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Burden and outcome of HIV infection and other morbidities in health care workers attending an Occupational Health Program at the Provincial Hospital of Tete, Mozambique. | OBJECTIVES
To investigate the burden and outcome of HIV infection and other morbidities amongst a Mozambican hospital staff.
METHODS
Within an occupational health service set up in April 2008 in the provincial hospital of Tete, Mozambique, we offered to all staff members an initial clinical, laboratory and radiologic... | 10.1111/j.1365-3156.2011.02853.x | 21,848,576 | D000328:Adult; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections; D006282:Health Personnel; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional; D017757:Infectious Disease Transmission, Professional-to-Patient; D008137:Longitudinal Studies; D008297:Male; D008403:Mass Screening;... | Tropical medicine & international health : TM & IH | 2,011 | |
Transcriptome analysis of xa5-mediated resistance to bacterial leaf streak in rice (Oryza sativa L.). | Bacterial leaf steak (BLS) caused by Xanthomonas oryzae pv. oryzicola (Xoc) is a devastating disease in rice production. The resistance to BLS in rice is a quantitatively inherited trait, of which the molecular mechanism is still unclear. It has been proved that xa5, a recessive bacterial blast resistance gene, is the ... | 10.1038/s41598-020-74515-w | 33,173,096 | D060467:Disease Resistance; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D012275:Oryza; D030821:Plants, Genetically Modified; D034622:RNA Interference; D017423:Sequence Analysis, RNA; D014974:Xanthomonas | Scientific reports | 2,020 | |
The effect of soil pH and temperature on Folsomia candida transcriptional regulation. | Differences in abiotic factors like temperature and soil pH can have a significant physiological impact on soil dwelling invertebrates and may confound results in ecotoxicological testing. In this study we exposed Folsomia candida to a range of two abiotic stress treatments (pH and temperature) for 3 days and measured ... | 10.1016/j.jinsphys.2009.11.004 | 19,931,278 | D000818:Animals; D005786:Gene Expression Regulation; D006863:Hydrogen-Ion Concentration; D019476:Insect Proteins; D007313:Insecta; D008969:Molecular Sequence Data; D012987:Soil; D013696:Temperature; D014158:Transcription, Genetic | Journal of insect physiology | 2,010 | D019476:Insect Proteins; D012987:Soil |
Crystallization of the Fab fragments of anti-peptide monoclonal antibodies and a complex with peptide. | The antigen-binding fragments of four monoclonal antibodies that cross-react with both the "loop" peptide of hen egg-white lysozyme (residues 57 to 84) against which they were raised, and with the native protein (HEL) have been crystallized. One of these fragments also crystallizes as a complex with the peptide antigen... | 10.1016/0022-2836(92)90740-b | 1,731,084 | D000818:Animals; D000911:Antibodies, Monoclonal; D003461:Crystallography; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D046911:Macromolecular Substances; D051379:Mice; D009113:Muramidase; D010455:Peptides | Journal of molecular biology | 1,992 | D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D046911:Macromolecular Substances; D010455:Peptides; D009113:Muramidase |
Cosmetic analysis following breast-conserving surgery and adjuvant high-dose-rate interstitial brachytherapy for early-stage breast cancer: a prospective clinical study. | PURPOSE
To prospectively evaluate cosmetic outcomes in women treated with accelerated partial breast irradiation using high-dose-rate interstitial brachytherapy for early-stage breast cancer.
METHODS AND MATERIALS
Between 2004 and 2008, 151 patients with early-stage breast cancer were enrolled in a phase 2 prospectiv... | 23,058,060 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D001940:Breast; D001941:Breast Diseases; D001943:Breast Neoplasms; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007239:Infections; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009367:Neoplasm Staging; D009929:Orga... | International journal of radiation oncology, biology, physics | 2,013 | ||
The current availability of antiepileptic drugs in Zambia: implications for the ILAE/WHO "out of the shadows" campaign. | Recent concerns regarding antiepileptic drug (AED) availability in Zambia led us to conduct a study in the Lusaka and Southern Provinces to quantify the availability and cost of AEDs and assess determinants. Among 111 pharmacies, almost one-half did not carry AEDs (N = 54; 49.1%). Available AEDs were phenobarbitone (21... | 10.4269/ajtmh.2010.10-0100 | 20,810,822 | D000927:Anticonvulsants; D016527:Drug Costs; D004827:Epilepsy; D006297:Health Services Accessibility; D006801:Humans; D015024:Zambia | The American journal of tropical medicine and hygiene | 2,010 | D000927:Anticonvulsants |
Rome III subgroups of functional dyspepsia exhibit different characteristics of antral contractions measured by strain rate imaging - a pilot study. | PURPOSE
Rome III defines two distinct entities of functional dyspepsia (FD), namely epigastric pain syndrome (EPS) and postprandial distress syndrome (PDS). We aimed at studying these subgroups of FD by simultaneously assessing antral strain, gastric accommodation and emptying and visceral hypersensitivity.
MATERIALS... | 10.1055/s-0032-1313073 | 23,247,728 | D015746:Abdominal Pain; D000328:Adult; D004415:Dyspepsia; D005215:Fasting; D005260:Female; D005746:Gastric Emptying; D005767:Gastrointestinal Diseases; D006801:Humans; D007089:Image Enhancement; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008875:Middle Aged; D010528:Peristalsis; D010865:Pilot Projec... | Ultraschall in der Medizin (Stuttgart, Germany : 1980) | 2,012 | |
[Demography and the phenomenon of intraspecific competition of Gymnophallidae Morozov, 1955 in the second intermediate hosts (Trematoda, Digenea)]. | In Gymnophallidae life-cycle, the primary host is very often a Lamelli-branch, rarely a Prosobranch; the second intermediate host is usually a Pelecypod, rarely a Prosobranch or an Annelid. The first host is generally sedentary; consequently, cercariae are not widely spread. The second intermediate host cannot explore ... | 7,258,994 | D000818:Animals; D002453:Cell Cycle; D005602:France; D006790:Host-Parasite Interactions; D008974:Mollusca; D011077:Polychaeta; D014200:Trematoda | Annales de parasitologie humaine et comparee | 1,981 | ||
Injection drug use-related HIV healthcare--problems and management in Edinburgh. | The relatively high numbers of patients with IDU-related HIV in Scotland has resulted in considerable management difficulties not previously experienced by other medical units. Chronic physical ill health in drug users is becoming commoner with the advent of HIV and other centres are now experiencing the type of proble... | 10.1177/095646249500600309 | 7,647,122 | D003617:Dangerous Behavior; D005260:Female; D015658:HIV Infections; D006301:Health Services Needs and Demand; D006801:Humans; D008297:Male; D017751:Safety Management; D012606:Scotland; D015819:Substance Abuse, Intravenous | International journal of STD & AIDS | 1,995 | |
The effect of the American Heart Association step one diet on hyperlipidemia following renal transplantation. | Cardiovascular disease is a frequent cause of morbidity and mortality following renal transplantation. The percentage of deaths due to ischemic cardiovascular disease and cerebrovascular accidents nearly equals that caused by infection among patients receiving their first transplant, according to data from the European... | 10.1097/00007890-199001000-00013 | 2,301,029 | D000328:Adult; D000368:Aged; D001835:Body Weight; D008078:Cholesterol, LDL; D004041:Dietary Fats; D005260:Female; D006801:Humans; D006949:Hyperlipidemias; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012307:Risk Factors | Transplantation | 1,990 | D008078:Cholesterol, LDL; D004041:Dietary Fats |
Effects of a multifaceted psychiatric intervention targeted for the complex medically ill: a randomized controlled trial. | BACKGROUND
This study evaluated a multifaceted psychiatric intervention targeted at the complex medically ill identified by means of the INTERMED, an instrument to assess case complexity.
METHODS
Of 885 rheumatology inpatients and diabetes outpatients who were assessed for eligibility, 247 were identified as complex ... | 10.1159/000129658 | 18,443,391 | D000328:Adult; D001172:Arthritis, Rheumatoid; D003131:Combined Modality Therapy; D015897:Comorbidity; D003863:Depression; D003865:Depressive Disorder, Major; D003922:Diabetes Mellitus, Type 1; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D... | Psychotherapy and psychosomatics | 2,008 | |
Safety evaluation of a sinus surfactant in an explant-based cytotoxicity assay. | OBJECTIVES/HYPOTHESIS
Biofilms are associated with clinical relapse following surgery for chronic rhinosinusitis. Encased bacteria are protected from innate immunity and antimicrobial therapy. Surfactants can disperse the biofilm into its planktonic phenotype so that traditional treatments may be effective. The aim of ... | 10.1002/lary.24255 | 23,780,570 | D018441:Biofilms; D006801:Humans; D066298:In Vitro Techniques; D009297:Nasal Mucosa; D010256:Paranasal Sinuses; D013501:Surface-Active Agents | The Laryngoscope | 2,014 | D013501:Surface-Active Agents |
Effect of hypertriglyceridemia in dyslipidemia-induced impaired glucose tolerance and sex differences in dietary features associated with hypertriglyceridemia among the Japanese population: The Gifu Diabetes Study. | AIMS/INTRODUCTION
The mechanisms underlying hypertriglyceridemia-induced impaired glucose tolerance in Japanese individuals remain unclear. We aimed to evaluate the effect of hypertriglyceridemia on glucose metabolism in comparison with that of increased low-density lipoprotein or decreased high-density lipoprotein lev... | 10.1111/jdi.13398 | 32,894,809 | D000328:Adult; D000368:Aged; D001786:Blood Glucose; D003430:Cross-Sectional Studies; D004032:Diet; D004034:Diet Surveys; D050171:Dyslipidemias; D004435:Eating; D005260:Female; D018149:Glucose Intolerance; D006442:Glycated Hemoglobin; D006801:Humans; D015228:Hypertriglyceridemia; D007333:Insulin Resistance; D007564:Japa... | Journal of diabetes investigation | 2,021 | D001786:Blood Glucose; D006442:Glycated Hemoglobin A; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; C517652:hemoglobin A1c protein, human |
Transrectal biopsy of the prostate and bacteraemia. | Bacteraemia and urinary tract infection are well-recognized complications of urological procedures. This paper compares, for the first time, the incidence of bacteraemia after cystoscopy and transrectal biopsy of the prostate with that following cystoscopy alone. The incidence of bacteraemia in those undergoing biopsy ... | 10.1002/bjs.1800670217 | 7,362,943 | D001706:Biopsy; D003558:Cystoscopy; D006801:Humans; D008297:Male; D011467:Prostate; D011471:Prostatic Neoplasms; D012007:Rectum; D018805:Sepsis; D014552:Urinary Tract Infections | The British journal of surgery | 1,980 | |
Raman effects in the infrared supercontinuum generation in soft-glass PCFs. | Measurements of the Raman gain spectra in the SF6 and SF57 highly-nonlinear-glasses demonstrated twice as high Raman shift in comparison with the fused silica. Numerical simulation predicted that a large Raman shift in combination with high nonlinearity can significantly reduce the required input pulse intensity for su... | 10.1007/s00340-006-2545-y | 20,975,981 | Applied physics. B, Lasers and optics | 2,007 | ||
Molecular insights on xenoestrogenic potential of zearalenone-14-glucoside through a mixed in vitro/in silico approach. | The mycotoxin zearalenone may contaminate food and feed worldwide upon infections by Fusarium spp. of plants and raw materials intended for human and animal consumption. Currently, contamination by zearalenone and congeners pose concern for health due to xenoestrogenic effects. However, while zearalenone and the main r... | 10.1016/j.fct.2017.07.062 | 28,807,876 | D001681:Biological Assay; D001943:Breast Neoplasms; D002470:Cell Survival; D003198:Computer Simulation; D047628:Estrogen Receptor alpha; D004967:Estrogens; D005260:Female; D005504:Food Analysis; D005506:Food Contamination; D020719:Glucuronides; D006801:Humans; D061986:MCF-7 Cells; D008954:Models, Biological; D011485:Pr... | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association | 2,017 | D047628:Estrogen Receptor alpha; D004967:Estrogens; D020719:Glucuronides; C000597750:zearalenone-14-glucuronide; D015025:Zearalenone |
Post COVID Vaccination (COVAXIN™ -BB152 V) Pauci-immune Crescentic Glomerulonephritis. | Coronavirus disease 2019 (COVID-19) pandemic is responsible for widespread morbidity and mortality. The vaccination against the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection, the cause of the COVID-19 pandemic, is currently ongoing across the globe. Rapid vaccination is of paramount importance ... | 10.4103/ijn.ijn_352_21 | 36,568,599 | Indian journal of nephrology | 2,022 | ||
Distinguishing characteristics of exposure to biguanide and sulfonylurea anti-diabetic medications in the United States. | OBJECTIVES
Biguanides and sulfonylureas are anti-hyperglycemic drugs commonly used in the United States. Poisoning with these drugs may lead to serious consequences. The diagnosis of biguanide and sulfonylurea poisoning is based on history, clinical manifestations, and laboratory studies.
METHODS
This study is a six-... | 10.1016/j.ajem.2022.03.023 | 35,398,707 | D015746:Abdominal Pain; D000138:Acidosis; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003404:Creatinine; D003920:Diabetes Mellitus; D003967:Diarrhea; D004244:Dizziness; D006801:Humans; D007003:Hypoglycemia; D007004:Hypoglycemic Agents; D008687:Metformin; D008875:Middle Aged; D009325:Nausea; D012189... | The American journal of emergency medicine | 2,022 | D007004:Hypoglycemic Agents; D013453:Sulfonylurea Compounds; D008687:Metformin; D003404:Creatinine |
Fluorescence in situ detection of human cutaneous melanoma: study of diagnostic parameters of the method. | Multicenter study of the diagnostic parameters was conducted by three groups in Poland to determine if in situ fluorescence detection of human cutaneous melanoma based on digital imaging of spectrally resolved autofluorescence can be used as a tool for a preliminary selection of patients at increased risk of the diseas... | 10.1046/j.0022-202x.2001.01561.x | 11,886,507 | D005820:Genetic Testing; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008545:Melanoma; D009506:Nevus; D011044:Poland; D012878:Skin Neoplasms | The Journal of investigative dermatology | 2,001 | |
Ovarian function after chemotherapy in young breast cancer survivors. | BACKGROUND
As cure rates for breast cancer improve, there is increasing evidence that late effects of treatment-and impaired fertility in particular-are emerging as important concerns among young breast cancer survivors. Older reports have evaluated the occurrence of amenorrhea after treatment, but few data have been r... | 10.3747/co.24.3335 | 29,270,058 | Current oncology (Toronto, Ont.) | 2,017 | ||
Transverse sinus obstruction caused by extradural supra-infratentorial hydatid cyst: A case report and literature review. | Approximately 1-3% of cases of hydatid disease involve the central nervous system (CNS). This study aims to report an extremely rare case of supra-infratentorially located epidural hydatid cyst with transverse venous sinus obstruction which presented with chronic cerebral vein thrombosis (CVT) signs and symptoms. | 10.1002/ccr3.7003 | 36,852,117 | Clinical case reports | 2,023 | ||
Spatiotemporal Alterations in Working Memory-Related Beta Band Neuromagnetic Activity of Patients With Schizophrenia On and Off Antipsychotic Medication: Investigation With MEG. | BACKGROUND AND HYPOTHESIS
We used the uniquely high combined spatial and temporal resolution of magnetoencephalography to characterize working memory (WM)-related modulation of beta band activity in neuroleptic-free patients with schizophrenia in comparison to a large sample of performance-matched healthy controls. We ... | 10.1093/schbul/sbac178 | 36,772,948 | D006801:Humans; D014150:Antipsychotic Agents; D012559:Schizophrenia; D015225:Magnetoencephalography; D008570:Memory, Short-Term; D008279:Magnetic Resonance Imaging; D009483:Neuropsychological Tests; D001931:Brain Mapping | Schizophrenia bulletin | 2,023 | D014150:Antipsychotic Agents |
Reversible splenial lesion after surgery for distant arteriovenous malformation: a case report. | Isolated lesions of the corpus callosum are rare and may represent permanent but also transient responses to various pathology termed "reversible splenial lesion syndrome" (RESLES) when in light of relevant clinical presentation. We present the first case of the RESLES after elective surgery for distant arteriovenous m... | 10.1007/s00701-023-05573-y | 37,055,680 | D006801:Humans; D001165:Arteriovenous Malformations; D001927:Brain Diseases; D003337:Corpus Callosum; D008279:Magnetic Resonance Imaging; D013577:Syndrome | Acta neurochirurgica | 2,023 | |
Barriers to prescribing the Copper T 380A intrauterine device by physicians. | From a questionnaire sent to all obstetricians and gynecologists and all family and general practitioners in San Diego County, California, regarding the Copper T 380A intrauterine device, substantial barriers to prescribing it were identified. Of all physicians responding, 40% reported that they were not recommending t... | 2,219,892 | D001291:Attitude of Health Personnel; D002140:California; D016001:Confidence Intervals; D003300:Copper; D004867:Equipment Design; D005194:Family Practice; D006176:Gynecology; D006801:Humans; D007434:Intrauterine Devices; D009774:Obstetrics; D016017:Odds Ratio; D010820:Physicians; D010818:Practice Patterns, Physicians';... | The Western journal of medicine | 1,990 | D003300:Copper | |
Induction of human herpesvirus 8 gene expression in a posttransplantation primary effusion lymphoma cell line. | Human herpesvirus 8 (HHV-8 or Kaposi's sarcoma herpesvirus) is a gamma herpesvirus that is most likely the etiologic agent of both Kaposi's sarcoma and primary effusion lymphoma (PEL), a rare HIV-associated lymphoma. The role of HHV-8 in post-transplant lymphoma is less well characterized. We demonstrate that HHV-8 is ... | 10.1080/10428190290012173 | 12,002,770 | D015967:Gene Expression Regulation, Viral; D019288:Herpesvirus 8, Human; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation; D016393:Lymphoma, B-Cell; D016066:Pleural Effusion, Malignant; D013755:Tetradecanoylphorbol Acetate; D014407:Tumor Cells, Cultured | Leukemia & lymphoma | 2,002 | D013755:Tetradecanoylphorbol Acetate |
Obstetric, neonatal and anesthetic considerations for preterm labor and delivery. | Preterm birth is a continuing obstetric problem that contributes significantly to the incidence of perinatal death and long-term handicap. In this context, various studies have shown preterm births account for between 69% and 83% of neonatal deaths. Despite this, the incidence of preterm birth has remained static for m... | 12,847,584 | D000773:Anesthesia, Obstetrical; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007752:Obstetric Labor, Premature; D011247:Pregnancy; D012307:Risk Factors; D012529:Saudi Arabia; D015149:Tocolytic Agents | Saudi medical journal | 2,003 | D015149:Tocolytic Agents | |
Picosecond tryptophan fluorescence of thioredoxin: evidence for discrete species in slow exchange. | The steady-state tryptophan fluorescence and time-resolved tryptophan fluorescence of Escherichia coli thioredoxin, calf thymus thioredoxin, and yeast thioredoxin have been studied. In all proteins, the tryptophan residues undergo strong static and dynamic quenching, probably due to charge-transfer interactions with th... | 10.1021/bi00434a038 | 2,663,070 | D000818:Animals; D001426:Bacterial Proteins; D001665:Binding Sites; D002417:Cattle; D004926:Escherichia coli; D005454:Fluorescence Polarization; D007700:Kinetics; D015394:Molecular Structure; D012441:Saccharomyces cerevisiae; D013045:Species Specificity; D013050:Spectrometry, Fluorescence; D013696:Temperature; D013879:... | Biochemistry | 1,989 | D001426:Bacterial Proteins; D013879:Thioredoxins; D014364:Tryptophan |
Chronic ethanol intake in lactating rats: milk analysis. | Milk was analyzed at 5 and 15 days of lactation in rats fed an ethanol liquid diet or appropriate control diet. Alcoholic rats showed blood ethanol levels as high as 43 mM at the end of lactation. Milk from ethanol-fed rats showed an increase in pH, protein and lipids and a decrease in lactose, compared with controls. ... | 10.1016/0742-8413(86)90059-9 | 2,877,774 | D000437:Alcoholism; D000818:Animals; D000431:Ethanol; D005260:Female; D007774:Lactation; D008892:Milk; D011247:Pregnancy; D011248:Pregnancy Complications; D051381:Rats; D011919:Rats, Inbred Strains | Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology | 1,986 | D000431:Ethanol |
Functional magnetic resonance imaging in intact plants--quantitative observation of flow in plant vessels. | Quantitative magnetic resonance (MR) images of flow velocities in intact corn plants were acquired using magnetization-prepared MR microscopy. A phase contrast flow imaging technique was used to quantitate water flow velocities and total volume flow rates in small xylem vessels. The simultaneous measurement of the tran... | 10.1016/s0730-725x(97)00307-x | 9,621,974 | D018527:Hydroponics; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D010944:Plants; D012016:Reference Values; D012212:Rheology; D003313:Zea mays | Magnetic resonance imaging | 1,998 | |
Clinical significance of preserving spontaneous QRS wave in the therapy of DDD pacing for sick sinus syndrome. | The aim of this clinical crossover study was to elucidate the effects of atrioventricular (AV) synchronous pacing on cardiac function in patients with sick sinus syndrome (SSS). Thirty SSS patients, each with dual chamber pacemaker (DDD), were enrolled and divided into two groups based on echocardiographic findings. Gr... | 10.1111/j.1540-8159.2004.00611.x | 15,461,710 | D000368:Aged; D002304:Cardiac Pacing, Artificial; D009202:Cardiomyopathies; D004452:Echocardiography; D018619:Echocardiography, Doppler, Pulsed; D005260:Female; D006349:Heart Valve Diseases; D006801:Humans; D008297:Male; D020097:Natriuretic Peptide, Brain; D012804:Sick Sinus Syndrome | Pacing and clinical electrophysiology : PACE | 2,004 | D020097:Natriuretic Peptide, Brain |
Dissociation of Structural and Functional Integrities of the Motor System in Amyotrophic Lateral Sclerosis and Behavioral-Variant Frontotemporal Dementia. | BACKGROUND AND PURPOSE
This study investigated the structural and functional changes in the motor system in amyotrophic lateral sclerosis (ALS; n=25) and behavioral-variant fronto-temporal dementia (bvFTD; n=17) relative to healthy controls (n=37).
METHODS
Structural changes were examined using a region-of-interest a... | 10.3988/jcn.2016.12.2.209 | 26,932,257 | Journal of clinical neurology (Seoul, Korea) | 2,016 | ||
Management of prolactinoma: a survey of endocrinologists in China. | Objective To assess the current management of prolactinoma among endocrinologists in China. Methods An online survey of a large sample of endocrinologists was conducted in China. The questionnaire included 21 questions related to controversial issues about the management of prolactinomas. Doctors in the endocrinology d... | 30,352,394 | Endocrine connections | 2,018 | |||
Energy and Vibration Absorption Characteristics of Damping Holes under Explosion Dynamic Loading. | There are usually many buildings near the subway. In tunnel construction, the vibration caused by explosion affects the structure of buildings. The vibration and energy absorption characteristics of damping holes caused by tunnel blasting are investigated under explosion dynamic loading, experimentally and numerically.... | 10.1021/acsomega.0c01989 | 32,715,234 | ACS omega | 2,020 | ||
Application of Clavien-Dindo Classification System for Complications of Minimally Invasive Percutaneous Nephrolithotomy. | Objective
To investigate the clinical applications of the Clavien-Dindo classification system (CDCS) in the assessment of perioperative complications in minimally invasive percutaneous nephrolithotomy (MPCNL).
Methods
Totally, 390 patients with renal stones in our hospital from March 2015 to March 2020 were included ... | 10.1155/2021/5361415 | 34,956,571 | D006801:Humans; D007669:Kidney Calculi; D000074642:Nephrolithotomy, Percutaneous; D061646:Operative Time; D011183:Postoperative Complications; D012307:Risk Factors; D016896:Treatment Outcome | Journal of healthcare engineering | 2,021 | |
The grid-blot: a procedure for screening large numbers of monoclonal antibodies for specificity to native and denatured proteins. | This report describes a procedure referred to as a grid-blot for simultaneously testing up to 30 monoclonal antibodies for specificity with an equivalent number of different proteins on a single sheet of nitrocellulose paper. Only 150 microliters of hybridoma culture supernatant is required for the screening and the en... | 10.1089/hyb.1989.8.661 | 2,693,340 | D000818:Animals; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D015153:Blotting, Western; D002352:Carrier Proteins; D004797:Enzyme-Linked Immunosorbent Assay; D007132:Immunoglobulin Isotypes; D007158:Immunologic Techniques; D009124:Muscle Proteins; D011489:Protein Denaturation; D011494:Protein Kinases; ... | Hybridoma | 1,989 | D000911:Antibodies, Monoclonal; D002352:Carrier Proteins; D007132:Immunoglobulin Isotypes; D009124:Muscle Proteins; D011506:Proteins; C079567:myosin-binding protein C; D011494:Protein Kinases |
Two-dimensional fast transforms applied to memory limited disk operating computers. | Two-dimensional transform algorithms are usually impractical to small machines which cannot handle N2 real (or complex) data points in core when N is large. Storing the input data in N disk records and computing two sequential one-dimensional transforms requires N(N + 3) disk access and 2 N applications of the one-dime... | 10.1016/0010-468x(79)90037-0 | 436,408 | D003201:Computers; D005583:Fourier Analysis | Computer programs in biomedicine | 1,979 | |
Evolution of the Bacillus Calmette-Guérin scar Russia and Moreau strains in newborns: A brazilian cohort. | Background
In Brazil, in 1925, the Moreau strain was introduced, and since its implementation, it has been the routine vaccine for health services. Since 2013, many countries, including Brazil, have been experiencing problems with the production of vaccines. As of January 2018, the country started to use the BCG vaccin... | 10.1016/j.jvacx.2023.100323 | 37,333,053 | Vaccine: X | 2,023 | ||
Isolation and crystal structures of two singlet bis(triarylamine) dications with nonquinoidal geometries. | We report the first structural data for bis(diarylamine) "bipolarons": we have isolated and crystallographically characterized salts of the dications obtained by two-electron oxidation of E-4,4'-bis[di(p-anisyl)amino]stilbene and E,E-2,5-bis{4-[di(p-anisyl)amino]styryl}-3,4-di(n-butoxy)thiophene, [1](2+) and [2](2+) re... | 10.1021/ja0541534 | 16,464,079 | D000814:Aniline Compounds; D002412:Cations; D018360:Crystallography, X-Ray; D004578:Electron Spin Resonance Spectroscopy; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013267:Stilbenes | Journal of the American Chemical Society | 2,006 | D000814:Aniline Compounds; D002412:Cations; D013267:Stilbenes |
[Possibilities for the use of exfoliative urine cytology in invasive and noninvasive bladder cancer]. | In invasively growing tumours of the urinary bladder specificity and sensitivity of the urine cytology are sufficiently high with 100 and 66%, respectively, it is, however, not successful. Endoscopy and histological ascertainment are now as ever prevailing (TUR). Cytology is indispensable to the diagnosis of the carcin... | 4,036,385 | D002278:Carcinoma in Situ; D002295:Carcinoma, Transitional Cell; D003131:Combined Modality Therapy; D004848:Epithelium; D006801:Humans; D009367:Neoplasm Staging; D011379:Prognosis; D001743:Urinary Bladder; D001749:Urinary Bladder Neoplasms; D014556:Urine | Zeitschrift fur Urologie und Nephrologie | 1,985 | ||
Abnormalities in lung function following clinical recovery from Mycoplasma pneumoniae pneumonia. | Pulmonary function was studied in 15 patients who had clinically and radiologically recovered from proven Mycoplasma pneumoniae pneumonia, 21 weeks (mean) previously. Ten patients were tested again 43 weeks (mean) later. Lung volumes and measurements of airways resistance were generally normal. Transfer factor and diff... | 7,117,430 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000403:Airway Resistance; D005260:Female; D005540:Forced Expiratory Flow Rates; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D011019:Pneumonia, Mycoplasma; D011653:Pulmonary Diffusing Capacity; D012129:Respiratory Function Tests; ... | European journal of respiratory diseases | 1,982 | ||
Porcelain bond to laser-welded titanium surfaces. | OBJECTIVES
The purpose of this investigation was to determine if laser-welding titanium had an effect on the bond strength of porcelain to metal. This is an important consideration since the metal copings for many multi-unit porcelain restorations are fabricated as single units and then either soldered or welded.
MET... | 10.1016/0109-5641(95)80040-9 | 8,621,040 | D001464:Barium; D001840:Dental Bonding; D003776:Dental Porcelain; D012994:Dental Soldering; D007834:Lasers; D008422:Materials Testing; D016876:Metal Ceramic Alloys; D008855:Microscopy, Electron, Scanning; D014025:Titanium; D014896:Welding | Dental materials : official publication of the Academy of Dental Materials | 1,995 | D016876:Metal Ceramic Alloys; C077451:Procera; D003776:Dental Porcelain; D001464:Barium; D014025:Titanium |
The occurrence and consequences of deoxyuridine in DNA. | Deoxyuridine can become resident in the DNA of prokaryotic and eukaryotic cells via two general mechanisms - deamination of cytosine to uracil, and nucleotide pool changes that lead to misincorporation of deoxyuridine in place of thymidine. In this paper we have examined the chemical basis of deamination reactions in D... | 10.1016/0065-2571(84)90013-x | 6,147,963 | D001482:Base Composition; D002499:Centrifugation, Density Gradient; D002843:Chromatin; D003596:Cytosine; D004247:DNA; D045647:DNA Glycosylases; D043603:DNA-(Apurinic or Apyrimidinic Site) Lyase; D003641:Deamination; D043223:Deoxyribonuclease IV (Phage T4-Induced); D003856:Deoxyuracil Nucleotides; D003857:Deoxyuridine; ... | Advances in enzyme regulation | 1,984 | D002843:Chromatin; D003856:Deoxyuracil Nucleotides; D005493:Folic Acid Antagonists; D011522:Protons; D013938:Thymidine Monophosphate; D003596:Cytosine; D004247:DNA; C007267:2'-deoxyuridylic acid; D004706:Endodeoxyribonucleases; D043223:Deoxyribonuclease IV (Phage T4-Induced); D045647:DNA Glycosylases; D009699:N-Glycosy... |
Effective treatment of established mouse collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express FasL. | Previous reports have demonstrated the ability of antigen-presenting cells (APCs), genetically modified to express Fas ligand (FasL), to inhibit T-cell responses through the induction of apoptosis of antigen-specific T cells. Here we have examined the ability of primary mouse bone marrow-derived dendritic cells (DCs), ... | 12,409,256 | D000818:Animals; D001168:Arthritis; D002455:Cell Division; D003094:Collagen; D016207:Cytokines; D003713:Dendritic Cells; D004195:Disease Models, Animal; D053222:Fas Ligand Protein; D005260:Female; D005434:Flow Cytometry; D015316:Genetic Therapy; D005822:Genetic Vectors; D007371:Interferon-gamma; D008297:Male; D008562:M... | Molecular therapy : the journal of the American Society of Gene Therapy | 2,002 | D016207:Cytokines; D053222:Fas Ligand Protein; C505658:Fasl protein, mouse; D008562:Membrane Glycoproteins; D007371:Interferon-gamma; D003094:Collagen | |
Unrecognized glucose intolerance is common in pulmonary arterial hypertension. | BACKGROUND
Animal and human data suggest insulin resistance is common in pulmonary arterial hypertension (PAH). Although routine assessment of insulin resistance is difficult, hemoglobin A(1c) (HbA(1c)) is a sensitive test to detect diabetes mellitus (DM) and those at high risk for DM. We aimed to define the prevalence... | 10.1016/j.healun.2011.02.016 | 21,493,097 | D000328:Adult; D000368:Aged; D001794:Blood Pressure; D015897:Comorbidity; D005260:Female; D018149:Glucose Intolerance; D006442:Glycated Hemoglobin; D006801:Humans; D006976:Hypertension, Pulmonary; D007333:Insulin Resistance; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:P... | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | 2,011 | D006442:Glycated Hemoglobin A |
Self-reported dependence on mobile phones in young adults: A European cross-cultural empirical survey. | Background and aims Despite many positive benefits, mobile phone use can be associated with harmful and detrimental behaviors. The aim of this study was twofold: to examine (a) cross-cultural patterns of perceived dependence on mobile phones in ten European countries, first, grouped in four different regions (North: Fi... | 10.1556/2006.6.2017.020 | 28,425,777 | D000293:Adolescent; D000328:Adult; D016739:Behavior, Addictive; D040421:Cell Phone; D003431:Cross-Cultural Comparison; D005060:Europe; D006801:Humans; D020407:Internet; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D057566:Self Report; D014495:Universities; D055815:Young Adult | Journal of behavioral addictions | 2,017 | |
Squamous Cell Carcinoma: Restaging and Response to Therapy. | This article describes the use of 18F-fluorodeoxyglucose PET in patients who have head and neck cancer for assessment of therapy response, detection of locoregional recurrence and distant metastasis, and surveillance. | 27,158,108 | PET clinics | 2,007 | |||
Protected areas reduced poverty in Costa Rica and Thailand. | As global efforts to protect ecosystems expand, the socioeconomic impact of protected areas on neighboring human communities continues to be a source of intense debate. The debate persists because previous studies do not directly measure socioeconomic outcomes and do not use appropriate comparison groups to account for... | 10.1073/pnas.0914177107 | 20,498,058 | D044822:Biodiversity; D003247:Conservation of Natural Resources; D003364:Costa Rica; D017753:Ecosystem; D006801:Humans; D018803:Models, Economic; D011203:Poverty; D011204:Poverty Areas; D011640:Public Policy; D013785:Thailand | Proceedings of the National Academy of Sciences of the United States of America | 2,010 | |
Mesenteric panniculitis: systematic review of cross-sectional imaging findings and risk of subsequent malignancy. | OBJECTIVES
Systematic review to determine any association between imaging features of idiopathic mesenteric panniculitis (MP) and subsequent malignancy.
METHODS
Two researchers searched primary literature independently for imaging studies of MP. They extracted data focusing on methodology for unbiased patient accrual... | 10.1007/s00330-016-4298-2 | 27,048,526 | D015982:Bias; D006801:Humans; D015436:Panniculitis, Peritoneal; D010534:Peritoneal Neoplasms; D015995:Prevalence; D012189:Retrospective Studies; D012306:Risk; D014057:Tomography, X-Ray Computed | European radiology | 2,016 | |
Utility of "reposition-flap" in the reconstruction of the avulsed thumb. | Injuries that result in thumb amputation cause a loss of 50% of hand function. Microsurgical replantation remains the gold standard of thumb reconstruction techniques. The non-microsurgical technical variants of thumb reconstruction described so far aim to create a neo-thumb of adequate length, stable, opposable, sensi... | 10.1097/MD.0000000000027290 | 34,559,139 | D000328:Adult; D000368:Aged; D000673:Amputation, Traumatic; D000069836:Degloving Injuries; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012092:Replantation; D012189:Retrospective Studies; D013524:Surgical Flaps; D013933:Thumb | Medicine | 2,021 | |
Hearing Status and Ventilation Tube at Time of Palatoplasty in Cleft Lip and Palate Patients: A Retrospective Study. | Background and Objectives: There is no consensus regarding the indications for and timing of ventilation tube (VT) insertion in cleft lip and palate (CLP) patients. Our aim was to search for clinical and surgical (i.e., VT insertion) characteristics that influence the hearing status in CLP. Materials and Methods: We re... | 10.3390/medicina59030513 | 36,984,514 | D002648:Child; D006801:Humans; D008297:Male; D005260:Female; D000293:Adolescent; D002972:Cleft Palate; D002971:Cleft Lip; D012189:Retrospective Studies; D010034:Otitis Media with Effusion; D034381:Hearing Loss; D021362:Palate, Hard; D006309:Hearing; D003638:Deafness; D016032:Randomized Controlled Trials as Topic | Medicina (Kaunas, Lithuania) | 2,023 | |
Tuberculosis Osteomyelitis as an Indolent Bone Mass. | Tuberculosis (TB) is a pulmonary disease with potential extrapulmonary manifestations that is caused by the bacteria Mycobacterium tuberculosis. Despite advancements in treatment, TB remains a worldwide public health concern. TB osteomyelitis accounts for approximately 3-5% of all extrapulmonary TB cases. We present a ... | 10.7759/cureus.42849 | 37,664,288 | Cureus | 2,023 | ||
Light propagation through a moving gas. | A light beam sufficiently intense to appreciably heat a gas it traverses will be deflected on account of the heat-induced gradients in the index of refraction. We compute these effects (bending into the wind, and self-defocusing due to nonuniformities in the beam) for a nonzero wind velocity in the framework of geometr... | 10.1364/AO.10.001299 | 20,111,109 | Applied optics | 1,971 | ||
Undiscovered Mechanism for Pyrogenic Carbonaceous Matter-Mediated Abiotic Transformation of Azo Dyes by Sulfide. | Pyrogenic carbonaceous matter (PCM) catalyzes the transformation of a range of organic pollutants by sulfide in water; however, the mediation mechanisms are not fully understood. In this study, we observed for the first time that the degradation of azo dyes by sulfide initially underwent a lag phase followed by a fast ... | 10.1021/acs.est.8b06692 | 30,908,036 | D001391:Azo Compounds; D004396:Coloring Agents; D004579:Electron Transport; D010084:Oxidation-Reduction; D011809:Quinones; D013440:Sulfides | Environmental science & technology | 2,019 | D001391:Azo Compounds; D004396:Coloring Agents; D011809:Quinones; D013440:Sulfides |
Maternal care in Mid-Cretaceous lagonomegopid spiders. | Maternal care benefits the survival and fitness of offspring, often at a cost to the mother's future reproduction, and has evolved repeatedly throughout the animal kingdom. In extant spider species, this behaviour is very common and has different levels and diverse forms. However, evidence of maternal care in fossil sp... | 10.1098/rspb.2021.1279 | 34,521,253 | D018647:Amber; D000818:Animals; D005260:Female; D005580:Fossils; D002052:Myanmar; D012098:Reproduction; D013112:Spiders | Proceedings. Biological sciences | 2,021 | D018647:Amber |
Site-Specific N-Glycosylation of Recombinant Pentameric and Hexameric Human IgM. | Glycosylation is known to play an important role in IgG antibody structure and function. Polymeric IgM, the largest known antibody in humans, displays five potential N-glycosylation sites on each heavy chain monomer. IgM can exist as a pentamer with a connecting singly N-glycosylated J-chain (with a total of 51 glycosy... | 10.1007/s13361-016-1378-0 | 27,038,031 | D000595:Amino Acid Sequence; D002853:Chromatography, Liquid; D006020:Glycopeptides; D006031:Glycosylation; D006801:Humans; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011134:Polysaccharides; D053719:Tandem Mass Spectrometry | Journal of the American Society for Mass Spectrometry | 2,016 | D006020:Glycopeptides; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011134:Polysaccharides |
Herpes simplex virus remodels T-cell receptor signaling, resulting in p38-dependent selective synthesis of interleukin-10. | Herpes simplex virus (HSV)-specific T cells are essential for viral clearance. However, T cells do not prevent HSV latent infection or reactivation, suggesting that HSV has the potential to modulate T-cell function. T-cell receptor (TCR) stimulation is a potent and specific means of activating T cells. To investigate h... | 10.1128/JVI.01111-07 | 17,804,501 | D051698:Activating Transcription Factor 2; D002460:Cell Line; D006801:Humans; D016753:Interleukin-10; D048670:MAP Kinase Kinase 4; D035683:MicroRNAs; D010766:Phosphorylation; D011948:Receptors, Antigen, T-Cell; D050796:STAT3 Transcription Factor; D015398:Signal Transduction; D018139:Simplexvirus; D013601:T-Lymphocytes;... | Journal of virology | 2,007 | D051698:Activating Transcription Factor 2; D035683:MicroRNAs; D011948:Receptors, Antigen, T-Cell; D050796:STAT3 Transcription Factor; C494086:STAT3 protein, human; D014764:Viral Proteins; C477253:latency associated transcript, herpes simplex virus-1; D016753:Interleukin-10; D048051:p38 Mitogen-Activated Protein Kinases... |
Acute to chronic pain transition in extremity trauma: A narrative review for future preventive interventions (part 1). | BACKGROUND
Several studies have been conducted over the last decade that describe the issue of pain and prognostic factors of acute to chronic pain transition post extremity trauma (ET). However, no thorough interventions to prevent chronic pain development in ET patients have yet been proposed.
OBJECTIVES
This first... | 10.1016/j.ijotn.2016.04.002 | 27,542,559 | D001134:Arm Injuries; D004638:Emergency Treatment; D005544:Forecasting; D006801:Humans; D007869:Leg Injuries; D059408:Pain Management; D010147:Pain Measurement; D010148:Pain, Intractable | International journal of orthopaedic and trauma nursing | 2,016 | |
The natural history of neoplastic development: the relation of experimental models to human cancer. | The natural history of the development of neoplasia in experimental systems may be separated into at least three different stages, those of initiation, promotion and progression. Evidence for such distinct stages has been demonstrated in at least half a dozen different experimental systems. The stage of promotion is th... | 10.1002/1097-0142(19820315)49:6<1206::aid-cncr2820490623>3.0.co;2-7 | 6,277,460 | D000818:Animals; D002273:Carcinogens; D006528:Carcinoma, Hepatocellular; D006801:Humans; D008099:Liver; D008113:Liver Neoplasms; D051379:Mice; D008954:Models, Biological; D009362:Neoplasm Metastasis; D009369:Neoplasms; D012867:Skin; D013997:Time Factors | Cancer | 1,982 | D002273:Carcinogens |
TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway. | BACKGROUND
Poor cell survival after transplantation restricts the therapeutic potential of mesenchymal stem cell (MSC) transplantation into infarcted hearts, particularly in older individuals. TPP1, a component of the shelterin complex that is involved in telomere protection, is highly expressed in young MSCs but decli... | 10.3389/fcell.2020.588023 | 33,195,247 | Frontiers in cell and developmental biology | 2,020 | ||
Efficacy and safety of becaplermin (recombinant human platelet-derived growth factor-BB) in patients with nonhealing, lower extremity diabetic ulcers: a combined analysis of four randomized studies. | The results of a combined analysis and separate analyses of four multicenter, randomized, parallel group studies that evaluated the effects of once-daily topical administration of becaplermin gel for the treatment of chronic, full thickness, lower extremity diabetic ulcers are presented. The four studies included a tot... | 10.1046/j.1524-475x.1999.00335.x | 10,564,562 | D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000077214:Becaplermin; D005260:Female; D016523:Foot Ulcer; D005782:Gels; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D010982:Platelet-Derived Growth Factor; D020574:Proto-Oncogene Prote... | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society | 1,999 | D005782:Gels; D010982:Platelet-Derived Growth Factor; D020574:Proto-Oncogene Proteins c-sis; D011994:Recombinant Proteins; D000077214:Becaplermin |
[The study on the growth process of ZnO nanorods]. | Albstract The authors synthesized ZnO nanorods by calcining the precursor composed of PVP and Zn(CH3COO)2.2H2O at 300 degrees C. In order to investigate the growth process of ZnO nanorods, the precursor was calcined for different time (0.5, 3, 12, 24 h) and the corresponding products were measured by TEM, HR-TEM (high-... | 16,013,297 | D006358:Hot Temperature; D046529:Microscopy, Electron, Transmission; D036103:Nanotechnology; D043942:Nanotubes; D011205:Povidone; D014961:X-Ray Diffraction; D019345:Zinc Acetate; D015034:Zinc Oxide | Guang pu xue yu guang pu fen xi = Guang pu | 2,005 | D019345:Zinc Acetate; D011205:Povidone; D015034:Zinc Oxide | |
Random-hopping approach to fluctuation phenomena in quantum dots with chiral symmetry. | We propose a numerical approach to study mesoscopic fluctuations in quantum dots with chiral symmetry. Our method involves applying the random-hopping model to a tight-binding Hamiltonian, allowing us to calculate the conductance and shot-noise power distributions for systems belonging to the three chiral symmetry clas... | 10.1063/5.0168974 | 37,934,182 | Chaos (Woodbury, N.Y.) | 2,023 | ||
Randomized, double-blind, multi-center, phase III clinical trial to evaluate the immunogenicity and safety of MG1109 (egg-based pre-pandemic influenza A/H5N1 vaccine) in healthy adults. | Considering the pandemic potential of avian influenza A/H5N1, development of an effective and well-tolerated vaccine is an essential part of pandemic preparedness plans. This phase III, randomized, double-blind study was conducted to assess the immunogenicity and safety profile of an alum-adjuvanted, whole virion, pre-... | 10.1080/21645515.2016.1263410 | 27,996,363 | D000276:Adjuvants, Immunologic; D000293:Adolescent; D000328:Adult; D000536:Aluminum Hydroxide; D000914:Antibodies, Viral; D004311:Double-Blind Method; D005260:Female; D064368:Healthy Volunteers; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D000071497:Immunogenicity, Vaccine; D053124:Influenza A Virus, H5N... | Human vaccines & immunotherapeutics | 2,017 | D000276:Adjuvants, Immunologic; D000914:Antibodies, Viral; D007252:Influenza Vaccines; D000536:Aluminum Hydroxide |
[Progress of molecular biology of CMS in maize]. | In the paper,we have summarized the molecular biological accomplishment acquired and accepted by most of maize researchers on CMS of maize. A brief review of current molecular biological progress of CMS of maize are displayed in the paper. These progresses concern in the positioning,cloning and maker-assisted selection... | 16,135,458 | Yi chuan = Hereditas | 2,002 | |||
MNEMONIC: MetageNomic Experiment Mining to create an OTU Network of Inhabitant Correlations. | BACKGROUND
The number of publicly available metagenomic experiments in various environments has been rapidly growing, empowering the potential to identify similar shifts in species abundance between different experiments. This could be a potentially powerful way to interpret new experiments, by identifying common theme... | 10.1186/s12859-019-2623-x | 30,871,469 | D006801:Humans; D056186:Metagenomics; D064307:Microbiota | BMC bioinformatics | 2,019 | |
Cytokine responses in relation to age, gender, body mass index, Mycobacterium tuberculosis infection, and otitis media among Inuit in Greenland. | OBJECTIVES
To evaluate the cytokine response pattern in Inuit in Greenland in relation to age, gender, body mass index (BMI), Mycobacterium tuberculosis infection (MTI), and otitis media (OM) to assess whether Inuit may have signs of impaired immune responsiveness to infection.
METHODS
A cross-sectional health assess... | 10.1002/ajhb.22332 | 23,073,911 | D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D002648:Child; D003430:Cross-Sectional Studies; D016207:Cytokines; D005260:Female; D006116:Greenland; D006801:Humans; D007371:Interferon-gamma; D016753:Interleukin-10; D004930:Inuit; D016014:Linear ... | American journal of human biology : the official journal of the Human Biology Council | 2,013 | D016207:Cytokines; D010835:Phytohemagglutinins; D013745:Tetanus Toxoid; D014373:Tuberculin; D048069:Tumor Necrosis Factors; D016753:Interleukin-10; D007371:Interferon-gamma |
Precision Oncology Comes of Age: Tumor-Agnostic Approaches. | Colleen Lewis, MSN, ANP-BC, AOCNP®, and R. Donald Harvey, PharmD, BCOP, FCCP, FHOPA, presented on the new world of tumor-agnostic treatment approaches, including those aimed at managing patients with tumors that have high microsatellite instability (MSI-H) or neurotrophic receptor tyrosine kinase (NTRK) fusions. Learn ... | 10.6004/jadpro.2020.11.3.2 | 33,598,315 | Journal of the advanced practitioner in oncology | 2,020 | ||
Acute Kidney Injury Defined by Fluid Corrected Creatinine in Neonates After the Norwood Procedure. | BACKGROUND
Both the Norwood procedure and acute kidney injury (AKI) are associated with significant morbidity and mortality. The impact of AKI by measured and fluid corrected serum creatinine on outcomes after the Norwood procedure has not been previously studied. The purpose of this study was to (1) identify the incid... | 10.1177/2150135118775413 | 30,157,730 | D058186:Acute Kidney Injury; D003120:Colorado; D003404:Creatinine; D005260:Female; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D058327:Norwood Procedures; D016017:Odds Ratio; D012189:Retrospective Studies; D012307:Risk Factors | World journal for pediatric & congenital heart surgery | 2,018 | D003404:Creatinine |
Effects of early pregnancy loss on hormone levels in the subsequent menstrual cycle. | Previous studies of hormone patterns after clinical miscarriage suggest reduced pituitary function. Hormonal effects of very early pregnancy loss (before 6 weeks gestation) have not been described. We used within-woman differences between menstrual cycles in urinary hormone measurements from women in the North Carolina... | 10.3109/09513590.2010.487601 | 20,504,096 | D000022:Abortion, Spontaneous; D000328:Adult; D006063:Chorionic Gonadotropin; D004970:Estrone; D005260:Female; D006801:Humans; D007986:Luteinizing Hormone; D008597:Menstrual Cycle; D011247:Pregnancy; D011276:Pregnanediol; D055815:Young Adult | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology | 2,010 | D006063:Chorionic Gonadotropin; D004970:Estrone; D007986:Luteinizing Hormone; D011276:Pregnanediol |
Human cancer detection and immunotherapy with conjugated and non-conjugated monoclonal antibodies. | Classical therapeutic modalities such as surgery, radiation and chemotherapy not only fail to cure the majority of neoplastic disease, but their employment also leads to severe and debilitating side effects. The severe cancer related morbidity is often associated with the use of radiation and chemotherapy, making them ... | 8,687,112 | D000818:Animals; D018033:Antibodies, Bispecific; D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D002986:Clinical Trials as Topic; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D006825:Hybridomas; D007167:Immunotherapy; D000922:Immunotoxins; D051379:Mice; D009369:Neoplasms; D009857:Oncogen... | Anticancer research | 1,996 | D018033:Antibodies, Bispecific; D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D000922:Immunotoxins | |
[Assessment tools to measure burden in the informal caregiver of patients with dementia]. | UNLABELLED
The complexity of dementia caregiver burden concept has led to a significant number of assessment tests using various approaches. For this reason, a review of these measurementss could be useful for clinical or research purposes.
OBJECTIVE
The objective of the study is to perform an updated review on the t... | 24,161,356 | D000368:Aged; D017028:Caregivers; D017281:Cost of Illness; D003704:Dementia; D006801:Humans; D011795:Surveys and Questionnaires | Revista espanola de geriatria y gerontologia | 2,013 | ||
A large animal model of spinal muscular atrophy and correction of phenotype. | OBJECTIVES
Spinal muscular atrophy (SMA) is caused by reduced levels of survival motor neuron (SMN) protein, which results in motoneuron loss. Therapeutic strategies to increase SMN levels including drug compounds, antisense oligonucleotides, and scAAV9 gene therapy have proved effective in mice. We wished to determine... | 10.1002/ana.24332 | 25,516,063 | D000818:Animals; D015415:Biomarkers; D000229:Dependovirus; D004195:Disease Models, Animal; D004576:Electromyography; D015316:Genetic Therapy; D005822:Genetic Vectors; D006801:Humans; D009046:Motor Neurons; D009134:Muscular Atrophy, Spinal; D010641:Phenotype; D034741:RNA, Small Interfering; D055532:SMN Complex Proteins;... | Annals of neurology | 2,015 | D015415:Biomarkers; D034741:RNA, Small Interfering; D055532:SMN Complex Proteins |
Fibronectin-based scaffold domain proteins that bind myostatin: a patent evaluation of WO2014043344. | Muscular dystrophies (MD) are commonly characterized by progressive loss of muscle mass and function. It is hypothesized that therapeutic blockade of the TGF-β ligand myostatin, a negative regulator of muscle mass, will stimulate muscle growth and restore muscle function. Although many anti-myostatin targets are curren... | 10.1517/13543776.2015.1007954 | 25,632,990 | D000818:Animals; D018450:Disease Progression; D015195:Drug Design; D005353:Fibronectins; D006801:Humans; D058990:Molecular Targeted Therapy; D009135:Muscular Diseases; D009136:Muscular Dystrophies; D055435:Myostatin; D010330:Patents as Topic | Expert opinion on therapeutic patents | 2,015 | D005353:Fibronectins; D055435:Myostatin |
Origin Determination of Walnuts (Juglans regia L.) on a Worldwide and Regional Level by Inductively Coupled Plasma Mass Spectrometry and Chemometrics. | To counteract food fraud, this study aimed at the differentiation of walnuts on a global and regional level using an isotopolomics approach. Thus, the multi-elemental profiles of 237 walnut samples from ten countries and three years of harvest were analyzed with inductively coupled plasma mass spectrometry (ICP-MS), an... | 10.3390/foods9111708 | 33,233,794 | Foods (Basel, Switzerland) | 2,020 | ||
Transmembrane 6 superfamily member 2 167K allele improves renal function in children with obesity. | BACKGROUND
The transmembrane 6 superfamily member 2 (TM6SF2) E167K polymorphism influences estimated glomerular filtration rate (eGFR) in adults without diabetes and without obesity. We aimed exploring the impact of this polymorphism on eGFR in children with obesity with and without non-alcoholic fatty liver disease (N... | 10.1038/s41390-020-0753-5 | 31,923,913 | D000293:Adolescent; D000483:Alleles; D015992:Body Mass Index; D002648:Child; D005260:Female; D020022:Genetic Predisposition to Disease; D005838:Genotype; D005919:Glomerular Filtration Rate; D006720:Homozygote; D006801:Humans; D007668:Kidney; D008049:Lipase; D008297:Male; D008565:Membrane Proteins; D065626:Non-alcoholic... | Pediatric research | 2,020 | D008565:Membrane Proteins; C419195:TM6SF2 protein, human; D008049:Lipase |
Testing biomechanical strength of repairs for the mandibular angle fracture. | A biomechanical model using polystyrene mandibles with simple angle fractures was developed to evaluate the structural strength of a variety of commonly used plate repairs. The model standardized the fracture location, load site, plate location, and site of deformation measurement. The only variables in the study were ... | 10.1288/00005537-199402000-00014 | 8,302,125 | D001696:Biomechanical Phenomena; D001732:Bite Force; D001860:Bone Plates; D005593:Fracture Fixation, Internal; D006801:Humans; D008334:Mandible; D008337:Mandibular Fractures; D008422:Materials Testing; D008961:Models, Structural; D011137:Polystyrenes; D015203:Reproducibility of Results | The Laryngoscope | 1,994 | D011137:Polystyrenes |
Comutagenesis of sodium arsenite with ultraviolet radiation in Chinese hamster V79 cells. | Solar ultraviolet radiation has been associated with the induction of skin cancer. Recent studies have indicated that near-ultraviolet, especially UVB, is mutagenic. Exposure to trivalent inorganic arsenic compounds has also been associated with increased skin cancer prevalence. Trivalent arsenic compounds are not muta... | 10.1007/BF01141180 | 1,777,354 | D000818:Animals; D001151:Arsenic; D018053:Arsenites; D002460:Cell Line; D002470:Cell Survival; D006224:Cricetinae; D004307:Dose-Response Relationship, Radiation; D007041:Hypoxanthine Phosphoribosyltransferase; D016296:Mutagenesis; D017670:Sodium Compounds; D014466:Ultraviolet Rays | Biology of metals | 1,991 | D018053:Arsenites; D017670:Sodium Compounds; C017947:sodium arsenite; D007041:Hypoxanthine Phosphoribosyltransferase; D001151:Arsenic |
Effects of pentoxifylline and metabolite on red blood cell deformability as measured by ektacytometry. | The present investigation sought to evaluate the effects of pentoxifylline and its major hydroxyhexyl metabolite on red blood cell (RBC) deformability using the technique of ektacytometry. Red blood cells were harvested from normal volunteers (normal RBCs) and patients with sickle cell disease (abnormal RBCs) and incub... | 10.1177/000331979004100205 | 2,306,004 | D000755:Anemia, Sickle Cell; D004907:Erythrocyte Deformability; D006801:Humans; D010431:Pentoxifylline; D013805:Theobromine | Angiology | 1,990 | D013805:Theobromine; D010431:Pentoxifylline |
Ureteral replacement with reconfigured colon substitute. | PURPOSE
Upper ureteral defects are often too extensive to repair by direct anastomosis or with use of a bladder flap. Ureteral substitution may be the only remaining alternative to restoring urinary drainage from the kidney to the bladder. This effect is usually achieved by interposing a segment of small bowel between ... | 8,627,855 | D003106:Colon; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D008875:Middle Aged; D011859:Radiography; D015607:Stents; D016896:Treatment Outcome; D014513:Ureter; D014517:Ureteral Obstruction; D014572:Urology | The Journal of urology | 1,996 | ||
Sympathetic overactivity and plasma leptin levels in Rett syndrome. | Rett syndrome (RTT) is a severe developmental-neurological disorder, characterized by profound and progressive loss of intellectual functioning, occurring after a period (of at least 6 months) of normal development with classic stereotype hand movements, gait ataxia, jerky truncal ataxia, deceleration of brain and body... | 10.1016/j.neulet.2007.12.030 | 18,226,448 | D000293:Adolescent; D000328:Adult; D001145:Arrhythmias, Cardiac; D001342:Autonomic Nervous System Diseases; D002648:Child; D002675:Child, Preschool; D005260:Female; D006339:Heart Rate; D006801:Humans; D020738:Leptin; D015518:Rett Syndrome; D014630:Vagus Nerve | Neuroscience letters | 2,008 | D020738:Leptin |
The fluoroquinolones. | The quinolones are broad-spectrum antibacterial agents that have a novel mechanism of action. As synthetic compounds, these agents have been developed extensively to optimize antimicrobial activity, pharmacokinetic properties, and drug safety. Although earlier quinolones were effective only in the genitourinary and gas... | 10.4065/74.10.1030 | 10,918,871 | D000890:Anti-Infective Agents; D001424:Bacterial Infections; D004347:Drug Interactions; D024841:Fluoroquinolones; D006801:Humans | Mayo Clinic proceedings | 1,999 | D000890:Anti-Infective Agents; D024841:Fluoroquinolones |
Steroidogenesis by cultured granulosa cells aspirated from human follicles using pregnenolone and androgens as precursors. | Human granulosa cells from Graafian follicles aspirated 3-4 h before the expected time of ovulation were incubated with various steroid substrates, including pregnenolone, androstenedione, testosterone and dehydroepiandrosterone (DHA). Steroid production after 3 and 10 h of incubation was determined by radioimmunoassay... | 10.1677/joe.0.0770171 | 660,038 | D000728:Androgens; D002478:Cells, Cultured; D006063:Chorionic Gonadotropin; D004958:Estradiol; D005260:Female; D006107:Granulosa Cells; D006801:Humans; D006908:Hydroxyprogesterones; D008596:Menotropins; D011284:Pregnenolone; D011374:Progesterone | The Journal of endocrinology | 1,978 | D000728:Androgens; D006063:Chorionic Gonadotropin; D006908:Hydroxyprogesterones; D011374:Progesterone; D004958:Estradiol; D008596:Menotropins; D011284:Pregnenolone |
Epstein-Barr virus myeloradiculitis and encephalomyeloradiculitis. | We provide a comprehensive clinical, radiological and virological analysis of four patients with Epstein-Barr virus (EBV) infection of the nervous system. One patient developed acute myeloradiculitis, one had acute encephalomyeloradiculitis, one had acute meningoencephalomyeloradiculitis and one had a subacute meningom... | 10.1093/brain/awf010 | 11,834,601 | D000328:Adult; D000914:Antibodies, Viral; D020805:Central Nervous System Viral Diseases; D002555:Cerebrospinal Fluid; D002574:Cervical Vertebrae; D004279:DNA, Viral; D020031:Epstein-Barr Virus Infections; D005260:Female; D004854:Herpesvirus 4, Human; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middl... | Brain : a journal of neurology | 2,002 | D000914:Antibodies, Viral; D004279:DNA, Viral |
Nitrate assimilatory enzymes of Spirulina (Arthospira) platensis are more thermotolerant than those of rice. | In order to assess the potential of Spirulina (Arthospira) platensis as a source of abundant, thermostable nitrate assimilatory enzymes, the specific activities and thermal tolerance of nitrate reductase (NR), nitrite reductase (NiR) and glutamine synthetase (GS) were compared with those of rice in crude extracts in vi... | 10.1007/s12298-009-0031-9 | 23,572,937 | Physiology and molecular biology of plants : an international journal of functional plant biology | 2,009 | ||
Blockade of GPR55 in the dorsolateral striatum impairs performance of rats in a T-maze paradigm. | To investigate the role of GPR55 receptors, which are expressed in human and rat striatum (a structure that regulates procedural memory), Wistar rats received five training sessions (10 trials/session, 1 session/day) to solve a T-maze paradigm. From these data, we constructed learning curves following pharmacological m... | 10.1097/FBP.0000000000000185 | 26,292,188 | D000818:Animals; D053961:Azabicyclo Compounds; D001565:Benzoates; D003071:Cognition; D003342:Corpus Striatum; D005989:Glycerides; D008297:Male; D018782:Maze Learning; D008568:Memory; D010880:Piperidines; D011720:Pyrazoles; D051381:Rats; D017208:Rats, Wistar; D043882:Receptors, Cannabinoid; D043562:Receptors, G-Protein-... | Behavioural pharmacology | 2,016 | C583126:4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid; D053961:Azabicyclo Compounds; D001565:Benzoates; C568825:GPR55 protein, rat; D005989:Glycerides; D010880:Piperidines; D011720:Pyrazoles; D043882:Receptors, Cannabinoid; D043562:Receptors, G-Protein-Coupled; C424... |
[Evaluation of optimal dosage of heparin in hemodialysis patients by thromboelastograph]. | OBJECTIVE
To assess the blood coagulation function and investigate the appropriate dose of unfractionated heparin by thromboelastograph in maintenance hemodialysis (MHD) patients.
METHODS
Thirty MHD patients were enrolled in this study and divided into two groups. The total dose of unfractionated heparin was below 80... | 23,939,176 | D000925:Anticoagulants; D001777:Blood Coagulation; D006493:Heparin; D006801:Humans; D010314:Partial Thromboplastin Time; D006435:Renal Dialysis; D013916:Thrombelastography | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences | 2,013 | D000925:Anticoagulants; D006493:Heparin | |
Analyzing Rural Versus Urban Differences in Career Dissatisfaction and Plans to Leave Among Pennsylvanian Physicians. | PURPOSE
This study estimates whether physicians in rural Pennsylvania have higher odds of career dissatisfaction and plans to leave patient care in the next 6 years, compared to their urban counterparts. Rural-urban differences were estimated across specific subgroups of physicians (gender, race, and specialty) and wit... | 10.1111/jrh.12139 | 26,334,927 | D000328:Adult; D000367:Age Factors; D005260:Female; D006297:Health Services Accessibility; D006280:Health Workforce; D006801:Humans; D007588:Job Satisfaction; D008297:Male; D008511:Medicine; D008875:Middle Aged; D010414:Pennsylvania; D010820:Physicians; D011365:Professional Practice Location; D044469:Racial Groups; D01... | The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association | 2,016 | |
Stereoselective formation of alpha-alkylidene cyclic carbonates via carboxylative cyclization of propargyl alcohols in supercritical carbon dioxide. | Carboxylative cyclization of propargyl alcohols in supercritical carbon dioxide (scCO2) containing P(n-C4H9)3 as a catalyst proceeded smoothly to give alpha-alkylidene-1,3-dioxolan-2-ones. Internal propargyl alcohols afforded Z-alkyl-idene cyclic carbonates exclusively. CO2 incorporation was markedly promoted under sup... | 10.1021/jo062094m | 17,221,989 | The Journal of organic chemistry | 2,007 | ||
DNA sequence of the excision sites of a mitochondrial plasmid from senescent Podospora anserina. | During senescence in Podospora anserina, specific gene regions of the mitochondrial genome are excised and amplified. The most prevalent, termed alpha-event senDNA, is a 2600 bp circular molecule which is excised from the contiguous Hae III fragments 23,14 region of the mitochondrial DNA restriction map. We have cloned... | 10.1093/nar/11.7.2111 | 6,300,793 | D001203:Ascomycota; D001482:Base Composition; D001483:Base Sequence; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D004272:DNA, Mitochondrial; D005784:Gene Amplification; D005796:Genes; D010957:Plasmids; D013098:Xylariales | Nucleic acids research | 1,983 | D004272:DNA, Mitochondrial; D004262:DNA Restriction Enzymes |
A new macrocyclic MRI contrast agent: Gd MCTA complex. | A new macrocyclic complex Gd-MCTA has been synthesized which exhibits a higher LD 50 compared to Gd-DOTA. These two complexes show comparable NMRD profiles. | 10.1002/mrm.1910220215 | 1,812,352 | D003287:Contrast Media; D005682:Gadolinium; D006571:Heterocyclic Compounds; D006801:Humans; D008279:Magnetic Resonance Imaging; D009942:Organometallic Compounds | Magnetic resonance in medicine | 1,991 | D003287:Contrast Media; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C067087:Gd-MCTA; C050823:gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate; D005682:Gadolinium |
Stability of etoposide solutions in disposable infusion devices for day hospital cancer practices. | In a context of day hospital care of cancer patients, a protocol combining etoposide and carboplatin is used in paediatrics. Disposable infusion devices can be used to improve patient quality of life and to optimize nursing time. Stability data are available for carboplatin in these devices but not for etoposide. The a... | 10.1007/s40268-014-0037-9 | 24,627,337 | D000972:Antineoplastic Agents, Phytogenic; D011232:Chemical Precipitation; D002851:Chromatography, High Pressure Liquid; D004209:Disposable Equipment; D004355:Drug Stability; D005047:Etoposide; D007262:Infusions, Intravenous; D009369:Neoplasms | Drugs in R&D | 2,014 | D000972:Antineoplastic Agents, Phytogenic; D005047:Etoposide |
Prevalence of excessive daytime sleepiness in a sample of the Australian adult population. | OBJECTIVES
Excessive daytime sleepiness (EDS) is associated with significant personal and medical burden. However, there is little indication of the impact of these symptoms in the broader population.
PARTICIPANTS AND METHODS
We studied 946 men ages 24-92 years (median age, 59.4 [interquartile range {IQR}, 45-73 year... | 24,513,435 | D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001315:Australia; D006970:Disorders of Excessive Somnolence; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D012959:Socioeconomic Factor... | Sleep medicine | 2,014 | ||
Activation of the hypothalamic paraventricular nucleus by forebrain hypertonicity selectively increases tonic vasomotor sympathetic nerve activity. | We recently reported that mean arterial pressure (MAP) is maintained in water-deprived rats by an irregular tonic component of vasomotor sympathetic nerve activity (SNA) that is driven by neuronal activity in the hypothalamic paraventricular nucleus (PVN). To establish whether generation of tonic SNA requires time-depe... | 10.1152/ajpregu.00460.2014 | 25,519,737 | D000818:Animals; D062186:Arterial Pressure; D017704:Baroreflex; D002319:Cardiovascular System; D003681:Dehydration; D004195:Disease Models, Animal; D018691:Excitatory Amino Acid Antagonists; D058785:GABA-A Receptor Agonists; D006339:Heart Rate; D008297:Male; D064587:Osmoregulation; D010286:Paraventricular Hypothalamic ... | American journal of physiology. Regulatory, integrative and comparative physiology | 2,015 | D018691:Excitatory Amino Acid Antagonists; D058785:GABA-A Receptor Agonists; D011963:Receptors, GABA-A; D016194:Receptors, N-Methyl-D-Aspartate; D012462:Saline Solution, Hypertonic |
Interband scattering in a slow light photonic crystal waveguide under electro-optic tuning. | The evolution of the transmission spectrum of a photonic crystal waveguide under electro-optic tuning was studied in the band of an odd TE-like mode. The spectral signature of the interband scattering from the TM-like mode to the odd TE-like mode was characterized at various bias levels. The shift of the odd-mode band ... | 10.1364/OE.21.006756 | 23,546,058 | D017076:Computer-Aided Design; D003460:Crystallization; D004574:Electromagnetic Fields; D004867:Equipment Design; D019544:Equipment Failure Analysis; D012031:Refractometry; D020349:Surface Plasmon Resonance | Optics express | 2,013 | |
Nasal function and bronchial hyperresponsiveness to methacholine in children. | The objective of the present study was to investigate nasal function by active anterior rhinomanometry with respect to spirometric data and bronchial hyperresponsiveness to methacholine in 9-year-old children. The study population consisted of 300 children (ages 8 to 11 years; mean, 9.3 years; 161 male, 139 female), wh... | 10.1378/chest.107.6.1582 | 7,781,350 | D000403:Airway Resistance; D016535:Bronchial Hyperreactivity; D001985:Bronchial Provocation Tests; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D016210:Methacholine Chloride; D009666:Nose; D012016:Reference Values | Chest | 1,995 | D016210:Methacholine Chloride |
Use of the Orem self-care model on pain relief in women with rheumatoid arthritis: a randomized trial. | BACKGROUND AND AIM
Self-care is an important tool in controlling pain in patients with rheumatoid arthritis. The aim of this study was to determine the use of the Orem self-care model on pain relief in patients with rheumatoid arthritis.
METHODS
This was a clinical trial performed on 60 patients with rheumatoid arthr... | 10.19082/6884 | 30,034,655 | Electronic physician | 2,018 | ||
Trps1 Regulates Development of Craniofacial Skeleton and Is Required for the Initiation of Palatal Shelves Fusion. | Trichorhinophalangeal syndrome (TRPS) is an autosomal dominant disorder resulting from heterozygous mutations of the TRPS1 gene. Common craniofacial abnormalities in TRPS patients include micrognathia, hypoplastic zygomatic arch, high-arched palate, and, occasionally, cleft palate. Studies have demonstrated that mice w... | 10.3389/fphys.2019.00513 | 31,130,868 | Frontiers in physiology | 2,019 | ||
The Influence of Parenting Style and Time Management Tendency on Internet Gaming Disorder among Adolescents. | The problem of adolescent online gaming addiction is related to individual-level characteristics and the influence of the family environment. The present study explores the potential role of adolescents' time management tendency in mediating the relationship between parenting style and adolescent internet gaming disord... | 10.3390/ijerph17239120 | 33,291,336 | D000293:Adolescent; D016739:Behavior, Addictive; D006801:Humans; D020407:Internet; D000082424:Internet Addiction Disorder; D016487:Parenting; D017748:Time Management; D018910:Video Games | International journal of environmental research and public health | 2,020 | |
Two new isoquinoline alkaloids from the seeds of Nandina domestica. | Two new isoquinoline alkaloids, 6 R,6aS-N-nantenine N-oxide (1), 6S,6aS-N-nantenine N-oxide (2), along with nine known alkaloids, nantenine (3), oxonantenine (4), protopine (5), nornantenine (6), N-methyl-laurotetanine (7), isocorydine (8), O-methyflavinantine (9), N-methyl-2,3,6-trimethoxymorphinan-dien-7-one N-oxide ... | 10.1080/14786419.2019.1696334 | 31,872,787 | D000072283:A549 Cells; D000470:Alkaloids; D028141:Berberidaceae; D006801:Humans; D007546:Isoquinolines; D015394:Molecular Structure; D064209:Phytochemicals; D010936:Plant Extracts; D012639:Seeds | Natural product research | 2,021 | D000470:Alkaloids; D007546:Isoquinolines; D064209:Phytochemicals; D010936:Plant Extracts |
Early detection of ventricular dysfunction in juvenile systemic sclerosis by speckle tracking echocardiography. | OBJECTIVE
Cardiac involvement is the most important cause of mortality in juvenile systemic sclerosis (JSSc). Recent reports in adult patients underline that traditional techniques of imaging are inadequate to assess the subclinical cardiac involvement, while speckle tracking echocardiography (STE) is able to identify ... | 10.1093/rheumatology/keaa208 | 32,572,491 | D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D042241:Early Diagnosis; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012595:Scleroderma, Systemic; D018754:Ventricular Dysfunction; D055815:Young Adult | Rheumatology (Oxford, England) | 2,021 |
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