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Liposomes as carriers of imaging agents. | This review discusses the utilization of liposomes as imaging agents or as vehicles for contrast materials. The initial approach was the use of radiolabeled liposomes for scintigraphy. To this end liposomes were either labeled in the lipid membrane or aqueous radiotracers were incorporated inside the lipid vesicles. Th... | 3,913,524 | D006801:Humans; D007553:Isotope Labeling; D008081:Liposomes; D008099:Liver; D009682:Magnetic Resonance Spectroscopy; D009369:Neoplasms; D011868:Radioisotopes; D011877:Radionuclide Imaging | Critical reviews in therapeutic drug carrier systems | 1,985 | D008081:Liposomes; D011868:Radioisotopes | |
Analysis of viscous losses in the chemical interface layer of Love wave sensors. | Love waves have been introduced as highly effective devices for liquid-sensing applications. For chemical sensors, a microacoustic delay line featuring a multilayered waveguide supporting a generalised Love wave mode can be used in an oscillator setup. The top layer of the waveguide is a chemical interface, which selec... | 10.1109/58.842058 | 18,238,598 | IEEE transactions on ultrasonics, ferroelectrics, and frequency control | 2,000 | ||
Multiple fibroadenomas in bilateral breasts of a 46-year-old Indian woman - A case report. | INTRODUCTION
Fibroadenomas are among the most common tumours of the female breast, occurring most frequently in women of child-bearing age, especially those under 30 years.
PRESENTATION OF CASE
We report a case with a total of 27 fibroadenomas presenting bilaterally of a 46-year-old woman. The histopathologic and imm... | 24,709,623 | International journal of surgery case reports | 2,014 | |||
Parent perspectives and reasons for lower urgency paediatric presentations to emergency departments. | OBJECTIVE
The age band with, by far, the greatest number of ED presentations is children 0-4 years, with other paediatric age bands also among the highest. As the majority of these presentations are for lower urgency conditions, we sought to determine why parents seek ED care for their child for lower urgency condition... | 10.1111/1742-6723.12544 | 26,879,127 | D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004636:Emergency Service, Hospital; D005194:Family Practice; D005260:Female; D006297:Health Services Accessibility; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010290:Parents; D010342:Patient Acceptance of Health Care; ... | Emergency medicine Australasia : EMA | 2,016 | |
Use of lignocellulose biomass for endoxylanase production by Streptomyces termitum. | Actinobacteria isolates from Brazilian Cerrado soil were evaluated for their ability to produce enzymes of the cellulolytic and xylanolytic complex using lignocellulose residual biomass. Preliminary semiquantitative tests, made in Petri plates containing carboxymethylcellulose and beechwood xylan, indicated 11 potentia... | 10.1080/10826068.2016.1275015 | 28,045,607 | D039903:Actinobacteria; D018533:Biomass; D002480:Cellulase; D002482:Cellulose; D043364:Endo-1,4-beta Xylanases; D007218:Industrial Microbiology; D008031:Lignin; D031786:Saccharum; D013302:Streptomyces; D014990:Xylans; D014995:Xylosidases | Preparative biochemistry & biotechnology | 2,017 | D014990:Xylans; C036909:lignocellulose; D002482:Cellulose; D008031:Lignin; C027433:bagasse; D014995:Xylosidases; C026579:exo-1,4-beta-D-xylosidase; D002480:Cellulase; D043364:Endo-1,4-beta Xylanases |
Allogeneic versus semiallogeneic F1 bone marrow transplantation into sublethally irradiated MHC-disparate hosts. Effects on mixed lymphoid chimerism, skin graft tolerance, host survival, and alloreactivity. | In models of tolerance associated with mixed lymphoid chimerism, depletion of Thy 1+ cells from the allogeneic donor inoculum may decrease the level of chimerism achieved and the capacity of donor cells to induce tolerance. To determine whether the apparent role of Thy 1+ cells in the facilitation of bone marrow engraf... | 10.1097/00007890-199001000-00031 | 2,137,269 | D000818:Animals; D016026:Bone Marrow Transplantation; D002678:Chimera; D006086:Graft vs Host Disease; D006183:H-2 Antigens; D007108:Immune Tolerance; D007959:Lymphocyte Culture Test, Mixed; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D016038:Skin Transplantation; D013601:T-Lymphocytes; D01418... | Transplantation | 1,990 | D006183:H-2 Antigens |
Calcium channels in the brain as targets for the calcium-channel modulators used in the treatment of neurological disorders. | Recent investigations of calcium channels in brain cells by voltage-clamp techniques have revealed that, in spite of electrophysiological similarities, the pharmacological properties of these channels differ considerably from channels in peripheral tissues, e.g., heart and smooth muscle. Therefore, instead of extrapola... | 1,726,728 | D000818:Animals; D001921:Brain; D002121:Calcium Channel Blockers; D015220:Calcium Channels; D009422:Nervous System Diseases; D009474:Neurons | Journal of cardiovascular pharmacology | 1,991 | D002121:Calcium Channel Blockers; D015220:Calcium Channels | |
Life-Course Approach to Vaccination in Bangladesh for Meeting the Health and Health-Related Sustainable Development Goals: A Commentary. | Bangladesh is entering from low-income to lower-middle-income status in 2020, and this will be completed in the next 5 years. With gross national income growing, vaccines will need to be procured through private market for the Expanded Program on Immunization. A cost-benefit analysis is needed to evaluate vaccine deman... | 10.1093/infdis/jiab455 | 34,549,784 | D001459:Bangladesh; D002771:Cholera; D022121:Cholera Vaccines; D021821:Communicable Diseases, Emerging; D006801:Humans; D017589:Immunization Programs; D000076502:Sustainable Development; D014611:Vaccination | The Journal of infectious diseases | 2,021 | D022121:Cholera Vaccines |
The proteoglycans of the human intervertebral disc. | The methods of Hascall & Sajdera (1969) were used to compare the proteoglycans of human intervertebral disc with those of bovine nasal cartilage. In contrast with cartilage, most of the hexuronate of disc could be extracted at low shear with water or dilute salt solutions. Extracts of disc with 4M-guanidinium chloride ... | 10.1042/bj1450549 | 125,582 | D000818:Animals; D002356:Cartilage; D002417:Cattle; D006025:Glycosaminoglycans; D006146:Guanidines; D006603:Hexuronic Acids; D006801:Humans; D007403:Intervertebral Disc; D008297:Male; D009666:Nose; D011509:Proteoglycans; D012995:Solubility | The Biochemical journal | 1,975 | D006025:Glycosaminoglycans; D006146:Guanidines; D006603:Hexuronic Acids; D011509:Proteoglycans |
Precision Medicine for Breath-Focused Mind-Body Therapies for Stress and Anxiety: Are We Ready Yet? | In this viewpoint, we present an argument for transdisciplinary "precision medicine" approaches that combine studies of basic neurobiology of breathing in animal and human models of stress that can help characterize physiological and neural biomarkers and mechanisms of breathing control and emotion regulation in humans... | 10.1177/2164956120986129 | 33,489,480 | Global advances in health and medicine | 2,021 | ||
Management of the marginal mandibular nerve during and after neck dissection. | PURPOSE OF REVIEW
Marginal mandibular nerve palsy (MMNP) is often an understated complication after neck dissection. This article reviews literature regarding anatomic landmarks that help define marginal mandibular nerve (MMN) during neck dissection, oncologic safety of surgical maneuvers, implications of MMNP, and rec... | 10.1097/MOO.0000000000000523 | 30,664,053 | D000465:Algorithms; D005154:Facial Nerve; D020220:Facial Nerve Injuries; D006258:Head and Neck Neoplasms; D006801:Humans; D008198:Lymph Nodes; D008207:Lymphatic Metastasis; D037981:Neck Dissection; D011788:Quality of Life | Current opinion in otolaryngology & head and neck surgery | 2,019 | |
Coccygectomy for refractory coccygodynia: a systematic review and meta-analysis. | PURPOSE
We sought to systematically assess and summarize the available literature on outcomes following coccygectomy for refractory coccygodynia.
METHODS
PubMed, Scopus, and Cochrane Library databases were systematically searched in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyse... | 10.1007/s00586-021-07041-6 | 34,694,498 | D003050:Coccyx; D005260:Female; D006801:Humans; D017116:Low Back Pain; D011446:Prospective Studies; D012189:Retrospective Studies; D016896:Treatment Outcome | European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society | 2,022 | |
Genetic diversity of Cylindrospermopsis strains (cyanobacteria) isolated from four continents. | The genetic diversity of Cylindrospermopsis strains (cyanobacteria) was examined using mainly the 16S-23S internally transcribed spacer (ITS1) sequences. Strains were grouped in three clusters: (i) America, (ii) Europe, and (iii) Africa and Australia. These results suggested a recent spread of Cylindrospermopsis across... | 10.1128/AEM.71.2.1097-1100.2005 | 15,691,973 | D000349:Africa; D000569:Americas; D001315:Australia; D001483:Base Sequence; D046891:Cylindrospermopsis; D021903:DNA, Ribosomal Spacer; D012321:DNA-Directed RNA Polymerases; D005060:Europe; D005618:Fresh Water; D014644:Genetic Variation; D008969:Molecular Sequence Data; D010088:Oxidoreductases; D012336:RNA, Ribosomal, 1... | Applied and environmental microbiology | 2,005 | D021903:DNA, Ribosomal Spacer; D012336:RNA, Ribosomal, 16S; D012338:RNA, Ribosomal, 23S; D010088:Oxidoreductases; C029130:nitrogenase reductase; C108570:beta' subunit of RNA polymerase; D012321:DNA-Directed RNA Polymerases |
Anthocyanin inheritance and instability in purple basil (Ocimum basilicum L.). | The instability of the purple pigments (anthocyanins) in purple basil varieties (Ocimum basilicum L.) limits their use as ornamental plants and as a potential anthocyanin source. Several self-pollinated generations of all purple plants were unsuccessful in stabilizing anthocyanin expression. In this study we investigat... | 10.1093/jhered/91.4.289 | 10,912,675 | D000872:Anthocyanins; D002851:Chromatography, High Pressure Liquid; D003433:Crosses, Genetic; D016296:Mutagenesis; D018649:Ocimum basilicum; D018515:Plant Leaves; D010938:Plant Oils | The Journal of heredity | 2,000 | D000872:Anthocyanins; D010938:Plant Oils |
Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice. | African Americans develop end-stage renal disease at a higher rate compared with European Americans due to 2 polymorphisms (G1 and G2 risk variants) in the apolipoprotein L1 (APOL1) gene common in people of African ancestry. Although this compelling genetic evidence provides an exciting opportunity for personalized med... | 31,217,349 | D000818:Animals; D000075944:Apolipoprotein L1; D002460:Cell Line; D005260:Female; D006801:Humans; D007371:Interferon-gamma; D051379:Mice; D008822:Mice, Transgenic; D016376:Oligonucleotides, Antisense; D011507:Proteinuria | JCI insight | 2,019 | C108666:APOL1 protein, human; D000075944:Apolipoprotein L1; D016376:Oligonucleotides, Antisense; D007371:Interferon-gamma | |
Automated QuEChERS for the determination of 482 pesticide residues in Radix codonopsis by GC-Q-TOF/MS and LC-Q-TOF/MS. | A rapid procedure for the determination of 482 pesticide residues in Chinese Materia Medica by GC-Q-TOF/MS and LC-Q-TOF/MS (379 pesticides for LC, 327 pesticides for GC, and 226 pesticides for both) was developed. Radix codonopsis was chosen as the matrix for verification, and a comparative study on the QuEChERS sample... | 10.1039/d1ay01616d | 34,788,351 | D002853:Chromatography, Liquid; D029745:Codonopsis; D008401:Gas Chromatography-Mass Spectrometry; D013058:Mass Spectrometry; D010573:Pesticide Residues | Analytical methods : advancing methods and applications | 2,021 | D010573:Pesticide Residues |
Preparation of Three-Dimensional Chitosan-Graphene Oxide Aerogel for Residue Oil Removal. | Graphene oxide has been used as an adsorbent in wastewater treatment. However, the hydrophily and dispersibility in aqueous solution limit its practical application in environmental protection. In this paper, a novel, environmentally friendly adsorbent, chitosan and chitosan-graphene oxide aerogels with a diverse shape... | 10.2175/106143016X14609975747207 | 27,456,137 | D000327:Adsorption; D048271:Chitosan; D005612:Freeze Drying; D005742:Gasoline; D006108:Graphite; D006863:Hydrogen-Ion Concentration; D012623:Seawater; D017550:Spectroscopy, Fourier Transform Infrared; D014874:Water Pollutants, Chemical | Water environment research : a research publication of the Water Environment Federation | 2,016 | D005742:Gasoline; D014874:Water Pollutants, Chemical; D006108:Graphite; D048271:Chitosan |
Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human. | BACKGROUND
Dilated cardiomyopathy (DCM) is a life-threatening heart disease and a common cause of heart failure due to systolic dysfunction and subsequent left or biventricular dilatation. A significant number of cases have a genetic etiology; however, as a complex disease, the exact genetic risk factors are largely un... | 10.1186/s13073-023-01221-3 | 37,723,491 | D006801:Humans; D000818:Animals; D004285:Dogs; D002311:Cardiomyopathy, Dilated; D006706:Homeostasis; D023421:Models, Animal; D010641:Phenotype; D012307:Risk Factors | Genome medicine | 2,023 | |
Send more data: a systematic review of mathematical models of antimicrobial resistance. | Background
Antimicrobial resistance is a global health problem that demands all possible means to control it. Mathematical modelling is a valuable tool for understanding the mechanisms of AMR development and spread, and can help us to investigate and propose novel control strategies. However, it is of vital importance ... | 10.1186/s13756-018-0406-1 | 30,288,257 | D000818:Animals; D000890:Anti-Infective Agents; D004352:Drug Resistance, Microbial; D006801:Humans; D008962:Models, Theoretical; D062486:Public Health Surveillance; D015203:Reproducibility of Results | Antimicrobial resistance and infection control | 2,018 | D000890:Anti-Infective Agents |
Face-Processing Performance is an Independent Predictor of Social Affect as Measured by the Autism Diagnostic Observation Schedule Across Large-Scale Datasets. | Face-processing deficits, while not required for the diagnosis of autism spectrum disorder (ASD), have been associated with impaired social skills-a core feature of ASD; however, the strength and prevalence of this relationship remains unclear. Across 445 participants from the NIMH Data Archive, we examined the relatio... | 10.1007/s10803-021-04971-4 | 33,743,118 | D000067877:Autism Spectrum Disorder; D001321:Autistic Disorder; D000066499:Facial Recognition; D006801:Humans; D021641:Recognition, Psychology; D066107:Social Skills | Journal of autism and developmental disorders | 2,022 | |
Localization of cytoskeletal proteins in Cryptosporidium parvum using double immunogold labeling. | Actin and some actin binding proteins such as tropomyosin, alpha-actinin and troponin T were localized by simultaneous double immunogold labeling in several developmental stages of Cryptosporidium parvum. All of the observed developmental stages have many particles of tropomyosin and actin around pellicle and cytoplasm... | 10.3347/kjp.1996.34.4.215 | 9,017,906 | D000185:Actinin; D000818:Animals; D016785:Cryptosporidium parvum; D007150:Immunohistochemistry; D051379:Mice; D008813:Mice, Inbred ICR; D008854:Microscopy, Electron; D014335:Tropomyosin; D014336:Troponin; D020107:Troponin T | The Korean journal of parasitology | 1,996 | D014335:Tropomyosin; D014336:Troponin; D020107:Troponin T; D000185:Actinin |
[Respiratory preparation before surgery in patients with chronic respiratory failure]. | Scheduled and/or thoracic, abdominal surgeries increase the risk of respiratory postoperative complications. In patients with chronic respiratory failure, preoperative evaluation should be performed to evaluate respiratory function in aim to optimize perioperative management. Preoperative gas exchange abnormalities (hy... | 10.1016/j.lpm.2011.08.007 | 22,004,791 | D000005:Abdomen; D000328:Adult; D000465:Algorithms; D000698:Analgesia; D000758:Anesthesia; D002908:Chronic Disease; D006801:Humans; D010149:Pain, Postoperative; D011013:Pneumonectomy; D011183:Postoperative Complications; D011300:Preoperative Care; D012131:Respiratory Insufficiency; D012138:Respiratory Therapy; D016540:... | Presse medicale (Paris, France : 1983) | 2,012 | |
Impact of type 1 diabetes mellitus and celiac disease on nutrition and quality of life. | OBJECTIVE
Type 1 diabetes mellitus (T1DM) and celiac disease (CD) are autoimmune diseases and have similar genetic patterns. T1DM treatment is based on diet, physical activity and insulin therapy, whereas CD depends on dietary changes with restriction of wheat, rye and barley. The aim of the study was to evaluate the q... | 10.1038/nutd.2016.43 | 28,067,892 | D000328:Adult; D001786:Blood Glucose; D015992:Body Mass Index; D002446:Celiac Disease; D003922:Diabetes Mellitus, Type 1; D055050:Diet, Gluten-Free; D005260:Female; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D009752:Nutritional Status; D010349:Patient Compliance; D010549:Personal Satisfac... | Nutrition & diabetes | 2,017 | D001786:Blood Glucose |
Clinical chemical indexes and severity of coronary atherosclerosis. | The present study measured triglycerides (TG), total cholesterol (TC), HDL-cholesterol (HDL-C), LDL and LDL/HDL-C, TC/HDL-C and HDL-C/TC. 100 ratios in 261 men and women undergoing coronary arteriography. The results show that TG, TC, HDL-C and LDL levels are not related to the severity of coronary artery disease (CAD)... | 10.1016/0009-8981(83)90302-9 | 6,872,262 | D000328:Adult; D000368:Aged; D002784:Cholesterol; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D003327:Coronary Disease; D005260:Female; D006801:Humans; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008297:Male; D008875:Middle Aged; D014280:Triglycerides | Clinica chimica acta; international journal of clinical chemistry | 1,983 | D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D014280:Triglycerides; D002784:Cholesterol |
(3,4-Dimeth-oxy-phen-yl)(4-fluoro-phen-yl)methanone. | In the title compound, C(15)H(13)FO(3), the dihedral angle between the two aromatic rings is 52.78 (8)°. In the crystal, inter-molecular C-H⋯O hydrogen bonds link mol-ecules into chains running parallel to the c axis. | 10.1107/S1600536810021008 | 21,587,825 | Acta crystallographica. Section E, Structure reports online | 2,010 | ||
Genome-Wide Identification and Expression Analyses of the Fibrillin Family Genes Suggest Their Involvement in Photoprotection in Cucumber. | Fibrillin (FBN) is a plastid lipid-associated protein found in photosynthetic organisms from cyanobacteria to plants. In this study, 10 CsaFBN genes were identified in genomic DNA sequences of cucumber (Chinese long and Gy14) through database searches using the conserved domain of FBN and the 14 FBN genes of Arabidopsi... | 10.3390/plants7030050 | 29,954,122 | Plants (Basel, Switzerland) | 2,018 | ||
Studies on cytotoxic and genotoxic effects of N-hydroxypyridine-2-thione (Omadine) in L5178Y mouse lymphoma cells. | The cytotoxicity and genotoxicity of the antifungal and antimicrobial agent Omadine, i.e. N-hydroxypyridine-2-thione (HOPT), has been investigated in L5178Y mouse lymphoma cells in the dark and under UVA irradiation. Omadine inhibits cell growth and induces micronuclei at concentrations >0.5 microM in the absence of li... | 10.1016/s0378-4274(02)00279-5 | 12,368,059 | D000818:Animals; D000890:Anti-Infective Agents; D002273:Carcinogens; D002455:Cell Division; D002462:Cell Membrane; D002470:Cell Survival; D003624:Darkness; D017484:Dermatitis, Phototoxic; D004950:Esterases; D005456:Fluorescent Dyes; D016166:Free Radical Scavengers; D005978:Glutathione; D017665:Hydroxyl Radical; D008223... | Toxicology letters | 2,002 | D000890:Anti-Infective Agents; D002273:Carcinogens; D005456:Fluorescent Dyes; D016166:Free Radical Scavengers; D009153:Mutagens; D011725:Pyridines; D013871:Thiones; D017665:Hydroxyl Radical; C008704:pyrithione; D004950:Esterases; D005978:Glutathione |
Influence of Dietary Sodium and Potassium Intake on the Heart Rate Corrected-QT Interval in Elderly Subjects. | It is well known that imbalances in the dietary electrolytes are associated with a significantly higher incidence of cardiovascular disease (CVD). On the other hand, a prolonged heart rate corrected-QT (QTc) interval is associated with an increased risk of cardiac autonomic nervous system dysfunction, the incidence of ... | 10.3177/jnsv.61.138 | 26,052,144 | D000368:Aged; D001145:Arrhythmias, Cardiac; D015992:Body Mass Index; D001835:Body Weight; D053840:Brugada Syndrome; D000075224:Cardiac Conduction System Disease; D002318:Cardiovascular Diseases; D004032:Diet; D004562:Electrocardiography; D004573:Electrolytes; D005247:Feeding Behavior; D005260:Female; D006321:Heart; D00... | Journal of nutritional science and vitaminology | 2,015 | D004573:Electrolytes; D012982:Sodium, Dietary; D011188:Potassium |
Comparative Analysis of Model-Based Predictive Shared Control for Delayed Operation in Object Reaching and Recognition Tasks With Tactile Sensing. | Communication delay represents a fundamental challenge in telerobotics: on one hand, it compromises the stability of teleoperated robots, on the other hand, it decreases the user's awareness of the designated task. In scientific literature, such a problem has been addressed both with statistical models and neural netwo... | 10.3389/frobt.2021.730946 | 34,738,017 | Frontiers in robotics and AI | 2,021 | ||
Percutaneous Coronary Intervention With Bioresorbable Scaffolds in a Young Child. | Importance
Although much less frequent than in adults, coronary artery disease requiring revascularization may develop in children because of homozygous familial hypercholesterolemia or other underlying conditions. Percutaneous coronary intervention (PCI) with a bioresorbable scaffold (BRS) may have advantages over met... | 10.1001/jamacardio.2016.4954 | 28,030,655 | D020341:Absorbable Implants; D002675:Child, Preschool; D003324:Coronary Artery Disease; D003331:Coronary Vessels; D006801:Humans; D008297:Male; D062645:Percutaneous Coronary Intervention; D054457:Tissue Scaffolds; D018084:Ultrasonography, Interventional | JAMA cardiology | 2,017 | |
Update on Inflammatory Biomarkers and Treatments in Ischemic Stroke. | After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly induce both beneficial and detrimental effects. In this narrative review, we updated evidence on the inflammatory pathways and mediators that are investigated as promising therapeutic targets. We searched for papers on PubMed and MED... | 27,898,011 | D000818:Animals; D001323:Autoantibodies; D015415:Biomarkers; D006801:Humans; D007249:Inflammation; D008954:Models, Biological; D009504:Neutrophils; D020521:Stroke | International journal of molecular sciences | 2,016 | D001323:Autoantibodies; D015415:Biomarkers | |
Endocan Measurement for Active Behçet Disease. | OBJECTIVES
This study aims to investigate the relationships between serum endocan, vascular endothelial growth factor (VEGF), and tumor necrosis factor-alpha (TNF-α) levels in active Behçet disease.
PATIENTS AND METHODS
Forty patients with active Behçet disease (24 males, 16 females; mean age 37.6±8.7 years; range 20... | 10.5606/ArchRheumatol.2017.6072 | 30,375,545 | Archives of rheumatology | 2,017 | ||
Prospective Single-Center Observational Study of the Allergenic Potential of Mercromina Film and Other Common Antiseptics in Patients With Contact Dermatitis. | INTRODUCTION
Although Mercromina Film and other topical antiseptics are widely used, they are not included in the standard series recommended by the Spanish Contact Dermatitis and Skin Allergy Research Group for testing suspected allergic contact dermatitis (ACD). Furthermore, no recent studies have investigated the al... | 10.1016/j.ad.2017.06.013 | 28,969,846 | D000891:Anti-Infective Agents, Local; D002710:Chlorhexidine; D017449:Dermatitis, Allergic Contact; D003875:Drug Eruptions; D004801:Eosine Yellowish-(YS); D006801:Humans; D008622:Merbromin; D010328:Patch Tests; D011206:Povidone-Iodine; D011446:Prospective Studies; D013849:Thimerosal | Actas dermo-sifiliograficas | 2,018 | D000891:Anti-Infective Agents, Local; D013849:Thimerosal; D011206:Povidone-Iodine; D008622:Merbromin; C010882:chlorhexidine gluconate; D002710:Chlorhexidine; D004801:Eosine Yellowish-(YS) |
Bronchoscopic Lung Volume Reduction in Patients with Emphysema due to Alpha-1 Antitrypsin Deficiency. | BACKGROUND
Bronchoscopic lung volume reduction using one-way endobronchial valves (EBVs) is a valid therapy for severe emphysema patients. However, alpha-1 antitrypsin (AAT)-deficient patients were excluded from the majority of clinical trials investigating this intervention.
OBJECTIVES
The aim of this study was to i... | 10.1159/000528182 | 36,549,279 | D006801:Humans; D011013:Pneumonectomy; D012189:Retrospective Studies; D011788:Quality of Life; D011656:Pulmonary Emphysema; D019896:alpha 1-Antitrypsin Deficiency; D000515:alpha 1-Antitrypsin; D029424:Pulmonary Disease, Chronic Obstructive | Respiration; international review of thoracic diseases | 2,023 | D000515:alpha 1-Antitrypsin |
Analysis of the binding of hydroxamic acid and carboxylic acid inhibitors to the stromelysin-1 (matrix metalloproteinase-3) catalytic domain by isothermal titration calorimetry. | Matrix metalloproteinases (MMPs) are implicated in diseases such as arthritis and cancer. Among these enzymes, stromelysin-1 can also activate the proenzymes of other MMPs, making it an attractive target for pharmaceutical design. Isothermal titration calorimetry (ITC) was used to analyze the binding of three inhibitor... | 10.1021/bi991222g | 10,521,266 | D001665:Binding Sites; D002151:Calorimetry; D002264:Carboxylic Acids; D020134:Catalytic Domain; D004151:Dipeptides; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006877:Hydroxamic Acids; D046911:Macromolecular Substances; D019278:Matrix Metalloproteinase 3; D061965:Matrix Metalloproteinase Inhibitors; D009842:Ol... | Biochemistry | 1,999 | D002264:Carboxylic Acids; D004151:Dipeptides; D006877:Hydroxamic Acids; D046911:Macromolecular Substances; D061965:Matrix Metalloproteinase Inhibitors; C078131:N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide; D009842:Oligopeptides; D011480:Protease Inhibitors; D011522:Protons; D019278:... |
Antimicrobial susceptibilities of Erysipelothrix rhusiopathiae. | The in vitro susceptibilities of 10 isolates of Erysipelothrix rhusiopathiae to 16 antimicrobial agents were determined. Penicillin and imipenem were the most active agents, followed by piperacillin, cefotaxime, ciprofloxacin, pefloxacin, and clindamycin. Some resistance was observed with erythromycin, tetracycline, an... | 10.1128/AAC.34.10.2038 | 2,291,674 | D000900:Anti-Bacterial Agents; D004888:Erysipelothrix; D008826:Microbial Sensitivity Tests | Antimicrobial agents and chemotherapy | 1,990 | D000900:Anti-Bacterial Agents |
T-DNA tagging of a pathogen inducible promoter in Arabidopsis thaliana. | Summary Many events associated with the plant defence responses are regulated on the transcriptional level. Here we report the results of a promoter tagging approach to identify promoters that are induced upon pathogen attack in Arabidopsis thaliana. A line was identified in a T-DNA UidA tagged Arabidopsis library with... | 10.1046/j.1364-3703.2002.00115.x | 20,569,331 | Molecular plant pathology | 2,002 | ||
[Histological evaluation of biomaterials administration in vivo on the cartilage, bone and skin healing]. | Our aim was to show the benefits and limitations of histological assessment of healing supported by implantable biomaterials. We reviewed and showed photographs of the histological and immunohistochemical methods applicable for the assessment of desirable and undesirable effects of biomaterials on the healing of hard a... | 26,311,025 | D000818:Animals; D001672:Biocompatible Materials; D001842:Bone and Bones; D002356:Cartilage; D006801:Humans; D007150:Immunohistochemistry; D008422:Materials Testing; D012867:Skin; D014945:Wound Healing | Casopis lekaru ceskych | 2,015 | D001672:Biocompatible Materials | |
Early Change in Urine Protein as a Surrogate End Point in Studies of IgA Nephropathy: An Individual-Patient Meta-analysis. | BACKGROUND
The role of change in proteinuria as a surrogate end point for randomized trials in immunoglobulin A nephropathy (IgAN) has previously not been thoroughly evaluated.
STUDY DESIGN
Individual patient-level meta-analysis.
SETTING & POPULATION
Individual-patient data for 830 patients from 11 randomized trial... | 27,032,886 | D015415:Biomarkers; D018450:Disease Progression; D005922:Glomerulonephritis, IGA; D006801:Humans; D011507:Proteinuria; D016032:Randomized Controlled Trials as Topic; D013997:Time Factors | American journal of kidney diseases : the official journal of the National Kidney Foundation | 2,016 | D015415:Biomarkers | |
Potential use of Methylibium sp. as a biodegradation tool in organosilicon and volatile compounds removal for biogas upgrading. | Organosilicon compounds are the most undesirable compounds for the energy recovery of biogas. These compounds are still resistant to biodegradation when biotechnologies are considered for biogas purification. Herein we isolated 52 bacterial species from anaerobic batch enrichment cultures (BEC) saturated with D4 and fr... | 10.1016/j.chemosphere.2019.124908 | 31,726,596 | D000693:Anaerobiosis; D001673:Biodegradation, Environmental; D056804:Biofuels; D019149:Bioreactors; D000073556:Burkholderiales; D017646:Organosilicon Compounds; D055549:Volatile Organic Compounds; D018508:Water Purification | Chemosphere | 2,020 | D056804:Biofuels; D017646:Organosilicon Compounds; D055549:Volatile Organic Compounds |
Large Heterogeneity Among Minimal Clinically Important Differences for Hip Arthroscopy Outcomes: A Systematic Review of Reporting Trends and Quantification Methods. | PURPOSE
To perform a systematic review of reporting trends and quantification methods for the minimal clinically important difference (MCID) within the hip arthroscopy literature.
METHODS
Cochrane, PubMed, and OVID/MEDLINE databases were queried for hip arthroscopy articles that reported the MCID. Studies were classi... | 10.1016/j.arthro.2020.10.050 | 33,186,696 | D000203:Activities of Daily Living; D001182:Arthroscopy; D057925:Femoracetabular Impingement; D006615:Hip; D006621:Hip Joint; D006801:Humans; D000071081:Minimal Clinically Important Difference; D000071066:Patient Reported Outcome Measures; D013177:Sports; D016896:Treatment Outcome | Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association | 2,021 | |
Urban water and food security in this century and beyond: Resource-smart cities and residents. | The urban world population will increase from 3 to 8.5 thousand million in the 21st century. Cities become hot spots of both demand for water and global food and for disposed used water and nutrients. Sustainability requires that resource flows through our cities are co-managed and connected to agriculture. Reduced use... | 10.1007/s13280-020-01373-1 | 33,001,342 | D000383:Agriculture; D002947:Cities; D000082302:Food Security; D059027:Recycling; D014867:Water | Ambio | 2,021 | D014867:Water |
Automatic quiet sleep detection based on multifractality in preterm neonates: Effects of maturation. | This study investigates the multifractal formalism framework for quiet sleep detection in preterm babies. EEG recordings from 25 healthy preterm infants were used in order to evaluate the performance of multifractal measures for the detection of quiet sleep. Results indicate that multifractal analysis based on wavelet ... | 10.1109/EMBC.2017.8037246 | 29,060,290 | D001686:Biological Phenomena; D004569:Electroencephalography; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D012890:Sleep | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 2,017 | |
Bioactive secondary metabolites from marine Actinomyces sp. AW6 with an evaluation of ADME-related physicochemical properties. | This study was designed to evaluate the antimicrobial, antioxidant, and cytotoxic potentials of the marine actinomycetes spp. isolated from the Red Sea water, Hurghada, Egypt. Out of 80 actinomycetes isolates, one isolate AW6 was selected based on its antioxidant activity (IC50 about 5.24 µg/mL which scavenged 91% of f... | 10.1007/s00203-022-03092-5 | 35,913,539 | D000190:Actinomyces; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000975:Antioxidants; D002176:Candida albicans; D004926:Escherichia coli; D011550:Pseudomonas aeruginosa; D013211:Staphylococcus aureus | Archives of microbiology | 2,022 | D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000975:Antioxidants |
Leishmaniasis in South West Africa/Namibia to date. | A total of 34 patients with cutaneous leishmaniasis (CL) have been diagnosed in South West Africa/Namibia since 1970. Visceral leishmaniasis has not occurred. So far a sandfly Phlebotomus rossi has emerged as a possible vector of the disease in man. Several aspects of vector incrimination and bionomics still need clari... | 2,648,612 | D000293:Adolescent; D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004197:Disease Reservoirs; D005260:Female; D006801:Humans; D007043:Hyraxes; D007303:Insect Vectors; D007891:Leishmania; D007896:Leishmaniasis; D007898:Leishmaniasis, Visceral; D008297:Male; D008875:Middle Aged; D009276:Namibia... | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde | 1,989 | ||
Extracorporeal shock wave therapy in early osteonecrosis of the femoral head: prospective clinical study with long-term follow-up. | INTRODUCTION
Extracorporeal shock wave therapy (ESWT) may exert beneficial effects in avascular necrosis of femoral head (AVNFH).
PATIENTS
The current study evaluated the effectiveness of ESWT in reducing pain and in slowing down the progression of bone damage in 36 patients with unilateral AVNFH of stage Association... | 10.1007/s00402-011-1444-9 | 22,228,278 | D000328:Adult; D000368:Aged; D018771:Arthralgia; D005260:Female; D005271:Femur Head Necrosis; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011446:Prospective Studies; D016059:Range of Motion, Articular; D016896:Treatment Outcome; D059708:Ultrasonic Surgical Pr... | Archives of orthopaedic and trauma surgery | 2,012 | |
Childhood deaths and cargo barriers in cars. | To analyse features of childhood deaths associated with the absence or presence of car cargo barriers, three cases were taken from the files of the Department of Histopathology at the Women's and Children's Hospital and State Forensic Science Centre, Adelaide, Australia, over a 5-year period from January 1993 to Decemb... | 10.1046/j.1440-1754.1999.00379.x | 10,457,305 | D000063:Accidents, Traffic; D001336:Automobiles; D002648:Child; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007035:Hypothermia; D008297:Male; D011482:Protective Devices; D013021:South Australia | Journal of paediatrics and child health | 1,999 | |
Linking geological and health sciences to assess childhood lead poisoning from artisanal gold mining in Nigeria. | BACKGROUND
In 2010, Médecins Sans Frontières discovered a lead poisoning outbreak linked to artisanal gold processing in northwestern Nigeria. The outbreak has killed approximately 400 young children and affected thousands more.
OBJECTIVES
Our aim was to undertake an interdisciplinary geological- and health-science a... | 10.1289/ehp.1206051 | 23,524,139 | D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure; D014943:Global Health; D006046:Gold; D006801:Humans; D007855:Lead Poisoning; D008670:Metals; D008906:Mining; D009549:Nigeria; D010316:Particle Size | Environmental health perspectives | 2,013 | D008670:Metals; D006046:Gold |
Decoding speech from spike-based neural population recordings in secondary auditory cortex of non-human primates. | Direct electronic communication with sensory areas of the neocortex is a challenging ambition for brain-computer interfaces. Here, we report the first successful neural decoding of English words with high intelligibility from intracortical spike-based neural population activity recorded from the secondary auditory cort... | 10.1038/s42003-019-0707-9 | 31,840,111 | D000161:Acoustic Stimulation; D000465:Algorithms; D000818:Animals; D001303:Auditory Cortex; D001931:Brain Mapping; D055724:Electrophysiological Phenomena; D008962:Models, Theoretical; D009474:Neurons; D011323:Primates; D013060:Speech | Communications biology | 2,019 | |
Complete Genome Sequence of Psychrobacter alimentarius PAMC 27889, a Psychrophile Isolated from an Antarctic Rock Sample. | Psychrobacter alimentarius PAMC 27889, a Gram-negative, psychrophilic bacterium, was isolated from an Antarctic rock sample. Here, we report the complete genome of P. alimentarius PAMC 27889, which has the nonmevalonate methylerythritol phosphate pathway of terpenoid biosynthesis and a complete gene cluster for benzoat... | 27,445,386 | Genome announcements | 2,016 | |||
Examining labelling effects within discrete choice experiments: an application to recreational site choice. | Data from a discrete choice experiment aimed at eliciting the demand for recreational walking trails on farmland in Ireland is used to explore whether some respondents reach their choices solely on the basis of the alternative's label. To investigate this, this paper exploits a discrete mixtures approach that also enco... | 23,648,268 | D002755:Choice Behavior; D007494:Ireland; D008962:Models, Theoretical; D011998:Recreation; D012424:Rural Population | Journal of environmental management | 2,013 | ||
COVID-19 and medical education: an opportunity to build back better. | The coronavirus disease 2019 (COVID-19) outbreak in the Hubei province of China has rapidly transformed into a global pandemic. In response to the first few reported cases of COVID-19, the government of Ghana implemented comprehensive social and public health interventions aimed at containing the disease, albeit its ef... | 10.4314/gmj.v54i4s.18 | 33,976,451 | D000086382:COVID-19; D003479:Curriculum; D020375:Education, Distance; D004501:Education, Medical; D004522:Educational Status; D005544:Forecasting; D005869:Ghana; D006801:Humans; D000086402:SARS-CoV-2; D013337:Students, Medical | Ghana medical journal | 2,020 | |
A phase I pharmacokinetic and pharmacodynamic study of BGC9331 and carboplatin in relapsed gynaecological malignancies. | BGC9331 is a rationally designed, specific nonpolyglutamatable thymidylate synthase (TS) inhibitor that is active in gynaecological malignancies. In the light of the sensitivity of human ovarian tumour cell lines to BGC9331 and non-cross resistance to platinum drugs, we studied the combination BGC9331/carboplatin (BCA)... | 10.1038/sj.bjc.6602811 | 16,222,320 | D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D019540:Area Under Curve; D016190:Carboplatin; D004791:Enzyme Inhibitors; D005260:Female; D005833:Genital Neoplasms, Female; D006801:Humans; D007262:Infusions, Intravenous; D020714:Maximum Tolerated Dose; D008875:Middle Aged; D009503:Neutropenia; D0... | British journal of cancer | 2,005 | D004791:Enzyme Inhibitors; D016190:Carboplatin; D013940:Thymidylate Synthase |
Intensive blood pressure lowering: a practical review. | According to the last Hypertension guideline recommendations, it may be concluded that intensive BP lowering is only advisable in a subgroup of patients where there is a clear net benefit of targeting to lower BP goals. However, taking into account the relevance of correct BP measurement, estimates of the benefits vers... | 10.1186/s40885-020-00153-z | 33,292,735 | Clinical hypertension | 2,020 | ||
Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: Indications, Technical Aspects, and Clinical Outcomes. | Hypertrophic cardiomyopathy is the most common genetically transmitted heart disease. Around two-thirds of patients develop symptoms caused by the dynamic left ventricular outflow tract obstruction, either at rest or during effort. For patients with hypertrophic obstructive cardiomyopathy (HOCM) that remain symptomatic... | 29,207,362 | D055011:Ablation Techniques; D002312:Cardiomyopathy, Hypertrophic; D003935:Diagnostic Techniques, Cardiovascular; D000431:Ethanol; D006346:Heart Septum; D006801:Humans; D012597:Sclerosing Solutions; D016896:Treatment Outcome | The Journal of invasive cardiology | 2,017 | D012597:Sclerosing Solutions; D000431:Ethanol | |
A 5 GHz and 7.5 V multi-amplitude modulator driving circuit for practical high-speed quantum key distribution. | Quantum key distribution (QKD) offers the ability of information theoretic security key exchange. The secure key rate is an important indicator for the practical QKD systems, which determines what kinds of applications can be supported. One most effective way to enhance the secure key rate is to increase the system rep... | 10.1063/1.5140695 | 32,113,405 | The Review of scientific instruments | 2,020 | ||
Chemokine Regulation in Temporomandibular Joint Disease: A Comprehensive Review. | Temporomandibular joint disorders (TMDs) are conditions that affect the muscles of mastication and joints that connect the mandible to the base of the skull. Although TMJ disorders are associated with symptoms, the causes are not well proven. Chemokines play an important role in the pathogenesis of TMJ disease by promo... | 10.3390/genes14020408 | 36,833,336 | D006801:Humans; D013705:Temporomandibular Joint Disorders; D010003:Osteoarthritis; D013583:Synovial Membrane; D014409:Tumor Necrosis Factor-alpha | Genes | 2,023 | D014409:Tumor Necrosis Factor-alpha |
[Effect of butyl alcohol extract of Baitouweng Decoction on epithelial barrier of vaginal mucosa in mice with vulvovaginal candidiasis]. | To investigate the effect of butyl alcohol extract of Baitouweng Decoction(BAEB) on the epithelial barrier of vaginal mucosa in mice with vulvovaginal candidiasis(VVC). Seventy-two female SPF Kunming mice were randomly divided into blank group, VVC model group, fluconazole group, and BAEB treatment groups(high, middle ... | 10.19540/j.cnki.cjcmm.20200618.401 | 33,350,274 | D020001:1-Butanol; D000818:Animals; D000935:Antifungal Agents; D002176:Candida albicans; D002181:Candidiasis, Vulvovaginal; D005260:Female; D006801:Humans; D051379:Mice; D009092:Mucous Membrane; D014621:Vagina | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | 2,020 | D000935:Antifungal Agents; D020001:1-Butanol |
The protein shuffle. Sequential interactions among components of the human nucleotide excision repair pathway. | Xeroderma pigmentosum (XP) is an inherited disease in which cells from patients exhibit defects in nucleotide excision repair (NER). XP proteins A-G are crucial in the processes of DNA damage recognition and incision, and patients with XP can carry mutations in any of the genes that specify these proteins. In mammalian... | 10.1111/j.1742-4658.2006.05189.x | 16,623,697 | D004249:DNA Damage; D004260:DNA Repair; D004268:DNA-Binding Proteins; D006801:Humans; D011485:Protein Binding; D015398:Signal Transduction | The FEBS journal | 2,006 | D004268:DNA-Binding Proteins |
The biological and clinical significance of the KI-67 growth fraction in multiple myeloma. | We tested the significance of the Ki-67 plasma cell growth fraction in 49 bone marrow samples from 42 patients with multiple myeloma (MM). As a new approach to study myeloma cell proliferation, strong positivity of the CD38 antigen as plasma cell related feature was simultaneously evaluated with nuclear Ki-67 expressio... | 10.1002/hon.2900100209 | 1,592,363 | D002455:Cell Division; D004273:DNA, Neoplasm; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D019394:Ki-67 Antigen; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma; D009367:Neoplasm Staging; D009687:Nuclear Proteins; D011379:Prognosis; D012008:Recurrence | Hematological oncology | 1,992 | D004273:DNA, Neoplasm; D019394:Ki-67 Antigen; D009687:Nuclear Proteins |
Atmospheric pressure effects on the calibration constant of alpha-track radon detectors. | Accurate determination of the calibration constant is essential for the reliable determination of indoor radon air concentrations using alpha-track detectors. One possible source of error in the application of this method of radon assay is an effect of air density on the calibration factor. Such an effect, if present, ... | 10.1097/00004032-199403000-00013 | 8,106,252 | D000512:Alpha Particles; D001274:Atmospheric Pressure; D002138:Calibration; D011874:Radiometry; D011886:Radon | Health physics | 1,994 | D011886:Radon |
Deep hypothermic circulatory arrest versus non-deep hypothermic beating heart strategy in descending thoracic or thoracoabdominal aortic surgery. | OBJECTIVES
The ideal cardiopulmonary bypass (CPB) strategy during open surgical repair of the descending thoracic aorta (DTA) or thoracoabdominal aorta (TAA) is controversial. This study aimed to compare the clinical outcomes between deep hypothermic circulatory arrest (DHCA) and non-deep hypothermic beating heart CPB ... | 10.1093/ejcts/ezu053 | 24,578,408 | D000328:Adult; D000368:Aged; D001013:Aorta, Thoracic; D017545:Aortic Aneurysm, Thoracic; D050792:Circulatory Arrest, Deep Hypothermia Induced; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery | 2,014 | |
Orientation Inside Linear Nests by Male and Female Osmia bicornis (Megachilidae). | Numerous species of solitary bees and wasps build linear nests with only one entrance. Developing insects must orient themselves inside their nest to choose the correct direction in which to emerge. Misorientation and chewing towards the dead end of the nest can result in significant mortality. Most insects position th... | 10.1093/jisesa/iex010 | 28,355,480 | D000818:Animals; D001516:Bees; D005260:Female; D008297:Male; D009425:Nesting Behavior; D000072458:Orientation, Spatial | Journal of insect science (Online) | 2,017 | |
HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways. | Ischemic stroke is a clinically common cerebrovascular disease whose main risks include necrosis, apoptosis and cerebral infarction, all caused by cerebral ischemia and reperfusion (I/R) injury. This process has particular significance for the treatment of stroke patients. Notoginseng leaf triterpenes (PNGL), as a valu... | 10.3390/biom9100512 | 31,547,018 | D000818:Animals; D017209:Apoptosis; D001812:Blood-Brain Barrier; D020520:Brain Infarction; D016207:Cytokines; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D005786:Gene Expression Regulation; D024243:HMGB1 Protein; D020244:Infarction, Middle Cerebral Artery; D008297:Male; D020928:Mitogen-Act... | Biomolecules | 2,019 | D016207:Cytokines; D024243:HMGB1 Protein; C104200:Hbp1 protein, rat; D016328:NF-kappa B; D014315:Triterpenes; D020928:Mitogen-Activated Protein Kinases |
[Pancreatic lithogenesis]. | The first lesion of chronic calcifying pancreatitis (CCP), the most frequent form of chronic pancreatitis is the formation in the ducts of plugs build up of protein and calcium carbonate which are at the origin of pancreatic calculi. Pancreatic juice is supersaturated in calcium carbonate. A novel protein, the pancreat... | 3,963,739 | D002135:Calcium-Binding Proteins; D002137:Calculi; D002908:Chronic Disease; D006801:Humans; D051847:Lithostathine; D009419:Nerve Tissue Proteins; D010179:Pancreas; D010189:Pancreatic Juice; D010195:Pancreatitis | Annales de gastroenterologie et d'hepatologie | 1,986 | D002135:Calcium-Binding Proteins; D051847:Lithostathine; D009419:Nerve Tissue Proteins; C497617:REG1A protein, human | |
Quantifying Non-Stationarity with Information Theory. | We introduce an index based on information theory to quantify the stationarity of a stochastic process. The index compares on the one hand the information contained in the increment at the time scale τ of the process at time t with, on the other hand, the extra information in the variable at time t that is not present ... | 10.3390/e23121609 | 34,945,915 | Entropy (Basel, Switzerland) | 2,021 | ||
Protective effects of nimodipine and lithium against aluminum-induced cell death and oxidative stress in PC12 cells. | OBJECTIVES
The role of aluminum (Al) in the pathogenesis of neurodegenerative diseases has been implicated in several studies. However, the exact mechanisms of cytotoxic effects of Al have not been elucidated yet. The aim of this study was to investigate the effect of L-type calcium channel antagonist, nimodipine (NM),... | 27,917,283 | Iranian journal of basic medical sciences | 2,016 | |||
Antigen-induced aggregation and modulation of receptors on hapten-specific B lymphocytes. | Mouse spleen cells were subjected to a fractionation procedure designed to enrich for 4-hydroxy-3-iodo-5-nitro-phenylacetyl (NIP)- or DNP-specific B lymphocytes, which depended on adherence of specific cells to a layer of hapten-gelatin at 4 degrees C, recovery of bound cells by melting, and digestion of adherent antig... | 10.1084/jem.143.3.511 | 55,458 | D000818:Animals; D000917:Antibody Formation; D001402:B-Lymphocytes; D001666:Binding Sites, Antibody; D002458:Cell Fractionation; D002462:Cell Membrane; D004140:Dinitrophenols; D004705:Endocytosis; D000939:Epitopes; D005408:Flagellin; D006241:Haptens; D007104:Immune Adherence Reaction; D007108:Immune Tolerance; D051379:... | The Journal of experimental medicine | 1,976 | D004140:Dinitrophenols; D000939:Epitopes; D006241:Haptens; D005408:Flagellin; D009592:Nitrohydroxyiodophenylacetate |
Minimizing Thermal Damage During Thulium Laser-Assisted Partial Arytenoidectomy: Pulsed Versus Continuous Cutting in an Ex-Vivo Calf Model. | OBJECTIVES
The 2 µm-wavelength thulium laser is an effective cutter during partial arytenoidectomy, but thermal trauma can damage adjacent laryngeal tissue. Pulsing laser energy may reduce trauma when compared to continuous-wave cutting. This study measured temperature changes, thermal trauma, and time to complete part... | 10.1177/00034894231157648 | 36,824,026 | D006801:Humans; D013932:Thulium; D053685:Laser Therapy; D007830:Larynx; D014827:Vocal Cords; D007834:Lasers | The Annals of otology, rhinology, and laryngology | 2,023 | D013932:Thulium |
MRI-based age prediction using hidden Markov models. | Cortical thinning and intracortical gray matter volume losses are widely observed in normal ageing, while the decreasing rate of the volume loss in subjects with neurodegenerative disorders such as Alzheimer's disease is reported to be faster than the average speed. Therefore, neurodegenerative disease is considered as... | 10.1016/j.jneumeth.2011.04.022 | 21,549,147 | D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D000544:Alzheimer Disease; D000886:Anthropometry; D001284:Atrophy; D001921:Brain; D002540:Cerebral Cortex; D002555:Cerebrospinal Fluid; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D00829... | Journal of neuroscience methods | 2,011 | |
Prevalence, Magnitude, and Correlates of HIV-1 Genital Shedding in Women on Antiretroviral Therapy. | Background
Genital human immunodeficiency virus (HIV) RNA shedding can continue despite HIV being undetectable in blood, and can be associated with transmission.
Methods
We included African women on antiretroviral therapy (ART). Linear and generalized linear mixed models were used to compare the magnitude and prevale... | 10.1093/infdis/jix550 | 29,240,922 | D000328:Adult; D000349:Africa; D044966:Anti-Retroviral Agents; D001769:Blood; D005260:Female; D005836:Genitalia, Female; D015658:HIV Infections; D015497:HIV-1; D006801:Humans; D015995:Prevalence; D011446:Prospective Studies; D019562:Viral Load; D017201:Virus Shedding | The Journal of infectious diseases | 2,017 | D044966:Anti-Retroviral Agents |
Item analysis for the written test of Taiwanese board certification examination in anaesthesiology using the Rasch model. | BACKGROUND
On the written test of board certification examination for anaesthesiology, the probability of a question being answered correctly is subject to two main factors, item difficulty and examinee ability. Thus, item analysis can provide insight into the appropriateness of a particular test, given the ability of ... | 10.1093/bja/aeq097 | 20,427,368 | D000328:Adult; D000776:Anesthesiology; D002983:Clinical Competence; D004503:Education, Medical, Graduate; D004521:Educational Measurement; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D011594:Psychometrics; D015203:Reproducibility of Results; D013624:Taiwan | British journal of anaesthesia | 2,010 | |
Effects of object size on intralimb and interlimb coordination during a bimanual prehension task in patients with left cerebral vascular accidents. | Stroke patients are often left with hemiplegia or hemiparesis of the upper extremities, severely limiting the ability to perform bimanual and functional activities. No studies have investigated how stroke patients adapt their movements to changes in object size in functionally asymmetric bimanual tasks. The influence o... | 10.1123/mcj.12.4.296 | 18,955,740 | D001259:Ataxia; D002545:Brain Ischemia; D005260:Female; D018737:Hand Strength; D006801:Humans; D008297:Male; D008875:Middle Aged; D011597:Psychomotor Performance; D012720:Severity of Illness Index | Motor control | 2,008 | |
Development of a photosynthesis model with an emphasis on ecological applications : III. Carbon dioxide and oxygen dependencies. | A theoretical description of the simultaneous processes of photosynthesis and photorespiration in a single leaf is developed, based on the hypothesis that carbon dioxide and oxygen compete for the active site of ribulose diphosphate carboxylase. Michaelis-Menten kinetics and competitive inhibition at the end of a diffu... | 10.1007/BF01833627 | 28,309,341 | Oecologia | 1,977 | ||
Challenges of Capacity and Development for Health System Sustainability. | To achieve sustainability, remote and rural communities require health service models that are designed in and for these settings and are responsive to local population health needs. This paper draws on a panel discussion at the Rural and Indigenous Health Symposium held in Toronto, ON, on September 21, 2017. Active co... | 10.12927/hcpap.2018.25505 | 30,052,182 | D057191:Capacity Building; D018672:Community Health Planning; D003299:Cooperative Behavior; D006303:Health Services, Indigenous; D006280:Health Workforce; D006801:Humans; D009864:Ontario; D009937:Organizational Objectives; D012423:Rural Health | HealthcarePapers | 2,018 | |
Copper-Based Nanoscale Coordination Polymers Augmented Tumor Radioimmunotherapy for Immunogenic Cell Death Induction and T-Cell Infiltration. | Insufficient T-cell infiltration seriously hinders the efficacy of tumor immunotherapy. Induction of immunogenic cell death (ICD) is a potentially feasible approach to increase T-cell infiltration. Since ionizing radiation can only induce low-level ICD, this study constructs Cu-based nanoscale coordination polymers (Cu... | 10.1002/smll.202006231 | 33,522,120 | D045744:Cell Line, Tumor; D003300:Copper; D006801:Humans; D000079527:Immunogenic Cell Death; D007167:Immunotherapy; D009369:Neoplasms; D011108:Polymers; D016499:Radioimmunotherapy; D013601:T-Lymphocytes | Small (Weinheim an der Bergstrasse, Germany) | 2,021 | D011108:Polymers; D003300:Copper |
Acute hypoglycemic effect and phytochemical composition of Ageratina petiolaris. | ETHNOPHARMACOLOGICAL RELEVANCE
Type 2 diabetes is characterized by tissue resistance to the action of insulin combined with a relative deficiency in insulin secretion. In Mexico, medicinal plants have traditionally been used to control the disease; in this work, we investigate the hypoglycemic effect of Ageratina petio... | 27,013,093 | D036603:Ageratina; D000818:Animals; D001786:Blood Glucose; D003921:Diabetes Mellitus, Experimental; D005951:Glucose Tolerance Test; D005905:Glyburide; D007004:Hypoglycemic Agents; D064209:Phytochemicals; D008517:Phytotherapy; D010936:Plant Extracts; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors | Journal of ethnopharmacology | 2,016 | D001786:Blood Glucose; D007004:Hypoglycemic Agents; D064209:Phytochemicals; D010936:Plant Extracts; D005905:Glyburide | |
A novel approach to fabricate silk nanofibers containing hydroxyapatite nanoparticles using a three-way stopcock connector. | Electrospinning technique is commonly used to produce micro- and/or nanofibers, which utilizes electrical forces to produce polymeric fibers with diameters ranging from several micrometers down to few nanometers. Desirably, electrospun materials provide highly porous structure and appropriate pore size for initial cell... | 10.1186/1556-276X-8-303 | 23,816,050 | Nanoscale research letters | 2,013 | ||
When overexpressed, a novel centrosomal protein, RanBPM, causes ectopic microtubule nucleation similar to gamma-tubulin. | A novel human protein with a molecular mass of 55 kD, designated RanBPM, was isolated with the two-hybrid method using Ran as a bait. Mouse and hamster RanBPM possessed a polypeptide identical to the human one. Furthermore, Saccharomyces cerevisiae was found to have a gene, YGL227w, the COOH-terminal half of which is 3... | 10.1083/jcb.143.4.1041 | 9,817,760 | D048868:Adaptor Proteins, Signal Transducing; D000595:Amino Acid Sequence; D000818:Animals; D016466:CHO Cells; D019556:COS Cells; D018385:Centrosome; D006224:Cricetinae; D003598:Cytoskeletal Proteins; D018076:DNA, Complementary; D019143:Evolution, Molecular; D019204:GTP-Binding Proteins; D015870:Gene Expression; D01624... | The Journal of cell biology | 1,998 | D048868:Adaptor Proteins, Signal Transducing; D003598:Cytoskeletal Proteins; D018076:DNA, Complementary; D009687:Nuclear Proteins; C116005:Ran binding protein 9; D014404:Tubulin; D016244:Guanosine 5'-O-(3-Thiotriphosphate); D019204:GTP-Binding Proteins; D020931:ran GTP-Binding Protein |
FetA Antibodies Induced by an Outer Membrane Vesicle Vaccine Derived from a Serogroup B Meningococcal Isolate with Constitutive FetA Expression. | Invasive meningococcal disease causes over 3500 cases each year in Europe, with particularly high incidence among young children. Among serogroup B meningococci, which cause most of the cases, high diversity in the outer membrane proteins (OMPs) is observed in endemic situations; however, comprehensive molecular epidem... | 10.1371/journal.pone.0140345 | 26,466,091 | D000818:Animals; D001425:Bacterial Outer Membrane Proteins; D004195:Disease Models, Animal; D015870:Gene Expression; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D007114:Immunization; D008585:Meningitis, Meningococcal; D022401:Meningococcal Vaccines; D051379:Mice; D009154:Mutation; D038541:Neisseria m... | PloS one | 2,015 | D001425:Bacterial Outer Membrane Proteins; C093120:FrpB protein, bacteria; D022401:Meningococcal Vaccines; D018272:Porins; C057699:porin protein, Neisseria |
Real-world data on EGFR/ALK gene status and first-line targeted therapy rate in newly diagnosed advanced non-small cell lung cancer patients in Northern China: A prospective observational study. | BACKGROUND
Tyrosine kinase inhibitors (TKIs) can significantly prolong overall survival for patients with advanced non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR)-mutation or anaplastic lymphoma kinase (ALK)-rearrangement. However, the real-world evaluation status of ALK/EGFR in Chi... | 10.1111/1759-7714.13090 | 31,144,459 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000077548:Anaplastic Lymphoma Kinase; D002289:Carcinoma, Non-Small-Cell Lung; D066246:ErbB Receptors; D005260:Female; D015321:Gene Rearrangement; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D058990:Molecular Targeted Therapy; D00915... | Thoracic cancer | 2,019 | D047428:Protein Kinase Inhibitors; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; C512478:EGFR protein, human; D066246:ErbB Receptors |
Clinical and bacteriological evaluation of netilmicin in gram-negative infections. | A preliminary study was conducted with netilmicin, a new aminoglycoside antibiotic. Its effectiveness was evaluated in vitro against 546 strains of Enterobacteriaceae and Pseudomonas aeruginosa isolated from clinical material. Its effectiveness against gentamicin-susceptible strains was roughly similar to that of genta... | 10.1128/AAC.12.4.503 | 335,960 | D001419:Bacteria; D001424:Bacterial Infections; D002986:Clinical Trials as Topic; D004352:Drug Resistance, Microbial; D005839:Gentamicins; D006801:Humans; D012853:Sisomicin | Antimicrobial agents and chemotherapy | 1,977 | D005839:Gentamicins; D012853:Sisomicin |
Treatment of Wide-Necked Cerebral Aneurysms Using the WEB Device Including Flow Alteration Assessment With Color-Coded Imaging: A Single Center Experience. | Objective
The Woven EndoBridge (WEB) device (MicroVention, Tustin, CA) has extended the treatment of cerebral aneurysms. Despite the fact that the WEB device has shown promising clinical results, little is known about the caused intra-aneurysmal flow alterations. Here we present our clinical experience with the WEB, in... | 10.1016/j.wnsx.2022.100143 | 36,341,134 | World neurosurgery: X | 2,023 | ||
Thrombectomy for late occlusion of high flow extracranial-intracranial saphenous vein bypass graft after 27 years of patency. | High flow extracranial-intracranial (EC-IC) bypass with a saphenous vein graft (SVG) has been used for more than 40 years in patients with giant aneurysms of the posterior circulation refractory to medical management, and has demonstrated high long term patency rates. We report the case of a patient treated with extern... | 10.1136/bcr-2017-013670 | 29,519,858 | D002533:Cerebral Angiography; D002548:Cerebral Revascularization; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm; D008875:Middle Aged; D009460:Neurologic Examination; D010292:Paresthesia; D011183:Postoperative Complications; D012501:Saphenous Vein; D016896:Tr... | BMJ case reports | 2,018 | |
Developing insights into the mechanisms of evolution of bacterial pathogens from whole-genome sequences. | Evolution of bacterial pathogen populations has been detected in a variety of ways including phenotypic tests, such as metabolic activity, reaction to antisera and drug resistance and genotypic tests that measure variation in chromosome structure, repetitive loci and individual gene sequences. While informative, these ... | 10.2217/fmb.12.108 | 23,075,447 | D001419:Bacteria; D001426:Bacterial Proteins; D001483:Base Sequence; D019143:Evolution, Molecular; D016680:Genome, Bacterial; D020641:Polymorphism, Single Nucleotide; D017422:Sequence Analysis, DNA | Future microbiology | 2,012 | D001426:Bacterial Proteins |
The safety of JAK-1 inhibitors. | As efficacy and safety data emerge, differences between JAK inhibitor subclasses are appearing. JAK1 selective drugs, upadacitinib and filgotinib, have broadly come with the same overarching safety recommendations as other immunosuppressive drugs for RA: caution is needed regarding infection risk; monitoring for labora... | 10.1093/rheumatology/keaa895 | 33,950,230 | D001172:Arthritis, Rheumatoid; D056486:Chemical and Drug Induced Liver Injury; D000076385:Diverticular Diseases; D006561:Herpes Simplex; D006562:Herpes Zoster; D006575:Heterocyclic Compounds, 3-Ring; D006801:Humans; D016867:Immunocompromised Host; D007239:Infections; D007416:Intestinal Perforation; D053613:Janus Kinase... | Rheumatology (Oxford, England) | 2,021 | C584571:GLPG0634; D006575:Heterocyclic Compounds, 3-Ring; D000075242:Janus Kinase Inhibitors; D011725:Pyridines; D014230:Triazoles; C000613732:upadacitinib; D053613:Janus Kinase 1 |
A novel strategy for Cr(VI) removal from aqueous solution via CYPH@IL101/chitosan capsule. | A novel adsorbent, chitosan capsule with filler of CYPH@IL101 (CYPH@IL101/chitosan capsule), was prepared using a summary process for the adsorption of Cr(VI) from aqueous solution. The effects of CYPH@IL101 content, pH, contact time, rotational speed and Cr(VI) concentration on the adsorption were studied. The results... | 10.1016/j.ijbiomac.2019.05.125 | 31,154,037 | D000327:Adsorption; D002214:Capsules; D048271:Chitosan; D002857:Chromium; D006863:Hydrogen-Ion Concentration; D052578:Ionic Liquids; D007700:Kinetics; D012996:Solutions; D014867:Water; D014874:Water Pollutants, Chemical; D018508:Water Purification | International journal of biological macromolecules | 2,019 | D002214:Capsules; D052578:Ionic Liquids; D012996:Solutions; D014874:Water Pollutants, Chemical; D014867:Water; D002857:Chromium; C074702:chromium hexavalent ion; D048271:Chitosan |
Genome-wide association studies of leaf angle in maize. | Compact plant-type with small leaf angle has increased canopy light interception, which is conducive to the photosynthesis of the population and higher population yield at high density planting in maize. In this study, a panel of 285 diverse maize inbred lines genotyped with 56,000 SNPs was used to investigate the gene... | 10.1007/s11032-021-01241-0 | 37,309,541 | Molecular breeding : new strategies in plant improvement | 2,021 | ||
Motor cortex stimulation: role of computer modeling. | Motor cortex stimulation (MCS) is a promising clinical technique used to treat chronic, otherwise intractable pain. However, the mechanisms by which the neural elements that are stimulated during MCS induce pain relief are not understood. Neither is it known which of the main neural elements, i.e. cell bodies, dendrite... | 10.1007/978-3-211-33081-4_57 | 17,691,340 | D000818:Animals; D003198:Computer Simulation; D004558:Electric Stimulation; D006801:Humans; D008959:Models, Neurological; D009044:Motor Cortex | Acta neurochirurgica. Supplement | 2,007 | |
Effect of Tetrabutylammonium Bromide-Based Deep Eutectic Solvents on the Aqueous Solubility of Indomethacin at Various Temperatures: Measurement, Modeling, and Prediction with Three-Dimensional Hansen Solubility Parameters. | Deep eutectic solvents (DESs) have recently been getting a great deal of attention in many fields of science and technology. The objective of this study was to peruse the solubility of indomethacin (IMC) as sparingly soluble drug in some tetrabutylammonium bromide (TBAB)-based DESs (TBAB/ethylene glycol and TBAB/glycer... | 10.1208/s12249-019-1373-4 | 31,140,011 | D000894:Anti-Inflammatory Agents, Non-Steroidal; D005544:Forecasting; D007213:Indomethacin; D008956:Models, Chemical; D000644:Quaternary Ammonium Compounds; D012995:Solubility; D012997:Solvents; D013696:Temperature; D013816:Thermodynamics; D014867:Water | AAPS PharmSciTech | 2,019 | D000894:Anti-Inflammatory Agents, Non-Steroidal; D000644:Quaternary Ammonium Compounds; D012997:Solvents; D014867:Water; C009405:tetrabutylammonium; D007213:Indomethacin |
Survival after surgery with cardiopulmonary bypass in low weight patients. | To evaluate risk factors for hospital death in patients weighing < 2.5 kg undergoing open-heart surgery, records of 34 consecutive low-weight patients operated on between December 1997 and November 2004 were reviewed. Mean weight was 2.152 +/- 0.237 kg (range, 1.600 to 2.460 kg). Biventricular repair was achieved in 28... | 10.1177/021849230801600207 | 18,381,868 | D000140:Acidosis, Lactic; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D005260:Female; D005865:Gestational Age; D006330:Heart Defects, Congenital; D017052:Hospital Mortality; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008297:Male; D018579:Patient ... | Asian cardiovascular & thoracic annals | 2,008 | |
Comparison and Optimization of Quantification Methods for Shigella flexneri Serotype 6 O-antigen Containing Galacturonic Acid and Methyl-Pentose. | Shigella is a leading diarrheal cause of morbidity and mortality worldwide, especially in low- and middle-income countries and in children under five years of age. Increasing levels of antimicrobial resistance make vaccine development an even higher global health priority. S. flexneri serotype 6 is one of the targets o... | 10.3390/ijms222212160 | 34,830,042 | D006603:Hexuronic Acids; D019081:O Antigens; D010429:Pentoses; D012763:Shigella flexneri | International journal of molecular sciences | 2,021 | D006603:Hexuronic Acids; D019081:O Antigens; D010429:Pentoses; C007819:galacturonic acid |
Prolonged succinylcholine action during electroconvulsive therapy (ECT) after cytarabine, vincristine, and rituximab chemotherapy. | Succinylcholine is a depolarizing neuromuscular blocker frequently used during electroconvulsive therapy. In most patients, the duration of paralysis is brief, allowing for spontaneous respiration shortly after the therapy. We report a case of delayed return of neuromuscular function after succinylcholine administered ... | 10.1097/YCT.0b013e3181ff2e47 | 21,206,375 | D000368:Aged; D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents; D003561:Cytarabine; D004359:Drug Therapy, Combination; D004565:Electroconvulsive Therapy; D006801:Humans; D008297:Male; D009467:Neuromuscular Depolarizing Agents; D000069283:Rituximab; D013390:Succinylcholine; D013997:Time Fact... | The journal of ECT | 2,011 | D058846:Antibodies, Monoclonal, Murine-Derived; D000970:Antineoplastic Agents; D009467:Neuromuscular Depolarizing Agents; D003561:Cytarabine; D000069283:Rituximab; D014750:Vincristine; D013390:Succinylcholine |
Heterogeneous force network in 3D cellularized collagen networks. | Collagen networks play an important role in coordinating and regulating collective cellular dynamics via a number of signaling pathways. Here, we investigate the transmission of forces generated by contractile cells in 3D collagen-I networks. Specifically, the graph (bond-node) representations of collagen networks with... | 10.1088/1478-3975/13/6/066001 | 27,779,119 | D001696:Biomechanical Phenomena; D024042:Collagen Type I; D021621:Imaging, Three-Dimensional; D008962:Models, Theoretical | Physical biology | 2,016 | D024042:Collagen Type I |
An abattoir-based study on the prevalence of bovine tuberculosis from culled adult dairy cows in Wuhan, China. | Abattoir surveillance is an integral component of a bovine tuberculosis (bTB) eradication programme. The objective of this study was to determine the prevalence of bTB among culled adult dairy cows in Wuhan, China and to further assess two diagnostic procedures as an adjunct to the confirmation of M. bovis in animals w... | 10.1016/j.prevetmed.2021.105477 | 34,482,152 | D000003:Abattoirs; D065136:Animal Culling; D000818:Animals; D001499:Bayes Theorem; D002417:Cattle; D002681:China; D003612:Dairying; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D009163:Mycobacterium bovis; D016133:Polymerase Chain Reaction; D015995:Prevalence; D012680:Sensitivity and Specificity; D016036:... | Preventive veterinary medicine | 2,021 | |
Preoperative diagnosis of THYR 3 versus follicular lesion: malignant postoperative ratio. | AIM
In the evaluation of nodular thyroid lesions, cytology is the main diagnostic instrument, associated with ultrasound examination.
METHODS
We prospectively categorized into a dedicated database, 612 patients submitted to thyroidectomy from January 2009 to December 2011. We selected two groups of patients: the case... | 23,232,481 | D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011446:Prospective Studies; D013959:Thyroid Diseases; D013964:Thyroid Neoplasms; D013965:Thyroidectomy | Minerva chirurgica | 2,012 | ||
How does context influence collaborative decision-making for health services planning, delivery and evaluation? | BACKGROUND
Collaboration among researchers (clinician, non-clinician) and decision makers (managers, policy-makers, clinicians), referred to as integrated knowledge translation (IKT), enhances the relevance and use of research, leading to improved decision-making, policies, practice, and health care outcomes. However I... | 10.1186/s12913-014-0545-x | 25,407,487 | D000328:Adult; D003110:Colonic Neoplasms; D003299:Cooperative Behavior; D003657:Decision Making; D005260:Female; D006282:Health Personnel; D006285:Health Planning; D006302:Health Services Research; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D009864:Ontario; D010190:Pancreatic Neoplasms; D011471:Prostati... | BMC health services research | 2,014 | |
Musicians use speech-specific areas when processing tones: The key to their superior linguistic competence? | It is known that musicians compared to non-musicians have some superior speech and language competence, yet the mechanisms how musical training leads to this advantage are not well specified. This event-related fMRI study confirmed that musicians outperformed non-musicians in processing not only of musical tones but al... | 10.1016/j.bbr.2020.112662 | 32,442,547 | D000328:Adult; D001307:Auditory Perception; D001931:Brain Mapping; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex; D009146:Music; D017397:Prefrontal Cortex; D011578:Psycholinguistics; D013067:Speech Perception; D013702:Temporal Lobe; D055815:Young Adult | Behavioural brain research | 2,020 | |
Endothelium-independent relaxation to cannabinoids in rat-isolated mesenteric artery and role of Ca2+ influx. | (1) Three cannabinoid receptor agonists, anandamide (CB(1) receptor-selective) and the aminoalkyl-indoles, JWH 015(2-methyl-1-propyl-1H-indol-3-yl)-1-napthalenylmethanone; (CB(2) receptor-selective), R-(+)-WIN 55,212-2 (R-(+)-[2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolol[1,2,3-de]-1,4-benzoxazin-6-yl]-1-napthal... | 10.1038/sj.bjp.0705280 | 12,788,818 | D000818:Animals; D002118:Calcium; D015220:Calcium Channels; D002186:Cannabinoids; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular; D066298:In Vitro Techniques; D008297:Male; D008638:Mesenteric Arteries; D051381:Rats; D017208:Rats, Wistar; D014664:Vasodilation | British journal of pharmacology | 2,003 | D015220:Calcium Channels; D002186:Cannabinoids; D002118:Calcium |
Risk factors for the progression of finger interphalangeal joint osteoarthritis: a systematic review. | Progressive hand interphalangeal joint (IPJ) osteoarthritis is associated with pain, reduced function and impaired quality of life. However, the evidence surrounding risk factors for IPJ osteoarthritis progression is unclear. Identifying risk factors for IPJ osteoarthritis progression may inform preventative strategies... | 10.1007/s00296-020-04687-1 | 32,839,851 | D000367:Age Factors; D003920:Diabetes Mellitus; D018450:Disease Progression; D005384:Finger Joint; D006801:Humans; D010003:Osteoarthritis; D012307:Risk Factors; D012737:Sex Factors | Rheumatology international | 2,020 |
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