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[Transscleral magnetic fixation of the retina in complicated retinal detachment. A preliminary report of our experiences]. | The authors describe a new technique for transscleral fixation of a detached retina. A small metal pin is brought into contact with the surface of the retina and is held in position by an extraocular magnet. This technique has been used successfully on three patients with giant tears and with large retinotomies as a pr... | 10.1055/s-2008-1054620 | 6,513,404 | D006801:Humans; D008280:Magnetics; D008866:Microsurgery; D012163:Retinal Detachment; D012167:Retinal Perforations; D012591:Scleral Buckling; D014821:Vitrectomy | Klinische Monatsblatter fur Augenheilkunde | 1,984 | |
Platinum concentrations in human glioblastoma multiforme following the use of cisplatin. | A 24-year-old female with glioblastoma multiforme was not given a nitrosourea because of interstitial lung disease. Cisplatin was administered monthly for five cycles until disease progression. A second debulking procedure was performed and tumor tissue assayed for the presence of platinum. Levels were measurable 7 wee... | 6,286,121 | D000328:Adult; D001812:Blood-Brain Barrier; D001932:Brain Neoplasms; D002945:Cisplatin; D005260:Female; D005909:Glioblastoma; D006801:Humans; D011658:Pulmonary Fibrosis; D014018:Tissue Distribution | Cancer treatment reports | 1,982 | D002945:Cisplatin | |
[Comparison of the effects of 2 anesthesiologic technics on hemostasis]. | Results of hemocoagulation test in anesthesia performed upon 17 patients treated with Ethrane and 17 treated with NLA are reported in this paper. Normotest, Thrombotest and PTT are within normal limits. The two groups studied, however, showed a drop in the percentages of the Normotest and Thrombotest and a reduced PTT.... | 6,680,007 | D000328:Adult; D000368:Aged; D000777:Anesthetics; D001780:Blood Coagulation Tests; D004329:Droperidol; D005260:Female; D005283:Fentanyl; D006487:Hemostasis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011410:Propanidid; D013874:Thiopental | Annali dell'Ospedale Maria Vittoria di Torino | 1,983 | D000777:Anesthetics; D011410:Propanidid; D013874:Thiopental; D004329:Droperidol; D005283:Fentanyl | |
The contribution of perceived control of stressful life events and thought suppression to the symptoms of obsessive-compulsive disorder in both non-clinical and clinical samples. | The two studies presented in this paper investigated the impact of controllable versus uncontrollable stressful life events (SLE) and low versus high thought suppression upon symptoms of obsessive-compulsive disorder (OCD) in both a non-clinical sample (Study 1) and a clinical sample (Study 2). The sample for Study 1 c... | 10.1016/s0887-6185(02)00224-4 | 12,826,088 | D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders; D001315:Australia; D003192:Compulsive Behavior; D006801:Humans; D008297:Male; D008875:Middle Aged; D009770:Obsessive Behavior; D009771:Obsessive-Compulsive Disorder; D011569:Psychiatric Status Rating Scales; D011581:Psychological Tests; D012094:Repression, P... | Journal of anxiety disorders | 2,003 | |
Inflammatory infiltrate in skeletal muscle injected with Bothrops asper venom. | The time-course and composition of inflammatory infiltrate in mouse gastrocnemius injected with Bothrops asper venom was studied. The venom induced myonecrosis, and a prominent decrease in muscle levels of creatine kinase (CK) as early as 3 hr after envenomation. Inflammatory infiltrate was scarce by 6 hr. but increase... | 3,423,335 | D000818:Animals; D003402:Creatine Kinase; D003435:Crotalid Venoms; D004591:Electrophoresis, Polyacrylamide Gel; D051379:Mice; D009124:Muscle Proteins; D009132:Muscles; D009220:Myositis; D009336:Necrosis | Revista de biologia tropical | 1,986 | D003435:Crotalid Venoms; D009124:Muscle Proteins; D003402:Creatine Kinase | |
Genetic differences and heritability of antibody response to Escherichia coli vaccination in young broiler chicks. | Broiler chicken lines, selected divergently for high (HC) or low (LC) antibody titer to Escherichia coli vaccination at an early age, were evaluated for antibody response at the S5 and S9 generations of selection. The full-pedigreed populations consisted of about 300 and 400 chicks per line in S5 and S9, respectively. ... | 10.3382/ps.0750683 | 8,737,830 | D000367:Age Factors; D000704:Analysis of Variance; D000818:Animals; D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D002645:Chickens; D004926:Escherichia coli; D012641:Selection, Genetic | Poultry science | 1,996 | D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines |
Factors associated with cirrhosis development in chronic hepatitis C patients from an area of low prevalence. | The aim of this study was to evaluate the importance of different endogenous and exogenous factors associated with cirrhosis development among hepatitis C virus (HCV)-positive individuals from an area of low prevalence. We studied 106 consecutive HCV RNA positive patients who had undergone liver biopsy. Each patient wa... | 10.1046/j.1365-2893.1998.00082.x | 9,493,516 | D000328:Adult; D000367:Age Factors; D000368:Aged; D000428:Alcohol Drinking; D000437:Alcoholism; D001706:Biopsy; D018450:Disease Progression; D004641:Emigration and Immigration; D005260:Female; D016174:Hepacivirus; D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D019698:Hepatitis C, Chronic; D006801:H... | Journal of viral hepatitis | 1,998 | D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D012367:RNA, Viral; D000514:alpha 1-Antichymotrypsin; D000515:alpha 1-Antitrypsin |
Certain metals trigger fibrillation of methionine-oxidized alpha-synuclein. | The aggregation and fibrillation of alpha-synuclein has been implicated as a key step in the etiology of Parkinson's disease and several other neurodegenerative disorders. In addition, oxidative stress and certain environmental factors, including metals, are believed to play an important role in Parkinson's disease. Pr... | 10.1074/jbc.M303302200 | 12,754,258 | D002942:Circular Dichroism; D004926:Escherichia coli; D006801:Humans; D006861:Hydrogen Peroxide; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008027:Light; D008670:Metals; D008854:Microscopy, Electron; D009419:Nerve Tissue Proteins; D018384:Oxidative Stress; D010100:Oxygen; D011487:Protein Conformation; D0125... | The Journal of biological chemistry | 2,003 | D008670:Metals; D009419:Nerve Tissue Proteins; C497604:SNCA protein, human; D051843:Synucleins; D051844:alpha-Synuclein; D006861:Hydrogen Peroxide; D010100:Oxygen |
Differences in the oral size illusions produced by cross-modality matching of peg and hole stimuli by the tongue and fingers in humans. | Individuals overestimate the diameter of 1-mm-deep stimulus holes presented to the tongue when they use their fingers to select a hole of matching diameter. The aim here was to determine whether the oral size illusion evident for 1-mm-deep holes would also occur with 1-mm-high pegs of similar diameters. The illusion wa... | 10.1016/s0003-9969(00)00118-7 | 11,165,566 | D000328:Adult; D016001:Confidence Intervals; D005260:Female; D005385:Fingers; D006801:Humans; D007088:Illusions; D008297:Male; D008875:Middle Aged; D013236:Stereognosis; D014059:Tongue; D014110:Touch | Archives of oral biology | 2,001 | |
The C-terminal (331-376) sequence of Escherichia coli DnaJ is essential for dimerization and chaperone activity: a small angle X-ray scattering study in solution. | DnaJ, an Escherichia coli Hsp40 protein composed of 376 amino acid residues, is a chaperone with thioldisulfide oxidoreductase activity. We present here for the first time a small angle x-ray scattering study of intact DnaJ and a truncated version, DnaJ (1-330), in solution. The molecular weight of DnaJ and DnaJ (1-330... | 10.1074/jbc.M503643200 | 15,849,180 | D002845:Chromatography; D019281:Dimerization; D004220:Disulfides; D004305:Dose-Response Relationship, Drug; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli; D029968:Escherichia coli Proteins; D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins; D007700:Kinetics; D008958:Models, Molecula... | The Journal of biological chemistry | 2,005 | D004220:Disulfides; C494635:DnaJ protein, E coli; D029968:Escherichia coli Proteins; D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins; D018832:Molecular Chaperones; D013438:Sulfhydryl Compounds; D010088:Oxidoreductases |
Circulating DNA and lung cancer. | Lung cancer is the leading cause of cancer death worldwide. The majority of patients is diagnosed too late for curative treatment. There is an urgent need for a noninvasive test to identify early lung cancer. Although levels of circulating cell-free DNA in plasma or serum are higher in patients with lung cancer than in... | 10.1196/annals.1368.021 | 17,108,206 | D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm; D044127:Epigenesis, Genetic; D005819:Genetic Markers; D006801:Humans; D019656:Loss of Heterozygosity; D008175:Lung Neoplasms; D018895:Microsatellite Repeats; D009154:Mutation; D009857:Oncogenes | Annals of the New York Academy of Sciences | 2,006 | D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm; D005819:Genetic Markers |
The physicochemical and environmental factors affecting the distribution of Anopheles merus along the Kenyan coast. | BACKGROUND
Members of the Anopheles gambiae complex are the main transmitters of malaria. Anopheles merus is a member of the complex found along the Kenyan coast because it breeds in saline waters. An entomological study was conducted in Garithe Malindi District, to investigate the physicochemical and environmental fac... | 10.1186/s13071-015-0819-0 | 25,889,775 | D000818:Animals; D000852:Anopheles; D055598:Chemical Phenomena; D004275:DNA, Ribosomal; D017753:Ecosystem; D004772:Entomology; D004777:Environment; D016133:Polymerase Chain Reaction | Parasites & vectors | 2,015 | D004275:DNA, Ribosomal |
The risk less known: female-to-male transgender persons' vulnerability to HIV infection. | Studies have consistently found high levels of HIV infection among male-to-female (MTF) transgender people, particularly MTF sex workers. Due to lack of empirical data, HIV/AIDS risk among female-to-male (FTM) transgender people, however, is not well understood. This study analysed data from two needs assessment survey... | 10.1080/19540120512331325680 | 15,763,714 | D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005783:Gender Identity; D015658:HIV Infections; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D015143:Philadelphia; D012307:Risk Factors; D012309:Risk-Taking; D012725:Sexual Behavior; D014189:Transsexua... | AIDS care | 2,005 | |
Cerebral infarction and in-hospital mortality for patients admitted to hospital with intracardiac thrombus: insights from the National Inpatient Sample. | The factors associated with cerebral infarction and mortality in patients hospitalized with intracardiac thrombus are unknown. A retrospective cohort study was undertaken of nationally representative hospital admissions in the National Inpatient Sample with a diagnosis of intracardiac thrombus between 2016 to 2019. Mul... | 10.1007/s11239-023-02824-8 | 37,277,607 | D006801:Humans; D007297:Inpatients; D012189:Retrospective Studies; D017052:Hospital Mortality; D009404:Nephrotic Syndrome; D054556:Venous Thromboembolism; D013927:Thrombosis; D009203:Myocardial Infarction; D006331:Heart Diseases; D006761:Hospitals; D002544:Cerebral Infarction; D020521:Stroke; D019851:Thrombophilia; D01... | Journal of thrombosis and thrombolysis | 2,023 | |
Prediction of Incident Delirium Using a Random Forest classifier. | Delirium is a serious medical complication associated with poor outcomes. Given the complexity of the syndrome, prevention and early detection are critical in mitigating its effects. We used Confusion Assessment Method (CAM) screening and Electronic Health Record (EHR) data for 64,038 inpatient visits to train and test... | 10.1007/s10916-018-1109-0 | 30,430,256 | D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D003661:Decision Support Techniques; D003693:Delirium; D057286:Electronic Health Records; D005260:Female; D006760:Hospitalization; D006801:Humans; D016015:Logistic Models; D000069550:Machine Learning; D008297:Male; D008875:Middle Aged; D011237:Predictive Valu... | Journal of medical systems | 2,018 | |
Delivered oxygen fraction during simulated cardiopulmonary resuscitation depending on the kind of resuscitation bag and oxygen flow. | Emergency cases for resuscitation include built-in oxygen cylinders with limited oxygen supply. The use of a bag-valve mask device (BVMD) with a reservoir requires a high constant flow of oxygen to maintain a high concentration of delivered oxygen. The goal of the study was to analyze what fraction of inspired oxygen (... | 10.1097/MEJ.0b013e32834dd360 | 22,044,931 | D001944:Breath Tests; D004867:Equipment Design; D006801:Humans; D008397:Masks; D008422:Materials Testing; D010100:Oxygen; D010102:Oxygen Inhalation Therapy; D012121:Respiration, Artificial; D012129:Respiratory Function Tests; D015656:Respiratory Mechanics | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | 2,012 | D010100:Oxygen |
Non-traumatic spontaneous ileal perforation: experience with 125 cases. | BACKGROUND
Non-traumatic ileal perforation is a common cause of obscure peritonitis in developing and underdeveloped world. The perforation of the ileum is one of the causes of peritonitis that is difficult to diagnose preoperatively. The objective of the study was to determine the increasing frequency of cases of non-... | 25,672,180 | D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007077:Ileal Diseases; D007416:Intestinal Perforation; D008297:Male; D000267:Tissue Adhesions; D014385:Tuberculosis, Gastrointestinal; D014435:Typhoid Fever; D055815:Young Adult | Journal of Ayub Medical College, Abbottabad : JAMC | 2,014 | ||
Transurethral seminal vesiculoscopy for intractable hematospermia: experience from 144 patients. | PURPOSE
to describe the methodology of transurethral seminal vesiculoscopy and the anatomy of the area of the verumontanum, and to determine the safety of this procedure, especially in terms of postoperative complications.
METHODS
This retrospective observational study enrolled 144 patients with intractable hematospe... | 10.1186/s12894-021-00817-4 | 33,773,582 | D000328:Adult; D004724:Endoscopy; D051516:Hemospermia; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012669:Seminal Vesicles; D013521:Urologic Surgical Procedures, Male | BMC urology | 2,021 | |
[Calculi: interventional treatment]. | Extracorporeal shock wave lithotripsy is actually the most popular treatment in the urolithiasis. However, different factors influence the choice of the best treatment. Great progresses appeared in the conception of performing endoscopic material which led to minimize morbidity. Percutaneous approach is very popular bu... | 9,471,883 | D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D020684:Cystoscopes; D019723:Endoscopes; D006801:Humans; D007669:Kidney Calculi; D008096:Lithotripsy; D009403:Nephrostomy, Percutaneous; D011183:Postoperative Complications; D012008:Recurrence; D016896:Treatment Outcome; D014514:Ureteral Calculi; D020709:Uret... | Acta urologica Belgica | 1,997 | ||
Visual problems among people with mental retardation. | Vision impairment can be a debilitating condition, affecting not only the social, emotional, mental and physical functioning of an individual, but also the individual's ability to perform basic and instrumental activities of daily living. Scant knowledge exists about visual impairment among people with mental retardati... | 10.1097/00004356-200306000-00012 | 12,799,611 | D000328:Adult; D005260:Female; D006801:Humans; D008607:Intellectual Disability; D007407:Interviews as Topic; D007557:Israel; D008297:Male; D008875:Middle Aged; D020380:Needs Assessment; D011446:Prospective Studies; D014786:Vision Disorders; D015351:Vision Screening | International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation | 2,003 | |
Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis. | We used coding and noncoding polymorphisms evenly spaced across the ABCB1/MDR1 gene to perform association analysis in Slovenian patients with inflammatory bowel diseases and to obtain haplotype structure and patterns of linkage disequilibrium (LD) in the MDR1 gene. A disease association study was performed in 307 IBD ... | 10.1038/sj.gene.6364123 | 15,505,619 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003093:Colitis, Ulcerative; D016001:Confidence Intervals; D003424:Crohn Disease; D005260:Female; D019450:Genes, MDR; D006239:Haplotypes; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011110:Polymorphism, Genetic | Genes and immunity | 2,004 | |
Resistance to kynurenic acid of the NMDA receptor-dependent toxicity of 3-nitropropionic acid and cyanide in cerebellar granule neurons. | During cerebral hypoxia or ischaemia, mitochondrial dysfunction is induced which can lead to free radical production and cell death. This phenomenon is mimicked by the acute administration of mitochondrial poisons such as 3-nitropropionic acid (3-NPA) and potassium cyanide (KCN), with the production of reactive molecul... | 10.1016/j.brainres.2008.04.013 | 18,486,115 | D000818:Animals; D016923:Cell Death; D002478:Cells, Cultured; D002531:Cerebellum; D004305:Dose-Response Relationship, Drug; D045222:Electron Transport Chain Complex Proteins; D004791:Enzyme Inhibitors; D007736:Kynurenic Acid; D008928:Mitochondria; D033681:Mitochondrial Membrane Transport Proteins; D000083162:Mitochondr... | Brain research | 2,008 | D045222:Electron Transport Chain Complex Proteins; D004791:Enzyme Inhibitors; D033681:Mitochondrial Membrane Transport Proteins; D000083162:Mitochondrial Permeability Transition Pore; D018696:Neuroprotective Agents; D009498:Neurotoxins; D009574:Nitro Compounds; D011422:Propionates; D016194:Receptors, N-Methyl-D-Asparta... |
Sinus pause during nerve integrity monitoring tube insertion following anesthetic induction with a low-dose neuromuscular blocking agent: A CARE-compliant case report. | RATIONALE
Nerve integrity monitoring (NIM) tubes are commonly used in thyroid surgery to prevent recurrent laryngeal nerve injury. To achieve the optimal electromyographic signal for NIM as intraoperative neural monitoring (IONM), the neuromuscular blocking agent (NMBA) dose should be low. The use of a low-dose NMBA in... | 10.1097/MD.0000000000026683 | 34,398,038 | D000758:Anesthesia; D001145:Arrhythmias, Cardiac; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D007442:Intubation, Intratracheal; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents; D013965:Thyroidectomy | Medicine | 2,021 | D009466:Neuromuscular Blocking Agents |
Quality assurance in emergency medical service systems in Michigan: report of a survey. | To determine the characteristics and effects of quality assurance programs in emergency medical service (EMS) systems in Michigan, medical directors of all EMS medical control authorities in Michigan were mailed a survey consisting of 14 closed-ended and open-ended questions including 2 using a subjective continuum sca... | 10.1016/s0097-5990(16)30490-0 | 1,792,038 | D004632:Emergency Medical Services; D006282:Health Personnel; D006801:Humans; D008824:Michigan; D008486:Physician Executives; D011785:Quality Assurance, Health Care; D012955:Societies, Medical; D011795:Surveys and Questionnaires | QRB. Quality review bulletin | 1,991 | |
Mycobacterium bovis BCG Given at Birth Followed by Inactivated Respiratory Syncytial Virus Vaccine Prevents Vaccine-Enhanced Disease by Promoting Trained Macrophages and Resident Memory T Cells. | Respiratory syncytial virus (RSV) infects more than 60% of infants in their first year of life. Since an experimental formalin-inactivated (FI) RSV vaccine tested in the 1960s caused enhanced respiratory disease (ERD), few attempts have been made to vaccinate infants. ERD is characterized by Th2-biased responses, lung ... | 10.1128/jvi.01764-22 | 36,779,760 | D000818:Animals; D051379:Mice; D001500:BCG Vaccine; D008168:Lung; D008264:Macrophages; D008807:Mice, Inbred BALB C; D018357:Respiratory Syncytial Virus Infections; D022261:Respiratory Syncytial Virus Vaccines; D018113:Respiratory Syncytial Virus, Human; D013154:Spleen; D018417:Th1 Cells; D015164:Vaccines, Inactivated | Journal of virology | 2,023 | D001500:BCG Vaccine; D022261:Respiratory Syncytial Virus Vaccines; D015164:Vaccines, Inactivated |
Effects of cholecalciferol on the translocation of calcium by non-everted chick ileum in vitro. | An apparatus is described that allows perfusion of a non-everted segment of intestine in vitro and the study of the accumulation of substances within the mucosal cells. The translocation of Ca(2+) by rachitic-chick ileum and the effect of pretreatment with cholecalciferol was investigated, with the following conclusion... | 10.1042/bj1520181 | 177,000 | D000693:Anaerobiosis; D000818:Animals; D001692:Biological Transport; D002118:Calcium; D002645:Chickens; D002762:Cholecalciferol; D004024:Dicyclohexylcarbodiimide; D004058:Diffusion; D004594:Electrophysiology; D004976:Ethacrynic Acid; D005998:Glycine; D007082:Ileum; D066298:In Vitro Techniques; D007408:Intestinal Absorp... | The Biochemical journal | 1,975 | D014325:Tromethamine; D014867:Water; D002762:Cholecalciferol; D012967:Sodium Dodecyl Sulfate; D008353:Mannitol; D004024:Dicyclohexylcarbodiimide; D012964:Sodium; D004976:Ethacrynic Acid; D002118:Calcium; D005998:Glycine; D007460:Iodoacetamide |
[Masseter strength in patients with motor neuron disease]. | Although masseter muscles play an essential role in digestion, masseter strength in patients with motor neuron diseases has not been well studied. The purpose of this study is to evaluate the masseter strength in healthy volunteers (n = 13, mean age +/- S.D.: 58 +/- 10 years) and in patients with motor neuron diseases ... | 12,607,975 | D001732:Bite Force; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016472:Motor Neuron Disease | Rinsho shinkeigaku = Clinical neurology | 2,002 | ||
Cost-effectiveness of intracytoplasmic sperm injection in comparison with donor insemination. | BACKGROUND
Due to the need for cost containment in the national health services in many countries, there is a demand for analysis of both medical and cost benefits of new technologies. Intracytoplasmic sperm injection has in recent years been proved to be the method of choice for treating severe infertility. It also ne... | 10.3109/00016349609065737 | 8,906,008 | D003362:Cost-Benefit Analysis; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007248:Infertility, Male; D007317:Insemination, Artificial, Homologous; D008297:Male | Acta obstetricia et gynecologica Scandinavica | 1,996 | |
Redistribution of apolipoproteins C removed from human very low density lipoprotein during in vitro lipolysis by lipoprotein lipase. | In order to localize the labelled apolipoproteins C removed from Very Low Density Lipoproteins (VLDL) during lipolysis by lipoprotein lipase, we used human VLDL labelled with 125I-labelled apolipoproteins C and employed density gradient ultracentrifugation to analyze lipolytic products. Triacylglycerol hydrolysis occur... | 10.1016/s0300-9084(81)80081-8 | 7,260,173 | D001053:Apolipoproteins; D001056:Apolipoproteins C; D002499:Centrifugation, Density Gradient; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D066298:In Vitro Techniques; D008066:Lipolysis; D008071:Lipoprotein Lipase; D008075:Lipoproteins, HDL; D053439:Lipoproteins, HDL2; D053440:Lipoproteins, HDL3; D00807... | Biochimie | 1,981 | D001053:Apolipoproteins; D001056:Apolipoproteins C; D008075:Lipoproteins, HDL; D053439:Lipoproteins, HDL2; D053440:Lipoproteins, HDL3; D008079:Lipoproteins, VLDL; D014280:Triglycerides; D008071:Lipoprotein Lipase |
[Identification and functional analysis of NIFA from Mesorhizobium huakuii 159]. | The nifA gene from Mesorhizobium huakuii 159 was identified and sequenced. An open reading frame coding for 44734D. NifA protein would detected. Comparison of the deduced amino acid sequence with other NifA proteins revealed the presence of the conserved central domain and the C-terminal DNA-binding domains. But the pr... | 12,548,989 | D000595:Amino Acid Sequence; D001426:Bacterial Proteins; D001483:Base Sequence; D003001:Cloning, Molecular; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D009586:Nitrogen Fixation; D016366:Open Reading Frames; D010641:Phenotype; D010957:Plasmids; D012230:Rhizobiaceae; D0... | Wei sheng wu xue bao = Acta microbiologica Sinica | 2,000 | D001426:Bacterial Proteins; C061338:NifA protein, Bacteria; D014157:Transcription Factors | |
[Anthropometry and female breast cancer: a prospective cohort study in urban Shanghai]. | OBJECTIVE
To investigate the association between anthropometry and risk of breast cancer among pre-and post-menopausal women in urban Shanghai.
METHODS
A total of 73 461 female residents aged 40 to 70 years in urban Shanghai were recruited in a prospective cohort study (the Shanghai women's health study) during 1997 ... | 17,152,508 | D000328:Adult; D000368:Aged; D000886:Anthropometry; D001943:Breast Neoplasms; D002681:China; D005260:Female; D006801:Humans; D008875:Middle Aged; D056128:Obesity, Abdominal; D017698:Postmenopause; D012306:Risk; D014505:Urban Population; D015430:Weight Gain | Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi | 2,006 | ||
Psychosocial profile in men and women with unexplained chest pain. | OBJECTIVE
The aim of this study was to compare men and women with unexplained chest pain (UCP) to a randomly selected population sample free of clinical heart disease with regard to sleep problems, mental strain at work, stress at home, negative life events and health-related quality of life (HRQOL).
DESIGN AND SUBJE... | 10.1111/j.1365-2796.2008.01961.x | 18,397,246 | D000328:Adult; D000368:Aged; D002637:Chest Pain; D004522:Educational Status; D054242:Emigrants and Immigrants; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D009784:Occupational Diseases; D011594:Psychometrics; D011788:Quality of Life; D012307:Ris... | Journal of internal medicine | 2,008 | |
Projected near-future CO2 levels increase activity and alter defensive behaviours in the tropical squid Idiosepius pygmaeus. | Carbon dioxide (CO2) levels projected to occur in the oceans by the end of this century cause a range of behavioural effects in fish, but whether other highly active marine organisms, such as cephalopods, are similarly affected is unknown. We tested the effects of projected future CO2 levels (626 and 956 µatm) on the b... | 10.1242/bio.20149894 | 25,326,517 | Biology open | 2,014 | ||
Selective Coherent Anti-Stokes Raman Scattering Microscopy Employing Dual-Wavelength Nanofocused Ultrafast Plasmon Pulses. | Ultrafast surface plasmon polariton (SPP) nanofocusing on a plasmonic metal tapered tip with femtosecond laser pulses enables background-free localized excitation beyond the diffraction limit. We demonstrate simultaneous nanofocusing of ultrafast SPP pulses at 440 and 800 nm, which were coupled with a common diffractio... | 10.1021/acs.nanolett.7b05078 | 29,376,374 | Nano letters | 2,018 | ||
Trimethylamine N-Oxide (TMAO) Inducing Endothelial Injury: UPLC-MS/MS-Based Quantification and the Activation of Cathepsin B-Mediated NLRP3 Inflammasome. | TMAO is a new risk biomarker for cardiovascular disease. With trimethylammonium as its main chemical skeleton, TMAO is structurally similar to many endogenous metabolites, such as acetylcholine, carnitine, phosphorylcholine, etc. The mechanism of TMAO on the pathological process of CVD is still unclear. In this study, ... | 10.3390/molecules28093817 | 37,175,227 | D000818:Animals; D058847:Inflammasomes; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; D042783:Endothelial Cells; D002478:Cells, Cultured; D002401:Cathepsin B; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid; D053719:Tandem Mass Spectrometry; D002318:Cardiovascular Diseases | Molecules (Basel, Switzerland) | 2,023 | D058847:Inflammasomes; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; C005855:trimethyloxamine; D002401:Cathepsin B |
Dispersion and stratification of Per-and polyfluoroalkyl substances (PFAS) in surface and deep-water profiles: A case study of the Biscayne Bay area. | Per-and polyfluoroalkyl substances (PFAS) are a group of synthetic chemical compounds known for their persistent, bioaccumulation and toxic characteristics in all environmental compartments. As industrial and domestic applications of PFAS increase, their discharge into water bodies becomes of human and ecological conce... | 10.1016/j.scitotenv.2023.168413 | 37,949,131 | The Science of the total environment | 2,024 | ||
Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability. | The insulin IGF-1-PI3K-Akt signaling pathway has been suggested to improve cardiac inotropism and increase Ca(2+) handling through the effects of the protein kinase Akt. However, the underlying molecular mechanisms remain largely unknown. In this study, we provide evidence for an unanticipated regulatory function of Ak... | 10.1083/jcb.200805063 | 19,307,602 | D064413:3-Phosphoinositide-Dependent Protein Kinases; D020816:Amino Acid Motifs; D000818:Animals; D020746:Calcium Channels, L-Type; D020013:Calcium Signaling; D002311:Cardiomyopathy, Dilated; D002462:Cell Membrane; D002478:Cells, Cultured; D017124:Conserved Sequence; D004195:Disease Models, Animal; D008297:Male; D00856... | The Journal of cell biology | 2,009 | D020746:Calcium Channels, L-Type; D021122:Protein Subunits; D011993:Recombinant Fusion Proteins; D013629:Tamoxifen; D064413:3-Phosphoinositide-Dependent Protein Kinases; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt |
Severe renal failure and hyperammonemia in a newborn with propionic acidemia: effects of treatment on the clinical course. | Neonatal-onset propionic acidemia (PA), the most common form, is characterized by poor feeding, vomiting, and somnolence in the first days of life in a previously healthy infant, followed by lethargy, seizures, and can progress to coma if not identified and treated appropriately. It is frequently accompanied by metabol... | 10.3109/0886022X.2013.865484 | 24,329,397 | D058186:Acute Kidney Injury; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D022124:Hyperammonemia; D007231:Infant, Newborn; D010530:Peritoneal Dialysis; D056693:Propionic Acidemia | Renal failure | 2,014 | |
Primary leiomyoma: a rare space occupying lesion in the right ventricle. | A case of primary cardiac leiomyoma arising from the infundibulum of the right ventricle of a 24-year-old woman is presented. The mass protruded into the cavity of the right ventricle and caused severe right ventricular outflow tract obstruction. We resected the tumor under cardiopulmonary bypass successfully, and conf... | 24,384,185 | D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006338:Heart Neoplasms; D006352:Heart Ventricles; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma; D035583:Rare Diseases; D014057:Tomography, X-Ray Computed; D016896... | The Annals of thoracic surgery | 2,014 | ||
Negative feedback at kinetochores underlies a responsive spindle checkpoint signal. | Kinetochores are specialized multi-protein complexes that play a crucial role in maintaining genome stability. They bridge attachments between chromosomes and microtubules during mitosis and they activate the spindle assembly checkpoint (SAC) to arrest division until all chromosomes are attached. Kinetochores are able ... | 10.1038/ncb3065 | 25,402,682 | D020816:Amino Acid Motifs; D064107:Aurora Kinase B; D018797:Cell Cycle Proteins; D045744:Cell Line, Tumor; D020090:Chromosome Segregation; D025461:Feedback, Physiological; D006367:HeLa Cells; D006801:Humans; D018386:Kinetochores; D059566:M Phase Cell Cycle Checkpoints; D008869:Microtubule-Associated Proteins; D008870:M... | Nature cell biology | 2,014 | D018797:Cell Cycle Proteins; C472643:Knl1 protein, human; D008869:Microtubule-Associated Proteins; D034741:RNA, Small Interfering; C496644:SGO1 protein, human; C497782:SMAD2 protein, human; D051899:Smad2 Protein; D050257:Tubulin Modulators; D011505:Protein-Tyrosine Kinases; C576921:AURKB protein, human; D064107:Aurora ... |
Oleanolic Acid, a plant triterpenoid, significantly improves survival and function of islet allograft. | BACKGROUND.: Oleanolic acid (OA) is a ubiquitous triterpenoid, with potent antioxidant and anti-inflammatory properties. Here, we tested whether these combined properties of OA can prevent nonimmunologic primary nonfunctioning and immunologic phenomena ascribed to graft rejection hence prolong islet allograft survival.... | 10.1097/TP.0b013e3181b9cbc4 | 19,855,244 | D000818:Animals; D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D003921:Diabetes Mellitus, Experimental; D006085:Graft Survival; D007328:Insulin; D016381:Islets of Langerhans Transplantation; D008070:Lipopolysaccharides; D017737:Macrophages, Peritoneal; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; ... | Transplantation | 2,009 | D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D007328:Insulin; D008070:Lipopolysaccharides; D017382:Reactive Oxygen Species; D009828:Oleanolic Acid |
Real-time Mental Health Impact of the COVID-19 Pandemic on College Students: Ecological Momentary Assessment Study. | BACKGROUND
College students' mental health may be disproportionally affected by the COVID-19 pandemic because of the abrupt shift off campus and subsequent loss of a social network and potential long-term impact on job prospects.
OBJECTIVE
We sought to assess the nature of COVID-19's mental health impact among a samp... | 10.2196/24815 | 33,207,308 | JMIR mental health | 2,020 | ||
[Insulin resistance]. | There are several mechanisms about high blood pressure induced by insulin resistance in type 2 diabetes. Hyperinsulinemia is rare in Japanese type 2 diabetic patients. Therefore, hyperinsulinemia is not a major cause of high blood pressure in Japanese type 2 diabetic patients. Diabetic nephropathy was associated with h... | 12,877,071 | D001161:Arteriosclerosis; D003924:Diabetes Mellitus, Type 2; D003928:Diabetic Nephropathies; D018450:Disease Progression; D004730:Endothelium, Vascular; D006801:Humans; D006973:Hypertension; D007328:Insulin; D007333:Insulin Resistance; D014664:Vasodilation | Nihon rinsho. Japanese journal of clinical medicine | 2,003 | D007328:Insulin | |
Costs and cost-effectiveness of a large-scale mass testing and treatment intervention for malaria in Southern Province, Zambia. | BACKGROUND
A cluster, randomized, control trial of three dry-season rounds of a mass testing and treatment intervention (MTAT) using rapid diagnostic tests (RDTs) and artemether-lumefantrine (AL) was conducted in four districts in Southern Province, Zambia.
METHODS
Data were collected on the costs and logistics of th... | 10.1186/s12936-015-0722-3 | 25,985,992 | D000962:Antimalarials; D000077611:Artemether, Lumefantrine Drug Combination; D037621:Artemisinins; D003362:Cost-Benefit Analysis; D003955:Diagnostic Tests, Routine; D004338:Drug Combinations; D004983:Ethanolamines; D005449:Fluorenes; D008288:Malaria; D008403:Mass Screening; D015024:Zambia | Malaria journal | 2,015 | D000962:Antimalarials; D000077611:Artemether, Lumefantrine Drug Combination; D037621:Artemisinins; D004338:Drug Combinations; D004983:Ethanolamines; D005449:Fluorenes |
New insights into family relationships within the avian superfamily Sylvioidea (Passeriformes) based on seven molecular markers. | BACKGROUND
The circumscription of the avian superfamily Sylvioidea is a matter of long ongoing debate. While the overall inclusiveness has now been mostly agreed on and 20 families recognised, the phylogenetic relationships among the families are largely unknown. We here present a phylogenetic hypothesis for Sylvioidea... | 10.1186/1471-2148-12-157 | 22,920,688 | D000818:Animals; D030161:Avian Proteins; D019143:Evolution, Molecular; D005819:Genetic Markers; D054643:INDEL Mutation; D046109:Passeriformes; D010802:Phylogeny | BMC evolutionary biology | 2,012 | D030161:Avian Proteins; D005819:Genetic Markers |
Stochastic resonance emergence from a minimalistic behavioral rule. | Stochastic resonance (SR) is a phenomenon occurring in nonlinear systems by which the ability to process information, for instance the detection of weak signals is statistically enhanced by a non-zero level of noise. SR effects have been observed in a great variety of systems, comprising electronic circuits, optical de... | 10.1016/j.jtbi.2011.01.002 | 21,216,254 | D001419:Bacteria; D002633:Chemotaxis; D003198:Computer Simulation; D008390:Markov Chains; D008954:Models, Biological; D016011:Normal Distribution; D013269:Stochastic Processes | Journal of theoretical biology | 2,011 | |
Institutional pioneers in world politics: Regional institution building and the influence of the European Union. | What drives processes of institution building within regional international organizations? We challenge those established theories of regionalism, and of institutionalized cooperation more broadly, that treat different organizations as independent phenomena whose evolution is conditioned primarily by internal causal fa... | 10.1177/1354066116674261 | 29,400,350 | European journal of international relations | 2,017 | ||
Upper and lower respiratory tract infections. Nursing intervention. | Proper nursing intervention can assist in the reduction of nosocomial respiratory tract infections. Maintaining the integrity of the patient's respiratory defense mechanisms and/or augmenting those that are impaired helps to control endogenous factors that can contribute to infection. Nursing implications in controllin... | 7,005,874 | D003428:Cross Infection; D006801:Humans; D001239:Inhalation; D007442:Intubation, Intratracheal; D009910:Oral Hygiene; D011175:Positive-Pressure Respiration; D011187:Posture; D012141:Respiratory Tract Infections; D013396:Suction; D014140:Tracheotomy | The Nursing clinics of North America | 1,980 | ||
[Description of psychosocial risk factors in four companies]. | OBJECTIVE
To describe the distribution of work-related psychosocial risk factor scores in four companies according to the personal and occupational characteristics of the workers.
METHODS
Cross-sectional study of a sample of 890 workers in four companies who participated in this study voluntarily. The overall respons... | 10.1016/s0213-9111(02)71665-8 | 12,057,177 | D000288:Administrative Personnel; D000328:Adult; D003430:Cross-Sectional Studies; D004522:Educational Status; D004581:Electronics; D004651:Employment; D005160:Facility Design and Construction; D005260:Female; D006801:Humans; D007221:Industry; D008297:Male; D001523:Mental Disorders; D008875:Middle Aged; D009784:Occupati... | Gaceta sanitaria | 2,002 | |
Hyperoxia for performance and training. | Recent technological developments have made it possible to use hyperoxia as an enhancement aid during training. Athletes wearing a mask can breathe a higher fraction of oxygen from a stationary or portable apparatus while exercising. A large body of evidence indicates that the oxygen transport capacity, lactate metabol... | 10.1080/02640414.2017.1398893 | 29,115,912 | D000222:Adaptation, Physiological; D001775:Blood Circulation; D004734:Energy Metabolism; D015444:Exercise; D017079:Exercise Tolerance; D006801:Humans; D018496:Hyperoxia; D019344:Lactic Acid; D018763:Muscle Fatigue; D018482:Muscle, Skeletal; D010101:Oxygen Consumption; D064797:Physical Conditioning, Human; D010807:Physi... | Journal of sports sciences | 2,018 | D019344:Lactic Acid |
Phytobiotics blend as a dietary supplement for Nile tilapia health improvement. | Functional additives of natural origin included as dietary supplements have become an alternative to synthetic antibiotics to improve health and resistance to ecologically correct pathogenic diseases in fish farming. We tested whether incorporating a mixture of phytobiotics such as volatile oils of thyme, red thyme and... | 10.1016/j.fsi.2021.05.010 | 34,004,271 | D016980:Aeromonas hydrophila; D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D000900:Anti-Bacterial Agents; D023681:Cichlids; D004032:Diet; D019587:Dietary Supplements; D000077422:Enrofloxacin; D005393:Fish Diseases; D016905:Gram-Negative Bacterial Infections; D032411:Lippia; ... | Fish & shellfish immunology | 2,021 | D000900:Anti-Bacterial Agents; D010938:Plant Oils; D000077422:Enrofloxacin |
Primate genomes offer new view of human health and our past. | Sequencing efforts may also aid primate conservation. | 10.1126/science.adi9903 | 37,262,143 | D000818:Animals; D006801:Humans; D056727:Endangered Species; D016678:Genome; D011323:Primates; D017422:Sequence Analysis, DNA; D014644:Genetic Variation; D006262:Health | Science (New York, N.Y.) | 2,023 | |
Peroxidase activity associated with suberization processes of the muskmelon (Cucumis melo) rind. | The rind of fruits of muskmelon (Cucumis melo L. var. reticulatus) contains a network of suberized tissue referred to as the 'netting', and peroxidase (EC 1.11.1.7) activity is necessary to the polymerization of the aromatic domain of suberin. Peroxidase activity increased dramatically during the early stages of melon ... | 10.1111/j.0031-9317.2004.00301.x | 15,086,828 | Physiologia plantarum | 2,004 | ||
Fostering human rights through TalkBank. | In accord with articles 19 and 27 of the Universal Declaration of Human Rights, people with speech and language disorders have the right to receive maximal benefit from academic research on speech and language acquisition and disorders. To evaluate the diverse nature of speech and language disorders, this research must... | 10.1080/17549507.2018.1392609 | 29,124,960 | D066264:Datasets as Topic; D006806:Human Rights; D006801:Humans; D007805:Language Development Disorders; D013066:Speech-Language Pathology | International journal of speech-language pathology | 2,018 | |
Effect of environmental fluctuations on invasion fronts. | We determine the density profile and velocity of invasion fronts in one-dimensional infinite habitats in the presence of environmental fluctuations. The population dynamics is reformulated in terms of a stochastic reaction-diffusion equation and is reduced to a deterministic equation that incorporates the systematic co... | 10.1016/j.jtbi.2011.04.025 | 21,549,716 | D003163:Competitive Behavior; D004058:Diffusion; D004777:Environment; D008954:Models, Biological; D011156:Population Density; D011157:Population Dynamics; D013269:Stochastic Processes; D013997:Time Factors | Journal of theoretical biology | 2,011 | |
Multiple pulmonary nodules manifested in a patient with NK cell granular lymphocyte proliferative disorder. | An 18-year-old man was admitted to our hospital with high temperature and dyspnea. A chest radiograph revealed the presence of multiple round nodules compatible with a metastatic lung cancer. The peripheral white blood cell count was 22,000/mm3 and more than 85 percent were atypical large lymphocytes with azurophilic g... | 10.1378/chest.105.6.1893 | 7,515,779 | D000293:Adolescent; D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D019002:CD56 Antigen; D002455:Cell Division; D004854:Herpesvirus 4, Human; D006801:Humans; D007244:Infectious Mononucleosis; D007694:Killer Cells, Natural; D008168:Lung; D008171:Lung Diseases; D008232:Lymphoproliferative Disorder... | Chest | 1,994 | D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D019002:CD56 Antigen |
Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells. | Zinc oxide nanoparticles (ZnONPs) hold great promise for biomedical applications. Previous studies have revealed that ZnONPs exposure can induce toxicity in endothelial cells, but the underlying mechanisms have not been fully elucidated. In this study, we report that ZnONPs can induce ferroptosis of both HUVECs and EA.... | 10.1080/15548627.2021.1911016 | 33,843,441 | D000818:Animals; D001343:Autophagy; D042783:Endothelial Cells; D000079403:Ferroptosis; D051379:Mice; D053758:Nanoparticles; D015034:Zinc Oxide | Autophagy | 2,021 | D015034:Zinc Oxide |
Ability of base analogs to induce the SOS response: effect of a dam mutation and mismatch repair system. | 2-Aminopurine, 2-amino-N6-hydroxyadenine, 2-amino-N6-methoxyadenine and 2-amino-N6-methyl-N6-hydroxyadenine (but not N4-hydroxycytidine), strong mutagens of base analog type, may induce the SOS response in E. coli cells. This ability is greatly enhanced in dam3 mutants and abolished in dam3mutS, dam3mutH, and dam3mutL ... | 10.1007/BF00331349 | 3,937,030 | D004260:DNA Repair; D004926:Escherichia coli; D005786:Gene Expression Regulation; D005798:Genes, Bacterial; D009153:Mutagens; D009154:Mutation; D011401:Promoter Regions, Genetic; D011687:Purines; D014775:Virus Activation; D001616:beta-Galactosidase | Molecular & general genetics : MGG | 1,985 | D009153:Mutagens; D011687:Purines; D001616:beta-Galactosidase |
CSF Rhinorrhea After Endonasal Intervention to the Skull Base (CRANIAL) - Part 2: Impact of COVID-19. | BACKGROUND
During the coronavirus disease 2019 (COVID-19) pandemic, concerns have been raised regarding the increased risk of perioperative mortality for patients with COVID-19, and the transmission risk to healthcare workers, especially during endonasal neurosurgical operations. The Pituitary Society has produced reco... | 10.1016/j.wneu.2020.12.169 | 33,444,833 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000086382:COVID-19; D000086742:COVID-19 Testing; D002559:Cerebrospinal Fluid Rhinorrhea; D002648:Child; D015331:Cohort Studies; D004724:Endoscopy; D005260:Female; D006801:Humans; D007494:Ireland; D008297:Male; D008403:Mass Screening; D008875:M... | World neurosurgery | 2,021 | |
Review article: coagulation disorders in chronic liver disease. | BACKGROUND
The liver is the site for synthesis of the vast majority of proteins that play a central role in maintaining hemostasis, by participating in the regulation of coagulation and fibrinolysis.
AIM
To summarize the available data on the impact of coagulation disorders in patients with chronic liver disease.
R... | 10.1111/j.1365-2036.2007.03509.x | 17,958,516 | D001778:Blood Coagulation Disorders; D001791:Blood Platelet Disorders; D005342:Fibrinolysis; D006487:Hemostasis; D006801:Humans; D008107:Liver Diseases | Alimentary pharmacology & therapeutics | 2,007 | |
Stress and its predictors in pregnant women: a study in Saudi Arabia. | BACKGROUND
Although stress during pregnancy has negative effects on children's development and pregnant women's health, no study has assessed stress and its predictors among pregnant Saudi women. The aim of this study was to assess stress and identify its predictors in a sample of pregnant Saudi women.
METHODS
A corr... | 10.2147/PRBM.S131474 | 28,435,340 | Psychology research and behavior management | 2,017 | ||
Combination of metformin and RG7388 enhances inhibition of growth and induction of apoptosis of ovarian cancer cells through the PI3K/AKT/mTOR pathway. | Ovarian cancer is a gynecological cancer that has the highest mortality rate and is often resistant to conventional treatments. Therefore, development of new therapies is essential. Metformin (MET), which is the priority drug for treatment of type 2 diabetes, has received increasing attention because of its anti-tumor ... | 10.1016/j.bbrc.2020.09.135 | 33,051,060 | D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols; D017209:Apoptosis; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D005260:Female; D006801:Humans; D020935:MAP Kinase Signaling System; D008687:Metformin; D008819:Mice, Nude; D010051:Ovarian Neoplasms; D058539:Phosphatidylinositol 3-Kinase; ... | Biochemical and biophysical research communications | 2,020 | D011759:Pyrrolidines; C586849:RG7388; D017382:Reactive Oxygen Species; D062366:para-Aminobenzoates; D008687:Metformin; C546842:MTOR protein, human; D058539:Phosphatidylinositol 3-Kinase; D051057:Proto-Oncogene Proteins c-akt; D058570:TOR Serine-Threonine Kinases |
Human circadian system causes a morning peak in prothrombotic plasminogen activator inhibitor-1 (PAI-1) independent of the sleep/wake cycle. | Serious adverse cardiovascular events peak in the morning, possibly related to increased thrombosis in critical vessels. Plasminogen activator inhibitor-1 (PAI-1), which inhibits fibrinolysis, is a key circulating prothrombotic factor that rises in the morning in humans. We tested whether this morning peak in PAI-1 is ... | 10.1182/blood-2013-07-517060 | 24,200,683 | D000328:Adult; D001519:Behavior; D001777:Blood Coagulation; D002940:Circadian Rhythm; D015444:Exercise; D005260:Female; D005342:Fibrinolysis; D005786:Gene Expression Regulation; D006801:Humans; D008297:Male; D017395:Plasminogen Activator Inhibitor 1; D012307:Risk Factors; D012890:Sleep; D013696:Temperature; D013997:Tim... | Blood | 2,014 | D017395:Plasminogen Activator Inhibitor 1 |
Brewing spoilage Lactobacilli detected using monoclonal antibodies to bacterial surface antigens. | A panel of thirteen monoclonal antibodies (Mabs) was assembled that reacts with surface antigens on eight of eleven Lactobacillus brewing spoilage organisms, including one or more of L. brevis, L. buchneri, L. casei-alactosus, L. plantarum, or unspeciated isolate(s). Immunoblotting was done to identify the antigens inv... | 10,349,721 | D000818:Animals; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D000954:Antigens, Surface; D001515:Beer; D015151:Immunoblotting; D007124:Immunoenzyme Techniques; D007778:Lactobacillus; D051379:Mice; D008807:Mice, Inbred BALB C; D012680:Sensitivity and Specificity | Canadian journal of microbiology | 1,999 | D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D000954:Antigens, Surface | |
Hydrogen bond strength and bond geometry in cyclic dimers of crystalline carboxylic acids. | In a study of 101 crystal structures of carboxylic acids we have observed a clear trend in the difference between the formally single and formally double C-O bond distances, as observed by X-ray diffraction, with a clear-cut distinction between aromatic acids, where the two distances are similar, and non-aromatic acids... | 10.1107/S0108768108007556 | 18,490,831 | Acta crystallographica. Section B, Structural science | 2,008 | ||
Safety and Efficacy of Bariatric Surgery in Advanced Liver Fibrosis. | BACKGROUND
There is limited data on the safety and efficacy of metabolic and bariatric (MBS) surgery in patients with advanced liver fibrosis.
METHODS
This is a retrospective analysis of data of patients with advanced liver fibrosis undergoing MBS at a tertiary care centre. Weight loss and complications were analysed... | 10.1007/s11695-020-04827-3 | 33,900,587 | D050110:Bariatric Surgery; D054459:Elasticity Imaging Techniques; D006801:Humans; D008099:Liver; D008103:Liver Cirrhosis; D009767:Obesity, Morbid; D012189:Retrospective Studies | Obesity surgery | 2,020 | |
Identification of immunodominant T cell epitopes induced by natural Zika virus infection. | Zika virus (ZIKV) is a flavivirus primarily transmitted by Aedes species mosquitoes, first discovered in Africa in 1947, that disseminated through Southeast Asia and the Pacific Islands in the 2000s. The first ZIKV infections in the Americas were identified in 2014, and infections exploded through populations in Brazil... | 10.3389/fimmu.2023.1247876 | 37,705,976 | D000328:Adult; D000818:Animals; D005260:Female; D011247:Pregnancy; D006801:Humans; D000071243:Zika Virus Infection; D000071244:Zika Virus; D018984:Epitopes, T-Lymphocyte; D005805:Genes, MHC Class I; D000330:Aedes | Frontiers in immunology | 2,023 | D018984:Epitopes, T-Lymphocyte |
Diversity of nifH gene pools in the rhizosphere of two cultivars of sorghum (Sorghum bicolor) treated with contrasting levels of nitrogen fertilizer. | The diversity of nitrogen-fixing bacteria was assessed in the rhizospheres of two cultivars of sorghum (IS 5322-C and IPA 1011) sown in Cerrado soil amended with two levels of nitrogen fertilizer (12 and 120 kg ha(-1)). The nifH gene was amplified directly from DNA extracted from the rhizospheres, and the PCR products ... | 10.1111/j.1574-6968.2007.00975.x | 18,070,072 | D001419:Bacteria; D044822:Biodiversity; D004269:DNA, Bacterial; D005308:Fertilizers; D008969:Molecular Sequence Data; D010088:Oxidoreductases; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D012988:Soil Microbiology; D045868:Sorghum | FEMS microbiology letters | 2,008 | D004269:DNA, Bacterial; D005308:Fertilizers; D010088:Oxidoreductases; C029130:nitrogenase reductase |
Thermomechanical Characterization and Modeling of NiTi Shape Memory Alloy Coil Spring. | Today, shape memory alloys (SMAs) have important applications in several fields of science and engineering. This work reports the thermomechanical behavior of NiTi SMA coil springs. The thermomechanical characterization is approached starting from mechanical loading-unloading tests under different electric current inte... | 10.3390/ma16103673 | 37,241,299 | Materials (Basel, Switzerland) | 2,023 | ||
Assessment of knee extensor and flexor function using isokinetic test in COPD: impact on exercise capacity. | OBJECTIVE: To quantify the relationship between strength and endurance of knee extensor and flexor and exercise capacity in patients with chronic obstructive pulmonary disease (COPD).METHODS: A total of 108 patients with stable COPD (age: 65 years, IQR25-75: 59-72) were enrolled in this cross-sectional study. Knee exte... | 10.5588/ijtld.19.0588 | 32,912,381 | D000368:Aged; D003430:Cross-Sectional Studies; D005080:Exercise Test; D017079:Exercise Tolerance; D005541:Forced Expiratory Volume; D006801:Humans; D053580:Muscle Strength; D029424:Pulmonary Disease, Chronic Obstructive | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | 2,020 | |
Scanographic study of the calcaneus: normal anatomy and clinical applications. | To facilitate the interpretation of the scanographic findings in fractures of the calcaneus, the authors have achieved an anatomo-radiologic correlation in terms of the classical coronal, sagittal and horizontal planes. Clinically, the sagittal plane can be obtained only by reconstruction. The 2 other planes permit stu... | 10.1007/BF02107903 | 3,145,572 | D002111:Calcaneus; D050723:Fractures, Bone; D006801:Humans; D013380:Subtalar Joint; D013628:Talus; D014057:Tomography, X-Ray Computed | Surgical and radiologic anatomy : SRA | 1,988 | |
Body mass index and mortality in an ethnically diverse population: the Multiethnic Cohort Study. | Body mass index (BMI) has been strongly related to overall mortality, but the consistency of this association across diverse ethnic groups and the effects of early adult BMI versus BMI in later adulthood have not been adequately studied. A prospective analysis was performed using data from 183,211 adults aged 45-75 who... | 10.1007/s10654-012-9695-5 | 22,644,110 | D017677:Age Distribution; D000368:Aged; D015992:Body Mass Index; D002140:California; D015331:Cohort Studies; D005006:Ethnicity; D005260:Female; D005500:Follow-Up Studies; D006254:Hawaii; D006801:Humans; D008297:Male; D008875:Middle Aged; D009026:Mortality; D050177:Overweight; D016016:Proportional Hazards Models; D01144... | European journal of epidemiology | 2,012 | |
Can supervising self-harm be part of ethical nursing practice? | It was reported in 2006 that a regime of 'supervised self harm' had been implemented at St George's Hospital, Stafford. This involves patients with a history of self-harming behaviour being offered both emotional and practical support to enable them to do so. This support can extend to the provision of knives or razors... | 10.1177/0969733010386166 | 21,285,199 | D004993:Ethics, Nursing; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D024802:Nurse's Role; D009723:Nurse-Patient Relations; D009730:Nursing Assessment; D011568:Psychiatric Nursing; D016728:Self-Injurious Behavior; D006113:United Kingdom | Nursing ethics | 2,011 | |
Thiamine and Biotin: Relevance in the Production of Volatile and Non-Volatile Compounds during Saccharomyces cerevisiae Alcoholic Fermentation in Synthetic Grape Must. | Vitamins are major cofactors to numerous key metabolic pathways in enological yeasts, and both thiamine and biotin, notably, are believed to be essential to yeast fermentation and growth, respectively. In order to further assess and clarify their role in winemaking, and in the resulting wine, alcoholic fermentations of... | 10.3390/foods12050972 | 36,900,489 | Foods (Basel, Switzerland) | 2,023 | ||
Relationship between metabolic syndrome and intake of ultra-processed foods in Korean adults: based on 6th and 7th Korea National Health and Nutrition Examination Survey (2013-2018). | BACKGROUND/OBJECTIVES
Metabolic syndrome is closely associated with lifestyle factors, including diet and nutritional intake. Modern trends show a shift in food consumption from healthy home-cooked meals to processed and instant foods. Therefore, this study analyzed the association between ultra-processed food intake a... | 10.4162/nrp.2023.17.4.735 | 37,529,274 | Nutrition research and practice | 2,023 | ||
Isolation and characterization of cyanogen bromide fragments of the A and B chains of the antitumor toxin ricin D. | Both the A and B chains of ricin D consist of four CNBr fragments. These fragments have been isolated from the separated chains of S-carboxymethylated ricin D obtained from the small bean variety of Ricinus communis. The peptides have been characterized by molecular weight, amino acid composition and amino terminal seq... | 10.1111/j.1399-3011.1980.tb02954.x | 7,461,902 | D000595:Amino Acid Sequence; D001322:Autoanalysis; D003488:Cyanogen Bromide; D046911:Macromolecular Substances; D010446:Peptide Fragments; D012276:Ricin | International journal of peptide and protein research | 1,980 | D046911:Macromolecular Substances; D010446:Peptide Fragments; D012276:Ricin; D003488:Cyanogen Bromide |
Effects of lithium carbonate (Li2CO3) on in-vitro-cultured normal human skin explants. | The early morphological changes induced by lithium carbonate, a well-known psoriasis-provoking drug, were studied on cultured skin. Normal human skin from patients undergoing mastectomy was cultured in the presence of 3 mM, 6 mM and 10 mM of Li2CO3 for 4 days. The morphological changes were then evaluated by three obse... | 10.1046/j.1468-3083.2000.00031.x | 10,972,093 | D002478:Cells, Cultured; D004817:Epidermis; D006801:Humans; D015603:Keratinocytes; D016651:Lithium Carbonate; D011565:Psoriasis; D012867:Skin | Journal of the European Academy of Dermatology and Venereology : JEADV | 2,000 | D016651:Lithium Carbonate |
AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells. | BACKGROUND
Fenretinide (4-HPR) is a synthetic retinoid that exhibits potent antitumor and chemopreventive activities against different malignancies, including ovarian tumors. We previously showed that in ovarian cancer cells, 4-HPR induces apoptosis through a signaling cascade starting from reactive oxygen species (ROS... | 10.1371/journal.pone.0039968 | 22,761,939 | D017209:Apoptosis; D002455:Cell Division; D005260:Female; D017313:Fenretinide; D006801:Humans; D009363:Neoplasm Proteins; D010051:Ovarian Neoplasms; D011518:Proto-Oncogene Proteins; D015398:Signal Transduction; D015854:Up-Regulation | PloS one | 2,012 | C091736:MLLT11 protein, human; D009363:Neoplasm Proteins; D011518:Proto-Oncogene Proteins; D017313:Fenretinide |
Phonological working memory and reading in test anxiety. | Texts were presented sentence by sentence (Experiment 1) or word by word (Experiment 2) at a fixed rate to subjects high or low in test anxiety, under various conditions: no interference, concurrent articulatory suppression, and concurrent irrelevant speech (presented auditorily). High-anxiety subjects produced overt a... | 10.1080/096582196388960 | 8,735,612 | D000328:Adult; D000704:Analysis of Variance; D001007:Anxiety; D005260:Female; D006801:Humans; D007206:Individuality; D007807:Language Tests; D008297:Male; D008568:Memory; D008606:Mental Processes; D011932:Reading; D013315:Stress, Psychological; D013732:Test Anxiety Scale | Memory (Hove, England) | 1,996 | |
Effect of somatosensory stimulation of two and three nerves on upper limb function in healthy individuals. | BACKGROUND AND PURPOSE
Improvement in motor function has been reported in healthy subjects following somatosensory stimulation (SS) of individual upper limb peripheral nerves. This effect could have beneficial applications in rehabilitation, but there is little knowledge of the effects of stimulating multiple upper lim... | 10.1002/pri.515 | 21,748,825 | D000203:Activities of Daily Living; D000328:Adult; D005260:Female; D006225:Hand; D018737:Hand Strength; D006801:Humans; D008297:Male; D008475:Median Nerve; D009043:Motor Activity; D018763:Muscle Fatigue; D053580:Muscle Strength; D011826:Radial Nerve; D016037:Single-Blind Method; D013997:Time Factors; D004561:Transcutan... | Physiotherapy research international : the journal for researchers and clinicians in physical therapy | 2,012 | |
Hypertrophic olivary degeneration - a report of two cases. | Hypertrophic olivary degeneration (HOD) is seen following lesions in the Guillain-Mollaret triangle. This is unique because the inferior olivary nucleus hypertrophies following degeneration unlike the typical atrophy seen in other structures. We report two cases of HOD in two different clinical scenarios. | 10.4103/2156-7514.150454 | 25,806,143 | Journal of clinical imaging science | 2,015 | ||
Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo. | Mycobacterium tuberculosis (Mtb) is thought to reside in macrophages, although infected dendritic cells (DCs) have been observed. Thus, although cellular associations have been made, global characterization of the cells harboring Mtb is lacking. We have performed temporal and quantitative characterization of the cells ... | 10.4049/jimmunol.179.4.2509 | 17,675,513 | D000818:Animals; D017951:Antigen Presentation; D001693:Biological Transport, Active; D015496:CD4-Positive T-Lymphocytes; D002465:Cell Movement; D054415:Chemokine CCL19; D054421:Chemokine CCL21; D019742:Chemokines, CC; D003713:Dendritic Cells; D049452:Green Fluorescent Proteins; D000949:Histocompatibility Antigens Class... | Journal of immunology (Baltimore, Md. : 1950) | 2,007 | C515461:Ccl19 protein, mouse; C515481:Ccl21b protein, mouse; D054415:Chemokine CCL19; D054421:Chemokine CCL21; D019742:Chemokines, CC; D000949:Histocompatibility Antigens Class II; D011948:Receptors, Antigen, T-Cell; D049452:Green Fluorescent Proteins |
The Current State of Cephalopod Science and Perspectives on the Most Critical Challenges Ahead From Three Early-Career Researchers. | Here, three researchers who have recently embarked on careers in cephalopod biology discuss the current state of the field and offer their hopes for the future. Seven major topics are explored: genetics, aquaculture, climate change, welfare, behavior, cognition, and neurobiology. Recent developments in each of these fi... | 10.3389/fphys.2018.00700 | 29,962,956 | Frontiers in physiology | 2,018 | ||
Micropatterned surfaces for reducing the risk of catheter-associated urinary tract infection: an in vitro study on the effect of sharklet micropatterned surfaces to inhibit bacterial colonization and migration of uropathogenic Escherichia coli. | BACKGROUND AND PURPOSE
Catheter-associated urinary tract infection (CAUTI) is the most common device-associated infection and can result in serious medical consequences. We studied the efficacy of a novel microscopic physical surface modification (Sharklet) for preventing bacterial colonization and migration of uropath... | 10.1089/end.2010.0611 | 21,819,223 | D000362:Agar; D015169:Colony Count, Microbial; D006801:Humans; D009068:Movement; D016459:Prosthesis-Related Infections; D012307:Risk Factors; D013499:Surface Properties; D014546:Urinary Catheterization; D014552:Urinary Tract Infections; D056689:Uropathogenic Escherichia coli | Journal of endourology | 2,011 | D000362:Agar |
Individualised Indications for Cytoreductive Nephrectomy: Which Criteria Define the Optimal Candidates? | CONTEXT
The current role of cytoreductive nephrectomy (CN) is controversial.
OBJECTIVE
Review of the available evidence about criteria defining CN optimal candidates.
EVIDENCE ACQUISITION
Collaborative critical narrative review of the literature focusing on CN oncological outcomes, perioperative morbidity, eligibil... | 10.1016/j.euo.2019.04.007 | 31,109,902 | D002292:Carcinoma, Renal Cell; D065426:Cytoreduction Surgical Procedures; D006801:Humans; D007680:Kidney Neoplasms; D009392:Nephrectomy; D016896:Treatment Outcome | European urology oncology | 2,019 | |
Does glutamine have a role in reducing infections in athletes? | There is an increased risk of infections in athletes undertaking prolonged, strenuous exercise. There is also some evidence that cells of the immune system are less able to mount a defence against infections after such exercise. The level of plasma glutamine, an important fuel for cells of the immune system, is decreas... | 10.1007/BF00334429 | 8,803,512 | D000328:Adult; D005260:Female; D005973:Glutamine; D006801:Humans; D007108:Immune Tolerance; D007239:Infections; D008297:Male; D010807:Physical Endurance; D010809:Physical Fitness; D012420:Running; D013177:Sports | European journal of applied physiology and occupational physiology | 1,996 | D005973:Glutamine |
On the HORYZON: moderated online social therapy for long-term recovery in first episode psychosis. | BACKGROUND
Early intervention services have demonstrated improved outcomes in first episode psychosis (FEP); however, recent evidence shows that treatment benefits may not be sustainable over time. These findings have resulted in repeated recommendations for the implementation of longer term treatment programs. An Inte... | 23,146,146 | D000293:Adolescent; D000328:Adult; D015928:Cognitive Behavioral Therapy; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010379:Peer Group; D010865:Pilot Projects; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders; D020127:Recovery of Function; D060756:Social Networking;... | Schizophrenia research | 2,013 | ||
Clinical outcomes of witnessed and monitored cases of in-hospital cardiac arrest in the general ward of a university hospital in Korea. | BACKGROUND
There are few studies of the epidemiology and clinical outcomes of patients with in-hospital cardiac arrest (IHCA) in a general hospital ward.
OBJECTIVE
To investigate the clinical outcomes of IHCA cases that occurred in the general ward of a university hospital and that were witnessed and/or monitored.
... | 10.4187/respcare.02448 | 23,611,868 | D016887:Cardiopulmonary Resuscitation; D005104:Expert Testimony; D005260:Female; D005500:Follow-Up Studies; D006323:Heart Arrest; D017052:Hospital Mortality; D006785:Hospitals, University; D006801:Humans; D015994:Incidence; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010... | Respiratory care | 2,013 | |
The Current Status of Peer Assessment Techniques and Sociometric Methods. | Current issues in the use of peer assessment techniques and sociometric methods are discussed. Attention is paid to the contributions of the four articles in this volume. Together these contributions point to the continual level of change and progress in these techniques. They also show that the paradigm underlying the... | 10.1002/cad.20209 | 28,892,288 | D006801:Humans; D010379:Peer Group; D012929:Psychological Distance; D012963:Sociometric Techniques | New directions for child and adolescent development | 2,017 | |
Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity. | PURPOSE
Doxorubicin is one of the most effective chemotherapeutic agents. However, up to 30% of the patients treated with doxorubicin suffer from congestive heart failure. The mechanism of doxorubicin cardiotoxicity is likely multifactorial and most importantly, the genetic factors predisposing to doxorubicin cardiotox... | 10.1158/1078-0432.CCR-13-3373 | 24,714,774 | D000818:Animals; D000903:Antibiotics, Antineoplastic; D015153:Blotting, Western; D066126:Cardiotoxicity; D004264:DNA Topoisomerases, Type I; D004272:DNA, Mitochondrial; D004317:Doxorubicin; D005455:Fluorescent Antibody Technique; D051379:Mice; D018345:Mice, Knockout; D008929:Mitochondria, Heart | Clinical cancer research : an official journal of the American Association for Cancer Research | 2,014 | D000903:Antibiotics, Antineoplastic; D004272:DNA, Mitochondrial; D004317:Doxorubicin; D004264:DNA Topoisomerases, Type I |
Prevalence of suicidal ideation and associated factors among HIV-positive MSM in Anhui, China. | The aim of this study was to investigate the prevalence and factors associated with suicidal ideation among HIV-positive men who have sex with men (MSM) in Anhui, China. A cross-sectional study was conducted to recruit HIV-positive MSM in Anhui, China. A total of 184 HIV-positive MSM gave informed consent and completed... | 10.1177/0956462414544722 | 25,060,699 | D000328:Adult; D001007:Anxiety; D002681:China; D003430:Cross-Sectional Studies; D003863:Depression; D015658:HIV Infections; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D012649:Self Concept; D012959:Socioeconomic Factors; D059020:Suici... | International journal of STD & AIDS | 2,015 | |
The fronto-parietal cortex of the prosimian Galago: patterns of cytochrome oxidase activity and motor maps. | We mapped the motor areas of the prosimian Galago crassicaudatus using intracortical electrical microstimulation and morphological and histochemical (cytochrome oxidase) techniques. Stimulation data showed that on the brain convexity there is an area (area Frontalis posterior, F post.) from which movements could be evo... | 10.1016/0166-4328(94)90067-1 | 8,185,856 | D000818:Animals; D001931:Brain Mapping; D004292:Dominance, Cerebral; D004558:Electric Stimulation; D003576:Electron Transport Complex IV; D005152:Facial Muscles; D005552:Forelimb; D005625:Frontal Lobe; D005701:Galago; D006614:Hindlimb; D009043:Motor Activity; D009044:Motor Cortex; D009055:Mouth; D009132:Muscles; D00947... | Behavioural brain research | 1,994 | D003576:Electron Transport Complex IV |
A method to find palindromes in nucleic acid sequences. | Various types of sequences in the human genome are known to play important roles in different aspects of genomic functioning. Among these sequences, palindromic nucleic acid sequences are one such type that have been studied in detail and found to influence a wide variety of genomic characteristics. For a nucleotide se... | 10.6026/97320630009255 | 23,515,654 | Bioinformation | 2,013 | ||
The complete mitochondrial genome of the Ctenophore Beroe cucumis, a mitochondrial genome showing rapid evolutionary rates. | We described the complete mitochondrial genome of the Ctenophore Beroe cucumis, which is a circular molecule of 10,487 bp in length. The new mitochondrial genome comprised only 12 genes, making it one of the smallest animals' mtDNA. Both nucleotide substitution and gene order rearrangements exhibited extreme high evolu... | 10.1080/23802359.2019.1580165 | 33,366,185 | Mitochondrial DNA. Part B, Resources | 2,019 | ||
New insights concerning the occurrence of fungi in water sources and their potential pathogenicity. | Fungi are known to occur ubiquitously in the environment. In the past years, the occurrence of filamentous fungi in the aquatic environment has been a subject of growing interest. This study describes the occurrence of various fungal genera in different drinking water sources being Penicillium and Trichoderma the most ... | 24,011,405 | D044822:Biodiversity; D005658:Fungi; D013172:Spores, Fungal; D013696:Temperature; D014871:Water Microbiology | Water research | 2,013 | ||
Phylogenetic analysis of PR genes in some pome fruit species with the emphasis on transcriptional analysis and ROS response under Erwinia amylovora inoculation in apple. | Attempts were made to identify eight pathogenesis related (PR) genes (i.e., PR-1a, PR3-ch1, PR3-Ch2, PR3-Ch3, PR3-Ch4, PR3-Ch5, PR-5 and PR-8) from 27 genotypes of apple, quince and pear, which are induced in response to inoculation with the pathogen Erwinia amylovora, the causal agent of fire blight. Totally, 32 PR ge... | 10.1007/s10709-015-9874-x | 26,589,211 | D018744:DNA, Plant; D060467:Disease Resistance; D044084:Erwinia amylovora; D005638:Fruit; D017343:Genes, Plant; D027845:Malus; D010802:Phylogeny; D010935:Plant Diseases; D010940:Plant Proteins; D031989:Pyrus; D017382:Reactive Oxygen Species; D027824:Rosaceae; D017422:Sequence Analysis, DNA | Genetica | 2,016 | D018744:DNA, Plant; D010940:Plant Proteins; D017382:Reactive Oxygen Species; C053376:pathogenesis-related proteins, plant |
The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway. | Polycomb group protein enhancer of zeste homolog 2 (EZH2) is a methyltransferase that correlates with the regulation of invasion and metastasis and is overexpressed in human cancers such as colorectal cancer. MicroRNA-31 (miR-31) plays an oncogenic role and is associated with BRAF mutation and poor prognosis in colorec... | 10.18632/oncotarget.7260 | 26,871,294 | D000230:Adenocarcinoma; D018256:Adenomatous Polyps; D000328:Adult; D000368:Aged; D003111:Colonic Polyps; D015179:Colorectal Neoplasms; D000071221:Enhancer of Zeste Homolog 2 Protein; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D035683:Micr... | Oncotarget | 2,016 | C534612:MIRN31 microRNA, human; D035683:MicroRNAs; C498409:EZH2 protein, human; D000071221:Enhancer of Zeste Homolog 2 Protein |
Atlas of computerized blood flow analysis in bone disease. | The role of computerized blood flow analysis in routine bone scanning is reviewed. Cases illustrating the technique include proven diagnoses of toxic synovitis, Legg-Perthes disease, arthritis, avascular necrosis of the hip, fractures, benign and malignant tumors, Paget's disease, cellulitis, osteomyelitis, and shin sp... | 10.1097/00003072-198311000-00017 | 6,653,012 | D000293:Adolescent; D000328:Adult; D000368:Aged; D001847:Bone Diseases; D001842:Bone and Bones; D002648:Child; D003201:Computers; D005269:Femur; D006615:Hip; D006801:Humans; D007866:Leg; D008875:Middle Aged; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D013977:Tibia | Clinical nuclear medicine | 1,983 | |
Iatrogenic Colonic Perforations: Changing the Paradigm. | PURPOSE
The purpose of our study was to investigate the clinical outcomes of colonoscopic perforations in patients.
MATERIALS AND METHODS
We retrospectively studied patients with perforations secondary to diagnostic/therapeutic colonoscopy between 2009 and 2015 at the Pontevedra Hospital Complex. We analyzed age, clo... | 10.1097/SLE.0000000000000610 | 30,608,917 | D000328:Adult; D000368:Aged; D003106:Colon; D003108:Colonic Diseases; D003113:Colonoscopy; D000072700:Conservative Treatment; D005215:Fasting; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D007416:Intestinal Perforation; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment O... | Surgical laparoscopy, endoscopy & percutaneous techniques | 2,019 | |
Thrombocytogenesis by megakaryocyte; Interpretation by protoplatelet hypothesis. | Serial transmission electron microscopy of human megakaryocytes (MKs) revealed their polyploidization and gradual maturation through consecutive transition in characteristics of various organelles and others. At the beginning of differentiation, MK with ploidy 32N, e.g., has 16 centrosomes in the cell center surrounded... | 10.2183/pjab.87.254 | 21,558,761 | D001792:Blood Platelets; D002454:Cell Differentiation; D002502:Centrioles; D006801:Humans; D008533:Megakaryocytes; D008954:Models, Biological; D011123:Polyploidy | Proceedings of the Japan Academy. Series B, Physical and biological sciences | 2,011 |
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