:Cytidine Diphosphate Choline |
Parasite burden in a short-lived chameleon, Furcifer labordi. | Life history theory predicts that species with shorter lifespan should show higher investments into growth and reproduction at the expense of immune defenses. Labord's chameleon (Furcifer labordi) is the tetrapod with the shortest known life span. To investigate to which extent immunosenescence influences the die-off o... | 10.1016/j.ijppaw.2019.09.010 | 31,667,086 | International journal for parasitology. Parasites and wildlife | 2,019 | ||
Identification of Salmonella Typhimurium Deubiquitinase SseL Substrates by Immunoaffinity Enrichment and Quantitative Proteomic Analysis. | Ubiquitination is a key protein post-translational modification that regulates many important cellular pathways and whose levels are regulated by equilibrium between the activities of ubiquitin ligases and deubiquitinases. Here, we present a method to identify specific deubiquitinase substrates based on treatment of ce... | 10.1021/acs.jproteome.5b00574 | 26,147,956 | D000818:Animals; D001426:Bacterial Proteins; D002460:Cell Line; D007118:Immunoassay; D013058:Mass Spectrometry; D051379:Mice; D025941:Protein Interaction Mapping; D011499:Protein Processing, Post-Translational; D040901:Proteomics; D012486:Salmonella typhimurium; D064570:Ubiquitin-Specific Proteases; D054875:Ubiquitinat... | Journal of proteome research | 2,015 | D001426:Bacterial Proteins; D064570:Ubiquitin-Specific Proteases |
Effects of 5-aminolevulinic acid supplementation on milk production, iron status, and immune response of dairy cows. | The objective of this study was to investigate the effect of 5-aminolevulinic acid (5-ALA) as a dietary supplement on milk yield and composition as well as iron status and immune response in lactating dairy cows. In this study 13 lactating Holstein cows were randomly assigned to either a control group or a treatment gr... | 10.3168/jds.2018-15982 | 31,587,902 | D000622:Aminolevulinic Acid; D000821:Animal Feed; D000818:Animals; D002417:Cattle; D018592:Cross-Over Studies; D003612:Dairying; D004032:Diet; D019587:Dietary Supplements; D005260:Female; D007109:Immunity; D007501:Iron; D007774:Lactation; D007785:Lactose; D008892:Milk; D008894:Milk Proteins | Journal of dairy science | 2,019 | D008894:Milk Proteins; D000622:Aminolevulinic Acid; D007501:Iron; D007785:Lactose |
Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence. | To maintain tissue homeostasis, cells transition between cell cycle quiescence and proliferation. An essential G1 process is minichromosome maintenance complex (MCM) loading at DNA replication origins to prepare for S phase, known as origin licensing. A p53-dependent origin licensing checkpoint normally ensures suffici... | 10.1083/jcb.201902143 | 31,186,278 | D048868:Adaptor Proteins, Signal Transducing; D002453:Cell Cycle; D018797:Cell Cycle Proteins; D002455:Cell Division; D002467:Cell Nucleus; D049109:Cell Proliferation; D002843:Chromatin; D004261:DNA Replication; D005434:Flow Cytometry; D016193:G1 Phase; D042822:Genomic Instability; D006801:Humans; D009687:Nuclear Prote... | The Journal of cell biology | 2,019 | D048868:Adaptor Proteins, Signal Transducing; D018797:Cell Cycle Proteins; D002843:Chromatin; C519407:MCMBP protein, human; D009687:Nuclear Proteins |
A 2D/3D matching based on a hybrid approach: improvement to the imaging flow for AVM radiosurgery. | A new approach of registration in multimodal imaging has been developed. Modalities involved are Digital Subtracted Angiography (DSA, 2D) and Magnetic Resonance Angiography (MRA, 3D). Our approach is an hybrid one, mixing feature and intensity based approaches. This approach is based on the extraction of a anatomical r... | 10.1109/IEMBS.2005.1617123 | 17,282,892 | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference | 2,005 | ||
What effect does glucose have on measured creatinine in the peritoneal equilibration test? | Very high glucose concentrations falsely elevate measured creatinine. An appropriate correction factor may be applied to obtain an accurate creatinine value; however, the glucose interference is of a low magnitude in most dialysate samples at a 4-hour dwell time. Clinical interpretation of the peritoneal equilibration ... | 2,025,055 | D003124:Colorimetry; D003404:Creatinine; D015314:Dialysis Solutions; D005947:Glucose; D006801:Humans; D010530:Peritoneal Dialysis | ANNA journal | 1,991 | D015314:Dialysis Solutions; D003404:Creatinine; D005947:Glucose | |
A comparison of the efficacy and tolerability of two recombinant human follicle-stimulating hormone preparations in patients undergoing in vitro fertilization-embryo transfer. | OBJECTIVE
To compare the efficacy and tolerability of two recombinant human FSH (r-hFSH) preparations, follitropin-alpha (Gonal-F; Ares Serono, Geneva, Switzerland) and follitropin-beta (Puregon; Organon, Oss, the Netherlands), for superovulation in patients undergoing IVF-ET.
DESIGN
Randomized, parallel-group, asses... | 10.1016/s0015-0282(99)00450-1 | 10,632,423 | D000293:Adolescent; D000328:Adult; D002064:Buserelin; D006063:Chorionic Gonadotropin; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone; D037201:Follicle Stimulating Hormone, beta Subunit; D015292:Glycoprotein Hormones, alpha Subunit; D006801:Humans; D007247:I... | Fertility and sterility | 2,000 | D006063:Chorionic Gonadotropin; D037201:Follicle Stimulating Hormone, beta Subunit; D015292:Glycoprotein Hormones, alpha Subunit; D011994:Recombinant Proteins; D005640:Follicle Stimulating Hormone; D002064:Buserelin |
Evaluation of nutrient loads from a mountain forest including storm runoff loads. | Water quality and flow rates at a weir installed on the end of Aburahi-S Experimental Watershed (3.34 ha) were measured once a week from 2001 to 2003 and in appropriate intervals from 30 min to 6 h during five storm runoff events caused by each rainfall from 8 mm to 417 mm. The average annual loads of total nitrogen (T... | 10.2166/wst.2006.041 | 16,594,326 | D001272:Atmosphere; D004777:Environment; D004784:Environmental Monitoring; D005069:Evaluation Studies as Topic; D007564:Japan; D009584:Nitrogen; D010758:Phosphorus; D011891:Rain; D015203:Reproducibility of Results; D013997:Time Factors; D014197:Trees; D014867:Water; D014872:Water Movements; D014881:Water Supply | Water science and technology : a journal of the International Association on Water Pollution Research | 2,006 | D014867:Water; D010758:Phosphorus; D009584:Nitrogen |
Irony and empathy in children with traumatic brain injury. | Social communication involves influencing what other people think and feel about themselves. We use the term conative theory of mind (ToM) to refer to communicative interactions involving one person trying to influence the mental and emotional state of another, paradigmatic examples of which are irony and empathy. This... | 10.1017/S1355617712001440 | 23,331,976 | D000293:Adolescent; D001930:Brain Injuries; D016022:Case-Control Studies; D002648:Child; D003072:Cognition Disorders; D003469:Culture; D004645:Empathy; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D016015:Logistic Models; D008297:Male; D011939:Mental Recall; D009341:Negativism; D009483:Neuropsychological... | Journal of the International Neuropsychological Society : JINS | 2,013 | |
[Activation of Langat virus infection in mice under the influence of Licopid]. | The impact of Licopid and purified staphylococcal toxoid on the development of neurovirus infection caused by Langat virus was experimentally studied with mice as a model. The prophylactic (prior to infection) use of licopid was found to activate the infection. In the population of macrophages of different localization... | 15,636,143 | D000119:Acetylmuramyl-Alanyl-Isoglutamine; D000276:Adjuvants, Immunologic; D000818:Animals; D002448:Cell Adhesion; D004195:Disease Models, Animal; D004669:Encephalitis Viruses, Tick-Borne; D004675:Encephalitis, Tick-Borne; D008264:Macrophages; D051379:Mice; D008807:Mice, Inbred BALB C; D013154:Spleen; D014775:Virus Act... | Zhurnal mikrobiologii, epidemiologii i immunobiologii | 2,004 | D000276:Adjuvants, Immunologic; D000119:Acetylmuramyl-Alanyl-Isoglutamine | |
Accessibility and characteristics of memories of the future. | Recent research suggests that some imagined future events are encoded in memory, leading to the formation of "memories of the future". However, questions remain regarding the exact components of future event simulations that are encoded and the factors that determine their accessibility. To address these questions, the... | 10.1080/09658211.2016.1205096 | 27,396,758 | D000293:Adolescent; D000328:Adult; D004644:Emotions; D005260:Female; D006040:Goals; D006801:Humans; D007092:Imagination; D008297:Male; D061212:Memory, Episodic; D021641:Recognition, Psychology; D055815:Young Adult | Memory (Hove, England) | 2,017 | |
Positive correlation of serum adipocyte fatty acid binding protein levels with metabolic syndrome in kidney transplantation patients. | Adipocyte fatty acid binding protein (A-FABP) is significantly expressed in white and brown adipose tissue, monocytes, and macrophages and is a central regulator of systemic insulin sensitivity. Metabolic syndrome (MetS) is a risk factor for post-transplant diabetes mellitus (PTDM), chronic graft dysfunction, graft los... | 31,966,732 | International journal of clinical and experimental pathology | 2,017 | |||
Fetal heart rate monitoring device using condenser microphone sensor: Validation and comparison to standard devices. | BACKGROUND
Fetal heart rate (FHR) monitoring device is highly demanded to assess the fetus health condition in home environments. Conventional standard devices such as ultrasonography and cardiotocography are expensive, bulky and uncomfortable and consequently not suitable for long-term monitoring. Herein, we report a ... | 10.3233/THC-171067 | 29,758,955 | D005260:Female; D005323:Fetal Monitoring; D006340:Heart Rate, Fetal; D006801:Humans; D007091:Image Processing, Computer-Assisted; D011247:Pregnancy; D015203:Reproducibility of Results | Technology and health care : official journal of the European Society for Engineering and Medicine | 2,018 | |
Correction to: Clinical and economic effects of an antimicrobial stewardship intervention in a surgical intensive care unit. | The original version of this article unfortunately contained a mistake. | 10.1007/s15010-020-01447-y | 32,435,991 | Infection | 2,020 | ||
Genistein Suppresses v-Src-Driven Proliferative Activity by Arresting the Cell-Cycle at G2/M through Increasing p21 Level in Src-Activated Human Gallbladder Carcinoma cells. | Activated Src have been strongly implicated in the development, progression, and metastasis of many human cancers. Although soy isoflavones exhibit potential anticancer activity, effects of isoflavones on oncogenic activity of Src remains unknown. Using v-src-transfected human adenocarcinoma cells (HAG/src3-1), we inve... | 10.1080/01635581.2020.1797835 | 32,705,888 | D017209:Apoptosis; D002453:Cell Cycle; D060754:Equol; D005706:Gallbladder Neoplasms; D019833:Genistein; D006801:Humans; D007529:Isoflavones | Nutrition and cancer | 2,021 | D007529:Isoflavones; D060754:Equol; D019833:Genistein |
Implications for research and clinical use from a Rasch analysis of the HOOS-12 and KOOS-12 instruments. | OBJECTIVE
To evaluate the structural validity of the 12-item Hip disability and Osteoarthritis Outcome Score (HOOS-12) and 12-item Knee injury and Osteoarthritis Outcome Score (KOOS-12) using Rasch analysis and consider psychometric implications for research and clinical use.
METHOD
Individual-level HOOS-12 and KOOS-... | 10.1016/j.joca.2021.02.568 | 33,676,016 | D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D035843:Biomedical Research; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip; D020370:Osteoarthritis, Knee; D000071066:Patient Reported Outcome Measures; D057566:Self Report | Osteoarthritis and cartilage | 2,021 | |
Changes in the gene expression profile during spontaneous migraine attacks. | Migraine attacks are delimited, allowing investigation of changes during and outside attack. Gene expression fluctuates according to environmental and endogenous events and therefore, we hypothesized that changes in RNA expression during and outside a spontaneous migraine attack exist which are specific to migraine. Tw... | 10.1038/s41598-021-87503-5 | 33,859,262 | D000293:Adolescent; D000328:Adult; D000368:Aged; D004843:Epistasis, Genetic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders; D012313:RNA; D018170:Sumatriptan; D059467:Transcriptome; D055815:Young Adult | Scientific reports | 2,021 | D012313:RNA; D018170:Sumatriptan |
Problems with interpreting troponins in chronic kidney disease patients for ruling out acute coronary syndrome. | Chest pain is one of the most common reasons for emergency department visits worldwide, and troponins play a central role in diagnosing acute coronary syndrome (ACS) in these patients. Hence, the tests for these molecules are imperative in triage for ACS. Presently, multiple high-sensitivity troponin tests are availabl... | 10.1016/j.ajem.2020.12.051 | 33,378,716 | D054058:Acute Coronary Syndrome; D006801:Humans; D051436:Renal Insufficiency, Chronic; D012680:Sensitivity and Specificity; D019210:Troponin I; D020107:Troponin T | The American journal of emergency medicine | 2,021 | D019210:Troponin I; D020107:Troponin T |
Identification of DNA methylation differences during tumorigenesis by methylation-sensitive arbitrarily primed polymerase chain reaction. | The ability to detect methylation changes associated with oncogenic transformation is of critical importance in understanding how DNA methylation may contribute to tumorigenesis. We have developed a simple and reproducible fingerprinting method called methylation-sensitive arbitrarily primed polymerase chain reaction (... | 10.1016/s1046-2023(02)00068-3 | 12,095,274 | D015139:Blotting, Southern; D002471:Cell Transformation, Neoplastic; D003110:Colonic Neoplasms; D018899:CpG Islands; D019175:DNA Methylation; D017931:DNA Primers; D004273:DNA, Neoplasm; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D014407:Tumor Cells, Cultured | Methods (San Diego, Calif.) | 2,002 | D017931:DNA Primers; D004273:DNA, Neoplasm |
Refractory migraine: the role of the physician in assessment and treatment of a problematic disease. | Patients affected by chronic forms of headache are often very difficult to treat. Refractory patients are so defined when adequate trials of specific drugs (for acute or prophylactic treatment) failed both to reduce the burden of disease and to improve headache-related quality of life. An escalating approach is suggest... | 10.1007/s10072-013-1385-x | 23,695,056 | D006801:Humans; D008881:Migraine Disorders; D010148:Pain, Intractable; D010820:Physicians; D012720:Severity of Illness Index | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology | 2,013 | |
Enhanced support for shared decision making reduced costs of care for patients with preference-sensitive conditions. | Shared decision making is an approach to care that seeks to fully inform patients about the risks and benefits of available treatments and engage them as participants in decisions about the treatments. Although recent federal and state policies pursue the expanded use of shared decision making as a way to improve care ... | 10.1377/hlthaff.2011.0941 | 23,381,521 | D003363:Cost Control; D003657:Decision Making; D003695:Delivery of Health Care; D005260:Female; D017048:Health Care Costs; D006801:Humans; D008297:Male; D008875:Middle Aged; D010358:Patient Participation; D057240:Patient Preference; D011787:Quality of Health Care | Health affairs (Project Hope) | 2,013 | |
Upregulation of chemokine receptor CCR10 is essential for glioma proliferation, invasion and patient survival. | Human gliomas are characterized by their invasion of normal brain structures irrespective of their grade of malignancy. Tumor cell invasion share many similarities with leukocyte trafficking, which is critically regulated by chemokines and their receptors. Here we report that the chemokine receptor CCR10 is highly expr... | 10.18632/oncotarget.2134 | 25,149,529 | D000818:Animals; D001932:Brain Neoplasms; D049109:Cell Proliferation; D005909:Glioblastoma; D064593:Heterografts; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D051057:Proto-Oncogene Proteins c-akt; D054447:Receptors, CCR10; D016019:Survival Analysis; D014162:Transfection; D015854:Up-Re... | Oncotarget | 2,014 | C515706:CCR10 protein, human; D054447:Receptors, CCR10; D051057:Proto-Oncogene Proteins c-akt |
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