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Laser sculpting of atomic sp, sp(2) , and sp(3) hybrid orbitals.
Atomic sp, sp(2) , and sp(3) hybrid orbitals were introduced by Linus Pauling to explain the nature of the chemical bond. Quantum dynamics simulations show that they can be sculpted by means of a selective series of coherent laser pulses, starting from the 1s orbital of the hydrogen atom. Laser hybridization generates ...
10.1002/cphc.201402588
25,257,703
Chemphyschem : a European journal of chemical physics and physical chemistry
2,015
Contributions of the Ventral Striatum to Conscious Perception: An Intracranial EEG Study of the Attentional Blink.
The brain is limited in its capacity to consciously process information, necessitating gating of information. While conscious perception is robustly associated with sustained, recurrent interactions between widespread cortical regions, subcortical regions, including the striatum, influence cortical activity. Here, we e...
10.1523/JNEUROSCI.2282-16.2016
27,986,925
D000328:Adult; D054518:Attentional Blink; D001479:Basal Ganglia; D003243:Consciousness; D046690:Deep Brain Stimulation; D004569:Electroencephalography; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009434:Neural Pathways; D010465:Perception; D010775:Photic Stimulatio...
The Journal of neuroscience : the official journal of the Society for Neuroscience
2,017
[Synthesis of some 4-nitrophenylfuran derivates analogs of Dantrolene].
Six new phenacylidene derivatives of 5-(4-nitrophenyl)furan were obtained by reacting 5-(nitrophenyl)furfural with 4 substituted acetophenones.
16,092,204
D003620:Dantrolene; D005663:Furans; D009125:Muscle Relaxants, Central; D009578:Nitrobenzenes
Acta poloniae pharmaceutica
1,992
C504500:3-(5-(4-nitrophenyl)furanyl)-1-(4-fluorophenyl)-2-propen-1-one; D005663:Furans; D009125:Muscle Relaxants, Central; D009578:Nitrobenzenes; D003620:Dantrolene
Normal fluctuations in the concentration of corticosteroid and adrenocorticotrophin in the plasma of foetal and pregnant sheep.
Changes in the concentration of adrenocorticotrophin and corticosteroid in the plasma of pregnant and foetal sheep have been followed at different times of day. Wide fluctuations were seen in the concentrations of both in the foetus and ewe, although no evidence for a diurnal rhythm in the ewe was obtained. The foetal ...
10.1055/s-0028-1092716
221,311
D000305:Adrenal Cortex Hormones; D000324:Adrenocorticotropic Hormone; D000818:Animals; D002940:Circadian Rhythm; D005260:Female; D005312:Fetal Blood; D005333:Fetus; D011247:Pregnancy; D011270:Pregnancy, Animal; D012756:Sheep
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
1,979
D000305:Adrenal Cortex Hormones; D000324:Adrenocorticotropic Hormone
Description of the protocol for the PRACTICAL study: a randomised controlled trial of the efficacy and safety of ICS/LABA reliever therapy in asthma.
INTRODUCTION In adult asthma, combination inhaled corticosteroid (ICS)/fast-onset long-acting beta agonist (LABA) used solely as reliever therapy may represent an effective and safe alternative to ICS maintenance and short-acting beta agonist (SABA) reliever therapy. OBJECTIVE To compare the efficacy and safety of IC...
10.1136/bmjresp-2017-000217
29,071,080
BMJ open respiratory research
2,017
Effects of early administration of acetazolamide on the duration of mechanical ventilation in patients with chronic obstructive pulmonary disease or obesity-hypoventilation syndrome with metabolic alkalosis. A randomized trial.
BACKGROUND Metabolic alkalosis (MA) inhibits respiratory drive and may delay weaning from mechanical ventilation (MV). MA is common in CO2-retainer patients that need MV. Acetazolamide (ACTZ) decreases serum bicarbonate concentration and stimulates respiratory drive. This study evaluated the effects of ACTZ on the dura...
10.1016/j.pupt.2017.03.002
28,286,047
D000086:Acetazolamide; D000138:Acidosis; D000368:Aged; D001639:Bicarbonates; D001784:Blood Gas Analysis; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D010845:Obesity Hypoventilation Syndrome; D029424:Pulmonary D...
Pulmonary pharmacology & therapeutics
2,017
D001639:Bicarbonates; D000086:Acetazolamide
Cloned human FMR1 trinucleotide repeats exhibit a length- and orientation-dependent instability suggestive of in vivo lagging strand secondary structure.
The normal human FMR1 gene contains a genetically stable (CGG) n trinucleotide repeat which usually carries interspersed AGG triplets. An increase in repeat number and the loss of interspersions results in array instability, predominantly expansion, leading to FMR1 gene silencing. Instability is directly related to the...
10.1093/nar/26.10.2353
9,580,685
D003001:Cloning, Molecular; D004247:DNA; D004261:DNA Replication; D004926:Escherichia coli; D051860:Fragile X Mental Retardation Protein; D005600:Fragile X Syndrome; D006801:Humans; D008957:Models, Genetic; D009419:Nerve Tissue Proteins; D009690:Nucleic Acid Conformation; D016601:RNA-Binding Proteins; D017422:Sequence ...
Nucleic acids research
1,998
C497683:FMR1 protein, human; D009419:Nerve Tissue Proteins; D016601:RNA-Binding Proteins; D051860:Fragile X Mental Retardation Protein; D004247:DNA
Transferring self-assembled, nanoscale cables into electrical devices.
This study details a new derivative of the contorted HBCs that self-organizes into one-dimensional, single-crystalline fibers. X-ray diffraction, transmission electron microscopy, and electron diffraction studies show that they have an orthorhombic unit cell with dimensions of 5.8 nm x 4.5 nm x 0.45 nm. Each fiber is c...
10.1021/ja0642360
16,910,663
Journal of the American Chemical Society
2,006
[Behavior ethogram and PAE coding system of Cervus nippon sichuanicus].
A monthly 5-day periodic observation at 06:00-18:00 from March to November 2007 was conducted to record the behavioral processes, contents, and results, and the surrounding habitats of Sichuan sika deer (Cervus nippon sichuanicus) in Donglie, Chonger, and Reer villages of Tiebu Natural Reserve of Sichuan Province. The ...
20,462,018
D000818:Animals; D001522:Behavior, Animal; D002681:China; D003247:Conservation of Natural Resources; D003670:Deer; D004777:Environment
Ying yong sheng tai xue bao = The journal of applied ecology
2,010
Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity.
Glycogen and lipids are major storage forms of energy that are tightly regulated by hormones and metabolic signals. We demonstrate that feeding mice a high-fat diet (HFD) increases hepatic glycogen due to increased expression of the glycogenic scaffolding protein PTG/R5. PTG promoter activity was increased and glycogen...
10.2337/db13-1531
24,722,244
D000818:Animals; D059305:Diet, High-Fat; D004734:Energy Metabolism; D005246:Feedback; D006003:Glycogen; D057809:HEK293 Cells; D006801:Humans; D007333:Insulin Resistance; D047908:Intracellular Signaling Peptides and Proteins; D050356:Lipid Metabolism; D050155:Lipogenesis; D008112:Liver Glycogen; D008297:Male; D000076222...
Diabetes
2,014
D047908:Intracellular Signaling Peptides and Proteins; D008112:Liver Glycogen; D046912:Multiprotein Complexes; C104748:Ppp1r3c protein, mouse; D051779:Sterol Regulatory Element Binding Proteins; D006003:Glycogen; D000076222:Mechanistic Target of Rapamycin Complex 1; D058570:TOR Serine-Threonine Kinases
Hemoptysis? Try Inhaled Tranexamic Acid.
BACKGROUND Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent used to prevent and treat various bleeding complications. In many studies, investigators have evaluated its utility and safety orally, intravenously, and topically, but few studies have described the potential benefits of nebulized TXA. CASE REPO...
10.1016/j.jemermed.2018.01.029
29,502,864
D000368:Aged; D000933:Antifibrinolytic Agents; D005260:Female; D006469:Hemoptysis; D006801:Humans; D001239:Inhalation; D009330:Nebulizers and Vaporizers; D014148:Tranexamic Acid
The Journal of emergency medicine
2,018
D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid
Nutrient availability in the Setiu Wetland Lagoon, Malaysia: trends, possible causes and environmental impacts.
The objective of this study was to identify the spatial and temporal variabilities of selected nutrients in the Setiu Wetlands Lagoon (SWL), Malaysia. Water samples were collected quarterly at ten monitoring sites. This study presents results from a 10-year field investigation (2003 to 2010 and 2014 to 2015) of water q...
10.1007/s10661-018-7128-y
30,515,582
D004777:Environment; D004784:Environmental Monitoring; D008296:Malaysia; D000078622:Nutrients; D010758:Phosphorus; D014874:Water Pollutants, Chemical; D060753:Water Quality; D053833:Wetlands
Environmental monitoring and assessment
2,018
D014874:Water Pollutants, Chemical; D010758:Phosphorus
Superior Mesenteric Artery Vasculitis in Behçet's Disease: A Case Report and Literature Review.
A 55-year-old male presented with abdominal pain that had begun about 5 days ago. Physical examination revealed oral aphtha, genital aphthosis, and pseudofolliculitis, and the patient was diagnosed with incomplete Behçet's disease (BD). Contrast-enhanced computed tomography (CECT) showed dilation of the superior mesent...
10.2169/internalmedicine.1290-18
30,146,589
D015746:Abdominal Pain; D000893:Anti-Inflammatory Agents; D001528:Behcet Syndrome; D005938:Glucocorticoids; D006801:Humans; D008297:Male; D017538:Mesenteric Artery, Superior; D008875:Middle Aged; D011239:Prednisolone; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014657:Vasculitis
Internal medicine (Tokyo, Japan)
2,019
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D011239:Prednisolone
The complete chloroplast genome sequence of Styrax odoratissimus (Styracaceae).
Styrax odoratissimus Champ. ex Benth., also known as the extraordinary aromatic plant of Styracaceae, has been seriously threatened due to human activities. In this study, the complete chloroplast (cp) genome sequence of S. odoratissimus was determined by applying next-generation sequencing. The entire cp genome was de...
10.1080/23802359.2019.1688705
33,366,313
Mitochondrial DNA. Part B, Resources
2,019
HLA and HPA typing in idiopathic thrombocytopenic purpura patients treated with Kami-kihi-to.
We performed human leukocyte antigen (HLA) and human platelet antigen (HPA) in patients with Kami-kihi-to-responsive idiopathic thrombocytopenic purpura. The HLA-A2, A61 and Cw1 were significantly increased in responders compared with nonresponders, as were HLA DRB1 *0901, DRB1 *1502, and DPB1 *0501. In contrast, HLA D...
10.1142/S0192415X98000245
9,799,971
D016824:Antigens, Human Platelet; D004365:Drugs, Chinese Herbal; D005260:Female; D006680:HLA Antigens; D015789:HLA-A2 Antigen; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; D006650:Histocompatibility Testing; D006801:Humans; D008297:Male; D016553:Purpura, Thrombocytop...
The American journal of Chinese medicine
1,998
D016824:Antigens, Human Platelet; D004365:Drugs, Chinese Herbal; D006680:HLA Antigens; D015789:HLA-A2 Antigen; D015235:HLA-B Antigens; C079077:HLA-B61 antigen; D015236:HLA-C Antigens; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains
Pharmacological study on Alzheimer's drugs targeting calcium/calmodulin-dependent protein kinase II.
In the brain of Alzheimer's disease patients, down-regulation of both cholinergic and glutamatergic systems have been found and is thought to play an important role in impairment of cognition, learning, and memory. Nefiracetam is a pyrrolidine-related nootropic drug exhibiting various pharmacological actions such as a ...
10.1254/jphs.11r06cp
21,821,968
D000544:Alzheimer Disease; D000818:Animals; D054732:Calcium-Calmodulin-Dependent Protein Kinase Type 2; D004305:Dose-Response Relationship, Drug; D016503:Drug Delivery Systems; D006624:Hippocampus; D017774:Long-Term Potentiation; D009474:Neurons; D018408:Patch-Clamp Techniques; D011760:Pyrrolidinones; D051381:Rats
Journal of pharmacological sciences
2,011
D011760:Pyrrolidinones; C058876:nefiracetam; D054732:Calcium-Calmodulin-Dependent Protein Kinase Type 2
Evaluation of a numerical simulation for cryoablation - comparison with bench data, clinical kidney and lung cases.
PURPOSE The accuracy of a numerical simulation of cryoablation ice balls was evaluated in gel phantom data as well as clinical kidney and lung cases. MATERIALS AND METHODS To evaluate the accuracy, 64 experimental single-needle cryoablations and 12 multi-needle cryoablations in gel phantoms were re-simulated with the...
10.1080/02656736.2020.1845402
33,198,534
D003198:Computer Simulation; D003452:Cryosurgery; D006801:Humans; D007668:Kidney; D008168:Lung; D019047:Phantoms, Imaging
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
2,020
An integrated mediapipe-optimized GRU model for Indian sign language recognition.
Sign language recognition is challenged by problems, such as accurate tracking of hand gestures, occlusion of hands, and high computational cost. Recently, it has benefited from advancements in deep learning techniques. However, these larger complex approaches cannot manage long-term sequential data and they are charac...
10.1038/s41598-022-15998-7
35,831,393
D005868:Gestures; D006801:Humans; D007802:Language; D021641:Recognition, Psychology; D012813:Sign Language
Scientific reports
2,022
Maturational differences between vascular and bladder smooth muscle during ovine development.
Maturation rates of vascular and visceral smooth muscle (SM) during ovine development were compared by quantifying contractile protein, myosin heavy chain (MHC) isoform contents, and contractile properties of aortas and bladders from female fetal (n = 19) and postnatal (n = 21) sheep. Actin, myosin, and protein content...
10.1152/ajpregu.2000.278.5.R1305
10,801,301
D000199:Actins; D000818:Animals; D001011:Aorta; D003285:Contractile Proteins; D005260:Female; D007537:Isometric Contraction; D024510:Muscle Development; D009124:Muscle Proteins; D009130:Muscle, Smooth; D009131:Muscle, Smooth, Vascular; D018995:Myosin Heavy Chains; D018994:Myosin Light Chains; D009219:Myosin-Light-Chain...
American journal of physiology. Regulatory, integrative and comparative physiology
2,000
D000199:Actins; D003285:Contractile Proteins; D009124:Muscle Proteins; D018994:Myosin Light Chains; D009219:Myosin-Light-Chain Kinase; D018995:Myosin Heavy Chains; D009218:Myosins
Time to Reconsider the Inhaled Drugs for<br /> Tuberculosis.
Null.
10.29271/jcpsp.2022.06.831
35,686,426
D000280:Administration, Inhalation; D006801:Humans; D014376:Tuberculosis
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
2,022
Temporary elective tooth separation as a diagnostic aid in general dental practice.
This study examined the feasibility, acceptability and potential diagnostic value of using a 'blanket' technique for placing elastomeric separators as a diagnostic aid in a general practice situation. Five practices were visited and 211 children between 5 and 15 years were examined. All 211 children accepted the 'clini...
10.1038/sj.bdj.4807281
2,206,652
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004245:DMF Index; D003731:Dental Caries; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D016300:Radiography, Bitewing; D012408:Rubber; D012606:Scotland; D014087:Tooth Movement Techniques
British dental journal
1,990
D012408:Rubber
The Cold Pressor Test as a Predictor of Prolonged Postoperative Pain, a Prospective Cohort Study.
INTRODUCTION Presently, it is difficult to predict which patients are at increased risk of ongoing pain problems postoperatively. This study followed a group of patients from the week before their operation until 3 months after it, to identify potential risk variables. METHODS Fifty-four patients undergoing moderate-...
10.1007/s40122-016-0056-z
27,650,441
Pain and therapy
2,016
Relative Effectiveness of Cell-based Versus Egg-based Quadrivalent Influenza Vaccines in Children and Adolescents in the United States During the 2019-2020 Influenza Season.
BACKGROUND Egg-based influenza vaccine production can lead to the accumulation of mutations that affect antigenicity. The mammalian cell-based inactivated quadrivalent influenza vaccine (IIV4c) may improve effectiveness compared with egg-based vaccines. This study estimated the relative vaccine effectiveness (rVE) of I...
10.1097/INF.0000000000003620
35,797,705
D000293:Adolescent; D000818:Animals; D002648:Child; D006801:Humans; D007252:Influenza Vaccines; D007251:Influenza, Human; D008322:Mammals; D012189:Retrospective Studies; D012621:Seasons; D014481:United States; D014611:Vaccination; D017778:Vaccines, Combined; D015164:Vaccines, Inactivated
The Pediatric infectious disease journal
2,022
D007252:Influenza Vaccines; D017778:Vaccines, Combined; D015164:Vaccines, Inactivated
Different types of arteriovenous anastomoses between femoral artery and vein distal to the island groin flap.
An experimental study was done in rats in which the animals were randomly divided into four groups. Each group included bilateral standard island groin flaps. The right side flap was used as control. On the left side, after elevation of the flap, different types of arteriovenous connections were constructed distal to t...
10.1055/s-2002-30187
12,022,036
D000818:Animals; D001166:Arteriovenous Shunt, Surgical; D005263:Femoral Artery; D005268:Femoral Vein; D006119:Groin; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012039:Regional Blood Flow; D013524:Surgical Flaps
Journal of reconstructive microsurgery
2,002
Analytical solution of l-i SEIR model-Comparison of l-i SEIR model with conventional SEIR model in simulation of epidemic curves.
The Susceptible-Exposed-Infectious-Recovered (SEIR) epidemic model has been commonly used to analyze the spread of infectious diseases. This 4-compartment (S, E, I and R) model uses an approximation of temporal homogeneity of individuals in these compartments to calculate the transfer rates of the individuals from comp...
10.1371/journal.pone.0287196
37,315,097
D006801:Humans; D003141:Communicable Diseases; D003198:Computer Simulation; D000086382:COVID-19; D058872:Epidemics
PloS one
2,023
A window on the physiopathogenesis of seizures in patients with cortical dysplasia.
Cortical dysplasia is found in many cases of intractable epilepsy. Dr. Avoli reports that dysplastic cortex--removed from human brains during seizure surgery--shows abnormal excitability in vitro.
11,993,728
D002540:Cerebral Cortex; D004594:Electrophysiology; D006801:Humans; D019579:Neocortex; D009474:Neurons; D012640:Seizures; D013569:Synapses
Advances in experimental medicine and biology
2,002
Breaking Down the Magnonic Wiedemann-Franz Law in the Hydrodynamic Regime.
Recent experiments have shown an indication of a hydrodynamic magnon behavior in ultrapure ferromagnetic insulators; however, its direct observation is still lacking. Here, we derive a set of coupled hydrodynamic equations and study the thermal and spin conductivities for such a magnon fluid. We reveal the drastic brea...
10.1103/PhysRevLett.130.166201
37,154,651
Physical review letters
2,023
Development of super dimensional stable poplar structure with fire and mildew resistance by delignification/densification of wood with highly aligned cellulose molecules.
Wood is one of the most popular materials for construction purposes because of its environmentally friendly and sustainable characteristics. However, the use of wood is constrained by the lengthy time it takes for trees to mature. Consequently, fast-growing wood species have become popular as substitute options due to ...
10.1016/j.ijbiomac.2023.128572
38,052,291
International journal of biological macromolecules
2,023
Effect of rest on physicians' performance in an emergency department, objectified by electroencephalographic analyses and psychometric tests.
OBJECTIVE The aim of the field study was to objectify physicians' vigilance, well-being, and cognitive performance in the course of 24-hr shifts with and without afternoon rest. SUBJECTS, SETTING, AND DESIGN: Eleven residents (four women, seven men; age, 33.5 +/- 4.7 yrs) were observed when doing two regular 24-hr shif...
10.1097/00003246-200210000-00022
12,394,962
D000328:Adult; D001288:Attention; D002940:Circadian Rhythm; D003071:Cognition; D018592:Cross-Over Studies; D004569:Electroencephalography; D004635:Emergency Medicine; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D008297:Male; D011594:Psychometrics; D012146:Rest; D012647:Self-Assessment; D012890:...
Critical care medicine
2,002
Increased retest reactivity by both patch and use test with methyldibromoglutaronitrile in sensitized individuals.
Hyperreactivity on re-exposure of previous allergic contact dermatitis skin areas has been previously demonstrated. This study aimed to investigate in methyldibromoglutaronitrile (MDBGN) allergic patients whether skin with previous allergic dermatitis from MDBGN showed an augmented response on re-exposure by both a pat...
10.2340/00015555-0009
16,585,981
D000328:Adult; D000368:Aged; D000485:Allergens; D016022:Case-Control Studies; D017449:Dermatitis, Allergic Contact; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009570:Nitriles; D010328:Patch Tests; D011310:Preservatives, Pharmaceutical; D012915:Soaps
Acta dermato-venereologica
2,006
D000485:Allergens; D009570:Nitriles; D011310:Preservatives, Pharmaceutical; D012915:Soaps; C039411:1,2-dibromo-2,4-dicyanobutane
Native Mass Spectrometry: What is in the Name?
Electrospray ionization mass spectrometry (ESI-MS) is nowadays one of the cornerstones of biomolecular mass spectrometry and proteomics. Advances in sample preparation and mass analyzers have enabled researchers to extract much more information from biological samples than just the molecular weight. In particular, rele...
10.1007/s13361-016-1545-3
27,909,974
D000818:Animals; D004247:DNA; D006801:Humans; D008958:Models, Molecular; D011487:Protein Conformation; D055503:Protein Multimerization; D011506:Proteins; D021241:Spectrometry, Mass, Electrospray Ionization
Journal of the American Society for Mass Spectrometry
2,017
D011506:Proteins; D004247:DNA
Unleashing nanofabrication through thermomechanical nanomolding.
Advancements in nanotechnology require the development of nanofabrication methods for a wide range of materials, length scales, and elemental distributions. Today’s nanofabrication methods are typically missing at least one demanded characteristic. Hence, a general method enabling versatile nanofabrication remains elus...
10.1126/sciadv.abi4567
34,797,709
Science advances
2,021
Induction of heme oxygenase-1 protects mouse liver from apoptotic ischemia/reperfusion injury.
Ischemia/reperfusion (I/R) injury is the main cause of primary graft dysfunction of liver allografts. Cobalt-protoporphyrin (CoPP)-dependent induction of heme oxygenase (HO)-1 has been shown to protect the liver from I/R injury. This study analyzes the apoptotic mechanisms of HO-1-mediated cytoprotection in mouse liver...
10.1007/s10495-013-0814-x
23,435,964
D000818:Animals; D017209:Apoptosis; D015415:Biomarkers; D022762:CCAAT-Enhancer-Binding Proteins; D053148:Caspase 3; D019610:Cytoprotection; D004790:Enzyme Induction; D015870:Gene Expression; D051547:Heme Oxygenase-1; D022781:Hepatocytes; D051034:Inhibitor of Apoptosis Proteins; D007274:Injections, Intraperitoneal; D019...
Apoptosis : an international journal on programmed cell death
2,013
D015415:Biomarkers; D022762:CCAAT-Enhancer-Binding Proteins; D051034:Inhibitor of Apoptosis Proteins; D019394:Ki-67 Antigen; D008565:Membrane Proteins; D011524:Protoporphyrins; C007095:cobaltiprotoporphyrin; D051547:Heme Oxygenase-1; C496542:Hmox1 protein, mouse; C505409:Casp3 protein, mouse; D053148:Caspase 3
Rate-dependent left bundle branch block during anaesthesia.
Rate-dependent left bundle branch block during general anaesthesia is rare. Its occurrence makes electrocardiographic diagnosis of acute myocardial ischaemia or infarction difficult. It can also be confused with a slow rate ventricular tachycardia. We present a case of rate-dependent left bundle branch block in a patie...
10.1177/0310057X0403200521
15,535,502
D000768:Anesthesia, General; D002037:Bundle-Branch Block; D002763:Cholecystectomy; D002769:Cholelithiasis; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006329:Heart Conduction System; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D035583:Rare Diseases; D018570:Risk Assessment; D01...
Anaesthesia and intensive care
2,004
[Features of clinical nutrition of patients with anemia in penitentiary institutions].
The problem of psychological and somatic health of convicts is very important for society. Nutrition is one of the factors directly affecting it. In order to respect the rights and legitimate interests of this category of persons in the Russian Federation nowadays, various nutritional standards are distinguished depend...
10.24411/0042-8833-2019-10067
31,860,202
D000328:Adult; D000740:Anemia; D002149:Energy Intake; D005260:Female; D006801:Humans; D008297:Male; D062407:Meals; D009752:Nutritional Status; D009753:Nutritive Value; D011330:Prisons; D012426:Russia
Voprosy pitaniia
2,019
Influence of thyroxine treatment on thyroid size and anti-thyroid peroxidase antibodies in Hashimoto's thyroiditis.
OBJECTIVE It has been postulated that a decrease in thyroid size can be achieved by thyroxine treatment in patients with goitrous Hashimoto's thyroiditis but no objective data are available. We have therefore investigated the influence of thyroxine treatment on ultrasonically determined thyroid size. We also measured s...
10.1111/j.1365-2265.1991.tb03528.x
1,742,880
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies; D005260:Female; D006801:Humans; D007453:Iodide Peroxidase; D008875:Middle Aged; D013961:Thyroid Gland; D013963:Thyroid Hormones; D013967:Thyroiditis, Autoimmune; D013974:Thyroxine; D014463:Ultrasonography
Clinical endocrinology
1,991
D001323:Autoantibodies; D013963:Thyroid Hormones; D007453:Iodide Peroxidase; D013974:Thyroxine
Chromosomal Microarray Analysis in Pregnancies With Corpus Callosum or Posterior Fossa Anomalies.
OBJECTIVE We investigated the detection rate of clinically significant chromosomal microarray analysis (CMA) results in pregnancies with sonographic diagnosis of fetal corpus callosum anomalies (CCA) or posterior fossa anomalies (PFA). METHODS All CMA tests in pregnancies with CCA or PFA performed between January 201...
10.1212/NXG.0000000000000585
34,079,909
Neurology. Genetics
2,021
Hippocampal CA3 NMDA receptors are crucial for adaptive timing of trace eyeblink conditioned response.
Classical conditioning of the eyeblink reflex is a simple form of associative learning for motor responses. To examine the involvement of hippocampal CA3 NMDA receptors (NRs) in nonspatial associative memory, mice lacking an NR1 subunit selectively in adult CA3 pyramidal cells [CA3-NR1 knock-out (KO) mice] were subject...
10.1523/JNEUROSCI.4142-05.2006
16,452,679
D000222:Adaptation, Physiological; D000818:Animals; D001767:Blinking; D003215:Conditioning, Eyelid; D004576:Electromyography; D005108:Extinction, Psychological; D006624:Hippocampus; D007700:Kinetics; D051379:Mice; D018345:Mice, Knockout; D017966:Pyramidal Cells; D016194:Receptors, N-Methyl-D-Aspartate
The Journal of neuroscience : the official journal of the Society for Neuroscience
2,006
C101911:NMDA receptor A1; D016194:Receptors, N-Methyl-D-Aspartate
Aceto-white temporal pattern classification using k-NN to identify precancerous cervical lesion in colposcopic images.
After Pap smear test, colposcopy is the most used technique to diagnose cervical cancer due to its higher sensitivity and specificity. One of the most promising approaches to improve the colposcopic test is the use of the aceto-white temporal patterns intrinsic to the color changes in digital images. However, there is ...
10.1016/j.compbiomed.2009.06.006
19,608,162
D000328:Adult; D000465:Algorithms; D001185:Artificial Intelligence; D003127:Colposcopy; D003198:Computer Simulation; D003936:Diagnosis, Computer-Assisted; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008800:Mexico; D010865:Pilot Projects; D011230:Precancerous Conditions; D002583:Ute...
Computers in biology and medicine
2,009
Piezoelectric Hydrogel for Prophylaxis and Early Treatment of Pressure Injuries/Pressure Ulcers.
Pressure injuries/pressure ulcers (PIs/PUs) are a critical global healthcare issue and represent a considerable burden on healthcare resources. Prevention of PIs/PUs is the least costly approach and minimizes the patient suffering compared with treatment. Besides, sustained tissue load alleviation and microenvironment ...
10.1021/acsbiomaterials.2c00448
35,767,822
D001458:Bandages; D006801:Humans; D020100:Hydrogels; D003668:Pressure Ulcer; D013492:Suppuration
ACS biomaterials science & engineering
2,022
D020100:Hydrogels
DNA extraction and Escherichia coli quantification of anaerobically digested biosolids using the competitive touchdown PCR method.
Accurate enumeration of indicator organisms such as Escherichia coli is important for assessing the safety of water and wastewater samples. Recent research has shown that E. coli can enter a viable but non-culturable state; therefore, traditional cultivation methods could potentially underestimate the quantities of the...
10.1016/j.watres.2006.06.020
16,908,046
D000693:Anaerobiosis; D015169:Colony Count, Microbial; D004269:DNA, Bacterial; D004926:Escherichia coli; D029968:Escherichia coli Proteins; D005968:Glutamate Decarboxylase; D007220:Industrial Waste; D008565:Membrane Proteins; D016133:Polymerase Chain Reaction; D012722:Sewage
Water research
2,006
D004269:DNA, Bacterial; D029968:Escherichia coli Proteins; D007220:Industrial Waste; D008565:Membrane Proteins; D012722:Sewage; C121044:gadA protein, E coli; D005968:Glutamate Decarboxylase
Differential immunohistochemical expression of CD44s, E-cadherin and β-catenin among hyperplastic and neoplastic lesions of the prostate gland.
INTRODUCTION CD44s, E-cadherin and β-catenin are cell adhesion molecules (CAMs) and appear to influence organ development, inflammation, cancer invasion and metastasis. We studied the expression of these CAMs in prostate cancer (PCa), high-grade prostatic intraepithelial neoplasia (HGPIN) and nodular adenomatous hyperp...
10.1159/000345057
23,220,849
D015703:Antigens, CD; D014408:Biomarkers, Tumor; D015820:Cadherins; D016009:Chi-Square Distribution; D006801:Humans; D018960:Hyaluronan Receptors; D007150:Immunohistochemistry; D008297:Male; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D016612:Paraffin Embedding; D011237:Predictive Value of Tests; D011467:Prosta...
Urologia internationalis
2,013
D015703:Antigens, CD; D014408:Biomarkers, Tumor; C497483:CD44 protein, human; C513384:CDH1 protein, human; C495270:CTNNB1 protein, human; D015820:Cadherins; D018960:Hyaluronan Receptors; D051176:beta Catenin
Preserving the humanities in medical education.
Patients are frequently unhappy with medical care because physicians fail to demonstrate humanistic qualities. Immersion in science is a necessary part of medical education but not sufficient. Courses in the history of medicine, the medical narrative in literature, bioethics, medicine and art, and spirituality and medi...
10.3109/01421590903390585
20,095,779
D004501:Education, Medical; D006809:Humanities; D006801:Humans
Medical teacher
2,010
Connectivity alterations of mesostriatal pathways in first episode psychosis.
BACKGROUND AND HYPOTHESIS Pathogenic understanding of the psychotic disorders converges on regulation of dopaminergic signaling in mesostriatocortical pathways. Functional connectivity of the mesostriatal pathways may inform us of the neuronal networks involved. STUDY DESIGN This longitudinal study of first episode p...
10.1038/s41537-023-00339-y
36,918,579
Schizophrenia (Heidelberg, Germany)
2,023
Morphological features of basivertebral foramen among different age groups: Recognition in spine.
Background Basivertebral foramen (BF) is a vessel and nerve passage in the posterior wall of vertebral body (VB). Our goal was to report BF's morphological characteristics in different age groups of mainland Chinese adults and to evaluate the relationship between BF's morphology and factors such as age, gender, heavy w...
10.3389/fsurg.2023.1115654
37,025,270
Frontiers in surgery
2,023
Nonlinear dynamics of a single-gap terahertz split-ring resonator under electromagnetic radiation.
Research into metasurfaces is developing rapidly and is topical due to their importance and applications in various fields such as communications, cryptography, and sensing, to name a few. These materials are artificially engineered to manipulate/control electromagnetic (EM) waves, in order to present a particular func...
10.1063/5.0157489
37,870,998
Chaos (Woodbury, N.Y.)
2,023
Management of allergic conjunctivitis: an evaluation of the perceived comfort and therapeutic efficacy of olopatadine 0.2% and azelastine 0.05% from two prospective studies.
PURPOSE Results from 2 patient-reported outcome studies of allergic conjunctivitis sufferers who used olopatadine 0.2% and azelastine 0.05% are analyzed. METHODS The PACE (Pataday Allergic Conjunctivitis Evaluation) multi-center, prospective, open-label study examined patient perceptions of olopatadine 0.2% once dail...
10.2147/opth.s5223
19,668,586
Clinical ophthalmology (Auckland, N.Z.)
2,009
Differential induction of interleukin-6 production by monocytes, endothelial cells and smooth muscle cells.
Studying the production of IL-6 by monocytes, endothelial cells and smooth muscle cells we observed that cytokine inducers like IL-1, TNF alpha, LPS, SAC and PMA could be divided roughly into two categories. One, that consisted of LPS and SAC, which had a potent IL-6 inducing effect on monocytes and minor or no effect ...
1,924,432
D000911:Antibodies, Monoclonal; D002478:Cells, Cultured; D004730:Endothelium, Vascular; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007375:Interleukin-1; D015850:Interleukin-6; D007700:Kinetics; D008070:Lipopolysaccharides; D009000:Monocytes; D009131:Muscle, Smooth, Vascular; D011994:Recombinant Protein...
Progress in clinical and biological research
1,991
D000911:Antibodies, Monoclonal; D007375:Interleukin-1; D015850:Interleukin-6; D008070:Lipopolysaccharides; D011994:Recombinant Proteins; D014409:Tumor Necrosis Factor-alpha
Extended-spectrum-beta-lactamase production in a Salmonella enterica serotype Typhi strain from the Philippines.
A Salmonella enterica serotype Typhi strain was cultured from blood and fecal samples from a 54-year-old man with fever and diarrhea. He had returned from travel to the Philippines a few days earlier. Phenotypic and genotypic analysis confirmed the production of the SHV-12 extended-spectrum beta-lactamase.
10.1128/JCM.00676-08
18,550,740
D001426:Bacterial Proteins; D001769:Blood; D005243:Feces; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010679:Philippines; D012485:Salmonella typhi; D014195:Travel; D014435:Typhoid Fever; D018440:beta-Lactam Resistance; D001618:beta-Lactamases
Journal of clinical microbiology
2,008
D001426:Bacterial Proteins; C107198:beta-lactamase SHV-12; D001618:beta-Lactamases
Experimental and Monte Carlo dosimetric characterization of a 1 cm (103)Pd brachytherapy source.
PURPOSE To determine the in-air azimuthal anisotropy and in-water dose distribution for the 1 cm length of a new elongated (103)Pd brachytherapy source through both experimental measurements and Monte Carlo (MC) simulations. Measured and MC-calculated dose distributions were used to determine the American Association o...
24,880,585
D016880:Anisotropy; D001918:Brachytherapy; D006801:Humans; D009010:Monte Carlo Method; D010165:Palladium; D011868:Radioisotopes; D011874:Radiometry; D013819:Thermoluminescent Dosimetry; D035501:Uncertainty
Brachytherapy
2,014
D011868:Radioisotopes; D010165:Palladium
Shape and motion from image streams: a factorization method.
Inferring scene geometry and camera motion from a stream of images is possible in principle, but it is an ill-conditioned problem when the objects are distant with respect to their size. We have developed a factorization method that can overcome this difficulty by recovering shape and motion without computing depth as ...
10.1073/pnas.90.21.9795
11,607,434
Proceedings of the National Academy of Sciences of the United States of America
1,993
Placement of peripherally inserted central catheters in the cardiac catheterization laboratory.
This report describes our experiences with three patients requiring several weeks of central venous access for various intravenous therapies. These particular patients posed a considerable challenge for bedside placement of a peripherally inserted central catheter, so the catheters were placed in the cardiac catheteriz...
10.1002/(sici)1097-0304(199706)41:2<189::aid-ccd18>3.0.co;2-l
9,184,295
D000368:Aged; D000369:Aged, 80 and over; D006328:Cardiac Catheterization; D002405:Catheterization, Central Venous; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
Catheterization and cardiovascular diagnosis
1,997
Sufficient Competence to Enter the Unsupervised Practice of Orthopaedics: What Is It, When Does It Occur, and Do We Know It When We See It? AOA Critical Issues.
The goal of residency programs is to provide an educational venue with graduated responsibility and increasing levels of independence as preparation for entering the unsupervised practice of medicine. Surgical programs are required to both cultivate and convey skills pursuant to three fundamental domains: a sufficient ...
10.2106/JBJS.O.00025
26,333,742
D000068:Accreditation; D002170:Canada; D002983:Clinical Competence; D003162:Competency-Based Education; D006801:Humans; D007396:Internship and Residency; D009985:Orthopedics; D006113:United Kingdom; D014481:United States
The Journal of bone and joint surgery. American volume
2,015
Autophagy involved in antiviral activity of sodium tanshinone IIA sulfonate against porcine reproductive and respiratory syndrome virus infection in vitro.
BACKGROUND In previous research, we have demonstrated that sodium tanshinone IIA sulfonate (STS) has anti-porcine reproductive and respiratory syndrome virus (PRRSV) activity, but whether autophagy is involved in this process is still unknown. In this study, the autophagy effect of STS against PRRSV infection was inves...
10.3851/IMP3268
30,272,564
D000818:Animals; D000998:Antiviral Agents; D001343:Autophagy; D000071187:Autophagy-Related Protein 5; D000071193:Autophagy-Related Protein 7; D000071183:Autophagy-Related Proteins; D000071186:Beclin-1; D002460:Cell Line; D066298:In Vitro Techniques; D019590:Nucleocapsid Proteins; D010616:Phenanthrenes; D019316:Porcine ...
Antiviral therapy
2,019
D000998:Antiviral Agents; D000071187:Autophagy-Related Protein 5; D000071183:Autophagy-Related Proteins; D000071186:Beclin-1; D019590:Nucleocapsid Proteins; D010616:Phenanthrenes; C024894:tanshinone II A sodium sulfonate; D000071193:Autophagy-Related Protein 7
[Methods for microbiological control of textiles].
Our laboratory is requested more and more by the establishments of health and the industrial laundries for the microbiological realization of control on the textile articles after completion. We checked the effectiveness of the techniques of the bacteriol prints or rodac and the bacterial extraction after maceration fo...
10.1684/abc.2008.0202
18,390,428
D001419:Bacteria; D001431:Bacteriological Techniques; D006761:Hospitals; D006801:Humans; D006920:Hygiene; D007846:Laundering; D007847:Laundry Service, Hospital; D011786:Quality Control; D013211:Staphylococcus aureus; D013784:Textiles; D014465:Ultrasonics
Annales de biologie clinique
2,008
Bismuth germanate as a perspective material for dielectric resonators in EPR spectroscopy.
High purity bismuth germanate (Bi4(GeO4)3, BGO) is proposed and implemented as an alternative material for dielectric EPR resonators. A significant improvement of the absolute sensitivity can be readily achieved by substituting the alumina insert (ring) by BGO-made one in commercially available X-band EPR probeheads. F...
27,569,694
Journal of magnetic resonance (San Diego, Calif. : 1997)
2,016
A model theoretical study on ligand exchange reactions of CooA.
Rr-CooA is a CO-sensor heme protein, where binding of CO with the heme group stimulates a transcriptional activator activity of CooA. In this process, the heme undergoes a series of ligand exchanges. In the ferric form, the heme has Cys75 and Pro2 as the axial ligands. In the reduced ferrous form, the heme has His77 in...
10.1039/c3cp43253j
23,511,331
D001426:Bacterial Proteins; D002248:Carbon Monoxide; D003545:Cysteine; D005290:Ferric Compounds; D005296:Ferrous Compounds; D005740:Gases; D006418:Heme; D006420:Hemeproteins; D008024:Ligands; D008958:Models, Molecular; D011789:Quantum Theory; D012247:Rhodospirillum rubrum; D015534:Trans-Activators
Physical chemistry chemical physics : PCCP
2,013
D001426:Bacterial Proteins; C108776:CooA protein, Rhodospirillum rubrum; D005290:Ferric Compounds; D005296:Ferrous Compounds; D005740:Gases; D006420:Hemeproteins; D008024:Ligands; D015534:Trans-Activators; D006418:Heme; D002248:Carbon Monoxide; D003545:Cysteine
Linkage of NCHS Population Health Surveys to Administrative Records From Social Security Administration and Centers for Medicare Medicaid Services.
Federally sponsored health surveys are a critical source of information on public health in the United States. The National Center for Health Statistics (NCHS) is the nation's principal health statistics agency and is responsible for collecting accurate, relevant, and timely data. NCHS conducts several population-based...
26,375,817
D014487:Centers for Medicare and Medicaid Services, U.S.; D006306:Health Surveys; D006801:Humans; D008498:Medical Record Linkage; D009309:National Center for Health Statistics, U.S.; D011634:Public Health; D014481:United States; D019131:United States Social Security Administration
Vital and health statistics. Ser. 1, Programs and collection procedures
2,015
Immunosuppressive macrophages induced by IDO1 promote the growth of endometrial stromal cells in endometriosis.
It was previously demonstrated that anomalous expression of indoleamine 2,3-dioxygenase-1 (IDO1) in endometrial stromal cells (ESCs) stimulated an inflammatory response that subsequently initiated the activation of immunosuppressive macrophages in endometriosis. The aim of the present study was to clarify the effect of...
10.3892/mmr.2017.6242
28,260,094
D000328:Adult; D017209:Apoptosis; D049109:Cell Proliferation; D018920:Coculture Techniques; D004715:Endometriosis; D004717:Endometrium; D005260:Female; D006801:Humans; D050503:Indoleamine-Pyrrole 2,3,-Dioxygenase; D008264:Macrophages; D010587:Phagocytosis; D017154:Stromal Cells; D055815:Young Adult
Molecular medicine reports
2,017
C576710:IDO1 protein, human; D050503:Indoleamine-Pyrrole 2,3,-Dioxygenase
Anaerobic, non-clostridial fasciitis and myonecrosis of the abdominal wall. Pure anaerobic infection originating from neglected inflammation of an urachal remnant.
A pure anaerobic infection of the abdominal wall of a 40-year-old man is described. The infection originated from an urachal remnant. Seven different bacterial strains were isolated. Even though no clostridia were involved, the infection caused extensive necrosis of the abdominal wall including both fascia and muscles.
10.3109/inf.1979.11.issue-3.14
160,616
D000009:Abdominal Muscles; D000328:Adult; D001424:Bacterial Infections; D005205:Fascia; D006801:Humans; D007249:Inflammation; D008297:Male; D009336:Necrosis; D014497:Urachus
Scandinavian journal of infectious diseases
1,979
Factors Affecting the Agreement Between Emergency Psychiatrists and General Practitioners Regarding Involuntary Psychiatric Hospitalizations.
Important discrepancies exist between physicians in deciding when to perform involuntary hospitalization measures (IHMs). The factors underlying these differences are poorly known.We conducted a two-year single-center retrospective study in France on patients who were referred to the emergency department (ED) with an I...
10.1038/srep28134
27,324,574
D000328:Adult; D000428:Alcohol Drinking; D001714:Bipolar Disorder; D000066491:Clinical Decision-Making; D032921:Consensus; D003866:Depressive Disorder; D004636:Emergency Service, Hospital; D005260:Female; D005602:France; D058005:General Practitioners; D006801:Humans; D000074441:Involuntary Treatment; D000076083:Involun...
Scientific reports
2,016
Outcome analysis and risk factors for postoperative colonic ischaemia after aortic surgery.
PURPOSE Colonic ischaemia (CI) represents a serious complication after aortic surgery. This study aimed to analyse risk factors and outcome of patients suffering from postoperative CI. METHODS Data of 1404 patients who underwent aortic surgery were retrospectively analysed regarding CI occurrence. Co-morbidities, pro...
10.1007/s00423-020-01964-2
32,827,052
D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal; D001019:Aortic Rupture; D019917:Blood Vessel Prosthesis Implantation; D005260:Female; D006801:Humans; D007511:Ischemia; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors...
Langenbeck's archives of surgery
2,020
Participant Characteristics Associated with High Responsiveness to Personalized Healthy Food Incentives: a Secondary Analysis of the Randomized Controlled Crossover Smart Cart Study.
BACKGROUND Personalized dietary behavioral interventions could be enhanced by understanding factors accounting for individual variability in dietary decisions. OBJECTIVE This study was a secondary analysis of the Smart Cart randomized controlled trial to determine whether participant characteristics predicted high re...
10.1093/jn/nxac197
36,040,345
D006801:Humans; D005260:Female; D008297:Male; D009042:Motivation; D018592:Cross-Over Studies; D004032:Diet; D005502:Food; D005518:Food Preferences
The Journal of nutrition
2,023
Autocrine growth of human B lymphocytes: maintained response to autostimulatory factors is the special feature of immortalization by Epstein-Barr virus--a hypothesis.
The autocrine growth profile of human B lymphocytes transformed with Epstein-Barr virus (EBV) was found to comprise three distinct components: a B-cell growth factor (BCGF); an interleukin-1 (IL-1)-like activity; an activity requiring cell-to-cell contact for its action. Observations on the inhibition of the EBV-carryi...
10.1007/BF02935004
3,027,466
D001402:B-Lymphocytes; D002450:Cell Communication; D002455:Cell Division; D002472:Cell Transformation, Viral; D006133:Growth Substances; D004854:Herpesvirus 4, Human; D006801:Humans; D007375:Interleukin-1; D015847:Interleukin-4; D007700:Kinetics; D008222:Lymphokines; D008970:Molecular Weight; D019948:Receptors, Interle...
Medical oncology and tumor pharmacotherapy
1,986
D006133:Growth Substances; D007375:Interleukin-1; D008222:Lymphokines; D019948:Receptors, Interleukin-4; D011975:Receptors, Mitogen; D015847:Interleukin-4
Integrating the contributions of mitochondrial oxidative metabolism to lipotoxicity and inflammation in NAFLD pathogenesis.
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing globally. NAFLD includes non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH). NASH is the pathological form of the disease characterized by liver steatosis, inflammation, cell injury, and fibrosis. A fundamental contributor ...
10.1016/j.bbalip.2022.159209
35,934,297
D018450:Disease Progression; D006801:Humans; D007249:Inflammation; D008055:Lipids; D008103:Liver Cirrhosis; D065626:Non-alcoholic Fatty Liver Disease; D018384:Oxidative Stress
Biochimica et biophysica acta. Molecular and cell biology of lipids
2,022
D008055:Lipids
Defect-Controlled Formation of Triclinic Na2 CoP2 O7 for 4 V Sodium-Ion Batteries.
Simple defects such as sodium deficiencies can induce the selective synthesis of triclinic Na2 CoP2 O7 , providing an increase in energy density of more than 40 % compared to the stoichiometric polymorph that is preferentially formed under the commonly used synthesis conditions. Such a significant improvement, which wa...
10.1002/anie.201601022
27,098,851
Angewandte Chemie (International ed. in English)
2,016
Serial learning by rhesus monkeys: I. Acquisition and retention of multiple four-item lists.
Two rhesus monkeys were trained to learn eight 4-item lists, each composed of 4 different photographs. Lists were trained in successive phases: A, A----B, A----B----C, and A----B----C----D. After List 4, retention, as measured by the method of savings, was, on average, 66% (range: 44-84%). Indeed, all 4 lists could be ...
10.1037//0097-7403.17.4.396
1,744,595
D000818:Animals; D001288:Attention; D008253:Macaca mulatta; D008297:Male; D011939:Mental Recall; D010364:Pattern Recognition, Visual; D012153:Retention, Psychology; D012691:Serial Learning
Journal of experimental psychology. Animal behavior processes
1,991
A meta-analysis of ultra-high field glutamate, glutamine, GABA and glutathione 1HMRS in psychosis: Implications for studies of psychosis risk.
Ultra-high field proton magnetic resonance spectroscopy (1HMRS) offers a unique opportunity to measure the concentration of neurometabolites implicated in psychosis (PSY). The extant 7 T 1HMRS literature measuring glutamate-associated neurometabolites in the brain in PSY in vivo is small, but a comprehensive, quantitat...
10.1016/j.schres.2020.06.028
32,723,493
D000293:Adolescent; D018698:Glutamic Acid; D005973:Glutamine; D005978:Glutathione; D006801:Humans; D011618:Psychotic Disorders; D005680:gamma-Aminobutyric Acid
Schizophrenia research
2,020
D005973:Glutamine; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D005978:Glutathione
Role of shelterin in cancer and aging.
Mammalian telomeres are formed by tandem repeats of the TTAGGG sequence bound by a specialized six-protein complex known as shelterin, which has fundamental roles in the regulation of telomere length and telomere capping. In the past, the study of mice genetically modified for telomerase components has been instrumenta...
10.1111/j.1474-9726.2010.00596.x
20,569,239
D000375:Aging; D000818:Animals; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms; D019098:Telomerase; D016615:Telomere; D034501:Telomere-Binding Proteins
Aging cell
2,010
D034501:Telomere-Binding Proteins; D019098:Telomerase
Structure-activity relationship of 17 structural analogues of n-butyric acid upon c-myc expression.
Terminal differentiation of hematopoietic cells in vivo and in vitro is almost invariably accompanied by down-regulated expression of the c-myc proto-oncogene. Constitutive expression of c-myc in tumor cells inhibits terminal differentiation and maintains proliferation. In Burkitt's lymphoma, chromosomal translocations...
10.1002/(SICI)1097-0215(19960904)67:5<724::AID-IJC22>3.0.CO;2-3
8,782,665
D000818:Animals; D000970:Antineoplastic Agents; D002051:Burkitt Lymphoma; D002087:Butyrates; D020148:Butyric Acid; D002454:Cell Differentiation; D005227:Fatty Acids; D015972:Gene Expression Regulation, Neoplastic; D016259:Genes, myc; D051379:Mice; D015394:Molecular Structure; D011422:Propionates; D012333:RNA, Messenger...
International journal of cancer
1,996
D000970:Antineoplastic Agents; D002087:Butyrates; D005227:Fatty Acids; D011422:Propionates; D012333:RNA, Messenger; D020148:Butyric Acid; C007022:3-chloropropionic acid
Risk factors associated with the recent cholera outbreak in Yemen: a case-control study.
OBJECTIVES The cholera outbreak in Yemen has become the largest in the recent history of cholera records, having reached more than 1.4 million cases since it started in late 2016. This study aimed to identify risk factors for cholera in this outbreak. METHODS A case-control study was conducted in Aden in 2018 to inve...
10.4178/epih.e2019015
31,010,279
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002771:Cholera; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D015006:Yemen; D055815:Young Adult
Epidemiology and health
2,019
Corticotropin-releasing factor projections from limbic forebrain and paraventricular nucleus of the hypothalamus to the region of the ventral tegmental area.
Corticotropin-releasing factor (CRF) is a peptide neurotransmitter with high numbers of cell bodies found in limbic regions of the rat brain including the oval nucleus of the bed nucleus of the stria terminalis (BNSTov) and central nucleus of the amygdala (CeA) as well as in the paraventricular nucleus of the hypothala...
10.1016/j.neuroscience.2007.09.043
17,961,928
D000344:Afferent Pathways; D000818:Animals; D002452:Cell Count; D003346:Corticotropin-Releasing Hormone; D008297:Male; D010286:Paraventricular Hypothalamic Nucleus; D016548:Prosencephalon; D051381:Rats; D017208:Rats, Wistar; D013266:Stilbamidines; D017557:Ventral Tegmental Area
Neuroscience
2,007
C049774:2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt; D013266:Stilbamidines; D003346:Corticotropin-Releasing Hormone
Remote cerebellar hemorrhage after a spinal surgery complicated by dural tear: case report and literature review.
OBJECTIVE AND IMPORTANCE This report presents a case in which cerebellar hemorrhage occurred after lumbar decompression surgery that was complicated by dural tear and prolonged cerebrospinal fluid leakage. Remote cerebellar hemorrhage after spinal surgery is extremely rare. Our objective is to describe this unusual com...
10.1227/01.neu.0000163688.17385.9b
15,987,597
D000368:Aged; D020201:Brain Hemorrhage, Traumatic; D019299:Decompression, Surgical; D004388:Dura Mater; D005260:Female; D006801:Humans; D007796:Laminectomy; D008159:Lumbar Vertebrae; D012421:Rupture; D013353:Subdural Effusion; D016896:Treatment Outcome
Neurosurgery
2,005
Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer.
The mTORC1 inhibitors, such as rapamycin and its analogs, show limited antitumor activity in clinic, reasons for which have not been clearly elucidated. Here, we undertook an effort to uncover the mechanisms underlying the limited efficacy of rapamycin, and found that the transit suppression of 4EBP1 phosphorylation le...
10.7150/ijbs.32489
31,182,914
D015153:Blotting, Western; D001943:Breast Neoplasms; D045744:Cell Line, Tumor; D000068338:Everolimus; D006801:Humans; D007150:Immunohistochemistry; D047468:Immunoprecipitation; D061986:MCF-7 Cells; D000076222:Mechanistic Target of Rapamycin Complex 1; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Pro...
International journal of biological sciences
2,019
D000068338:Everolimus; D000076222:Mechanistic Target of Rapamycin Complex 1; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt; C403243:SGK3 protein, human; D020123:Sirolimus
Deformation and fracture of crystalline tungsten and fabrication of composite STM probes.
Fracturing microscale constrictions in metallic wires, such as tungsten, platinum, or platinum-iridium, is a common fabrication method used to produce atomically sharp tips for scanning tunneling microscopy (STM), field-emission microscopy and field ion microscopy. Typically, a commercial polycrystalline drawn wire is ...
10.1016/j.ultramic.2020.113083
32,739,752
Ultramicroscopy
2,020
Protocol-driven Antibiotic Treatment of Pediatric Empyema After Fibrinolysis.
BACKGROUND The duration of antibiotic treatment after resolution of empyema in children is variable. We evaluated the efficacy and safety of a protocol-driven antibiotic regimen aimed to decrease antibiotic duration following treatment with fibrinolysis. METHODS Our institutional protocol consisted of 7 further days ...
10.1097/INF.0000000000002872
32,852,350
D000900:Anti-Bacterial Agents; D001424:Bacterial Infections; D002648:Child; D002675:Child, Preschool; D016724:Empyema, Pleural; D005260:Female; D006801:Humans; D007223:Infant; D007902:Length of Stay; D008297:Male; D011446:Prospective Studies; D013907:Thoracostomy; D015912:Thrombolytic Therapy
The Pediatric infectious disease journal
2,021
D000900:Anti-Bacterial Agents
Reasoning versus text processing in the Wason selection task: a nondeontic perspective on perspective effects.
We argue that perspective effects in the Wason four-card selection task are a product of the linguistic interpretation of the rule in the context of the problem text and not of the reasoning process underlying card selection. In three experiments, participants recalled the rule they used in either a selection or a plau...
10.3758/bf03209354
11,105,532
D001288:Attention; D003210:Concept Formation; D006801:Humans; D011939:Mental Recall; D011340:Problem Solving; D011932:Reading
Memory & cognition
2,000
Molecular characterization of the first community-acquired methicillin-resistant Staphylococcus aureus strains from Central Iran.
BACKGROUND Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has spread throughout the world with varying regional incidences and different staphylococcal cassette chromosome mec (SCCmec) elements in different genetic backgrounds. No information is available on CA-MRSA in Iran. A cross-sectional ...
23,706,379
D000293:Adolescent; D000328:Adult; D017714:Community-Acquired Infections; D005260:Female; D006801:Humans; D007492:Iran; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D008826:Microbial Sensitivity Tests; D058885:Multilocus Sequence Typing; D013203:Staphylococcal Infections; D037521:Virulence Factors...
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2,013
D037521:Virulence Factors
[A Police Perspective on the Interaction with Individuals with Mental Disorders].
OBJECTIVE Police officers often come in contact with individuals suffering from behavior disturbances. The present study examined the subjective experience of these interactions from a police perspective to detect further needs in police trainings to make these interactions safer. METHODS N = 958 police officers fill...
10.1055/a-1190-7598
32,659,794
D001008:Anxiety Disorders; D005858:Germany; D006801:Humans; D001523:Mental Disorders; D008603:Mental Health; D016495:Police; D057545:Social Stigma
Psychiatrische Praxis
2,021
Traumatic posterior luxation of the hip.
The long-term outcome of treatment of posterior hip dislocations was studied in 60 patients. Thirty-two patients had concomitant fractures of the acetabular rim and seven had also femoral head fractures. Treatment consisted of immediate reduction, followed by gentle traction during one week and progressive weight-beari...
2,255,405
D000063:Accidents, Traffic; D000077:Acetabulum; D000328:Adult; D005270:Femur Head; D005593:Fracture Fixation, Internal; D050723:Fractures, Bone; D006617:Hip Dislocation; D006620:Hip Fractures; D006801:Humans; D008297:Male; D011379:Prognosis; D014143:Traction
The Netherlands journal of surgery
1,990
Effect of salinity on tissue architecture in expanding wheat leaves.
Salinity greatly reduces the leaf cross-sectional area of wheat (Triticum aestivum L.) during its development, which may lead to variation in the architectural properties of growing leaves that would result in a change in leaf physiological functions. Our objective was to characterize the effect of salinity on the spat...
10.1007/s00425-004-1401-8
15,503,127
D007091:Image Processing, Computer-Assisted; D008853:Microscopy; D018515:Plant Leaves; D012965:Sodium Chloride; D014908:Triticum
Planta
2,005
D012965:Sodium Chloride
Systematic revision of Hydnum species in Japan.
Hydnum (Hydnaceae, Basidiomycota) exhibits endemic species diversity in East Asia; however, few comprehensive systematic studies have been conducted to date. Here, we performed morphological, ecological, phylogenetic, and biological evaluations of the taxonomy of Hydnum species in Japan. In total, 186 Japanese Hydnum s...
10.1080/00275514.2021.2024407
35,394,899
D001487:Basidiomycota; D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer; D007564:Japan; D010802:Phylogeny; D012340:RNA, Ribosomal, 5.8S; D017422:Sequence Analysis, DNA
Mycologia
2,022
D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer; D012340:RNA, Ribosomal, 5.8S
AIDS and medical confidentiality.
In summary, I have argued that the arguments offered or hinted at in favour of doctors' breaking medical confidentiality by passing on information about their patients' HIV state to others, including other doctors, when this is against the patient's considered wishes are generally unconvincing. Although in highly excep...
10.1136/bmj.294.6588.1675
3,113,584
D000163:Acquired Immunodeficiency Syndrome; D003219:Confidentiality; D028663:Ethical Theory; D004992:Ethics, Medical; D006801:Humans; D007348:Insurance, Health; D008131:London; D010821:Physicians, Family; D011320:Primary Health Care; D018570:Risk Assessment; D012935:Social Justice; D014342:Truth Disclosure
British medical journal (Clinical research ed.)
1,987
Nitric oxide fumigation stimulates flavonoid and phenolic accumulation and enhances antioxidant activity of mushroom.
The effects of nitric oxide (NO) on antioxidant activity and contents of phenolics and flavonoids in mushroom Russula griseocarnosa were investigated. Freshly harvested mushrooms were fumigated with 0, 10, 20 and 30μLL(-1) NO at 20°C for 2h and then taken to examine the antioxidant activities using assays of reducing p...
10.1016/j.foodchem.2012.05.055
22,953,846
D000363:Agaricales; D000975:Antioxidants; D005419:Flavonoids; D005651:Fumigation; D005656:Fungal Proteins; D009569:Nitric Oxide; D010636:Phenols; D015854:Up-Regulation
Food chemistry
2,012
D000975:Antioxidants; D005419:Flavonoids; D005656:Fungal Proteins; D010636:Phenols; D009569:Nitric Oxide
Initial investigation of the efficacy and biosafety of sodium hyaluronate (Healon) as an aid to electrode array insertion.
Sodium hyaluronate has potential uses as an electrode lubricant in cochlear implant surgery. Deeper electrode insertions were achieved in six temporal bones implanted with sodium hyaluronate, compared to 22 patients implanted without sodium hyaluronate. Preliminary biosafety studies measuring hearing thresholds of six ...
7,668,749
D000818:Animals; D001309:Auditory Threshold; D002415:Cats; D003054:Cochlear Implants; D004567:Electrodes, Implanted; D016057:Evoked Potentials, Auditory, Brain Stem; D006801:Humans; D006820:Hyaluronic Acid; D066298:In Vitro Techniques; D013701:Temporal Bone
The Annals of otology, rhinology & laryngology. Supplement
1,995
D006820:Hyaluronic Acid
Is the menopausal transition stressful? Observations of perceived stress from the Seattle Midlife Women's Health Study.
OBJECTIVE To describe changes in the levels of perceived stress in relation to menopausal transition (MT)-related factors (MT stage, hot flash severity, urinary estrone glucuronide, urinary follicle-stimulating hormone, hormone therapy), aging and age-related changes, and psychosocial factors (income adequacy, role bur...
10.1097/gme.0b013e31817ed261
18,725,864
D000375:Aging; D003863:Depression; D004651:Employment; D015914:Estrogen Replacement Therapy; D004970:Estrone; D005260:Female; D005640:Follicle Stimulating Hormone; D020719:Glucuronides; D006304:Health Status; D019584:Hot Flashes; D006801:Humans; D007182:Income; D008593:Menopause; D008875:Middle Aged; D016487:Parenting;...
Menopause (New York, N.Y.)
2,009
D020719:Glucuronides; D004970:Estrone; D005640:Follicle Stimulating Hormone
Supramolecular chirality and chiral inversion of tetraphenylsulfonato porphyrin assemblies on optically active polylysine.
The self-assembly and induced supramolecular chirality of a dianionic meso-tetraphenylsulfonato porphyrin (TPPS) on the optically active polylysine has been investigated. Our research has confirmed that in the presence of poly(l-lysine) (PLL) or poly(d-lysine) (PDL), TPPS could form both H and J aggregates and the exci...
10.1021/jp902870f
19,827,847
D002942:Circular Dichroism; D011107:Polylysine; D011166:Porphyrins; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
The journal of physical chemistry. B
2,009
D011166:Porphyrins; D011107:Polylysine; C049692:tetraphenylporphine
Surgical management of intracranial arachnoid cysts in pediatric patients: radiological and clinical outcome.
OBJECTIVE Congenital intracranial cysts account for a significant portion of intracranial lesions in the pediatric population. The efficiency of surgical treatment in a pediatric cohort with intracranial arachnoid cysts (ACs) at different locations regarding clinical symptoms and mass effect was evaluated. METHODS A ...
10.3171/2020.10.PEDS20839
33,930,866
Journal of neurosurgery. Pediatrics
2,021
Study of Chloride Ion Diffusion in Coral Aggregate Seawater Concrete with Different Water-Cement Ratios under Load.
This study was conducted to investigate the chloride ion transport in coral aggregate seawater concrete (CASC) with varying water-cement ratios under different loads. The ultimate compressive strength was obtained by conducting compression testing of three groups of CASC with different water-cement ratios. Steady loads...
10.3390/ma16020869
36,676,606
Materials (Basel, Switzerland)
2,023
Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway.
Multiple myeloma (MM) is a hematologic malignancy associated with malignant plasma cell proliferation in the bone marrow. Despite the available treatments, drug resistance and adverse side effects pose significant challenges, underscoring the need for alternative therapeutic strategies. Natural products, like the funga...
10.1002/cbin.12101
37,885,161
Cell biology international
2,023
Limited angle C-arm tomography and segmentation for guidance of atrial fibrillation ablation procedures.
Angiographic projections of the left atrium (LA) and the pulmonary veins (PV) acquired with a rotational C-arm system are used for 3D image reconstruction and subsequent automatic segmentation of the LA and PV to be used as roadmap in fluoroscopy guided LA ablation procedures. Acquisition of projections at high oblique...
10.1007/978-3-642-33415-3_78
23,285,605
D000465:Algorithms; D000792:Angiography; D001281:Atrial Fibrillation; D001331:Automation; D002138:Calibration; D054893:Cone-Beam Computed Tomography; D003952:Diagnostic Imaging; D005471:Fluoroscopy; D006325:Heart Atria; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D01...
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
2,012
African striped mice.
Mallarino et al. introduce the African striped mouse, which is being used in a number of fields of research, including animal behavior, evolutionary developmental biology, and chronobiology.
10.1016/j.cub.2018.02.009
29,614,283
D000818:Animals; D001522:Behavior, Animal; D005075:Biological Evolution; D019521:Body Patterning; D002909:Chronobiology Phenomena; D015509:Developmental Biology; D051379:Mice; D012919:Social Behavior
Current biology : CB
2,018
Influence of outer geometry on primary stability for uncemented acetabular shells in developmental dysplasia of the hip.
Excellent primary stability of uncemented acetabular shells is essential to obtain successful clinical outcomes. However, in the case of developmental dysplasia of the hip (DDH), aseptic loosening may be induced by instability due to a decrease of the contact area between the acetabular shell and host bone. The aim of ...
10.1177/0954411920960000
32,996,400
D000077:Acetabulum; D019644:Arthroplasty, Replacement, Hip; D000082602:Developmental Dysplasia of the Hip; D006622:Hip Prosthesis; D006801:Humans; D012086:Reoperation
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
2,021
The Role of Plastic Surgery at an Academic Medical Center in the United States.
BACKGROUND Plastic surgery may have traditionally been labelled as a "less essential" service at many academic medical centers in the United States. The purpose of this study is to evaluate the role of the plastic surgery team as a valuable service at an academic medical center. METHODS We performed a 10-year retrosp...
10.1097/SAP.0000000000001052
28,272,146
D000046:Academic Medical Centers; D000368:Aged; D000369:Aged, 80 and over; D002140:California; D005260:Female; D006258:Head and Neck Neoplasms; D006801:Humans; D007629:Kentucky; D007869:Leg Injuries; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases; D010819:Physician's Role; D010818:Practice Patt...
Annals of plastic surgery
2,017
The prognostic impact of perioperative blood transfusion on survival in patients with bladder urothelial carcinoma treated with radical cystectomy.
PURPOSE The aim of our study was to assess the influence of perioperative blood transfusion (PBT) on survival outcomes following radical cystectomy (RC) and pelvic lymph node dissection (PLND). MATERIALS AND METHODS We reviewed and analyzed the clinical data of 432 patients who underwent RC for bladder cancer from 19...
10.4111/kju.2015.56.4.295
25,874,043
D000368:Aged; D001803:Blood Transfusion; D002295:Carcinoma, Transitional Cell; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D010388:Pelvis; D019990:Perioperative Care; D011379:Prognosis; D056910:Republic of ...
Korean journal of urology
2,015
Diagnosis and Treatment Options for Inflammatory Skin Conditions of the Lower Extremity.
The lower extremity presents several challenges from a dermatologic standpoint: there are different anatomic areas that not only vary from a stratum corneum thickness and histologic standpoint but are also subject to trauma that is unique (shoe gear, gait cycle). Attention to appropriate diagnosis and management is alw...
10.1016/j.cpm.2019.06.008
31,466,575
D005260:Female; D005533:Foot Dermatoses; D006801:Humans; D008297:Male; D009260:Nail Diseases; D055815:Young Adult
Clinics in podiatric medicine and surgery
2,019
Artificial Rod and Cone Photoreceptors with Human-Like Spectral Sensitivities.
Photosensitive materials contain biologically engineered elements and are constructed using delicate techniques, with special attention devoted to efficiency, stability, and biocompatibility. However, to date, no photosensitive material has been developed to replace damaged visual-systems to detect light and transmit t...
10.1002/adma.201706764
29,775,503
Advanced materials (Deerfield Beach, Fla.)
2,018
Chronic kidney disease patients' views of readiness and ability to use mHealth apps.
BACKGROUND The use of mobile health (mHealth) applications, which provide opportunities to improve health and lessen health inequalities, is increasing. Studies assessing the readiness and ability of patients in Malaysia with chronic kidney disease (CKD) to use mobile phone apps to manage their health are limited. AI...
10.12968/bjon.2023.32.2.74
36,715,528
D006801:Humans; D003430:Cross-Sectional Studies; D051436:Renal Insufficiency, Chronic; D063731:Mobile Applications; D017216:Telemedicine; D007297:Inpatients
British journal of nursing (Mark Allen Publishing)
2,023
Oxoiron(IV)-dominated Heterogeneous Fenton-like Mechanism of Fe-Doped MoS2.
Oxoiron(IV) species are a critical intermediate in the Fe-based Fenton-like process at circumneutral pH, and its oxidative reactivity is closely related to the ligands. An optional inorganic host material, MoS2 , is selected to construct a highly reactive sulfur ligand coordinated Fe species in this work. The Fe specie...
10.1002/asia.202201134
36,459,407
D007501:Iron; D008982:Molybdenum; D010084:Oxidation-Reduction
Chemistry, an Asian journal
2,023
D007501:Iron; D008982:Molybdenum
Novel Nutrition Education Approaches for Health Promotion: From Investigating Problems to Finding Solutions.
The aim of the Nutrients Special Issue "Implications of Nutrition Education, for Health, Behavior, and Lifestyle" is to publish original research articles and reviews that report the design and implementation of nutrition education intervention programs and their effectiveness in terms of lifestyle, health, and wellbei...
10.3390/nu13124423
34,959,974
D001521:Behavior Therapy; D006266:Health Education; D006293:Health Promotion; D006801:Humans; D044623:Nutrition Therapy
Nutrients
2,021