title large_stringlengths 0 979 | abstract large_stringlengths 1 94.7k | doi large_stringlengths 0 71 | pmid int64 21 38.1M | mesh_terms large_stringlengths 0 1.47k | journal large_stringlengths 1 239 | pubdate int16 1.97k 2.02k | chemical_list large_stringlengths 0 1.47k |
|---|---|---|---|---|---|---|---|
The neural development of prosocial behavior from childhood to adolescence. | The transition from childhood to adolescence is marked by increasingly sophisticated social cognitive abilities that are paralleled by significant functional maturation of the brain. However, the role of social and neurobiological development in facilitating age differences in prosocial behavior remains unclear. Using ... | 10.1093/scan/nsy117 | 30,608,610 | D000293:Adolescent; D001921:Brain; D001931:Brain Mapping; D002648:Child; D003430:Cross-Sectional Studies; D003657:Decision Making; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010379:Peer Group; D017397:Prefrontal Cortex; D012919:Social Behavior; D013702:Temporal Lobe | Social cognitive and affective neuroscience | 2,019 | |
Inhibitory refinement of spatial frequency selectivity in single cells of the cat striate cortex. | Single cells in the cat striate cortex are more selective for the spatial frequency of sinewave grating stimuli than are cells of the retina or lateral geniculate nucleus. We have explored the possibility that this enhancement of selectivity results from spatial-frequency-selective inhibition. Stimulation with two supe... | 10.1016/0042-6989(91)90201-f | 1,858,324 | D000222:Adaptation, Physiological; D000818:Animals; D002415:Cats; D009433:Neural Inhibition; D009474:Neurons; D014793:Visual Cortex | Vision research | 1,991 | |
Reproductive Performance Following Transcervical Insemination with Frozen Thawed Semen in Ewes Submitted to Surgical Incision of Cervical Folds (SICF): Comparison with Laparoscopic Artificial Insemination. | Transcervical artificial insemination (AI) after the surgical incision of cervical folds (SICF) could represent a valid alternative to laparoscopic AI when frozen thawed semen is used. The aim of this experiment was to compare pregnancy (PR) and lambing rates (LR) of ewes submitted either to transcervical AI after SICF... | 10.3390/ani10010108 | 31,936,444 | Animals : an open access journal from MDPI | 2,020 | ||
Minimally invasive radionuclide-guided parathyroidectomy using 99mTc-sestamibi in patients with primary hyperparathyroidism: a single-institution experience. | OBJECTIVE
To evaluate the efficacy and usefulness of (99m)Tc-sestamibi scintigraphy and gamma probe localization of parathyroid glands in patients with primary hyperparathyroidism and establish radio-guided minimally invasive parathyroidectomy at Hussain Makki Al Jumma Center for Specialized Surgery, Kuwait.
SUBJECTS... | 10.1159/000226291 | 19,648,760 | D000236:Adenoma; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D049950:Hyperparathyroidism, Primary; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms; D016105:Parathyroidectomy; D015641:Radiography, Interventional; D011877:Radionuclide Imaging; D017256:Technetium Tc 99m Sestamibi | Medical principles and practice : international journal of the Kuwait University, Health Science Centre | 2,009 | D017256:Technetium Tc 99m Sestamibi |
Soya protein stimulates bile acid excretion by the liver and intestine through direct and indirect pathways influenced by the presence of dietary cholesterol. | Several studies using different animal models have demonstrated that the consumption of soya protein (SP) reduces serum cholesterol concentrations by increasing the excretion of bile acids (BA). However, the mechanism by which SP enhances BA excretion is not fully understood. Therefore, the aim of the present study was... | 10.1017/S0007114514000361 | 24,666,631 | D000071018:ATP Binding Cassette Transporter, Subfamily G, Member 5; D000071019:ATP Binding Cassette Transporter, Subfamily G, Member 8; D018528:ATP-Binding Cassette Transporters; D000818:Animals; D000924:Anticholesteremic Agents; D001647:Bile Acids and Salts; D002756:Cholagogues and Choleretics; D002791:Cholesterol, Di... | The British journal of nutrition | 2,014 | D000071018:ATP Binding Cassette Transporter, Subfamily G, Member 5; D000071019:ATP Binding Cassette Transporter, Subfamily G, Member 8; D018528:ATP-Binding Cassette Transporters; C480692:Abcg5 protein, rat; C480693:Abcg8 protein, rat; D000924:Anticholesteremic Agents; D001647:Bile Acids and Salts; D002756:Cholagogues a... |
Endoscopic ultrasound and EUS-guided FNA in the diagnosis of rectal endometriosis. | Endometriosis is characterised by the presence of endometrial glands and stroma outside the uterus. The GI tract is the most common site for extra-pelvic endometriosis, in particular the rectum and sigmoid colon. Using endoscopic ultrasound (EUS), which combines endoscopy with real-time ultrasonography, the wall of the... | 19,902,654 | D000328:Adult; D044963:Biopsy, Fine-Needle; D004715:Endometriosis; D019160:Endosonography; D005260:Female; D006801:Humans; D012002:Rectal Diseases | Irish medical journal | 2,009 | ||
Parkinson disease. Nonmotor symptoms in Parkinson disease: the PRIAMO study. | Nonmotor symptoms are assuming an increasingly important place in the constellation of clinical traits that characterize Parkinson disease. A multicenter survey of patients with Parkinson disease highlights the prevalence of these symptoms. The findings indicate that further research into the pathophysiology and treatm... | 10.1038/nrneurol.2009.156 | 19,794,513 | D006801:Humans; D015337:Multicenter Studies as Topic; D010300:Parkinson Disease; D011788:Quality of Life | Nature reviews. Neurology | 2,009 | |
Evaluation and surgical management of isolated sphenoid sinus disease. | OBJECTIVES
To evaluate the pathologic conditions, preoperative evaluation, treatment, and clinical outcomes associated with sphenoid sinus disease.
DESIGN
Retrospective study.
SETTING
Tertiary university-based referral center.
PATIENTS
All patients with isolated sphenoid sinus disease managed surgically or in whi... | 10.1001/archotol.128.12.1413 | 12,479,731 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010254:Paranasal Sinus Diseases; D010255:Paranasal Sinus Neoplasms; D012189:Retrospective Studies; D013101:Sphenoid Sinus; D015524:Sphenoid Sinusitis; D014057:Tomography, X-Ray... | Archives of otolaryngology--head & neck surgery | 2,002 | |
The potential effect of proteasome inhibitor PS-341 on severe acute pancreatitis detected by positron emission tomography in ICR mice. | INTRODUCTION
Severe acute pancreatitis is a life threatening disease with a high rate of mortality, and its treatments are still controversial. The purpose of this study is to investigate the potential effects of proteasome inhibitor PS-341 on severe acute pancreatitis induced by cerulein and lipopolysaccharide in mice... | 10.1016/j.jss.2009.06.011 | 20,006,347 | D000681:Amylases; D000818:Animals; D017209:Apoptosis; D001897:Boronic Acids; D000069286:Bortezomib; D002097:C-Reactive Protein; D002108:Ceruletide; D005260:Female; D007249:Inflammation; D053583:Interleukin-1beta; D007770:L-Lactate Dehydrogenase; D051379:Mice; D008813:Mice, Inbred ICR; D010195:Pancreatitis; D049268:Posi... | The Journal of surgical research | 2,010 | D001897:Boronic Acids; D053583:Interleukin-1beta; D011480:Protease Inhibitors; D011719:Pyrazines; D000069286:Bortezomib; D002108:Ceruletide; D002097:C-Reactive Protein; D007770:L-Lactate Dehydrogenase; D000681:Amylases |
Peripheral Immune Profile and Neutrophil-to-Lymphocyte Ratio in Parkinson's Disease. | BACKGROUND
The neutrophil-to-lymphocyte ratio (NLR) in peripheral blood is a well-established inflammatory marker, but its role in Parkinson's disease (PD) remains unclear.
OBJECTIVES
To determine whether a different peripheral immune profile and NLR were present in PD patients.
METHODS
We conducted a case-control ... | 10.1002/mds.28685 | 34,101,890 | D015415:Biomarkers; D016022:Case-Control Studies; D006801:Humans; D008214:Lymphocytes; D009504:Neutrophils; D010300:Parkinson Disease | Movement disorders : official journal of the Movement Disorder Society | 2,021 | D015415:Biomarkers |
Raynaud's phenomenon in chain saw users. Hot and cold finger systolic pressures and nailfold capillary findings. | To gain insight into the physiopathology of Raynaud's phenomenon of occupational origin, finger systolic pressures under heat and cold, and results of nailfold capillary microscopy, were examined in 29 lumberjacks with Raynaud's phenomenon vibration syndrome (pathological group) and 24 lumberjacks without it (non-patho... | 10.1093/oxfordjournals.eurheartj.a062296 | 3,609,037 | D001794:Blood Pressure; D003080:Cold Temperature; D005385:Fingers; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008833:Microcirculation; D009262:Nails; D009784:Occupational Diseases; D011928:Raynaud Disease; D014732:Vibration | European heart journal | 1,987 | |
Late hemodynamic effects of the preserved papillary muscles during mitral valve replacement. | BACKGROUND
The late hemodynamic effects of preserving the papillary muscles during mitral valve replacement have not been evaluated.
METHODS AND RESULTS
Sixteen patients who had chronic mitral regurgitation due to myxomatous degeneration were randomized to preservation (Pres group, n = 8) or no preservation (No Pres ... | 7,955,250 | D002815:Chordae Tendineae; D005260:Female; D005500:Follow-Up Studies; D015637:Gated Blood-Pool Imaging; D006350:Heart Valve Prosthesis; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency; D010210:Papillary Muscles; D011446:Prospective Studie... | Circulation | 1,994 | ||
Effects of hypoxia on the luminance threshold for target detection. | A technique is described--for determining luminance thresholds for detection of realistic target objects--which is suitable for use in simulators and environmental chambers. Data obtained by this technique during a 10-d exposure to high altitude indicate impairments of target detection in direct relation to target view... | 6,838,446 | D000293:Adolescent; D000328:Adult; D000531:Altitude; D006801:Humans; D000860:Hypoxia; D008027:Light; D008297:Male; D013997:Time Factors; D014796:Visual Perception | Aviation, space, and environmental medicine | 1,983 | ||
Transplant tourism to China: the impact on domestic patient-care decisions. | UNLABELLED
Organ procurement in China has been criticized because of its reliance on executed prisoners as donors. We aimed to assess the influence of perceptions about organ procurement practices in China on domestic patient-care decisions.
METHODS
An anonymous internet administered case-based questionnaire was used... | 10.1111/j.1399-0012.2008.00949.x | 19,191,815 | D001291:Attitude of Health Personnel; D002681:China; D002983:Clinical Competence; D003657:Decision Making; D004992:Ethics, Medical; D005260:Female; D006297:Health Services Accessibility; D006801:Humans; D008103:Liver Cirrhosis; D016031:Liver Transplantation; D008297:Male; D057193:Medical Tourism; D008875:Middle Aged; D... | Clinical transplantation | 2,009 | |
Editorial: Advances on targeted nanomedicines for atherosclerosis. | The importance of nanomedicines for atherosclerosis. | 10.3389/fphar.2022.1053938 | 36,313,335 | Frontiers in pharmacology | 2,022 | ||
First Report of Soft Rot of Pitahaya Fruit Caused by Gilbertella persicaria in Mexico. | Pitahaya (Hylocereus spp.), also called dragon fruit, is a cultivated cactus that is native to Mexico as well as Central and South America. In September 2021, soft rot of fruit of H. ocamponis, H. undatus, and H. costaricensis was observed in a commercial orchard located in La Cruz de Elota, Sinaloa, Mexico. The diseas... | 10.1094/PDIS-01-22-0142-PDN | 35,581,917 | Plant disease | 2,022 | ||
Reducing Vocal Fatigue With Bone Conduction Devices: Comparing Forbrain and Sidetone Amplification. | PURPOSE
Altered auditory feedback research aims to identify methods to strengthen speakers' awareness of their own voicing behaviors, diminish their perception of vocal fatigue, and improve their voice production. This study aims to compare the effects of two bone conduction devices that provide altered auditory feedba... | 10.1044/2023_JSLHR-23-00409 | 37,844,616 | D006801:Humans; D002675:Child, Preschool; D055815:Young Adult; D000328:Adult; D001844:Bone Conduction; D014831:Voice; D014832:Voice Disorders; D013061:Speech Acoustics; D000162:Acoustics | Journal of speech, language, and hearing research : JSLHR | 2,023 | |
Molecular fine-needle aspiration biopsy diagnosis of thyroid nodules by tumor specific mutations and gene expression patterns. | Fine-needle aspiration biopsy (FNAB) is currently the most sensitive and specific tool for the presurgical differential diagnosis of thyroid malignancy, but has also substantial limitations. While approximately 75% of FNAB reveal benign lesions and 5% already cytologically prove malignancy, up to 20% of FNAB show folli... | 10.1016/j.mce.2010.01.010 | 20,083,161 | D018263:Adenocarcinoma, Follicular; D014408:Biomarkers, Tumor; D044963:Biopsy, Fine-Needle; D002291:Carcinoma, Papillary; D003937:Diagnosis, Differential; D020869:Gene Expression Profiling; D006801:Humans; D009154:Mutation; D013964:Thyroid Neoplasms; D016606:Thyroid Nodule | Molecular and cellular endocrinology | 2,010 | D014408:Biomarkers, Tumor |
Use of selenium-silymarin mix reduces lower urinary tract symptoms and prostate specific antigen in men. | The aim of this double-blind, placebo controlled clinical trial was to assess the effects of a combination of selenium and silymarin in men with lower urinary tract symptoms, benign prostatic hyperplasia and a prostate specific antigen (PSA) ≤2.5ng/ml. The volunteers were randomized to two groups: the first one (n=26) ... | 24,012,146 | D000368:Aged; D004311:Double-Blind Method; D004338:Drug Combinations; D006801:Humans; D059411:Lower Urinary Tract Symptoms; D008297:Male; D008875:Middle Aged; D020944:Silybum marianum; D008517:Phytotherapy; D010936:Plant Extracts; D017430:Prostate-Specific Antigen; D011470:Prostatic Hyperplasia; D012643:Selenium; D0128... | Phytomedicine : international journal of phytotherapy and phytopharmacology | 2,013 | D004338:Drug Combinations; D010936:Plant Extracts; D012838:Silymarin; D014131:Trace Elements; D013739:Testosterone; D017430:Prostate-Specific Antigen; D012643:Selenium | |
Label-free high-throughput detection and content sensing of individual droplets in microfluidic systems. | This study reports a microwave-microfluidics integrated approach capable of performing droplet detection at high-throughput as well as content sensing of individual droplets without chemical or physical intrusion. The sensing system consists of a custom microwave circuitry and a spiral-shaped microwave resonator that i... | 10.1039/c5lc00314h | 26,351,007 | D000818:Animals; D004553:Electric Conductivity; D056656:Lab-On-A-Chip Devices; D008872:Microwaves; D018511:Systems Integration | Lab on a chip | 2,015 | |
An Elderly Care System Based on Multiple Information Fusion. | With the development of social economy in the 21st century, and the rising of medical level, the aging of population have become a global trend. However lots of elderly people are in "empty nest" state. In order to solve the problem of high risk of daily life in this group, this paper proposed a method to integrate the... | 10.1155/2018/4098237 | 29,599,947 | D002681:China; D003195:Computer Communication Networks; D004867:Equipment Design; D006299:Health Services for the Aged; D006699:Home Care Services; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018670:Monitoring, Ambulatory; D014741:Video Recording | Journal of healthcare engineering | 2,018 | |
Alkaline Technosol contaminated by former mining activity and its culturable autochthonous microbiota. | Technosols or technogenic substrates contaminated by potentially toxic elements as a result of iron mining causes not only contamination of the surrounding ecosystem but may also lead to changes of the extent, abundance, structure and activity of soil microbial community. Microbial biomass were significantly inhibited ... | 10.1016/j.chemosphere.2016.11.131 | 28,006,667 | D001151:Arsenic; D001419:Bacteria; D018533:Biomass; D003300:Copper; D005658:Fungi; D008345:Manganese; D064307:Microbiota; D008906:Mining; D012988:Soil Microbiology; D012989:Soil Pollutants | Chemosphere | 2,017 | D012989:Soil Pollutants; D008345:Manganese; D003300:Copper; D001151:Arsenic |
A new method for the estimation of minimum adult frog density from a large-scale audial survey. | Audial surveys of anuran amphibians (frogs, toads and similar) are cost-effective and allow for the coverage of large areas, but they are usually regarded as unsuitable for population size estimations due to imperfect detection. Our study demonstrated a method for obtaining minimum adult population size estimates from ... | 10.1038/s41598-020-65560-6 | 32,451,461 | D000818:Animals; D001001:Anura; D001947:Breeding; D008297:Male; D011156:Population Density; D012621:Seasons; D014828:Vocalization, Animal | Scientific reports | 2,020 | |
Immunizations: how do your patients score? | Immunization is one of the most powerful preventive measures available. Nurse practitioners can use the social determinants of health framework to analyze structural-level barriers and practice-level clinical microsystems to improve immunization rates. | 10.1097/01.NPR.0000421430.62425.e5 | 23,076,236 | D000293:Adolescent; D002648:Child; D005260:Female; D005544:Forecasting; D006297:Health Services Accessibility; D040361:Healthy People Programs; D006801:Humans; D007114:Immunization; D008297:Male; D017146:Models, Organizational; D009722:Nurse Practitioners; D015403:Nursing Evaluation Research; D010353:Patient Education ... | The Nurse practitioner | 2,012 | |
Antioxidants Supplementation Reduces Ceramide Synthesis Improving the Cardiac Insulin Transduction Pathway in a Rodent Model of Obesity. | Obesity-related disruption in lipid metabolism contributes to cardiovascular dysfunction. Despite numerous studies on lipid metabolism in the left ventricle, there is no data describing the influence of n-acetylcysteine (NAC) and α-lipoic acid (ALA), as glutathione precursors, on sphingolipid metabolism, and insulin re... | 10.3390/nu13103413 | 34,684,414 | D000821:Animal Feed; D000818:Animals; D000975:Antioxidants; D015415:Biomarkers; D001835:Body Weight; D002518:Ceramides; D059305:Diet, High-Fat; D019587:Dietary Supplements; D005947:Glucose; D007328:Insulin; D007333:Insulin Resistance; D008297:Male; D053858:Metabolic Networks and Pathways; D023421:Models, Animal; D00920... | Nutrients | 2,021 | D000975:Antioxidants; D015415:Biomarkers; D002518:Ceramides; D007328:Insulin; D013107:Sphingolipids; D005947:Glucose |
Hemorrhagic shock with paradoxical bradycardia. | Two hundred and seventy-three acute hemorrhagic shocks were treated in 1984 in a pre-hospital emergency care unit. Twenty patients (7%) had a paradoxical bradycardia: they were conscious, 9 of them had an undetectable systolic arterial pressure with the sphygmomanometric method but the femoral pulse was still present. ... | 10.1007/BF00254705 | 3,584,650 | D000293:Adolescent; D000328:Adult; D001285:Atropine; D001919:Bradycardia; D003131:Combined Modality Therapy; D003422:Critical Care; D005260:Female; D005440:Fluid Therapy; D006339:Heart Rate; D006801:Humans; D008297:Male; D011312:Pressure; D012771:Shock, Hemorrhagic | Intensive care medicine | 1,987 | D001285:Atropine |
Results of Destandau microendoscopic lumbar discectomy. | BACKGROUND AND PURPOSE
Endoscopic methods are increasingly used in spine surgery, including the operative treatment of lumbar disc herniation. In this study we present a clinical series of 45 patients with lumbar disc prolapse who were operated on endoscopically with ENDOSPINE instrumentation (Karl STORZ GmbH and Co. K... | 18,512,166 | D000293:Adolescent; D000328:Adult; D019299:Decompression, Surgical; D017586:Diskectomy; D004724:Endoscopy; D005260:Female; D006801:Humans; D007405:Intervertebral Disc Displacement; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D011044:Poland; D015641:Radiog... | Neurologia i neurochirurgia polska | 2,008 | ||
Quantitative review of ruminal and total tract digestion of mixed diet organic matter and carbohydrates. | The mean response and main factors of variation (level of concentrate, nature of carbohydrate in the concentrate and level of intake) for organic matter, cell wall material, starch digestion and microbial synthesis in the gastrointestinal tract of ruminants were quantitatively reviewed using a data base involving 157 p... | 10.1051/rnd:19970205 | 9,178,358 | D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002417:Cattle; D002473:Cell Wall; D004032:Diet; D004040:Dietary Carbohydrates; D004063:Digestion; D012417:Rumen; D012756:Sheep | Reproduction, nutrition, development | 1,997 | D004040:Dietary Carbohydrates |
Exploring the Relationship Between Domestic Violence Perpetration and Suicidal Behavior in Male Prisoners. | This study is the first to explore the relationship between domestic violence perpetration and suicidal behavior in prisoners in England and Wales. The nature of this relationship is unclear, however, understanding and reducing suicide in prisons is a critical issue for frontline staff and policy makers. Eight particip... | 10.1080/13811118.2021.1939207 | 34,162,317 | D008297:Male; D006801:Humans; D059020:Suicidal Ideation; D011329:Prisoners; D011330:Prisons; D013406:Suicide, Attempted; D017579:Domestic Violence | Archives of suicide research : official journal of the International Academy for Suicide Research | 2,022 | |
Image feature analysis and computer-aided diagnosis in digital radiography: automated analysis of sizes of heart and lung in chest images. | We are developing an automated method for determining a number of parameters related to the size and shape of the heart and of the lungs in chest radiographs. In order to obtain standard patterns of the cardiac shadow as "gold standards," four radiologists traced their best estimates of the entire contour of the heart,... | 10.1118/1.596513 | 2,143,554 | D006332:Cardiomegaly; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008168:Lung; D011856:Radiographic Image Enhancement; D011857:Radiographic Image Interpretation, Computer-Assisted; D013902:Radiography, Thoracic | Medical physics | 1,990 | |
Social balance as a satisfiability problem of computer science. | Reduction of frustration was the driving force in an approach to social balance as it was recently considered by Antal [T. Antal, P. L. Krapivsky, and S. Redner, Phys. Rev. E 72, 036121 (2005)]. We generalize their triad dynamics to k-cycle dynamics for arbitrary integer k. We derive the phase structure, determine the ... | 10.1103/PhysRevE.75.026106 | 17,358,393 | Physical review. E, Statistical, nonlinear, and soft matter physics | 2,007 | ||
Endovascular treatment for wide-necked intracranial aneurysms with the Enterprise stent. | BACKGROUND
The development of self-expanding stents dedicated to intracranial use has significantly widened the applicability of endovascular therapy to many intracranial aneurysms
OBJECTIVE
To report the angiographic and clinical outcomes of wide-necked intracranial aneurysms treated using the Enterprise stent.
MA... | 10.4103/0028-3886.84335 | 21,891,931 | D000328:Adult; D017023:Coronary Angiography; D004621:Embolization, Therapeutic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D002532:Intracranial Aneurysm; D008297:Male; D008875:Middle Aged; D009333:Neck; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment ... | Neurology India | 2,011 | |
Lofepramine in the elderly. | Depression prevails in 12-13% of the elderly, of whom a 5th suffer major depressive illness. First admission-rates to psychiatric beds in England increase with aging until the 80s, when they fall off in women but continue to rise in men. Physical illness is a considerable contributor to depression in old age, and conse... | 3,063,744 | D000275:Adjustment Disorders; D000368:Aged; D003866:Depressive Disorder; D003984:Dibenzazepines; D006801:Humans; D008127:Lofepramine | International clinical psychopharmacology | 1,988 | D003984:Dibenzazepines; D008127:Lofepramine | |
The stomata of the fern Adiantum capillus-veneris do not respond to CO2 in the dark and open by photosynthesis in guard cells. | The stomata of the fern Adiantum capillus-veneris lack a blue light-specific opening response but open in response to red light. We investigated this light response of Adiantum stomata and found that the light wavelength dependence of stomatal opening matched that of photosynthesis. The simultaneous application of red ... | 10.1104/pp.108.118950 | 18,467,462 | D035681:Adiantum; D002245:Carbon Dioxide; D003624:Darkness; D004237:Diuron; D004579:Electron Transport; D010788:Photosynthesis; D011188:Potassium | Plant physiology | 2,008 | D002245:Carbon Dioxide; D004237:Diuron; D011188:Potassium |
Temporal stability of multiple response systems to 7.5% carbon dioxide challenge. | Self-reported anxiety, and potentially physiological response, to maintained inhalation of carbon dioxide (CO2) enriched air shows promise as a putative marker of panic reactivity and vulnerability. Temporal stability of response systems during low-dose, steady-state CO2 breathing challenge is lacking. Outcomes on mult... | 10.1016/j.biopsycho.2017.01.014 | 28,163,046 | D000223:Adaptation, Psychological; D000280:Administration, Inhalation; D000328:Adult; D001007:Anxiety; D002245:Carbon Dioxide; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D016584:Panic Disorder; D012119:Respiration; D056152:Respiratory Rate; D055815:Young Adult | Biological psychology | 2,017 | D002245:Carbon Dioxide |
Functional outcome following extensor synovectomy and excision of the distal ulna in patients with rheumatoid arthritis. | We prospectively measured hand and wrist function in rheumatoid patients undergoing excision of the distal ulna. Range of motion, visual analogue pain scores and grip strength were measured in 22 wrists, and the Jebsen hand function test was administered to seven patients, preoperatively and at 3 and 12 months. At 1 ye... | 10.1016/s0266-7681(03)00099-8 | 14,599,824 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid; D005260:Female; D005500:Follow-Up Studies; D018737:Hand Strength; D006801:Humans; D008297:Male; D008875:Middle Aged; D009048:Motor Skills; D010147:Pain Measurement; D011183:Postoperative Complications; D011446:Prospective Studies; D0... | Journal of hand surgery (Edinburgh, Scotland) | 2,003 | |
Evaluation of MR thermometry with proton resonance frequency method at 7T. | Quantitative and non-invasive temperature mapping using magnetic resonance imaging (MRI) provides a unique way to measure temperature evolution inside biological tissues. The method is widely used in thermal ablation procedures with magnetic fields at or below 3T. In this paper, the sensitivity of the MRI thermometry a... | 10.21037/qims.2017.03.05 | 28,516,051 | Quantitative imaging in medicine and surgery | 2,017 | ||
Toward improved prediction of risk for atopy and asthma among preschoolers: a prospective cohort study. | BACKGROUND
Atopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children. However, effective methods for assessing the level of risk in individual children are lacking.
OBJECTIVE
We sought to identify clinical and laborator... | 10.1016/j.jaci.2009.12.018 | 20,226,300 | D000818:Animals; D001249:Asthma; D015415:Biomarkers; D002675:Child, Preschool; D015331:Cohort Studies; D006801:Humans; D006969:Hypersensitivity, Immediate; D007073:Immunoglobulin E; D007223:Infant; D007231:Infant, Newborn; D008137:Longitudinal Studies; D039981:Pyroglyphidae; D012135:Respiratory Sounds; D012141:Respirat... | The Journal of allergy and clinical immunology | 2,010 | D015415:Biomarkers; D007073:Immunoglobulin E |
Virulence-associated genes and antibiotic susceptibility among vaginal and rectal Escherichia coli isolates from healthy pregnant women in Poland. | Vaginal and/or rectal Escherichia coli colonization of pregnant women is sometimes associated with neonatal infections. Despite the relevance of these strains, they have been rarely described before. Thus, the aim of this study was to compare vaginal (VEC) and rectal E. coli (REC) isolates in respect of antimicrobial s... | 10.1007/s12223-018-0598-z | 29,644,511 | D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli; D004927:Escherichia coli Infections; D005260:Female; D005798:Genes, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D011044:Poland; D011247:Pregnancy; D011251:Pregnancy Complications, Inf... | Folia microbiologica | 2,018 | D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D037521:Virulence Factors |
Pneumatosis cystoides intestinalis revealed after a hand-to-hand aggression: A case report. | INTRODUCTION
Pneumatosis cystoides intestinalis (PCI) is a condition defined by the presence of multiple gas-filled cysts within the intestinal wall. We demonstrated a case of PCI presenting as pneumoperitoneum following a hand-to-hand aggression. Consent was obtained from the patient for publication of this paper.
P... | 10.1016/j.ijscr.2019.07.071 | 31,493,662 | International journal of surgery case reports | 2,019 | ||
Comment on "Temporal and spatial variation in harbor seal (Phoca vitulina L.) roar calls from southern Scandinavia" [J. Acoust. Soc. Am. 141, 1824-1834 (2017)]. | In their recent article, Sabinsky and colleagues investigated heterogeneity in harbor seals' vocalizations. The authors found seasonal and geographical variation in acoustic parameters, warning readers that recording conditions might account for some of their results. This paper expands on the temporal aspect of the en... | 10.1121/1.5021770 | 29,390,742 | The Journal of the Acoustical Society of America | 2,018 | ||
Endogenous ACh tonically stimulates ANP secretion in rat atria. | Exogenous acetylcholine (ACh) is known to stimulate atrial natriuretic peptide (ANP) secretion concomitantly with a decrease in atrial pulse pressure. However, the role of intrinsic ACh in the regulation of ANP secretion remains unknown. Recently, it was shown that nonneuronal and neuronal ACh is present in the cardiac... | 10.1152/ajpheart.00469.2013 | 23,913,708 | D000109:Acetylcholine; D000818:Animals; D016275:Atrial Function; D009320:Atrial Natriuretic Factor; D002800:Cholinesterase Inhibitors; D004305:Dose-Response Relationship, Drug; D006325:Heart Atria; D006439:Hemodynamics; D008297:Male; D018727:Muscarinic Antagonists; D032383:Myocytes, Cardiac; D009419:Nerve Tissue Protei... | American journal of physiology. Heart and circulatory physiology | 2,013 | D002800:Cholinesterase Inhibitors; D018727:Muscarinic Antagonists; D009419:Nerve Tissue Proteins; D050480:Plasma Membrane Neurotransmitter Transport Proteins; D026902:Potassium Channel Blockers; D015221:Potassium Channels; C075746:Slc6a8 protein, rat; D009320:Atrial Natriuretic Factor; D000109:Acetylcholine |
Propofol improves recovery of the isolated working hypertrophic heart from ischaemia-reperfusion. | The general anaesthetic propofol shows promise in protecting normal hearts against various cardiac insults, but little is known about its cardioprotective potential in hypertrophic hearts. This study tested the hypothesis that propofol at a clinically relevant dose would enhance functional recovery in hypertrophic hear... | 10.1007/s00424-012-1152-5 | 23,001,119 | D000818:Animals; D002302:Cardiac Output; D006332:Cardiomegaly; D066298:In Vitro Techniques; D015425:Myocardial Reperfusion; D032383:Myocytes, Cardiac; D009243:NAD; D015742:Propofol; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D013318:Stroke Volume | Pflugers Archiv : European journal of physiology | 2,012 | D009243:NAD; D015742:Propofol |
Event-related potentials elicited by errors during the stop-signal task. II: human effector-specific error responses. | Although previous research with human and nonhuman primates has examined the neural correlates of performance monitoring, discrepancies in methodology have limited our ability to make cross-species generalizations. One major obstacle arises from the use of different behavioral responses and tasks across different prima... | 10.1152/jn.00803.2011 | 22,357,790 | D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D002540:Cerebral Cortex; D004569:Electroencephalography; D005071:Evoked Potentials; D056344:Executive Function; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D011597:Psychomotor Performance; D011930:Reaction Time; D012438:Saccad... | Journal of neurophysiology | 2,012 | |
Isokinetic, isometric and isotonic strength relationships. | Relationships among isokinetic, isometric and isotonic strength measurements in knee and elbow extension and flexion were examined in 16 young, healthy men. Isokinetic and isometric torque measurements were obtained from modified Cybex II apparatus. Isokinetic torque values were obtained at velocities of 36 degrees/sec... | 6,824,423 | D000328:Adult; D001696:Biomechanical Phenomena; D006801:Humans; D007537:Isometric Contraction; D007596:Joints; D008297:Male; D008722:Methods; D009119:Muscle Contraction; D009132:Muscles; D005082:Physical Exertion | Archives of physical medicine and rehabilitation | 1,983 | ||
Serum lipids and lipoproteins in newly diagnosed non-insulin-dependent (type II) diabetic patients, with special reference to factors influencing HDL-cholesterol and triglyceride levels. | Serum and lipoprotein lipids were examined in 133 newly diagnosed (type II) diabetic patients (70 men, 63 women), aged 45-64 yr, and in 144 randomly selected nondiabetic control subjects of similar age (62 men, 82 women). The serum total cholesterol levels in diabetic and nondiabetic subjects were similar, but the HDL-... | 10.2337/diacare.9.1.17 | 3,081,307 | D000368:Aged; D016632:Apolipoprotein A-I; D016633:Apolipoprotein A-II; D001054:Apolipoproteins A; D001835:Body Weight; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D008055:Lipids; D008074:Lipoproteins; D008297:Male; D008875:Middle Aged; D014280:T... | Diabetes care | 1,986 | D016632:Apolipoprotein A-I; D016633:Apolipoprotein A-II; D001054:Apolipoproteins A; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D008074:Lipoproteins; D014280:Triglycerides |
The immunomodulatory activity of Staphylococcus aureus products derived from biofilm and planktonic cultures. | Biofilms are probably one of the most common structures formed by microorganisms in various environments. The higher resistance of such microbial communities to stress conditions, including antibiotics and host immune response, is recently extensively studied. However, the weak activity of phagocytic cells against micr... | 10.1007/s00005-013-0240-3 | 23,925,370 | D000818:Animals; D018441:Biofilms; D002478:Cells, Cultured; D003550:Cystic Fibrosis; D016207:Cytokines; D004352:Drug Resistance, Microbial; D006461:Hemolysis; D006801:Humans; D057131:Immune Evasion; D007113:Immunity, Innate; D017737:Macrophages, Peritoneal; D008666:Metalloendopeptidases; D051379:Mice; D008807:Mice, Inb... | Archivum immunologiae et therapiae experimentalis | 2,013 | D016207:Cytokines; D011135:Polysaccharides, Bacterial; D008666:Metalloendopeptidases; C022653:auR protein, Staphylococcus aureus |
Development of a dried blood spot HPLC-PDA method for the analysis of linezolid and ciprofloxacin in hospital-acquired pneumonia patients. | This study developed a high performance liquid chromatography (HPLC) method involving dried blood spotting (DBS) as a sampling method for the therapeutic drug monitoring of antimicrobial combination therapy with linezolid and ciprofloxacin. DBS for standards, quality control samples, and patient samples was excised and... | 10.1002/dta.2195 | 28,334,502 | D000900:Anti-Bacterial Agents; D002851:Chromatography, High Pressure Liquid; D002939:Ciprofloxacin; D003428:Cross Infection; D059788:Dried Blood Spot Testing; D016903:Drug Monitoring; D006801:Humans; D057230:Limit of Detection; D000069349:Linezolid; D011014:Pneumonia | Drug testing and analysis | 2,017 | D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D000069349:Linezolid |
Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors. | The synthesis of deflazacort (DFZ) and a preliminary evaluation of its microbial activity against the human pathogens Acinetobacter baumannii and Staphylococcus aureus is herein reported. While DFZ is inactive, one of its synthetic precursors showed a strong antibacterial activity against both Gram-negative and -positi... | 10.1039/c9ra03673c | 35,521,350 | RSC advances | 2,019 | ||
Carrier-envelope phase dependence of non-sequential double ionization in few-cycle pulses. | The influence of carrier-envelope phase (CEP) of a few-cycle laser pulse on non-sequential double ionization (NSDI) of an atom is investigated by applying the three-dimensional semi-classical re-scattering method. The asymmetric momentum distribution of the double-charged ion parallel to the laser polarization, which d... | 10.1364/oe.16.020562 | 19,065,194 | D003198:Computer Simulation; D005740:Gases; D007477:Ions; D007834:Lasers; D008027:Light; D008962:Models, Theoretical; D011789:Quantum Theory; D012542:Scattering, Radiation | Optics express | 2,008 | D005740:Gases; D007477:Ions |
MiR-873, as a suppressor in cervical cancer, inhibits cells proliferation, invasion and migration via negatively regulating ULBP2. | BACKGROUND
Cervical cancer (CC) remains a large burden in the developing countries. The tumor inhibitory role of miR-873 has been verified in a variety of cancers, however, whether miR-873 has a suppressive effect on CC remains unclear.
OBJECTIVE
The purpose of this study was to investigate the functional role of miR... | 10.1007/s13258-019-00905-8 | 31,902,110 | D002460:Cell Line; D002465:Cell Movement; D049109:Cell Proliferation; D005260:Female; D058851:GPI-Linked Proteins; D015972:Gene Expression Regulation, Neoplastic; D006367:HeLa Cells; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins; D035683:MicroRNAs; D002583:Uterine Cervical Neoplasms | Genes & genomics | 2,020 | D058851:GPI-Linked Proteins; D036341:Intercellular Signaling Peptides and Proteins; C000598459:MIRN873 microRNA, human; D035683:MicroRNAs; C423230:ULBP2 protein, human |
Micellization of Polystyrene-b-Polyglycidol in Dioxane and Water/Dioxane Solutions. | In this work, the self-assembly of a series of amphiphilic polystyrene-b-polyglycidol (PS-b-PGL) diblock copolymers in dioxane and dioxane/water mixtures is presented. The PS-b-PGL have an average degree of polymerization (DP) of PS block equal to 29 units and varied degrees of polymerization for the glycidol segments ... | 10.3390/polym12010200 | 31,941,035 | Polymers | 2,020 | ||
Epinephrine and dopamine beta-hydroxylase secretion from bovine adrenal. | The perfusate of the isolated, acetylcholine-stimulated bovine adrenal was studied for epinephrine (E) concentration and dopamine beta-hydroxylase (DBH) activity. Analysis of single stimuli showed that DBH disappeared from the perfusate with a t1/2 of 19.1-29.0 min. whereas E disappeared with a t1/2 of 0.78-1.0 min. St... | 10.1152/ajpendo.1978.234.6.E600 | 665,763 | D000109:Acetylcholine; D000311:Adrenal Glands; D000818:Animals; D002417:Cattle; D004299:Dopamine beta-Hydroxylase; D004837:Epinephrine; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D009638:Norepinephrine; D010477:Perfusion; D010643:Phenoxybenzamine; D010625:Phenylethanolamine N-Methyltransferase | The American journal of physiology | 1,978 | D010643:Phenoxybenzamine; D004299:Dopamine beta-Hydroxylase; D010625:Phenylethanolamine N-Methyltransferase; D000109:Acetylcholine; D009638:Norepinephrine; D004837:Epinephrine |
The retinol-retinoic acid metabolic pathway is impaired in the lumbar spine of a rat model of congenital kyphoscoliosis. | Although congenital scoliosis is defined as a genetic disease characterized by a congenital and abnormal curvature of the spinal vertebrae, our knowledge of the genetic underpinnings of the disease is insufficient. We herein show that the downregulation of the retinol-retinoic acid metabolism pathway is involved in the... | 10.1002/jcb.28762 | 31,056,772 | D000426:Alcohol Dehydrogenase; D000818:Animals; D055396:Bone Morphogenetic Protein 2; D007738:Kyphosis; D008159:Lumbar Vertebrae; D008161:Lumbosacral Region; D010012:Osteogenesis; D051381:Rats; D017208:Rats, Wistar; D050697:Retinal Dehydrogenase; D000072482:Retinoic Acid Receptor alpha; D012600:Scoliosis; D014212:Treti... | Journal of cellular biochemistry | 2,019 | C525720:Bmp2 protein, rat; D055396:Bone Morphogenetic Protein 2; C000607073:Rara protein, rat; D000072482:Retinoic Acid Receptor alpha; D014801:Vitamin A; D014212:Tretinoin; D000426:Alcohol Dehydrogenase; C521403:Aldh1a2 protein, rat; D050697:Retinal Dehydrogenase |
Inhibition by -amanitin of simian virus 40-specific ribonucleic acid synthesis in nuclei of infected monkey cells. | Conditions affecting the synthesis of simian virus 40-specific ribonucleic acid (RNA) in nuclei isolated from lytically infected cells were investigated. Deoxyribonucleic acid-RNA hybridization results show that an alpha-amanitin-sensitive RNA polymerase activity is responsible for transcription of simian virus 40 deox... | 10.1128/JVI.10.5.1086-1089.1972 | 4,344,254 | D000818:Animals; D002460:Cell Line; D002467:Cell Nucleus; D002478:Cells, Cultured; D004261:DNA Replication; D004279:DNA, Viral; D012321:DNA-Directed RNA Polymerases; D000882:Haplorhini; D007668:Kidney; D009183:Mycotoxins; D009693:Nucleic Acid Hybridization; D010455:Peptides; D012313:RNA; D012367:RNA, Viral; D013539:Sim... | Journal of virology | 1,972 | D004279:DNA, Viral; D009183:Mycotoxins; D010455:Peptides; D012367:RNA, Viral; D014500:Uracil Nucleotides; D014316:Tritium; D012313:RNA; D012321:DNA-Directed RNA Polymerases |
Development of a severity discrimination scale based on physical quality of life for patients with chronic pain. | BACKGROUND
Deterioration of quality of life in patients with chronic pain is difficult to treat. Chronic pain in patients with low quality of life may be "severe" and require multidisciplinary treatments. This study aimed to develop an objective severity discrimination scale based on quality of life measurements to ide... | 10.1016/j.jos.2020.10.005 | 33,183,936 | D059350:Chronic Pain; D006801:Humans; D010147:Pain Measurement; D011788:Quality of Life; D012680:Sensitivity and Specificity; D012893:Sleep Wake Disorders | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association | 2,021 | |
Population Genomics of Domesticated Cucurbita ficifolia Reveals a Recent Bottleneck and Low Gene Flow with Wild Relatives. | Cucurbita ficifolia is a squash grown from Mexico to Bolivia. Its ancestor is unknown, but it has limited compatibility with wild xerophytic Cucurbita from Mexico's highlands. We assembled the reference genome of C. ficifolia and assessed the genetic diversity and historical demography of the crop in Mexico with 2524 n... | 10.3390/plants12233989 | 38,068,624 | Plants (Basel, Switzerland) | 2,023 | ||
Technologies of care and the engineering imaginary: Two approaches to assistive device design for the Global South. | Assistive devices serve as vectors for the ideals, judgments, and goals that their society of origin has towards people with disabilities. For some Ugandan inventors and prosthetists, familiarity with sociocultural norms and consistent feedback allow them to design prosthetic limbs as technologies of care that specific... | 10.1111/maq.12818 | 37,824,820 | Medical anthropology quarterly | 2,023 | ||
Study of serum haptoglobin level and its relation to erythropoietic activity in Beta thalassemia children. | BACKGROUND
Serum haptoglobin (Hp) is a reliable marker for hemolysis regardless the inflammatory state.
OBJECTIVE
We investigated the possible relation between Hp depletion and hemolysis severity, hepatitis C virus (HCV) infection and iron load in β-thalassemia children.
METHODS
Twenty two β-thalassemia major (TM),... | 10.4084/MJHID.2015.019 | 25,745,546 | Mediterranean journal of hematology and infectious diseases | 2,015 | ||
Meeting the needs of patients with cancer--a GP guide to support services. | BACKGROUND
A diagnosis of cancer places huge psychological and physical demands on individuals. Early stage cancer patients will frequently experience depression and elevated levels of anxiety.
OBJECTIVE
This article summarises the available cancer services, categorised to address patient needs, and suggests suitable... | 15,887,941 | D001315:Australia; D005194:Family Practice; D006699:Home Care Services; D015277:Hotlines; D006801:Humans; D009369:Neoplasms; D010353:Patient Education as Topic; D012657:Self-Help Groups; D012944:Social Support | Australian family physician | 2,005 | ||
Approaches to passive mosquito surveillance in the EU. | The recent emergence in Europe of invasive mosquitoes and mosquito-borne disease associated with both invasive and native mosquito species has prompted intensified mosquito vector research in most European countries. Central to the efforts are mosquito monitoring and surveillance activities in order to assess the curre... | 10.1186/s13071-014-0604-5 | 25,567,671 | D063147:Animal Distribution; D000818:Animals; D009033:Culicidae; D016208:Databases, Factual; D005062:European Union; D007303:Insect Vectors; D058865:Introduced Species; D009032:Mosquito Control; D011157:Population Dynamics | Parasites & vectors | 2,015 | |
Development of Australian clinical practice outcome standards for graduates of critical care nurse education. | AIMS AND OBJECTIVES
To develop critical care nurse education practice standards.
BACKGROUND
Critical care specialist education for registered nurses in Australia is provided at graduate level. Considerable variation exists across courses with no framework to guide practice outcomes or evidence supporting the level of... | 10.1111/jocn.12631 | 24,814,614 | D000328:Adult; D001315:Australia; D002983:Clinical Competence; D064648:Critical Care Nursing; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009740:Nursing Staff; D057184:Practice Patterns, Nurses'; D011795:Surveys and Questionnaires | Journal of clinical nursing | 2,015 | |
Dissociation of thermogenic and trophic actions of norepinephrine in brown adipocytes of Richardson ground squirrels. | Richardson ground squirrels are hibernators with seasonal changes in the thermogenic capacity of brown adipose tissue (BAT). The objective of this work was to evaluate whether norepinephrine (NE) acts both as a thermogenic and a growth factor in BAT. Brown adipocytes were isolated by collagenase digestion of axillary B... | 10.1139/y95-203 | 8,748,938 | D002001:Adipose Tissue, Brown; D000818:Animals; D001833:Body Temperature Regulation; D002352:Carrier Proteins; D005260:Female; D006605:Hibernation; D007473:Ion Channels; D008297:Male; D008565:Membrane Proteins; D008715:Methionine; D024101:Mitochondrial Proteins; D009638:Norepinephrine; D010101:Oxygen Consumption; D0141... | Canadian journal of physiology and pharmacology | 1,995 | D002352:Carrier Proteins; D007473:Ion Channels; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D000071256:Uncoupling Protein 1; D008715:Methionine; D009638:Norepinephrine |
Intraperitoneal injection of microencapsulated Sertoli cells restores muscle morphology and performance in dystrophic mice. | Duchenne muscular dystrophy (DMD) is a genetic disease characterized by progressive muscle degeneration leading to impaired locomotion, respiratory failure and premature death. In DMD patients, inflammatory events secondary to dystrophin mutation play a major role in the progression of the pathology. Sertoli cells (SeC... | 10.1016/j.biomaterials.2015.10.029 | 26,523,508 | D000818:Animals; D000893:Anti-Inflammatory Agents; D002470:Cell Survival; D002908:Chronic Disease; D004339:Drug Compounding; D006706:Homeostasis; D007274:Injections, Intraperitoneal; D008297:Male; D018101:Mice, Inbred mdx; D009132:Muscles; D009137:Muscular Dystrophy, Animal; D020890:Neuregulin-1; D020127:Recovery of Fu... | Biomaterials | 2,016 | D000893:Anti-Inflammatory Agents; D020890:Neuregulin-1; D049411:Utrophin; C087230:heregulin beta1 |
The role of DNA methylation in setting up chromatin structure during development. | DNA methylation inhibits gene expression in animal cells, probably by affecting chromatin structure. Biochemical studies suggest that this process may be mediated by methyl-specific binding proteins that recruit enzymatic machinery capable of locally altering histone modification. To test whether DNA methylation actual... | 10.1038/ng1158 | 12,740,577 | D000107:Acetylation; D000818:Animals; D002843:Chromatin; D018899:CpG Islands; D019175:DNA Methylation; D018507:Gene Expression Regulation, Developmental; D005914:Globins; D006657:Histones; D006801:Humans; D008239:Lysine; D008745:Methylation; D051379:Mice; D008822:Mice, Transgenic; D008957:Models, Genetic; D014162:Trans... | Nature genetics | 2,003 | D002843:Chromatin; D006657:Histones; D005914:Globins; D008239:Lysine |
Baicalein inhibits cell growth and increases cisplatin sensitivity of A549 and H460 cells via miR-424-3p and targeting PTEN/PI3K/Akt pathway. | Lung cancer is the leading cause of death in individuals with malignant disease. Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer, and chemotherapy drugs such as cisplatin are the most widely used treatment for this disease. Baicalein is a purified flavonoid compound that has been reported to i... | 10.1111/jcmm.13556 | 29,392,841 | D017209:Apoptosis; D002465:Cell Movement; D049109:Cell Proliferation; D002945:Cisplatin; D019008:Drug Resistance, Neoplasm; D044950:Flavanones; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008175:Lung Neoplasms; D035683:MicroRNAs; D051058:Oncogene Protein v-akt; D051059:PTEN Phosphohydrolase; D01986... | Journal of cellular and molecular medicine | 2,018 | D044950:Flavanones; C554214:MIRN424 microrna, human; D035683:MicroRNAs; C006680:baicalein; D019869:Phosphatidylinositol 3-Kinases; D051058:Oncogene Protein v-akt; D051059:PTEN Phosphohydrolase; C494929:PTEN protein, human; D002945:Cisplatin |
Maximum O2 uptake, O2 debt and deficit, and muscle metabolites in Thoroughbred horses. | This study determined maximal O2 uptake (VO2max), maximal O2 deficit, and O2 debt in the Thoroughbred racehorse exercising on an inclined treadmill. In eight horses the O2 uptake (VO2) vs. speed relationship was linear until 10 m/s and VO2max values ranged from 131 to 153 ml.kg-1.min-1. Six of these horses then exercis... | 10.1152/jappl.1988.64.2.781 | 3,372,435 | D000818:Animals; D006736:Horses; D000860:Hypoxia; D008297:Male; D009132:Muscles; D010101:Oxygen Consumption; D005082:Physical Exertion | Journal of applied physiology (Bethesda, Md. : 1985) | 1,988 | |
[Value of brain sonography in newborns and children (author's transl)]. | Intracranial changes of newborns and young children can easily be discovered by modern sonography, especially as long as fontanelles are still open. Sonography of brain first should be done before computed tomography, encephalography and/or ventriculography are performed. Correspondence of most sonographic findings and... | 7,302,206 | D001139:Arnold-Chiari Malformation; D001921:Brain; D001925:Brain Damage, Chronic; D001927:Brain Diseases; D001929:Brain Edema; D002543:Cerebral Hemorrhage; D002675:Child, Preschool; D003616:Dandy-Walker Syndrome; D006801:Humans; D006849:Hydrocephalus; D007223:Infant; D007231:Infant, Newborn; D008581:Meningitis; D014057... | Der Radiologe | 1,981 | ||
Phospholipase A2 activity can protect renal tubules from oxygen deprivation injury. | During hypoxic or ischemic renal tubular injury, phospholipase A2 (PLA2) induces membrane deacylation, causing fatty acid accumulation and phospholipid breakdown. Because these changes can compromise cellular integrity, PLA2 activity has been widely proposed as a critical mediator of hypoxic renal tubular injury and, h... | 10.1073/pnas.90.17.8297 | 8,367,497 | D000227:Adenine Nucleotides; D000818:Animals; D002118:Calcium; D002417:Cattle; D002470:Cell Survival; D004533:Egtazic Acid; D004734:Energy Metabolism; D005227:Fatty Acids; D000860:Hypoxia; D066298:In Vitro Techniques; D007687:Kidney Tubules, Proximal; D007700:Kinetics; D007770:L-Lactate Dehydrogenase; D008297:Male; D01... | Proceedings of the National Academy of Sciences of the United States of America | 1,993 | D000227:Adenine Nucleotides; D005227:Fatty Acids; D004533:Egtazic Acid; D007770:L-Lactate Dehydrogenase; D010741:Phospholipases A; D054467:Phospholipases A2; D002118:Calcium |
Contrast dependence of contextual effects in primate visual cortex. | The responses of neurons in the visual cortex to stimuli presented within their receptive fields can be markedly modulated by stimuli presented in surrounding regions that do not themselves evoke responses. This modulation depends on the relative orientation and direction of motion of the centre and surround stimuli, a... | 10.1038/387073a0 | 9,139,823 | D000818:Animals; D015350:Contrast Sensitivity; D008251:Macaca; D009474:Neurons; D014793:Visual Cortex | Nature | 1,997 | |
Evaluation of the efficacy and safety of sobrerol granules in patients suffering from chronic rhinosinusitis. | In a double-blind, randomized, placebo-controlled clinical trial, the safety and efficacy of 900 mg/day sobrerol granules given for up to 10 days was assessed in 40 patients with chronic catarrhal rhinosinusitis. At the beginning of treatment a total of six patients had a fever, whereas body temperature was normal in a... | 10.1177/030006059001800602 | 2,292,326 | D000328:Adult; D002908:Chronic Disease; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012220:Rhinitis; D012852:Sinusitis; D013729:Terpenes | The Journal of international medical research | 1,990 | D013729:Terpenes; C003316:sobrerol |
Transition of nodular toxic goiter to autoimmune hyperthyroidism triggered by 131I therapy. | The use of 131I treatment in nodular toxic goiter is widely accepted. In this article, we describe transition of nodular toxic goiter into an autoimmune toxic goiter with development of thyrotropin receptor antibodies (TRAb) as a side effect of 131I treatment. In this retrospective study, 149 patients with nodular toxi... | 10.1089/thy.1999.9.477 | 10,365,679 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006044:Goiter, Nodular; D006111:Graves Disease; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D011878:Radiotherapy; D012189:Retrospective Studies; D013960:Thyroid Function Tests; D01396... | Thyroid : official journal of the American Thyroid Association | 1,999 | D007457:Iodine Radioisotopes |
Are the Persistent Postural-Perceptual Dizziness (PPPD) Patients More Anxious than the Patients with Other Dizziness? | BACKGROUND
The Behavioral Subcommittee of the Bárány Society Committee for Classification of Vestibular Disorders recently established the diagnostic criteria for a persistent postural-perceptive dizziness (PPPD).
OBJECTIVES
This study aims to determine how significant the degree of anxiety and depression of PPPD pat... | 10.24869/psyd.2022.71 | 35,467,613 | D001007:Anxiety; D004244:Dizziness; D006801:Humans; D014717:Vertigo; D015837:Vestibular Diseases | Psychiatria Danubina | 2,022 | |
Examining the interactive effect of posttraumatic stress disorder, distress tolerance, and gender on residential substance use disorder treatment retention. | An extensive body of research has demonstrated that patients with a co-occurring posttraumatic stress disorder (PTSD) and substance use disorder (SUD) diagnosis are at high risk for a wide range of negative clinical outcomes, including treatment noncompletion. However, no studies to date have explored the effect of a P... | 10.1037/a0029911 | 22,946,858 | D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D012114:Residential Treatment; D012737:Sex Factors; D013313:Stress Disorders, Post-Traumatic; D013315... | Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors | 2,013 | |
Critical review of long-term ozone exposure and asthma development. | Asthma, a chronic respiratory disorder with complex etiology and various phenotypes, is a considerable public health concern in the USA and worldwide. While there is evidence suggesting ambient ozone exposure may exacerbate asthma, information regarding the potential role of ozone in asthma development is more limited.... | 10.1080/08958378.2018.1455772 | 29,869,579 | D000393:Air Pollutants; D001249:Asthma; D004781:Environmental Exposure; D006801:Humans; D010126:Ozone | Inhalation toxicology | 2,018 | D000393:Air Pollutants; D010126:Ozone |
[Chemical constituents from stems and leaves of Psychotria serpens]. | The chemical consituents from the stems and leaves of Psychotria serpens were separated and purified by column chromatographies with silica gel, ODS, Sephadex LH-20 and PR-HPLC. The structures of the isolated compounds were identified on the basis of physicochemical properties and spectroscopic analyses, as well as com... | 10.19540/j.cnki.cjcmm.20180912.003 | 30,717,534 | D004365:Drugs, Chinese Herbal; D018515:Plant Leaves; D018547:Plant Stems; D032069:Psychotria | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | 2,018 | D004365:Drugs, Chinese Herbal |
Strain-dependent expression of four structurally related rat Ly49 receptors; correlation with NK gene complex haplotype and NK alloreactivity. | Natural killer (NK) cells from certain rat strains promptly kill MHC allogeneic lymphocytes in vivo, a rejection phenomenon termed allogeneic lymphocyte cytotoxicity (ALC). ALC can be reproduced in vitro, and is preferentially mediated by a subset of NK cells expressing the Ly49 stimulatory receptor 3 (Ly49s3) in PVG s... | 10.1007/s00251-006-0154-x | 17,028,855 | D000595:Amino Acid Sequence; D000818:Animals; D000911:Antibodies, Monoclonal; D000950:Antigens, Ly; D006239:Haplotypes; D015395:Histocompatibility Antigens Class I; D007694:Killer Cells, Natural; D037181:Lectins, C-Type; D008024:Ligands; D008969:Molecular Sequence Data; D012150:Polymorphism, Restriction Fragment Length... | Immunogenetics | 2,006 | D000911:Antibodies, Monoclonal; D000950:Antigens, Ly; D015395:Histocompatibility Antigens Class I; D037181:Lectins, C-Type; D008024:Ligands; D055630:Receptors, NK Cell Lectin-Like |
A Pilot Study to Assess the Feasibility of the Spanish Diabetes Self-Management Program in the Basque Country. | Purpose. The purpose of this study was to assess the feasibility of the Spanish Diabetes Self-Management Program (SDSMP) in the primary care setting of the Basque Health Service and offer initial estimations of the randomized controlled trial (RCT) effects. Methods. Ten health centers (HCs) participated in a single-arm... | 10.1155/2016/9145673 | 28,119,932 | D000368:Aged; D001794:Blood Pressure; D002318:Cardiovascular Diseases; D003924:Diabetes Mellitus, Type 2; D004032:Diet; D015444:Exercise; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006442:Glycated Hemoglobin; D015438:Health Behavior; D006801:Humans; D008297:Male; D008875:Middle Aged; D0108... | Journal of diabetes research | 2,016 | D006442:Glycated Hemoglobin A; C517652:hemoglobin A1c protein, human |
Performance of the Moorfields motion displacement test for identifying eyes with glaucoma. | PURPOSE
The Moorfields Motion Displacement Test (MMDT; Enhanced Standard Threshold Algorithm [ESTA] version 1, London, UK) is a new 31-point suprathreshold test for visual field assessment using moving line stimuli displayed on a standard laptop computer. This study evaluated the diagnostic performance of the MMDT for ... | 10.1016/j.ophtha.2013.08.036 | 24,139,154 | D000368:Aged; D005189:False Positive Reactions; D005260:Female; D015812:Glaucoma, Angle-Closure; D005902:Glaucoma, Open-Angle; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers; D009887:Ophthalmoscopy; D009901:Optic Nerve Diseases; D011237:Predictive Value of Tests; D011446:Prospective Studies; D0... | Ophthalmology | 2,014 | |
Cysteinesulfonate and beta-sulfopyruvate metabolism. Partitioning between decarboxylation, transamination, and reduction pathways. | L-Cysteinesulfonate (L-cysteate) is present in plasma, urine, and tissues in concentrations comparable to that of L-cysteinesulfinate, the primary oxidative metabolite of L-cysteine. Although cysteinesulfonate is known to be decarboxylated to taurine by cysteinesulfinate decarboxylase, the occurrence and importance of ... | 3,346,220 | D000818:Animals; D001219:Aspartate Aminotransferases; D001711:Biotransformation; D002250:Carbon Radioisotopes; D003545:Cysteine; D007527:Isoenzymes; D007700:Kinetics; D051379:Mice; D010084:Oxidation-Reduction; D011773:Pyruvates; D013379:Substrate Specificity | The Journal of biological chemistry | 1,988 | D002250:Carbon Radioisotopes; D007527:Isoenzymes; D011773:Pyruvates; C011119:S-sulphocysteine; C049788:beta-sulfopyruvic acid; D001219:Aspartate Aminotransferases; D003545:Cysteine | |
Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III. | Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells that ameliorates the diabetes of 90% depancreatized rats and non-obese diabetic mice. Reg and Reg-related genes have been revealed to constitute a multige... | 10.1016/j.gene.2004.06.010 | 15,556,304 | D024506:5' Flanking Region; D000595:Amino Acid Sequence; D001483:Base Sequence; D015152:Blotting, Northern; D002874:Chromosome Mapping; D002889:Chromosomes, Human, Pair 2; D003001:Cloning, Molecular; D004247:DNA; D018076:DNA, Complementary; D005260:Female; D020869:Gene Expression Profiling; D006801:Humans; D008297:Male... | Gene | 2,004 | D018076:DNA, Complementary; D000073718:Pancreatitis-Associated Proteins; D011506:Proteins; C000612141:REG3A protein, human; C494437:REG3G protein, human; D012333:RNA, Messenger; D004247:DNA |
An explanation of the dose inhomogeneity caused by bolus in an electron portal. | When an electron beam is incident upon a stepped surface, such as that which exists when a slab of bolus is present with it's square edge within the portal, the dose distribution is strikingly perturbed. An easily demonstrable explanation is given which utilizes the customary, flat-incident surface electron beam dose d... | 10.1118/1.596177 | 3,237,153 | D004583:Electrons; D006801:Humans; D008962:Models, Theoretical; D011878:Radiotherapy; D011879:Radiotherapy Dosage | Medical physics | 1,988 | |
Dynamic range of Nef-mediated evasion of HLA class II-restricted immune responses in early HIV-1 infection. | HLA class II-restricted CD4(+) T lymphocytes play an important role in controlling HIV-1 replication, especially in the acute/early infection stage. But, HIV-1 Nef counteracts this immune response by down-regulating HLA-DR and up-regulating the invariant chain associated with immature HLA-II (Ii). Although functional h... | 25,998,395 | D015658:HIV Infections; D015497:HIV-1; D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II; D006801:Humans; D057131:Immune Evasion; D054311:nef Gene Products, Human Immunodeficiency Virus | Biochemical and biophysical research communications | 2,015 | D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II; D054311:nef Gene Products, Human Immunodeficiency Virus | |
Activation of sirtuin1 protects against ischemia/reperfusion-induced acute kidney injury. | Sirtuin1 (SIRT1), a class III histone deacetylase, exerts a protective role against kidney injury. However, its functions in renal ischemia/reperfusion (I/R) injury remains unclear as yet. In this study, we established acute kidney injury (AKI) rat model through renal ischemia and reperfusion, and the role of SIRT1 in ... | 10.1016/j.biopha.2020.110021 | 32,092,826 | D058186:Acute Kidney Injury; D000818:Animals; D017209:Apoptosis; D001343:Autophagy; D004195:Disease Models, Animal; D004198:Disease Susceptibility; D004789:Enzyme Activation; D015870:Gene Expression; D006801:Humans; D007150:Immunohistochemistry; D007677:Kidney Function Tests; D007687:Kidney Tubules, Proximal; D008297:M... | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie | 2,020 | D020011:Protective Agents; D017382:Reactive Oxygen Species; D056564:Sirtuin 1 |
Epithelioid osteoblastoma. Clinicopathologic and immunohistochemical study of 17 cases. | Seventeen cases of epithelioid osteoblastoma were reviewed. The tumors most commonly arose from the vertebrae (7 cases), followed by the mandible (3), sacrum (2), bones of the foot (2), and femur, rib, and scapula (1 each). Patients' ages ranged from 5 to 33 years. The tumors measured from 2.0 to 6.5 cm in the greatest... | 10.1016/j.humpath.2022.03.006 | 35,337,839 | D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms; D002648:Child; D002675:Child, Preschool; D006801:Humans; D018215:Osteoblastoma; D055815:Young Adult | Human pathology | 2,022 | |
IQ heritability estimation: analyzing genetically-informative data with structural equation models. | When analyzing genetic data, Structural Equations Modeling (SEM) provides a straightforward methodology to decompose phenotypic variance using a model-based approach. Furthermore, several models can be easily implemented, tested, and compared using SEM, allowing the researcher to obtain valuable information about the s... | 17,295,998 | D006801:Humans; D007360:Intelligence; D008960:Models, Psychological; D014430:Twins, Monozygotic | Psicothema | 2,007 | ||
A novel mechanocatalytical reaction system driven by fluid shear force for the mild and rapid pretreatment of lignocellulosic biomass. | Pretreatment is the initial stage of lignocellulosic biorefinery process, but is limited by the time-consuming processes, harsh conditions and/or undesirable products. Herein, a mild (<60 °C) and highly efficient pretreatment strategy is developed. The novel mechanocatalytical reaction system driven by fluid shear forc... | 10.1016/j.wasman.2022.05.026 | 35,667,240 | D018533:Biomass; D002482:Cellulose; D057446:Hydrodynamics; D006868:Hydrolysis; D008031:Lignin | Waste management (New York, N.Y.) | 2,022 | C036909:lignocellulose; D002482:Cellulose; D008031:Lignin |
Barriers and facilitators to accessing insulin pump therapy by adults with type 1 diabetes mellitus: a qualitative study. | AIMS
Uptake of continuous subcutaneous insulin infusion (CSII) by people with diabetes (PwD) in Ireland is low and exhibits regional variation. This study explores barriers and facilitators to accessing CSII by adults with Type 1 diabetes mellitus.
RESEARCH DESIGN AND METHODS
A qualitative study employing focus group... | 10.1007/s00592-020-01595-5 | 32,862,261 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001364:Awareness; D003922:Diabetes Mellitus, Type 1; D004864:Equipment and Supplies; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006297:Health Services Accessibility; D006801:Humans; D007004:Hypoglycemic Agents; D007328:Ins... | Acta diabetologica | 2,021 | D007004:Hypoglycemic Agents; D007328:Insulin |
Is an isolated positive sonication fluid culture in revision arthroplasties clinically relevant? | OBJECTIVES
The aim of this study was to investigate the clinical relevance of an isolated positive sonication fluid culture (SFC) in patients who underwent revision surgery of a prosthetic joint. We hypothesized that cases with a positive SFC have a higher rate of infection during follow-up compared with controls with ... | 10.1016/j.cmi.2023.07.018 | 37,516,385 | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2,023 | ||
Production of a novel tryptophan analog, beta-1-indazole-L-alanine with tryptophan synthase of Escherichia coli. | The tryptophan synthase alpha 2 beta 2 complex from Escherichia coli has been found to catalyze the beta-replacement reaction of L-serine with indazole, an indole analog which has a nitrogen atom at the 2-position (pyrazole ring). The reaction product was isolated and identified as beta-indazolealanine by mass spectrom... | 10.1016/0014-5793(86)80279-4 | 3,512,296 | D055598:Chemical Phenomena; D002621:Chemistry; D004926:Escherichia coli; D007191:Indazoles; D009682:Magnetic Resonance Spectroscopy; D011720:Pyrazoles; D014364:Tryptophan; D014367:Tryptophan Synthase | FEBS letters | 1,986 | D007191:Indazoles; D011720:Pyrazoles; C047992:beta-1-indazolealanine; D014364:Tryptophan; D014367:Tryptophan Synthase |
Therapies for Preventing Heart Failure. | Heart failure is an increasingly common syndrome. Despite numerous advances in the treatment of patients with established heart failure, the prevalence and economic burden of the disease will continue to escalate as long as the number of patients with heart failure continues to increase. Much effort has been directed a... | 10.1007/s11936-003-0032-x | 12,834,570 | Current treatment options in cardiovascular medicine | 2,003 | ||
Safety and efficacy of escitalopram in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study. | PURPOSE
To evaluate the efficacy and safety of most selective serotonin reuptake inhibitor drug, escitalopram, in delaying ejaculation in patients with premature ejaculation (PE).
MATERIALS AND METHODS
A total of 276 married men (mean age, 34.4 years) with PE were randomly assigned to receive 10 mg of escitalopram (n... | 10.1097/jcp.0b013e31814b98d4 | 17,873,675 | D000284:Administration, Oral; D000328:Adult; D015283:Citalopram; D003075:Coitus; D004311:Double-Blind Method; D004542:Ejaculation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D017367:Selective Serotonin Reuptake Inhibitors; D012735:Sexual D... | Journal of clinical psychopharmacology | 2,007 | D017367:Serotonin Uptake Inhibitors; D015283:Citalopram |
Utility of Phenotypic and Genotypic Testing in the Study of Mycobacterium tuberculosis Resistance to First-Line Anti-Tuberculosis drugs. | OBJECTIVE
To determine the utility of molecular techniques in the diagnosis of resistance and the extent of resistance to first-line drugs in our region.
MATERIAL AND METHOD
From 2004 to 2013, 1,889 strains of Mycobacterium tuberculosis complex isolated in Asturias, Spain, were studied using phenotypic (Clinical and ... | 10.1016/j.arbres.2016.08.011 | 28,277,228 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000995:Antitubercular Agents; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009169:Mycobacterium tuberculosis; D0106... | Archivos de bronconeumologia | 2,017 | D000995:Antitubercular Agents |
[Recent concepts regarding the treatment of traumatic hemopneumothorax]. | BACKGROUND
The aim of the study was to examine the different therapeutic options for traumatic hemopneumothorax and in particular the latest concepts (videothoracoscopy).
METHODS
A retrospective study was performed on a group of 20 patients with post-traumatic hemothorax and/or pneumothorax attending the emergency de... | 11,568,723 | D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006491:Hemothorax; D006801:Humans; D008297:Male; D008875:Middle Aged; D011030:Pneumothorax; D013898:Thoracic Injuries; D013906:Thoracoscopy | Minerva chirurgica | 2,001 | ||
Use of recombinant ApxIV in serodiagnosis of Actinobacillus pleuropneumoniae infections, development and prevalidation of the ApxIV ELISA. | Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, which causes worldwide severe losses in pig farming. The virulence of the 15 serotypes of A. pleuropneumoniae is mainly determined by the three major RTX toxins ApxI, ApxII and ApxIII, which are secreted by the different serotypes in v... | 10.1016/j.vetmic.2004.01.004 | 15,066,725 | D000189:Actinobacillus Infections; D016977:Actinobacillus pleuropneumoniae; D000818:Animals; D001426:Bacterial Proteins; D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D005602:France; D007700:Kinetics; D011001:Pleuropneumonia; D011994:Recombinant Proteins; D012680:Sensitivity and Specificity; D01... | Veterinary microbiology | 2,004 | C122177:ApxIVA protein, Actinobacillus pleuropneumoniae; D001426:Bacterial Proteins; D011994:Recombinant Proteins |
Differential roles of tau class glutathione S-transferases in oxidative stress. | The plant glutathione S-transferase BI-GST has been identified as a potent inhibitor of Bax lethality in yeast, a phenotype associated with oxidative stress and disruption of mitochondrial functions. Screening of a tomato two-hybrid library for BI-GST interacting proteins identified five homologous Tau class GSTs, whic... | 10.1074/jbc.M309882200 | 15,037,622 | D000595:Amino Acid Sequence; D002384:Catalysis; D019281:Dimerization; D004305:Dose-Response Relationship, Drug; D005978:Glutathione; D019803:Glutathione Disulfide; D005982:Glutathione Transferase; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D018551:Solanum lycopersicum; D008958:Models, Molecular; D008969:Mole... | The Journal of biological chemistry | 2,004 | D016877:Oxidants; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D051028:bcl-2-Associated X Protein; D005982:Glutathione Transferase; D005978:Glutathione; D019803:Glutathione Disulfide |
Influence of weight classification on walking and jogging energy expenditure prediction in women. | The purpose of this study was to determine the influence of weight classification on predicting energy expenditure (EE) in women. Twelve overweight (body mass index [BMI] = 25-29.99 kg/m(2)) and 12 normal-weight (BMI = 18.5-24.99 kg/m(2)) women walked and jogged 1,609 m at 1.34 ms(-1) and 2.23 ms(-1), respectively, whi... | 10.1080/02701367.2012.10599873 | 22,978,188 | D000328:Adult; D015992:Body Mass Index; D002153:Calorimetry, Indirect; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D050177:Overweight; D012420:Running; D016138:Walking; D055815:Young Adult | Research quarterly for exercise and sport | 2,012 | |
[Evidence-based medicine in 2025--what will remain?]. | The reader is invited to attend a symposium on the long-term impact of Evidence-based Medicine (EBM) held in 2025. When EBM emerged for the first time, there had been great expectations, not all of which were fulfilled. Against the background of many vested interests evidence from clinical studies was not always welcom... | 12,891,975 | D019317:Evidence-Based Medicine; D006801:Humans; D011785:Quality Assurance, Health Care | Zeitschrift fur arztliche Fortbildung und Qualitatssicherung | 2,003 | ||
Phytotoxic Metabolites from Three Neofusicoccum Species Causal Agents of Botryosphaeria Dieback in Australia, Luteopyroxin, Neoanthraquinone, and Luteoxepinone, a Disubstituted Furo-α-pyrone, a Hexasubstituted Anthraquinone, and a Trisubstituted Oxepi-2-one from Neofusicoccum luteum. | Different phytotoxic metabolites were isolated from the organic extract of Neofusicoccum luteum, Neofusicoccum australe, and Neofusicoccum parvum, causal agents of Botryosphaeria dieback in Australia. N. luteum produced a new disubstituted furo-α-pyrone, a hexasubstituted anthraquinone, and a trisubstituted oxepi-2(7H)... | 10.1021/acs.jnatprod.9b01057 | 31,951,128 | D000880:Anthraquinones; D001203:Ascomycota; D049934:Isocoumarins; D015394:Molecular Structure; D009793:Ochratoxins; D018515:Plant Leaves; D011753:Pyrones; D021241:Spectrometry, Mass, Electrospray Ionization; D014118:Toxins, Biological | Journal of natural products | 2,020 | C000600633:4-hydroxymellein; D000880:Anthraquinones; D049934:Isocoumarins; D009793:Ochratoxins; D011753:Pyrones; D014118:Toxins, Biological; C042834:9,10-anthraquinone; C120538:ochracin |
Medical student education in the Department of Surgery at the University of Mississippi Medical Center in the 21st Century. | The approach of the Department of Surgery at the University of Mississippi to the education of medical students is considerably different from that of earlier eras. An overview of the current strategies for medical student education adopted by the Department in recent years and the philosophies behind them is presented... | 25,790,640 | D000046:Academic Medical Centers; D004501:Education, Medical; D013502:General Surgery; D008922:Mississippi | Journal of the Mississippi State Medical Association | 2,014 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.