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Statistical approaches for evaluating surrogate outcomes in clinical trials: A systematic review. | The use of surrogate outcomes that predict treatment effect on an unobserved true outcome may have substantial economic and ethical advantages, through reducing the length and size of clinical trials. There has been extensive investigation of the best means of evaluating putative surrogates. We present a systematic rev... | 10.1080/10543406.2015.1094811 | 26,391,022 | D015415:Biomarkers; D002986:Clinical Trials as Topic; D003627:Data Interpretation, Statistical; D006801:Humans | Journal of biopharmaceutical statistics | 2,016 | D015415:Biomarkers |
Macromolecule functionalization of disulfide-bonded polymer hydrogel capsules and cancer cell targeting. | We present a generic and versatile method for functionalization of disulfide-stabilized PMA hydrogel capsules (HCs) with macromolecules, including a number of specific antibodies to cancer cells. Functionalization was achieved by reversible addition-fragmentation chain transfer (RAFT) polymerization of poly(N-vinyl pyr... | 10.1021/nn204319b | 22,260,171 | D000906:Antibodies; D001360:Avidin; D001710:Biotin; D002214:Capsules; D045744:Cell Line, Tumor; D004220:Disulfides; D004337:Drug Carriers; D006801:Humans; D020100:Hydrogels; D008958:Models, Molecular; D008968:Molecular Conformation; D058105:Polymerization; D011109:Polymethacrylic Acids; D011205:Povidone | ACS nano | 2,012 | D000906:Antibodies; D002214:Capsules; D004220:Disulfides; D004337:Drug Carriers; D020100:Hydrogels; D011109:Polymethacrylic Acids; D001360:Avidin; C030613:polymethacrylic acid; D001710:Biotin; D011205:Povidone |
Differentiating Motor Coordination in Children with Cerebral Palsy and Typically Developing Populations Through Exploratory Factor Analysis of Robotic Assessments. | General motor and executive functions are integral for tasks of daily living and are typically assessed when quantifying impairment of an individual. Robotic tasks offer highly repeatable and objective measures of motor and cognitive function. Additionally, robotic tasks and measures have been used successfully to quan... | 10.1109/EMBC46164.2021.9630740 | 34,892,470 | D002547:Cerebral Palsy; D002648:Child; D005163:Factor Analysis, Statistical; D006801:Humans; D011597:Psychomotor Performance; D065287:Robotic Surgical Procedures; D012371:Robotics | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 2,021 | |
SUMOylation of AnxA6 facilitates EGFR-PKCα complex formation to suppress epithelial cancer growth. | BACKGROUND
The Annexin A6 (AnxA6) protein is known to inhibit the epidermal growth factor receptor (EGFR)-extracellular signal regulated kinase (ERK)1/2 signaling upon EGF stimulation. While the biochemical mechanism of AnxA6 inactivating phosphorylation of EGFR and ERK1/2 is not completely explored in cancer cells.
... | 10.1186/s12964-023-01217-x | 37,528,485 | D006801:Humans; D000818:Animals; D051379:Mice; D066246:ErbB Receptors; D000077156:Gefitinib; D017317:Annexin A6; D018773:Genes, erbB-1; D006367:HeLa Cells; D051571:Protein Kinase C-alpha; D058207:Sumoylation; D008819:Mice, Nude; D002853:Chromatography, Liquid; D004815:Epidermal Growth Factor; D045744:Cell Line, Tumor; ... | Cell communication and signaling : CCS | 2,023 | D066246:ErbB Receptors; D000077156:Gefitinib; D017317:Annexin A6; D051571:Protein Kinase C-alpha; D004815:Epidermal Growth Factor; D047428:Protein Kinase Inhibitors; C512478:EGFR protein, human |
Analysis of local recurrence of midrectal cancer after low anterior resection and stapled anastomosis. | We evaluated local recurrences of midrectal cancer in 33 patients treated with low anterior resection and stapled end-to-end anastomosis. All patients had follow-up for at least 2 years or until death. There were 21 men and 12 women. Data were analyzed with attention to Astler-Coller modified Dukes' stage, distal margi... | 10.1097/00007611-199205000-00010 | 1,585,203 | D000714:Anastomosis, Surgical; D005260:Female; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012004:Rectal Neoplasms; D013528:Surgical Staplers | Southern medical journal | 1,992 | |
[Research advances of extramedullary relapse in multiple myeloma - review]. | Multiple myeloma (MM) is a malignant plasma cell disorder characterized by the abnormal expansion and accumulation of clonal plasma cells in the bone marrow in association with production of monoclonal immunoglobulin and its fragment (as protein), and MM remains an incurable disease. Recently extramedullary relapse of ... | 23,114,161 | D006801:Humans; D009101:Multiple Myeloma; D012008:Recurrence | Zhongguo shi yan xue ye xue za zhi | 2,012 | ||
The influence of smoking on recovery from subacromial pain syndrome: a cohort from the Military Health System. | BACKGROUND
Smoking rates are higher in the military population than in the civilian sector. Smoking is associated with poor prognosis for many musculoskeletal injuries. The purpose of this study was to investigate the effects of smoking on recovery from a shoulder injury in a prospective cohort seeking care at a milita... | 29,214,618 | D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008889:Military Personnel; D026741:Physical Therapy Modalities; D011446:Prospective Studies; D020069:Shoulder Pain; D012907:Smoking; D016896:Treatment Outcome; D055815:Young Adult | U.S. Army Medical Department journal | 2,017 | ||
Low Expression of ICAM-1 in Blood Eosinophils in Patients With Active Eosinophilic Esophagitis. | BACKGROUND AND OBJECTIVE
Eosinophilic esophagitis (EoE) is a chronic and isolated inflammation of the esophagus characterized by a marked infiltration of eosinophilic leukocytes. Diagnosis and course of the disease are based exclusively on histopathology. Therefore, patients must undergo several esophageal biopsies, im... | 10.18176/jiaci.0489 | 31,983,676 | D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D001706:Biopsy; D001773:Blood Cells; D015536:Down-Regulation; D057765:Eosinophilic Esophagitis; D004804:Eosinophils; D004947:Esophagus; D005260:Female; D006801:Humans; D018799:Intercellular Adhesion Molecule-1; D008297:Male; D008875:Middle Aged; D055815:Young Adult | Journal of investigational allergology & clinical immunology | 2,021 | D015415:Biomarkers; D018799:Intercellular Adhesion Molecule-1 |
Investigation of respiratory and ion transport properties of aging bean stem slices. | Ion and oxygen uptake were studied on aging bean stem slices. Oxygen uptake was high immediately after slicing, decreased to a minimum at 100 minutes, and then increased again. Ion uptake per unit of O(2) uptake data suggested that metabolic energy was utilized almost exclusively for sodium transport in fresh tissue bu... | 10.1104/pp.47.5.663 | 16,657,680 | Plant physiology | 1,971 | ||
Within- and between-generation effects of temperature on early fecundity of Drosophila melanogaster. | We used a repeated-measures, four-factor experimental design to determine how the fecundity of Drosophila melanogaster during the first 5 days of adult life was influenced by paternal, maternal, developmental and laying temperature, with two different temperature levels (18 degrees C vs. 25 degrees C) per factor. Layin... | 10.1038/hdy.1995.30 | 7,706,111 | D000818:Animals; D004331:Drosophila melanogaster; D005260:Female; D005298:Fertility; D008297:Male; D010063:Ovum; D013696:Temperature | Heredity | 1,995 | |
Clinical Impact of ASCO Choosing Wisely Guidelines on Staging Imaging for Early-Stage Breast Cancers: A Time Series Analysis Using SEER-Medicare Data. | PURPOSE
American Society for Clinical Oncology released the Choosing Wisely list in 2012, highlighting low-value procedures that lack evidence, advising against the use of positron emission tomography, computerized tomography, and radionuclide bone scans for the staging of early-stage breast cancer at low risk for meta... | 10.1200/OP.22.00500 | 36,375,114 | D006801:Humans; D005260:Female; D000368:Aged; D014481:United States; D001943:Breast Neoplasms; D013997:Time Factors; D006278:Medicare; D014057:Tomography, X-Ray Computed; D049268:Positron-Emission Tomography | JCO oncology practice | 2,023 | |
Fracture strength and energy-dispersive spectroscopy analysis of 3-unit fixed partial dentures fabricated from different monolithic zirconia materials. | STATEMENT OF PROBLEM
Mastication forces in different regions affect the survival of multiunit posterior restorations. The fracture strength of 3-unit posterior monolithic zirconia fixed partial dentures (FPDs) and their fracture patterns require investigation.
PURPOSE
The purpose of this in vitro study was to evaluat... | 10.1016/j.prosdent.2023.03.011 | 37,024,356 | D000077298:Flexural Strength; D008422:Materials Testing; D003799:Dental Stress Analysis; D003830:Denture, Partial, Fixed; D015040:Zirconium; D013057:Spectrum Analysis; D019232:Dental Restoration Failure; D003776:Dental Porcelain | The Journal of prosthetic dentistry | 2,023 | C028541:zirconium oxide; D015040:Zirconium; D003776:Dental Porcelain |
The application of monoclonal antibodies to the diagnosis of disseminated mycoses. | Monoclonal antibodies (MoAbs) have had a major impact on many areas of biomedical research and almost since their advent have been used in the characterisation and identification of diagnostically important antigens of fungal pathogens. Their main significance lies in three, often inter-related areas: a) the definition... | 18,473,530 | Revista iberoamericana de micologia | 1,998 | |||
Cell therapy for Parkinson's disease: problems and prospects. | Cell replacement therapy in Parkinson's disease (PD) has so far been based on the use of primary dopaminergic (DA) neuroblasts obtained from the brain of aborted human fetuses. Clinical trials show that intrastriatal DA neuron transplants can give substantial symptomatic relief in advanced PD patients. Two recent NIH-s... | 16,050,257 | D002454:Cell Differentiation; D004298:Dopamine; D006801:Humans; D009474:Neurons; D010300:Parkinson Disease; D033581:Stem Cell Transplantation | Novartis Foundation symposium | 2,005 | D004298:Dopamine | |
Automated bioacoustic identification of species. | Research into the automated identification of animals by bioacoustics is becoming more widespread mainly due to difficulties in carrying out manual surveys. This paper describes automated recognition of insects (Orthoptera) using time domain signal coding and artificial neural networks. Results of field recordings made... | 10.1590/s0001-37652004000200037 | 15,258,662 | D000162:Acoustics; D000818:Animals; D001330:Electronic Data Processing; D016571:Neural Networks, Computer; D009987:Orthoptera; D006113:United Kingdom; D014828:Vocalization, Animal | Anais da Academia Brasileira de Ciencias | 2,004 | |
An inter-laboratory ring trial for the detection and isolation of Mycobacterium avium subsp. paratuberculosis from raw milk artificially contaminated with naturally infected faeces. | There is a need for standardised, robust, reproducible molecular and culture methods to achieve clarification of the inactivation of Mycobacterium avium subsp. paratuberculosis (Map), the causative microbial agent of Johne's disease, in (faecally) contaminated milk and other food products such as meat. This study asses... | 10.1016/j.fm.2007.06.007 | 17,993,386 | D000818:Animals; D002417:Cattle; D019411:Clinical Laboratory Techniques; D015169:Colony Count, Microbial; D003257:Consumer Product Safety; D004269:DNA, Bacterial; D005243:Feces; D005506:Food Contamination; D005784:Gene Amplification; D006801:Humans; D008892:Milk; D016927:Mycobacterium avium subsp. paratuberculosis; D01... | Food microbiology | 2,008 | D004269:DNA, Bacterial; D011933:Reagent Kits, Diagnostic |
The Short-Term Effects of Joint Mobilizations on Acute Mechanical Low Back Dysfunction in Collegiate Athletes. | Context: Although a variety of theories and studies have been cited to support the use of joint mobilization in the spine as an integral part of the treatment and rehabilitation process, information about the short-term effects of joint mobilization on acute low back injury with respect to patient pain and strength cha... | 15,970,954 | Journal of athletic training | 2,005 | |||
CodY Regulates the Activity of the Virulence Quorum Sensor PlcR by Controlling the Import of the Signaling Peptide PapR in Bacillus thuringiensis. | In Gram-positive bacteria, cell-cell communication mainly relies on cytoplasmic sensors of the RNPP family. Activity of these regulators depends on their binding to secreted signaling peptides that are imported into the cell. These quorum sensing regulators control important biological functions in bacteria of the Baci... | 10.3389/fmicb.2015.01501 | 26,779,156 | Frontiers in microbiology | 2,015 | ||
Procalcitonin in Preterm Neonates: A Different Threshold and Prolonged Interpretation. | Objectives: To evaluate the positive threshold of PCT for neonates of <32 weeks of gestation for the diagnosis of early-onset sepsis and to determine if the level of PCT collected within 6 h of life could be used. Design: Retrospective and bicentric study from May 2016 to April 2018. Setting: Two groups were establishe... | 10.3389/fped.2021.623043 | 34,079,778 | Frontiers in pediatrics | 2,021 | ||
Comparison of Open and Ultrasound-Guided Placement of Central Venous Catheter in Children Weighing Less Than Five Kilograms; A Randomized Clinical Trial. | OBJECTIVES
Ultrasound is currently utilized to locate the internal jugular vein (IJV), reduce the complications of catheter placement, and increase the likelihood of accessing IJV. Therefore, the aim of the present study was to evaluate the effectiveness of ultrasound in reducing complications during catheter placement... | 10.1016/j.acra.2022.10.010 | 36,446,685 | D006801:Humans; D002648:Child; D062905:Central Venous Catheters; D002405:Catheterization, Central Venous; D014463:Ultrasonography; D013927:Thrombosis; D018084:Ultrasonography, Interventional | Academic radiology | 2,023 | |
Sleep, Circadian Rhythms, and Cognitive Dysfunction in Huntington's Disease. | BACKGROUND
In healthy people, sleep and circadian disruption are linked to cognitive deficits. People with Huntington's disease (HD), who have compromised brain function and sleep and circadian disturbances, may be even more susceptible to these cognitive effects.
OBJECTIVE
To conduct a comprehensive review and synth... | 10.3233/JHD-230578 | 37,599,535 | D006801:Humans; D006816:Huntington Disease; D002940:Circadian Rhythm; D012890:Sleep; D003072:Cognition Disorders; D060825:Cognitive Dysfunction | Journal of Huntington's disease | 2,023 | |
Comparison of impedance and strain gauge plethysmography in the measurement of blood flow in the lower limb. | Simultaneous measurement of the flow of blood in the calf in 24 normal volunteers by impedance and mercury strain gauge plethysmography has revealed a systematic difference in the results from the two methods. Possible reasons for this discrepancy are discussed. | 10.1002/bjs.1800621113 | 1,191,954 | D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D008628:Mercury; D008875:Middle Aged; D010991:Plethysmography; D010992:Plethysmography, Impedance; D012039:Regional Blood Flow | The British journal of surgery | 1,975 | D008628:Mercury |
[Influence of cadmium on the course of intestinal and muscular phases in mice infected with Trichinella spiralis]. | At the first experiment 20 Swiss male mice were infected with 100 larvae and 20 mice with 500 larvae T. spiralis per mouse. Two days after infection (d.a.i.) mice orally received 1.5 mg Cd (water solution CdCl2) each. 40 mice were infected only T. spiralis as control. At the second experiment muscle larvae used were is... | 1,299,056 | D000818:Animals; D002104:Cadmium; D007421:Intestine, Small; D007814:Larva; D008297:Male; D051379:Mice; D009132:Muscles; D017160:Trichinella spiralis | Wiadomosci parazytologiczne | 1,992 | D002104:Cadmium | |
An Unusual Presentation of SCAD in a Young Male Soldier. | Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic cause of myocardial infarction and sudden cardiac death in young individuals without significant cardiovascular risk factors. The etiology of SCAD appears to be multifactorial and is often precipitated by physical and emotional stress superimposed o... | 10.1093/milmed/usad347 | 37,651,581 | Military medicine | 2,023 | ||
[Forensic-medical assessment of intraocular pressure change for estimation of the time since death]. | Based on analyses of 756 intraocular pressure (IOP) measurements in different terms of postmortal period, it was established that decrease in IOP occurred simultaneously with increase in prescription of death coming and had its own pattern, which could be described with mathematical formulas, resulting from fundamental... | 18,589,665 | D005123:Eye; D049429:Forensic Pathology; D006801:Humans; D007429:Intraocular Pressure; D011180:Postmortem Changes; D013997:Time Factors; D014065:Tonometry, Ocular | Sudebno-meditsinskaia ekspertiza | 2,008 | ||
Resveratrol Ameliorates Fibrosis in Rheumatoid Arthritis-Associated Interstitial Lung Disease via the Autophagy-Lysosome Pathway. | Interstitial lung disease associated with rheumatoid arthritis (RA-ILD) can lead to interstitial fibrosis and even lung failure as a complication of rheumatoid arthritis (RA), and there is currently no effective treatment and related basic research. Studies have found that resveratrol (Res) can improve the progression ... | 10.3390/molecules27238475 | 36,500,562 | D000818:Animals; D000077185:Resveratrol; D017563:Lung Diseases, Interstitial; D001172:Arthritis, Rheumatoid; D005355:Fibrosis; D011658:Pulmonary Fibrosis; D001343:Autophagy | Molecules (Basel, Switzerland) | 2,022 | D000077185:Resveratrol |
Family planning and Afghan refugee women and men living in Melbourne, Australia: new opportunities and transcultural tensions. | This research aimed to explore the family planning perspectives and experiences of Afghan women and men living in Melbourne. A total of 57 Afghan women and men participated in six focus groups and 20 semi-structured interviews. The majority of participants indicated a preference for two or three children and were open ... | 10.1080/13691058.2019.1643498 | 31,354,105 | D000328:Adult; D000346:Afghanistan; D001315:Australia; D003267:Contraception; D005191:Family Characteristics; D005193:Family Planning Services; D005260:Female; D017144:Focus Groups; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D036301:Qua... | Culture, health & sexuality | 2,020 | |
Energy metabolism in human renin-gene transgenic rats: does renin contribute to obesity? | Renin initiates angiotensin II formation and has no other known functions. We observed that transgenic rats (TGR) overexpressing the human renin gene (hREN) developed moderate obesity with increased body fat mass and glucose intolerance compared with nontransgenic Sprague-Dawley (SD) rats. The metabolic changes were no... | 10.1161/HYPERTENSIONAHA.108.124966 | 19,171,793 | D017667:Adipocytes; D000577:Amides; D000804:Angiotensin II; D000818:Animals; D002478:Cells, Cultured; D004195:Disease Models, Animal; D004734:Energy Metabolism; D005650:Fumarates; D006801:Humans; D020738:Leptin; D050356:Lipid Metabolism; D008297:Male; D009765:Obesity; D010641:Phenotype; D051381:Rats; D017207:Rats, Spra... | Hypertension (Dallas, Tex. : 1979) | 2,009 | D000577:Amides; D005650:Fumarates; D020738:Leptin; D000804:Angiotensin II; C446481:aliskiren; D012083:Renin |
Body mass index and association with use of and distance from places for physical activity and active leisure among schoolchildren in Brazil. Cross-sectional study. | BACKGROUND
We evaluated associations between use of public places for physical activity and active leisure (PAAL) and their distances from subjects' homes and indicators of overweight and obesity, among schoolchildren from different socioeconomic levels, in the city of Florianópolis, Brazil.
DESIGN AND SETTING
Cross-... | 10.1590/1516-3180.2017.0347020118 | 29,924,287 | D000293:Adolescent; D015992:Body Mass Index; D001938:Brazil; D002648:Child; D003430:Cross-Sectional Studies; D015444:Exercise; D005260:Female; D006801:Humans; D007182:Income; D007899:Leisure Activities; D008297:Male; D063766:Pediatric Obesity; D012959:Socioeconomic Factors; D000072264:Sports and Recreational Facilities... | Sao Paulo medical journal = Revista paulista de medicina | 2,018 | |
Registration in the supine position improve the accuracy of cup placement in total hip arthroplasty using a portable navigation system. | Portable navigation systems have been developed for use in total hip arthroplasty (THA) in recent years. Although intraoperative registration in the lateral decubitus position or the supine position is need to create the three-dimensional coordinate system, it is not clear which position is appropriate. The purpose of ... | 10.1038/s41598-023-47674-9 | 37,980,455 | D006801:Humans; D019644:Arthroplasty, Replacement, Hip; D006622:Hip Prosthesis; D016683:Supine Position; D000077:Acetabulum; D012189:Retrospective Studies; D025321:Surgery, Computer-Assisted | Scientific reports | 2,023 | |
Use of kisspeptin to trigger oocyte maturation during in vitro fertilisation (IVF) treatment. | Infertility is a major global health issue and is associated with significant psychological distress for afflicted couples. In vitro fertilisation (IVF) utilises supra-physiological doses of stimulatory hormones to induce the growth of multiple ovarian follicles to enable surgical retrieval of several oocytes for subse... | 10.3389/fendo.2022.972137 | 36,147,569 | D006063:Chorionic Gonadotropin; D005260:Female; D005307:Fertilization in Vitro; D007987:Gonadotropin-Releasing Hormone; D006801:Humans; D059648:Kisspeptins; D007986:Luteinizing Hormone; D009865:Oocytes; D016471:Ovarian Hyperstimulation Syndrome; D011247:Pregnancy | Frontiers in endocrinology | 2,022 | D006063:Chorionic Gonadotropin; D059648:Kisspeptins; D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone |
Targeted Drug Delivery and Treatment of Endoparasites with Biocompatible Particles of pH-Responsive Structure. | Biomaterials conceived for vectorization of bioactives are currently considered for biomedical, biological, and environmental applications. We have produced a pH-sensitive biomaterial composed of natural source alginate and chitosan polysaccharides for application as a drug delivery system via oral administration. The ... | 10.1021/acs.biomac.7b01630 | 29,283,560 | D000464:Alginates; D000818:Animals; D001672:Biocompatible Materials; D002397:Catfishes; D048271:Chitosan; D003692:Delayed-Action Preparations; D005393:Fish Diseases; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D006863:Hydrogen-Ion Concentration; D007559:Ivermectin; D008463:Mebendazole; D010272:Parasitic Diseases | Biomacromolecules | 2,018 | D000464:Alginates; D001672:Biocompatible Materials; D003692:Delayed-Action Preparations; D006603:Hexuronic Acids; D007559:Ivermectin; D008463:Mebendazole; D020723:Glucuronic Acid; D048271:Chitosan |
[Apoptosis and apoptosis-related genes in experimental autoimmune inner ear disease]. | OBJECTIVE
To investigate the protein and mRNA expression patterns of apoptosis-related genes, together with evidence of apoptosis, in relation to experimental autoimmune inner ear disease (AIED).
METHODS
Male C57BL/6 mice at 4 weeks age (n = 80) were randomly assigned to one of the five group (n = 16). The inbred mic... | 16,270,868 | D000818:Animals; D017209:Apoptosis; D001327:Autoimmune Diseases; D053222:Fas Ligand Protein; D006168:Guinea Pigs; D020287:In Situ Nick-End Labeling; D007759:Labyrinth Diseases; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D013136:Spira... | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery | 2,005 | D053222:Fas Ligand Protein; C491899:Fas protein, mouse; C505658:Fasl protein, mouse; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D019014:fas Receptor; C052617:Bcl2 protein, mouse | |
Practice Bulletin No. 165: Prevention and Management of Obstetric Lacerations at Vaginal Delivery. | Lacerations are common after vaginal birth. Trauma can occur on the cervix, vagina, and vulva, including the labial, periclitoral, and periurethral regions, and the perineum. Most of these lacerations do not result in adverse functional outcomes. Severe perineal lacerations, extending into or through the anal sphincter... | 10.1097/AOG.0000000000001523 | 27,333,357 | D036861:Delivery, Obstetric; D004841:Episiotomy; D005260:Female; D005836:Genitalia, Female; D006801:Humans; D022125:Lacerations; D007744:Obstetric Labor Complications; D010346:Patient Care Management; D010502:Perineum; D011247:Pregnancy; D015599:Trauma Severity Indices; D014481:United States | Obstetrics and gynecology | 2,016 | |
Lymphocytoplasmapheresis in multiple sclerosis: preliminary laboratory findings. | Short-term treatment with lymphocytoplasmapheresis was evaluated in 6 multiple sclerosis patients with special reference to the electrophysiological and immunological findings. Visual, somatosensory, brainstem auditory evoked potentials, flicker fusion test, helper/suppressor blood lymphocyte ratio, serum immunocomplex... | 10.1007/BF02229223 | 3,997,466 | D000328:Adult; D005071:Evoked Potentials; D005260:Female; D005425:Flicker Fusion; D006801:Humans; D008214:Lymphocytes; D008297:Male; D009103:Multiple Sclerosis; D010956:Plasmapheresis | Italian journal of neurological sciences | 1,985 | |
Sphingosine-1-phosphate: a novel nonhypoxic activator of hypoxia-inducible factor-1 in vascular cells. | OBJECTIVE
Sphingosine-1-phosphate (S1P) is a potent bioactive phospholipid responsible for a variety of vascular cell responses. Hypoxia-inducible factor-1 (HIF-1) is a transcriptional activator of genes essential for adaptation to low oxygen. S1P and HIF-1 are both important mediators of vascular cell responses such a... | 10.1161/ATVBAHA.109.185280 | 19,423,865 | D000818:Animals; D002417:Cattle; D015687:Cell Hypoxia; D002467:Cell Nucleus; D002478:Cells, Cultured; D042783:Endothelial Cells; D005786:Gene Expression Regulation; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D008246:Lysophospholipids; D051379:Mice; D009131:Muscle, Smooth, Vascular; D032389:Myocytes, Smooth Musc... | Arteriosclerosis, thrombosis, and vascular biology | 2,009 | C497443:Hif1a protein, mouse; C497444:Hif1a protein, rat; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D008246:Lysophospholipids; D034741:RNA, Small Interfering; D049349:Receptors, Lysosphingolipid; C060506:sphingosine 1-phosphate; D013110:Sphingosine |
Biliary access loops for intrahepatic stones: results of jejunoduodenal anastomosis. | BACKGROUND
Patients with intrahepatic calculi require multiple interventions following successful surgical stone clearance for recurrent stones and cholangitis. The present paper describes the results of a technique of in-continuity side-to-side jejunoduodenal anastomosis (JDA) that provides endoscopic access to the he... | 10.1046/j.1445-2197.2003.t01-1-02623.x | 12,752,287 | D000328:Adult; D000714:Anastomosis, Surgical; D001649:Bile Duct Diseases; D001653:Bile Ducts, Intrahepatic; D002769:Cholelithiasis; D004385:Duodenostomy; D004386:Duodenum; D016145:Endoscopy, Digestive System; D005260:Female; D006801:Humans; D007582:Jejunostomy; D007583:Jejunum; D008297:Male; D008875:Middle Aged; D01706... | ANZ journal of surgery | 2,003 | |
Nucleophilic lewis base dependent addition reactions of allenoates with trifluoromethylated cyclic ketimines. | A detailed investigation on the different reactivity patterns shown by phosphorus- and nitrogen-containing Lewis base catalysts in the reactions of allenoates with cyclic trifluoromethyl ketimines was accomplished. With PPh3, [3 + 2] annulations proceeded smoothly to afford dihydropyrrole derivatives in excellent yield... | 10.1021/jo500356t | 24,693,927 | The Journal of organic chemistry | 2,014 | ||
[Bellini duct carcinoma: report of two cases]. | OBJECTIVE
We report two cases of collecting duct carcinoma that were diagnosed in our hospital in a six-month period.
METHODS/RESULTS
The first case was a 75years-old woman showing in CT scan a mass in the left kidney which infiltrated perinephric fat. The second case was a 72-years-old that showed in a CT scan a rig... | 18,581,680 | D000368:Aged; D002292:Carcinoma, Renal Cell; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms; D007685:Kidney Tubules, Collecting; D008297:Male; D012082:Renal Veins; D014682:Vena Cava, Inferior | Archivos espanoles de urologia | 2,008 | ||
Discovery of a polysaccharide from the fruiting bodies of Lepista sordida as potent inhibitors of indoleamine 2, 3-dioxygenase (IDO) in HepG2 cells via blocking of STAT1-mediated JAK-PKC-δ signaling pathways. | The present study examined the role of a polysaccharide (LSP, 25 and 100 μg/ml) from the fruiting bodies of Lepista sordid on the immunosuppressive enzyme indoleamine 2, 3-dioxygenase (IDO) in HepG2 cells, and the possible mechanism of action. IDO expression and kynurenine production from LSP-treated HepG2 cells follow... | 10.1016/j.carbpol.2018.05.052 | 30,007,645 | D000818:Animals; D004305:Dose-Response Relationship, Drug; D055808:Drug Discovery; D004791:Enzyme Inhibitors; D048690:Fruiting Bodies, Fungal; D056945:Hep G2 Cells; D006801:Humans; D050503:Indoleamine-Pyrrole 2,3,-Dioxygenase; D053613:Janus Kinase 1; D000076244:Lepisma; D011134:Polysaccharides; D051745:Protein Kinase C... | Carbohydrate polymers | 2,018 | D004791:Enzyme Inhibitors; D050503:Indoleamine-Pyrrole 2,3,-Dioxygenase; D011134:Polysaccharides; D050794:STAT1 Transcription Factor; C494079:STAT1 protein, human; C507904:JAK1 protein, human; D053613:Janus Kinase 1; D051745:Protein Kinase C-delta |
[Lymphoblastic lymphoma in children. Poor response in advanced disease with chemotherapy for non-Hodgkin's lymphoma]. | Fifty three pediatric patients with the histopathological diagnosis of lymphoblastic lymphoma (LL) were studied in a retrospective analysis during a 14 year period. Their age ranged from 1 to 16 years with a median of 7 years. Clinical staging was performed according to Murphy's system. There was one child in stage I (... | 7,839,017 | D000206:Actuarial Analysis; D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008228:Lymphoma, Non-Hodgkin; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma; D012189:Retrospective Stud... | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion | 1,994 | ||
Neural indicators of error processing in generalized anxiety disorder, obsessive-compulsive disorder, and major depressive disorder. | The ability to detect and respond to errors is critical to successful adaptation to a changing environment, and variation in error-related brain activity has been linked to psychopathology. The error-related negativity (ERN), an event-related potential component, represents a unique neural response to errors and is gen... | 10.1037/abn0000019 | 25,384,068 | D000328:Adult; D000704:Analysis of Variance; D001008:Anxiety Disorders; D001931:Brain Mapping; D016022:Case-Control Studies; D003865:Depressive Disorder, Major; D004569:Electroencephalography; D005071:Evoked Potentials; D005260:Female; D006179:Gyrus Cinguli; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Ob... | Journal of abnormal psychology | 2,015 | |
Familial acute necrotizing encephalopathy with RANBP2 mutation: The first report in Northeast Asia. | BACKGROUND
Acute necrotizing encephalopathy (ANE) is a rare but rapidly progressing encephalopathy following a febrile illness, commonly a viral infection. It is characterized by the features of acute encephalopathy such as seizure, alteration of consciousness, and symmetric involvement of the bilateral thalamus on neu... | 10.1016/j.braindev.2017.02.005 | 28,336,122 | D044466:Asian People; D001921:Brain; D002675:Child, Preschool; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007723:Korea; D004684:Leukoencephalitis, Acute Hemorrhagic; D018832:Molecular Chaperones; D009154:Mutation; D028861:Nuclear P... | Brain & development | 2,017 | D018832:Molecular Chaperones; D028861:Nuclear Pore Complex Proteins; C094493:ran-binding protein 2 |
Multivariate Metal-Organic Frameworks as Multifunctional Heterogeneous Asymmetric Catalysts for Sequential Reactions. | The search for versatile heterogeneous catalysts with multiple active sites for broad asymmetric transformations has long been of great interest, but it remains a formidable synthetic challenge. Here we demonstrate that multivariate metal-organic frameworks (MTV-MOFs) can be used as an excellent platform to engineer he... | 10.1021/jacs.7b03113 | 28,537,723 | Journal of the American Chemical Society | 2,017 | ||
Clinical deterioration during antitubercular treatment at a district hospital in South Africa: the importance of drug resistance and AIDS defining illnesses. | BACKGROUND
Clinical deterioration on drug therapy for tuberculosis is a common cause of hospital admission in Africa. Potential causes for clinical deterioration in settings of high HIV-1 prevalence include drug resistant Mycobacterium tuberculosis (M.tb), co-morbid illnesses, poor adherence to therapy, tuberculosis as... | 10.1371/journal.pone.0004520 | 19,229,341 | D017088:AIDS-Related Opportunistic Infections; D000163:Acquired Immunodeficiency Syndrome; D000293:Adolescent; D000328:Adult; D000995:Antitubercular Agents; D005260:Female; D015497:HIV-1; D006767:Hospitals, District; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013019:South Africa; D... | PloS one | 2,009 | D000995:Antitubercular Agents |
Neurobehavioral abnormalities in newborns with congenital heart disease requiring open-heart surgery. | In a prospective study, we evaluated the perioperative application of the Neonatal Intensive Care Unit Network Neurobehavioral Scale in a cohort of newborns with congenital heart disease (CHD). Infants with CHD were found to have suboptimal neurobehavioral performance compared with healthy infants without CHD, with par... | 10.1016/j.jpeds.2010.11.060 | 21,232,769 | D002658:Developmental Disabilities; D005260:Female; D006305:Health Status Indicators; D006330:Heart Defects, Congenital; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011446:Prospective Studies; D012044:Regression Analysis | The Journal of pediatrics | 2,011 | |
An efficient de novo synthesis of partially reduced phenanthrenes through C-C insertion. | An efficient and novel approach to the synthesis of highly congested 3-alkyl-, 4-alkyl-, 3-aryl-, 3,4-dialkyl-, 4-alkyl-3-aryl-, and 3,4-diaryl-9,10-dihydro-1-sec-aminophenanthrene-2-carbonitriles has been delineated through the base-catalyzed ring transformation of 5,6-dihydro-2-oxo-4-sec-amino-2H-benzo[h]chromene-3-c... | 10.1021/jo0711079 | 17,705,542 | D009570:Nitriles; D010084:Oxidation-Reduction; D010616:Phenanthrenes | The Journal of organic chemistry | 2,007 | D009570:Nitriles; D010616:Phenanthrenes |
The strategies and outcomes of left subclavian artery revascularization during thoracic endovascular repair for type B aortic dissection. | This study was to analyze the outcomes of left subclavian artery (LSA) revascularization during thoracic endovascular repair (TEVAR) for type B aortic dissections (TBAD). From 2011 to 2017, TBAD patients who underwent LSA revascularization during TEVAR were enrolled. Technical success, endoleaks, mortality, complicatio... | 10.1038/s41598-018-27588-7 | 29,915,242 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection; D001013:Aorta, Thoracic; D057510:Endovascular Procedures; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D013348:Subclavian Artery; D016896:Treatment Outcome | Scientific reports | 2,018 | |
Telehealth and autism: Are telehealth language assessments reliable and feasible for children with autism? | BACKGROUND
Access to timely and appropriate speech-language pathology (SLP) services is a significant challenge for many families. Telehealth has been used successfully to treat a range of communication disorders in children and adults. Research examining the use of telehealth for children with autism has focused large... | 10.1111/1460-6984.12440 | 30,565,791 | D000067877:Autism Spectrum Disorder; D002648:Child; D003147:Communication Disorders; D005260:Female; D006801:Humans; D007807:Language Tests; D008297:Male; D015203:Reproducibility of Results; D013066:Speech-Language Pathology; D017216:Telemedicine | International journal of language & communication disorders | 2,019 | |
Four-Dimensional Stimuli-Responsive Hydrogels Micro-Structured via Femtosecond Laser Additive Manufacturing. | Rapid fabricating and harnessing stimuli-responsive behaviors of microscale bio-compatible hydrogels are of great interest to the emerging micro-mechanics, drug delivery, artificial scaffolds, nano-robotics, and lab chips. Herein, we demonstrate a novel femtosecond laser additive manufacturing process with smart materi... | 10.3390/mi13010032 | 35,056,197 | Micromachines | 2,021 | ||
Glycogen storage disease type IIIa in pregnant women: A guide to management. | Glycogen storage disease type IIIa (GSD-IIIa) is an autosomal recessive disorder that impairs glycogenolysis, producing ketotic hypoglycaemia, hepatomegaly, cardiac and skeletal myopathy. During pregnancy, increased metabolic demand requires careful management. There are few case reports about pregnancy in GSD-IIIa, ho... | 10.1002/jmd2.12282 | 35,433,175 | JIMD reports | 2,022 | ||
New cytotoxic dammarane type saponins from Ziziphus spina-christi. | Cancer is the world's second-leading cause of death. Drug development efforts frequently focus on medicinal plants since they are a valuable source of anticancer medications. A phytochemical investigation of the edible Ziziphus spina-christi (F. Rhamnaceae) leaf extract afforded two new dammarane type saponins identifi... | 10.1038/s41598-023-46841-2 | 37,996,449 | D010936:Plant Extracts; D031957:Ziziphus; D012503:Saponins; D000970:Antineoplastic Agents; D000097669:Dammaranes | Scientific reports | 2,023 | D010936:Plant Extracts; D012503:Saponins; D000970:Antineoplastic Agents |
Mathematical modeling and optimal control of SARS-CoV-2 and tuberculosis co-infection: a case study of Indonesia. | A new mathematical model incorporating epidemiological features of the co-dynamics of tuberculosis (TB) and SARS-CoV-2 is analyzed. Local asymptotic stability of the disease-free and endemic equilibria are shown for the sub-models when the respective reproduction numbers are below unity. Bifurcation analysis is carried... | 10.1007/s40808-022-01430-6 | 35,814,616 | Modeling earth systems and environment | 2,022 | ||
Potential mechanisms underlying the association between type II diabetes mellitus and cognitive dysfunction in rats: a link between miRNA-21 and Resveratrol's neuroprotective action. | Cognitive impairment is considered as a typical feature of neurodegenerative diseases in diabetes mellitus (DM). However, the exact link between cognitive dysfunction and diabetes mellitus is still vague. This study aims to investigate some of the mechanisms underlying cognitive impairment that associates diabetes mell... | 10.1007/s11011-022-01035-z | 35,781,592 | D051381:Rats; D000818:Animals; D013311:Streptozocin; D000077185:Resveratrol; D003924:Diabetes Mellitus, Type 2; D003921:Diabetes Mellitus, Experimental; D060825:Cognitive Dysfunction; D007328:Insulin; D005947:Glucose; D008055:Lipids; D035683:MicroRNAs | Metabolic brain disease | 2,022 | D013311:Streptozocin; D000077185:Resveratrol; D007328:Insulin; D005947:Glucose; D008055:Lipids; D035683:MicroRNAs |
[Revised 2017 Clinical Diagnostic Criteria for Dementia with Lewy Bodies: Inclusion of REM Sleep Behavior Disorder and Indicative Biomarkers]. | Although dementia with Lewy bodies (DLB) is the second most common neurodegenerative disorder after Alzheimer disease, its diagnostic sensitivity in clinical practice is sub-optimal. In 2017, the DLB clinical diagnostic criteria were modified to include the additional core feature of REM sleep behavior disorder (RBD) a... | 10.11477/mf.1416201096 | 30,082,497 | D015415:Biomarkers; D006801:Humans; D016631:Lewy Bodies; D020961:Lewy Body Disease; D020187:REM Sleep Behavior Disorder | Brain and nerve = Shinkei kenkyu no shinpo | 2,018 | D015415:Biomarkers |
30-Day Readmission Following Outpatient Transmetatarsal Amputation in the Geriatric Population: An ACS NSQIP Analysis. | Whether secondary to deformity, traumatic injury, infection, neoplasm, or ischemic disease, the transmetatarsal amputation provides a functional means of limb preservation prior to major proximal amputation. With similar readmission rates following inpatient and outpatient surgery, prevention of an unnecessary admissio... | 10.1053/j.jfas.2023.08.013 | 37,661,019 | The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons | 2,023 | ||
Recombinant phenotyping of cytomegalovirus sequence variants detected after 200 or 100 days of valganciclovir prophylaxis. | BACKGROUND
In a phase III controlled trial IMproved Protection Against Cytomegalovirus in Transplantation (IMPACT) comparing 200 with 100 days of valganciclovir prophylaxis in 318 cytomegalovirus D+/R- kidney transplant recipients, an equal number of patients (n=3 per arm) had known ganciclovir resistance mutations det... | 10.1097/TP.0b013e3181fdd9d2 | 21,030,903 | D000998:Antiviral Agents; D001483:Base Sequence; D003587:Cytomegalovirus; D003586:Cytomegalovirus Infections; D005500:Follow-Up Studies; D015774:Ganciclovir; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006801:Humans; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D013997:Time Fac... | Transplantation | 2,010 | D000998:Antiviral Agents; D000077562:Valganciclovir; D015774:Ganciclovir |
Development of an opto-electronic positioning device for serial direct digital images of oral structures. | The aim of this study was to develop and test in vitro an opto-electronic positioning device for serial direct digital images of oral structures, i.e. to associate direct digital imaging with the principles of computer-aided surgery. This system registered positions of infrared light emitting diodes (LED) on carriers, ... | 10.1034/j.1600-0765.2000.035004225.x | 10,983,883 | D004867:Equipment Design; D006801:Humans; D009055:Mouth; D055095:Optics and Photonics; D019252:Radiography, Dental, Digital; D013382:Subtraction Technique; D013515:Surgery, Oral; D013813:Therapy, Computer-Assisted | Journal of periodontal research | 2,000 | |
Patients' perspective on factors affecting utilization of primary health care centers in Riyadh, Saudi Arabia. | OBJECTIVE
The aim of this study is to assess factors which the patients think can encourage, discourage or have no effect on utilization of Primary Health Care Centers (PHCCs) in Riyadh, Kingdom of Saudi Arabia.
METHODS
Patients (n=540) attending the selected PHCCs in Riyadh were asked regarding their views on 21 (fa... | 12,436,129 | D000293:Adolescent; D000328:Adult; D005260:Female; D006296:Health Services; D006801:Humans; D008297:Male; D008875:Middle Aged; D010361:Patients; D011320:Primary Health Care; D012529:Saudi Arabia | Saudi medical journal | 2,002 | ||
Identification and validation of new quantitative trait loci for spike-related traits in two RIL populations. | Wheat (Triticum aestivum L.) is one of the most important cereal crops for ensuring food security worldwide. Identification of major quantitative trait loci (QTL) for spike-related traits is important for improvement of yield potential in wheat breeding. In this study, by using the wheat 55K single nucleotide polymorph... | 10.1007/s11032-023-01401-4 | 37,533,603 | Molecular breeding : new strategies in plant improvement | 2,023 | ||
Effects of temperature and antibody on the cyclid growth of vesicular stomatitis virus. | To see the effects of temperature on the interrelated cyclic production of standard and defective interfering (DI) particles of vesicular stomatitis virus, a temperature-sensitive (ts) G114 mutant was passaged successively at different temperatures and the production of the two types of viral particles as well as the a... | 10.1128/JVI.21.1.161-167.1977 | 189,064 | D000818:Animals; D000914:Antibodies, Viral; D002460:Cell Line; D006224:Cricetinae; D003673:Defective Viruses; D005260:Female; D009154:Mutation; D010053:Ovary; D010507:Periodicity; D013696:Temperature; D014721:Vesicular stomatitis Indiana virus; D014762:Viral Interference; D014779:Virus Replication | Journal of virology | 1,977 | D000914:Antibodies, Viral |
The pregnancy rates with intrauterine insemination (IUI) in superovulated cycles employing different protocols (clomiphen citrate (CC), human menopausal gonadotropin (HMG) and HMG+CC) and in natural ovulatory cycle. | OBJECTIVE
To compare the result of IUI in infertile couples with different protocols of induction ovulation.
METHODS
In a retrospective study, 209 infertile couples with different diagnosis (unexplained, male factor, endometriosis, tubal disease, ovulatory dysfunction and multifactorial infertility) were subjected to... | 15,552,282 | D002996:Clomiphene; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007246:Infertility; D007315:Insemination, Artificial; D008297:Male; D008596:Menotropins; D010060:Ovulation; D010062:Ovulation Induction; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies | JPMA. The Journal of the Pakistan Medical Association | 2,004 | D002996:Clomiphene; D008596:Menotropins | |
Content overlap inflates the relation between negative cognition and dysphoria. | We investigated whether the presence of items assessing negative cognition on the Beck Depression Inventory (BDI) inflates the relation between BDI scores and measures of negative cognition. In four student samples, we examined the relation between measures of self-esteem, dysfunctional attitudes, control beliefs, perc... | 10.1207/s15327752jpa6002_16 | 8,473,974 | D000293:Adolescent; D001290:Attitude; D003863:Depression; D005260:Female; D006801:Humans; D007389:Internal-External Control; D008297:Male; D010555:Personality Inventory; D011594:Psychometrics; D012649:Self Concept; D012944:Social Support | Journal of personality assessment | 1,993 | |
Differences in clinical manifestations in patients with bicuspid and tricuspid aortic valves undergoing surgery of the aortic valve and/or ascending aorta. | A bicuspid aortic valve is found in approximately 2 % of the population. The data in the literature concerning the incidence of clinical manifestations are inconsistent, and a detailed comparison with patients with tricuspid aortic valve is not yet available. We analyzed the clinical manifestations and demographic data... | 10.1055/s-2007-965387 | 18,027,333 | D000367:Age Factors; D000368:Aged; D001013:Aorta, Thoracic; D017545:Aortic Aneurysm, Thoracic; D001021:Aortic Valve; D006348:Cardiac Surgical Procedures; D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012... | The Thoracic and cardiovascular surgeon | 2,007 | |
Pharmaceutical high profits: the value of R&D, or oligopolistic rents? | Pharmaceutical firms attribute high prices and high profits to costs associated with researching and developing the next generation of life-saving drugs. Using data from annual reports, this article tests the validity of this claim. We find that while pharmaceutical firms do invest in R&D, they also enjoy strong rents;... | 10.1111/j.1536-7150.2011.00820.x | 22,319,815 | D016527:Drug Costs; D004345:Drug Industry; D004467:Economics; D017048:Health Care Costs; D049673:History, 20th Century; D049674:History, 21st Century; D004364:Pharmaceutical Preparations; D012106:Research; D014481:United States | American journal of economics and sociology | 2,012 | D004364:Pharmaceutical Preparations |
Oncology nurses' responses to patient-initiated humor. | The purpose of this study was to investigate potential predictors (patient variables) that would result in oncology nurses' recognition of and response to patient-initiated humor (PIH). Participants included 47 nurses of an 80-member Oncology Nursing Society chapter (57% response rate), which yielded 232 usable vignett... | 10.1097/01.NCC.0000339243.51291.cc | 18,987,502 | D000704:Analysis of Variance; D003142:Communication; D003710:Demography; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D008297:Male; D015233:Models, Statistical; D009369:Neoplasms; D009723:Nurse-Patient Relations; D009859:Oncology Nursing; D010865:Pilot Projects; D012044:Regression Analysis; D011795:Surv... | Cancer nursing | 2,008 | |
Evoker: a visualization tool for genotype intensity data. | SUMMARY
Genome-wide association studies (GWAS), which produce huge volumes of data, are now being carried out by many groups around the world, creating a need for user-friendly tools for data quality control (QC) and analysis. One critical aspect of GWAS QC is evaluating genotype cluster plots to verify sensible genoty... | 10.1093/bioinformatics/btq280 | 20,507,892 | D003196:Computer Graphics; D030541:Databases, Genetic; D055106:Genome-Wide Association Study; D005838:Genotype; D020407:Internet; D020641:Polymorphism, Single Nucleotide; D012984:Software | Bioinformatics (Oxford, England) | 2,010 | |
Vitamin A deficiency and hepatic retinol levels in sea otters, Enhydra lutris. | Vitamin A deficiency has rarely been reported in captive or free-ranging wildlife species. Necropsy findings in two captively housed southern sea otters (Enhydra lutris nereis) included irregular thickening of the calvaria characterized by diffuse hyperostoses on the internal surface. One animal also had moderate squam... | 10.1638/2010-0010.1 | 22,946,376 | D000822:Animal Husbandry; D000818:Animals; D000836:Animals, Zoo; D019587:Dietary Supplements; D005260:Female; D008099:Liver; D010041:Otters; D014801:Vitamin A; D014802:Vitamin A Deficiency | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians | 2,011 | D014801:Vitamin A |
Seroepidemiological survey of rubella immunity among three populations in Shiraz, Islamic Republic of Iran. | We used indirect ELISA assay to test 1193 sera for rubella IgG and IgM antibodies in a seroepidemiological survey of three age- and gender-differentiated sample populations in Shiraz: 203 children aged 2-7 years, 255 paired mothers and neonates (cord blood) and 480 women aged 14-70 years. Seropositivity among women age... | 12,596,962 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005312:Fetal Blood; D006801:Humans; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007492:Iran; D008875:Middle ... | Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit | 2,001 | D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012411:Rubella Vaccine | |
Quantifying the rebinding effect in multivalent chemical ligand-receptor systems. | Multivalent ligand-receptor systems often show an enhancement in binding compared to the constituent monovalent systems. This "cooperativity effect" is often attributed to the favorable spatial preorganisation of the ligands by the connecting spacer that leads to a reduction of entropy loss at ligand binding. A differe... | 10.1063/1.4739501 | 22,894,336 | D019277:Entropy; D007700:Kinetics; D008024:Ligands; D008390:Markov Chains; D011336:Probability | The Journal of chemical physics | 2,012 | D008024:Ligands |
An observational descriptive survey of rosacea in the Chinese population: clinical features based on the affected locations. | BACKGROUND
There is currently no study that has evaluated the differences in epidemiological and clinical characteristics among rosacea patients according to different facial sites.
METHODS
Clinical and demographic data were obtained from 586 rosacea patients. The patients were divided into four groups based on the m... | 10.7717/peerj.3527 | 28,698,821 | PeerJ | 2,017 | ||
Aneurysms of the hand: Imaging and surgical technique. | Hand aneurysms are a rare entity only described as case reports in the literature. The aim of our study was to describe a series of four cases and the surgical technique using an arterial bypass. We also wanted to define an algorithm for the imaging of this pathology. We have operated on four patients with hand aneurys... | 10.1016/j.hansur.2018.02.002 | 29,567,084 | D000328:Adult; D000714:Anastomosis, Surgical; D000783:Aneurysm; D001158:Arteries; D003952:Diagnostic Imaging; D005260:Female; D006225:Hand; D006801:Humans; D008297:Male; D008875:Middle Aged | Hand surgery & rehabilitation | 2,018 | |
Sarafotoxin 6c protects against ischaemia-induced cardiac arrhythmias in vivo and in vitro in the rat. | The aim of this study was to investigate whether the endothelin-B- (ETB) receptor agonist sarafotoxin 6c (S6c) can protect against ischaemia-induced cardiac arrhythmias. Arrhythmias were induced by a 30 min period of coronary artery occlusion in pentobarbitone-anaesthetized male rats, or in Langendorff-perfused rat hea... | 10.1097/00005344-200036051-00087 | 11,078,403 | D000818:Animals; D001145:Arrhythmias, Cardiac; D019332:Endothelin-1; D008297:Male; D017202:Myocardial Ischemia; D051381:Rats; D017207:Rats, Sprague-Dawley; D044023:Receptor, Endothelin B; D017466:Receptors, Endothelin; D014757:Viper Venoms | Journal of cardiovascular pharmacology | 2,000 | D019332:Endothelin-1; D044023:Receptor, Endothelin B; D017466:Receptors, Endothelin; D014757:Viper Venoms; C057354:sarafotoxins s6 |
[Influence of metallurgy occupational hazards on oral cavity diseases in Far North]. | Clinical studies proved metallurgic production hazards and extreme climate conditions of Far North to influence negatively dental state. | 18,763,610 | D000293:Adolescent; D000328:Adult; D001110:Arctic Regions; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008669:Metallurgy; D008875:Middle Aged; D009017:Morbidity; D009059:Mouth Diseases; D009784:Occupational Diseases; D016273:Occupational Exposure; D012426:Russia; D055815:Young Adult | Meditsina truda i promyshlennaia ekologiia | 2,008 | ||
Comparison of in vitro activity of five antifungal agents against dermatophytes, using the agar dilution and broth microdilution methods. | The purpose of this study was to compare the agar dilution and broth microdilution methods for determining the minimum inhibitory concentration (MIC) of fluconazole, itraconazole, ketoconazole, griseofulvin and terbinafine for 60 dermatophyte samples belonging to the species Trichophyton rubrum, Trichophyton mentagroph... | 19,684,970 | D000935:Antifungal Agents; D003883:Arthrodermataceae; D006801:Humans; D021261:Parasitic Sensitivity Tests | Revista da Sociedade Brasileira de Medicina Tropical | 2,009 | D000935:Antifungal Agents | |
CLNR1, the AREA/NIT2-like global nitrogen regulator of the plant fungal pathogen Colletotrichum lindemuthianum is required for the infection cycle. | Nitrogen starvation is generally assumed to be encountered by biotrophic and hemibiotrophic plant fungal pathogens at the beginning of their infection cycle. We tested whether nitrogen starvation constitutes a cue regulating genes that are required for pathogenicity of Colletotrichum lindemuthianum, a fungal pathogen o... | 10.1046/j.1365-2958.2003.03451.x | 12,694,611 | D000595:Amino Acid Sequence; D001233:Aspergillus nidulans; D020231:Colletotrichum; D007887:Fabaceae; D005656:Fungal Proteins; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D008969:Molecular Sequence Data; D009154:Mutation; D009584:Nitrogen; D009586:Nitrogen Fixation; D016415:Sequence Alignment; D01... | Molecular microbiology | 2,003 | C079728:AreA protein, Aspergillus nidulans; D005656:Fungal Proteins; D014157:Transcription Factors; D009584:Nitrogen |
Efficacy of rituximab in thymoma associated minimal change disease: case report. | BACKGROUND
Thymomas have been associated with a broad spectrum of autoimmune diseases. Minimal change disease (MCD) is the most frequent pathological lesion reported. Pathophysiological mechanisms involved in secondary MCD, and linking MCD to thymoma are not yet fully explained, although the hypothesis of T cell dysfun... | 10.1186/s12882-021-02479-8 | 34,493,204 | D004351:Drug Resistance; D005260:Female; D006801:Humans; D007155:Immunologic Factors; D007668:Kidney; D008875:Middle Aged; D009402:Nephrosis, Lipoid; D009404:Nephrotic Syndrome; D000069283:Rituximab; D013934:Thymectomy; D013945:Thymoma; D013953:Thymus Neoplasms | BMC nephrology | 2,021 | D007155:Immunologic Factors; D000069283:Rituximab |
The use of small-bore wire-guided chest drains for the management of feline pyothorax: A retrospective case series. | Background
Pyothorax in cats is routinely managed, at least initially, with thoracic tube placement associated with systemic antimicrobial administration. Traditionally, large-bore trocar-type thoracostomy tubes have preferentially been used for the drainage of thick material from the pleural space. In recent years, th... | 10.4314/ovj.v10i4.12 | 33,614,440 | D000818:Animals; D002371:Cat Diseases; D002415:Cats; D015505:Chest Tubes; D016724:Empyema, Pleural; D005260:Female; D008297:Male; D011183:Postoperative Complications; D012189:Retrospective Studies; D013907:Thoracostomy | Open veterinary journal | 2,021 | |
Canada's first case of a multidrug-resistant Corynebacterium diphtheriae strain, isolated from a skin abscess. | A toxigenic Corynebacterium diphtheriae biovar mitis sequence type 136 (ST136) strain was recovered from a toe infection of an unvaccinated patient recently returned from India. The isolate was resistant to clindamycin, erythromycin (ermX positive), tetracycline, and trimethoprim-sulfamethoxazole, intermediate to ceftr... | 10.1128/JCM.05296-11 | 21,880,960 | D000038:Abscess; D000328:Adult; D000900:Anti-Bacterial Agents; D015373:Bacterial Typing Techniques; D002170:Canada; D003353:Corynebacterium diphtheriae; D004165:Diphtheria; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D007194:India; D008297:Male; D058889:Molecular Typing; D017192:Skin Diseases, Bacteri... | Journal of clinical microbiology | 2,011 | D000900:Anti-Bacterial Agents |
Effects of pravastatin, a new HMG-CoA reductase inhibitor, on vitamin D synthesis in man. | The HMG-CoA reductase inhibitors, a new class of lipid-lowering agents being used with increasing frequency, inhibit synthesis of cholesterol in vivo. Thus, one potential side effect of these drugs is alteration of other metabolic pathways requiring intermediates in the cholesterol biosynthetic pathway. We hypothesized... | 10.1016/0026-0495(91)90235-o | 1,902,546 | D000328:Adult; D005260:Female; D006538:Heptanoic Acids; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008297:Male; D008903:Minerals; D009281:Naphthalenes; D017035:Pravastatin; D014466:Ultraviolet Rays; D014807:Vitamin D | Metabolism: clinical and experimental | 1,991 | D006538:Heptanoic Acids; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008903:Minerals; D009281:Naphthalenes; D014807:Vitamin D; D017035:Pravastatin |
An integrated widefield imaging and spectroscopy system for contrast-enhanced, image-guided resection of tumors. | UNLABELLED
Tumor recurrence following surgery is a common and unresolved medical problem of great importance since surgery is the most widely used treatment for solid-mass tumors worldwide. A contributing factor to tumor recurrence is the presence of residual tumor remaining at or near the surgical site following surge... | 10.1109/TBME.2015.2389626 | 25,585,410 | D000818:Animals; D045744:Cell Line, Tumor; D004285:Dogs; D005260:Female; D007208:Indocyanine Green; D051379:Mice; D008819:Mice, Nude; D009369:Neoplasms; D061848:Optical Imaging; D025321:Surgery, Computer-Assisted | IEEE transactions on bio-medical engineering | 2,015 | D007208:Indocyanine Green |
Invasion threshold in heterogeneous metapopulation networks. | We study the dynamics of epidemic and reaction-diffusion processes in metapopulation models with heterogeneous connectivity patterns. In susceptible-infected-removed-like processes, along with the standard local epidemic threshold, the system exhibits a global invasion threshold. We provide an explicit expression of th... | 10.1103/PhysRevLett.99.148701 | 17,930,732 | D000818:Animals; D003141:Communicable Diseases; D004196:Disease Outbreaks; D006801:Humans; D008954:Models, Biological; D011157:Population Dynamics; D014195:Travel | Physical review letters | 2,007 | |
Overview of magnetic resonance imaging for management of relapsing-remitting multiple sclerosis in everyday practice. | Although the value of magnetic resonance imaging (MRI) for diagnosis/differential diagnosis of patients with clinically isolated syndromes suggestive of multiple sclerosis (MS) is widely accepted, adoption of MRI into clinical practice to monitor disease evolution remains a work in progress. However, an accumulating bo... | 10.1111/ene.12800 | 26,374,510 | D018450:Disease Progression; D006801:Humans; D008279:Magnetic Resonance Imaging; D020529:Multiple Sclerosis, Relapsing-Remitting; D017063:Outcome Assessment, Health Care | European journal of neurology | 2,015 | |
Loss of Financial Management Independence After Brain Injury: Survivors' Experiences. | OBJECTIVE
This pilot study explored the experiences of brain injury survivors after a change in financial management (FM) independence.
METHOD
Using a qualitative descriptive design, 6 participants with acquired brain injury were recruited from a community brain injury organization and participated in semistructured ... | 10.5014/ajot.2016.020198 | 27,089,291 | D000328:Adult; D001930:Brain Injuries; D005190:Family; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D008016:Life Change Events; D008297:Male; D009788:Occupational Therapy; D036301:Qualitative Research; D012944:Social Support; D017741:Survivors | The American journal of occupational therapy : official publication of the American Occupational Therapy Association | 2,016 | |
Body Mass Index, Genetic Susceptibility, and Risk of Complications Among Individuals with Crohn's Disease. | BACKGROUND
Obesity is associated with systemic and intestine-specific inflammation and alterations in gut microbiota, which in turn impact mucosal immunity. Nonetheless, a specific role of obesity and its interaction with genetics in the progression of Crohn's disease (CD) is unclear.
METHODS
We conducted a cross-sec... | 10.1097/MIB.0000000000000498 | 26,181,430 | D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D015992:Body Mass Index; D003251:Constriction, Pathologic; D003424:Crohn Disease; D003430:Cross-Sectional Studies; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009765:Obesi... | Inflammatory bowel diseases | 2,015 | |
Stability of lutein in O/W emulsion prepared using xanthan and propylene glycol alginate. | Lutein is a hydrophobic carotenoid with diverse bioactivities. For encapsulating the molecule in a novel method, we prepared two emulsions from xanthan and propylene glycol alginate at the ratios of 3:7 and 4:6. The instability index and particle size of the emulsions were determined using a stability analyzer and lase... | 10.1016/j.ijbiomac.2020.02.162 | 32,084,481 | D000464:Alginates; D004355:Drug Stability; D045703:Emulsifying Agents; D004655:Emulsions; D014975:Lutein; D010316:Particle Size; D011135:Polysaccharides, Bacterial; D014783:Viscosity | International journal of biological macromolecules | 2,020 | D000464:Alginates; D045703:Emulsifying Agents; D004655:Emulsions; D011135:Polysaccharides, Bacterial; C038550:propylene glycol alginate ester; C002563:xanthan gum; D014975:Lutein |
Challenges of Setting up a Lower Extremity Reconstruction Practice in a Constrained Environment. | BACKGROUND
Microsurgical lower extremity reconstruction remains challenging, especially when resources are limited such as lack of proper equipment, human resources, administrative support, and located in a remote area far from tertiary care. Nevertheless, reconstructive solutions are required, especially when in urgen... | 10.1055/s-0039-1701041 | 31,994,159 | D005260:Female; D006801:Humans; D007083:Iliac Artery; D035002:Lower Extremity; D008297:Male; D061525:Perforator Flap; D019651:Plastic Surgery Procedures; D016896:Treatment Outcome | Journal of reconstructive microsurgery | 2,021 | |
Is ADHD a risk factor independent of conduct disorder for illicit substance use? A meta-analysis and metaregression investigation. | OBJECTIVE
To investigate meta-analytically if the association between ADHD and illicit substance use (ISU) is maintained when controlling for conduct disorder/oppositional-defiant disorder (CD/ODD).
METHOD
A systematic literature review was conducted through Medline from 1980 to 2008. Data extracted and selections ma... | 10.1177/1087054711435362 | 22,344,318 | D001289:Attention Deficit Disorder with Hyperactivity; D015897:Comorbidity; D019955:Conduct Disorder; D006801:Humans; D016017:Odds Ratio; D012044:Regression Analysis; D012307:Risk Factors; D019966:Substance-Related Disorders | Journal of attention disorders | 2,013 | |
Identification of Flk-1 target genes in vasculogenesis: Pim-1 is required for endothelial and mural cell differentiation in vitro. | The tyrosine kinase receptor fetal liver kinase 1 (Flk-1) plays a crucial role in vasculogenesis and angiogenesis, but its target genes remain elusive. Comparing Flk-1(+/+) with Flk-1(-/-) embryonic stem (ES) cells, we identified transcripts regulated by the vascular endothelial growth factor A (VEGF-A)/Flk-1 pathway a... | 10.1182/blood-2003-11-3827 | 14,982,870 | D000818:Animals; D001483:Base Sequence; D002454:Cell Differentiation; D002478:Cells, Cultured; D017931:DNA Primers; D004730:Endothelium, Vascular; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D066298:In Vitro Techniques; D051379:Mice; D018345:Mice, Knockout; D009131:Muscle, Smooth,... | Blood | 2,004 | D017931:DNA Primers; D011518:Proto-Oncogene Proteins; D034741:RNA, Small Interfering; D040281:Vascular Endothelial Growth Factor Receptor-1; C496634:PIM1 protein, human; C496636:Pim1 protein, mouse; D017346:Protein Serine-Threonine Kinases; D051573:Proto-Oncogene Proteins c-pim-1 |
More than the sum of its parts? A qualitative research synthesis on multi-disciplinary primary care teams. | This qualitative research synthesis reviews interpretive scholarly papers on multi-disciplinary primary care teams. A bibliographic search was conducted in electronic databases: Medline, Embase, and the Web of Science Citation Index, and in the references of retrieved papers. The research consists of a taxonomic analys... | 10.1080/13561820802380035 | 19,012,139 | D006801:Humans; D033183:Interdisciplinary Communication; D010348:Patient Care Team; D011320:Primary Health Care; D036301:Qualitative Research | Journal of interprofessional care | 2,008 | |
Bilateral Candidal abscess of the parotid gland: A case report and literature review. | We report the case of a 75-year-old diabetic man who developed a bilateral abscess of the parotid gland. Although a bacterial parotitis was first suspected, cultures of fine-needle aspiration identified Candida albicans as the causal agent. Failure of medical treatment led us to perform a surgical drainage of the right... | 10.1016/j.jormas.2022.101355 | 36,513,275 | D008297:Male; D006801:Humans; D000368:Aged; D010306:Parotid Gland; D000038:Abscess; D010309:Parotitis | Journal of stomatology, oral and maxillofacial surgery | 2,023 | |
Resilience Analysis of a Remote Offshore Oil and Gas Facility for a Potential Hydrocarbon Release. | Resilience is the capability of a system to adjust its functionality during a disturbance or perturbation. The present work attempts to quantify resilience as a function of reliability, vulnerability, and maintainability. The approach assesses proactive and reactive defense mechanisms along with operational factors to ... | 10.1111/risa.12974 | 29,446,108 | Risk analysis : an official publication of the Society for Risk Analysis | 2,018 | ||
Solitary calix in siblings. | An unusual anomaly of a solitary kidney with a solitary calix in siblings is described. | 10.1016/s0022-5347(17)56558-1 | 501,828 | D000293:Adolescent; D005260:Female; D006801:Humans; D007668:Kidney; D007670:Kidney Calices; D007682:Kidney Pelvis; D008297:Male; D011859:Radiography | The Journal of urology | 1,979 | |
Common methionine-tryptic peptides near the amino-terminal end of primate papovavirus tumor antigens. | The tumor antigens directed by human papovaviruses BK and JC and the monkey papovavirus simian virus 40 have two methionine-containing tryptic peptides in common. These peptides are constituents of the small forms of papovavirus tumor antigen (17,000 daltons) which are present in lytically infected and transformed cell... | 10.1073/pnas.75.3.1131 | 206,886 | D000595:Amino Acid Sequence; D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D001739:BK Virus; D005814:Genes, Viral; D008970:Molecular Weight; D027383:Papillomaviridae; D010446:Peptide Fragments; D027382:Polyomaviridae; D013539:Simian virus 40; D014764:Viral Proteins | Proceedings of the National Academy of Sciences of the United States of America | 1,978 | D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D010446:Peptide Fragments; D014764:Viral Proteins |
Self-reported health status, health vulnerability, and smoking behavior in college students: implications for intervention. | Health-related factors, including prevalence of respiratory symptoms and perceived health status, were analyzed by smoking status and by stages of change for quitting to evaluate their potential use as motivators for tobacco cessation. Data were obtained from a survey of 1,283 Houston-area community college students. R... | 10.1080/1462220031000118649 | 12,959,792 | D000293:Adolescent; D000328:Adult; D003376:Counseling; D005260:Female; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D008297:Male; D009042:Motivation; D012140:Respiratory Tract Diseases; D012907:Smoking; D016540:Smoking Cessation; D013334:Students; D014342:Truth Disclosure | Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco | 2,003 | |
[Air pollutant burden and bronchial asthma in school children]. | To examine the possibility of an effect of indoor and outdoor exposures on the prevalence of asthma in childhood we conducted a cross-sectional study in the area of Freiburg city and two communities in the Black Forest. The study group consists of 704 children aged 7 to 16 years. The children and their mothers took par... | 10.1007/BF01846044 | 1,867,012 | D000293:Adolescent; D000393:Air Pollutants; D001249:Asthma; D002648:Child; D015986:Confounding Factors, Epidemiologic; D003430:Cross-Sectional Studies; D005260:Female; D005858:Germany; D006361:Heating; D006801:Humans; D016015:Logistic Models; D008297:Male; D009585:Nitrogen Dioxide; D016017:Odds Ratio | Sozial- und Praventivmedizin | 1,991 | D000393:Air Pollutants; D009585:Nitrogen Dioxide |
Robustness of central carbohydrate metabolism in developing maize kernels. | The central carbohydrate metabolism provides the precursors for the syntheses of various storage products in seeds. While the underlying biochemical map is well established, little is known about the organization and flexibility of carbohydrate metabolic fluxes in the face of changing biosynthetic demands or other pert... | 10.1016/j.phytochem.2006.05.035 | 16,815,503 | D050260:Carbohydrate Metabolism; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D003313:Zea mays | Phytochemistry | 2,006 | |
Structural and functional analyses of PpENA1 provide insights into cation binding by type IID P-type ATPases in lower plants and fungi. | PpENA1 is a membrane-spanning transporter from the moss Physcomitrella patens, and is the first type IID P-type ATPase to be reported in the plant kingdom. In Physcomitrella, PpENA1 is essential for normal growth under moderate salt stress, while in yeast, type IID ATPases provide a vital efflux mechanism for cells und... | 10.1016/j.bbamem.2010.11.013 | 21,081,109 | D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D001665:Binding Sites; D019068:Bryopsida; D002412:Cations; D005656:Fungal Proteins; D005658:Fungi; D005816:Genetic Complementation Test; D015151:Immunoblotting; D017136:Ion Transport; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009154:Mutati... | Biochimica et biophysica acta | 2,011 | D002412:Cations; D005656:Fungal Proteins; D010940:Plant Proteins; C559659:PpENA1 protein, Physcomitrella patens; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium |
National surveillance of dialysis associated diseases in the United States, 1995. | Chronic hemodialysis centers in the United States were surveyed in 1995 regarding a number of hemodialysis associated diseases and practices. A total of 2,647 centers, representing 224,954 patients and 54,194 staff members, responded. Seventy-seven percent of centers reported that they reused disposable dialyzers. At t... | 10.1097/00002480-199801000-00019 | 9,466,509 | D001166:Arteriovenous Shunt, Surgical; D002408:Catheters, Indwelling; D017743:Equipment Reuse; D015658:HIV Infections; D006509:Hepatitis B; D006526:Hepatitis C; D006801:Humans; D015994:Incidence; D011159:Population Surveillance; D006435:Renal Dialysis; D013203:Staphylococcal Infections; D011795:Surveys and Questionnair... | ASAIO journal (American Society for Artificial Internal Organs : 1992) | 1,998 | |
Describing patients' needs in the context of research priorities in patients with multiple myeloma or Waldenstrom's disease: A truly patient-driven study. | BACKGROUND
To ensure true patient-centered care, the urgency of patient participation in research is increasingly recognized. This study takes this one step further and reports on patient participation in describing patients' needs for improving quality of care in the context of research priorities - a challenging part... | 27,172,780 | D035843:Biomedical Research; D005858:Germany; D006801:Humans; D009101:Multiple Myeloma; D020380:Needs Assessment; D009426:Netherlands; D010358:Patient Participation; D011795:Surveys and Questionnaires; D008258:Waldenstrom Macroglobulinemia | Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen | 2,016 |
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