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Enrichment of target sequences for next-generation sequencing applications in research and diagnostics. | Abstract Targeted re-sequencing such as gene panel sequencing (GPS) has become very popular in medical genetics, both for research projects and in diagnostic settings. The technical principles of the different enrichment methods have been reviewed several times before; however, new enrichment products are constantly en... | 24,013,102 | D001483:Base Sequence; D035843:Biomedical Research; D006801:Humans; D057089:Pathology, Molecular; D017422:Sequence Analysis, DNA | Biological chemistry | 2,014 | ||
The use of epidemiologic methods in family practice. | Epidemiologic methods of research can be readily used in family practice. Since the 19th century, family physicians have used epidemiologic methods in making important contributions to the understanding of disease. Using these methods requires an organized practice including patient registers, encounter data, and detai... | 347,021 | D004812:Epidemiologic Methods; D005194:Family Practice; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D012106:Research; D012107:Research Design | The Journal of family practice | 1,978 | ||
Body surface area prediction in normal, hypermuscular, and obese mice. | BACKGROUND
Accurate determination of body surface area (BSA) in experimental animals is essential for modeling effects of burn injury or drug metabolism. Two-dimensional surface area is related to three-dimensional body volume, which in turn can be estimated from body mass. The Meeh equation relates body surface area t... | 10.1016/j.jss.2008.05.002 | 18,952,236 | D000465:Algorithms; D000818:Animals; D001823:Body Composition; D001830:Body Surface Area; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D023421:Models, Animal; D009132:Muscles; D009765:Obesity; D010641:Phenotype | The Journal of surgical research | 2,009 | |
Mechanical factors affecting protein turnover in isolated rat hearts. | Induction of cardiac work increased protein synthesis in hearts supplied glucose or a mixture simulating normal plasma levels of glucose, insulin, glucagon, lactate, and beta-hydroxybutyrate. During 2 h of perfusion, cardiac work did not accelerate protein synthesis in hearts supplied a mixture of glucose, lactate, and... | 3,758,375 | D000818:Animals; D001794:Blood Pressure; D006321:Heart; D066298:In Vitro Techniques; D009200:Myocardial Contraction; D009206:Myocardium; D010477:Perfusion; D014176:Protein Biosynthesis; D011506:Proteins; D051381:Rats | Federation proceedings | 1,986 | D011506:Proteins | |
Identification of novel BRCA founder mutations in Middle Eastern breast cancer patients using capture and Sanger sequencing analysis. | Ethnic differences of breast cancer genomics have prompted us to investigate the spectra of BRCA1 and BRCA2 mutations in different populations. The prevalence and effect of BRCA 1 and BRCA 2 mutations in Middle Eastern population is not fully explored. To characterize the prevalence of BRCA mutations in Middle Eastern ... | 10.1002/ijc.30143 | 27,082,205 | D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D019313:BRCA1 Protein; D024682:BRCA2 Protein; D001943:Breast Neoplasms; D004252:DNA Mutational Analysis; D005091:Exons; D005260:Female; D018703:Founder Effect; D020022:Genetic Predisposition to Disease; D005838:Genotype; D018095:Germ-Line Mutation; D006239:Haplo... | International journal of cancer | 2,016 | D019313:BRCA1 Protein; D024682:BRCA2 Protein |
The 5th Annual One Mind Summit: Lessons Learned About "Science Informing Brain Health Policies and Practice". | Advances in science frequently precede changes in clinical care by several years or even decades. To better understand the path to translation, we invited experts to share their perspectives at the 5th Annual One Mind Summit: "Science Informing Brain Health Policies and Practice," which was held on May 24-25, 2016, in ... | 10.1089/neu.2016.4821 | 28,351,324 | Journal of neurotrauma | 2,017 | ||
Influence of apical Na+ entry on Na(+)-K(+)-ATPase in amphibian distal nephron cells in culture. | 1. Transepithelial Na+ transport, Na(+)-K(+)-ATPase activity and ouabain binding were measured in cells originating from the distal part of amphibian nephron (A6) which form 'tight' monolayers in culture, under standard (control) incubation conditions and after various manoeuvres designed to reversibly interfere with N... | 10.1113/jphysiol.1992.sp019359 | 1,338,106 | D000818:Animals; D001693:Biological Transport, Active; D002478:Cells, Cultured; D008564:Membrane Potentials; D009399:Nephrons; D010042:Ouabain; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D013997:Time Factors; D014982:Xenopus laevis | The Journal of physiology | 1,992 | D010042:Ouabain; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase |
[The effect of disorders of thrombocyte functional activity on the microcirculatory status in the lungs and on external respiratory function in patients with aspirin-induced asthma]. | Platelet aggregation, pulmonary microcirculation and external respiration were studied against clinical appearance of the disease in 20 patients with aspirin-sensitive asthma (ASA) and 10 asthmatics without aspirin intolerance. All ASA patients were found to exhibit higher intensity and rate of platelet aggregation ind... | 8,059,372 | D000328:Adult; D001241:Aspirin; D001249:Asthma; D001792:Blood Platelets; D002196:Capillaries; D003289:Convalescence; D006801:Humans; D008168:Lung; D008297:Male; D010974:Platelet Aggregation; D012119:Respiration | Terapevticheskii arkhiv | 1,993 | D001241:Aspirin | |
A QSPR study of the p solute polarity parameter to estimate retention in HPLC. | A Quantitative Structure-Property Relationship (QSPR) model is developed to calculate the solute polarity parameter p of a set of 233 compounds of a very different chemical nature. The proposed model, derived from multiple linear regression, contains four descriptors calculated from the molecular structure and the well... | 10.1021/ci0340660 | 12,870,917 | Journal of chemical information and computer sciences | 2,003 | ||
Metal vs bioabsorbable interference screws: initial fixation. | Interference screws are used for graft fixation in anterior cruciate ligament reconstruction. There is current debate as to whether metal or bioabsorbable varieties provide the optimal results. This paper provides a critique of the single load-to-failure uniaxial tensile test data available in the literature, which pro... | 10.1243/095441103762597746 | 12,578,220 | D020341:Absorbable Implants; D000818:Animals; D016118:Anterior Cruciate Ligament; D000070598:Anterior Cruciate Ligament Injuries; D001863:Bone Screws; D002417:Cattle; D019544:Equipment Failure Analysis; D006801:Humans; D016268:Internal Fixators; D007719:Knee Joint; D008670:Metals; D011475:Prosthesis Failure; D012756:Sh... | Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine | 2,003 | D008670:Metals |
Cardiac fusion imaging with low-dose computed tomography using prospective electrocardiogram gating. | In a 66-year-old patient with prolonged episodes of chest pain, catheter angiography revealed total occlusions of the right coronary artery and the distal circumflex artery (CX) as well as 2 sequential significant stenoses in the proximal CX and one significant stenosis in the proximal left anterior descending artery (... | 10.1097/RLU.0b013e318177933c | 18,580,239 | D000368:Aged; D003251:Constriction, Pathologic; D017023:Coronary Angiography; D003952:Diagnostic Imaging; D004562:Electrocardiography; D005260:Female; D019788:Fluorodeoxyglucose F18; D006321:Heart; D006801:Humans; D009206:Myocardium; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray ... | Clinical nuclear medicine | 2,008 | D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18 |
Assessment of biofilm cell removal and killing and biocide efficacy using the microtiter plate test. | Biofilm formation on surfaces has serious economic and environmental implications. Growth of biofilm within a water distribution system can lead to problems such as biocorrosion and biofouling accumulation. To prevent and control these occurrences, it is necessary to use suitable biocides to remove the biofilm and kill... | 10.1080/08927010701190011 | 17,453,732 | D000150:Acinetobacter; D001422:Bacterial Adhesion; D001431:Bacteriological Techniques; D018441:Biofilms; D003300:Copper; D004202:Disinfectants; D008855:Microscopy, Electron, Scanning; D013499:Surface Properties; D014871:Water Microbiology; D015032:Zinc | Biofouling | 2,007 | D004202:Disinfectants; C048399:brass; D003300:Copper; D015032:Zinc |
AC099850.3/NCAPG Axis Predicts Poor Prognosis and is Associated with Resistance to EGFR Tyrosine-Kinase Inhibitors in Lung Adenocarcinoma. | Background
TKI-acquired resistance markedly interferes with treatment of lung cancer patients with EGFR mutant features. Long non-coding RNAs (lncRNAs) modify EGFR-TKI resistance during tumor progression. Non-structural maintenance of chromosomes condensin I complex subunit G (NCAPG) is a mitosis-related protein that i... | 10.2147/IJGM.S365695 | 36,061,963 | International journal of general medicine | 2,022 | ||
Flexural behaviour of strengthened damaged steel beams using carbon fibre-reinforced polymer sheets. | This paper presents the test and finite element analysis results of a study on the flexural behaviour of damaged steel beams strengthened with carbon fibre-reinforced polymer (CFRP) sheets. The test results showed that the yield load, ultimate load and elastic stiffness of the steel beams with 100% loss of tension flan... | 10.1038/s41598-022-14471-9 | 35,710,935 | Scientific reports | 2,022 | ||
Outcomes of second opinions in general internal medicine. | BACKGROUND
To date, the outcomes of second opinions in internal medicine in terms of diagnostic yield and patient benefit have not been studied extensively. This retrospective study explores the outcomes of second opinions at a general internal medicine outpatient clinic in an academic hospital.
METHODS
A register of... | 10.1371/journal.pone.0236048 | 32,645,107 | D000328:Adult; D001774:Blood Chemical Analysis; D005260:Female; D005500:Follow-Up Studies; D058006:General Practice; D006801:Humans; D007388:Internal Medicine; D008297:Male; D008829:Microbiology; D012017:Referral and Consultation; D016482:Urinalysis | PloS one | 2,020 | |
Potentially inappropriate medications in Chinese older adults: The beers criteria compared with the screening tool of older persons' prescriptions criteria. | AIM
The present study aimed to assess the prevalence of potentially inappropriate medications (PIM) use in West China Hospital residents aged ≥65 years, using two sets of criteria - the Beers and Screening Tool of Older Persons' Prescriptions (STOPP) criteria - and to compare the Beers and STOPP criteria, and to determ... | 10.1111/ggi.12999 | 28,224,703 | D000368:Aged; D000369:Aged, 80 and over; D002681:China; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D057970:Inappropriate Prescribing; D008297:Male; D008403:Mass Screening; D000067561:Potentially Inappropriate Medication List; D015203:Reproducibility of Results; D012189:Retrospective Studies | Geriatrics & gerontology international | 2,017 | |
Adsorption thermodynamics of acidic proline-rich human salivary proteins onto calcium apatites. | The thermodynamics of adsorption of four acidic proline-rich salivary proteins from their aqueous solutions onto hydroxyapatite (HA) and fluorapatite (FA) have been analyzed. Enthalpies and entropies of adsorption were derived from isotherms at 37 degrees C and 4 degrees C and led to the unexpected conclusion that adso... | 7,061,460 | D000327:Adsorption; D002118:Calcium; D006801:Humans; D006882:Hydroxyapatites; D008433:Mathematics; D008970:Molecular Weight; D011392:Proline; D012471:Salivary Proteins and Peptides; D013816:Thermodynamics | The Journal of biological chemistry | 1,982 | D006882:Hydroxyapatites; D012471:Salivary Proteins and Peptides; D011392:Proline; D002118:Calcium | |
MBL2 polymorphisms screening in a regional Italian CF Center. | We performed MBL2 genotyping in 47 CF patients-cared of at the regional CF Centre of Trieste-trying to establish a correlation within allelic variants of MBL2 and modification of patients' clinical outcome. FEV1 values were significantly lowered and a significantly earlier age at onset of Pseudomonas aeruginosa colonis... | 10.1016/j.jcf.2005.04.001 | 16,046,196 | D000328:Adult; D003550:Cystic Fibrosis; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D018450:Disease Progression; D004198:Disease Susceptibility; D005260:Female; D005541:Forced Expiratory Volume; D005787:Gene Frequency; D005819:Genetic Markers; D005820:Genetic Testing; D005838:Genotype; D006801:Humans; ... | Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society | 2,005 | C505032:CFTR protein, human; D005819:Genetic Markers; C445619:MBL2 protein, human; D037601:Mannose-Binding Lectin; D019005:Cystic Fibrosis Transmembrane Conductance Regulator |
Autophagy regulatory molecule, TMEM74, interacts with BIK and inhibits BIK-induced apoptosis. | TMEM74 (Transmembrane protein 74), a lysosome transmembrane protein, induces cell autophagy. Knockdown of TMEM74 abolished EBSS-induced autophagy. BIK, belonging to BOP (BH3-only protein) protein family, has been reported to induce cell apoptosis. Autophagy and apoptosis, as different pathways regulated by extra- or in... | 10.1016/j.cellsig.2017.04.005 | 28,412,412 | D017209:Apoptosis; D051017:Apoptosis Regulatory Proteins; D001343:Autophagy; D055785:Gene Knockdown Techniques; D006367:HeLa Cells; D006801:Humans; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D011485:Protein Binding; D000072417:Protein Domains | Cellular signalling | 2,017 | D051017:Apoptosis Regulatory Proteins; C096820:BIK protein, human; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; C528238:TMEM74 protein, human |
The influence of glucagon on the hepatic transport of taurocholate in isolated perfused rat liver: kinetic analysis by the multiple indicator dilution technique. | Glucagon has been demonstrated to stimulate the uptake of bile acid in isolated rat hepatocytes (Am. J. Physiol., 249, G427 (1985)). In the present study, we determined the influence of glucagon on the hepatic transport of a bile acid, taurocholate (TCA), in isolated rat livers. A single-pass perfusion and a rapid-inje... | 10.1248/bpb.16.791 | 8,220,327 | D000818:Animals; D001646:Bile; D002417:Cattle; D005934:Glucagon; D066298:In Vitro Techniques; D007201:Indicator Dilution Techniques; D007700:Kinetics; D008099:Liver; D010477:Perfusion; D051381:Rats; D013656:Taurocholic Acid | Biological & pharmaceutical bulletin | 1,993 | D013656:Taurocholic Acid; D005934:Glucagon |
Cadherins and catenins in clival chordomas: correlation of expression with tumor aggressiveness. | The local invasiveness and occasional rapid growth of chordomas, despite optimal treatment, highlight the need to develop ways to predict their biologic behavior. Alterations in adhesion proteins have been shown to participate in proliferation, invasiveness, and metastasis in epithelial tumors. We therefore analyzed th... | 10.1097/01.pas.0000180447.25141.a4 | 16,224,208 | D000293:Adolescent; D000328:Adult; D000368:Aged; D015820:Cadherins; D051177:Catenins; D002817:Chordoma; D003388:Cranial Fossa, Posterior; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D019292:Skull Base Neoplasms | The American journal of surgical pathology | 2,005 | D015820:Cadherins; D051177:Catenins |
Optimization on Adsorption Process of Congo Red onto Magnetic Ni0.5Cu0.5Fe₂O₄/SiO₂ Nanocomposites and Their Adsorption Mechanism. | Magnetic Ni0.5Cu0.5Fe₂O₄/SiO₂ nanocomposites were prepared via a solution combustion process, and were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM), Energy dispersive X-ray Spectroscopy (EDX) and vibrating sample magnetometer (VSM). The magnetic... | 10.1166/jnn.2020.16916 | 31,383,074 | Journal of nanoscience and nanotechnology | 2,020 | ||
The influence of vasopressin on hypothalamic corticotrophin releasing activity in rats with inherited diabetes insipidus. | 1. The corticotrophin releasing activity of hypothalamic extracts from rats congenitally lacking vasopressin (Brattleboro strain) has been studied in the presence and absence of arginine vasopressin and its antiserum. 2. Hypothalamic extracts from Brattleboro rats stimulated the production of corticotrophin by pituitar... | 10.1113/jphysiol.1981.sp013612 | 6,973,627 | D000818:Animals; D001127:Arginine Vasopressin; D003346:Corticotropin-Releasing Hormone; D003919:Diabetes Insipidus; D007031:Hypothalamus; D007106:Immune Sera; D066298:In Vitro Techniques; D008297:Male; D051381:Rats; D012636:Secretory Rate | The Journal of physiology | 1,981 | D007106:Immune Sera; D001127:Arginine Vasopressin; D003346:Corticotropin-Releasing Hormone |
A global perspective: technology in home care. Discussion. | Technological advances are changing the way the world shares information and conducts daily business, CARING asked home care colleagues around the world to respond to a question about technology's role in home care delivery. Although the degree of technology's involvement differs from country to country, each country i... | 10,169,878 | D003195:Computer Communication Networks; D014943:Global Health; D006699:Home Care Services; D006801:Humans; D007391:International Cooperation; D019035:Rural Health Services; D018581:Technology Transfer | Caring : National Association for Home Care magazine | 1,997 | ||
Stamey-Martius procedure for severe genuine stress incontinence. | There are few options now available to treat patients with severe genuine stress incontinence caused by urethral failure. These patients usually have a low maximum urethral closure pressure (less than 20 cm of water) and anterior vaginal wall scarring caused by previous surgery. In 32 such patients we used the Martius ... | 10.1111/j.1464-410x.1992.tb15454.x | 1,737,250 | D000273:Adipose Tissue; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications; D012008:Recurrence; D012086:Reoperation; D013514:Surgical Procedures, Operative; D014550:Urinary Incontinence, Stress; D014563:Uro... | British journal of urology | 1,992 | |
Finding Colour in Conformity Part II-Reflections on Structured Professional Judgement and Cross-Cultural Risk Assessment. | There has been an increasing interest in cross-cultural risk assessment over the past 5 years. Much of this has been driven by concerns that particular risk instruments may be biased against, or ill-suited to, non-White offending populations. A growing body of work has asserted that unique cultural-specific risk factor... | 10.1177/0306624X20928025 | 32,524,914 | D003116:Color; D003431:Cross-Cultural Comparison; D006801:Humans; D044382:Population Groups; D018570:Risk Assessment; D012307:Risk Factors | International journal of offender therapy and comparative criminology | 2,021 | |
Antibiotic treatment and post-handling survival of reindeer calves in Alaska. | Free ranging reindeer (Rangifer tarandus tarandus) are driven into corral systems and handled each summer on the Seward Peninsula (Alaska, USA). During June and July of 1995-96 reindeer calves were inspected for injury, handled, weighed, and randomly treated with long-acting oxytetracycline. Calves that returned to sub... | 10.7589/0090-3558-35.4.735 | 10,574,533 | D000413:Alaska; D000818:Animals; D000900:Anti-Bacterial Agents; D019072:Antibiotic Prophylaxis; D001424:Bacterial Infections; D001835:Body Weight; D005260:Female; D006234:Handling, Psychological; D007273:Injections, Intramuscular; D016014:Linear Models; D008297:Male; D010118:Oxytetracycline; D011897:Random Allocation; ... | Journal of wildlife diseases | 1,999 | D000900:Anti-Bacterial Agents; D010118:Oxytetracycline |
Epidemiology survey of rhegmatogenous retinal detachment in Beixinjing District, Shanghai, China. | PURPOSE
To investigate the recent incidence and related risk factors of rhegmatogenous retinal detachment (RRD) in Chinese people.
METHODS
This study was an incidence survey based on data for 108,132 persons in Beixinjing District, Shanghai, China. Patients with RRD were inpatients, outpatients, and patients from the... | 10.1097/00006982-200206000-00007 | 12,055,462 | D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment; D012307:Risk Factors; D017678:Sex D... | Retina (Philadelphia, Pa.) | 2,002 | |
Coronary artery calcification outperforms thoracic aortic calcification for the prediction of myocardial infarction and all-cause mortality: the Heinz Nixdorf Recall Study. | BACKGROUND
Thoracic aortic calcification (TAC) is associated with cardiovascular (CV) risk factors and prevalent coronary artery disease. We aimed to investigate whether TAC burden is associated with incident myocardial infarction (MI) and all-cause mortality in subjects without known coronary artery disease and to det... | 10.1177/2047487313482281 | 23,467,675 | D000368:Aged; D001013:Aorta, Thoracic; D001018:Aortic Diseases; D002114:Calcinosis; D002423:Cause of Death; D003324:Coronary Artery Disease; D005500:Follow-Up Studies; D005858:Germany; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D012189:Retrospective Studies; D01... | European journal of preventive cardiology | 2,014 | |
Simulation of clipping position for cerebral aneurysms using three-dimensional computed tomography angiography. | A novel method for the simulation of the clipping position for cerebral aneurysms based on three-dimensional computed tomography (3D CT) angiography was evaluated. Rotating the regional 3D CT angiography images including the aneurysm provided the virtual intraoperative views of 36 cerebral aneurysms that were eligible ... | 10.2176/nmc.44.6 | 14,959,930 | D000368:Aged; D017542:Aneurysm, Ruptured; D002533:Cerebral Angiography; D003198:Computer Simulation; D004724:Endoscopy; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D002532:Intracranial Aneurysm; D008875:Middle Aged; D011183:Postoperative Complications... | Neurologia medico-chirurgica | 2,004 | |
Paracrine signaling of human mesenchymal stem cell modulates retinal microglia population number and phenotype in vitro. | PURPOSE
Cellular therapy with mesenchymal stem cells (MSC) is emerging as an effective option to treat optic neuropathies. In models of retinal degeneration, MSC injected in the vitreous body protects injured retinal ganglion cells and stimulate their regeneration, however the mechanism is still unknown. Considering th... | 10.1016/j.exer.2020.108212 | 32,910,940 | D000818:Animals; D002470:Cell Survival; D064987:Cell- and Tissue-Based Therapy; D018920:Coculture Techniques; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D059630:Mesenchymal Stem Cells; D017628:Microglia; D009416:Nerve Regeneration; D019899:Paracrine Communication; D010641:Phenotype; D051381:Rats; D01... | Experimental eye research | 2,020 | |
[Histological findings of the mucosa of the larynx in healthy individuals]. | A histological study of the laryngeal mucosa was carried out in one hundred biopsy specimens taken out, within the first 24 hours after death, from individuals who didn't die because of laryngeal disease. The histological findings were correlated with regard to the age, sex and habits of these individuals and led to th... | 6,834,942 | D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D004825:Epiglottis; D004848:Epithelium; D005260:Female; D006801:Humans; D007223:Infant; D007820:Laryngeal Mucosa; D007830:Larynx; D008297:Male; D008875:Middle Aged; D014827:Vocal Cords | Laryngologie, Rhinologie, Otologie | 1,983 | ||
[Dynamics of visual hand localization in the 24-hour observation of persons working under conditions of additional loads]. | Examined--by means of a Starkiewicz's hand localizer--were 170 right-hand workers of a paper factory working in conditions of excessive noise and high temperature of the surroundings. Analyzed were 140 persons tested 4 times in the period of each production shift (6.00-14.00; 14.00-22.00, and 22.00-6.00). The analysis ... | 2,593,595 | D002940:Circadian Rhythm; D005556:Form Perception; D006225:Hand; D006358:Hot Temperature; D006801:Humans; D009623:Noise, Occupational; D009787:Occupational Medicine; D010209:Paper; D010364:Pattern Recognition, Visual; D011044:Poland; D013028:Space Perception; D013997:Time Factors | Klinika oczna | 1,989 | ||
Effects of housing relocation on immunocompetence and psychosocial functioning in older adults. | BACKGROUND
The psychological and physical response to moderate life stressors among older adults has not been well characterized. This research examines effects of voluntary housing relocation on distress and immune function in healthy older adults as a model for studying the effects of moderate life stress.
METHODS
... | 10.1093/gerona/56.2.m97 | 11,213,283 | D000223:Adaptation, Psychological; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D005260:Female; D006798:Housing; D006801:Humans; D007121:Immunocompetence; D007398:Interpersonal Relations; D007694:Killer Cells, Natural; D008297:Male; D013312:Stress, Physiological | The journals of gerontology. Series A, Biological sciences and medical sciences | 2,001 | |
Synthesis and antibacterial evaluation of novel 2-[N-Imidoylpyrrolidinyl] carbapenems. | The synthesis, antibacterial activity and DHP-susceptibility of a series of novel carbapenems, directly linked with heterocyclic moiety are described. Especially, the compounds linked pyrrolidine-carbapenem exhibited to have a good antibacterial activity against Staphylococcus aureus (MRSA) as well as Pseudomonas aerug... | 10.1016/s0960-894x(01)00753-3 | 11,814,802 | D000818:Animals; D000900:Anti-Bacterial Agents; D015780:Carbapenems; D004150:Dipeptidases; D006801:Humans; D007668:Kidney; D051379:Mice; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa; D013211:Staphylococcus aureus; D013329:Structure-Activity Relationship; D013552:Swine | Bioorganic & medicinal chemistry letters | 2,002 | D000900:Anti-Bacterial Agents; D015780:Carbapenems; D004150:Dipeptidases; C038937:dipeptidase |
[Identification of proliferating cells in Taenia solium cysts]. | Neoblasts are totipotent cells, solely responsible for the proliferation and maturation of tissues in free-living flatworms. Similar cells have been isolated from parasitic flatworms such as Echinococcus. Taenia solium causes human taeniasis (intestinal) and cysticercosis in humans and pigs. Brain infection with larvae... | 25,597,721 | D000818:Animals; D049109:Cell Proliferation; D003552:Cysticercus; D041201:Taenia solium | Revista peruana de medicina experimental y salud publica | 2,014 | ||
Calcium modulates the lipid dynamics of rat hepatocyte plasma membranes by direct and indirect mechanisms. | Calcium ion decreases the motional freedom of lipid molecules in isolated rat hepatocyte plasma membranes and in sonicated dispersions (liposomes) of the membrane lipid. The decrease in lipid fluidity was monitored by estimation of the fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene. At least two processes a... | 10.1021/bi00562a017 | 6,775,694 | D000818:Animals; D002118:Calcium; D002413:Cations, Divalent; D002462:Cell Membrane; D004492:Edetic Acid; D066298:In Vitro Techniques; D008081:Liposomes; D008099:Liver; D008297:Male; D008560:Membrane Fluidity; D008563:Membrane Lipids; D051381:Rats | Biochemistry | 1,980 | D002413:Cations, Divalent; D008081:Liposomes; D008563:Membrane Lipids; D004492:Edetic Acid; D002118:Calcium |
[Awareness training for domestic violence for medical professionals. Are they efficient too?] | BACKGROUND
According to studies conducted by the European Union, 33% of all women over the age of 15 are affected by domestic violence and tend to turn to the health care system to seek help. The experience of violence has serious consequences not only for the psychological, but also for the physical health of those af... | 10.1007/s40211-020-00338-w | 32,112,262 | D017579:Domestic Violence; D005260:Female; D006282:Health Personnel; D006801:Humans; D011795:Surveys and Questionnaires | Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater | 2,020 | |
How Modifications of Corneal Cross-Linking Protocols Influence Corneal Resistance to Enzymatic Digestion and Treatment Depth. | Purpose
The purpose of this study was to determine the effects of the Photoactivated Chromophore for Keratitis Corneal Cross-Linking (PACK-CXL) protocol modifications on corneal resistance to enzymatic digestion and treatment depth.
Methods
Eight hundred one ex vivo porcine eyes were randomly divided into groups of 1... | 10.1167/tvst.12.5.18 | 37,191,620 | D013552:Swine; D000818:Animals; D017319:Photosensitizing Agents; D000094504:Corneal Cross-Linking; D003315:Cornea; D012256:Riboflavin; D007634:Keratitis; D004063:Digestion; D003432:Cross-Linking Reagents | Translational vision science & technology | 2,023 | D017319:Photosensitizing Agents; D012256:Riboflavin; D003432:Cross-Linking Reagents |
A randomized trial of improved weight loss with a prepared meal plan in overweight and obese patients: impact on cardiovascular risk reduction. | OBJECTIVE
To assess the long-term effects of a prepackaged, nutritionally complete, prepared meal plan compared with a usual-care diet (UCD) on weight loss and cardiovascular risk factors in overweight and obese persons.
DESIGN
In this randomized multicenter study, 302 persons with hypertension and dyslipidemia (n = ... | 10.1001/archinte.160.14.2150 | 10,904,458 | D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases; D004032:Diet; D005260:Female; D005518:Food Preferences; D005527:Food, Fortified; D006439:Hemodynamics; D006801:Humans; D008055:Lipids; D008297:Male; D008875:Middle Aged; D009753:Nutritive Value; D009765:Obesity; D010349:Patient Compliance; D011788:Quality of... | Archives of internal medicine | 2,000 | D008055:Lipids |
Biological citizenship: the science and politics of Chernobyl-exposed populations. | In the transition out of socialism to market capitalism, bodies, populations, and categories of citizenship have been reordered. The rational-technical management of group affected by the Chernobyl disaster in Ukraine is a window into this contested process. Chernobyl exemplifies a moment when scientific knowability co... | 10.1086/649405 | 15,484,388 | D001690:Biological Science Disciplines; D004190:Disasters; D049673:History, 20th Century; D049674:History, 21st Century; D009678:Nuclear Energy; D011057:Politics; D011634:Public Health; D011635:Public Health Administration; D014586:USSR; D014455:Ukraine | Osiris | 2,004 | |
Plain-Body Octopus's (Callistoctopus aspilosomatis) Learning about Objects via Both Visual and Tactile Sensory Inputs: A Pilot Study. | Although various recognizing abilities have been revealed for octopuses, they predominantly deal with only a few species. Therefore, cognition diversity among other octopus species that have been overlooked needs to be investigated. We investigated whether plain-body octopus can learn a symbolic stimulus, for the reaso... | 10.2108/zs210034 | 34,664,913 | D000818:Animals; D003216:Conditioning, Operant; D007858:Learning; D049831:Octopodiformes; D010865:Pilot Projects; D014110:Touch; D014796:Visual Perception | Zoological science | 2,021 | |
Star-shaped trinuclear cyclometalated platinum(II) complexes as single-component emitters in white-emitting PLEDs. | Two star-shaped phosphorescent small molecules, Ph-3FPt(pic) and 4Ph-3FPt(pic), are single-component emitters in polymer white-light-emitting diodes (WPLEDs) that are comprised of three blue-light-emitting phosphorescent chromophores of FPt(pic) and are attached to benzene-1,3,5-trioxy- and 1,3,5-tri(4-oxyphenyl)benzen... | 10.1002/asia.201200182 | 22,718,560 | Chemistry, an Asian journal | 2,012 | ||
Non-stomatal processes reduce gross primary productivity in temperate forest ecosystems during severe edaphic drought. | Severe drought events are known to cause important reductions of gross primary productivity (GPP) in forest ecosystems. However, it is still unclear whether this reduction originates from stomatal closure (Stomatal Origin Limitation) and/or non-stomatal limitations (Non-SOL). In this study, we investigated the impact o... | 10.1098/rstb.2019.0527 | 32,892,725 | D001272:Atmosphere; D057231:Climate Change; D055864:Droughts; D005060:Europe; D065928:Forests; D054046:Plant Stomata; D014197:Trees | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 2,020 | |
Signal transduction during in vitro lymphocyte homing. | Lymphocyte binding to endothelium is a necessary prerequisite for lymphocyte homing through endothelium. This is mediated by the binding of ligands on endothelial cells to lymphocyte surface homing receptors. We show in this paper that the intracellular second messenger pathways involved in interferon gamma-induced int... | 10.1016/0198-8859(90)90010-m | 1,972,149 | D000818:Animals; D002448:Cell Adhesion; D015815:Cell Adhesion Molecules; D002465:Cell Movement; D002478:Cells, Cultured; D004730:Endothelium, Vascular; D006084:Graft Rejection; D006801:Humans; D007249:Inflammation; D018799:Intercellular Adhesion Molecule-1; D008214:Lymphocytes; D051381:Rats; D011919:Rats, Inbred Strain... | Human immunology | 1,990 | D015815:Cell Adhesion Molecules; D018799:Intercellular Adhesion Molecule-1 |
Wildlife Pathology Studies and How They Can Inform Public Health. | Emerging zoonoses have had a serious impact on human and animal health in recent decades. More often than not, these disease outbreaks have taken public health by surprise because we have failed to shift the epidemiological curve to the far left and detect zoonoses in animal populations prior to spillover to people. No... | 10.1093/ilar/ilv043 | 26,912,717 | D000818:Animals; D001717:Birds; D002685:Chiroptera; D021821:Communicable Diseases, Emerging; D004196:Disease Outbreaks; D019142:Hemorrhagic Fever, Ebola; D011634:Public Health; D000072739:Sentinel Species; D014901:West Nile Fever; D015047:Zoonoses | ILAR journal | 2,016 | |
In Silico Analysis of Homologous Heterodimers of Cruzipain-Chagasin from Structural Models Built by Homology. | The present study gives an overview of the binding energetics of the homologous heterodimers of cruzipain-chagasin based on the binding energy (ΔGb) prediction obtained with FoldX. This analysis involves a total of 70 homologous models of the cruzipain-chagasin complex which were constructed by homology from the combin... | 10.3390/ijms20061320 | 30,875,920 | D000595:Amino Acid Sequence; D001665:Binding Sites; D003198:Computer Simulation; D003546:Cysteine Endopeptidases; D006801:Humans; D008958:Models, Molecular; D046912:Multiprotein Complexes; D011485:Protein Binding; D011487:Protein Conformation; D015800:Protozoan Proteins; D040681:Structural Homology, Protein; D014349:Tr... | International journal of molecular sciences | 2,019 | D046912:Multiprotein Complexes; D015800:Protozoan Proteins; C435145:chagasin, Trypanosoma; D003546:Cysteine Endopeptidases; C063214:cruzipain |
Unsupervised Deep Learning for Bayesian Brain MRI Segmentation. | Probabilistic atlas priors have been commonly used to derive adaptive and robust brain MRI segmentation algorithms. Widely-used neuroimage analysis pipelines rely heavily on these techniques, which are often computationally expensive. In contrast, there has been a recent surge of approaches that leverage deep learning ... | 10.1007/978-3-030-32248-9_40 | 32,432,231 | Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention | 2,019 | ||
A Multi-faceted Intervention Aimed at Black-White Disparities in the Treatment of Early Stage Cancers: The ACCURE Pragmatic Quality Improvement trial. | BACKGROUND
Reports continue to show that Blacks with curable lung or breast cancer complete treatment less often than similar Whites contributing to worse survival. ACCURE is an intervention trial designed to address this problem.
PATIENTS AND METHODS
A pragmatic, quality improvement trial comparing an intervention g... | 10.1016/j.jnma.2019.03.001 | 30,928,088 | D001741:Black or African American; D054625:Healthcare Disparities; D006801:Humans; D008175:Lung Neoplasms; D008875:Middle Aged; D058996:Quality Improvement; D012189:Retrospective Studies; D044465:White People | Journal of the National Medical Association | 2,020 | |
Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells. | Human infection with highly pathogenic avian influenza viruses (HPAIV) is often associated with severe tissue damage due to hyperinduction of interferons and proinflammatory cytokines. The reasons for this excessive cytokine expression are still incompletely understood, which has hampered the development of efficient i... | 10.3389/fimmu.2018.02229 | 30,323,812 | D000072283:A549 Cells; D000704:Analysis of Variance; D000818:Animals; D064113:CRISPR-Cas Systems; D002522:Chlorocebus aethiops; D000071457:DEAD Box Protein 58; D004847:Epithelial Cells; D055785:Gene Knockdown Techniques; D018014:Gene Transfer Techniques; D057809:HEK293 Cells; D061307:Human Umbilical Vein Endothelial Ce... | Frontiers in immunology | 2,018 | D011971:Receptors, Immunologic; D016899:Interferon-beta; C101116:TRIM28 protein, human; D000076183:Tripartite Motif-Containing Protein 28; D038744:Ribosomal Protein S6 Kinases, 90-kDa; C116919:mitogen and stress-activated protein kinase 1; D048051:p38 Mitogen-Activated Protein Kinases; C452820:RIGI protein, human; D000... |
In vivo detection of iron and neuromelanin by transcranial sonography: a new approach for early detection of substantia nigra damage. | Early diagnosis of Parkinson's disease (PD) in nonsymptomatic patients is a key issue. An increased echogenicity of the substantia nigra (SN) was found previously in Parkinsonian patients and in a low percentage of healthy adults. These nonsymptomatic subjects also showed a reduced 18F-dopa uptake in striatum, suggesti... | 10.1002/mds.20550 | 15,986,424 | D001052:Apoferritins; D042241:Early Diagnosis; D005260:Female; D005293:Ferritins; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007501:Iron; D008297:Male; D008543:Melanins; D008875:Middle Aged; D009410:Nerve Degeneration; D010300:Parkinson Disease; D019275:Radiopharmaceuticals; D013378:Substantia Nigra; D017585:Ultr... | Movement disorders : official journal of the Movement Disorder Society | 2,005 | D008543:Melanins; D019275:Radiopharmaceuticals; C014121:neuromelanin; D019788:Fluorodeoxyglucose F18; D005293:Ferritins; D001052:Apoferritins; D007501:Iron |
Role of Multimodal Cerebral Oximetry Monitoring in the Anesthetic Management of a Patient With High-Grade Intracranial Arteriovenous Malformation: A Case Report. | Near-infrared spectroscopy (NIRS) is a noninvasive monitor of regional brain tissue oxygenation, and jugular venous oximetry (SjvO2) is a monitor of global cerebral oxygenation. We report the role of intraoperative multimodal monitoring of cerebral oxygenation in the anesthetic management of a patient with grade III in... | 10.1213/XAA.0000000000001192 | 32,784,313 | D000777:Anesthetics; D002560:Cerebrovascular Circulation; D006801:Humans; D002538:Intracranial Arteriovenous Malformations; D007601:Jugular Veins; D010092:Oximetry | A&A practice | 2,020 | D000777:Anesthetics |
Inhibition of polymorphonuclear leukocyte chemotaxis by the mucoid exopolysaccharide of Pseudomonas aeruginosa. | We tested the effect on human polymorphonuclear leukocyte (PMN) chemotaxis of the mucoid exopolysaccharide (MEP) elaborated by Pseudomonas aeruginosa strain P1M recovered from the sputum of a patient with cystic fibrosis (CF). A dose-related inhibition of chemotaxis under agarose was observed when mucoid exopolysacchar... | 2,971,496 | D002634:Chemotaxis, Leukocyte; D003550:Cystic Fibrosis; D006025:Glycosaminoglycans; D006801:Humans; D066298:In Vitro Techniques; D009504:Neutrophils; D011135:Polysaccharides, Bacterial; D011552:Pseudomonas Infections; D011550:Pseudomonas aeruginosa | Clinical and investigative medicine. Medecine clinique et experimentale | 1,988 | D006025:Glycosaminoglycans; D011135:Polysaccharides, Bacterial; C046129:mucoid exopolysaccharide (P aeruginosa) | |
Human Mesenchymal Stromal Cell (MSC) Characteristics Vary Among Laboratories When Manufactured From the Same Source Material: A Report by the Cellular Therapy Team of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative. | BACKGROUND
Culture-derived mesenchymal stromal cells (MSCs) exhibit variable characteristics when manufactured using different methods and different source materials. The purpose of this study was to assess the impact on MSC characteristics when different laboratories propagated MSCs from cultures initiated with BM ali... | 10.3389/fcell.2020.00458 | 32,612,991 | Frontiers in cell and developmental biology | 2,020 | ||
Neuropeptide Y Y1 receptor effects on pulpal nociceptors. | Neuropeptide Y (NPY) is an important modulatory neuropeptide that regulates several physiological systems, including the activity of sensory neurons. We evaluated whether activation of the NPY Y1 receptor could modulate the activity of capsaicin-sensitive nociceptors in trigeminal ganglia and dental pulp. We tested thi... | 10.1177/154405910808701008 | 18,809,749 | D000818:Animals; D015740:Calcitonin Gene-Related Peptide; D002211:Capsaicin; D003782:Dental Pulp; D008297:Male; D020078:Neurogenic Inflammation; D009619:Nociceptors; D051381:Rats; D017207:Rats, Sprague-Dawley; D017476:Receptors, Neuropeptide Y; D050916:TRPV Cation Channels; D014098:Toothache; D012668:Trigeminal Ganglio... | Journal of dental research | 2,008 | D017476:Receptors, Neuropeptide Y; D050916:TRPV Cation Channels; C493922:Trpv1 protein, rat; D015740:Calcitonin Gene-Related Peptide; D002211:Capsaicin |
Colicin types of Shigella sonnei in relation to antibiotic resistance. | Colicin typing of 436 strains of Shigella sonnei isolated in Dallas during a 10-year period was performed to determine whether resistance to ampicillin was associated with a single strain or was widespread among all S. sonnei types. One hundred ninety-three strains collected during a period of eight and one-half years... | 10.1093/infdis/132.3.307 | 1,099,149 | D000328:Adult; D000667:Ampicillin; D002648:Child; D003087:Colicins; D005260:Female; D006801:Humans; D008297:Male; D010403:Penicillin Resistance; D012764:Shigella sonnei | The Journal of infectious diseases | 1,975 | D003087:Colicins; D000667:Ampicillin |
Creatine kinase isoenzyme of high relative molecular mass in serum of a cancer patient. | We describe an atypical serum creatine kinase isoenzyme in the serum of a woman with cancer of the left breast. This isoenzyme migrated toward the cathode, closely following the MM isoenzyme on agarose gel electrophoresis. Its relative molecular mass was estimated to be about 325,000, fourfold that of normal creatine k... | 709,848 | D001943:Breast Neoplasms; D003402:Creatine Kinase; D004587:Electrophoresis, Agar Gel; D005260:Female; D006801:Humans; D007527:Isoenzymes; D008875:Middle Aged; D008970:Molecular Weight | Clinical chemistry | 1,978 | D007527:Isoenzymes; D003402:Creatine Kinase | |
Management of anastomotic ulcers after Roux-en-Y gastric bypass: results of an international survey. | BACKGROUND
Anastomotic ulcers (AUs) after Roux-en-Y gastric bypass (RYGB) occur in up to 16% of patients. In an international survey among members of the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO), current preventative and therapeutic strategies in AU were analyzed.
METHODS
An ... | 10.1007/s11695-013-1152-3 | 24,347,350 | D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D015390:Gastric Bypass; D016481:Helicobacter Infections; D016480:Helicobacter pylori; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid; D011183:Postoperative Complications; D017410:Practice Guidelines as Topic; D010... | Obesity surgery | 2,014 | D054328:Proton Pump Inhibitors |
Quality Assessment of Published Systematic Reviews in High Impact Cardiology Journals: Revisiting the Evidence Pyramid. | Objective: Systematic reviews are increasingly used as sources of evidence in clinical cardiology guidelines. In the present study, we aimed to assess the quality of published systematic reviews in high impact cardiology journals. Methods: We searched PubMed for systematic reviews published between 2010 and 2019 in fiv... | 10.3389/fcvm.2021.671569 | 34,179,136 | Frontiers in cardiovascular medicine | 2,021 | ||
Assessment of Adipose Tissue from Whole Body 3T MRI Scans. | Accurate assessment of total body and the distribution of regional adipose tissue is a critical problem emerging in the United States. Using manual segmentation of MRI scanned images is a problem due to the high variation between manual delineations. Manual segmentation also requires highly trained experts with knowled... | 10.1109/IEMBS.2005.1616120 | 17,281,889 | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference | 2,005 | ||
The rise of regulatory RNA. | Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence suggests that RNA is not only functional as a messenger between DNA and protein but also involved in the regulation of genome organization and gene expression, which is increasingly elaborate in complex organisms. Regulatory RNA se... | 10.1038/nrg3722 | 24,776,770 | D000818:Animals; D044127:Epigenesis, Genetic; D019143:Evolution, Molecular; D015894:Genome, Human; D006801:Humans; D022661:RNA, Untranslated | Nature reviews. Genetics | 2,014 | D022661:RNA, Untranslated |
Acylation of N-p-Toluenesulfonylpyrrole Under Friedel-Crafts Conditions. Evidence for Organoaluminum Intermediates. | The Friedel-Crafts acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions has been reinvestigated. Evidence is presented in support of the hypothesis that when AlCl(3) is used as the Lewis acid, acylation proceeds via reaction of an organoaluminum intermediate with the acyl halide. This leads to the pr... | 10.1016/j.tet.2007.12.043 | 19,247,425 | Tetrahedron | 2,008 | ||
Application of outcome measures in international humanitarian aid: comparing indices through retrospective analysis of corrective surgical care cases. | It is common for international organizations to provide surgical corrective care to vulnerable populations in developing countries. However, a current worsening of the overall surgical burden of disease in developing countries reflects an increasing lack of sufficient numbers of trained healthcare personnel, and render... | 10.1017/s1049023x0000652x | 19,557,956 | D000293:Adolescent; D000533:Altruism; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007391:International Cooperation; D008297:Male; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D013518:Surgery, Plastic; D013514:Surgical Procedures, Operative; D05581... | Prehospital and disaster medicine | 2,009 | |
Melanotic neuroectodermal tumor of infancy. | A case of melanotic neuroectodermal tumor of infancy was presented. This tumor occurred in the right maxillary alveolar ridge of 3-month-old female infant, showing bluish enlargement of alveolar mucosa with the displacement of central deciduous incisor. We described the gross, microscopic, and ultrastructural findings ... | 10.3346/jkms.1986.1.1.63 | 2,856,802 | D005260:Female; D006801:Humans; D007223:Infant; D008441:Maxillary Neoplasms; D009373:Neoplasms, Germ Cell and Embryonal | Journal of Korean medical science | 1,986 | |
Investigation of the lipids of saprophytic mycobacteria in the U.S.S.R. | Three trends in the investigations of the specific lipids of rhodococci and related microorganisms are reflected: isolation and structural determination of new complex lipids, elucidation of the role of specific lipids in the cells and application of lipid composition for diagnostic studies of rhodococci and related or... | 10.1016/s0021-9673(00)94553-9 | 3,042,799 | D008055:Lipids; D009161:Mycobacterium; D014586:USSR | Journal of chromatography | 1,988 | D008055:Lipids |
The use of specialized enteral formulas in pulmonary disease. | The relationship between pulmonary disease and nutrition is significant. Malnutrition and its associated adverse pulmonary effects can directly affect outcomes in the individual with pulmonary disease. The use of nutrition support is common for these patients as a supportive or therapeutic measure. Historical reports o... | 10.1177/0115426504019006557 | 16,215,154 | Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition | 2,004 | ||
Can virtual reality increase the realism of role plays used to teach college women sexual coercion and rape-resistance skills? | The present study evaluated whether virtual reality (VR) can enhance the realism of role plays designed to help college women resist sexual attacks. Sixty-two female undergraduate students were randomly assigned to either the Role Play (RP) or Virtual Role Play (VRP) conditions, which were differentiated only by the us... | 10.1016/j.beth.2008.09.002 | 19,892,079 | D000293:Adolescent; D000328:Adult; D003198:Computer Simulation; D005260:Female; D006801:Humans; D015999:Multivariate Analysis; D018579:Patient Selection; D012381:Role Playing; D012742:Sex Offenses; D012984:Software; D011795:Surveys and Questionnaires; D014584:User-Computer Interface | Behavior therapy | 2,009 | |
Identification of the receptors for prolactin-releasing peptide (PrRP) and Carassius RFamide peptide (C-RFa) in chickens. | Prolactin-releasing peptide (PrRP) and its structurally related peptide, Carassius Arg-Phe-amide peptide (C-RFa), have been reported to play similar roles in regulating food intake and pituitary functions in vertebrates. However, the identity, functionality, and expression of the receptor(s) for PrRP and C-RFa remain l... | 10.1210/en.2011-1719 | 22,355,069 | D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain; D002642:Chick Embryo; D002645:Chickens; D002874:Chromosome Mapping; D017868:Cyclic AMP-Dependent Protein Kinases; D018076:DNA, Complementary; D005786:Gene Expression Regulation; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D009479:Neuropepti... | Endocrinology | 2,012 | D018076:DNA, Complementary; D009479:Neuropeptides; C416987:RFamide peptide; D018013:Receptors, Neuropeptide; C400801:receptor, prolactin-releasing peptide; D017868:Cyclic AMP-Dependent Protein Kinases |
Frailty and quality of life for people with Alzheimer's dementia and mild cognitive impairment. | BACKGROUND
Our aim was to investigate the relationship between frailty and health-related quality of life (HR-QOL) in cognitively impaired elderly individuals.
METHODS
A cross-sectional observational study of a convenience sample of 115 patients with a diagnosis of Alzheimer's dementia or mild cognitive impairment. F... | 10.1177/1533317511435661 | 22,467,414 | D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease; D060825:Cognitive Dysfunction; D003430:Cross-Sectional Studies; D003704:Dementia; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012720:Severity of Illness Index | American journal of Alzheimer's disease and other dementias | 2,012 | |
Integration of a Kampo medicine, Nijutsuto, and Western medical treatment in the treatment of long-term frozen shoulder refractory to Western medical treatment: a case series. | OBJECTIVE
Frozen shoulder is a common disorder in general orthopedic practice, characterized by spontaneous onset of pain in the shoulder and accompanied by limitation of glenohumeral movement. Treatments for frozen shoulder include shoulder exercise, manual therapy, corticosteroid injection, manipulation under anesthe... | 10.1177/2156587214568346 | 25,613,331 | D000368:Aged; D000369:Aged, 80 and over; D002062:Bursitis; D005260:Female; D006801:Humans; D008297:Male; D008519:Medicine, Traditional; D008875:Middle Aged; D012189:Retrospective Studies | Journal of evidence-based complementary & alternative medicine | 2,015 | |
Comparative Anatomy of Phagocytic and Immunological Synapses. | The generation of phagocytic cups and immunological synapses are crucial events of the innate and adaptive immune responses, respectively. They are triggered by distinct immune receptors and performed by different cell types. However, growing experimental evidence shows that a very close series of molecular and cellula... | 10.3389/fimmu.2016.00018 | 26,858,721 | Frontiers in immunology | 2,016 | ||
Cycloparaphenylenes and Their Catenanes: Complex Macrocycles Unveiled by Ion Mobility Mass Spectrometry. | The insoluble product mixture obtained from cycloparaphenylene (CPP) synthesis from Suzuki coupling and reductive aromatization was analyzed. Traditional mass spectrometry suggests a homologous series of macrocycles with 12 to 84 phenylene units. Ion-mobility mass spectrometry, however, unravels an unexpected complexit... | 10.1002/anie.201611943 | 28,146,311 | Angewandte Chemie (International ed. in English) | 2,017 | ||
Nutrition and immune system disorders | INTRODUCTION
Energy and nutrients obtained through food play an important role in the development and preservation of the immune system therefore any nutritional imbalance affects its competence and integrity.
OBJECTIVES
Knowing the nutritional approach on different disorders of the immune system.
METHODS
A review ... | 10.20960/nh.1575 | 29,156,936 | D006801:Humans; D007107:Immune System; D007154:Immune System Diseases; D009748:Nutrition Disorders; D009747:Nutritional Physiological Phenomena; D009752:Nutritional Status; D014815:Vitamins | Nutricion hospitalaria | 2,017 | D014815:Vitamins |
Trajectory mapping of primary Sjögren's syndrome via transcriptome learning demonstrates limitations of peripheral blood sequencing. | Primary Sjögren's syndrome (pSS) is a complex autoimmune disease characterized by aberrant immune cell action against secretory glands throughout the body. A number of studies have previously identified unique characteristics in the circulating expression profile of white blood cells of pSS patients. However, the molec... | 10.1111/1756-185X.14229 | 34,668,328 | D016208:Databases, Factual; D020869:Gene Expression Profiling; D006801:Humans; D015398:Signal Transduction; D012859:Sjogren's Syndrome | International journal of rheumatic diseases | 2,021 | |
Oral eltrombopag versus subcutaneous recombinant human thrombopoietin for promoting platelet engraftment after allogeneic stem cell transplantation: A prospective, non-inferiority, randomized controlled trial. | Delayed platelet engraftment (DPE) is associated with poor survival and increased transplantation-related mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Therefore, treatments are needed to improve platelet engraftment and prevent DPE. We performed a phase three, non-inferior, randomized... | 10.1002/hon.3017 | 35,554,955 | D001565:Benzoates; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D006834:Hydrazines; D011446:Prospective Studies; D011720:Pyrazoles; D011994:Recombinant Proteins; D013926:Thrombopoietin | Hematological oncology | 2,022 | D001565:Benzoates; D006834:Hydrazines; D011720:Pyrazoles; D011994:Recombinant Proteins; D013926:Thrombopoietin; C520809:eltrombopag |
The lost infant: impact on the family. | Stillbirth, sudden infant death syndrome, death of a premature infant or death of an infant through disease give rise grieving processes with many features in common. Feelings, particularly between the parents, and between parents and surviving children, must be dealt with if the grief reaction is to achieve a normal r... | 21,293,723 | Canadian family physician Medecin de famille canadien | 1,980 | |||
A methodology for setting practice criteria in healthcare. | Practice criteria are an important part of health care and have taken a new prominence in the trend to address quality-of-care issues. Once an organisation makes a commitment to addressing its quality-of-care, it must define 'quality' in operational terms. Practice criteria do just that. The organisation ensures consis... | 10.1177/146642409911900210 | 11,043,006 | D003906:Developing Countries; D006298:Health Services Administration; D006801:Humans; D011785:Quality Assurance, Health Care | The journal of the Royal Society for the Promotion of Health | 1,999 | |
Sterilizers and the medical device directive. | There are a number of important issues currently facing the European Commission on the interpretation and implementation of the Medical Device Directive (MDD). One of these concerns medical device sterilizers used in hospitals, physicians' or dentists' offices, or other medical settings, and whether they should be reg... | 10,147,069 | D005060:Europe; D006801:Humans; D013242:Sterilization; D014481:United States; D014486:United States Food and Drug Administration | Medical device technology | 1,994 | ||
A newly designed template device for use with the insertion of immediately loaded implants. | This article describes a newly designed surgical template that was used to facilitate dental implant placement. The implants were planned to function by loading them immediately. A case report describing the device and the benefits of its use for a patient with an edentulous mandible is presented. Four implants were pl... | 10.1563/0711.1 | 15,587,024 | D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D005260:Female; D006801:Humans; D007575:Jaw, Edentulous; D008875:Middle Aged | The Journal of oral implantology | 2,004 | D015921:Dental Implants |
The chinese version of the decisional balance scale: further validation. | BACKGROUND
Although the Decisional Balance Scale (DBS) has been established to have sound psychometric properties, the reliability and validity of this instrument have not been evaluated in different populations.
OBJECTIVES
The aim of this study was to conduct psychometric validations for the Chinese version of the D... | 10.1097/00006199-200607000-00002 | 16,849,974 | D000293:Adolescent; D044466:Asian People; D002648:Child; D002755:Choice Behavior; D003430:Cross-Sectional Studies; D003657:Decision Making; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D011581:Psychological Tests; D015203:Reproducibility of Results; D012907:Smoking; D013624:Taiwan | Nursing research | 2,006 | |
Activity of striatal neurons reflects dynamic encoding and recoding of procedural memories. | Learning to perform a behavioural procedure as a well-ingrained habit requires extensive repetition of the behavioural sequence, and learning not to perform such behaviours is notoriously difficult. Yet regaining a habit can occur quickly, with even one or a few exposures to cues previously triggering the behaviour. To... | 10.1038/nature04053 | 16,237,445 | D000161:Acoustic Stimulation; D000200:Action Potentials; D000818:Animals; D001479:Basal Ganglia; D001522:Behavior, Animal; D003463:Cues; D005108:Extinction, Psychological; D006184:Habits; D018782:Maze Learning; D008568:Memory; D009473:Neuronal Plasticity; D009474:Neurons; D051381:Rats; D012201:Reward | Nature | 2,005 | |
Alveolate and chlorophycean mitochondrial cox2 genes split twice independently. | The mitochondrial gene for COXII is typically encoded in the organelle genome, however in some members of two unrelated groups, Apicomplexa and Chlorophyceae, cox2 is split into two genes, and both are encoded in the nucleus. Rare genomic changes (RGCs) have acquired popularity as phylogenetic markers, and accordingly ... | 10.1016/j.gene.2006.07.003 | 16,987,614 | D000818:Animals; D016782:Apicomplexa; D000460:Chlorophyta; D004141:Dinoflagellida; D003576:Electron Transport Complex IV; D019143:Evolution, Molecular; D020224:Expressed Sequence Tags; D022761:Gene Transfer, Horizontal; D050259:Genes, Mitochondrial; D017125:Genes, Protozoan; D008969:Molecular Sequence Data; D010802:Phy... | Gene | 2,006 | C117108:cytochrome C oxidase subunit II; D003576:Electron Transport Complex IV |
An experimental study of hematoma formation after arterial and venous puncture. | Hematoma formation following the puncture of femoral veins or arteries of dogs was determined using mercury-filled strain gauges. Arterial bleeding always produced a hematoma. The duration of the swelling was prolonged if heparin was previously administered. Bleeding from the femoral vein did not produce a hematoma unl... | 10.1016/0278-2391(83)90128-3 | 6,575,144 | D000818:Animals; D001158:Arteries; D001794:Blood Pressure; D003187:Compliance; D004285:Dogs; D005260:Female; D006406:Hematoma; D008297:Male; D011677:Punctures; D013997:Time Factors; D014680:Veins; D014690:Venous Pressure | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons | 1,983 | |
Assessment of the glucose tolerance test in unselected pregnancy using 75 g glucose load. | A 75 g oral glucose tolerance test (OGTT) was performed in 618 unselected pregnant Chinese women between 24 and 28 weeks gestation. The glucose response at fasting, 1, 2 and 3 h were studied. At 2 h the glucose level at 2-standard deviation and 4-standard deviation above the mean came very close to the criteria of abno... | 10.1016/0020-7292(88)90080-x | 2,905,302 | D000328:Adult; D003920:Diabetes Mellitus; D005260:Female; D005947:Glucose; D005951:Glucose Tolerance Test; D006801:Humans; D011247:Pregnancy; D011254:Pregnancy in Diabetics; D014944:World Health Organization | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics | 1,988 | D005947:Glucose |
Synthesis and SAR comparison of regioisomeric aryl naphthyridines as potent mGlu5 receptor antagonists. | We describe three novel regioisomeric series of aryl naphthyridine analogs, which are potent antagonists of the Class III GPCR mGlu5 receptor. The synthesis and in vitro and in vivo pharmacological activities of these analogs are discussed. | 10.1016/j.bmcl.2007.09.083 | 17,936,624 | D000818:Animals; D016466:CHO Cells; D006224:Cricetinae; D003412:Cricetulus; D009287:Naphthyridines; D051381:Rats; D064529:Receptor, Metabotropic Glutamate 5; D018094:Receptors, Metabotropic Glutamate; D013237:Stereoisomerism; D013329:Structure-Activity Relationship | Bioorganic & medicinal chemistry letters | 2,007 | D009287:Naphthyridines; D064529:Receptor, Metabotropic Glutamate 5; D018094:Receptors, Metabotropic Glutamate |
The functional importance of hydrophobicity of the tyrosine at position 13 of human epidermal growth factor in receptor binding. | The tyrosine at position 13 of epidermal growth factor (EGF) has been implicated as playing a role in receptor binding due to its close proximity to the critical arginine 41 residue as well as its high degree of conservation in EGF and EGF-like proteins that can bind to the EGF receptor. Site-directed mutagenesis of ty... | 8,486,681 | D000595:Amino Acid Sequence; D001483:Base Sequence; D001667:Binding, Competitive; D002942:Circular Dichroism; D004815:Epidermal Growth Factor; D066246:ErbB Receptors; D006801:Humans; D007700:Kinetics; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D009838:Oligodeoxyribonucleotides; D016133:Polymer... | The Journal of biological chemistry | 1,993 | D009838:Oligodeoxyribonucleotides; D011994:Recombinant Proteins; D014443:Tyrosine; D004815:Epidermal Growth Factor; D066246:ErbB Receptors | |
Effects of white and infrared lighting on apomorphine-induced pecking in pigeons. | This experiment was concerned with the role of the environment in the production and form of apomorphine-induced pecking of pigeons. Earlier literature has suggested that the pecking occurs even when pigeons are placed in complete darkness, but there are no systematic or quantitative reports of such pecking. Six pigeon... | 10.1097/FBP.0b013e32830990ac | 18,622,183 | D000818:Animals; D001058:Apomorphine; D010856:Columbidae; D018491:Dopamine Agonists; D004305:Dose-Response Relationship, Drug; D005247:Feeding Behavior; D007259:Infrared Rays; D008027:Light; D008297:Male; D014741:Video Recording | Behavioural pharmacology | 2,008 | D018491:Dopamine Agonists; D001058:Apomorphine |
Reductions in Management Distress Following a Randomized Distress Intervention Are Associated With Improved Diabetes Behavioral and Glycemic Outcomes Over Time. | OBJECTIVE
To explore associations between reductions in diabetes distress (DD) and improvements in glycemic outcomes among adults with type 1 diabetes (T1D) in the context of a DD randomized clinical trial.
RESEARCH DESIGN AND METHODS
Adults with T1D (N = 301) participated in a two-arm trial aimed at reducing DD (DD-... | 10.2337/dc20-2724 | 33,990,376 | D000328:Adult; D001786:Blood Glucose; D015190:Blood Glucose Self-Monitoring; D003922:Diabetes Mellitus, Type 1; D006442:Glycated Hemoglobin; D006801:Humans; D007003:Hypoglycemia; D007328:Insulin; D008875:Middle Aged | Diabetes care | 2,021 | D001786:Blood Glucose; D006442:Glycated Hemoglobin A; D007328:Insulin |
Lead exposure among small-scale battery recyclers, automobile radiator mechanics, and their children in Manila, the Philippines. | Blood lead (PbB) and hemoglobin levels (Hb) were determined in 40 battery repair/recycling shop workers, 16 radiator repair shop workers, and 20 children living in the immediate vicinity of these shops. Unexposed residents with similar socioeconomic status were also investigated. Mean PbB level was significantly higher... | 10.1006/enrs.1999.4024 | 10,702,330 | D000328:Adult; D000740:Anemia; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure; D005192:Family Health; D005260:Female; D006454:Hemoglobins; D006801:Humans; D007854:Lead; D008297:Male; D008875:Middle Aged; D018986:Motor Vehicles; D016273:Occupational Exposure; D010679:Philippines; D014018:Tissue ... | Environmental research | 2,000 | D006454:Hemoglobins; D007854:Lead |
[Asymmetry of the latent periods of saccades in human depending on visual space complicity]. | Saccadic latencies of visually-guided saccades of 10 right-handed subjects with right-leading eyes were studied. Stimulation paradigm was spatially bidimentional, and stimuli were shown along horizontal and vertical meridians. Three traditional single step GAP - NO DELAY - OVERLAP temporal paradigms were used. In the f... | 16,756,127 | D000293:Adolescent; D000328:Adult; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D010775:Photic Stimulation; D012438:Saccades; D014794:Visual Fields | Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova | 2,006 | ||
First Report of Powdery Mildew Caused by Podosphaera xanthii on Verbena brasiliensis in Korea. | Verbena brasiliensis Vell., commonly known as Brazilian verbena, is native to South America and has been introduced into North America, coastal Europe, southern Africa, and Australasia. Though partly cultivated for garden use, it is invasive in riverine areas and also on roadsides, forest margins, pastures, and waste a... | 10.1094/PDIS-02-14-0195-PDN | 30,708,802 | Plant disease | 2,014 | ||
[Research progress of exploring the treatment of sepsis based on cholinergic anti-inflammatory pathway]. | The cholinergic anti-inflammatory pathway (CAP) is an important neuroimmunomodulatory mechanism that innervates the spleen through vagus nerve efferent and splenic nerve relay, and acts on macrophages by transforming adrenergic stimulation into cholinergic signal by spleen T cells, which plays an anti-inflammatory effe... | 10.3760/cma.j.cn121430-20200421-00318 | 33,565,416 | D006801:Humans; D007249:Inflammation; D015213:Neuroimmunomodulation; D018805:Sepsis; D013154:Spleen; D014630:Vagus Nerve; D055536:Vagus Nerve Stimulation | Zhonghua wei zhong bing ji jiu yi xue | 2,021 | |
Formation of iminium ions by fragmentation of a2 ions. | Tandem mass spectrometric experiments have been carried out on the protonated amides H-Gly-Ala-NH2, H-Ala-Gly-NH2, H-Ala-Val-NH2, H-Val-Ala-pNA, H-Leu-Phe-NH2, H-Phe-Leu-NH2, H-Phe-Tyr-NH2 and H-Tyr-Phe-NH2 with particular emphasis on the fragmentation of the isomeric a2 ions derived therefrom. Primary fragmentation re... | 10.1002/rcm.1532 | 15,282,790 | D008401:Gas Chromatography-Mass Spectrometry; D007097:Imines; D008958:Models, Molecular; D008968:Molecular Conformation; D009842:Oligopeptides; D011522:Protons; D021241:Spectrometry, Mass, Electrospray Ionization | Rapid communications in mass spectrometry : RCM | 2,004 | D007097:Imines; D009842:Oligopeptides; D011522:Protons |
A Retrospective Study on the Efficacy of Two Different Rehabilitation Interventions on KOA: Shock Wave Therapy vs. Electroacupuncture Therapy. | OBJECTIVE
In this paper, we retrospectively reviewed the difference in clinical effectiveness of shock wave therapy and electroacupuncture therapy on knee osteoarthritis.
METHODS
A total of 128 treatment cases of knee osteoarthritis patients were extracted from the medical record system of Shenzhen Longhua District C... | 10.1155/2021/2099653 | 34,881,332 | D015669:Acupuncture Points; D015670:Acupuncture Therapy; D003131:Combined Modality Therapy; D015671:Electroacupuncture; D000074059:Extracorporeal Shockwave Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee; D012189:Retrospective Studies; D016896:Treatment Outcome | BioMed research international | 2,021 | |
Ultrasound-guided neurosurgery: a feasibility study in the 3-30 MHz frequency range. | This study, which includes seven patients, illustrates some potential values of the interactive use of ultrasound technology prior to, during and after brain tumour resection. Ultrasound B-scan and colour flow imaging were applied during open surgery using a cardiac scanner in the 3.25-7.5 MHz frequency range and an in... | 10.1080/02688699650040313 | 8,861,307 | D000328:Adult; D000368:Aged; D001254:Astrocytoma; D001783:Blood Flow Velocity; D001932:Brain Neoplasms; D004453:Echoencephalography; D004867:Equipment Design; D005260:Female; D005909:Glioblastoma; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008577:Meningeal Neoplasms; D008579:Meningioma;... | British journal of neurosurgery | 1,996 | |
The novel NO-donating compound GIT-27NO inhibits in vivo growth of human prostate cancer cells and prevents murine immunoinflammatory hepatitis. | We investigated the effects of the recently synthetized NO donating agent GIT-27NO on the growth of human androgen independent and androgen dependent PC3 and LnCap cells xenografted in nude mice. We also tested the effects of GIT-27NO in the preclinical model of cell-mediated immunoinflammatory hepatitis that can be in... | 10.1016/j.ejphar.2009.04.069 | 19,446,546 | D000085:Acetates; D000818:Animals; D000970:Antineoplastic Agents; D045744:Cell Line, Tumor; D002470:Cell Survival; D003208:Concanavalin A; D005260:Female; D019693:Hepatitis, Autoimmune; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008819:Mice, Nude; D009368:Neo... | European journal of pharmacology | 2,009 | C518641:3-phenyl-4,5-dihydro-5-isoxazole acetic acid; D000085:Acetates; D000970:Antineoplastic Agents; D020030:Nitric Oxide Donors; D010080:Oxazoles; D003208:Concanavalin A |
Familial erythrophagocytic lymphohistiocytosis in infancy. | A 2 1/2-month-old infant suffering from pyrexia, purpura, hepatosplenomegaly, pancytopenia and hyperlipidemia is reported. Liver and spleen biopsies revealed mononuclear histiocytic infiltration with marked erythrophagocytosis. The girl died at 7 1/2 months of age. Her brother died in infancy with an analogous clinical... | 10.1007/BF00441930 | 7,227,396 | D003241:Consanguinity; D004912:Erythrocytes; D005260:Female; D006801:Humans; D007223:Infant; D008206:Lymphatic Diseases; D008297:Male; D010587:Phagocytosis | European journal of pediatrics | 1,981 | |
Characterizing endourologist learning curve during percutaneous nephrolithotomy: implications on occupational dose and patients. | In this study we have characterized the learning curve of percutaneous nephrolithotomy procedures over 301 cases for six years. Different surrogate parameters of clinical expertise have been used, such as dose area product, total procedure time, fluoroscopy time and personal equivalent doses. In addition, two different... | 10.1088/1361-6498/aa8e51 | 28,936,986 | Journal of radiological protection : official journal of the Society for Radiological Protection | 2,017 | ||
Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling. | The urogenital and reproductive organs, including the external genitalia, bladder and urethra, develop as anatomically aligned organs. Descriptive and experimental embryology suggest that the cloaca, and its derivative, the urogenital sinus, contribute to the formation of these organs. However, it is unknown how the pr... | 10.1242/dev.02736 | 17,202,190 | D000818:Animals; D001483:Base Sequence; D004247:DNA; D018507:Gene Expression Regulation, Developmental; D053823:Hedgehog Proteins; D006801:Humans; D051741:Kruppel-Like Transcription Factors; D008648:Mesoderm; D051379:Mice; D008810:Mice, Inbred C57BL; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic; D009130:Muscl... | Development (Cambridge, England) | 2,007 | C498520:Gli1 protein, mouse; D053823:Hedgehog Proteins; D051741:Kruppel-Like Transcription Factors; D000072079:Patched Receptors; D011956:Receptors, Cell Surface; D000071676:Zinc Finger Protein GLI1; D013629:Tamoxifen; D004247:DNA |
Drug use evaluation approach to monitoring use of total parenteral nutrition: a review of criteria for use in cancer patients. | Monitoring of total parenteral nutrition (TPN) by drug use evaluation appears to be a reasonable approach to characterizing use of parenteral nutrition within an institution. Development of specific criteria for use of TPN may be difficult because of the broad nature of published guidelines. Criteria for use of TPN in ... | 10.1177/0115426593008005233 | 8,302,256 | D002985:Clinical Protocols; D017277:Drug Approval; D016903:Drug Monitoring; D006801:Humans; D009369:Neoplasms; D010289:Parenteral Nutrition, Total | Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition | 1,993 |
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