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An Robust Rank Aggregation and Least Absolute Shrinkage and Selection Operator Analysis of Novel Gene Signatures in Dilated Cardiomyopathy. | Objective: Dilated cardiomyopathy (DCM) is a heart disease with high mortality characterized by progressive cardiac dilation and myocardial contractility reduction. The molecular signature of dilated cardiomyopathy remains to be defined. Hence, seeking potential biomarkers and therapeutic of DCM is urgent and necessary... | 10.3389/fcvm.2021.747803 | 34,970,603 | Frontiers in cardiovascular medicine | 2,021 | ||
Dry powder coating of pharmaceuticals: a review. | Over the last half century, film coating technology has evolved significantly in terms of compositions and manufacturing processes, allowing for greater functionality, flexibility and efficiency. Driven by a combination of cost considerations and functionality, a range of dry powder coating technologies have been devel... | 23,428,881 | D002626:Chemistry, Pharmaceutical; D006358:Hot Temperature; D004364:Pharmaceutical Preparations; D011208:Powders; D055672:Static Electricity; D013678:Technology, Pharmaceutical | International journal of pharmaceutics | 2,013 | D004364:Pharmaceutical Preparations; D011208:Powders | |
Strong association between the HLA-Dw3-related B cell alloantigen -DRw3 and coeliac disease. | The frequency of HLA-A, -B, and -C antigens, of -DRw3 and the associated B-lymphocyte alloantigen -DRw3 has been studied in 68 children with coeliac disease (CD). CD was found to be primarily associated with the B-lymphocyte alloantigen, the relative risk being calculated to 54. The possible relation between the B-lymp... | 10.3109/00365527809181753 | 76,332 | D001402:B-Lymphocytes; D002446:Celiac Disease; D002648:Child; D000939:Epitopes; D006680:HLA Antigens; D006650:Histocompatibility Testing; D006801:Humans; D007519:Isoantigens | Scandinavian journal of gastroenterology | 1,978 | D000939:Epitopes; D006680:HLA Antigens; D007519:Isoantigens |
Uncovering genomic causes of co-morbidity in epilepsy: gene-driven phenotypic characterization of rare microdeletions. | BACKGROUND
Patients with epilepsy often suffer from other important conditions. The existence of such co-morbidities is frequently not recognized and their relationship with epilepsy usually remains unexplained.
METHODOLOGY/PRINCIPAL FINDINGS
We describe three patients with common, sporadic, non-syndromic epilepsies ... | 10.1371/journal.pone.0023182 | 21,858,020 | D000015:Abnormalities, Multiple; D000328:Adult; D002872:Chromosome Deletion; D025063:Chromosome Disorders; D002881:Chromosomes, Human, Pair 12; D002886:Chromosomes, Human, Pair 17; D002893:Chromosomes, Human, Pair 3; D015897:Comorbidity; D004827:Epilepsy; D005260:Female; D017353:Gene Deletion; D056726:Genetic Associati... | PloS one | 2,011 | |
The addition of peanuts to habitual diets is associated with lower consumption of savory non-core snacks by men and sweet non-core snacks by women. | Snacking is associated with intakes of non-core foods which may predispose to obesity. Peanuts have potential satiety benefits and may assist with weight management; we hypothesized that peanut consumption would reduce intake of non-core snack foods due to compensation. We investigated the effects of adding peanuts to ... | 10.1016/j.nutres.2017.04.005 | 28,506,518 | D000368:Aged; D010367:Arachis; D015992:Body Mass Index; D001835:Body Weight; D018592:Cross-Over Studies; D004032:Diet; D015930:Diet Records; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber; D004044:Dietary Proteins; D002149:Energy Intake; D004734:Energy Metabolism; D005260:Female; D006801:Hum... | Nutrition research (New York, N.Y.) | 2,017 | D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber; D004044:Dietary Proteins |
Extrahepatic biliary atresia. Morphological study of 98 biliary remnants. | Histologic examination was performed on 98 biliary remnants. Classification into three types was made according to the presence of epithelial structure; biliary and glandular formations had to be separated. Atretic lesions were predominantly observed at the pars inferior of the remnants. These histological findings agr... | 6,894,845 | D001646:Bile; D001652:Bile Ducts; D005704:Gallbladder; D006801:Humans; D007223:Infant | Archives of pathology & laboratory medicine | 1,981 | ||
Imaging angiogenesis using 68Ga-NOTA-PRGD2 positron emission tomography/computed tomography in patients with severe intracranial atherosclerotic disease. | Angiogenesis is a critical compensation route, which has been demonstrated in the brain following ischemic stroke; however, few studies have investigated angiogenesis in chronic intracranial atherosclerosis disease (ICAD). We used 68Ga-NOTA-PRGD2 positron emission tomography/computed tomography based imaging to detect ... | 10.1177/0271678X17696322 | 28,273,724 | D000328:Adult; D000368:Aged; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D005710:Gallium Radioisotopes; D006571:Heterocyclic Compounds; D006573:Heterocyclic Compounds, 1-Ring; D006801:Humans; D002537:Intracranial Arteriosclerosis; D008297:Male; D008875:Middle Aged; D064847:Multimodal... | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism | 2,017 | D005462:Fluorine Radioisotopes; D005710:Gallium Radioisotopes; D006571:Heterocyclic Compounds; D006573:Heterocyclic Compounds, 1-Ring; D019788:Fluorodeoxyglucose F18; C048993:1,4,7-triazacyclononane-N,N',N''-triacetic acid |
Interrogating the Venom of the Viperid Snake Sistrurus catenatus edwardsii by a Combined Approach of Electrospray and MALDI Mass Spectrometry. | The complete sequence characterization of snake venom proteins by mass spectrometry is rather challenging due to the presence of multiple isoforms from different protein families. In the present study, we investigated the tryptic digest of the venom of the viperid snake Sistrurus catenatus edwardsii by a combined appro... | 10.1371/journal.pone.0092091 | 25,955,844 | D000595:Amino Acid Sequence; D000818:Animals; D008666:Metalloendopeptidases; D008969:Molecular Sequence Data; D040901:Proteomics; D030162:Reptilian Proteins; D016415:Sequence Alignment; D057057:Serine Proteases; D021241:Spectrometry, Mass, Electrospray Ionization; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desor... | PloS one | 2,015 | D030162:Reptilian Proteins; D014757:Viper Venoms; D057057:Serine Proteases; D008666:Metalloendopeptidases |
Soil moisture-atmosphere feedback dominates land N2 O nitrification emissions and denitrification reduction. | Soil moisture (SM) is essential to microbial nitrogen (N)-cycling networks in terrestrial ecosystems. Studies have found that SM-atmosphere feedbacks dominate the changes in land carbon fluxes. However, the influence of SM-atmosphere feedbacks on the N fluxes changes, and the underlying mechanisms remain highly unsure,... | 10.1111/gcb.16365 | 35,971,257 | D001272:Atmosphere; D002244:Carbon; D058440:Denitrification; D017753:Ecosystem; D005246:Feedback; D058465:Nitrification; D009584:Nitrogen; D009609:Nitrous Oxide; D012987:Soil; D014867:Water | Global change biology | 2,022 | D012987:Soil; D014867:Water; D002244:Carbon; D009609:Nitrous Oxide; D009584:Nitrogen |
Biochemical markers of vitamin B12 deficiency combined in one diagnostic parameter: the age-dependence and association with cognitive function and blood hemoglobin. | BACKGROUND
Vitamin B12 deficiency is diagnosed by measurements of total B12, holo-transcobalamin (holoTC), methylmalonic acid (MMA) and total homocysteine (Hcy) in blood. Results of the individual biochemical tests are often contradictory. Here the four markers are combined to achieve a more reliable indication of the ... | 23,583,557 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D015415:Biomarkers; D003071:Cognition; D003072:Cognition Disorders; D006454:Hemoglobins; D006801:Humans; D008875:Middle Aged; D014806:Vitamin B 12 Deficiency; D055815:Young Adult | Clinica chimica acta; international journal of clinical chemistry | 2,013 | D015415:Biomarkers; D006454:Hemoglobins | |
An Innovative Modular eNose System Based on a Unique Combination of Analog and Digital Metal Oxide Sensors. | An innovative concept for an electronic nose (eNose) system based on a unique combination of analog and digital sensors for online monitoring is presented. The developed system consists of small sensing arrays of commercially available semiconducting metal oxide (MOX) gas sensors in a compact, modular, low sample volum... | 10.1021/acssensors.9b01244 | 31,389,228 | D002623:Chemistry Techniques, Analytical; D062609:Electronic Nose; D005740:Gases; D008670:Metals; D010087:Oxides | ACS sensors | 2,019 | D005740:Gases; D008670:Metals; D010087:Oxides |
Accurate T(1) mapping for oxygen-enhanced MRI in the mouse lung using a segmented inversion-recovery ultrashort echo-time sequence. | PURPOSE
A segmented inversion-recovery module combined with the 2D ultrashort echo time radial technique is proposed that allows accurate pixel level T(1) mapping of mouse lung in vivo.
METHODS
Numerical simulations were performed to estimate T(1) measurement accuracy and precision versus flip angle and signal-to-noi... | 10.1002/mrm.24876 | 23,878,094 | D000465:Algorithms; D000818:Animals; D003198:Computer Simulation; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D008168:Lung; D008279:Magnetic Resonance Imaging; D051379:Mice; D008810:Mice, Inbred C57BL; D010100:Oxygen; D019047:Phantoms, Imaging | Magnetic resonance in medicine | 2,014 | D010100:Oxygen |
A luminescent and mesoporous core-shell structured Gd2O3 : Eu(3+)@nSiO2@mSiO2 nanocomposite as a drug carrier. | In this paper, Gd(2)O(3) : Eu(3+) nanospheres have been encapsulated with nonporous silica and further layer of ordered mesoporous silica through a simple sol-gel process. X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), N(2) adsorption/desorption, photoluminescence (... | 10.1039/c1dt10162e | 21,431,226 | D004317:Doxorubicin; D004337:Drug Carriers; D005063:Europium; D005682:Gadolinium; D005782:Gels; D006367:HeLa Cells; D006801:Humans; D018613:Microscopy, Confocal; D053761:Nanocomposites; D016062:Porosity; D012822:Silicon Dioxide | Dalton transactions (Cambridge, England : 2003) | 2,011 | D004337:Drug Carriers; D005782:Gels; D005063:Europium; C030581:gadolinium oxide; D012822:Silicon Dioxide; D004317:Doxorubicin; D005682:Gadolinium |
Attention deficits: is there a right hemisphere specialization for simple reaction time, sustained attention, and phasic alertness? | Impairments of attentional focus often are claimed to be associated with lesions of the right hemisphere. Although some studies comparing right- and left-brain-damaged patients have supported this idea, others have not found differences between these patients in various attention tasks. The present study was carried ou... | 10.1006/brcg.1999.1133 | 10,857,655 | D000328:Adult; D000368:Aged; D001143:Arousal; D001288:Attention; D001930:Brain Injuries; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time | Brain and cognition | 2,000 | |
Potential challenges of using narrative inquiry with at-risk young people. | BACKGROUND
Being 'at risk' puts an individual in danger of future negative outcomes. Conducting qualitative research such as narrative inquiry with at-risk individuals may result in challenges for participants and researchers.
AIM
To present an overview of several challenges that arose when conducting narrative resea... | 10.7748/nr.2019.e1619 | 31,468,924 | Nurse researcher | 2,019 | ||
Functional Genes and Bacterial Communities During Organohalide Respiration of Chloroethenes in Microcosms of Multi-Contaminated Groundwater. | Microcosm experiments with CE-contaminated groundwater from a former industrial site were set-up to evaluate the relationships between biological CE dissipation, dehalogenase genes abundance and bacterial genera diversity. Impact of high concentrations of PCE on organohalide respiration was also evaluated. Complete or ... | 10.3389/fmicb.2019.00089 | 30,809,199 | Frontiers in microbiology | 2,019 | ||
Rapid and specific isolation of radioactive glucose from biological samples. | An easy, reliable, and specific ion-exchange method is presented for isolating glucose for specific radioactivity determinations from both blood plasma and buffered in vitro incubation media. The use of a glucose binding resin (borate-charged anion resin) combined speed of ion exchange with specificity of derivative fo... | 10.3168/jds.S0022-0302(81)82752-X | 7,298,970 | D000818:Animals; D005947:Glucose; D007474:Ion Exchange; D011868:Radioisotopes | Journal of dairy science | 1,981 | D011868:Radioisotopes; D005947:Glucose |
The Past and Future of Psychedelic Science: An Introduction to This Issue. | Psychedelic plants and fungi have been used in indigenous medicinal traditions for millennia. Modern psychedelic research began when Albert Hofmann first synthesized lysergic acid diethylamide (LSD-25) in 1938. Five years later, became the first person to ingest LSD. Hofmann was unaware of the significance of his actio... | 10.1080/02791072.2019.1606472 | 31,132,970 | D035843:Biomedical Research; D006213:Hallucinogens; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008238:Lysergic Acid Diethylamide; D001523:Mental Disorders; D018817:N-Methyl-3,4-methylenedioxyamphetamine; D011562:Psilocybin | Journal of psychoactive drugs | 2,019 | D006213:Hallucinogens; D011562:Psilocybin; D008238:Lysergic Acid Diethylamide; D018817:N-Methyl-3,4-methylenedioxyamphetamine |
Liquid biopsy: Novel perspectives on the importance and spectrum of PIK3CA, PTEN and RET mutations in solid tumors. | Many people die from lung and breast cancer. Consequently, both physicians and researchers strive to provide reliable monitoring for disease, diagnosis and prognosis as well as resistance prediction. In the present study, a comprehensive liquid biopsy panel was performed on 474 patients to examine the importance and sp... | 10.3892/mco.2021.2434 | 34,824,841 | Molecular and clinical oncology | 2,022 | ||
Conservation and diversity among the three-dimensional folds of the Dicistroviridae intergenic region IRESes. | Internal ribosome entry site (IRES) RNAs are necessary for successful infection of many pathogenic viruses, but the details of the RNA structure-based mechanism used to bind and manipulate the ribosome remain poorly understood. The IRES RNAs from the Dicistroviridae intergenic region (IGR) are an excellent model system... | 10.1016/j.jmb.2007.04.076 | 17,544,444 | D001483:Base Sequence; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012328:RNA Viruses; D012367:RNA, Viral; D012270:Ribosomes | Journal of molecular biology | 2,007 | D012367:RNA, Viral |
Mediastinal paraganglioma: time to panic? | Paragangliomas (extra-adrenal phaeochromocytomas) are tumours arising from extra-adrenal chromaffin tissue. The authors describe a case of a 54-year-old woman presenting with shortness of breath and chest pain. CT pulmonary angiogram demonstrated a mediastinal mass. Further history taking revealed spontaneous attacks o... | 22,707,541 | D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms; D008875:Middle Aged; D010235:Paraganglioma | BMJ case reports | 2,011 | ||
Spatial cognition following early-life seizures in rats: Performance deficits are dependent on task demands. | Cognitive impairment is a common comorbidity in childhood epilepsy. Studies in rodents have demonstrated that frequent seizures during the first weeks of life result in impaired spatial cognition when the rats are tested as juvenile or adults. To determine if spatial cognitive deficits following early-life seizures are... | 10.1016/j.yebeh.2016.03.032 | 27,152,463 | D000679:Amygdala; D000818:Animals; D001362:Avoidance Learning; D003071:Cognition; D003072:Cognition Disorders; D004597:Electroshock; D006624:Hippocampus; D008297:Male; D018782:Maze Learning; D009186:Myelin Sheath; D009415:Nerve Net; D051381:Rats; D017207:Rats, Sprague-Dawley; D012640:Seizures; D013028:Space Perception;... | Epilepsy & behavior : E&B | 2,016 | |
Variance in the reproductive success of flat oyster Ostrea edulis L. assessed by parentage analyses in natural and experimental conditions. | In order to document further the phenomena of variance in reproductive success in natural populations of the European flat oyster Ostrea edulis, two complementary studies based on natural and experimental populations were conducted. The first part of this work was focused on paternity analyses using a set of four micro... | 10.1017/S0016672310000248 | 20,667,162 | D000818:Animals; D005260:Female; D005602:France; D014644:Genetic Variation; D007814:Larva; D008297:Male; D018895:Microsatellite Repeats; D049895:Ostrea; D010375:Pedigree; D012098:Reproduction | Genetics research | 2,010 | |
Deciphering the Intercellular Communication Network of Peripartum Decidua that Orchestrates Delivery. | Intercellular communication in the decidua plays important roles in relaying information between the maternal and fetal systems in the maintenance of pregnancy and the transition to labor. To date, several studies have explored cell-cell communications in the decidua during different periods of pregnancy, but studies s... | 10.3389/fcell.2021.770621 | 34,805,176 | Frontiers in cell and developmental biology | 2,021 | ||
The sensitive to freezing3 mutation of Arabidopsis thaliana is a cold-sensitive allele of homomeric acetyl-CoA carboxylase that results in cold-induced cuticle deficiencies. | The sfr3 mutation causes freezing sensitivity in Arabidopsis thaliana. Mapping, sequencing, and transgenic complementation showed sfr3 to be a missense mutation in ACC1, an essential gene encoding homomeric (multifunctional) acetyl-CoA carboxylase. Cuticle permeability was compromised in the sfr3 mutant when plants wer... | 10.1093/jxb/ers191 | 22,791,831 | D000064:Acclimatization; D000103:Acetyl-CoA Carboxylase; D000595:Amino Acid Sequence; D017360:Arabidopsis; D029681:Arabidopsis Proteins; D002874:Chromosome Mapping; D003080:Cold Temperature; D018506:Gene Expression Regulation, Plant; D009154:Mutation; D010641:Phenotype; D018515:Plant Leaves; D016415:Sequence Alignment;... | Journal of experimental botany | 2,012 | D029681:Arabidopsis Proteins; D000103:Acetyl-CoA Carboxylase |
Discovery of Sibiriline derivatives as novel receptor-interacting protein kinase 1 inhibitors. | Receptor-interacting protein kinase 1 (RIPK1), a vital protein of the necroptosis pathway, plays a pivotal role in various inflammatory diseases. Sibiriline has been reported to be a potent ATP-competitive RIPK1 inhibitor, but its anti-necroptotic effects are limited. A series of structural analogues of Sibiriline were... | 10.1016/j.ejmech.2023.115190 | 36,801,518 | D000818:Animals; D051379:Mice; D017209:Apoptosis; D010766:Phosphorylation; D013329:Structure-Activity Relationship; D011494:Protein Kinases; D047428:Protein Kinase Inhibitors; D053422:Receptor-Interacting Protein Serine-Threonine Kinases | European journal of medicinal chemistry | 2,023 | D011494:Protein Kinases; D047428:Protein Kinase Inhibitors; D053422:Receptor-Interacting Protein Serine-Threonine Kinases |
Properties of bipolar VIPergic interneurons and their excitation by pyramidal neurons in the rat neocortex. | In the rat neocortex, a subset of GABAergic interneurons express the neuropeptide vasoactive intestinal peptide (VIP). Previously, we demonstrated that a population of VIPergic interneurons could be accurately identified by their irregular spiking (IS) pattern and their bipolar morphology. IS interneurons were studied ... | 10.1046/j.1460-9568.1998.00367.x | 9,875,341 | D000200:Action Potentials; D000818:Animals; D002450:Cell Communication; D017931:DNA Primers; D015870:Gene Expression; D007395:Interneurons; D019579:Neocortex; D018408:Patch-Clamp Techniques; D017966:Pyramidal Cells; D051381:Rats; D017208:Rats, Wistar; D017470:Receptors, Glutamate; D013569:Synapses; D014660:Vasoactive I... | The European journal of neuroscience | 1,998 | D017931:DNA Primers; D017470:Receptors, Glutamate; D014660:Vasoactive Intestinal Peptide |
Comparison of the dental health status of six-year-old children in Manitoba. | The caries rates of six-year-old Manitoba children from a non-fluoridated Northern community were compared with those of a representative group of southern Manitoba children from non-fluoridated areas. All of the surveyed children became eligible for dental treatment coverage under Manitoba Health's Children's Dental P... | 8,513,420 | D000704:Analysis of Variance; D016009:Chi-Square Distribution; D002648:Child; D004245:DMF Index; D003731:Dental Caries; D005260:Female; D005457:Fluoridation; D006301:Health Services Needs and Demand; D006801:Humans; D007182:Income; D007347:Insurance, Dental; D008297:Male; D008350:Manitoba; D012111:Residence Characteris... | Journal (Canadian Dental Association) | 1,993 | ||
Overall mortality after radical nephrectomy in patients aged over 80 years with renal cancer: a retrospective study on preoperative prognostic factors. | OBJECTIVES
To evaluate the overall survival postnephrectomy for renal cancer for patients aged over 80 years, and to identify preoperative prognostic factors that might influence therapeutic strategies.
METHODS
In a retrospective study in five French departments of urology, 179 patients aged over 80 years with renal ... | 10.1111/j.1442-2042.2012.03006.x | 22,458,762 | D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell; D015897:Comorbidity; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D007680:Kidney Neoplasms; D008207:Lymphatic Metastasis; D008297:Male; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D009392:Nephrectomy;... | International journal of urology : official journal of the Japanese Urological Association | 2,012 | |
Principles and technique of foam sclerotherapy and its specific use in the treatment of venous leg ulcers. | Invention of foam sclerotherapy has significantly changed the current phlebological practice. Compared with liquid sclerosants, obliterating foam is more efficient, especially for the closure of larger veins. This review discusses clinical aspects of foam sclerotherapy with a focus on its use for the treatment of venou... | 10.1177/1534734611418154 | 21,856,975 | D002245:Carbon Dioxide; D002908:Chronic Disease; D006801:Humans; D010100:Oxygen; D010690:Phlebography; D015911:Sclerotherapy; D014647:Varicose Ulcer | The international journal of lower extremity wounds | 2,011 | D002245:Carbon Dioxide; D010100:Oxygen |
Evaluation results from prospective drug utilization review: Medicaid demonstrations. | In 1992 HCFA awarded two cooperative agreements for demonstrations of prospective drug utilization review (PDUR). Iowa tested an on-line prospective drug utilization review (OPDUR) system. Washington tested payments to pharmacists for providing non-dispensing "cognitive services" (CS). In this article the authors repor... | 10,558,015 | D014487:Centers for Medicare and Medicaid Services, U.S.; D003365:Costs and Cost Analysis; D003625:Data Collection; D017723:Drug Utilization Review; D064420:Drug-Related Side Effects and Adverse Reactions; D005069:Evaluation Studies as Topic; D007349:Insurance, Health, Reimbursement; D007484:Iowa; D008484:Medicaid; D01... | Health care financing review | 1,999 | ||
From development to cancer: lessons from the kidney to uncover new therapeutic targets. | Several genes play essential roles in human development and alteration of their expression or regulation leads to various pathologies. This review examines the literature on the expression and the roles of neurogenic locus notch homolog protein (NOTCH), sonic Hedgehog (SHH) and wingless-type (WNT) pathways, as well as ... | 22,993,298 | D018262:Adenocarcinoma, Clear Cell; D000818:Animals; D002292:Carcinoma, Renal Cell; D002471:Cell Transformation, Neoplastic; D053823:Hedgehog Proteins; D006801:Humans; D007668:Kidney; D007680:Kidney Neoplasms; D060850:LIM-Homeodomain Proteins; D058990:Molecular Targeted Therapy; D051762:PAX2 Transcription Factor; D0518... | Anticancer research | 2,012 | D053823:Hedgehog Proteins; D060850:LIM-Homeodomain Proteins; D051762:PAX2 Transcription Factor; D051880:Receptors, Notch; D025721:WT1 Proteins; D051153:Wnt Proteins | |
Cholescintigraphy: gallbladder nonvisualization secondary to neoplasm. | Whereas the diagnosis of acute cholecystitis is characterized by nonvisualization of the gallbladder with Tc-99m iminodiacetic acid derivatives, nonvisualization is not specific for acute cholecystitis. The first reported case of nonvisualization of the gallbladder due to neoplasm is added to an expanding list of cause... | 7,264,758 | D000230:Adenocarcinoma; D002763:Cholecystectomy; D002764:Cholecystitis; D003138:Common Bile Duct Neoplasms; D005260:Female; D005704:Gallbladder; D005706:Gallbladder Neoplasms; D006801:Humans; D007098:Imino Acids; D008099:Liver; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D0136... | Journal of nuclear medicine : official publication, Society of Nuclear Medicine | 1,981 | D007098:Imino Acids; D015609:Organotechnetium Compounds; D013667:Technetium; C003693:technetium Tc 99m PIPIDA | |
Location and electrophysiological characterization of rostral medullary adrenergic neurons that contain neuropeptide Y mRNA in rat medulla. | The objective of this study was to characterize the projection pattern and electrophysiological properties of the rostral medullary adrenergic neurons (C(1)) that express neuropeptide Y (NPY) mRNA in rat. NPY mRNA was found in a variable fraction of tyrosine hydroxylase immunoreactive (TH-IR) neurons depending on the m... | 10.1002/(sici)1096-9861(19991227)415:4<482::aid-cne5>3.0.co;2-4 | 10,570,457 | D000320:Adrenergic Fibers; D000818:Animals; D001794:Blood Pressure; D001931:Brain Mapping; D004837:Epinephrine; D007031:Hypothalamus; D008297:Male; D008526:Medulla Oblongata; D009434:Neural Pathways; D009474:Neurons; D009478:Neuropeptide Y; D010641:Phenotype; D011311:Pressoreceptors; D012333:RNA, Messenger; D051381:Rat... | The Journal of comparative neurology | 1,999 | D009478:Neuropeptide Y; D012333:RNA, Messenger; D004837:Epinephrine |
(S)-3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(piperazin-1-yl) propanoic acid compounds: synthesis and biological evaluation of dual PPARalpha/gamma agonists. | A series of novel, potent PPARalpha/gamma dual agonists were synthesized and appraised. The most potent analogue, compound 2b demonstrated EC(50) value of 0.012+/-0.002 and 0.032+/-0.01 microM, respectively, for hPPARalpha and hPPARgamma in transactivation assay. Additionally, compound 2b demonstrated good glucose and ... | 10.1016/j.bmcl.2010.02.071 | 20,299,214 | D000818:Animals; D001786:Blood Glucose; D003921:Diabetes Mellitus, Experimental; D008055:Lipids; D051379:Mice; D047493:PPAR alpha; D047495:PPAR gamma; D011422:Propionates | Bioorganic & medicinal chemistry letters | 2,010 | D001786:Blood Glucose; D008055:Lipids; D047493:PPAR alpha; D047495:PPAR gamma; D011422:Propionates; C029658:propionic acid |
MicroRNA-210 May Be a Preoperative Biomarker of Malignant Pheochromocytomas and Paragangliomas. | BACKGROUND
Currently, no reliable predictive clinical or laboratory tests exist that can accurately distinguish between benign and malignant pheochromocytomas or paragangliomas (PPGLs). The aim of this study was to investigate if serum microRNA-210 (miR-210) levels could be a marker of malignancy in patients with PPGLs... | 10.1016/j.jss.2019.04.086 | 31,146,085 | D000310:Adrenal Gland Neoplasms; D000328:Adult; D014408:Biomarkers, Tumor; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D035683:MicroRNAs; D008875:Middle Aged; D010235:Paraganglioma; D010673:Pheochromocytoma; D010865:Pilot Projects; D011300:Preoperative Care; D057234... | The Journal of surgical research | 2,019 | D014408:Biomarkers, Tumor; C543800:MIRN210 microRNA, human; D035683:MicroRNAs |
Interleukin 4 is at 5q31 and interleukin 6 is at 7p15. | DNA probes to the human interleukin 4 (IL4) and interleukin 6 (IL6) genes have been used for in situ hybridization to normal human chromosomes and Southern blot analysis of a series of mouse-human hybrid cell lines. IL4 maps to 5q31, the same location as IL5 and other haemopoietic growth factor genes. IL6 maps to 7p15.... | 10.1007/BF00282171 | 3,261,707 | D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D006822:Hybrid Cells; D015847:Interleukin-4; D015850:Interleukin-6; D007378:Interleukins; D009693:Nucleic Acid Hybridization | Human genetics | 1,988 | D015850:Interleukin-6; D007378:Interleukins; D015847:Interleukin-4 |
[Variations in the phagocytic potency of circulating leukocytes from rats which received a thermal injury. Effects of an immunostimulation with Corynebacterium granulosum (author's transl)]. | Experiments were carried out to study in vitro the variations of phagocytic activity of circulating leukocytes from rats which received a thermal injury and were either immunostimulated or not by a single iv injection of C. granulosum. The thermal injury which was applied at about 10 percent of the body surface was of ... | 370,744 | D000818:Animals; D001428:Bacterial Vaccines; D002056:Burns; D003352:Corynebacterium; D007962:Leukocytes; D008297:Male; D010587:Phagocytosis; D051381:Rats | Pathologie-biologie | 1,978 | D001428:Bacterial Vaccines | |
Effect of phospholipase A2 on temperature-induced high-affinity [3H]tryptamine binding sites in rat brain. | To investigate a link between membrane phospholipids and tryptamine binding molecules, we examined the effects of phospholipases A2 and D on the temperature-sensitive high-affinity [3H]tryptamine binding sites in rat brain. When the phospholipase A2-treated membranes were exposed to 1% bovine serum albumin (BSA) before... | 10.1254/jjp.56.413 | 1,744,985 | D000818:Animals; D001665:Binding Sites; D001921:Brain; D004305:Dose-Response Relationship, Drug; D008297:Male; D008563:Membrane Lipids; D010713:Phosphatidylcholines; D010718:Phosphatidylserines; D010739:Phospholipase D; D010741:Phospholipases A; D054467:Phospholipases A2; D010743:Phospholipids; D051381:Rats; D011919:Ra... | Japanese journal of pharmacology | 1,991 | D008563:Membrane Lipids; D010713:Phosphatidylcholines; D010718:Phosphatidylserines; D010743:Phospholipids; D014363:Tryptamines; C030820:tryptamine; D010741:Phospholipases A; D054467:Phospholipases A2; D010739:Phospholipase D |
Tumor mapping of regional immunostaining for p21, p53, and mdm2 in locally advanced bladder carcinoma. | BACKGROUND
The aim of this study was to elucidate the associations among immunostaining for p53, p21, and mdm2; their respective expression within each tumor; and the value of these variables for predicting treatment outcome after cystectomy for patients with locally advanced bladder carcinoma.
METHODS
The hospital r... | 10,931,462 | D000328:Adult; D000368:Aged; D050759:Cyclin-Dependent Kinase Inhibitor p21; D016213:Cyclins; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D011379:Prognosis; D016016:Proportional Hazards Models; D011518:Proto-Oncogen... | Cancer | 2,000 | C493956:CDKN1A protein, human; D050759:Cyclin-Dependent Kinase Inhibitor p21; D016213:Cyclins; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; D016159:Tumor Suppressor Protein p53; C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2 | |
Effects of aromatase or estrogen receptor gene deletion on masculinization of the principal nucleus of the bed nucleus of the stria terminalis of mice. | The principal nucleus of the bed nucleus of the stria terminalis (BNSTp) is a sexually dimorphic nucleus, and the male BNSTp is larger and has more neurons than the female BNSTp. To assess the roles of neuroestrogen synthesized from testicular androgen by brain aromatase in masculinization of the BNSTp, we performed mo... | 10.1159/000327541 | 21,525,731 | D000818:Animals; D001141:Aromatase; D002452:Cell Count; D004797:Enzyme-Linked Immunosorbent Assay; D047628:Estrogen Receptor alpha; D047629:Estrogen Receptor beta; D005260:Female; D017353:Gene Deletion; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D009457:Neuroglia; D009474:Neurons; D011960:Receptors, Estrogen; ... | Neuroendocrinology | 2,011 | D047628:Estrogen Receptor alpha; D047629:Estrogen Receptor beta; D011960:Receptors, Estrogen; D013739:Testosterone; D001141:Aromatase |
Quantitative phosphoproteomic analysis identifies the potential therapeutic target EphA2 for overcoming sorafenib resistance in hepatocellular carcinoma cells. | Limited therapeutic options are available for advanced-stage hepatocellular carcinoma owing to its poor diagnosis. Drug resistance to sorafenib, the only available targeted agent, is commonly reported. The comprehensive elucidation of the mechanisms underlying sorafenib resistance may thus aid in the development of mor... | 10.1038/s12276-020-0404-2 | 32,203,105 | D000818:Animals; D006528:Carcinoma, Hepatocellular; D002448:Cell Adhesion; D045744:Cell Line, Tumor; D002465:Cell Movement; D049109:Cell Proliferation; D004195:Disease Models, Animal; D019008:Drug Resistance, Neoplasm; D006801:Humans; D008113:Liver Neoplasms; D051379:Mice; D010750:Phosphoproteins; D040901:Proteomics; D... | Experimental & molecular medicine | 2,020 | C000623258:EPHA2 protein, human; D010750:Phosphoproteins; D000077157:Sorafenib; D036104:Receptor, EphA2 |
The effect of frequency tolerance on audiometer accuracy. | Investigations into the methods used to calibrate audiometers reveal that the 6 000 Hz frequency is particularly liable to yield inconsistent results when calibrated in the usual way. It is shown that the TDH39 telephone receiver which is usually calibrated on a 9A coupler in accordance with the International Standards... | 609,969 | D001299:Audiometry; D004431:Ear, External; D006801:Humans; D013016:Sound; D013689:Telephone | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde | 1,977 | ||
Virtual Outreach: Using Social Media to Reach Spanish-speaking Agricultural Workers during the COVID-19 Pandemic. | Face-to-face outreach and in-person training have traditionally been key strategies in reaching agricultural producers, workers, and communities with safety and health information, but the COVID-19 pandemic has forced outreach educators to be creative and find alternative ways to reach, communicate, and share such info... | 10.1080/1059924X.2020.1814919 | 32,921,289 | D000086382:COVID-19; D003142:Communication; D000067565:Farmers; D006266:Health Education; D006630:Hispanic or Latino; D006801:Humans; D007802:Language; D016272:Occupational Health; D058873:Pandemics; D061108:Social Media; D014584:User-Computer Interface | Journal of agromedicine | 2,020 | |
Predicting pregnancy from pregnancy intentions: prospective findings from the Central Pennsylvania Womens's Heath Study (CePAWHS). | OBJECTIVE
We examined whether adult women's intention for future pregnancy predicted actual pregnancies occurring in a 2-year follow-up study.
METHODS
Data are from the Central Pennsylvania Women's Health Study population-based longitudinal survey of women ages 18-45 (n = 1,420). The analytic sample consists of 889 n... | 10.1016/j.whi.2009.02.001 | 19,447,320 | D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D033182:Intention; D008137:Longitudinal Studies; D008875:Middle Aged; D010414:Pennsylvania; D011247:Pregnancy; D055815:Young Adult | Women's health issues : official publication of the Jacobs Institute of Women's Health | 2,009 | |
Retropharyngeal hematoma mimicking angioedema after intravenous thrombolysis for acute ischemic stroke. | Tissue plasminogen activator (tPA) is a cornerstone treatment for acute ischemic stroke (AIS). Administration of tPA is not without risk, and can provoke life threatening adverse reactions. Retropharyngeal hematoma (RPH) following tPA administration has only been reported after tenecteplase (TNK) administration for ST ... | 10.1016/j.ajem.2023.03.016 | 36,948,989 | D006801:Humans; D000368:Aged; D010959:Tissue Plasminogen Activator; D005343:Fibrinolytic Agents; D000083242:Ischemic Stroke; D020521:Stroke; D015912:Thrombolytic Therapy; D016896:Treatment Outcome; D002545:Brain Ischemia | The American journal of emergency medicine | 2,023 | D010959:Tissue Plasminogen Activator; D005343:Fibrinolytic Agents |
Comparison of intermittent haemodialysis, prolonged intermittent renal replacement therapy and continuous renal replacement haemofiltration for lithium toxicity: a case report. | This case report compares three types of renal replacement therapy for acute severe lithium toxicity and is the first to use prolonged intermittent renal replacement therapy (PIRRT). A peak lithium level of 13.2mmol/L was recorded after a 51- year-old man attempted suicide. He was treated with intermittent haemodialysi... | 21,627,581 | D058186:Acute Kidney Injury; D005500:Follow-Up Studies; D006440:Hemofiltration; D006801:Humans; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D017582:Renal Replacement Therapy; D013406:Suicide, Attempted; D013997:Time Factors | Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine | 2,011 | D016651:Lithium Carbonate | |
Lipid composition of brown adipose tissue as related to nutrition during the neonatal period in hypotrophic rats. | Animals with intrauterine growth retardation (IUGR) were obtained by artery clamping of one uterine horn of the rat on day 17 of gestation. Body weight reduction was at least 30% as compared with the control animals that originated from the other horn. Brown adipose tissue (ISBAT), which plays a role in nonshivering th... | 10.1093/jn/105.8.982 | 1,142,016 | D002001:Adipose Tissue, Brown; D000367:Age Factors; D000818:Animals; D001835:Body Weight; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D005260:Female; D005333:Fetus; D006128:Growth; D007774:Lactation; D050356:Lipid Metabolism; D008055:Lipids; D008892:Milk; D009748:Nutrition Disorders; D009929:Organ Size; D010... | The Journal of nutrition | 1,975 | D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D008055:Lipids; D010743:Phospholipids |
[Proliferative activity, DNA synthesis and reproductive death of immediate and late progeny of irradiated cells]. | In experiments on HeLa cells a study was made of a change in the rate of DNA synthesis, proliferative activity and reproductive death of exposed cells and their descendants throughout a number of generations. The rate of DNA synthesis decreased in 4 postirradiation generations, and a maximum inhibition (by 50%) was reg... | 3,823,381 | D001345:Autoradiography; D002452:Cell Count; D002455:Cell Division; D002470:Cell Survival; D004247:DNA; D005720:Gamma Rays; D006367:HeLa Cells; D006801:Humans; D008433:Mathematics; D008954:Models, Biological; D013997:Time Factors | Radiobiologiia | 1,987 | D004247:DNA | |
Population pharmacokinetic model of PI-88, a heparanase inhibitor. | PURPOSE
The aim of this study was to investigate typical population pharmacokinetic (PK) parameters, potential covariates, and interindividual and residual variabilities of PI-88, a heparanase endoglycosidase enzyme inhibitor being developed for the treatment of cancer.
METHODS
A population PK model of PI-88 was deve... | 10.1007/s00280-009-1080-z | 19,633,850 | D000328:Adult; D000368:Aged; D000465:Algorithms; D019540:Area Under Curve; D004791:Enzyme Inhibitors; D005260:Female; D005966:Glucuronidase; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D008954:Models, Biological; D009369:Neoplasms; D009844:Oligosaccharides; D013997:Time Factors;... | Cancer chemotherapy and pharmacology | 2,010 | D004791:Enzyme Inhibitors; D009844:Oligosaccharides; C120158:phosphomannopentaose sulfate; C038253:heparanase; D005966:Glucuronidase |
Continuous Pore-Spanning Lipid Bilayers on Silicon Oxide-Coated Porous Substrates. | A number of techniques has been developed and analyzed in recent years to generate pore-spanning membranes (PSMs). While quite a number of methods rely on nanoporous substrates, only a few use micrometer-sized pores to be able to individually resolve suspending membranes by means of fluorescence microscopy. To be able ... | 10.1021/acs.langmuir.7b02727 | 29,148,811 | Langmuir : the ACS journal of surfaces and colloids | 2,017 | ||
Automatic patient positioning based on robot rotational workspace for extended reality. | PURPOSE
Understanding the properties and aspects of the robotic system is essential to a successful medical intervention, as different capabilities and limits characterize each. Robot positioning is a crucial step in the surgical setup that ensures proper reachability to the desired port locations and facilitates docki... | 10.1007/s11548-023-02967-2 | 37,296,352 | International journal of computer assisted radiology and surgery | 2,023 | ||
Overexpression of GLUT1 correlates with Kras mutations in lung carcinomas. | Glucose is the major source of energy for cells, and glucose transporter 1 (GLUT1) is the most common glucose transporter. GLUT1 has been found to be aberrantly expressed in several tumor types. From the results of the microarray and serial analysis of gene expression (SAGE), GLUT1 transcript expression was found to be... | 10.3892/mmr.2011.736 | 22,200,795 | D000230:Adenocarcinoma; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000483:Alleles; D002289:Carcinoma, Non-Small-Cell Lung; D066246:ErbB Receptors; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D051272:Glucose Transporter Type 1; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung ... | Molecular medicine reports | 2,012 | D051272:Glucose Transporter Type 1; C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D066246:ErbB Receptors; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins |
Insights about multi-targeting and synergistic neuromodulators in Ayurvedic herbs against epilepsy: integrated computational studies on drug-target and protein-protein interaction networks. | Epilepsy, that comprises a wide spectrum of neuronal disorders and accounts for about one percent of global disease burden affecting people of all age groups, is recognised as apasmara in the traditional medicinal system of Indian antiquity commonly known as Ayurveda. Towards exploring the molecular level complex regul... | 10.1038/s41598-019-46715-6 | 31,332,210 | D000927:Anticonvulsants; D000076722:Drug Development; D004357:Drug Synergism; D004827:Epilepsy; D029001:Herbal Medicine; D006801:Humans; D008515:Medicine, Ayurvedic; D018377:Neurotransmitter Agents; D008517:Phytotherapy; D060066:Protein Interaction Maps | Scientific reports | 2,019 | D000927:Anticonvulsants; D018377:Neurotransmitter Agents |
Biological Dose Optimization for Particle Arc Therapy Using Helium and Carbon Ions. | PURPOSE
To present biological dose optimization for particle arc therapy using helium and carbon ions.
METHODS AND MATERIALS
Treatment planning and optimization procedures were developed for spot-scanning hadron arc (SHArc) delivery using the RayStation treatment planning system and FRoG dose engine. The SHArc optimi... | 10.1016/j.ijrobp.2022.04.025 | 35,490,991 | D002244:Carbon; D006371:Helium; D006801:Humans; D007477:Ions; D008297:Male; D058958:Organs at Risk; D061766:Proton Therapy; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated | International journal of radiation oncology, biology, physics | 2,022 | D007477:Ions; D006371:Helium; D002244:Carbon |
Plasma lactate concentration as an indicator of plasma caffeine concentration in acute caffeine poisoning. | AIM
Severe caffeine poisoning is rare, but is associated with high mortality. Plasma caffeine concentration is one of the indications of treatment of caffeine poisoning; however, it is not easily measured at most emergency departments. If the plasma lactate concentration and the plasma caffeine concentration were corre... | 10.1002/ams2.28 | 29,930,840 | Acute medicine & surgery | 2,014 | ||
4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls β-Cell Mass. | The mammalian target of rapamycin complex 1 (mTORC1) regulates several biological processes, although the key downstream mechanisms responsible for these effects are poorly defined. Using mice with deletion of eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2), we determine that this downstream targ... | 10.2337/db15-1443 | 27,217,487 | D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002453:Cell Cycle; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D002470:Cell Survival; D039642:Eukaryotic Initiation Factors; D055504:Insulin Receptor Substrate Proteins; D050417:Insulin-Secreting Cells; D053614:Janus Kinase 2; D008297:Male; D0000... | Diabetes | 2,016 | D048868:Adaptor Proteins, Signal Transducing; C491255:Eif4ebp2 protein, mouse; D039642:Eukaryotic Initiation Factors; D055504:Insulin Receptor Substrate Proteins; D046912:Multiprotein Complexes; C115327:Sh2bpsm1 protein, mouse; D053614:Janus Kinase 2; D000076222:Mechanistic Target of Rapamycin Complex 1; D058570:TOR Se... |
A Wearable Testbed for Studying Variable Transmission in Body-Powered Prosthetic Gripping. | For those with upper limb absence, body-powered prostheses continue to be popular for many activities despite being an old technology; these devices can provide both inherent haptic feedback and mechanical robustness. Yet, they can also result in strain and fatigue. Body-powered prosthetic graspers typically consist of... | 10.1109/ICORR58425.2023.10304687 | 37,941,256 | D006801:Humans; D011474:Prosthesis Design; D006225:Hand; D001186:Artificial Limbs; D018737:Hand Strength; D000076251:Wearable Electronic Devices | IEEE ... International Conference on Rehabilitation Robotics : [proceedings] | 2,023 | |
Energy requirements. | The determination of the appropriate energy and nutritional requirements of a newborn infant requires a clear goal of the energy and other compounds to be administered, valid methods to measure energy balance and body composition, and knowledge of the neonatal metabolic capacities. Providing an appropriate amount of en... | 10.1016/j.siny.2006.10.008 | 17,161,032 | D004734:Energy Metabolism; D006801:Humans; D007225:Infant Food; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007234:Infant, Premature; D009751:Nutritional Requirements | Seminars in fetal & neonatal medicine | 2,007 | |
Rectal carcinoma during pregnancy. | Rectal carcinoma presenting during pregnancy is rare with a reported incidence of 0.002%. Management of such an emotionally charged condition can be difficult, especially when the twin goals of curing the disease and preserving the pregnancy are divergent. Four cases of rectal carcinoma presenting during pregnancy are ... | 10.1111/j.1445-2197.1994.tb02304.x | 8,085,977 | D000022:Abortion, Spontaneous; D000328:Adult; D005260:Female; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D012004:Rectal Neoplasms | The Australian and New Zealand journal of surgery | 1,994 | |
Glycoproteins of platelet membranes from Glanzmann's thrombasthenia. A comparison with normal using carbohydrate-specific or protein-specific labelling techniques and high-resolution two-dimensional gel electrophoresis. | Platelets from Glanzmann's thrombasthenia patients and from normal donor were surface labeled by techniques specific for sugars (terminal sialic acid, penultimate galactose/N-acetylgalactosamine) and proteins (tyrosine-histidine residues). These labelled platelets were solubilized in sodium dodecyl sulphate and separat... | 10.1111/j.1432-1033.1981.tb05346.x | 7,195,813 | D001791:Blood Platelet Disorders; D001792:Blood Platelets; D002462:Cell Membrane; D004591:Electrophoresis, Polyacrylamide Gel; D006023:Glycoproteins; D006801:Humans; D008565:Membrane Proteins; D012794:Sialic Acids; D009626:Terminology as Topic | European journal of biochemistry | 1,981 | D006023:Glycoproteins; D008565:Membrane Proteins; D012794:Sialic Acids |
Effect of oestrogen on fetal survival in the rabbit. | Pregnant rabbits (Day 18) were treated i.m. for 3 days with 10 microgram oestradiol 17beta/kg. The number of dead fetuses was significantly greater than in the control animals but corpus luteum weight and peripheral progesterone concentrations were not affected. Fetal death was therefore not due to luteolysis. | 10.1530/jrf.0.0530237 | 690,969 | D000818:Animals; D003338:Corpus Luteum; D004958:Estradiol; D005260:Female; D005328:Fetal Viability; D009929:Organ Size; D011247:Pregnancy; D011374:Progesterone; D011817:Rabbits | Journal of reproduction and fertility | 1,978 | D011374:Progesterone; D004958:Estradiol |
Effects of sodium fluoride on water and acid secretion, soluble mucus and adherent mucus of the rat stomach. | Chronic and acute ingestion of fluoride may lead to both structural and functional alterations of the gastric mucosa. The aim of this study was to investigate the effects of sodium fluoride on gastric secretion and mucosal barrier. Filling the rat stomach for 1 h with sodium fluoride (5 and 20 mmol/L) induced an increa... | 10.1155/2000/219623 | 10,888,729 | D000818:Animals; D001826:Body Fluids; D005260:Female; D005643:Fucose; D005690:Galactose; D005753:Gastric Mucosa; D006863:Hydrogen-Ion Concentration; D009093:Mucus; D051381:Rats; D017208:Rats, Wistar; D012969:Sodium Fluoride; D013270:Stomach | Canadian journal of gastroenterology = Journal canadien de gastroenterologie | 2,000 | D005643:Fucose; D012969:Sodium Fluoride; D005690:Galactose |
Caroli disease associated with vein of Galen malformation in a male child. | We report the first case of a male child with both Caroli disease and vein of Galen malformation. The neonate presented to our department with congestive heart failure as a result of the intracranial arteriovenous high-flow shunt. Over time, several endovascular embolizations led to a complete angiographic occlusion of... | 10.1542/peds.2013-0747 | 24,958,584 | D016767:Caroli Disease; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D054080:Vein of Galen Malformations | Pediatrics | 2,014 | |
Vertical distribution of microplastics in a river water column using an innovative sampling method. | Due to limitations of sampling methods, subsurface water is usually a less well-investigated compartment of the water column when scientists assess microplastic contamination. In this study, microplastic (MP) contamination was assessed in a freshwater river both in surface and subsurface using an innovative sampling me... | 10.1007/s10661-023-11915-1 | 37,828,146 | D000080545:Microplastics; D010969:Plastics; D045483:Rivers; D019015:Geologic Sediments; D014874:Water Pollutants, Chemical; D004784:Environmental Monitoring; D014867:Water | Environmental monitoring and assessment | 2,023 | D000080545:Microplastics; D010969:Plastics; D014874:Water Pollutants, Chemical; D014867:Water |
Nondestructive Prediction of Isoflavones and Oligosaccharides in Intact Soybean Seed Using Fourier Transform Near-Infrared (FT-NIR) and Fourier Transform Infrared (FT-IR) Spectroscopic Techniques. | The demand for rapid and nondestructive methods to determine chemical components in food and agricultural products is proliferating due to being beneficial for screening food quality. This research investigates the feasibility of Fourier transform near-infrared (FT-NIR) and Fourier transform infrared spectroscopy (FT-I... | 10.3390/foods11020232 | 35,053,964 | Foods (Basel, Switzerland) | 2,022 | ||
Unusual presentation of a third ventricular cyst in a patient with basal cell nevus syndrome. | Patients with basil cell nevus syndrome often have neurologic manifestations that occasionally cause complications. I report a case of a third ventricular cyst causing unusual symptoms in a 16-year-old boy. The discussion includes a review of the various neurologic signs and symptoms in this syndrome. | 10.1111/j.1525-1470.1994.tb00097.x | 7,899,182 | D000293:Adolescent; D001478:Basal Cell Nevus Syndrome; D001927:Brain Diseases; D001932:Brain Neoplasms; D002552:Cerebral Ventricles; D003560:Cysts; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D014696:Ventriculostomy | Pediatric dermatology | 1,994 | |
Different pattern of recovery of fast and slow muscles following nerve injury in the rat. | The sciatic nerve was crushed in 5-6-day-old rats and the time course of recovery and changes in physiological and morphological properties of reinnervated fast and slow muscles was compared. The maximal tetanic tension developed by the reinnervated muscles was recorded at different times from about 18 days of age, whe... | 10.1113/jphysiol.1984.sp015163 | 6,737,299 | D000818:Animals; D009119:Muscle Contraction; D009121:Muscle Denervation; D009126:Muscle Relaxation; D009132:Muscles; D009409:Nerve Crush; D009416:Nerve Regeneration; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D012584:Sciatic Nerve; D014034:Toes | The Journal of physiology | 1,984 | |
Diagnostic value of clinical examination and various imaging techniques for breast implant rupture as determined in 81 patients having implant removal. | To determine sensitivity and specificity of magnetic resonance imaging (MRI) and ultrasonography (US) in the detection of breast implant rupture, and also to determine the relative merits of clinical examination and mammography, we studied 81 patients (160 implants). All patients had implants removed, thus allowing con... | 10.1097/00007611-199604000-00009 | 8,614,880 | D000328:Adult; D018427:Breast Implants; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008875:Middle Aged; D011446:Prospective Studies; D011475:Prosthesis Failure; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D014463:Ultr... | Southern medical journal | 1,996 | |
Biomass and nutrient concentration of sweet corn roots and shoots under organic amendments application. | Two field experiments were conducted at the Waimanalo research station on the island of O'ahu, Hawaii to study the effect of chicken (CM) and dairy (DM) manures on biomass and nutrient concentration in sweet corn roots and shoots. Sweet corn (super sweet 10, Zea Mays L. subsp. mays) was grown for two consecutive growin... | 10.1080/03601230903163921 | 20,183,085 | D000818:Animals; D003612:Dairying; D006254:Hawaii; D008372:Manure; D018517:Plant Roots; D018520:Plant Shoots; D011200:Poultry; D012037:Refuse Disposal; D014131:Trace Elements; D003313:Zea mays | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes | 2,009 | D008372:Manure; D014131:Trace Elements |
Holiday travel: immunisation. | More people travel abroad each year, but they often receive conflicting advice about immunisation from travel agents, embassies, doctors and nurses. Published guidelines should be followed carefully to avoid risk of litigation. | 2,594,643 | D006293:Health Promotion; D006801:Humans; D007114:Immunization; D007603:Jurisprudence; D014195:Travel | The Practitioner | 1,989 | ||
Phytochemistry and pharmacology of Celastrus paniculatus Wild.: a nootropic drug. | OBJECTIVES
Celastrus paniculatus Wild is an evergreen climbing shrub. The plant is of great significance in the traditional Indian System of Medicine, such as Ayurveda, Unani, and Siddha. The seeds and their oil are extensively used to treat neurological disorders such as cognitive dysfunction, paralysis, epilepsy, ins... | 10.1515/jcim-2021-0251 | 34,529,902 | Journal of complementary & integrative medicine | 2,023 | ||
Open lung biopsy in diagnosing pulmonary infiltrates in immunosuppressed patients. | From July, 1973, to June, 1977, 25 patients in an immunosuppressed state from underlying reticuloendothelial neoplasm or associated chemotherapy, underwent open biopsy of the lung at the University of Maryland Hospital for diagnosis of unilateral diffuse pulmonary infiltrates. Eight patients were in marked respiratory ... | 10.1016/s0003-4975(10)63135-9 | 507,982 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents; D001706:Biopsy; D002648:Child; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D008168:Lung; D008171:Lung Diseases; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D009369:Neoplasms; D011658:Pulmonary Fibrosis | The Annals of thoracic surgery | 1,979 | D000970:Antineoplastic Agents |
Nano-sized Mn oxide/agglomerated silsesquioxane composite as a good catalyst for water oxidation. | Water splitting to hydrogen and oxygen is an important reaction to store sustainable energies, and water oxidation is identified as the bottleneck for water splitting because it requires the high activation energy to perform. Herein a nano-sized Mn oxide/agglomerated silsesquioxane composite was used to synthesize an e... | 10.1007/s11120-016-0225-2 | 26,846,654 | D002384:Catalysis; D017895:Manganese Compounds; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles; D017646:Organosilicon Compounds; D010084:Oxidation-Reduction; D010087:Oxides; D010788:Photosynthesis; D017550:Spectroscopy, Fourier Transform Infrared; D014867:Water | Photosynthesis research | 2,016 | C512088:1,3-bis(1,1,3,3,5,5-hexaethoxy-1,3,5-trisilacyclohexyl)propane; D017895:Manganese Compounds; D017646:Organosilicon Compounds; D010087:Oxides; D014867:Water; C027424:manganese oxide |
Immunohistochemistry to Study YAP in Human Tissue Samples. | Immunohistochemistry (IHC) analysis of YAP in human tissue samples represents an important means to analyze overall expression levels and subcellular localization of YAP in specimen of interest. As transcriptional coactivator, alterations of YAP levels in the cellular nucleus allow important predictions for YAP activit... | 10.1007/978-1-4939-8910-2_7 | 30,565,127 | D015415:Biomarkers; D018797:Cell Cycle Proteins; D002467:Cell Nucleus; D000078332:Data Analysis; D000090683:Hippo Signaling Pathway; D006801:Humans; D007150:Immunohistochemistry; D008853:Microscopy; D009687:Nuclear Proteins; D017346:Protein Serine-Threonine Kinases; D015398:Signal Transduction; D014157:Transcription Fa... | Methods in molecular biology (Clifton, N.J.) | 2,019 | D015415:Biomarkers; D018797:Cell Cycle Proteins; D009687:Nuclear Proteins; D014157:Transcription Factors; C456659:YY1AP1 protein, human; D017346:Protein Serine-Threonine Kinases |
Preparation and characterization of indomethacin magnetic nanoparticles. | Nanoparticles of polymethylmethacrylate were prepared by the emulsion polymerization technique. The drug was embedded in the nanoparticles. The controlled growth of ferric hydroxide particles in the presence of non-ionic surfactant was effected to obtain nano-size particles and these were subsequently heated to obtain ... | 10.3109/02652048809064169 | 3,199,309 | D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena; D004655:Emulsions; D052203:Ferrosoferric Oxide; D007213:Indomethacin; D007501:Iron; D008854:Microscopy, Electron; D010087:Oxides; D010316:Particle Size; D011108:Polymers | Journal of microencapsulation | 1,988 | D004655:Emulsions; D010087:Oxides; D011108:Polymers; D007501:Iron; D052203:Ferrosoferric Oxide; D007213:Indomethacin |
Prediction of pregnancy in IVF cycles on the fourth day of ovarian stimulation. | PURPOSE
Prediction of IVF outcome on the first days of ovarian stimulation has focused clinical research for many years. The aim of this work is to predict the probability of pregnancy on the fourth day of ovarian stimulation for IVF cycle, using parameters usually determined in this stage--estradiol, antral follicle c... | 10.1007/s10815-007-9144-7 | 17,597,392 | D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female; D010062:Ovulation Induction; D011247:Pregnancy; D011258:Pregnancy Tests; D011379:Prognosis; D012372:ROC Curve; D012680:Sensitivity and Specificity; D013997:Time Factors; D016896:Treatment Outcome | Journal of assisted reproduction and genetics | 2,007 | |
Generation of iPS Cells from Human Peripheral Blood Mononuclear Cells Using Episomal Vectors. | Peripheral blood is the easy-to-access, minimally invasive, and the most abundant cell source to use for cell reprogramming. The episomal vector is among the best approaches for generating integration-free induced pluripotent stem (iPS) cells due to its simplicity and affordability. Here we describe the detailed protoc... | 10.1007/7651_2014_139 | 25,403,468 | D018929:Cell Culture Techniques; D002454:Cell Differentiation; D002478:Cells, Cultured; D065150:Cellular Reprogramming; D015870:Gene Expression; D005822:Genetic Vectors; D017919:Hepatitis B Virus, Woodchuck; D006801:Humans; D057026:Induced Pluripotent Stem Cells; D007963:Leukocytes, Mononuclear; D010957:Plasmids; D0114... | Methods in molecular biology (Clifton, N.J.) | 2,016 | C494811:BCL2L1 protein, human; D011994:Recombinant Proteins; D051020:bcl-X Protein |
Cucurbitacin D Induces G2/M Phase Arrest and Apoptosis via the ROS/p38 Pathway in Capan-1 Pancreatic Cancer Cell Line. | Pancreatic cancer has a poor prognosis with a five-year survival rate of less than 10%. Moreover, chemotherapy is mostly rendered ineffective owing to chemotherapy resistance and cytotoxicity. Therefore, the development of effective therapeutic strategies and novel drugs against pancreatic cancer is an urgent need. Cuc... | 10.1155/2020/6571674 | 33,029,168 | Evidence-based complementary and alternative medicine : eCAM | 2,020 | ||
A new vector derived from Agrobacterium rhizogenes plasmids: a micro-Ri plasmid and its use to construct a mini-Ri plasmid. | A new binary vector system has been constructed, based on agropine-type root-inducing plasmid (pRi) left transferred-region border sequences cloned in a plasmid containing the replication origin of another A. rhizogenes plasmid (pArA4a). This micro-pRi has been used to introduce a chimeric kanamycin resistance gene int... | 10.1016/0378-1119(87)90253-8 | 3,623,102 | D003001:Cloning, Molecular; D005822:Genetic Vectors; D010944:Plants; D010957:Plasmids; D012093:Replicon; D012231:Rhizobium; D012641:Selection, Genetic | Gene | 1,987 | |
Piscivorous cyprinid fish modulates suction feeding kinematics to capture elusive prey. | Previous studies have shown that evasive prey generally elicit a different kinematical pattern of prey capture from suction feeding fish compared to non-evasive types of prey. However, no evidence exists that predatory fish can modulate their prey capture kinematics in response to whether or not an elusive prey perform... | 10.1016/j.zool.2010.10.001 | 21,185,704 | D000818:Animals; D003530:Cyprinidae; D005247:Feeding Behavior; D011235:Predatory Behavior | Zoology (Jena, Germany) | 2,011 | |
Enteral nutrition as treatment option for Crohn's disease: in kids only? | Inflammatory bowel disorders (IBD) are characterized by chronic and recurrent inflammatory reactions of the intestinal mucosa resulting in progressing ulcerating lesions. Research over the past decade clearly identified in patients with Crohn's disease (CD) a marked dysregulation of the intestinal microbiome (dysbiosis... | 10.1159/000360716 | 25,227,299 | D000328:Adult; D002648:Child; D003424:Crohn Disease; D004750:Enteral Nutrition; D006801:Humans; D015201:Meta-Analysis as Topic; D016032:Randomized Controlled Trials as Topic; D012074:Remission Induction; D016896:Treatment Outcome | Nestle Nutrition Institute workshop series | 2,014 | |
Distinct cognitive control mechanisms as revealed by modality-specific conflict adaptation effects. | Cognitive control is essential to resolve conflict in stimulus-response compatibility (SRC) tasks. The SRC effect in the current trial is reduced after an incongruent trial as compared with a congruent trial, a phenomenon being termed conflict adaptation (CA). The CA effect is found to be domain-specific, such that it ... | 10.1037/xhp0000351 | 28,345,947 | D000222:Adaptation, Physiological; D000293:Adolescent; D000328:Adult; D003220:Conflict, Psychological; D056344:Executive Function; D005260:Female; D006801:Humans; D008297:Male; D010364:Pattern Recognition, Visual; D011932:Reading; D013067:Speech Perception; D055815:Young Adult | Journal of experimental psychology. Human perception and performance | 2,017 | |
Bioaccessibility of BDE 47 in a simulated gastrointestinal system and its metabolic transformation mechanisms in Caco-2 cells. | Polybrominated diphenyl ethers (PBDEs) have been regarded as ubiquitous environmental pollutants. However, the absorption and transformation of these compounds after ingestion are not well understood yet. In this study, the bioaccessibility and metabolic pathway of 2,2',4,4'- tetrabromodiphenyl ether (BDE47) was invest... | 10.1016/j.chemosphere.2018.09.008 | 30,268,896 | D001682:Biological Availability; D018938:Caco-2 Cells; D041981:Gastrointestinal Tract; D055768:Halogenated Diphenyl Ethers; D006801:Humans; D012989:Soil Pollutants; D014018:Tissue Distribution | Chemosphere | 2,019 | D055768:Halogenated Diphenyl Ethers; D012989:Soil Pollutants; C511295:2,2',4,4'-tetrabromodiphenyl ether |
Computer-assisted reporting system for the follow-up of patients with prosthetic heart valves. | The implantation of large numbers of prosthetic heart valves carries with it the responsibility for continual reassessment of all aspects of patient management. Experience with more than 2,000 prosthetic valve operations since 1963 led to the development of a comprehensive computer-assisted data collection, management ... | 10.1016/0002-9149(78)90939-6 | 685,854 | D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D006801:Humans; D008499:Medical Records; D009862:Online Systems | The American journal of cardiology | 1,978 | |
Very early onset of an acute myeloid leukemia in an adult patient with B-cell lymphoblastic leukemia. | We report on a case of a 30-year-old male with acute B-lymphoblastic leukemia (B-ALL) with immunophenotype CD19(+), CD22(+), CD20(+), CD10(+), with aberrant expression of CD13 and CD117, and IgH gene rearrangements. Three months after treatment with GMALL-2003 and Ida/FLAG protocols bone marrow showed predominance of b... | 10.1111/j.1751-553X.2007.00968.x | 19,143,872 | D000328:Adult; D017809:Fatal Outcome; D015322:Gene Rearrangement, B-Lymphocyte; D005803:Genes, Immunoglobulin; D006801:Humans; D015448:Leukemia, B-Cell; D015470:Leukemia, Myeloid, Acute; D008297:Male | International journal of laboratory hematology | 2,009 | |
Local anesthesia for prostate biopsy by periprostatic lidocaine injection: a double-blind placebo controlled study. | PURPOSE
We determined the efficacy of anesthesia for prostate biopsy by periprostatic lidocaine injection.
MATERIALS AND METHODS
A total of 90 consecutive patients undergoing prostate biopsies were randomized into lidocaine and placebo groups of 45 each in double-blind fashion. A 5 ml. dose of 1% lidocaine or 0.9% so... | 10.1016/S0022-5347(01)69086-4 | 11,792,919 | D000368:Aged; D000369:Aged, 80 and over; D000772:Anesthesia, Local; D000779:Anesthetics, Local; D001707:Biopsy, Needle; D004311:Double-Blind Method; D006801:Humans; D008012:Lidocaine; D008297:Male; D008875:Middle Aged; D010149:Pain, Postoperative; D017060:Patient Satisfaction; D011467:Prostate | The Journal of urology | 2,002 | D000779:Anesthetics, Local; D008012:Lidocaine |
Investigation of the In-Vivo Cytotoxicity and the In Silico-Prediction of MDM2-p53 Inhibitor Potential of Euphorbia peplus Methanolic Extract in Rats. | This study explored the probable in vivo cardiac and renal toxicities together with in silico approaches for predicting the apoptogenic potential of Euphorbia peplus methanolic extract (EPME) in rats. Cardiac and renal injury biomarkers were estimated with histopathological and immunohistochemical evaluations of both k... | 10.3390/toxins11110642 | 31,689,934 | D000818:Animals; D017209:Apoptosis; D015415:Biomarkers; D002470:Cell Survival; D003198:Computer Simulation; D028481:Euphorbia; D006321:Heart; D007668:Kidney; D008297:Male; D062105:Molecular Docking Simulation; D009206:Myocardium; D010936:Plant Extracts; D051736:Proto-Oncogene Proteins c-mdm2; D051381:Rats; D017208:Rats... | Toxins | 2,019 | D015415:Biomarkers; D010936:Plant Extracts; D016159:Tumor Suppressor Protein p53; C497208:Mdm2 protein, rat; D051736:Proto-Oncogene Proteins c-mdm2 |
Cholesterol oxidase: sources, physical properties and analytical applications. | Since Flegg (H.M. Flegg, An investigation of the determination of serum cholesterol by an enzymatic method, Ann. Clin. Biochem. 10 (1973) 79-84) and Richmond (W. Richmond, The development of an enzymatic technique for the assay of cholesterol in biological fluids, Scand. J. clin. Lab. Invest. 29 (1972) 25; W. Richmond,... | 10.1016/s0960-0760(00)00044-3 | 10,822,008 | D001951:Brevibacterium; D002784:Cholesterol; D002789:Cholesterol Oxidase; D004912:Erythrocytes; D006801:Humans; D008074:Lipoproteins; D009615:Nocardia; D011487:Protein Conformation; D011549:Pseudomonas; D012240:Rhodococcus; D013256:Steroids; D013302:Streptomyces; D013379:Substrate Specificity | The Journal of steroid biochemistry and molecular biology | 2,000 | D008074:Lipoproteins; D013256:Steroids; D002784:Cholesterol; D002789:Cholesterol Oxidase |
Lower-Limb Motor Assessment With Corticomuscular Coherence of Multiple Muscles During Ankle Dorsiflexion After Stroke. | Motor impairment after stroke is generally caused by damage to the neural networks that control movement. Corticomuscular coherence (CMC) is a valid method to analyze the functional connectivity of the corticospinal pathway between the cerebral cortex and muscles. However, current studies on CMC in stroke patients only... | 10.1109/TNSRE.2022.3217571 | 36,288,216 | D006801:Humans; D000842:Ankle; D018482:Muscle, Skeletal; D004576:Electromyography; D020521:Stroke; D004569:Electroencephalography | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society | 2,023 | |
Antifungal activity of colistin against mucorales species in vitro and in a murine model of Rhizopus oryzae pulmonary infection. | In immunosuppressed hosts, mucormycosis is a life-threatening infection with few treatment options. We studied the activity of colistin (polymyxin E) against Mucorales species in vitro and in a murine model of pulmonary Rhizopus oryzae infection. Colistin exhibited fungicidal activity in vitro against Mucorales spores ... | 10.1128/AAC.00956-09 | 19,858,263 | D000255:Adenosine Triphosphate; D000818:Animals; D000935:Antifungal Agents; D003091:Colistin; D003593:Cytoplasm; D005260:Female; D025301:Hyphae; D008168:Lung; D008172:Lung Diseases, Fungal; D051379:Mice; D008807:Mice, Inbred BALB C; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D00909... | Antimicrobial agents and chemotherapy | 2,010 | D000935:Antifungal Agents; D013778:Tetrazolium Salts; C059087:2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazolium hydroxide; D000255:Adenosine Triphosphate; D003091:Colistin |
Association between estrogen receptor gene polymorphism and back pain intensity in female patients with degenerative lumbar spondylolisthesis. | STUDY DESIGN
Prospective study.
OBJECTIVE
To examine the possible association of estrogen receptor α (ERα) polymorphisms and pain intensity in symptomatic female degenerative spondylolisthesis (DS) patients.
SUMMARY OF BACKGROUND DATA
DS has been associated with a significant sex effect. Thus, several studies about... | 10.1097/BSD.0b013e318260a09c | 22,668,753 | D000368:Aged; D001416:Back Pain; D047628:Estrogen Receptor alpha; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae; D008875:Middle Aged; D010147:Pain Measurement; D011110:Polymorphism, Genetic; D011446:Prospective Studies; D013168:Spondylolisthesis | Journal of spinal disorders & techniques | 2,013 | C506487:ESR1 protein, human; D047628:Estrogen Receptor alpha |
Contrast media for cardiothoracic MR imaging. | Contrast media have been used for the study of disease of the thorax. Most experience has consisted of the use of MR contrast media for improving the delineation of acute myocardial infarction, for demarcating the area of acute myocardial ischemia, and for demonstrating the area of potentially jeopardized myocardium af... | 10.1002/jmri.1880030138 | 8,428,094 | D000818:Animals; D001808:Blood Vessels; D003287:Contrast Media; D004419:Dysprosium; D005682:Gadolinium; D006084:Graft Rejection; D006331:Heart Diseases; D016027:Heart Transplantation; D006801:Humans; D007089:Image Enhancement; D008171:Lung Diseases; D008279:Magnetic Resonance Imaging; D008477:Mediastinal Diseases; D009... | Journal of magnetic resonance imaging : JMRI | 1,993 | D003287:Contrast Media; D004419:Dysprosium; D005682:Gadolinium |
Spleen size: how well do linear ultrasound measurements correlate with three-dimensional CT volume assessments? | Ultrasound measurement of splenic length is standard practice, but it is not known how well this represents the true size of the spleen. Previous studies, using a combination of measurements from in vivo and resected spleens, were subject to error because of changes in splenic size. The aim of this study was to correla... | 10.1259/bjr.75.895.750573 | 12,145,129 | D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D011856:Radiographic Image Enhancement; D012680:Sensitivity and Specificity; D013154:Spleen; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography | The British journal of radiology | 2,002 | |
Release of copper from embedded solid copper bullets into muscle and fat tissues of fallow deer (Dama dama), roe deer (Capreolus capreolus), and wild boar (Sus scrofa) and effect of copper content on oxidative stability of heat-processed meat. | When venison with embedded copper bullets was subjected to different culinary processing procedures, the amount of copper released from the embedded bullet was affected more by the retention period of the bullet in the meat during cool storage, than by the different heating protocols. The presence of copper fragments h... | 26,005,913 | D000273:Adipose Tissue; D000818:Animals; D003300:Copper; D003670:Deer; D004305:Dose-Response Relationship, Drug; D005511:Food Handling; D006358:Hot Temperature; D018482:Muscle, Skeletal; D018384:Oxidative Stress; D000069466:Red Meat; D034421:Sus scrofa; D017392:Thiobarbituric Acid Reactive Substances | Meat science | 2,015 | D017392:Thiobarbituric Acid Reactive Substances; D003300:Copper | |
Dynamic Reference Selection-Based Self-Localization Algorithm for Drifted Underwater Acoustic Networks. | Self-localization has become one of the major areas of research in drifted underwater acoustic networks (DUANs) since many applications are based on the knowledge of nodes' positions. However, self-localization for DUANs faces two main challenges: the insufficient anchors and the varying network topology. Both affect t... | 10.3390/s19183920 | 31,514,414 | Sensors (Basel, Switzerland) | 2,019 | ||
Time-efficiency and cost-analysis comparing three digital workflows for treatment with monolithic zirconia implant fixed dental prostheses: A double-blinded RCT. | OBJECTIVES
This double-blinded randomized controlled trial investigated economic performance indicators (EPI) in terms of time-efficiency and production costs of 3-unit monolithic zirconium-dioxide (ZrO2) implant fixed dental prostheses (iFDP) in three different workflows.
METHODS
Twenty patients with two Straumann T... | 10.1016/j.jdent.2021.103779 | 34,391,875 | D017076:Computer-Aided Design; D003442:Crowns; D003761:Dental Impression Technique; D017267:Dental Prosthesis Design; D006801:Humans; D057188:Workflow; D015040:Zirconium | Journal of dentistry | 2,021 | D015040:Zirconium; C028541:zirconium oxide |
Real-world experience with cabazitaxel in patients with metastatic castration-resistant prostate cancer: a final, pooled analysis of the compassionate use programme and early access programme. | BACKGROUND
Cabazitaxel is a second-generation taxane approved for use in patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with docetaxel. Early access programmes were established to allow eligible patients with mCRPC access to cabazitaxel before regulatory approval.
MATERIALS A... | 10.18632/oncotarget.27031 | 31,289,614 | Oncotarget | 2,019 | ||
SUBACUTE THYROIDITIS IN A CHILD. | OBJECTIVE
The objective of this report is to describe the presentation, disease course, and management of subacute thyroiditis (SAT) in children. SAT is a rare cause of thyroiditis in children and can be mistaken for acute suppurative thyroiditis, which may be more common in pediatrics.
METHODS
We present a 7-year-ol... | 10.4158/ACCR-2018-0211 | 31,967,030 | AACE clinical case reports | 2,019 | ||
Comparison of nebulised salbutamol and ipratropium bromide with salbutamol alone in the treatment of chronic obstructive pulmonary disease. | BACKGROUND
Patients admitted with acute exacerbation of chronic obstructive pulmonary disease (COPD) are often prescribed ipratropium bromide in combination with a beta 2 agonist such as salbutamol. Studies have not shown any benefit in adding ipratropium bromide to salbutamol in acute exacerbations of COPD, but these ... | 10.1136/thx.50.8.834 | 7,570,433 | D000280:Administration, Inhalation; D000368:Aged; D000420:Albuterol; D004338:Drug Combinations; D005541:Forced Expiratory Volume; D006801:Humans; D009241:Ipratropium; D008173:Lung Diseases, Obstructive; D014797:Vital Capacity | Thorax | 1,995 | D004338:Drug Combinations; D009241:Ipratropium; D000420:Albuterol |
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