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Detection of the tetM resistance determinant among phenotypically sensitive Ureaplasma species by a novel real-time PCR method.
The study aimed to identify the proportion of tetM-positive Ureaplasma spp. isolates phenotypically susceptible to tetracycline by real-time PCR. Ureaplasma spp. strains of urogenital origin were isolated from 100 female or male adults on A7 agar plates. The presence of Ureaplasma was confirmed by the presence of ureas...
25,467,173
D000328:Adult; D000900:Anti-Bacterial Agents; D005260:Female; D005798:Genes, Bacterial; D005838:Genotype; D006115:Greece; D006801:Humans; D008297:Male; D010641:Phenotype; D060888:Real-Time Polymerase Chain Reaction; D013752:Tetracycline; D014509:Ureaplasma; D016990:Ureaplasma urealyticum; D014552:Urinary Tract Infectio...
Diagnostic microbiology and infectious disease
2,015
D000900:Anti-Bacterial Agents; D013752:Tetracycline
An Enhanced Approach for Economic Evaluation of Long-Term Benefits of School-Based Health Promotion Programs.
Chronic diseases constitute a tremendous public health burden globally. Poor nutrition, inactive lifestyles, and obesity are established independent risk factors for chronic diseases. Public health decision-makers are in desperate need of effective and cost-effective programs that prevent chronic diseases. To date, mos...
10.3390/nu12041101
32,316,099
D000293:Adolescent; D001835:Body Weight; D002648:Child; D002908:Chronic Disease; D003362:Cost-Benefit Analysis; D015444:Exercise; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D009752:Nutritional Status; D009765:Obesity; D015397:Program Evaluation; D011634:Public Health; D019057:Quality-Adjusted Lif...
Nutrients
2,020
The Streptomyces filipinensis Gamma-Butyrolactone System Reveals Novel Clues for Understanding the Control of Secondary Metabolism.
Streptomyces γ-butyrolactones (GBLs) are quorum sensing communication signals triggering antibiotic production. The GBL system of Streptomyces filipinensis, the producer of the antifungal agent filipin, has been investigated. Inactivation of sfbR (for γ-butyrolactone receptor), a GBL receptor, resulted in a strong dec...
10.1128/AEM.00443-20
32,631,864
D015107:4-Butyrolactone; D000935:Antifungal Agents; D005372:Filipin; D053038:Quorum Sensing; D064210:Secondary Metabolism; D013302:Streptomyces
Applied and environmental microbiology
2,020
D000935:Antifungal Agents; D005372:Filipin; D015107:4-Butyrolactone
Is the COVID-19 pandemic masking dengue epidemic in Bangladesh?
COVID-19 is now a pandemic. Like other countries, Bangladesh is putting all its efforts to combat this pandemic. Dengue is a mosquito-borne viral infection causing a severe flu-like illness and, sometimes causing a potentially lethal complication called severe dengue. At this very crisis moment, there are reports on ne...
10.5455/javar.2020.g412
32,607,352
Journal of advanced veterinary and animal research
2,020
The relationship of plasma estradiol and progesterone levels to the fatty liver hemorrhagic syndrome in laying hens.
The relationship of plasma estradiol and progesterone levels to fatty liver-hemorrhagic syndrome (FLHS) was studied with three groups of 9 White Leghorn hens per group. One group was fed ad libitum the other two group were force-fed at 120% and 135% of their own pre-experimental daily feed intake. Force-feeding for 3 w...
10.3382/ps.0602278
7,329,910
D000818:Animals; D002645:Chickens; D004958:Estradiol; D005234:Fatty Liver; D005260:Female; D006470:Hemorrhage; D011200:Poultry; D011201:Poultry Diseases; D011374:Progesterone; D013577:Syndrome
Poultry science
1,981
D011374:Progesterone; D004958:Estradiol
Effects of Tall Fescue Endophyte Type and Dopamine Receptor D2 Genotype on Cow-Calf Performance during Late Gestation and Early Lactation.
Grazing endophyte-infected, toxic tall fescue reduces cow/calf production; therefore, this study examines alternate strategies such as use of novel endophyte fescue varieties during late gestation and early lactation or genetic selection of resistant cows. Pregnant cows (n = 75) were randomly assigned to fescue endophy...
10.3390/toxins13030195
33,803,203
D000821:Animal Feed; D000818:Animals; D000833:Animals, Suckling; D001724:Birth Weight; D002417:Cattle; D060026:Endophytes; D004876:Ergot Alkaloids; D005260:Female; D005516:Food Microbiology; D005838:Genotype; D005865:Gestational Age; D000078064:Gestational Weight Gain; D060434:Herbivory; D007774:Lactation; D008129:Loli...
Toxins
2,021
D004876:Ergot Alkaloids; D017448:Receptors, Dopamine D2
Quantification and identification of microorganisms found on shell and kernel of fresh edible chestnuts in Michigan.
BACKGROUND Chestnut is a relatively new cultivated crop for Michigan, and postharvest loss due to decay has been problematic as production has increased each year. In 2007, more than 25% of chestnuts were lost to postharvest decay, equivalent to approximately 5300 kg of fresh product. To determine the organisms respons...
10.1002/jsfa.7667
26,869,338
D001203:Ascomycota; D001487:Basidiomycota; D020171:Botrytis; D000069599:Crop Production; D018556:Crops, Agricultural; D003433:Crosses, Genetic; D029962:Fagaceae; D005513:Food Inspection; D061353:Food Storage; D005658:Fungi; D006088:Gram-Negative Aerobic Bacteria; D006094:Gram-Positive Bacteria; D008824:Michigan; D05888...
Journal of the science of food and agriculture
2,016
A deuterium surface coil NMR study of the metabolism of D-methionine in the liver of the anesthetized rat.
The hepatic metabolism of deuteriated D-methionine has been studied in the intact, anesthetized rat using 2H NMR spectroscopy. The rate of formation of the principal labeled metabolite, [methyl-2H3]sarcosine, from the D-[methyl-2H3]methionine precursor was found to be as rapid as the rate observed previously in NMR stu...
10.1021/bi00420a042
2,462,910
D000818:Animals; D001565:Benzoates; D019817:Benzoic Acid; D003605:D-Amino-Acid Oxidase; D003903:Deuterium; D008099:Liver; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008715:Methionine; D051381:Rats; D011919:Rats, Inbred Strains; D012521:Sarcosine; D013237:Stereoisomerism
Biochemistry
1,988
D001565:Benzoates; D019817:Benzoic Acid; D008715:Methionine; D003903:Deuterium; D003605:D-Amino-Acid Oxidase; D012521:Sarcosine
Humanization of an agonistic anti-death receptor 4 single chain variable fragment antibody and avidity-mediated enhancement of its cell death-inducing activity.
Development of agonistic monoclonal antibodies (mAbs) against the pro-apoptotic molecule death receptor 4 (DR4) [or tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) receptor 1] is an attractive anti-cancer strategy because of their potential for inducing tumor-specific cell death. In this study, we...
10.1016/j.molimm.2009.09.041
19,864,027
D000595:Amino Acid Sequence; D000818:Animals; D000906:Antibodies; D000915:Antibody Affinity; D003602:Cytotoxicity, Immunologic; D045325:HCT116 Cells; D006801:Humans; D055767:Immobilized Proteins; D007128:Immunoglobulin Fragments; D007135:Immunoglobulin Variable Region; D007700:Kinetics; D051379:Mice; D008969:Molecular ...
Molecular immunology
2,010
D000906:Antibodies; D055767:Immobilized Proteins; D007128:Immunoglobulin Fragments; D007135:Immunoglobulin Variable Region; D053220:Receptors, TNF-Related Apoptosis-Inducing Ligand; D011993:Recombinant Fusion Proteins
The conserved Pelado/ZSWIM8 protein regulates actin dynamics by promoting linear actin filament polymerization.
Actin filament polymerization can be branched or linear, which depends on the associated regulatory proteins. Competition for actin monomers occurs between proteins that induce branched or linear actin polymerization. Cell specialization requires the regulation of actin filaments to allow the formation of cell type-spe...
10.26508/lsa.202201484
35,940,847
D008841:Actin Cytoskeleton; D000199:Actins; D000818:Animals; D003599:Cytoskeleton; D006801:Humans; D008322:Mammals; D058105:Polymerization; D011554:Pseudopodia; D044767:Ubiquitin-Protein Ligases
Life science alliance
2,022
D000199:Actins; D044767:Ubiquitin-Protein Ligases; C000713208:ZSWIM8 protein, human
Fasting limits the increase in intracellular calcium during ischemia in isolated rat hearts.
INTRODUCTION Fasting has been shown to limit ischemic injury and improve functional activity after global ischemia. Because calcium overload is considered a mechanism of ischemic injury, we hypothesized that fasting would limit the accumulation of intracellular calcium [Ca]i during ischemia, potentially due to reduced ...
10.1007/s003950170028
11,605,993
D000818:Animals; D001794:Blood Pressure; D002118:Calcium; D000252:Calcium-Transporting ATPases; D002614:Chelating Agents; D004533:Egtazic Acid; D005215:Fasting; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D017202:Myocardial Ischemia; D015428:Myocardial Reperfusion Injury; D009206:Myocardium; D...
Basic research in cardiology
2,001
D002614:Chelating Agents; D019831:Sodium-Calcium Exchanger; D004533:Egtazic Acid; C039877:5,5'-difluoro-1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid; D012964:Sodium; D000252:Calcium-Transporting ATPases; D000254:Sodium-Potassium-Exchanging ATPase; D002118:Calcium
Identifying optimal models to represent biochemical systems.
Biochemical systems involving a high number of components with intricate interactions often lead to complex models containing a large number of parameters. Although a large model could describe in detail the mechanisms that underlie the system, its very large size may hinder us in understanding the key elements of the ...
10.1371/journal.pone.0083664
24,416,170
D017360:Arabidopsis; D066246:ErbB Receptors; D035264:Flowers; D053263:Gene Regulatory Networks; D017343:Genes, Plant; D008954:Models, Biological; D015203:Reproducibility of Results; D049490:Systems Biology
PloS one
2,014
D066246:ErbB Receptors
Prevalence and clinical association of clonal T-cell expansions in Myelodysplastic Syndrome.
Selected patients with Myelodysplastic Syndromes (MDS) are responsive to immunosuppressive therapy, suggesting that hematopoietic suppressive T cells have a pathogenic role in ineffective hematopoiesis. We assessed T-cell receptor (TCR) clonality through combined flow cytometry and molecular analysis of the complementa...
10.1038/sj.leu.2404590
17,301,813
D015703:Antigens, CD; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes; D016133:Polymerase Chain Reaction; D011948:Receptors, Antigen, T-Cell; D013601:T-Lymphocytes; D050378:T-Lymphocytes, Regulatory
Leukemia
2,007
D015703:Antigens, CD; D011948:Receptors, Antigen, T-Cell
COVID-19 pandemic is an urgent time for older people to practice resistance exercise at home.
Social distancing measures have been used to contain the COVID-19 pandemic; nevertheless, it causes unintended greater time at home and consequently a reduction in general physical activity and an increase in sedentary time, which is harmful to older people. A decrease in daily physical activities and an increase in se...
10.1016/j.exger.2020.111101
33,049,354
D000368:Aged; D000369:Aged, 80 and over; D000086382:COVID-19; D006801:Humans; D018482:Muscle, Skeletal; D055070:Resistance Training; D000086402:SARS-CoV-2; D057185:Sedentary Behavior
Experimental gerontology
2,020
Antifungal activity, SAR and physicochemical correlation of some thiazole-1,3,5-triazine derivatives.
OBJECTIVE Present research communication was towards the investigation of antifungal minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) activity of some substituted clubbed thiazole-1,3,5-triazines derivatives and effect of physicochemical properties on bioactivity. MATERIAL AND METHODS...
10.1016/j.mycmed.2011.12.073
23,518,015
D000818:Animals; D000935:Antifungal Agents; D019306:Artemisia; D001234:Aspergillus niger; D002176:Candida albicans; D041221:Candida glabrata; D003455:Cryptococcus neoformans; D004353:Drug Evaluation, Preclinical; D007814:Larva; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D008970:Molecular Weight; ...
Journal de mycologie medicale
2,012
D000935:Antifungal Agents; D013844:Thiazoles; D014227:Triazines
Molecular and functional characterization of chicken interleukin 1 receptor 2 (chIL-1R2).
Interleukin-1 receptor type 2 (IL1R2) is a decoy receptor for exogenous IL-1. However, its functional role in chicken immunity is poorly understood. Herein, chicken IL-1R2 (chIL-1R2) was identified and functionally characterized in vivo and in vitro. The chIL-1R2 coding sequence includes 1,236 nucleotides encoding 412 ...
10.1016/j.psj.2022.102399
36,586,293
D000818:Animals; D002645:Chickens; D007378:Interleukins; D008322:Mammals; D020929:Mitogen-Activated Protein Kinase Kinases; D016328:NF-kappa B; D017472:Receptors, Interleukin-1; D053574:Receptors, Interleukin-1 Type II
Poultry science
2,023
D007378:Interleukins; D020929:Mitogen-Activated Protein Kinase Kinases; D016328:NF-kappa B; D017472:Receptors, Interleukin-1; D053574:Receptors, Interleukin-1 Type II
Gene transfer of heme oxygenase-1 and carbon monoxide delivery inhibit chronic rejection.
The hallmark of chronic rejection is the occlusion of the artery lumen by intima hyperplasia as a consequence of leukocyte infiltration and vascular smooth muscle cell (VSMC) migration and proliferation. Heme oxygenase-1 (HO-1) is a tissue protective molecule which degrades heme into carbon monoxide (CO), free iron and...
10.1034/j.1600-6143.2002.20702.x
12,201,358
D000818:Animals; D019556:COS Cells; D002248:Carbon Monoxide; D002263:Carboxyhemoglobin; D002522:Chlorocebus aethiops; D002908:Chronic Disease; D018014:Gene Transfer Techniques; D006084:Graft Rejection; D006419:Heme Oxygenase (Decyclizing); D051547:Heme Oxygenase-1; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; ...
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2,002
D002248:Carbon Monoxide; D002263:Carboxyhemoglobin; D006419:Heme Oxygenase (Decyclizing); D051547:Heme Oxygenase-1
Fluid mechanics of the left atrial ligation chick embryonic model of hypoplastic left heart syndrome.
Left atrial ligation (LAL) of the chick embryonic heart at HH21 is a model of the hypoplastic left heart syndrome (HLHS) disease, demonstrating morphological and hemodynamic features similar to human HLHS cases. Since it relies on mechanical intervention without genetic or pharmacological manipulations, it is a good mo...
10.1007/s10237-021-01447-3
33,774,755
D000818:Animals; D002642:Chick Embryo; D003198:Computer Simulation; D004195:Disease Models, Animal; D004699:Endocardium; D006325:Heart Atria; D006352:Heart Ventricles; D006439:Hemodynamics; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome; D007091:Image Processing, Computer-Assisted; D008955:Models, Cardiovascul...
Biomechanics and modeling in mechanobiology
2,021
Metabolic syndrome in Xinjiang Kazakhs and construction of a risk prediction model for cardiovascular disease risk.
BACKGROUND The high prevalence of metabolic syndrome (MetS) and cardiovascular diseases (CVD) is observed among Kazakhs in Xinjiang. Because MetS may significantly predict the occurrence of CVD, the inclusion of CVD-related indicators in metabolic network may improve the predictive ability for a CVD-risk model for Kaza...
10.1371/journal.pone.0202665
30,188,929
D000328:Adult; D019540:Area Under Curve; D002318:Cardiovascular Diseases; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome; D008875:Middle Aged; D012372:ROC Curve; D012307:Risk Factors
PloS one
2,018
A comparison of gradient capacity anion chromatography using macrocycles D-2.2.2 and D-2.2.1 in constant or variable temperature mode.
The ability of macrocyclic ligands to complex alkali metal cations has been exploited to perform chromatographic separations of anions. Macrocycles adsorbed to reversed phase columns can complex eluent cations, thus generating anion exchange sites. Gradient separations of anions can be performed by changing the column ...
10.1016/0039-9140(92)80273-g
18,965,473
Talanta
1,992
High genetic polymorphism among Giardia duodenalis isolates from Sahrawi children.
Human giardiasis, the gastrointestinal infection caused by two genetically different groups (or assemblages) of Giardia duodenalis, is very common worldwide, and its prevalence is higher in developing countries. However, few surveys in these regions have been performed to include a genetic characterization of the paras...
10.1016/j.trstmh.2009.04.017
19,477,474
D000293:Adolescent; D000462:Algeria; D000818:Animals; D002648:Child; D016054:DNA, Protozoan; D005243:Feces; D005260:Female; D016829:Giardia lamblia; D005873:Giardiasis; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
Transactions of the Royal Society of Tropical Medicine and Hygiene
2,009
D016054:DNA, Protozoan
Telomere length of subcutaneous adipose tissue cells is shorter in obese and formerly obese subjects.
Obesity and increased fat mass are associated with increased adipocyte proliferation. Telomere length can serve as a biomarker of a cell's biological (vs chronological) age. To gain insight in the physiology of adipose tissue, we aimed to investigate telomere length in subcutaneous adipose tissue in relation to age and...
10.1038/ijo.2010.49
20,231,841
D017667:Adipocytes; D016922:Cellular Senescence; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity; D050151:Subcutaneous Fat; D016615:Telomere
International journal of obesity (2005)
2,010
Solid lipid matrix mediated nanoarchitectonics for improved oral bioavailability of drugs.
Introduction: Solid matrix mediated lipid nanoparticle formulations (LNFs) retain some of the best features of ideal drug carriers necessary for improving the oral absorption and bioavailability (BA) of both hydrophilic and hydrophobic drugs. LNFs with solid matrices may be typically categorized into three major types ...
10.1080/17425255.2019.1621289
31,104,522
D000284:Administration, Oral; D000818:Animals; D001682:Biological Availability; D004337:Drug Carriers; D016503:Drug Delivery Systems; D004355:Drug Stability; D006801:Humans; D008055:Lipids; D053758:Nanoparticles; D010539:Permeability; D004364:Pharmaceutical Preparations; D012995:Solubility
Expert opinion on drug metabolism & toxicology
2,019
D004337:Drug Carriers; D008055:Lipids; D004364:Pharmaceutical Preparations
Improved cytosolic delivery of macromolecules through dimerization of attenuated lytic peptides.
Intracellular delivery of biomacromolecules is a challenging research field in chemical biology and drug delivery. We previously reported a peptide named L17E, which successfully delivered functional proteins, including antibodies, into cells. However, relatively high concentrations of L17E and proteins are needed. In ...
10.1016/j.bmcl.2020.127362
32,738,963
D000595:Amino Acid Sequence; D000906:Antibodies; D003600:Cytosol; D019281:Dimerization; D004337:Drug Carriers; D005456:Fluorescent Dyes; D006367:HeLa Cells; D006801:Humans; D018613:Microscopy, Confocal; D010455:Peptides
Bioorganic & medicinal chemistry letters
2,020
D000906:Antibodies; D004337:Drug Carriers; D005456:Fluorescent Dyes; D010455:Peptides
Impact of a trained vascular access coordinator on a vascular access program in India.
BACKGROUND Native AV fistulas are the ideal access for hemodialysis but require monitoring and multiple interventions in some patients to keep them functioning. The aim of the study was to assess the impact of the appointment of a trained vascular access coordinator (VAC) for fistula monitoring, on the evolution of the...
10.1177/11297298211001612
33,719,702
D001164:Arteriovenous Fistula; D001166:Arteriovenous Shunt, Surgical; D006083:Graft Occlusion, Vascular; D006801:Humans; D006435:Renal Dialysis; D012189:Retrospective Studies; D016896:Treatment Outcome; D014654:Vascular Patency
The journal of vascular access
2,022
A case study of flood frequency analysis by intercomparison of graphical linear log-regression method and Gumbel's analytical method in the Vaigai river basin of Tamil Nadu, India.
Flood Frequency Analysis (FFA) is a systematic tool used for an efficient hydraulic structures design, operation and maintenance. An effort is made to study and compare the Linear Log Regression Graphical Method (LLRGM) and Gumbel's Analytical Method (GAM) to assess the future flood magnitude for any given Return Perio...
10.1016/j.chemosphere.2021.131571
34,293,571
D055868:Floods; D005544:Forecasting; D007194:India; D012044:Regression Analysis; D045483:Rivers
Chemosphere
2,022
Prospective evaluation of in vivo and phantom repeatability and reproducibility of diffusion-weighted MRI sequences on 1.5 T MRI-linear accelerator (MR-Linac) and MR simulator devices for head and neck cancers.
INTRODUCTION Diffusion-weighted imaging (DWI) on MRI-linear accelerator (MR-linac) systems can potentially be used for monitoring treatment response and adaptive radiotherapy in head and neck cancers (HNC) but requires extensive validation. We performed technical validation to compare six total DWI sequences on an MR-l...
10.1016/j.radonc.2023.109717
37,211,282
D006801:Humans; D015203:Reproducibility of Results; D008279:Magnetic Resonance Imaging; D038524:Diffusion Magnetic Resonance Imaging; D006258:Head and Neck Neoplasms; D017352:Echo-Planar Imaging
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
2,023
Comprehensive transcriptome analysis of faba bean in response to vernalization.
This study unravels the transcriptional response of a highly productive faba bean cultivar under vernalization treatment. Faba bean (Vicia faba L.) is a member of the Leguminosae family and an important food crop worldwide providing valuable nutrients for humans. However, genome-wide studies and comprehensive sequencin...
10.1007/s00425-019-03308-x
31,781,953
D003080:Cold Temperature; D035264:Flowers; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D063990:Gene Ontology; D017343:Genes, Plant; D053858:Metabolic Networks and Pathways; D018895:Microsatellite Repeats; D058977:Molecular Sequence Annotation; D012333:RNA, Messenger; D036226:Seedlings;...
Planta
2,019
D012333:RNA, Messenger; D014157:Transcription Factors
Gay Circuit Parties in Barcelona and Their Impact on Gonorrhea Incidence.
This study explored the role of circuit parties on the incidence of gonorrhea among men who have sex with men (MSM) in Barcelona (Spain). Specifically, it aimed to detect cyclic peaks in the number of reported diagnoses of gonorrhea after gay circuit parties. We analyzed monthly cases of gonorrhea reported from January...
10.1007/s10508-018-1220-9
30,014,338
D000328:Adult; D017280:Condoms; D005260:Female; D006069:Gonorrhea; D020010:Heterosexuality; D018451:Homosexuality, Male; D006801:Humans; D015994:Incidence; D008297:Male; D012725:Sexual Behavior; D000072339:Sexual and Gender Minorities; D012749:Sexually Transmitted Diseases; D013030:Spain; D014505:Urban Population
Archives of sexual behavior
2,018
Disease misclassification in electronic healthcare database studies: Deriving validity indices-A contribution from the ADVANCE project.
There is a strong and continuously growing interest in using large electronic healthcare databases to study health outcomes and the effects of pharmaceutical products. However, concerns regarding disease misclassification (i.e. classification errors of the disease status) and its impact on the study results are legitim...
10.1371/journal.pone.0231333
32,320,422
D000465:Algorithms; D016208:Databases, Factual; D004194:Disease; D057286:Electronic Health Records; D006801:Humans; D014584:User-Computer Interface
PloS one
2,020
Electron diffraction from single crystals of DNA.
Crystals of DNA have been grown in a form suitable for study by electron diffraction and electron microscopy. Preliminary electron diffraction patterns of any type that have been obtained from single crystals of highly polymerized DNA. The patterns, obtained from frozen, hydrated crystals with the beam approximately pa...
10.1016/S0006-3495(80)85020-X
7,260,304
D000818:Animals; D002417:Cattle; D003460:Crystallization; D004247:DNA; D008854:Microscopy, Electron; D009690:Nucleic Acid Conformation; D013950:Thymus Gland
Biophysical journal
1,980
D004247:DNA
Knowledge, Attitude and Practice of healthcare workers Towards Coronavirus Disease 2019 (COVID-19) Pandemic.
BACKGROUND The emergence of SARS-CoV 2 pandemic is the greatest public health concern of the century. Healthcare workers are the front liners of pandemic management. Their knowledge, attitudes and practices can influence the outcome of pandemic. The study aims to determine the knowledge, attitude and practices among he...
10.33314/jnhrc.v18i2.2658
32,969,396
D000328:Adult; D000073640:Betacoronavirus; D000086382:COVID-19; D018352:Coronavirus Infections; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006282:Health Personnel; D006801:Humans; D017053:Infection Control; D008297:Male; D009390:Nepal; D058873:Pandemics; D000067393:Personal Protective Equipment; D0...
Journal of Nepal Health Research Council
2,020
Intestinal parasitic infections and risk factors: a cross-sectional survey of some school children in a suburb in Accra, Ghana.
OBJECTIVE This study aimed to determine the prevalence and establish some risk factors associated with the acquisition of gastrointestinal parasitic infections in school children in Accra, Ghana. RESULTS The overall prevalence of intestinal parasitic infection was 15%. Giardia lamblia (10%) and Schistosoma mansoni (1...
10.1186/s13104-017-2802-7
28,923,091
D000818:Animals; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003710:Demography; D005260:Female; D005869:Ghana; D006801:Humans; D007411:Intestinal Diseases, Parasitic; D008297:Male; D010271:Parasites; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population
BMC research notes
2,017
Palmitoleate Reverses High Fat-induced Proinflammatory Macrophage Polarization via AMP-activated Protein Kinase (AMPK).
A rise in tissue-embedded macrophages displaying "M1-like" proinflammatory polarization is a hallmark of metabolic inflammation during a high fat diet or obesity. Here we show that bone marrow-derived macrophages (BMDM) from high fat-fed mice retain a memory of their dietary environment in vivo (displaying the elevated...
10.1074/jbc.M115.646992
25,987,561
D055372:AMP-Activated Protein Kinases; D000818:Animals; D016764:Cell Polarity; D059305:Diet, High-Fat; D004041:Dietary Fats; D005229:Fatty Acids, Monounsaturated; D006801:Humans; D008264:Macrophages; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009765:Obesity
The Journal of biological chemistry
2,015
D004041:Dietary Fats; D005229:Fatty Acids, Monounsaturated; C008757:palmitoleic acid; D055372:AMP-Activated Protein Kinases
Scattered dose to gonads and associated risks from radiotherapy for common pediatric malignancies : a phantom study.
PURPOSE To measure the scattered dose to ovaries and testes from radiotherapy for common pediatric malignancies and to assess the relevant risks for radiation-induced gonadal damage and hereditary disorders in future generations. MATERIAL AND METHODS Radiotherapy for central nervous system tumors, acute leukemia, neu...
10.1007/s00066-007-1653-x
17,520,188
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms; D010053:Ovary; D011832:Radiation Injuries; D018570:Risk Assessment; D012542:Scattering, Radiation; D013737:Testis; D013819:Thermoluminescent Dosimetry
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
2,007
Divalent germanium compound with a radical-anionic ligand: molecular structures of (dpp-BIAN)*- GeCl and its hydrochloration products [(dpp-BIAN)(H)2]*+ [GeCl3]- and [[(dpp-BIAN)(H)2*+]2(Cl-)]+ [GeCl3]- (dpp-BIAN=1,2-Bis[(2,6-diisopropylphenyl)imino]acenaphthene).
The germanium(II) compound (dpp-BIAN)GeCl (1), which contains the radical anion of dpp-BIAN can be prepared either by reacting free dpp-BIAN ligand with 2 equiv of GeCl2(1,4-dioxane) in Et2O or by metathetical reaction of the sodium salt of dpp-BIAN with germanium dichloride in Et2O or benzene. The reaction of benzene ...
10.1021/ic048801g
15,554,646
Inorganic chemistry
2,004
[The most common heart valve diseases: aortic stenosis and mitral regurgitation. A few comments on guidelines and recommendations by societies of cardiology].
Recommendations of professional societies, frequently called guidelines as per the English translation, provide help to the general practice as well as specialized physicians. These are recommendations, not a legislative norm. Societies of cardiology have issued 3 new guidelines over the recent years; American ACC/AHA ...
19,785,376
D001024:Aortic Valve Stenosis; D006801:Humans; D008944:Mitral Valve Insufficiency; D017410:Practice Guidelines as Topic; D012955:Societies, Medical
Vnitrni lekarstvi
2,009
Effect of element size on stereoscopic apparent motion.
Spatial displacement limits in stereoscopic (cyclopean) apparent motion were measured from sequentially presented two-frame random-depth configurations. Each depth configuration was defined by stereoscopically near or far elements of various sizes. The limits were compared with those in luminance-defined apparent motio...
10.2466/pms.2003.96.3c.1187
12,929,772
D003867:Depth Perception; D006801:Humans; D008027:Light; D009039:Motion Perception; D011897:Random Allocation; D012858:Size Perception; D013028:Space Perception
Perceptual and motor skills
2,003
Nonunion of fractures of the subtrochanteric region of the femur.
There are no large clinical series to guide the clinician treating a subtrochanteric nonunion. Deformity, bone loss from previous hardware, and the high stresses in the subtrochanteric region all pose challenges to achieving successful bony union with reoperation. The purpose of this study was to retrospectively review...
10.1097/00003086-200402000-00030
15,021,152
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001858:Bone Nails; D001860:Bone Plates; D015331:Cohort Studies; D005260:Female; D005264:Femoral Fractures; D005594:Fracture Fixation, Intramedullary; D017102:Fracture Healing; D005599:Fractures, Ununited; D006620:Hip Fractures; D006801:Humans;...
Clinical orthopaedics and related research
2,004
Far-lateral transcondylar approach: surgical technique and its application in neurenteric cysts of the cervicomedullary junction. Report of two cases.
Neurenteric cysts are rare benign lesions of the central nervous system that are lined by endodermal cell-derived epithelium. Although they occur mostly in the spine, they can occur intracranially, most often in the posterior fossa. Neurenteric cysts that are located in the anterior cervicomedullary junction are even r...
10.3171/foc.2005.19.2.10
16,122,218
D000328:Adult; D002574:Cervical Vertebrae; D005260:Female; D006801:Humans; D008526:Medulla Oblongata; D008875:Middle Aged; D009436:Neural Tube Defects; D019635:Neurosurgical Procedures
Neurosurgical focus
2,005
MicroRNAs control transcription factor NF-kB (p65) expression in human ovarian cells.
MicroRNAs (miRNAs) are known to influence ovarian cell proliferation, apoptosis and hormone release, but it remains unknown whether miRNAs affect ovarian functions via transcription factors. We examined the effect of miRNAs on nuclear factor-κappaB (NF-kB) (p65) expression in human ovarian luteinized granulosa cells. W...
10.1007/s10142-014-0413-0
25,403,593
D000328:Adult; D002470:Cell Survival; D002478:Cells, Cultured; D005260:Female; D006107:Granulosa Cells; D006801:Humans; D035683:MicroRNAs; D051996:Transcription Factor RelA; D014162:Transfection
Functional & integrative genomics
2,015
D035683:MicroRNAs; D051996:Transcription Factor RelA
Evaluation of fertilizer-drawn forward osmosis for sustainable agriculture and water reuse in arid regions.
The present study focused on the performance of the FDFO process to achieve simultaneous water reuse from wastewater and production of nutrient solution for hydroponic application. Bio-methane potential (BMP) measurements were firstly carried out to determine the effect of osmotic concentration of wastewater achieved i...
10.1016/j.jenvman.2016.11.021
27,889,657
D000383:Agriculture; D000645:Ammonium Sulfate; D003247:Conservation of Natural Resources; D005308:Fertilizers; D018527:Hydroponics; D008567:Membranes, Artificial; D008697:Methane; D009995:Osmosis; D010710:Phosphates; D017680:Potassium Compounds; D059027:Recycling; D012996:Solutions; D062065:Wastewater; D018508:Water Pu...
Journal of environmental management
2,017
D005308:Fertilizers; D008567:Membranes, Artificial; D010710:Phosphates; D017680:Potassium Compounds; D012996:Solutions; D062065:Waste Water; C024788:ammonium phosphate; C013216:potassium phosphate; D008697:Methane; D000645:Ammonium Sulfate
Factors affecting consultant attitudes to undertaking undergraduate medical student teaching in the UK: a systematic review.
OBJECTIVE This systematic review aimed to explore consultant attitudes towards teaching undergraduate medical students in the UK. DESIGN Systematic review. METHODOLOGY Standard systematic review methodology was followed. MEDLINE, EMBASE and OpenGrey were searched from inception to August 2019 to identify studies ex...
10.1136/bmjopen-2020-042653
33,419,916
D001291:Attitude of Health Personnel; D003253:Consultants; D004504:Education, Medical, Undergraduate; D006801:Humans; D013337:Students, Medical; D013663:Teaching; D006113:United Kingdom
BMJ open
2,021
Predictive value of negative initial postoperative imaging after endovascular aortic aneurysm repair.
OBJECTIVE The risk of endoleak and reintervention after endovascular abdominal aortic aneurysm repair necessitates lifelong surveillance, which has associated costs, radiation exposure, and risk of nephrotoxicity. The best imaging method and timing of surveillance remain controversial. We sought to determine if a negat...
24,726,829
D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal; D001027:Aortography; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation; D016009:Chi-Square Distribution; D057867:Endoleak; D057510:Endovascular Procedures; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male...
Journal of vascular surgery
2,014
[Investigation of anti-Leishmania seroprevalence by different serologic assays in children inhabiting in the northwestern part of Turkey].
Human visceral leishmaniasis (VL) caused by Leishmania infantum in Mediterranean region is still an important public health problem in those countries including Turkey. The asymptomatic presentation of the infection in most of the cases leads to difficulties in the diagnosis and prevention of the spread of infection. T...
18,444,567
D000293:Adolescent; D000818:Animals; D000913:Antibodies, Protozoan; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007223:Infant; D018314:Leishmania infantum; D007898:Leishmaniasis, Visceral; D008297:...
Mikrobiyoloji bulteni
2,008
D000913:Antibodies, Protozoan
Laparoscopic Transgastric Resection of a Large Gastric GIST: A Case Report and Review of Literature.
Introduction  Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal (GI) tract. Their primary treatment is surgical. Case Report  Here we report a case of a 36-year-old male patient who was being evaluated for weakness, anemia, and melena. Upper GI endoscopy showed a mass...
10.1055/s-0041-1739116
34,934,813
Surgery journal (New York, N.Y.)
2,021
Impact of Genomic and Clinical Factors on Outcome of Children ≥18 Months of Age with Stage 3 Neuroblastoma with Unfavorable Histology and without MYCN Amplification: A Children's Oncology Group (COG) Report.
PURPOSE Patients ≥18 months of age with International Neuroblastoma Staging System (INSS) stage 3 unfavorable histology (UH), MYCN-nonamplified (MYCN-NA) tumors have favorable survival rates compared with other high-risk neuroblastoma populations. The impact of select clinical and biological factors on overall survival...
10.1158/1078-0432.CCR-22-3032
36,749,880
D006801:Humans; D002648:Child; D007223:Infant; D009367:Neoplasm Staging; D000071447:N-Myc Proto-Oncogene Protein; D009447:Neuroblastoma; D016259:Genes, myc; D002872:Chromosome Deletion; D023281:Genomics; D005784:Gene Amplification; D011379:Prognosis
Clinical cancer research : an official journal of the American Association for Cancer Research
2,023
D000071447:N-Myc Proto-Oncogene Protein; C459801:MYCN protein, human
High-transmission and large group delay terahertz triple-band electromagnetically induced transparency in a metal-perovskite hybrid metasurface.
A high-transmission and large group delay terahertz triple-band electromagnetically induced transparency (EIT) effect is obtained in a metal-perovskite hybrid metasurface, which consists of a cross metal (CM), a pair of square metal frames (SMFs), and a pair of square split rings (SSRs). The results reveal that the tra...
10.1039/d3cp03072e
37,545,399
Physical chemistry chemical physics : PCCP
2,023
Neuroimmune Crosstalk Between the Peripheral and the Central Immune System in Amyotrophic Lateral Sclerosis.
Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by the degeneration and death of motor neurons. Systemic neuroinflammation contributes to the pathogenesis of ALS. The proinflammatory milieu depends on the continuous crosstalk between the peripheral immune system (PIS) and central immune system (CIS...
10.3389/fnagi.2022.890958
35,592,701
Frontiers in aging neuroscience
2,022
Modulation of keratinocyte growth factor and its receptor in reepithelializing human skin.
We investigated the expression and distribution of keratinocyte growth factor (KGF) (FGF-7) and its receptor (KGFR) during reepithelialization of human skin. KGF mRNA levels increased rapidly by 8-10-fold and remained elevated for several days. In contrast, KGFR transcript levels decreased early but were significantly ...
10.1084/jem.182.5.1369
7,595,207
D000328:Adult; D002454:Cell Differentiation; D015536:Down-Regulation; D004817:Epidermis; D051526:Fibroblast Growth Factor 10; D051523:Fibroblast Growth Factor 7; D005346:Fibroblast Growth Factors; D005786:Gene Expression Regulation; D005803:Genes, Immunoglobulin; D006133:Growth Substances; D006801:Humans; D008875:Middl...
The Journal of experimental medicine
1,995
C496453:FGF7 protein, human; D051526:Fibroblast Growth Factor 10; D006133:Growth Substances; D012333:RNA, Messenger; D017468:Receptors, Fibroblast Growth Factor; D017978:Receptors, Growth Factor; D011993:Recombinant Fusion Proteins; D051523:Fibroblast Growth Factor 7; D013498:Suramin; D005346:Fibroblast Growth Factors;...
Tetrahydrocarbazole amides with potent activity against human papillomaviruses.
Synthesis of a series of tetrahydrocarbazole amides with potent activity against human papillomaviruses is described. Synthetic approaches allowing for variation of the substitution pattern of the tetrahydrocarbazole and the amide are outlined and resulting changes in antiviral activity and certain developability param...
10.1016/j.bmcl.2009.06.001
19,556,128
D000284:Administration, Oral; D000577:Amides; D000818:Animals; D000998:Antiviral Agents; D002227:Carbazoles; D002522:Chlorocebus aethiops; D003577:Cytochrome P-450 Enzyme System; D004285:Dogs; D000882:Haplorhini; D006801:Humans; D020128:Inhibitory Concentration 50; D008956:Models, Chemical; D027383:Papillomaviridae; D0...
Bioorganic & medicinal chemistry letters
2,009
D000577:Amides; D000998:Antiviral Agents; D002227:Carbazoles; D003577:Cytochrome P-450 Enzyme System
Experiences of nurse leaders surviving Hurricane Katrina, New Orleans, Louisiana, USA.
Hurricane Katrina left New Orleans, Louisiana, USA destroyed by its impact on 29 August 2005. Working during a hurricane was nothing new to these authors. Having lived in New Orleans all our lives, we were used to preparing our homes and our families to weather the storm. Nurses are in leadership positions before, duri...
10.1111/j.1442-2018.2009.00497.x
20,487,319
D055867:Cyclonic Storms; D004189:Disaster Planning; D004190:Disasters; D005260:Female; D006801:Humans; D008145:Louisiana; D008297:Male; D055820:New Orleans; D024802:Nurse's Role; D009741:Nursing Staff, Hospital; D009745:Nursing, Supervisory; D016272:Occupational Health; D012066:Relief Work; D018635:Rescue Work; D018570...
Nursing & health sciences
2,010
Stress Hyperglycemia, Diabetes Mellitus and COVID-19 Infection: Risk Factors, Clinical Outcomes and Post-Discharge Implications.
The novel severe acute respiratory distress syndrome-coronavirus 2 (SARS-CoV-2) has caused one of the most substantial pandemics that has affected humanity in the last century. At the time of the preparation of this review, it has caused the death of around 5 million people around the globe. There is ample evidence lin...
10.3389/fcdhc.2022.826006
36,992,767
Frontiers in clinical diabetes and healthcare
2,022
How essentialist reasoning about language acquisition relates to educational myths and policy endorsements.
How people conceptualize learning is related to real-world educational consequences across many domains of education. Despite its centrality to the educational system, we know little about how the public reasons about language acquisition, and the potential consequences for their thinking about real-world issues (e.g.,...
10.1186/s41235-023-00481-2
37,145,210
D006801:Humans; D007802:Language; D019303:Multilingualism; D007804:Language Development; D007858:Learning; D001921:Brain
Cognitive research: principles and implications
2,023
An uncommon presentation of acute type A aortic dissection: left main coronary artery obstruction.
Acute aortic dissection presents with a wide range of manifestations. Sometimes an acute coronary syndrome is diagnosed instead of aortic dissection leading to inappropriate treatment. We describe a case of acute aortic dissection with the uncommon involvement of the left main coronary artery. A 64-year-old man was ref...
10.2459/JCM.0b013e328348c390
21,670,701
D000208:Acute Disease; D000784:Aortic Dissection; D001018:Aortic Diseases; D001027:Aortography; D017023:Coronary Angiography; D003324:Coronary Artery Disease; D017548:Echocardiography, Transesophageal; D004562:Electrocardiography; D017809:Fatal Outcome; D006323:Heart Arrest; D006801:Humans; D008297:Male; D008875:Middle...
Journal of cardiovascular medicine (Hagerstown, Md.)
2,012
Comparison of 25-gauge, Quincke and Whitacre needles for postdural puncture headache in obstetric patients.
OBJECTIVE To compare the frequency of postdural puncture headache (PDPH) and failure rate of spinal anesthesia using 25-gauge Quincke and 25-gauge Whitacre needles in obstetric patients. DESIGN Single blinded, interventional experimental study. PLACE AND DURATION OF STUDY This study was conducted at the Department ...
11.2004/JCPSP.647650
15,530,271
D000293:Adolescent; D000328:Adult; D000775:Anesthesia, Spinal; D002585:Cesarean Section; D005260:Female; D006261:Headache; D006801:Humans; D009339:Needles; D016602:Needlestick Injuries; D010154:Pakistan; D011247:Pregnancy; D016037:Single-Blind Method; D017211:Treatment Failure
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
2,004
Effects of Materialism on Adolescents' Prosocial and Aggressive Behaviors: The Mediating Role of Empathy.
Materialism plays a critical role in adolescent behavioral development, yet whether it affects prosocial and aggressive behaviors and the internal mechanism remains unknown. Therefore, this longitudinal research examined the relationships between adolescent materialism and prosocial and aggressive behaviors, and tested...
10.3390/bs13100863
37,887,513
Behavioral sciences (Basel, Switzerland)
2,023
A Novel Method for Mendelian Randomization Analyses With Pleiotropy and Linkage Disequilibrium in Genetic Variants From Individual Data.
Mendelian randomization makes use of genetic variants as instrumental variables to eliminate the influence induced by unknown confounders on causal estimation in epidemiology studies. However, with the soaring genetic variants identified in genome-wide association studies, the pleiotropy, and linkage disequilibrium in ...
10.3389/fgene.2021.634394
34,322,150
Frontiers in genetics
2,021
Epidemiology and outcomes of primary pediatric lung malignancies: Updates from the SEER database.
BACKGROUND Primary pediatric lung malignancies are rare tumors. We provide an updated analysis of the epidemiology and prognosis of these tumors since the last SEER series published in 2009. METHODS The SEER 18 database from 1975 to 2016 was analyzed for patients ages 0-19 years with primary lung and/or bronchus neop...
10.1016/j.amjsurg.2021.01.037
33,549,297
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003710:Demography; D005260:Female; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D018426:SEER Program; D015996:Survival Rate; D014481:United States
American journal of surgery
2,021
Measurement of lateral adhesion forces at the interface between a liquid drop and a substrate.
A novel instrument allows for the first time measurements of the lateral adhesion forces at a solid-liquid interface, f(parallel), in a way that is decoupled from the normal forces, f(perpendicular). We use it to measure how f(parallel) between a drop and a surface is influenced by different f(perpendicular) and differ...
10.1103/PhysRevLett.103.266101
20,366,322
Physical review letters
2,009
Effects of engineered cerium oxide nanoparticles on bacterial growth and viability.
Interest in engineered nanostructures has risen in recent years due to their use in energy conservation strategies and biomedicine. To ensure prudent development and use of nanomaterials, the fate and effects of such engineered structures on the environment should be understood. Interactions of nanomaterials with envir...
10.1128/AEM.00650-10
20,952,651
D000900:Anti-Bacterial Agents; D001412:Bacillus subtilis; D002563:Cerium; D015169:Colony Count, Microbial; D003470:Culture Media; D004926:Escherichia coli; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests; D050296:Microbial Viability; D053758:Nanoparticles; D010316:Particle Size; D020592:Shewanel...
Applied and environmental microbiology
2,010
D000900:Anti-Bacterial Agents; D003470:Culture Media; D002563:Cerium; C030583:ceric oxide
Superelastic cage implantation: a new technique for treating osteonecrosis of the femoral head with mid-term follow-ups.
We developed a device for the treatment of Ficat and Arlet stage II and III osteonecrosis of the femoral head. This device, which we named the "super-elastic cage," was designed to provide mechanical support for the necrotic weight-bearing area of the femoral head to prevent its collapse. The cage was used in combinati...
10.1016/j.arth.2008.07.010
18,848,424
D000328:Adult; D016025:Bone Transplantation; D004864:Equipment and Supplies; D005260:Female; D005271:Femur Head Necrosis; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D009983:Orthopedic Equipment; D019637:Orth...
The Journal of arthroplasty
2,009
Gas-chromatographic analyses of the subcaudal gland secretion of the European badger (Meles meles) part II: time-related variation in the individual-specific composition.
Individuality in body odors has been described in a variety of species, but studies on time-related variation in individual scent are scarce. Here, we use GC-MS to investigate how chemical composition of subcaudal gland secretions of European badgers (Meles meles) varies over days, seasons, and from year to year, and h...
10.1023/a:1013510802127
11,868,679
D000818:Animals; D002335:Carnivora; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D008297:Male; D012543:Scent Glands; D012621:Seasons
Journal of chemical ecology
2,002
Subclinical hypothyroidism and the risk of metabolic syndrome: A meta-analysis of observational studies.
BACKGROUND Observational studies on the association between subclinical hypothyroidism (SCH) and metabolic syndrome (MetS) have produced inconsistent results. Therefore, we performed a meta-analysis to evaluate the effect of SCH on the risk of MetS. METHODS Multiple databases were searched to identify studies on the ...
10.3109/07435800.2015.1108332
26,934,475
D015897:Comorbidity; D006801:Humans; D007037:Hypothyroidism; D024821:Metabolic Syndrome; D064887:Observational Studies as Topic
Endocrine research
2,016
Fictibacillus marinisediminis sp. nov., a nitrate-reducing bacterium isolated from marine sediment in Hupo Basin, Republic of Korea.
An isolate, designated strain KIGAM418T was isolated from marine mud below 192 m depth in the Hupo Basin, Republic of Korea. Strain KIGAM418T was Gram-stain positive, spore-forming, rod-shaped, facultatively anaerobic, and grew at 10‒45 °C, in 0‒2% (w/v) NaCl at pH 4.0‒12.0. The strain tested positive for catalase, oxi...
10.1007/s00203-022-03067-6
35,829,821
D015373:Bacterial Typing Techniques; D004269:DNA, Bacterial; D005227:Fatty Acids; D019015:Geologic Sediments; D009566:Nitrates; D010743:Phospholipids; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S; D017422:Sequence Analysis, DNA
Archives of microbiology
2,022
D004269:DNA, Bacterial; D005227:Fatty Acids; D009566:Nitrates; D010743:Phospholipids; D012336:RNA, Ribosomal, 16S
The recurrent laryngeal nerve: related vascular anatomy.
This study was based on 34 recurrent laryngeal nerve dissections after arterial casting with red-colored latex. The aim was to provide specific information about the perineural microvasculature. This study established the following points: 1. a great anatomic variability does exist; 2. the laryngeal nerve is usually in...
10.1097/00005537-199809000-00017
9,738,755
D002102:Cadaver; D049669:History, 16th Century; D006801:Humans; D007823:Laryngeal Nerves
The Laryngoscope
1,998
Rapid microwave synthesis of MOF microrods: Dispersive SPE coupled with UHPLC-MS/MS to determine fluoroquinolones in honey.
A novel sorbent Cu-S metal-organic framework (MOF) microrods was prepared for dispersive solid-phase extraction via microwave synthesis and used to determine 12 fluoroquinolones (FQs) in honey samples employing ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). The best extraction effic...
10.1016/j.talanta.2023.124733
37,247,453
D024841:Fluoroquinolones; D002851:Chromatography, High Pressure Liquid; D000073396:Metal-Organic Frameworks; D053719:Tandem Mass Spectrometry; D006722:Honey; D008872:Microwaves; D052616:Solid Phase Extraction
Talanta
2,023
D024841:Fluoroquinolones; D000073396:Metal-Organic Frameworks
Milestoning without a Reaction Coordinate.
Milestoning is a method for calculating kinetics and thermodynamics of long time processes typically not accessible for straightforward Molecular Dynamics (MD) simulation. In the Milestoning approach, the system of interest is partitioned into cells by dividing hypersurfaces (Milestones) and transitions are computed be...
10.1021/ct100114j
20,596,240
Journal of chemical theory and computation
2,010
[The significance of speaking for the transfer of bacteria, and of the tuberculin skin test for the diagnosis of tuberculosis (author's transl)].
A Korean nurse was employed in Germany after having passed the routine medical checkup without discovery of apparent disease. Five months later she fell ill with fever due to pneumonia. Work was suspended for 8 days and then continued in an infants' ward for another 8 weeks. Because of increasing weakness the nurse was...
1,219,479
D005260:Female; D005860:Germany, West; D007723:Korea; D008403:Mass Screening; D013060:Speech; D014374:Tuberculin Test; D014397:Tuberculosis, Pulmonary
Monatsschrift fur Kinderheilkunde
1,975
Concomitant deregulation of HIF1alpha and cell cycle proteins in VHL-mutated renal cell carcinomas.
Renal cell carcinomas (RCCs) of the clear cell type are associated with alteration of the von Hippel-Lindau (VHL) tumour suppressor gene as well as subsequent stabilization and over-expression of hypoxia inducible factor (HIF), which causes up-regulation of cyclin D1. On the basis of their ability to interact with cycl...
10.1007/s00428-005-1262-y
15,991,006
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell; D018797:Cell Cycle Proteins; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms; D008297:Male; D008875:Middle Aged; D009154:Mutation; D012333:RNA, Messenger; D020133:Reverse Transcriptase Polymeras...
Virchows Archiv : an international journal of pathology
2,005
D018797:Cell Cycle Proteins; D012333:RNA, Messenger; D051794:Von Hippel-Lindau Tumor Suppressor Protein; C497446:VHL protein, human
Observational study of the epidemiology and outcomes of vancomycin-resistant Enterococcus bacteraemia treated with newer antimicrobial agents.
Vancomycin-resistant Enterococcus bloodstream infections (VRE-BSI) are a growing problem with few clinical trials to guide therapy. We conducted a retrospective study of management and predictors of mortality for VRE-BSI at a tertiary-care centre from January 2005 to August 2008. Univariate and multivariable analyses e...
10.1017/S0950268810002475
21,073,764
D000081:Acetamides; D000368:Aged; D000890:Anti-Infective Agents; D016470:Bacteremia; D017576:Daptomycin; D016983:Enterococcus; D005260:Female; D016908:Gram-Positive Bacterial Infections; D006801:Humans; D000069349:Linezolid; D008297:Male; D008875:Middle Aged; D023303:Oxazolidinones; D012189:Retrospective Studies; D0207...
Epidemiology and infection
2,011
D000081:Acetamides; D000890:Anti-Infective Agents; D023303:Oxazolidinones; D000069349:Linezolid; D017576:Daptomycin
Antibody-Drug Conjugates as Cancer Therapeutics: Past, Present, and Future.
Antibody-drug conjugates (ADCs) represent an innovative therapeutic approach that provides novel treatment options and hope for patients with cancer. By coupling monoclonal antibodies (mAbs) to cytotoxic small-molecule payloads with a plasma-stable linker, ADCs offer the potential for increased drug specificity and few...
10.1002/jcph.981
28,921,650
D000818:Animals; D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents; D015195:Drug Design; D006801:Humans; D018796:Immunoconjugates; D009369:Neoplasms
Journal of clinical pharmacology
2,017
D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents; D018796:Immunoconjugates
Differences in Parent-Toddler Interactions With Electronic Versus Print Books.
OBJECTIVES Previous research has documented less dialogic interaction between parents and preschoolers during electronic-book reading versus print. Parent-toddler interactions around commercially available tablet-based books have not been described. We examined parent-toddler verbal and nonverbal interactions when read...
10.1542/peds.2018-2012
30,910,918
D000328:Adult; D001877:Books; D002675:Child, Preschool; D004581:Electronics; D005260:Female; D006801:Humans; D008297:Male; D010287:Parent-Child Relations; D011327:Printing; D011932:Reading; D011795:Surveys and Questionnaires; D014481:United States; D014706:Verbal Learning
Pediatrics
2,019
Nitrate sources and transformations along a mountain-to-plain gradient in the Taizi River basin in Northeast China.
Fifty-seven riverine samples in three typical regions, namely, upper mountainous (zone 1), middle hilly (zone 2), and lower plain (zone 3) regions, were collected in May (low flow) and August (high flow) of 2016, and chemical parameters and isotopes were analyzed to enrich the knowledge of riverine nitrate sources and ...
10.1007/s11356-021-14762-0
34,115,303
D001499:Bayes Theorem; D002681:China; D004784:Environmental Monitoring; D009566:Nitrates; D009587:Nitrogen Isotopes; D045483:Rivers; D014874:Water Pollutants, Chemical
Environmental science and pollution research international
2,021
D009566:Nitrates; D009587:Nitrogen Isotopes; D014874:Water Pollutants, Chemical
DFT Study of Adsorption Behavior of Nitro Species on Carbon-Doped Boron Nitride Nanoribbons for Toxic Gas Sensing.
The modifications of the electronic properties on carbon-doped boron nitride nanoribbons (BNNRs) as a response to the adsorption of different nitro species were investigated in the framework of the density functional theory within the generalized gradient approximation. Calculations were performed using the SIESTA code...
10.3390/nano13081410
37,110,995
Nanomaterials (Basel, Switzerland)
2,023
Dispersion of circumferential waves in cylindrically anisotropic layered pipes in plane strain.
Dispersion spectra of circumferential waves along the periphery of circular pipes made of layered anisotropic materials do not seem to be available in literature. This note attempts to partially fill this gap by providing the dispersion spectra in two and three layered cylindrically anisotropic pipes in plane strain mo...
10.1121/1.2902180
18,537,366
D000465:Algorithms; D016880:Anisotropy; D004548:Elasticity; D008962:Models, Theoretical; D014732:Vibration
The Journal of the Acoustical Society of America
2,008
Effect of metal exchange (Os vs. Ru) and co-ligand variation (Cl(-)vs. acac(-)) on the oxidation state distribution in complexes of an o-phenylenediamido(2(-))/o-quinonediimine redox system.
The compounds OsCl2L2 (1), RuCl2L2 (2) and Ru(acac)2L (3), Ldegrees = N-phenyl-o-quinonediimine and acac- = 2,4-pentanedionato, have been synthesised and electrochemically, spectroscopically and structurally characterised with the support of detailed DFT calculations. For the new osmium compound 1, the average values f...
10.1039/b906913e
19,759,953
Dalton transactions (Cambridge, England : 2003)
2,009
Mortality study of civilian employees exposed to contaminated drinking water at USMC Base Camp Lejeune: a retrospective cohort study.
BACKGROUND Two drinking water systems at U.S. Marine Corps Base Camp Lejeune, North Carolina were contaminated with solvents during 1950s-1985. METHODS We conducted a retrospective cohort mortality study of 4,647 civilian, full-time workers employed at Camp Lejeune during 1973-1985 and potentially exposed to contamin...
10.1186/1476-069X-13-68
25,115,749
D000328:Adult; D000368:Aged; D002140:California; D060766:Drinking Water; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D058749:Military Facilities; D008889:Military Personnel; D009369:Neoplasms; D009657:North Carolina; D016273:Occupational Exposure; D010300:Parkinson Disease; D012189:Retrospective ...
Environmental health : a global access science source
2,014
D060766:Drinking Water; D014874:Water Pollutants, Chemical
Species conservation profile and revision of Salviakorolkowii (Lamiaceae, Lamiales), a narrow endemic of the Western Tian-Shan.
Background Salviakorolkowii (Lamiaceae) has been considered a species of highest conservation priority due to its narrow distribution and isolated taxonomic position. The species has been known from Uzbekistan and, questionably, Kyrgyzstan and treated as endemic to the Western Tian-Shan. Its modern conservation status ...
10.3897/BDJ.10.e89437
36,761,667
Biodiversity data journal
2,022
Adolescent offenders: comparison for sexual, violent, and property offences.
The psychological functioning and abuse history of 23 sexual, 51 violent, and 79 property adolescent offenders were compared. Minnesota Multiphasic Personality Inventory scores of these three groups did not differ although sexual offenders were twice as likely to have a history of sexual abuse, making those personal ex...
10.2466/pr0.1993.73.2.657
8,234,618
D000293:Adolescent; D002648:Child; D002649:Child Abuse; D002650:Child Abuse, Sexual; D006801:Humans; D007604:Juvenile Delinquency; D008297:Male; D011613:Psychotherapy; D012742:Sex Offenses; D013800:Theft; D014754:Violence
Psychological reports
1,993
Wideband Channel Characterization for 6G Networks in Industrial Environments.
Wireless data traffic has increased significantly due to the rapid growth of smart terminals and evolving real-time technologies. With the dramatic growth of data traffic, the existing cellular networks including Fifth-Generation (5G) networks cannot fully meet the increasingly rising data rate requirements. The Sixth-...
10.3390/s21062015
33,809,235
Sensors (Basel, Switzerland)
2,021
Optimisation of T2 and M0 measurements of bi-exponential systems.
Cramer-Rao theory and computer simulations were used to show that the errors involved in calculating the magnetization and relaxation parameters of a two-component system decrease with: (1) increasing SNR, (2) increasing number of echoes used in the fitting procedure, and (3) increasing ratio of the relaxation times of...
10.1016/j.mri.2003.05.005
14,972,396
D000818:Animals; D001847:Bone Diseases; D003198:Computer Simulation; D006736:Horses; D008279:Magnetic Resonance Imaging; D019047:Phantoms, Imaging; D012598:Sclerosis
Magnetic resonance imaging
2,004
Assessment of neural inspiratory time in ventilator-supported patients.
Neural inspiratory time (TI) is a measurement of fundamental importance in studies of patient-ventilator interaction. The measurement is usually based on recordings of flow, esophageal pressure (Pes), and transdiaphragmatic pressure (Pdi), but the concordance of such estimates of neural TI with a more direct measuremen...
10.1164/ajrccm.162.2.9901024
10,934,085
D000368:Aged; D000369:Aged, 80 and over; D004576:Electromyography; D004947:Esophagus; D006801:Humans; D008875:Middle Aged; D011175:Positive-Pressure Respiration; D011312:Pressure; D012121:Respiration, Artificial; D015656:Respiratory Mechanics; D013909:Thorax
American journal of respiratory and critical care medicine
2,000
Visualization of the Thebesian veins during coronary angiography in a 57-year-old woman.
A 57-year-old woman was hospitalized due to a type 2 respiratory failure. Electrocardiogram at admission showed inverted T waves in leads V2-V4. Coronary angiogram was performed showing no relevant stenosis. However, this exam allowed visualization of the Thebesian veins outlining the left ventricle.
10.1093/omcr/omaa053
32,760,590
Oxford medical case reports
2,020
Growth in coculture stimulates metabolism of the phenylurea herbicide isoproturon by Sphingomonas sp. strain SRS2.
Metabolism of the phenylurea herbicide isoproturon by Sphingomonas sp. strain SRS2 was significantly enhanced when the strain was grown in coculture with a soil bacterium (designated strain SRS1). Both members of this consortium were isolated from a highly enriched isoproturon-degrading culture derived from an agricult...
10.1128/AEM.68.7.3478-3485.2002
12,089,031
D006540:Herbicides; D008782:Methylurea Compounds; D008969:Molecular Sequence Data; D010671:Phenylurea Compounds; D012988:Soil Microbiology; D020578:Sphingomonas
Applied and environmental microbiology
2,002
D006540:Herbicides; D008782:Methylurea Compounds; D010671:Phenylurea Compounds; C028904:isoproturon
Registration of the number of macules in paucibacillary leprosy for evaluation of early diagnosis and individual prognosis.
The number of macules is usually registered at diagnosis in the first clinical examination of leprosy patients. The question studied here is whether this practice is of any interest as an indicator of the precocity of detection of the prognosis. The study is based on the 26,996 paucibacillary patients detected from 195...
10.5935/0305-7518.19890027
2,530,408
D006233:Disabled Persons; D006801:Humans; D015439:Leprosy, Borderline; D015441:Leprosy, Tuberculoid; D011379:Prognosis; D013997:Time Factors
Leprosy review
1,989
Sustained Suppression of Premature Ventricular Contractions by a Three-Month Pacing Adjustment.
Premature ventricular contractions (PVCs) that comprise more than 15% of total heartbeats can induce cardiomyopathy in patients with systolic dysfunction, and cardiac ablation is frequently used to reduce PVCs in this patient group. However, cardiac ablation is not entirely without hazards. We report a noninvasive meth...
10.7759/cureus.31209
36,382,325
Cureus
2,022
[Analysis of Non-serotype b Encapsulated Haemophilus influenzae Isolated from Pediatric Patients].
We analyzed non-serotype b encapsulated Haemophilus influenzae (non-b Hi) isolated from pediatric patients at Chiba Children's Hospital during 2000-2012. Among 3,532 clinical isolates of H. influenzae, there were 57 (1.6%) strains of non-b Hi, 152 (4.3%) of serotype b H. influenzae (Hib), and 3,323 (94.1%) of non-typea...
10.11150/kansenshogakuzasshi.89.237
26,552,120
D016667:Bacterial Capsules; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D006193:Haemophilus influenzae; D006801:Humans; D007223:Infant; D065288:Serogroup
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
2,015
Improved method for mutagenicity testing of gaseous compounds by using a gas sampling bag.
A simple and safety gas exposure method was developed using a gas sampling bag as an exposure vessel and a preparation vessel of diluted gas. The gas exposure conditions such as amount of S9 in the plate, volume of gas for the plate, amount of top agar, exposure period and exposure temperature were examined by mutageni...
10.1016/0027-5107(94)90307-7
7,513,814
D000818:Animals; D002070:Butadienes; D002849:Chromatography, Gas; D005740:Gases; D008110:Liver Extracts; D008297:Male; D009152:Mutagenicity Tests; D009153:Mutagens; D051381:Rats; D017207:Rats, Sprague-Dawley; D012486:Salmonella typhimurium; D013696:Temperature
Mutation research
1,994
D002070:Butadienes; D005740:Gases; D008110:Liver Extracts; D009153:Mutagens; C031763:1,3-butadiene
Histidine decarboxylase is identified as a potential biomarker of intestinal mucosal injury in patients with acute intestinal obstruction.
Various biomarkers currently used for the diagnosis of intestinal mucosal injury (IMI) in patients with acute intestinal obstruction have low sensitivity and specificity. In the present study, IMI, as indicated by the impaired expression of tight junction proteins, including zonula occludens-1, occludin and claudin-1, ...
10.2119/molmed.2011.00107
21,915,437
D000208:Acute Disease; D000328:Adult; D000368:Aged; D015415:Biomarkers; D015153:Blotting, Western; D016022:Case-Control Studies; D062445:Claudin-1; D005260:Female; D005456:Fluorescent Dyes; D006640:Histidine Decarboxylase; D006801:Humans; D007150:Immunohistochemistry; D007413:Intestinal Mucosa; D007415:Intestinal Obstr...
Molecular medicine (Cambridge, Mass.)
2,011
D015415:Biomarkers; C568108:CLDN1 protein, human; D062445:Claudin-1; D005456:Fluorescent Dyes; D008565:Membrane Proteins; C568985:OCLN protein, human; D062793:Occludin; D010750:Phosphoproteins; C569042:TJP1 protein, human; D062826:Zonula Occludens-1 Protein; D006640:Histidine Decarboxylase
[Choice and technical problems of digestive tract reconstruction in laparoscopic gastrointestinal surgery].
Gastrointestinal tract reconstruction is a key procedure in laparoscopic surgery for gastrointestinal diseases. The reconstruction procedure in laparoscopic surgery is not superior to conventional surgery. Reconstruction procedures such as Billroth I, Billroth II( and Roux-en-Y anastomosis are widely used in laparoscop...
21,713,696
D000714:Anastomosis, Surgical; D013505:Digestive System Surgical Procedures; D006801:Humans; D010535:Laparoscopy
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
2,011
Sleep disorders and systemic lupus erythematosus.
OBJECTIVE Sleep disturbances are often seen in rheumatic diseases, including systemic lupus erythematosus (SLE). However, the prevalence of sleep disorders in SLE as well as the contributing factors to their occurrence remain poorly understood. The aim of this paper is to review the clinical and psychobiological data o...
10.1177/0961203313518623
24,421,291
D003863:Depression; D005221:Fatigue; D006801:Humans; D008180:Lupus Erythematosus, Systemic; D008954:Models, Biological; D008960:Models, Psychological; D010146:Pain; D015995:Prevalence; D012893:Sleep Wake Disorders
Lupus
2,014
The 2009-2010 H1N1 vaccination campaign for patients with egg allergy in a region of France.
We describe our experience of the influenza H1N1 vaccination in patients with egg allergy. All patients tolerated the vaccination in a simple or double dose protocol without any significant allergic reaction in this series.
10.1111/j.1398-9995.2010.02461.x
20,716,317
D021181:Egg Hypersensitivity; D005602:France; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007252:Influenza Vaccines; D009313:National Health Programs; D014611:Vaccination
Allergy
2,011
D007252:Influenza Vaccines
Eyes Matched to the Prize: The State of Matched Filters in Insect Visual Circuits.
Confronted with an ever-changing visual landscape, animals must be able to detect relevant stimuli and translate this information into behavioral output. A visual scene contains an abundance of information: to interpret the entirety of it would be uneconomical. To optimally perform this task, neural mechanisms exist to...
10.3389/fncir.2018.00026
29,670,512
D000818:Animals; D001522:Behavior, Animal; D007313:Insecta; D014795:Visual Pathways; D014796:Visual Perception
Frontiers in neural circuits
2,018
Polaronic behavior of undoped high-T(c) cuprate superconductors from angle-resolved photoemission spectra.
We present angle-resolved photoemission spectroscopy (ARPES) data on undoped La2CuO4, indicating polaronic coupling between bosons and charge carriers. Using a shell model, we calculate the electron-phonon coupling and find that it is strong enough to give self-trapped polarons. We develop an efficient method for calcu...
10.1103/PhysRevLett.95.227002
16,384,255
Physical review letters
2,005
Outbreak investigation, molecular detection, and characterization of foot and mouth disease virus in the Southern part of Bangladesh.
OBJECTIVE The objective of the study was to investigate Foot and Mouth Disease virus (FMDV) outbreak in cattle in the Sarankhola Upazila under Bagerhat district of Bangladesh with isolation, identification, and molecular characterization of FMDV during April 2018. MATERIALS AND METHODS This Upazila is located at sout...
10.5455/javar.2019.f353
31,583,231
Journal of advanced veterinary and animal research
2,019
Chromosome studies of patients on long-term lithium therapy for psychiatric disorders.
Chromosome studies, including sister chromatid exchange techniques, were performed on blood samples from 23 patients receiving long-term, continuous lithium therapy for psychiatric disorders. Nineteen healthy, age-matched individuals were used as controls. No increase in chromosome damage was detected, when samples fro...
6,792,477
D000328:Adult; D002877:Chromosomes, Human; D005260:Female; D006801:Humans; D008094:Lithium; D008134:Long-Term Care; D008297:Male; D001523:Mental Disorders; D008875:Middle Aged; D012854:Sister Chromatid Exchange
The Medical journal of Australia
1,981
D008094:Lithium
Conduction velocity and fibre diameter of the peroneal nerve in normal and growth retarded fetal sheep.
In this study we have examined structural and functional aspects of nerve fibre development in experimentally growth retarded fetal sheep following restriction of placental growth by carunclectomy in 5 ewes. Measurement of whole-nerve conduction velocity in the peroneal nerve showed, for the most rapidly conducting fib...
10.1016/0304-3940(89)90282-6
2,748,006
D000818:Animals; D005260:Female; D005317:Fetal Growth Retardation; D005865:Gestational Age; D009413:Nerve Fibers, Myelinated; D009431:Neural Conduction; D010543:Peroneal Nerve; D011247:Pregnancy; D012756:Sheep
Neuroscience letters
1,989
A recombinant Fab fragment-based electrochemical immunosensor for the determination of testosterone in bovine urine.
This work describes the development of an electrochemical, recombinant Fab fragment-based immunosensor for the detection of testosterone in bovine urine. The sensor comprised of a testosterone conjugate on the surface of screen-printed electrodes, and recognition followed by an anti-testosterone Fab fragment. The use o...
10.1016/j.bios.2006.08.002
16,962,310
D000818:Animals; D015374:Biosensing Techniques; D002417:Cattle; D003429:Cross Reactions; D004563:Electrochemistry; D004566:Electrodes; D004797:Enzyme-Linked Immunosorbent Assay; D008401:Gas Chromatography-Mass Spectrometry; D007140:Immunoglobulin Fab Fragments; D008297:Male; D011994:Recombinant Proteins; D013739:Testos...
Biosensors & bioelectronics
2,007
D007140:Immunoglobulin Fab Fragments; D011994:Recombinant Proteins; D013739:Testosterone
The reverse question mark and L.G. Kempe incisions for decompressive craniectomy: A case series and narrative review of the literature.
Background Decompressive craniectomy (DC) is a lifesaving procedure, relieving intracranial hypertension. Conventionally, DCs are performed by a reverse question mark (RQM) incision. However, the use of the L. G. Kempe's (LGK) incision has increased in the last decade. We aim to describe the surgical nuances of the LGK...
10.25259/SNI_59_2022
35,855,131
Surgical neurology international
2,022