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Transient inter-cellular polymeric linker. | Three-dimensional (3D) tissue-engineered constructs with bio-mimicry cell-cell and cell-matrix interactions are useful in regenerative medicine. In cell-dense and matrix-poor tissues of the internal organs, cells support one another via cell-cell interactions, supplemented by small amount of the extra-cellular matrices... | 10.1016/j.biomaterials.2007.04.034 | 17,512,584 | D001672:Biocompatible Materials; D002448:Cell Adhesion; D002449:Cell Aggregation; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D003094:Collagen; D005109:Extracellular Matrix; D006801:Humans; D006909:Hydroxyproline; D007452:Iodates; D008855:Microscopy, Electron, Scanning; D015394:Molecular Structure; D011094:Po... | Biomaterials | 2,007 | D001672:Biocompatible Materials; D007452:Iodates; D011108:Polymers; D011094:Polyethyleneimine; D003094:Collagen; D006909:Hydroxyproline |
Inversion of Solvent Migration in Charged Membranes. | We theoretically demonstrate the possibility of inversion of solvent migration in charged membranes, opposing osmosis. Inversion of solvent migration is ascribed to the finite volume of ions in the solution permeating the membrane, a quantity that has been neglected in the literature so far. We propose a model of the e... | 10.1103/PhysRevLett.127.156001 | 34,678,022 | Physical review letters | 2,021 | ||
Primary observation of the role of posttranslational modification of dentin sialophosphoprotein (DSPP) on postnatal development of mandibular condyle in mice. | OBJECTIVES
We aimed to observe the posttranslational role of dentin sialophosphoprotein (DSPP) on postnatal development of mandibular condyle in mice.
METHODS
To explore the function of full-length DSPP, four groups of mice were employed: (1) wild type (WT) mice; (2)Dspp knockout (Dspp KO) mice; (3) mice expressing t... | 10.1016/j.archoralbio.2021.105086 | 33,639,479 | D000818:Animals; D003804:Dentin; D016326:Extracellular Matrix Proteins; D008335:Mandibular Condyle; D051379:Mice; D018345:Mice, Knockout; D010750:Phosphoproteins; D011499:Protein Processing, Post-Translational; D012795:Sialoglycoproteins; D055114:X-Ray Microtomography | Archives of oral biology | 2,021 | D016326:Extracellular Matrix Proteins; D010750:Phosphoproteins; D012795:Sialoglycoproteins; C407547:dentin sialophosphoprotein |
A Meta-Learning Approach for Few-Shot Face Forgery Segmentation and Classification. | The technology for detecting forged images is good at detecting known forgery methods. It trains neural networks using many original and corresponding forged images created with known methods. However, when encountering unseen forgery methods, the technology performs poorly. Recently, one suggested approach to tackle t... | 10.3390/s23073647 | 37,050,708 | Sensors (Basel, Switzerland) | 2,023 | ||
Vitamin B6 (pyridoxine) and its derivatives are efficient singlet oxygen quenchers and potential fungal antioxidants. | Vitamin B6 (pyridoxine, 1) and its derivatives: pyridoxal (2), pyridoxal 5-phosphate (3) and pyridoxamine (4) are important natural compounds involved in numerous biological functions. Pyridoxine appears to play a role in the resistance of the filamentous fungus Cercospora nicotianae to its own abundantly produced stro... | 10.1562/0031-8655(2000)071<0129:sipvbp>2.0.co;2 | 10,687,384 | D001203:Ascomycota; D007700:Kinetics; D010084:Oxidation-Reduction; D010100:Oxygen; D010569:Perylene; D010777:Photochemistry; D011730:Pyridoxal; D011732:Pyridoxal Phosphate; D011733:Pyridoxamine; D011736:Pyridoxine; D026082:Singlet Oxygen; D014466:Ultraviolet Rays | Photochemistry and photobiology | 2,000 | D026082:Singlet Oxygen; D011730:Pyridoxal; D010569:Perylene; D011732:Pyridoxal Phosphate; D011733:Pyridoxamine; C026363:cercosporin; D011736:Pyridoxine; D010100:Oxygen |
A catecholaminergic sensory neuron phenotype in cranial derivatives of the neural crest: regulation by cell aggregation and nerve growth factor. | Tyrosine hydroxylase (TH) is transiently detectable in cells distributed throughout cranial sensory ganglia during early stages of gangliogenesis [embryonic day (E) 10.5-15.5]. Although TH cells appear in embryonic ganglia of both neural crest and placode origin, mature cranial sensory neurons that express catecholamin... | 1,683,903 | D000818:Animals; D000831:Animals, Newborn; D002395:Catecholamines; D002449:Cell Aggregation; D003391:Cranial Nerves; D005724:Ganglia; D009414:Nerve Growth Factors; D009432:Neural Crest; D009475:Neurons, Afferent; D010641:Phenotype; D051381:Rats; D014446:Tyrosine 3-Monooxygenase | The Journal of neuroscience : the official journal of the Society for Neuroscience | 1,991 | D002395:Catecholamines; D009414:Nerve Growth Factors; D014446:Tyrosine 3-Monooxygenase | |
Comparison of different activity parameters in atopic dermatitis: correlation with clinical scores. | BACKGROUND
Several laboratory markers have been described to correlate positively with disease activity of atopic dermatitis (AD). These include soluble adhesion molecules and eosinophil granular proteins. Although the correlation of these parameters with the severity and extent of skin involvement has been repeatedly ... | 10.1046/j.1365-2133.2002.04938.x | 12,410,700 | D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D001798:Blood Proteins; D003876:Dermatitis, Atopic; D019040:E-Selectin; D047091:Eosinophil Granule Proteins; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D017942:Nitric Acid; D011537:Pruritus; D012260:Ribonucleases; D012720:Severity of I... | The British journal of dermatology | 2,002 | D015415:Biomarkers; D001798:Blood Proteins; D019040:E-Selectin; D047091:Eosinophil Granule Proteins; D019010:Vascular Cell Adhesion Molecule-1; D017942:Nitric Acid; D012260:Ribonucleases |
Patients' perspectives on how idiopathic pulmonary fibrosis affects the quality of their lives. | BACKGROUND
Idiopathic pulmonary fibrosis (IPF) is a debilitating lung disease with a survival of only three to five years from the time of diagnosis. Due to a paucity of studies, large gaps remain in our understanding of how IPF affects the quality of patients' lives. In only one other study did investigators ask patie... | 10.1186/1477-7525-3-61 | 16,212,668 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health; D002140:California; D015897:Comorbidity; D018450:Disease Progression; D005260:Female; D017144:Focus Groups; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011658:Pulmonary Fi... | Health and quality of life outcomes | 2,005 | |
Putative regulation of expression of members of the Ets variant 4 transcription factor family and their downstream targets in the rat epididymis. | Several genes expressed in the initial segment of the epididymis depend on factors from the testis that reach the epididymis via the luminal system. These include gamma-glutamyl transpeptidase mRNA IV (Ggt_pr4), steroid 5 alpha reductase (Srd5a1), glutathione peroxidase 5 (Gpx5), and cystatin-related epididymal spermat... | 10.1095/biolreprod.105.044354 | 16,394,217 | D000818:Animals; D004268:DNA-Binding Proteins; D004822:Epididymis; D005786:Gene Expression Regulation; D007150:Immunohistochemistry; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013737:Testis; D013997:Time Factors; D015534:Trans-Activators; D014157:Transcription Factors | Biology of reproduction | 2,006 | D004268:DNA-Binding Proteins; C510952:ETV1 protein, rat; C510951:ETV4 protein, rat; C513243:Etv5 protein, rat; D015534:Trans-Activators; D014157:Transcription Factors |
Outcomes of aortic coarctation surgical treatment in adults. | OBJECTIVE
The aim of this study is to describe our experience in aortic coarctation surgery in adult patients by assessing the immediate and mid-term outcomes.
METHODS
From January 1987 to March 2000, 50 consecutive adult patients underwent surgery for correction of aortic coarctation, through left lateral thoracotom... | 20,011,882 | D000293:Adolescent; D000328:Adult; D001017:Aortic Coarctation; D006348:Cardiac Surgical Procedures; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011300:Preoperative Care; D016896:Treatment Outcome; D055815:Young Adult | Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular | 2,009 | ||
Chitosan-Salicylic acid and Zinc sulphate nano-formulations defend against yellow rust in wheat by activating pathogenesis-related genes and enzymes. | Stripe rust instigated by Puccinia striiformis f. sp. tritici causes major yield loss in wheat. In this study, disease resistance was induced in wheat by pre-activation of pathogenesis related (PR) genes using two different nano-formulations (NFs) i.e. Chitosan- Salicylic acid (SA) NFs (CH-NFs) and Zinc sulphate NFs (Z... | 10.1016/j.plaphy.2022.10.002 | 36,228,444 | Plant physiology and biochemistry : PPB | 2,022 | ||
Platelet biology and response to antiplatelet therapy in women: implications for the development and use of antiplatelet pharmacotherapies for cardiovascular disease. | Women are underrepresented in cardiovascular studies, even as their preponderance in the aging population steadily increases. Although concerns have been raised about the differential benefit of antiplatelet medications for women, the propensity for increased bleeding among women has also been recognized. A better unde... | 10.1016/j.jacc.2011.09.075 | 22,381,424 | D001792:Blood Platelets; D002318:Cardiovascular Diseases; D015507:Drugs, Investigational; D005260:Female; D006801:Humans; D010975:Platelet Aggregation Inhibitors | Journal of the American College of Cardiology | 2,012 | D015507:Drugs, Investigational; D010975:Platelet Aggregation Inhibitors |
Effects of acetylcholine on sling and clasp fibers of the human lower esophageal sphincter. | BACKGROUND AND AIM
Manometric studies on the human lower esophageal sphincter (LES) have shown radial asymmetry of the high-pressure zone (HPZ). The aim of this study was to compare the functional properties of human LES clasp and sling muscles, and to look at their relationship with the expression of muscarinic recept... | 10.1111/j.1440-1746.2011.06731.x | 21,443,668 | D000109:Acetylcholine; D000368:Aged; D015153:Blotting, Western; D002118:Calcium; D002121:Calcium Channel Blockers; D018679:Cholinergic Agonists; D004305:Dose-Response Relationship, Drug; D049630:Esophageal Sphincter, Lower; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D018613:Microscopy, C... | Journal of gastroenterology and hepatology | 2,011 | D002121:Calcium Channel Blockers; D018679:Cholinergic Agonists; D012333:RNA, Messenger; D011976:Receptors, Muscarinic; D009543:Nifedipine; D000109:Acetylcholine; D002118:Calcium |
Hepatocellular carcinoma: systemic therapies and future perspectives. | Hepatocellular carcinoma is (HCC) the most common primary malignancy of the liver in adults. It is also the fifth most common solid cancer worldwide and the third leading cause of cancer-related deaths. Treatment options for HCC include liver transplantation, surgical resection, locoregional therapies and chemotherapy.... | 10.1586/14737140.2014.949246 | 25,199,765 | D000328:Adult; D006528:Carcinoma, Hepatocellular; D006526:Hepatitis C; D006801:Humans; D007167:Immunotherapy; D008103:Liver Cirrhosis; D008113:Liver Neoplasms; D016031:Liver Transplantation; D058990:Molecular Targeted Therapy; D009765:Obesity; D015996:Survival Rate | Expert review of anticancer therapy | 2,014 | |
Better and Worse: A Dual-Process Model of the Relationship between Core Self-evaluation and Work-Family Conflict. | Based on both resource allocation theory (Becker, 1965; Bergeron, 2007) and role theory (Katz and Kahn, 1978), the current study aims to uncover the relationship between core self-evaluation (CSE) and three dimensions of work interference with family (WIF). A dual-process model was proposed, in which both work stress a... | 10.3389/fpsyg.2016.01579 | 27,790,177 | Frontiers in psychology | 2,016 | ||
Rituximab for treatment-refractory pemphigus and pemphigoid: a case series of 17 patients. | BACKGROUND
Rituximab has been increasingly used in autoimmune blistering dermatoses, mainly in pemphigus. However, only a few larger case series are available on this subject and information on the efficacy of retreatment with rituximab during relapses is lacking.
OBJECTIVE
We sought to determine efficacy and adverse... | 10.1016/j.jaad.2010.07.032 | 21,641,080 | D000328:Adult; D000368:Aged; D058846:Antibodies, Monoclonal, Murine-Derived; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007155:Immunologic Factors; D007166:Immunosuppressive Agents; D008297:Male; D008875:Middle Aged; D010391:Pemphigoid, Bullous; D010392:Pemphigus; D000069283:Rituximab | Journal of the American Academy of Dermatology | 2,011 | D058846:Antibodies, Monoclonal, Murine-Derived; D007155:Immunologic Factors; D007166:Immunosuppressive Agents; D000069283:Rituximab |
Effects of behavioral change techniques on diet and physical activity in colorectal cancer patients: a systematic review and meta-analysis. | PURPOSE
To investigate the effect of behavior change technology on diet, exercise, and sedentary behaviors in colorectal cancer over the last decade.
METHODS
This study systematically searched six English databases (Cochrane Library, EMBASE, APA PsycInfo, SCOPUS, PubMed, Web of Science) and three Chinese databases (C... | 10.1007/s00520-022-07511-7 | 36,515,770 | D006801:Humans; D015444:Exercise; D004032:Diet; D057185:Sedentary Behavior; D015438:Health Behavior; D015179:Colorectal Neoplasms | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer | 2,022 | |
Sulfate template induced S/O doped carbon nanosheets enabling rich physi/chemi-sorption sites for high-performance zinc ion hybrid capacitors. | Zinc ion hybrid capacitors (ZIHCs) are encouraging energy storage devices for large-scale applications. Nevertheless, the electrochemical performance of ZIHCs is often limited by the cathode materials which show low energy density and rate capability practically. One of the efficient strategies to overcome these challe... | 10.1016/j.jcis.2023.08.110 | 37,611,468 | Journal of colloid and interface science | 2,023 | ||
Carnosic acid reduces cytokine-induced adhesion molecules expression and monocyte adhesion to endothelial cells. | BACKGROUND
Expression of cell adhesion molecules on the endothelium and the attachment of monocytes to endothelium may play a major role in the early atherogenic process.
AIM OF THE STUDY
We investigated the effects of carnosic acid on the adhesion of U937 cells to IL-1beta-treated human umbilical vein endothelial ce... | 10.1007/s00394-008-0768-x | 19,142,568 | D045784:Abietanes; D002448:Cell Adhesion; D015815:Cell Adhesion Molecules; D002470:Cell Survival; D019040:E-Selectin; D042783:Endothelial Cells; D006801:Humans; D018799:Intercellular Adhesion Molecule-1; D053583:Interleukin-1beta; D009000:Monocytes; D016328:NF-kappa B; D010936:Plant Extracts; D017382:Reactive Oxygen Sp... | European journal of nutrition | 2,009 | D045784:Abietanes; D015815:Cell Adhesion Molecules; D019040:E-Selectin; D053583:Interleukin-1beta; D016328:NF-kappa B; D010936:Plant Extracts; D017382:Reactive Oxygen Species; D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1; C018381:salvin |
No relationship between baseline salivary alpha-amylase and State-Trait Anxiety Inventory Score in drug-naïve patients with short-illness-duration first episode major depressive disorder: An exploratory study. | BACKGROUND
Salivary α-amylase (sAA) activity alternations are observed in major depressive disorder (MDD) being associated with depression severity and its specific psychopathological dimensions with anxiety being attributed to distress. No data is available on sAA in MDD according to Hamilton Rating Scale for Depressi... | 10.4317/jced.53631 | 28,469,817 | Journal of clinical and experimental dentistry | 2,017 | ||
Prognostic value of endothelial biomarkers in refractory cardiogenic shock with ECLS: a prospective monocentric study. | BACKGROUND
Extracorporeal membrane oxygenation (ECMO) is often used in critical patients with severe myocardial failure. However, the mortality rate of patients on ECMO is often high. Recent studies have suggested that endothelial activation with subsequent vascular barrier breakdown is a critical pathogenic mechanism ... | 10.1186/s12871-019-0747-1 | 31,092,199 | D000328:Adult; D000368:Aged; D015415:Biomarkers; D004730:Endothelium, Vascular; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012770:Shock, Cardiogenic; D042461:Vascular Endothelial Growth Factor A; D03392... | BMC anesthesiology | 2,019 | D015415:Biomarkers; C467484:VEGFA protein, human; C555023:VPS51 protein, human; D042461:Vascular Endothelial Growth Factor A; D033921:Vesicular Transport Proteins |
Computerized assessment of pulmonary fissure integrity using high resolution CT. | PURPOSE
Knowledge of pulmonary interlobar fissure integrity is of interest in a number of clinical and investigational applications. The authors developed and tested a high resolution CT based automated computerized scheme for this purpose.
METHODS
The fissure integrity assessment scheme consists of the following ste... | 10.1118/1.3475937 | 20,964,185 | D006801:Humans; D008171:Lung Diseases; D015588:Observer Variation; D014057:Tomography, X-Ray Computed | Medical physics | 2,010 | |
Surface treatments on CAD/CAM glass-ceramics: Influence on roughness, topography, and bond strength. | OBJECTIVE
To evaluate the influence of surface treatment on roughness (SA), topography, and shear bond strength (SBS) of computer-aided designer and manufacture (CAD/CAM) zirconia-reinforced lithium silicate (ZLS) and feldspathic (FEL) glass-ceramics.
MATERIALS AND METHODS
FEL and ZLS specimens were submitted to 5% o... | 10.1111/jerd.12734 | 33,991,436 | D002516:Ceramics; D003201:Computers; D001840:Dental Bonding; D003776:Dental Porcelain; D008422:Materials Testing; D019279:Resin Cements; D013499:Surface Properties | Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] | 2,021 | D019279:Resin Cements; D003776:Dental Porcelain |
Correlation of serum antibody titer for avian encephalomyelitis virus (AEV) in hens with the resistance of progeny embryos to AEV. | Serum antibody titers for avian encephalomyelitis virus of vaccinated breeding hens were correlated with the resistance of the hens' progeny embryos to viral challenge. All of the embryos from hens that had enzyme-linked immunosorbent assay titers greater than 400 were resistant to challenge, and two-thirds of the embr... | 3,000,340 | D000818:Animals; D000914:Antibodies, Viral; D002642:Chick Embryo; D002645:Chickens; D001350:Encephalomyelitis Virus, Avian; D004770:Enterovirus; D004769:Enterovirus Infections; D005260:Female; D007109:Immunity | Avian diseases | 1,985 | D000914:Antibodies, Viral | |
Human immunodeficiency virus: quantifying the risk of transmission of HIV to dental health care workers. | The potential for the increased risk of transmission of HIV (Human Immunodeficiency Virus) from patients to dental health care workers (DHCWs) in the workplace is examined. Based on published and hypothetical risk estimates, the authors conclude that in certain world communities with high prevalence rates of HIV infect... | 10.1111/j.1600-0528.1990.tb00083.x | 2,090,380 | D000163:Acquired Immunodeficiency Syndrome; D003727:Dental Auxiliaries; D003815:Dentists; D004198:Disease Susceptibility; D015658:HIV Infections; D006679:HIV Seropositivity; D006801:Humans; D015994:Incidence; D009784:Occupational Diseases; D015995:Prevalence; D011336:Probability; D012307:Risk Factors; D014481:United St... | Community dentistry and oral epidemiology | 1,990 | |
Pathophysiology of slow vertical saccades in progressive supranuclear palsy. | OBJECTIVES
To investigate the relative roles of burst neurons (which generate the saccadic command) and omnipause neurons (which gate the activity of burst neurons) in the pathogenesis of slow saccades in progressive supranuclear palsy (PSP).
BACKGROUND
Experimental inactivation of mesencephalic burst neurons impairs... | 10.1212/wnl.57.11.2070 | 11,739,828 | D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009474:Neurons; D020734:Parkinsonian Disorders; D011149:Pons; D012154:Reticular Formation; D012438:Saccades; D013494:Supranuclear Palsy, Progressive | Neurology | 2,001 | |
[The Value of Ultrasonography Compared with Magnetic Resonance Imaging in the Diagnosis of Deltoid Ligament Injuries--Is there a Difference?]. | BACKGROUND
Ruptures of the deltoid ligament can lead to ankle instability which may cause arthrosis. Aim of this comparative clinical trial was to assess the value of ultrasonography (US) compared to magnetic resonance imaging (MRI) in the diagnosis of medial collateral (deltoid) ligament ruptures associated with Weber... | 10.1055/s-0035-1545988 | 26,016,524 | D000293:Adolescent; D000328:Adult; D016512:Ankle Injuries; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D017844:Lateral Ligament, Ankle; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012421:Rupture; D012680:Sensitivity and Specificity; D0... | Zeitschrift fur Orthopadie und Unfallchirurgie | 2,015 | |
Impact of traditional Samoan lifestyle (fa'aSamoa) on cancer screening practices. | BACKGROUND
The Samoan way of life, or the fa'aSamoa, is a collection of practices and rituals by which Samoans conduct their lives. The purpose of this study was to explore the possible influence of the fa'aSamoa on cancer prevention practices.
METHODS
The investigators conducted six focus groups; three in Carson, Ca... | 10.1016/j.cdp.2007.04.012 | 18,342,455 | D003466:Cultural Characteristics; D017144:Focus Groups; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008019:Life Style; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009369:Neoplasms; D018947:Samoa | Cancer detection and prevention | 2,008 | |
Albert Ochsner, MD: Chicago Surgeon and Mentor to Alton Ochsner. | Albert John Ochsner was a member of a select group of medical practitioners who made their impact on medical practice and surgical techniques. He was a pioneer in microscopy and made numerous contributions to the medical literature, on topics ranging from the organization of hospitals and advances in the treatment of h... | 21,765,742 | Ochsner journal | 2,001 | |||
A multivariate time-frequency approach for tracking QT variability changes unrelated to heart rate variability. | The beat-to-beat variability of the QT interval (QTV) is a marker of ventricular repolarization (VR) dynamics and it has been suggested as an index of sympathetic ventricular outflow and cardiac instability. However, QTV is also affected by RR (or heart rate) variability (RRV), and QTV due to RRV may reduce QTV specifi... | 10.1109/EMBC.2016.7590852 | 28,268,475 | D000328:Adult; D000465:Algorithms; D004562:Electrocardiography; D064368:Healthy Volunteers; D006339:Heart Rate; D006801:Humans; D008955:Models, Cardiovascular; D015999:Multivariate Analysis; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D018667:Tilt-Table Test | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 2,016 | |
Targeted somatic mutagenesis through CRISPR/Cas9 ribonucleoprotein complexes in the olive fruit fly, Bactrocera oleae. | The olive fruit fly, Bactrocera oleae (Diptera: Tephritidae), is the most destructive insect pest of olive cultivation, causing significant economic and production losses. Here, we present the establishment of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 methodology for gene disruption in... | 10.1002/arch.21667 | 32,100,335 | D000818:Animals; D064113:CRISPR-Cas Systems; D000072669:Gene Editing; D019476:Insect Proteins; D016296:Mutagenesis; D012261:Ribonucleoproteins; D033621:Tephritidae | Archives of insect biochemistry and physiology | 2,020 | D019476:Insect Proteins; D012261:Ribonucleoproteins |
Implications of a mental health intervention for elderly mentally ill residents of residential care facilities. | Unresolved issues of responsibility between mental health and aging systems low priority within the mental health system for serving older RCF residents, and little expectation for the facility to be a treatment environment, all contribute to gaps in service delivery to mentally ill boarding home residents. This articl... | 10.2190/MXAQ-XKWT-BD4R-0EBT | 1,905,681 | D000203:Activities of Daily Living; D000223:Adaptation, Psychological; D000368:Aged; D003156:Community Mental Health Services; D003258:Consumer Behavior; D003688:Deinstitutionalization; D005260:Female; D016352:Group Homes; D006301:Health Services Needs and Demand; D006707:Homes for the Aged; D006801:Humans; D008134:Lon... | International journal of aging & human development | 1,991 | |
Diabetes camp still matters: Relationships with diabetes-specific distress, strengths, and self-care skills. | OBJECTIVE
Prior studies suggest diabetes camps improve psychosocial well-being in youth with type 1 diabetes but these studies suffer from variable levels of rigor. The present study assessed associations between camp participation and diabetes distress, perceived independence in diabetes self-care, and diabetes streng... | 10.1111/pedi.12836 | 30,793,473 | D000223:Adaptation, Psychological; D000293:Adolescent; D001294:Attitude to Health; D002165:Camping; D002648:Child; D003922:Diabetes Mellitus, Type 1; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D010379:Peer Group; D010465:Perception; D012648:Self Care; D020377:Self Efficacy; D013315:Stres... | Pediatric diabetes | 2,019 | |
Work of breathing as a tool to diagnose severe fixed upper airway obstruction. | A 4-year-old girl with bilateral vocal fold palsy was successfully decannulated from tracheotomy after seven laryngeal procedures. But an important stridor and dyspnea recurred 13 months after decannulation. Nocturnal gas exchange was normal but her daytime work of breathing was increased by fourfold, without any benef... | 10.1002/ppul.22772 | 23,401,484 | D000402:Airway Obstruction; D002675:Child, Preschool; D045422:Continuous Positive Airway Pressure; D004417:Dyspnea; D005260:Female; D006801:Humans; D007829:Laryngostenosis; D011183:Postoperative Complications; D012135:Respiratory Sounds; D014140:Tracheotomy; D014826:Vocal Cord Paralysis; D014939:Work of Breathing | Pediatric pulmonology | 2,014 | |
How the past becomes the past: The temporal positioning of collective memory. | Recognizing that the past does not necessarily pass of its own accord but rather is made to pass is crucial for understanding relationships between collective memory, temporality and the past. Analyzing processes of temporal negotiation reveals that changing the ending (or, in some cases creating one at all) requires r... | 10.1111/1468-4446.12881 | 34,350,979 | The British journal of sociology | 2,021 | ||
Lipoprotein-dependent and -independent immune responses to spirochetal infection. | In this study, we used the epidermal suction blister technique, in conjunction with multiparameter flow cytometry, to analyze the cellular and cytokine responses elicited by intradermal injection of human volunteers with synthetic analogs for spirochetal lipoproteins and compared the responses to findings previously re... | 10.1128/CDLI.12.8.949-958.2005 | 16,085,913 | D000293:Adolescent; D000328:Adult; D000368:Aged; D001425:Bacterial Outer Membrane Proteins; D015748:Borrelia burgdorferi Group; D016207:Cytokines; D003713:Dendritic Cells; D005260:Female; D006801:Humans; D008074:Lipoproteins; D008297:Male; D008875:Middle Aged; D009000:Monocytes; D012882:Skin Tests; D013145:Spirochaetal... | Clinical and diagnostic laboratory immunology | 2,005 | D001425:Bacterial Outer Membrane Proteins; D016207:Cytokines; D008074:Lipoproteins |
Novel design of interactive multimodal biofeedback system for neurorehabilitation. | A previous design of a biofeedback system for Neurorehabilitation in an interactive multimodal environment has demonstrated the potential of engaging stroke patients in task-oriented neuromotor rehabilitation. This report explores the new concept and alternative designs of multimedia based biofeedback systems. In this ... | 10.1109/IEMBS.2006.260409 | 17,947,122 | D000465:Algorithms; D001132:Arm; D001676:Biofeedback, Psychology; D003198:Computer Simulation; D003201:Computers; D004867:Equipment Design; D006801:Humans; D009068:Movement; D009146:Music; D009422:Nervous System Diseases; D011597:Psychomotor Performance; D012984:Software; D013016:Sound; D014584:User-Computer Interface;... | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference | 2,006 | |
Abdominal Tuberculosis: Experience from Two Tertiary-Care Hospitals in the Paris Region. | Abdominal tuberculosis (ATB) is uncommon and not very well known by clinicians. We describe the characteristics, evolution, and treatment of patients with ATB in two large hospitals in the Paris region. We reviewed all records of patients treated for ATB, from January 01, 2010 to December 01, 2016, diagnosed by bacteri... | 33,205,739 | D000005:Abdomen; D015746:Abdominal Pain; D000328:Adult; D000995:Antitubercular Agents; D003937:Diagnosis, Differential; D054242:Emigrants and Immigrants; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010297:Paris; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D014376:Tuberculosis | The American journal of tropical medicine and hygiene | 2,021 | D000995:Antitubercular Agents | |
Interleukin-10: A Compelling Therapeutic Target in Patients With Irritable Bowel Syndrome. | PURPOSE
Pro- and antiinflammatory cytokines are important modulators of the immune response and play a major role in conditions of intestinal inflammation, such as irritable bowel syndrome (IBS). Cytokine production is regulated genetically, and imbalances in cytokine secretion may affect disease susceptibility and cli... | 10.1016/j.clinthera.2017.01.030 | 28,237,672 | D001007:Anxiety; D016207:Cytokines; D003863:Depression; D006801:Humans; D007249:Inflammation; D016753:Interleukin-10; D043183:Irritable Bowel Syndrome | Clinical therapeutics | 2,017 | D016207:Cytokines; C508609:IL10 protein, human; D016753:Interleukin-10 |
Autoimmune intervention by CD154 blockade prevents T cell retention and effector function in the target organ. | The CD40-CD154 interaction is an attractive target for therapeutic intervention in many autoimmune disorders, including multiple sclerosis. Previously, we showed that CD154 blockade both inhibited the onset of experimental autoimmune encephalomyelitis and blocked clinical disease progression (relapses) in mice with est... | 10.4049/jimmunol.166.3.1547 | 11,160,195 | D019264:Adoptive Transfer; D000595:Amino Acid Sequence; D000818:Animals; D019138:Antibodies, Blocking; D001324:Autoantigens; D019013:CD40 Antigens; D023201:CD40 Ligand; D002465:Cell Movement; D016207:Cytokines; D004681:Encephalomyelitis, Autoimmune, Experimental; D018984:Epitopes, T-Lymphocyte; D005260:Female; D007106:... | Journal of immunology (Baltimore, Md. : 1950) | 2,001 | D019138:Antibodies, Blocking; D001324:Autoantigens; D019013:CD40 Antigens; D016207:Cytokines; D018984:Epitopes, T-Lymphocyte; D007106:Immune Sera; D007166:Immunosuppressive Agents; C111390:OVA 323-339; D010446:Peptide Fragments; D023201:CD40 Ligand; D010047:Ovalbumin |
Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1. | HER4 expression in human breast cancers correlates with a positive prognosis. While heregulin inhibits the growth of HER4-positive breast cancer cells, it does so by undefined mechanisms. We demonstrate that heregulin-induced HER4 activity inhibits cell proliferation and delays G(2)/M progression of breast cancer cells... | 10.1128/MCB.01950-05 | 16,914,727 | D000818:Animals; D019313:BRCA1 Protein; D001943:Breast Neoplasms; D004847:Epithelial Cells; D066246:ErbB Receptors; D005091:Exons; D016195:G2 Phase; D015972:Gene Expression Regulation, Neoplastic; D006367:HeLa Cells; D006801:Humans; D008321:Mammary Glands, Animal; D051379:Mice; D048055:Mitogen-Activated Protein Kinase ... | Molecular and cellular biology | 2,006 | D019313:BRCA1 Protein; D020890:Neuregulin-1; D012333:RNA, Messenger; D048056:Mitogen-Activated Protein Kinase 9; C587689:ERBB4 protein, human; D066246:ErbB Receptors; C587690:Erbb4 protein, mouse; D018719:Receptor, ErbB-2; D066247:Receptor, ErbB-4; D048055:Mitogen-Activated Protein Kinase 8 |
A multi-institutional retrospective study of hyperthermic plus intravesical chemotherapy versus intravesical chemotherapy treatment alone in intermediate and high risk nonmuscle-invasive bladder cancer. | Objective
To compare the efficacy and safety of hyperthermic intravesical chemotherapy (HIVEC) and intravesical chemotherapy (IVEC) in patients with intermediate and high risk nonmuscle-invasive bladder cancer (NMIBC) after transurethral resection.
Methods
We included 560 patients diagnosed with primary or recurrent ... | 10.20892/j.issn.2095-3941.2020.0125 | 33,628,603 | D000283:Administration, Intravesical; D000368:Aged; D000970:Antineoplastic Agents; D002681:China; D003131:Combined Modality Therapy; D015653:Cystectomy; D016208:Databases, Factual; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Su... | Cancer biology & medicine | 2,021 | D000970:Antineoplastic Agents |
The impact of second-hand tobacco smoke exposure on pregnancy outcomes, infant health, and the threat of third-hand smoke exposure to our environment and to our children. | Smoking during pregnancy is associated with various adverse effects on pregnancy and fetal development, carries a lot of serious complications such as spontaneous abortion, placental abruption, and reduced birth weight of the newborn. Children of smoking mothers have an increased risk of premature birth, low birth weig... | 23,421,018 | D000022:Abortion, Spontaneous; D001249:Asthma; D004781:Environmental Exposure; D005062:European Union; D005260:Female; D047109:Fetal Development; D006293:Health Promotion; D006801:Humans; D007229:Infant Welfare; D007231:Infant, Newborn; D009538:Nicotine; D011247:Pregnancy; D011256:Pregnancy Outcome; D011297:Prenatal Ex... | Przeglad lekarski | 2,012 | D014028:Tobacco Smoke Pollution; D009538:Nicotine | |
Quantitative imaging of tissue sections using infrared scanning technology. | Quantification of immunohistochemically (IHC) labelled tissue sections typically yields semi-quantitative results. Visualising infrared (IR) 'tags', with an appropriate scanner, provides an alternative system where the linear nature of the IR fluorophore emittance enables realistic quantitative fluorescence IHC (QFIHC)... | 10.1111/joa.12398 | 26,510,706 | D000818:Animals; D001921:Brain; D007091:Image Processing, Computer-Assisted; D007150:Immunohistochemistry; D007259:Infrared Rays; D051379:Mice; D008807:Mice, Inbred BALB C; D008853:Microscopy; D023421:Models, Animal | Journal of anatomy | 2,016 | |
Esophageal diverticula: from diagnosis to therapeutic management-narrative review. | Background and Objective
Esophageal diverticulum (ED) is a relatively rare condition, characterized by high etio- and pathophysiological versatility, with an uncommon clinical impact, consequently requiring a complete and complex diagnostic evaluation, so that the therapeutic decision is "appropriate" to a specific cas... | 10.21037/jtd-22-861 | 36,910,058 | Journal of thoracic disease | 2,023 | ||
Efficient excision of the upstream large intron from P4-generated pre-mRNA of the parvovirus minute virus of mice requires at least one donor and the 3' splice site of the small downstream intron. | We have previously shown that efficient excision of the upstream large intron from P4-generated pre-mRNA of the autonomous parvovirus minute virus of mice depends upon at least the initial presence of sequences within the downstream small intron (Q. Zhao, R. V. Schoborg, and D. J. Pintel, J. Virol. 68:2849-2859, 1994).... | 10.1128/JVI.69.10.6170-6179.1995 | 7,666,519 | D000818:Animals; D001483:Base Sequence; D005809:Genes, Regulator; D005814:Genes, Viral; D007438:Introns; D007739:L Cells; D051379:Mice; D008915:Minute Virus of Mice; D008969:Molecular Sequence Data; D016296:Mutagenesis; D009838:Oligodeoxyribonucleotides; D012322:RNA Precursors; D012326:RNA Splicing; D012367:RNA, Viral;... | Journal of virology | 1,995 | D009838:Oligodeoxyribonucleotides; D012322:RNA Precursors; D012367:RNA, Viral |
Autocrine/paracrine role of the angiopoietin-1 and -2/Tie2 system in cell proliferation and chemotaxis of cultured fibroblastic synoviocytes in rheumatoid arthritis. | Hypervascularity is a characteristic synovial feature of rheumatoid arthritis (RA). We previously reported that Tie1 and Tie2, endothelium-specific tyrosine kinase receptors essential for angiogenesis, are expressed not only by vascular cells, but also by a subpopulation of synovial lining and stromal cells in the infl... | 10.1016/j.humpath.2003.11.010 | 14,991,531 | D000328:Adult; D000368:Aged; D042683:Angiopoietin-1; D042702:Angiopoietin-2; D001172:Arthritis, Rheumatoid; D002455:Cell Division; D002478:Cells, Cultured; D002633:Chemotaxis; D005260:Female; D005347:Fibroblasts; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D008297:Male; D008875:Middle A... | Human pathology | 2,004 | D042683:Angiopoietin-1; D042702:Angiopoietin-2; D042787:Receptor, TIE-2 |
Options for determination of 2-D distribution of collagen fibrils in transmission electron micrographs--application to the mammalian corneal stroma. | AIMS
To assess methods for both measurement of and comparison between fibril spacing arrangement in transmission electron micrograph (TEM) images of collagen fibrils.
METHODS
Rabbit corneas were glutaraldhyde fixed, treated with osmium tetroxide and then thin sections stained with aqueous phosphotungstic acid. TEM im... | 10.1002/jemt.20890 | 20,564,523 | D000818:Animals; D003094:Collagen; D003319:Corneal Stroma; D007091:Image Processing, Computer-Assisted; D046529:Microscopy, Electron, Transmission; D011817:Rabbits | Microscopy research and technique | 2,011 | D003094:Collagen |
Lipase-catalyzed synthesis of starch palmitate in mixed ionic liquids. | Lipase-catalyzed synthesis of starch palmitate was investigated in ionic liquid mixtures consisting of 1-butyl-3-methyl-imidazolium acetic ([BMIm]Ac) and 1-butyl-3-methyl-imidazolium tetraflouroborate ([BMIm][BF(4)]). The effect of reaction parameters such as the amount of enzyme used, the reaction temperature, the mas... | 10.1021/jf303096c | 22,920,292 | D002175:Candida; D002384:Catalysis; D005656:Fungal Proteins; D052578:Ionic Liquids; D008049:Lipase; D010168:Palmitates; D013213:Starch | Journal of agricultural and food chemistry | 2,012 | D005656:Fungal Proteins; D052578:Ionic Liquids; D010168:Palmitates; D013213:Starch; D008049:Lipase |
Asymmetric bi-layer PFSA membranes as model systems for the study of water management in the PEMFC. | New bi-layer PFSA membranes made of Nafion® NRE212 and Aquivion™ E79-05s with different equivalent weights are prepared with the aim of managing water repartition in the PEMFC. The membrane water transport properties, i.e. back-diffusion and electroosmosis, as well as the electrochemical performances, are compared to t... | 10.1039/c4cp02777a | 25,171,457 | Physical chemistry chemical physics : PCCP | 2,014 | ||
Modeling of Tool-Tissue Interactions for Computer-Based Surgical Simulation: A Literature Review. | Surgical simulators present a safe and potentially effective method for surgical training, and can also be used in robot-assisted surgery for pre- and intra-operative planning. Accurate modeling of the interaction between surgical instruments and organs has been recognized as a key requirement in the development of hig... | 10.1162/pres.17.5.463 | 20,119,508 | Presence (Cambridge, Mass.) | 2,008 | ||
Pial Arteriovenous Fistula: A Brief Review and Report of 14 Surgically Treated Cases. | OBJECTIVE
The authors report their successful experience of treating 14 cases of pial arteriovenous fistula (PAVF) by direct surgery.
METHODS
During the period January 2010 to April 2017, 14 patients with PAVF were treated by surgery. Only those patients were selected who had a single arterial feeding channel. There ... | 10.1016/j.wneu.2017.11.121 | 29,191,547 | D000293:Adolescent; D000328:Adult; D001164:Arteriovenous Fistula; D002533:Cerebral Angiography; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D002538:Intracranial Arteriovenous Malformations; D008279:Magnetic Resonance Imaging; D0... | World neurosurgery | 2,018 | |
Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea. | BACKGROUND
Indirect evidence implicates endothelial dysfunction in the pathogenesis of vascular diseases associated with obstructive sleep apnea (OSA). We investigated directly whether dysfunction and inflammation occur in vivo in the vascular endothelium of patients with OSA. The effects of continuous positive airway ... | 10.1161/CIRCULATIONAHA.107.741512 | 18,413,499 | D000328:Adult; D015415:Biomarkers; D045422:Continuous Positive Airway Pressure; D051546:Cyclooxygenase 2; D004730:Endothelium, Vascular; D005260:Female; D006801:Humans; D000860:Hypoxia; D008297:Male; D008875:Middle Aged; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III; D018384:Oxidative St... | Circulation | 2,008 | D015415:Biomarkers; C002744:3-nitrotyrosine; D014443:Tyrosine; C496319:NOS2 protein, human; C496314:NOS3 protein, human; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III; D051546:Cyclooxygenase 2 |
Similarities and differences in gut microbiome composition correlate with dietary patterns of Indian and Chinese adults. | The interaction between diet and gut microbiota, and ultimately their link to health, has turned into the concentration of huge research. However, this relationship still needs to be fully characterized, particularly in case of the Asian population. We compared the fecal bacterial diversity and composition of healthy I... | 10.1186/s13568-018-0632-1 | 29,936,607 | AMB Express | 2,018 | ||
Lack of X-linked inhibitor of apoptosis protein leads to increased apoptosis and tissue loss following neonatal brain injury. | Neurological deficits caused by H-I (hypoxia-ischaemia) to the perinatal brain are often severely debilitating and lead to motor impairment, intellectual disability and seizures. Perinatal brain injury is distinct from adult brain injury in that the developing brain is undergoing the normal process of neuronal eliminat... | 19,570,023 | D000818:Animals; D000831:Animals, Newborn; D017209:Apoptosis; D001284:Atrophy; D001921:Brain; D001930:Brain Injuries; D005260:Female; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D051636:X-Linked Inhibitor of Apoptosis Protein | ASN neuro | 2,009 | D051636:X-Linked Inhibitor of Apoptosis Protein | |
Impact of a one-year lifestyle modification program on cholesterol efflux capacities in men with abdominal obesity and dyslipidemia. | Cholesterol efflux capacities (CECs) are negatively associated with cardiovascular disease risk, irrespective of plasma high-density lipoprotein (HDL) cholesterol levels. Whether interventions targeting lifestyle improve HDL-CECs is unknown. Our objective was to determine whether improving dietary quality and increasin... | 10.1152/ajpendo.00127.2018 | 29,870,675 | D052242:Adiponectin; D000328:Adult; D016632:Apolipoprotein A-I; D001055:Apolipoproteins B; D031204:Caloric Restriction; D000072599:Cardiorespiratory Fitness; D002784:Cholesterol; D008076:Cholesterol, HDL; D000072001:Diet, Healthy; D050171:Dyslipidemias; D015444:Exercise; D056945:Hep G2 Cells; D006801:Humans; D008019:Li... | American journal of physiology. Endocrinology and metabolism | 2,018 | D052242:Adiponectin; D016632:Apolipoprotein A-I; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D014280:Triglycerides; D014316:Tritium; D002784:Cholesterol; C472125:PCSK9 protein, human; D000071449:Proprotein Convertase 9 |
Effectiveness of tuberculosis prophylaxis in patients with HIV/AIDS - retrospective analysis of data from Almaty, Kazakhstan, 2010-2015. | INTRODUCTION
According to data from the National Centre for Prevention and Control of AIDS, in the Republic of Kazakhstan, 45.8% of patients in the symptomatic stages of HIV infection are diagnosed with tuberculosis (TB) which is the cause of death in 36% of patients infected with HIV.
OBJECTIVE
The aim of the study ... | 10.26444/aaem/118611 | 33,356,080 | D000163:Acquired Immunodeficiency Syndrome; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000995:Antitubercular Agents; D018890:Chemoprevention; D060085:Coinfection; D005260:Female; D015658:HIV Infections; D006801:Humans; D015994:Incidence; D007623:Kazakhstan; D008297:Male; D008875:Middle Aged; D012189:Retro... | Annals of agricultural and environmental medicine : AAEM | 2,020 | D000995:Antitubercular Agents |
Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses. | The bat coronaviruses (CoV) BANAL-20-52 and BANAL-20-236 are two newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) closely related coronaviruses (SC2r-CoV) and the genome of BANAL-20-52 shares the highest homology with SARS-CoV-2. However, the risk of their potential zoonotic transmission ha... | 10.1038/s41421-023-00581-9 | 37,507,385 | Cell discovery | 2,023 | ||
Noise analysis in direct detection and coherent detection phase-sensitive optical time-domain reflectometry systems. | This study compares noise and signal-to-noise ratio (SNR) in direct detection and coherent detection fiber-based distributed acoustic sensing (DAS) systems. Both detection schemes employ the dynamic analysis of Rayleigh-backscattered light in phase-sensitive optical time-domain reflectometry (ΦOTDR) systems. Through th... | 10.1364/OE.487978 | 37,710,820 | Optics express | 2,023 | ||
Effect of rice protein on the gelatinization and retrogradation properties of rice starch. | In this study, rice starch (RS) was mixed with varying amounts of rice protein (RP; 0 % to 16 %) to explore the effects of protein on the gelatinization and retrogradation of starch during storage. The increased RP addition decreased the viscosity and gelatinization enthalpy of the mixtures but caused an upward trend i... | 10.1016/j.ijbiomac.2023.125061 | 37,247,715 | D012275:Oryza; D013213:Starch; D013696:Temperature; D013816:Thermodynamics; D005782:Gels; D014867:Water | International journal of biological macromolecules | 2,023 | D013213:Starch; D005782:Gels; D014867:Water |
Serological Evidence for Influenza A Virus Exposure in Wild Birds in Trinidad & Tobago. | Migratory waterfowl and shorebirds are known to be important reservoirs for influenza A viruses (IAV) and they have been repeatedly implicated as causing avian influenza virus (AIV) outbreaks in domestic poultry flocks worldwide. In recent years, wild birds have been implicated in spreading zoonotic H5 influenza viruse... | 10.3390/vetsci5020050 | 29,747,454 | Veterinary sciences | 2,018 | ||
Nutrition practices and outcomes in patients with pediatric acute respiratory distress syndrome. | BACKGROUND
Pediatric acute respiratory distress syndrome (PARDS) remains a significant cause of morbidity and mortality. Evidence suggests enteral nutrition (EN) may be protective in critically ill children.
METHODS
This is a retrospective cohort study comparing intubated patients with PARDS who received EEN and thos... | 10.1002/jpen.2320 | 34,961,948 | D002648:Child; D004750:Enteral Nutrition; D006801:Humans; D015278:Intensive Care Units, Pediatric; D009752:Nutritional Status; D012128:Respiratory Distress Syndrome; D012189:Retrospective Studies | JPEN. Journal of parenteral and enteral nutrition | 2,022 | |
Use of moclobemide in children with attention deficit hyperactivity disorder. | A monoamine oxidase hypothesis for the cause of attention deficit hyperactivity disorder has recently been established (Shekim et al. 1986). To test this, moclobemide, a new and reversible inhibitor of monoamine oxidase-A, was administered to 12 children between the ages of 6 and 13 years, diagnosed as attention defici... | 10.1007/BF02246258 | 1,546,129 | D000293:Adolescent; D000328:Adult; D001288:Attention; D001289:Attention Deficit Disorder with Hyperactivity; D001519:Behavior; D001549:Benzamides; D001931:Brain Mapping; D003700:Delta Rhythm; D004562:Electrocardiography; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D0209... | Psychopharmacology | 1,992 | D001549:Benzamides; D008996:Monoamine Oxidase Inhibitors; D020912:Moclobemide |
Gene expression profiling of epithelial ovarian tumours correlated with malignant potential. | BACKGROUND
Epithelial ovarian tumours exhibit a range of malignant potential, presenting distinct clinical phenotypes. Improved knowledge of gene expression changes and functional pathways associated with these clinical phenotypes may lead to new treatment targets, markers for early detection and a better understanding... | 10.1186/1476-4598-3-27 | 15,471,544 | D016000:Cluster Analysis; D004847:Epithelial Cells; D005260:Female; D020869:Gene Expression Profiling; D006801:Humans; D005810:Multigene Family; D009364:Neoplasm Recurrence, Local; D020411:Oligonucleotide Array Sequence Analysis; D010051:Ovarian Neoplasms; D020133:Reverse Transcriptase Polymerase Chain Reaction | Molecular cancer | 2,004 | |
Lactoferrin is an estrogen responsive protein in the uterus of mice and rats. | To identify lactoferrin (LF) and determine its estrogen-responsiveness in the rat uterus, immature Sprague-Dawley rats were untreated or subcutaneously injected with 17beta-estradiol (500 microg/kg) for 3 days and uterine tissues collected. Outbred immature CD-1 mice, treated with 17beta-estradiol, provided the positiv... | 10.1016/s0890-6238(00)00061-7 | 10,825,673 | D000818:Animals; D015415:Biomarkers; D015153:Blotting, Western; D003176:Complement C3; D004591:Electrophoresis, Polyacrylamide Gel; D004847:Epithelial Cells; D004958:Estradiol; D004968:Estrogens, Non-Steroidal; D005260:Female; D007124:Immunoenzyme Techniques; D007279:Injections, Subcutaneous; D007781:Lactoferrin; D0513... | Reproductive toxicology (Elmsford, N.Y.) | 2,000 | D015415:Biomarkers; D003176:Complement C3; D004968:Estrogens, Non-Steroidal; D004958:Estradiol; D007781:Lactoferrin |
Predictive ability of the SCORE Belgium risk chart for cardiovascular mortality. | BACKGROUND
The identification of persons at high cardiovascular risk is of primary importance in the context of cardiovascular prevention. Accuracy and precision of risk assessment are essential properties. We developed a calibrated SCORE risk chart (Systematic COronary Risk Evaluation) for calculating the absolute 10-... | 10.1016/j.ijcard.2009.03.101 | 19,386,372 | D000328:Adult; D000368:Aged; D001530:Belgium; D002318:Cardiovascular Diseases; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012372:ROC Curve; D015203:Reproducibility of Results; D018570:Risk Assessment; D012307:Risk Factors; D012680:S... | International journal of cardiology | 2,010 | |
Depletion of the cullin Cdc53p induces morphogenetic changes in Candida albicans. | Candida albicans is an important opportunistic human fungal pathogen that can cause both mucosal and systemic infections in immunocompromised patients. Critical for the virulence of C. albicans is its ability to undergo a morphological transition from yeast to hyphal growth mode. Proper induction of filamentation is de... | 10.1128/EC.00332-08 | 19,270,112 | D002176:Candida albicans; D044842:Cullin Proteins; D005656:Fungal Proteins; D018507:Gene Expression Regulation, Developmental; D015966:Gene Expression Regulation, Fungal; D009024:Morphogenesis | Eukaryotic cell | 2,009 | D044842:Cullin Proteins; D005656:Fungal Proteins |
A 50-kDa isoform of mouse brain acyl-CoA hydrolase: expression and molecular properties. | Brain acyl-CoA hydrolase (BACH) is responsible for most of the long-chain acyl-CoA hydrolyzing activity in the brain and is localized exclusively in neurons. There are two BACH isoforms: the major isoform, a 43-kDa BACH, and a lesser isoform, a 50-kDa BACH. In our previous work [Brain Res. Mol. Brain Res. 98 (2002) 81]... | 10.1016/j.abb.2004.06.005 | 15,288,813 | D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain; D001923:Brain Chemistry; D045744:Cell Line, Tumor; D004789:Enzyme Activation; D015972:Gene Expression Regulation, Neoplastic; D007527:Isoenzymes; D051379:Mice; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009447:Neuroblastoma; D010170:Palmitoyl... | Archives of biochemistry and biophysics | 2,004 | D007527:Isoenzymes; D012333:RNA, Messenger; D011994:Recombinant Proteins; D010170:Palmitoyl-CoA Hydrolase |
The colorado plateaus: cultural dynamics and paleoenvironment. | Convergent archeological, geological, palynological, dendrochronological, and radiometric data provide a paleoenvironmental record for the American Southwest at a level of detail and time resolution not previously achieved. Many prehistoric cultural and demographic changes on the Colorado Plateaus coincided with enviro... | 10.1126/science.205.4411.1089 | 17,735,032 | Science (New York, N.Y.) | 1,979 | ||
[Characteristics and selectivity of photocatalytic-degradation of tetracycline hydrochloride]. | The photocatalytic-degradation behavior of tetracycline hydrochloride (TTC) was studied. The catalyst used was photosensitive semiconductor titanium dioxide (TiO2). The results showed that the photocatalytic degradation of TTC was well fitted to first order reaction kinetics model, and the adsorption was the control st... | 24,812,956 | D000327:Adsorption; D000900:Anti-Bacterial Agents; D002384:Catalysis; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D055668:Photochemical Processes; D013752:Tetracycline; D014025:Titanium | Huan jing ke xue= Huanjing kexue | 2,014 | D000900:Anti-Bacterial Agents; C009495:titanium dioxide; D014025:Titanium; D013752:Tetracycline | |
Pyrene-biimidazole based Ru(II) and Os(II) complexes as highly efficient probes for the visible and near-infrared detection of cyanide in aqueous media. | Two pyrenyl-biimidazole based mononuclear Ru(II) and Os(II) complexes of the type [(bpy)2M(Py-BiimzH2)](2+) (M = Ru(II) and Os(II)), where Py-BiimzH2 = 10-(1-H-imidazole-2-yl)-9H-pyreno[4,5-d]imidazole and bpy = 2,2'-bipyridine, have been synthesized and thoroughly characterized in this work using various analytical to... | 10.1039/c5dt03766b | 26,592,760 | Dalton transactions (Cambridge, England : 2003) | 2,015 | ||
Modelling the vicious circle between obesity and physical activity in children and adolescents using a bivariate probit model with endogenous regressors. | The increasing prevalence of obesity in children and adolescents has become one of the most important public health issues around the world. Lack of physical activity is a risk factor for obesity, while being obese could reduce the likelihood of participating in physical activity. Failing to account for the endogeneity... | 10.1017/S0021932013000722 | 24,423,649 | D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D015233:Models, Statistical; D009043:Motor Activity; D009765:Obesity; D050177:Overweight; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D013624:Taiwan | Journal of biosocial science | 2,015 | |
Increase in fluidity of human placental syncytiotrophoblastic brush-border membrane with advancement of gestational age: a fluorescence polarization study. | The syncytiotrophoblastic brush-border membrane (BBM) of human placenta plays a vital role in the exchange of metabolites between mother and developing fetus. The fluidity of this membrane renders its selective permeable character. To meet the changing needs of the growing fetus with the progress of gestational age cha... | 10.1016/0005-2736(95)00066-c | 7,794,971 | D001692:Biological Transport; D005454:Fluorescence Polarization; D005865:Gestational Age; D005947:Glucose; D006801:Humans; D008081:Liposomes; D008560:Membrane Fluidity; D008563:Membrane Lipids; D008565:Membrane Proteins; D008871:Microvilli; D010920:Placenta; D013696:Temperature | Biochimica et biophysica acta | 1,995 | D008081:Liposomes; D008563:Membrane Lipids; D008565:Membrane Proteins; D005947:Glucose |
Acute effects of transjugular intrahepatic portosystemic stent-shunt (TIPSS) procedure on renal blood flow and cardiopulmonary hemodynamics in cirrhosis. | OBJECTIVE
An acute increase in portal pressure is associated with an immediate reduction in renal blood flow. It has been suggested that this supports the presence of an hepatorenal reflex. In this study, we used TIPSS placement as a model to investigate the effect of an acute reduction in portal pressure on renal bloo... | 10.1111/j.1572-0241.1998.00705.x | 9,860,410 | D001794:Blood Pressure; D003326:Coronary Circulation; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008103:Liver Cirrhosis; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D011652:Pulmonary Circulation; D012079:Renal Circulation | The American journal of gastroenterology | 1,998 | |
A Brief Description of How Teachers Experience An Infographic Loneliness Toolkit About Supporting Adolescents to Overcome Loneliness. | Loneliness is a common experience amongst adolescents. As adolescents spend much of their time in school, it is important that school staff can support adolescent students experiencing loneliness. The current study aimed to explore teachers' experiences of a 1-page loneliness toolkit regarding adolescent loneliness. An... | 10.1177/13591045231209353 | 37,933,664 | Clinical child psychology and psychiatry | 2,023 | ||
Contrast-enhanced MRI lesions during treatment with interferonbeta-1b predict increase in T1 black hole volume in patients with relapsing-remitting multiple sclerosis. | T1 black holes (BH) have been found to represent focal areas of substantial central nervous system tissue damage in multiple sclerosis (MS) patients. We examined the development of T1 BH over a three-year period of treatment with interferon (IFN)beta-1b in a group of 20 patients with relapsing-remitting MS. The number ... | 10.1191/1352458505ms1147oa | 15,794,386 | D000276:Adjuvants, Immunologic; D000328:Adult; D001921:Brain; D005260:Female; D006801:Humans; D000068576:Interferon beta-1b; D016899:Interferon-beta; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting; D011237:Predictive V... | Multiple sclerosis (Houndmills, Basingstoke, England) | 2,005 | D000276:Adjuvants, Immunologic; D000068576:Interferon beta-1b; D016899:Interferon-beta |
[Psychological functions in children treated for acute lymphatic leukemia. A 5-year follow-up of three different age groups of children]. | All the children, five girls and ten boys aged 8-16 years, mean 11 years, with acute lymphoblastic leukemia which had been diagnosed in 1980, 1981 or 1983 and was still in remission in 1990, were examined. The treatment included intratecal methotrexate, but no irradiation. Mean age at the time of diagnosis was 4.5 year... | 9,235,680 | D000293:Adolescent; D000964:Antimetabolites, Antineoplastic; D002648:Child; D002652:Child Behavior; D003071:Cognition; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007361:Intelligence Tests; D008297:Male; D008727:Methotrexate; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma; D011581:Psychological ... | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke | 1,997 | D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate | |
Oxidative P-P Bond Addition to Cobalt(-I): Formation of a Low-Spin Cobalt(III) Phosphanido Complex. | The first homoleptic cobalt phosphanido complex [K(thf)4 ][Co{1,2-(PtBu2 )2 C2 B10 H12 }2 ] (1) was prepared by an unprecedented oxidative P-P bond addition of an ortho-carborane-substituted 1,2-diphosphetane to cobalt(-I) in [K(thf)0.2 ][Co(η4 -cod)2 )] (cod=1,5-cycloctadiene). Compound 1 is a rare distorted tetrahedr... | 10.1002/anie.201709140 | 28,980,374 | Angewandte Chemie (International ed. in English) | 2,017 | ||
Structure of the Mucosal and Stool Microbiome in Lynch Syndrome. | The gut microbiota has been associated with colorectal cancer (CRC), but causal alterations preceding CRC have not been elucidated. To prospectively assess microbiome changes prior to colorectal neoplasia, we investigated samples from 100 Lynch syndrome patients using 16S rRNA gene sequencing of colon biopsies, coupled... | 10.1016/j.chom.2020.03.005 | 32,240,601 | D000236:Adenoma; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003082:Colectomy; D003110:Colonic Neoplasms; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis; D005243:Feces; D005260:Female; D000069196:Gastrointestinal Microbiome; D006801:Humans; D008297:Male; D056186:Metagenomics; D008875:Middle Aged; D0... | Cell host & microbe | 2,020 | D012336:RNA, Ribosomal, 16S |
Expression of KIR and C-type lectin receptors in Behcet's disease. | OBJECTIVE
Behçet's disease (BD) is a multisystemic disorder with a possible underlying pathology of immune-mediated vasculitis. Genetic susceptibility associated with HLA-B*51 and B*2702 has been implicated in its pathogenesis. Considering the recently defined regulatory mechanisms of NK cells through HLA class I bindi... | 10.1093/rheumatology/keh063 | 14,679,294 | D000328:Adult; D000368:Aged; D015703:Antigens, CD; D001528:Behcet Syndrome; D005260:Female; D015235:HLA-B Antigens; D059949:HLA-B51 Antigen; D006801:Humans; D007694:Killer Cells, Natural; D037181:Lectins, C-Type; D008297:Male; D008875:Middle Aged; D051920:NK Cell Lectin-Like Receptor Subfamily D; D011971:Receptors, Imm... | Rheumatology (Oxford, England) | 2,004 | D015703:Antigens, CD; D015235:HLA-B Antigens; D059949:HLA-B51 Antigen; C042388:HLA-Bw4 antigen; C515083:KIR3DL1 protein, human; C497869:KLRD1 protein, human; D037181:Lectins, C-Type; D051920:NK Cell Lectin-Like Receptor Subfamily D; D011971:Receptors, Immunologic; D054340:Receptors, KIR; D054341:Receptors, KIR3DL1 |
Right ventricular myocardial infarction: when the power fails. | Learn how to recognize this common complication of an acute inferior or posterior wall myocardial infarction and to give patients the correct treatment. | 10.1097/00003465-200207000-00001 | 12,134,116 | D004108:Dilatation, Pathologic; D004562:Electrocardiography; D006801:Humans; D007022:Hypotension; D007601:Jugular Veins; D009203:Myocardial Infarction; D009730:Nursing Assessment; D018497:Ventricular Dysfunction, Right | Dimensions of critical care nursing : DCCN | 2,002 | |
[Place and cause of death in community-dwelling disabled elderly people]. | AIM
To examine the place and cause of death in community-dwelling disabled elderly people.
METHODS
The baseline data of 1,875 participants and their caregivers in the Nagoya Longitudinal Study for Frail Elderly were used for the analysis. Cox proportional hazard models were used to assess the associations between the... | 10.3143/geriatrics.50.797 | 24,622,228 | D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D015331:Cohort Studies; D006233:Disabled Persons; D005260:Female; D006760:Hospitalization; D006801:Humans; D057187:Independent Living; D008297:Male; D011446:Prospective Studies; D012737:Sex Factors | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics | 2,013 | |
[EGFR and HER2 gene expression status and their correlation in non-small cell lung cancer]. | OBJECTIVE
To explore epidermal growth factor receptor (EGFR) and HER2 gene status, to assess the correlation between EGFR and HER2 gene status, and to investigate the role of copy number increase and amplification of EGFR gene and HER2 gene in the tumorigenesis and disease progression of non-small-cell lung cancer.
M... | 17,069,674 | D002289:Carcinoma, Non-Small-Cell Lung; D002886:Chromosomes, Human, Pair 17; D002897:Chromosomes, Human, Pair 7; D005784:Gene Amplification; D018628:Gene Dosage; D015972:Gene Expression Regulation, Neoplastic; D018773:Genes, erbB-1; D018734:Genes, erbB-2; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D00... | Zhonghua bing li xue za zhi = Chinese journal of pathology | 2,006 | ||
Stochastic kinetic analysis of the Escherichia coli stress circuit using sigma(32)-targeted antisense. | A stochastic Petri net model was developed for simulating the sigma(32) stress circuit in E. coli. Transcription factor sigma(32) is the principal regulator of the response of E. coli to heat shock. Stochastic Petri net (SPN) models are well suited for kinetics characterization of fluxes in biochemical pathways. Notabl... | 10.1002/bit.1171 | 11,536,134 | D016375:Antisense Elements (Genetics); D003198:Computer Simulation; D004926:Escherichia coli; D000431:Ethanol; D015964:Gene Expression Regulation, Bacterial; D006360:Heat-Shock Proteins; D008954:Models, Biological; D011994:Recombinant Proteins; D012808:Sigma Factor; D012997:Solvents; D013269:Stochastic Processes | Biotechnology and bioengineering | 2,001 | D016375:Antisense Elements (Genetics); D006360:Heat-Shock Proteins; D011994:Recombinant Proteins; D012808:Sigma Factor; D012997:Solvents; D000431:Ethanol |
Removal of textile dyes by benefited marine shells wastes: From circular economy to multi-phenomenological modeling. | Marine shell wastes were thermally activated and characterized as aragonite and calcite phases and were used in the removal of synthetic anionic dyes, Bright Blue Acid (NB180) and Reactive Red 133 (RR133). Benefited marine shells were classified as low-cost (USD 0.33/g of adsorbent) in comparison with other reported ma... | 10.1016/j.jenvman.2021.113222 | 34,246,908 | D000327:Adsorption; D004396:Coloring Agents; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D013784:Textiles; D014874:Water Pollutants, Chemical | Journal of environmental management | 2,021 | D004396:Coloring Agents; D014874:Water Pollutants, Chemical |
Public health nutrition workforce composition, core functions, competencies and capacity: perspectives of advanced-level practitioners in Australia. | OBJECTIVES
To investigate the attitudes, experiences and beliefs of advanced-level public health nutritionists with respect to public health nutrition workforce composition, core functions, competency requirements and existing workforce capacity.
DESIGN
Qualitative study using structured interviews.
SETTING
Austral... | 10.1079/phn2003465 | 14,690,042 | D001315:Australia; D004046:Dietetics; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007407:Interviews as Topic; D009747:Nutritional Physiological Phenomena; D011361:Professional Competence; D011634:Public Health; D011635:Public Health Administration; D013192:Staff Development; D000078329:Workforce | Public health nutrition | 2,003 | |
Random dominance and childhood migraine: a new marker? A controlled study of laterality in children with migraine. | We assessed various aspects of laterality by direct observation in children with migraine and peer controls, with special reference to the frequency of random dominance. This frequency varied with the test battery used, being lower on the Edinburgh and Oldfield inventories which measure hand-use preference, and higher ... | 3,678,941 | D000293:Adolescent; D002648:Child; D005260:Female; D007839:Functional Laterality; D006801:Humans; D006948:Hyperkinesis; D008297:Male; D008881:Migraine Disorders; D009460:Neurologic Examination | Functional neurology | 1,987 | ||
Tests of association of lymphocyte alloantigen genotypes with resistance to viral oncogenesis in chickens. 2. Rous sarcoma and lymphoid leukosis in progeny derived from 6(3) X 15(1) and 100 X 6(3) crosses. | Chickens from inbred line RPRL 6(3) are resistant to virally-induced Marek's disease (MD) and lymphoid leukosis (LL) and are relatively strong regressors of virally induced Rous sarcomas. Line 6(3) chickens are homozygous for three independent loci determining surface alloantigens of lymphocytes, Th-1 and Ly-4 on thymu... | 10.3382/ps.0640039 | 2,983,298 | D000818:Animals; D000914:Antibodies, Viral; D001353:Avian Leukosis; D001354:Avian Leukosis Virus; D001358:Avian Sarcoma Viruses; D002645:Chickens; D003433:Crosses, Genetic; D005260:Female; D005838:Genotype; D007519:Isoantigens; D008214:Lymphocytes; D008297:Male; D009500:Neutralization Tests; D001357:Sarcoma, Avian | Poultry science | 1,985 | D000914:Antibodies, Viral; D007519:Isoantigens |
[Automated external defibrillation: new French guidelines and their application]. | Unexpected cardiac arrest, that is, sudden death in adults, accounts for nearly 50 000 deaths each year in France. Automated external defibrillation performed in public places improves victims' survival. Automated external defibrillators can be made available in 2 different ways: for "self-service" by members of the pu... | 10.1016/j.lpm.2008.02.008 | 18,440,762 | D047548:Defibrillators; D005392:First Aid; D005602:France; D006266:Health Education; D006801:Humans; D017410:Practice Guidelines as Topic | Presse medicale (Paris, France : 1983) | 2,008 | |
Adipose-Derived Stem Cell Coculturing Stimulates Integrin-Mediated Extracellular Matrix Adhesion of Melanocytes by Upregulating Growth Factors. | Coculture with adipose-derived stem cells (ADSCs) can stimulate proliferation and migration of melanocytes. To enhance outcomes of skin disorders caused by melanocyte loss or death, mixed transplantation with ADSCs has been suggested. However, role of cocultured ADSCs in proliferation and migration of melanocytes remai... | 10.4062/biomolther.2018.203 | 30,530,924 | Biomolecules & therapeutics | 2,019 | ||
Microsurgical transfer of the second toe for congenital deficiency of the thumb. | Twelve second-toe transfers have been performed to substitute for thumbs congenitally deficient through constriction ring syndrome, symbrachydactyly, and true transverse arrest. The children were on average 3 years of age, and the youngest was undertaken at 10 months. Anatomic variations were the rule in the six cases ... | 10.1097/00006534-198810000-00017 | 3,420,188 | D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D008866:Microsurgery; D013933:Thumb; D014034:Toes | Plastic and reconstructive surgery | 1,988 | |
Temporal changes in vascular reactivity in early diabetes mellitus in rats: role of changes in endothelial factors and in phosphodiesterase activity. | The aims of this study were to study the influence of the duration of diabetes, the role of endothelial-derived vasodilators, and the role of phosphodiesterase (PDE) isoform activity in the early changes in vascular reactivity of aortic rings from diabetic rats. Diabetes mellitus was induced in female rats by intraveno... | 10.1152/ajpheart.00102.2009 | 19,542,492 | D000109:Acetylcholine; D000493:Allopurinol; D000818:Animals; D001013:Aorta, Thoracic; D001786:Blood Glucose; D054677:Cyclic Nucleotide Phosphodiesterases, Type 1; D054678:Cyclic Nucleotide Phosphodiesterases, Type 2; D054684:Cyclic Nucleotide Phosphodiesterases, Type 3; D054703:Cyclic Nucleotide Phosphodiesterases, Typ... | American journal of physiology. Heart and circulatory physiology | 2,009 | C097114:1,3-dimethyl-6-(2-propoxy-5-methanesulfonylamidophenyl)pyrazolo(3,4-d)pyrimidin-4(5H)-one; D001786:Blood Glucose; D020030:Nitric Oxide Donors; D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D010656:Phenylephrine; D000493:Allopurinol; D026423:S-Nitroso-N-Acetylpenicillamine; D010727:Phosphoric Diest... |
The Cuban National Cancer Registry: 1986-1990. | In Cuba, the illness that produces most deaths among 1-64-year-olds is cancer. Over 65, it is the second cause of death after heart diseases. A National Cancer Registry was created 1964. Its main goals are to register all malignant neoplasms diagnosed in the country, to study this disease from the statistical and epide... | 10.1023/a:1007463826932 | 9,663,522 | D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D003462:Cuba; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D009369:Neoplasms; D016017:Odds Ratio; D012042:Registries; D0176... | European journal of epidemiology | 1,998 | |
Quality evaluation and in vitro interaction studies between levofloxacin 250mg and diclofenac sodium 50mg tablets. | Fluoroquinolones are broad-spectrum antibiotics, work against Gram-positive and Gram-negative bacteria and are a clinically proven option for many resistant infections. Among fluoroquinolones Levofloxacin works best against acute sinusitis, inflammation of the lower airways, acute exacerbation of chronic bronchitis, co... | 25,553,690 | D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002626:Chemistry, Pharmaceutical; D004008:Diclofenac; D004347:Drug Interactions; D005750:Gastric Juice; D006244:Hardness; D006863:Hydrogen-Ion Concentration; D007419:Intestinal Secretions; D007700:Kinetics; D064704:Levofloxacin; D008956:Mo... | Pakistan journal of pharmaceutical sciences | 2,015 | D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac; D064704:Levofloxacin | |
Developmental assessment of the technology-dependent infant and young child. | Appropriate developmental intervention for the technology-dependent infant or young child has its basis in a carefully designed and thorough assessment. The role of the nurse is central in this process. This article guides the nurse through an analysis of developmentally relevant medical considerations, an examination ... | 1,625,962 | D002657:Child Development; D002675:Child, Preschool; D005190:Family; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009730:Nursing Assessment; D010371:Pediatric Nursing; D013673:Technology Assessment, Biomedical | Pediatric nursing | 1,992 | ||
Interaction Between Ambient Temperature, Hypoxia, and Load Carriage on Respiratory Muscle Fatigue. | BACKGROUND: While respiratory muscle fatigue is present following load carriage activity at sea level, the effect of environmental conditions on respiratory strength while undertaking load carriage is unknown.METHODS: The effect of thoracic load carriage during walks (5.5 km) in four environments [(thermo-neutral sea l... | 10.3357/AMHP.5108.2018 | 30,352,647 | D000328:Adult; D000531:Altitude; D003080:Cold Temperature; D005260:Female; D006801:Humans; D000860:Hypoxia; D008297:Male; D018763:Muscle Fatigue; D012132:Respiratory Muscles; D013696:Temperature; D016474:Weight-Bearing; D055815:Young Adult | Aerospace medicine and human performance | 2,018 | |
Successful Perioperative Combination of High-Dose FVIII Therapy Followed by Emicizumab in a Patient with Hemophilia A with Inhibitors. | We managed perioperative hemostasis for a 72-year-old man with hemophilia A and low inhibitor titers (3 BU/mL), who underwent osteosynthesis for supracondylar fracture of the left humerus. He was treated perioperatively using the combination of high doses of factor VIII (FVIII) with recombinant human Factor VIII Fc fus... | 10.1055/s-0039-3401001 | 31,815,248 | TH open : companion journal to thrombosis and haemostasis | 2,019 | ||
Hyperostosis in siblings. | Infantile cortical hyperostosis - Caffey-Silverman disease - is a familial disorder manifesting in the late fetal period or infancy with excessive periosteal bone formation. Signs and symptoms regress spontaneously within months and result in expanded, deformed bones. The paucity of clinical symptoms may lead to delaye... | 10.7196/SAMJ.2016.v106i6.11007 | 27,245,539 | D002675:Child, Preschool; D024042:Collagen Type I; D000090602:Collagen Type I, alpha 1 Chain; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D006958:Hyperostosis, Cortical, Congenital; D007223:Infant; D009154:Mutation; D010013:Osteogenesis Imperfecta; D035781:Siblings | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde | 2,016 | D024042:Collagen Type I; D000090602:Collagen Type I, alpha 1 Chain |
Secretory function of vascular endothelium and its implication in the action of vasoactive drugs. | Monolayer of endothelial cells is no longer considered as a plain mechanical barrier which separates blood from the rest of our body. Endothelium became recognised as a powerful generator of substances which, by interaction with blood cells or blood plasma maintain homeostasis in the circulation [2, 4, 5, 10, 26, 38, 4... | 2,263,533 | D000818:Animals; D004730:Endothelium, Vascular; D011464:Epoprostenol; D006801:Humans; D009569:Nitric Oxide; D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents | Polish journal of pharmacology and pharmacy | 1,990 | D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D009569:Nitric Oxide; D011464:Epoprostenol | |
Rats' choices with token stimuli in concurrent variable-interval schedules. | Four rats responded on concurrent variable-interval schedules that delivered token stimuli (stimulus lights arranged vertically above each of two side levers). During exchange periods, each token could be exchanged for one food pellet by responding on a center lever, with one response required for each pellet delivery.... | 10.1002/jeab.101 | 25,130,299 | D000818:Animals; D002755:Choice Behavior; D003216:Conditioning, Operant; D003463:Cues; D008297:Male; D051381:Rats; D020318:Rats, Long-Evans; D012055:Reinforcement Schedule; D014040:Token Economy | Journal of the experimental analysis of behavior | 2,014 |
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