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How do Ca2+ and 5-aminolevulinic acid-derived oxyradicals promote injury to isolated mitochondria? | The biosynthetic heme precursor 5-aminolevulinic acid (5-ALA) is a generator of oxygen radicals in vitro and possibly in vivo during pathologic situations of 5-ALA overload, for example, acute intermittent porphyria and saturnism. It has been observed that 5-ALA induces, in isolated rat liver mitochondria, permeabiliza... | 10.1016/0891-5849(95)00015-p | 7,557,553 | D000622:Aminolevulinic Acid; D000818:Animals; D002118:Calcium; D002374:Catalase; D004229:Dithiothreitol; D005609:Free Radicals; D017665:Hydroxyl Radical; D007502:Iron Chelating Agents; D008928:Mitochondria; D008930:Mitochondria, Liver; D018384:Oxidative Stress; D010618:Phenanthrolines; D051381:Rats; D013482:Superoxide ... | Free radical biology & medicine | 1,995 | D005609:Free Radicals; D007502:Iron Chelating Agents; D010618:Phenanthrolines; D017665:Hydroxyl Radical; D000622:Aminolevulinic Acid; D002374:Catalase; D013482:Superoxide Dismutase; D002118:Calcium; D004229:Dithiothreitol; C025205:1,10-phenanthroline |
Clinician Perspectives on Barriers and Facilitators to Implementing e-Health Technology in Substance Use Disorder (SUD) Treatment Facilities. | BACKGROUND
Substance use disorders (SUDs) in the United States cause many preventable deaths each year. Finding effective ways to manage SUDs is vital to improving outcomes for individuals seeking treatment. This has increased interest in using e-health technologies in behavioral healthcare settings. This research is p... | 10.1177/11782218211053360 | 34,720,585 | Substance abuse : research and treatment | 2,021 | ||
Healthcare Utilization Survey in the Hybrid Model of the Surveillance for Enteric Fever in India (SEFI) Study: Processes, Monitoring, Results, and Challenges. | BACKGROUND
Lack of reliable data in India drove the "Surveillance of Enteric Fever in India" (SEFI) concept. Hybrid surveillance, combining facility-based surveillance for the crude incidence, and a community-based healthcare utilization survey (HCUS) to calculate the factor needed to arrive at the adjusted incidence, ... | 10.1093/infdis/jiab371 | 35,238,353 | D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007194:India; D010342:Patient Acceptance of Health Care; D012424:Rural Population; D014435:Typhoid Fever | The Journal of infectious diseases | 2,021 | |
Telephone follow-up in primary care: can interactive voice response calls work? | UNLABELLED
Follow-up calls after ambulatory visits are not routinely done, yet they can potentially detect and mitigate unresolved problems. Automated calls via an Interactive Voice Response System (IVRS) are an innovative way to conduct follow-up, but patients' attitudes toward follow-up calls are unknown. This study ... | 23,920,526 | D000407:Alabama; D000553:Ambulatory Care; D003266:Continuity of Patient Care; D019538:Health Care Surveys; D006801:Humans; D010358:Patient Participation; D017060:Patient Satisfaction; D011320:Primary Health Care; D019114:Remote Consultation; D049250:Speech Recognition Software; D013689:Telephone; D014584:User-Computer ... | Studies in health technology and informatics | 2,013 | ||
The relative sensitivity of growth and reproduction in the springtail, Folsomia candida, exposed to xenobiotics in the laboratory: an indicator of soil toxicity. | The Folsomia candida reproduction test [ISO, 1998. Soil quality--Inhibition of reproduction of Collembola (Folsomia candida) by soil pollutants. International Standard Organization Report 11267, 1998, Geneva] is used to evaluate the ecotoxicological risks of contaminants in soils. The aim of this study was to compare t... | 10.1016/j.ecoenv.2005.06.002 | 16,040,122 | D000535:Aluminum; D000818:Animals; D001151:Arsenic; D001181:Arthropods; D002104:Cadmium; D004785:Environmental Pollutants; D010416:Pentachlorophenol; D012098:Reproduction; D012989:Soil Pollutants; D018675:Toxicity Tests; D015262:Xenobiotics | Ecotoxicology and environmental safety | 2,006 | D004785:Environmental Pollutants; D012989:Soil Pollutants; D015262:Xenobiotics; D002104:Cadmium; D000535:Aluminum; D010416:Pentachlorophenol; D001151:Arsenic |
Redox interaction of Mn-bicarbonate complexes with reaction centres of purple bacteria. | It is found that dark reduction of photooxidized primary electron donor P870+ in reaction centres from purple anoxygenic bacteria (two non-sulphur Fe-oxidizing Rhodovulum iodosum and Rhodovulum robiginosum, Rhodobacter sphaeroides R-26 and sulphur alkaliphilic Thiorhodospira sibirica) is accelerated upon the addition o... | 10.1098/rstb.2007.2221 | 17,971,330 | D001639:Bicarbonates; D007700:Kinetics; D008345:Manganese; D010084:Oxidation-Reduction; D045322:Photosynthetic Reaction Center Complex Proteins; D012242:Rhodobacter sphaeroides; D013056:Spectrophotometry, Ultraviolet | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 2,008 | D001639:Bicarbonates; D045322:Photosynthetic Reaction Center Complex Proteins; D008345:Manganese |
Surgical and implant-supported fixed prosthetic treatment of a patient with ectodermal dysplasia: a case report. | Ectodermal dysplasia (ED) is a hereditary disorder that affects ectodermal structures. The main clinical oral manifestations of ED include oligodontia and deficient alveolar ridges. This case report presents the oral rehabilitation of a 15-year-old female patient who never received an accurate diagnosis or appropriate ... | 10.1111/j.1754-4505.2011.00222.x | 22,229,591 | D000293:Adolescent; D000540:Alveolar Ridge Augmentation; D000848:Anodontia; D002680:Chin; D003442:Crowns; D017742:Dental Care for Chronically Ill; D003758:Dental Implantation, Endosseous; D019094:Dental Prosthesis, Implant-Supported; D003830:Denture, Partial, Fixed; D004476:Ectodermal Dysplasia; D005260:Female; D006801... | Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry | 2,012 | |
Glyap1 regulates pneumocandin B0 synthesis by controlling the intracellular redox balance in Glarea lozoyensis. | Pneumocandin B0, the precursor of the antifungal drug caspofungin, is a lipohexapeptide produced by the fungus Glarea lozoyensis. Oxidative stress and the resulting production of reactive oxygen species (ROS) are known to be involved in the regulation of pneumocandin B0 biosynthesis. In this study, the Glyap1 gene of G... | 10.1007/s00253-021-11522-5 | 34,476,516 | D001203:Ascomycota; D054714:Echinocandins; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D017382:Reactive Oxygen Species | Applied microbiology and biotechnology | 2,021 | D054714:Echinocandins; D017382:Reactive Oxygen Species; C079465:pneumocandin B(0) |
NuCLS: A scalable crowdsourcing approach and dataset for nucleus classification and segmentation in breast cancer. | BACKGROUND
Deep learning enables accurate high-resolution mapping of cells and tissue structures that can serve as the foundation of interpretable machine-learning models for computational pathology. However, generating adequate labels for these structures is a critical barrier, given the time and effort required from ... | 10.1093/gigascience/giac037 | 35,579,553 | D001943:Breast Neoplasms; D002467:Cell Nucleus; D063045:Crowdsourcing; D005260:Female; D006801:Humans; D000069550:Machine Learning | GigaScience | 2,022 | |
Bioaerosol and microbial exposures from residential evaporative coolers and their potential health outcomes: A review. | Evaporative cooling is an energy efficient form of air conditioning in dry climates that functions by pulling hot, dry outdoor air across a wet evaporative pad. While evaporative coolers can help save energy, they also have the potential to influence human health. Studies have shown residential evaporative coolers may ... | 10.1111/ina.13082 | 36,168,234 | D000393:Air Pollutants; D016902:Air Pollution, Indoor; D004391:Dust; D004731:Endotoxins; D005936:Glucans; D006798:Housing; D006801:Humans | Indoor air | 2,022 | D000393:Air Pollutants; D004391:Dust; D004731:Endotoxins; D005936:Glucans |
Colon examination in patients with proven colorectal cancer. | It has been recommended that all patients with proven colorectal cancer should have a total colon check. This prospective study examines the practical implementation of this recommendation. It demonstrates the extent to which clinical practice may appear to drift away from a guideline, whilst remaining entirely justifi... | 10.1046/j.1463-1318.1999.00086.x | 23,574,595 | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland | 1,999 | ||
Line orientation adaptation: local or global? | Prolonged exposure to an oriented line shifts the perceived orientation of a subsequently observed line in the opposite direction, a phenomenon known as the tilt aftereffect (TAE). Here we consider whether the TAE for line stimuli is mediated by a mechanism that integrates the local parts of the line into a single glob... | 10.1371/journal.pone.0073307 | 24,023,677 | D000221:Adaptation, Ocular; D015350:Contrast Sensitivity; D005366:Figural Aftereffect; D006801:Humans; D008959:Models, Neurological; D009949:Orientation; D010775:Photic Stimulation | PloS one | 2,013 | |
Stress analysis of the thoracolumbar junction in the process of backward fall: An experimental study and finite element analysis. | The aim of the present study was to evaluate the biomechanical mechanism of injuries of the thoracolumbar junction by the methods of a backward fall simulation experiment and finite element (FE) analysis (FEA). In the backward fall simulation experiment, one volunteer was selected to obtain the contact force data of th... | 10.3892/etm.2021.10551 | 34,504,571 | Experimental and therapeutic medicine | 2,021 | ||
ASTCT, CIBMTR, and EBMT clinical practice recommendations for transplant and cellular therapies in mantle cell lymphoma. | Autologous (auto-) or allogeneic (allo-) hematopoietic cell transplantation (HCT) are accepted treatment modalities for mantle cell lymphoma (MCL). Recently, chimeric antigen receptor (CAR) T-cell therapy received approval for MCL; however, its exact place and sequence in relation to HCT is unclear. The ASTCT, CIBMTR, ... | 10.1038/s41409-021-01288-9 | 34,413,469 | D000328:Adult; D064987:Cell- and Tissue-Based Therapy; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D020522:Lymphoma, Mantle-Cell; D019172:Transplantation Conditioning; D014182:Transplantation, Autologous | Bone marrow transplantation | 2,021 | |
Structured follow-up pathway to support people after transient ischaemic attack and minor stroke (SUPPORT TIA): protocol for a feasibility study and process evaluation. | INTRODUCTION
People who experience transient ischaemic attack (TIA) and minor stroke have limited follow-up despite rapid specialist review in hospital. This means they often have unmet needs and feel abandoned following discharge. Care needs after TIA/minor stroke include information provision (diagnosis and stroke ri... | 10.1136/bmjopen-2021-060280 | 35,710,247 | D005240:Feasibility Studies; D005500:Follow-Up Studies; D006801:Humans; D002546:Ischemic Attack, Transient; D015337:Multicenter Studies as Topic; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D020521:Stroke | BMJ open | 2,022 | |
[Susceptibility to azoles and amphotericin B of isolates of Candida spp. Experience of a university health network, between 2004 and 2010]. | OBJECTIVE
To describe antifungal susceptibility testing surveillance (December 2004-September 2010) in Candida spp., for amphotericin B, fluconazole and voriconazole, at the Laboratorio de Microbiología, Pontificia Universidad Católica de Chile.
METHOD
The study was performed utilizing E test and included yeasts from... | 22,689,028 | D000666:Amphotericin B; D000935:Antifungal Agents; D002175:Candida; D002677:Chile; D015331:Cohort Studies; D025141:Drug Resistance, Fungal; D015725:Fluconazole; D006801:Humans; D008826:Microbial Sensitivity Tests; D011743:Pyrimidines; D012189:Retrospective Studies; D014230:Triazoles; D065819:Voriconazole | Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia | 2,012 | D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D000666:Amphotericin B; D015725:Fluconazole; D065819:Voriconazole | |
Long-term Gadolinium Retention in the Healthy Rat Brain: Comparison between Gadopiclenol, Gadobutrol, and Gadodiamide. | Background Safety concerns caused by gadolinium retention call for the development of high-relaxivity gadolinium-based contrast agents (GBCAs) allowing minimal dosing. Purpose To investigate brain gadolinium retention in healthy rats after exposure to gadopiclenol (Elucirem, Guerbet; macrocyclic GBCA) compared with gad... | 10.1148/radiol.212600 | 35,727,155 | D000818:Animals; D053961:Azabicyclo Compounds; D001921:Brain; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D007501:Iron; D008297:Male; D009942:Organometallic Compounds; D051381:Rats; D017207:Rats, Sprague-Dawley | Radiology | 2,022 | D053961:Azabicyclo Compounds; D003287:Contrast Media; D009942:Organometallic Compounds; C090600:gadobutrol; C064925:gadodiamide; D005682:Gadolinium; D007501:Iron; D019786:Gadolinium DTPA; C000656634:gadopiclenol |
A comparison of the effect of attention training and relaxation on responses to pain. | This study aimed to investigate the efficacy of an attention training technique (ATT) on pain ratings, threshold and tolerance during the cold pressor task. One hundred and three undergraduate students were randomly assigned to receive either threat-alleviating or threat-inducing information about the task. Participant... | 10.1016/j.pain.2010.05.027 | 20,619,540 | D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D001288:Attention; D003072:Cognition Disorders; D005239:Fear; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010146:Pain; D010147:Pain Measurement; D017288:Pain Thre... | Pain | 2,010 | |
Enhanced dewatering of waste-activated sludge by composite hydrolysis enzymes. | The feasibility of composite hydrolysis enzymes in enhanced dewatering of waste-activated sludge (WAS) was verified in this study. A Pearson correlation analysis was conducted to explore the roles of different extracellular polymeric substance (EPS) fractions on WAS dewaterability. The results indicated that tightly bo... | 10.1007/s00449-016-1544-6 | 26,815,556 | D006867:Hydrolases; D008956:Models, Chemical; D012722:Sewage | Bioprocess and biosystems engineering | 2,016 | D012722:Sewage; D006867:Hydrolases |
Detection of extrinsic bronchial compression during foreign body removal by pulse oximetry. | A case of stridor is described which was due to the presence of a foreign body in the larynx of an infant. Following partial removal, compression of the right main bronchus was detected because of continuing low arterial oxygen saturation. The use of pulse oximetry allowed this complication to be identified, and the ad... | 10.1017/s002221510011179x | 2,313,179 | D000402:Airway Obstruction; D001980:Bronchi; D003251:Constriction, Pathologic; D004947:Esophagus; D005547:Foreign Bodies; D006801:Humans; D007223:Infant; D007830:Larynx; D008297:Male; D010092:Oximetry; D012135:Respiratory Sounds | The Journal of laryngology and otology | 1,990 | |
Morphological changes of stria vascularis in congenital hearing impairment due to membranous labyrinth underdevelopment. | Congenital malformations of the inner ear may involve either the bone and membranous labyrinth or the membranous labyrinth alone. The same labyrinth structures can be affected with an acquired disease, toxaemia or viral labyrinthitis, for instance, with the same or very similar histologic findings. So far, there have b... | 10.3109/00016489709113430 | 9,288,205 | D000293:Adolescent; D000328:Adult; D000368:Aged; D001284:Atrophy; D002648:Child; D003051:Cochlea; D003638:Deafness; D007758:Ear, Inner; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D013316:Stria Vascularis | Acta oto-laryngologica | 1,997 | |
Development of an endoluminal intestinal lengthening capsule. | PURPOSE
Prior studies demonstrated the ability of a spring to lengthen intestinal segments. We made two innovations to this device. First, we employed a degradable capsule to control the deployment of the spring. Second, we decreased the spring force to allow slower expansion of the intestinal segment.
METHODS
Nitino... | 10.1016/j.jpedsurg.2011.10.031 | 22,244,406 | D000818:Animals; D002214:Capsules; D004867:Equipment Design; D005260:Female; D051381:Rats; D017207:Rats, Sprague-Dawley; D012778:Short Bowel Syndrome; D015625:Tissue Expansion Devices | Journal of pediatric surgery | 2,012 | D002214:Capsules |
Applying management strategies in molecular epidemiology field studies. | In conducting field studies of human exposure, we have encountered significant methodological challenges. The management strategy our group developed to conduct two recent studies of environmental health utilizes a collaborative study design process and innovative protocol management tools, and emphasizes community out... | 10.1002/(SICI)1099-1751(199701)12:1<63::AID-HPM450>3.0.CO;2-A | 10,167,615 | D002031:Bulgaria; D002857:Chromium; D018672:Community Health Planning; D004781:Environmental Exposure; D004812:Epidemiologic Methods; D005557:Formaldehyde; D006801:Humans; D007400:Interprofessional Relations; D017720:Molecular Epidemiology; D009515:New Jersey; D016273:Occupational Exposure; D012107:Research Design | The International journal of health planning and management | 1,997 | D002857:Chromium; D005557:Formaldehyde |
The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum. | BACKGROUND
The uptake of nutrients, expulsion of metabolic wastes and maintenance of ion homeostasis by the intraerythrocytic malaria parasite is mediated by membrane transport proteins. Proteins of this type are also implicated in the phenomenon of antimalarial drug resistance. However, the initial annotation of the g... | 10.1186/gb-2005-6-3-r26 | 15,774,027 | D000595:Amino Acid Sequence; D026905:Amino Acid Transport Systems; D000818:Animals; D019295:Computational Biology; D033705:Equilibrative Nucleoside Transport Proteins; D004912:Erythrocytes; D023281:Genomics; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007473:Ion Channels; D016778:Malaria, Falcipa... | Genome biology | 2,005 | D026905:Amino Acid Transport Systems; D033705:Equilibrative Nucleoside Transport Proteins; D007473:Ion Channels; D026901:Membrane Transport Proteins; D015800:Protozoan Proteins; D016053:RNA, Protozoan |
Bipolar Disorder and Obesity: Contributing Factors, Impact on Clinical Course, and the Role of Bariatric Surgery. | PURPOSE OF REVIEW
Bipolar disorder (BD) is a severe, common, and chronic affective disorder. This review highlights the BD and obesity connection and the role of treatments for obesity in this population.
RECENT FINDINGS
Patients with BD are at a significantly increased risk for obesity, as compared to those without ... | 10.1007/s13679-018-0322-y | 30,368,736 | D014150:Antipsychotic Agents; D050110:Bariatric Surgery; D001714:Bipolar Disorder; D015897:Comorbidity; D001068:Feeding and Eating Disorders; D006801:Humans; D009765:Obesity | Current obesity reports | 2,018 | D014150:Antipsychotic Agents |
Estimating the Health-Related Quality of Life of Twitter Users Using Semantic Processing. | Social media presents a rich opportunity to gather health information with limited intervention through the analysis of completely unstructured and unlabeled microposts. We sought to estimate the health-related quality of life (HRQOL) of Twitter users using automated semantic processing methods. We collected tweets fro... | 10.3233/SHTI190388 | 31,438,088 | D003625:Data Collection; D006304:Health Status; D006801:Humans; D011788:Quality of Life; D012660:Semantics; D061108:Social Media | Studies in health technology and informatics | 2,019 | |
Myospherulosis of the lower lip. Report of a case. | A 19-year-old man with myospherulosis of the lower lip is described. The lesion was probably caused by petrolatum-based antibiotic ointment. | 10.1016/s0901-5027(05)80643-5 | 8,409,566 | D000328:Adult; D004912:Erythrocytes; D006801:Humans; D007049:Iatrogenic Disease; D008047:Lip Diseases; D008297:Male; D009078:Mucocele; D010577:Petrolatum; D013281:Stomatitis, Aphthous | International journal of oral and maxillofacial surgery | 1,993 | D010577:Petrolatum |
Influence of CGS 9343B, an inhibitor of calmodulin activity, on histamine release from isolated rat mast cells. | Investigations of calmodulin involvement in cell responses has been complicated by the lack of selective calmodulin antagonists. A novel inhibitor, CGS 9343B, reportedly without influence on protein kinase C, is used in the present study of mast cell responses. The histamine release induced by antigen and compound 48/8... | 1,382,372 | D000818:Animals; D001562:Benzimidazoles; D000001:Calcimycin; D002147:Calmodulin; D006636:Histamine Release; D066298:In Vitro Techniques; D008297:Male; D008407:Mast Cells; D051381:Rats; D011919:Rats, Inbred Strains; D013755:Tetradecanoylphorbol Acetate; D003189:p-Methoxy-N-methylphenethylamine | Agents and actions | 1,992 | D001562:Benzimidazoles; D002147:Calmodulin; C052087:CGS 9343B; D000001:Calcimycin; D003189:p-Methoxy-N-methylphenethylamine; D013755:Tetradecanoylphorbol Acetate | |
PML-RARalpha inhibitors (ATRA, tamibaroten, arsenic troxide) for acute promyelocytic leukemia. | Acute promyelocytic leukemia (APL) is characterized by generation of the PML-RARalpha fusion gene. PML-RARalpha can homodimerize with another PML-RARalpha, and the hybrid binds the histone-deacetylase recruiting co-repressor complex with higher affinity than the wild-type RARalpha. However, the co-repressor complex is ... | 10.1007/s10147-007-0694-6 | 17,929,112 | D000818:Animals; D000970:Antineoplastic Agents; D000077237:Arsenic Trioxide; D001152:Arsenicals; D001565:Benzoates; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute; D015514:Oncogene Proteins, Fusion; D010087:Oxides; D013764:Tetrahydronaphthalenes; D014212:Tretinoin | International journal of clinical oncology | 2,007 | D000970:Antineoplastic Agents; D001152:Arsenicals; D001565:Benzoates; D015514:Oncogene Proteins, Fusion; D010087:Oxides; D013764:Tetrahydronaphthalenes; C093476:promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein; C061133:tamibarotene; D014212:Tretinoin; D000077237:Arsenic Trioxide |
Chemiluminescence detection flow cells for flow injection analysis and high-performance liquid chromatography. | We have examined a range of new and previously described flow cells for chemiluminescence detection. The reactions of acidic potassium permanganate with morphine and amoxicillin were used as model systems representing the many fast chemiluminescence reactions between oxidising agents and organic analytes, and the preli... | 10.1007/s00216-012-5902-1 | 22,453,605 | Analytical and bioanalytical chemistry | 2,012 | ||
Pretransplant BK Virus-Specific T-Cell-Mediated Immunity and Serotype Specific Antibodies May Have Utility in Identifying Patients at Risk of BK Virus-Associated Haemorrhagic Cystitis after Allogeneic HSCT. | BK polyomavirus (BKPyV) persists lifelong in renal and urothelial cells with asymptomatic urinary shedding in healthy individuals. In some immunocompromised persons after transplantation of hematopoietic stem cells (HSCT), the BKPyV high-rate replication is associated with haemorrhagic cystitis (HC). We tested whether ... | 10.3390/vaccines9111226 | 34,835,157 | Vaccines | 2,021 | ||
Myocardial infarction throughout 1 year of the COVID-19 pandemic: French nationwide study of hospitalization rates, prognosis and 90-day mortality rates. | BACKGROUND
Studies reported a decrease in hospital admissions for myocardial infarction (MI) in early 2020 as a result of the coronavirus disease 2019 (COVID-19) crisis, mainly restricted to the beginning of the pandemic.
AIMS
To describe national trends in hospital admissions for MI in 2020, and to compare patient c... | 10.1016/j.acvd.2021.10.008 | 34,840,126 | D000359:Aftercare; D000368:Aged; D000086382:COVID-19; D003140:Communicable Disease Control; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D009203:Myocardial Infarction; D058873:Pandemics; D010351:Patient Discharge; D011379:Prognosis; D000086402:SARS-CoV-2 | Archives of cardiovascular diseases | 2,021 | |
The effect of diet and exercise on lipid droplet dynamics in human muscle tissue. | The majority of fat in the human body is stored as triacylglycerols in white adipose tissue. In the obese state, adipose tissue mass expands and excess lipids are stored in non-adipose tissues, such as skeletal muscle. Lipids are stored in skeletal muscle in the form of small lipid droplets. Although originally viewed ... | 10.1242/jeb.167015 | 29,514,886 | D004032:Diet; D015444:Exercise; D006801:Humans; D007333:Insulin Resistance; D066292:Lipid Droplets; D032342:Muscle Cells; D009132:Muscles | The Journal of experimental biology | 2,018 | |
Fulcrum: condensing redundant reads from high-throughput sequencing studies. | MOTIVATION
Ultra-high-throughput sequencing produces duplicate and near-duplicate reads, which can consume computational resources in downstream applications. A tool that collapses such reads should reduce storage and assembly complications and costs.
RESULTS
We developed Fulcrum to collapse identical and near-identi... | 10.1093/bioinformatics/bts123 | 22,419,786 | D000465:Algorithms; D020869:Gene Expression Profiling; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D011549:Pseudomonas; D017422:Sequence Analysis, DNA; D012984:Software | Bioinformatics (Oxford, England) | 2,012 | |
A versatile switchable dual-modal colorimetric and photoelectrochemical biosensing strategy via light-controlled sway of a signal-output transverter. | A design criterion to construct a versatile dual-modal colorimetric and PEC biosensing platform for switching the corresponding mode freely is proposed via integration of a natural enzyme, light-activated nanozyme and light-controlled swayable signal-output transverter. A switchable dual-modal platform toward DNA analy... | 10.1039/d1cc00324k | 33,645,600 | D015374:Biosensing Techniques; D003124:Colorimetry; D004247:DNA; D055664:Electrochemical Techniques; D004867:Equipment Design; D008027:Light | Chemical communications (Cambridge, England) | 2,021 | D004247:DNA |
Effects of different deodorization methods on the oxidation of sterol components in rice bran oil. | Rice bran oil contains a significant quantity of phytosterols that have various active functions and are natural active substances beneficial to humans. It is well known that deodorization during refining affects the quality of rice bran oil. However, changes in phytosterols fraction caused by stripping with nitrogen c... | 10.1016/j.foodchem.2022.134568 | 36,252,381 | D006801:Humans; D000073879:Rice Bran Oil; D013261:Sterols; D013227:Steam; D010840:Phytosterols; D009584:Nitrogen | Food chemistry | 2,023 | D000073879:Rice Bran Oil; D013261:Sterols; D013227:Steam; D010840:Phytosterols; D009584:Nitrogen |
Distribution and possible origin of galanin-like immunoreactive nerve fibers in the mammalian dental pulp. | Human, dog, cat and rat dental pulps were investigated for the presence and distribution of galanin-like immunoreactive (-IR) nerve fibers, and the possible origin of pulpal galanin-IR nerve fibers in the rat was examined. Galanin-IR nerve fibers were present in the dental pulps of all species examined. Two types of ga... | 10.1016/0167-0115(96)00016-x | 8,795,077 | D000818:Animals; D002415:Cats; D003714:Denervation; D003782:Dental Pulp; D004285:Dogs; D019004:Galanin; D006801:Humans; D007150:Immunohistochemistry; D009412:Nerve Fibers; D051381:Rats | Regulatory peptides | 1,996 | D019004:Galanin |
The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein. | The heterodimeric transcription elongation factor Spt4/Spt5 (Spt4/5) tightly associates with RNAPII to regulate both transcriptional elongation and co-transcriptional pre-mRNA processing; however, the mechanisms by which Spt4/5 acts are poorly understood. Recent studies of the human and Drosophila Spt4/5 complexes indi... | 10.1002/pro.2976 | 27,376,968 | D000818:Animals; D002868:Chromosomal Proteins, Non-Histone; D004331:Drosophila melanogaster; D006801:Humans; D009687:Nuclear Proteins; D000072417:Protein Domains; D012319:RNA Polymerase II; D016601:RNA-Binding Proteins; D012441:Saccharomyces cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D035602:Transcriptional... | Protein science : a publication of the Protein Society | 2,016 | D002868:Chromosomal Proteins, Non-Histone; D009687:Nuclear Proteins; D016601:RNA-Binding Proteins; C080991:SPT4 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D035602:Transcriptional Elongation Factors; C069940:SPT5 transcriptional elongation factor; D012319:RNA Polymerase II |
Bioactivity and properties of an adhesive system functionalized with an experimental niobium-based glass. | OBJECTIVE
This study evaluated the incorporation of niobophosphate bioactive glass (NbG) fillers into a commercial adhesive resin.
MATERIALS AND METHODS
The silanized (NbGs) or non-silanized (NbG) NbG was added to the commercial adhesive system One Step (OS) at 30% by weight; unfilled adhesive served as control. The ... | 10.1016/j.jmbbm.2017.11.016 | 29,169,095 | D000269:Adhesives; D005898:Glass; D006244:Hardness; D008422:Materials Testing; D055595:Mechanical Phenomena; D009556:Niobium; D013718:Tensile Strength | Journal of the mechanical behavior of biomedical materials | 2,018 | D000269:Adhesives; D009556:Niobium |
Complex challenges should be approached by a multitude of theories and models. | The ongoing pandemic may be regarded as a wicked problem. Therefore, it should be analyzed by a multitude of theories and models. Approaching the complex set of challenges posed to individuals and society by singular methods, can lead to suboptimal decisions. Good decisions must take into account the large set of uncer... | 10.1111/risa.13923 | 36,351,748 | D006801:Humans; D013673:Technology Assessment, Biomedical; D035501:Uncertainty | Risk analysis : an official publication of the Society for Risk Analysis | 2,023 | |
Renal Abnormalities Caused by Canine Distemper Virus Infection in Terminal Patients. | The aim of this study was to analyze the glomerular and tubular alterations in dogs with terminal distemper through light microscopy, immunofluorescence, and electron microscopy. Thirteen animals with a molecular diagnosis of distemper and neurological signs were selected. As a control group, 10 clinically healthy anim... | 10.3389/fvets.2022.822525 | 35,350,433 | Frontiers in veterinary science | 2,022 | ||
Burn size and environmental conditions modify thermoregulatory responses to exercise in burn survivors. | This project tested the hypothesis that burn survivors can perform mild/moderate-intensity exercise in temperate and hot environments without excessive elevations in core body temperature. Burn survivors with low (23±5%TBSA; N=11), moderate (40±5%TBSA; N=9), and high (60±8%TBSA; N=9) burn injuries performed 60 minutes ... | 10.1093/jbcr/irad128 | 37,615,621 | Journal of burn care & research : official publication of the American Burn Association | 2,023 | ||
Acidosis and Formaldehyde Secretion as a Possible Pathway of Cancer Pain and Options for Improved Cancer Pain Control. | The prevalence of cancer pain in patients with cancer is high. The majority of efforts are spent on research in cancer treatment, but only a small fraction focuses on cancer pain. Pain in cancer patients, viewed predominantly as a secondary issue, is considered to be due to the destruction of tissues, compression of th... | 10.3109/15360288.2015.1063561 | 26,368,037 | D000138:Acidosis; D000444:Aldehyde Dehydrogenase; D003999:Dichloroacetic Acid; D005557:Formaldehyde; D005978:Glutathione; D006801:Humans; D006863:Hydrogen-Ion Concentration; D019344:Lactic Acid; D009369:Neoplasms; D010146:Pain; D059408:Pain Management; D011788:Quality of Life; D000077185:Resveratrol; D017693:Sodium Bic... | Journal of pain & palliative care pharmacotherapy | 2,015 | D013267:Stilbenes; D005557:Formaldehyde; D019344:Lactic Acid; D017693:Sodium Bicarbonate; D003999:Dichloroacetic Acid; D000444:Aldehyde Dehydrogenase; D005978:Glutathione; D000077185:Resveratrol |
[Demonstration of the angiogenic cytokine vascular endothelial growth factor (VEGF) by non radioactive in situ hybridization]. | In tumor angiogenesis Vascular Endothelial Growth Factor (VEGF) has an important role due to its target cell specificity. It is expressed by the tumor and effects on a paracrine pathway. To increase the understanding of its regulation, it is necessary to identify those cells releasing VEGF. This can be done by in situ ... | 9,480,624 | D003106:Colon; D015179:Colorectal Neoplasms; D018076:DNA, Complementary; D016228:Endothelial Growth Factors; D006801:Humans; D017403:In Situ Hybridization; D008222:Lymphokines; D009389:Neovascularization, Pathologic; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors | Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft | 1,997 | D018076:DNA, Complementary; D016228:Endothelial Growth Factors; D008222:Lymphokines; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors | |
The Resurrection of Phenotypic Drug Discovery. | Prior to genetic mapping, the majority of drug discovery efforts involved phenotypic screening, wherein compounds were screened in either in vitro or in vivo models thought to mimic the disease state of interest. While never completely abandoning phenotypic approaches, the labor intensive nature of such tests encourage... | 10.1021/acsmedchemlett.0c00006 | 33,062,159 | ACS medicinal chemistry letters | 2,020 | ||
Infant attachment and temperament as predictors of subsequent externalizing problems and cardiac physiology. | BACKGROUND
The primary objective of this study was to examine the extent to which both individual child temperament and parent-child relationship quality independently and/or interactively predicted physiological, psychosocial, and behavioral 'outcomes'. Employing a longitudinal prospective design over three years, sta... | 10.1111/1469-7610.00167 | 12,959,491 | D000704:Analysis of Variance; D001145:Arrhythmias, Cardiac; D002320:Cardiovascular Physiological Phenomena; D002675:Child, Preschool; D003674:Defense Mechanisms; D005260:Female; D005544:Forecasting; D006339:Heart Rate; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D009769:Object Attachment... | Journal of child psychology and psychiatry, and allied disciplines | 2,003 | |
Long noncoding RNA FAM157C contributes to clonal proliferation in paroxysmal nocturnal hemoglobinuria. | Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal disease of hematopoietic stem cells (HSCs). Long noncoding RNAs (lncRNAs) perform a wide range of biological functions, including the regulation of gene expression, cell differentiation, and proliferation, but their role in PNH remains unclear.CD59- and CD59+ g... | 10.1007/s00277-022-05055-8 | 36,607,351 | D006801:Humans; D006457:Hemoglobinuria, Paroxysmal; D062085:RNA, Long Noncoding; D006412:Hematopoietic Stem Cells; D002999:Clone Cells; D018957:CD59 Antigens; D049109:Cell Proliferation; D012333:RNA, Messenger | Annals of hematology | 2,023 | D062085:RNA, Long Noncoding; D018957:CD59 Antigens; D012333:RNA, Messenger |
Expression dynamics and genome distribution of osmoprotectants in soybean: identifying important components to face abiotic stress. | BACKGROUND
Despite the importance of osmoprotectants, no previous in silico evaluation of high throughput data is available for higher plants. The present approach aimed at the identification and annotation of osmoprotectant-related sequences applied to short transcripts from a soybean HT-SuperSAGE (High Throughput Sup... | 10.1186/1471-2105-14-S1-S7 | 23,369,061 | D016000:Cluster Analysis; D020224:Expressed Sequence Tags; D020869:Gene Expression Profiling; D017343:Genes, Plant; D018745:Genome, Plant; D059014:High-Throughput Nucleotide Sequencing; D009997:Osmotic Pressure; D012639:Seeds; D013025:Glycine max; D013312:Stress, Physiological; D026801:Synteny | BMC bioinformatics | 2,013 | |
Relationship between the extent of coronary artery disease and in-stent restenosis in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. | OBJECTIVE
The pathophysiological mechanism of in-stent restenosis (ISR) is different from atherosclerosis of native coronary arteries. The aim of this study was to evaluate the relationship between ISR and the extent of coronary artery disease (CAD), and to identify other risk factors associated with ISR in ST-segment ... | 10.5543/tkda.2017.72921 | 29,226,890 | D000368:Aged; D003324:Coronary Artery Disease; D023903:Coronary Restenosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D062645:Percutaneous Coronary Intervention; D012189:Retrospective Studies | Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir | 2,017 | |
Prostatic adenocarcinoma in colorectal biopsy: clinical and pathologic features. | Locally advanced prostate carcinoma (PCa) can involve adjacent colorectal tissue. In such cases, accurate assignment of primary source may prove difficult. Given the difference in treatment and prognosis between PCa and colorectal carcinoma (CRCa), an accurate diagnosis is crucial. Surgical pathology files were searche... | 10.1016/j.humpath.2007.08.011 | 18,234,278 | D000230:Adenocarcinoma; D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor; D001706:Biopsy; D002277:Carcinoma; D015179:Colorectal Neoplasms; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms | Human pathology | 2,008 | D014408:Biomarkers, Tumor |
The Schwartz-Bartter syndrome in patients admitted to a general surgical unit following trauma. | Two patients are described with the Schwartz-Bartter syndrome (Bartter and Schwartz, 1967; Barter, 1973). The first followed concussion, the second followed a chest injury with accompanying minor head injury. The clinical features and treatment of this condition are briefly discussed. Awareness of this potentially seri... | 10.1016/0020-1383(85)90060-9 | 4,008,038 | D000328:Adult; D006259:Craniocerebral Trauma; D006801:Humans; D007177:Inappropriate ADH Syndrome; D008297:Male; D011018:Pneumonia, Pneumococcal; D013898:Thoracic Injuries | Injury | 1,985 | |
Perceived proprietary right to resources and its role in reciprocal prejudices between Black and Asian Americans. | I offer a new measure of perceived proprietary right (PPR) to resources as an operationalization of one critical aspect of Harold Blumer's group threat theory. Black (n = 82), Asian (n = 72), and White (n = 176) participants completed PPR items in the context of a residential resource allocation task designed to evoke ... | 10.1080/00224545.2021.1896467 | 33,706,679 | The Journal of social psychology | 2,021 | ||
The prognostic value of m6A-related LncRNAs in patients with HNSCC: bioinformatics analysis of TCGA database. | N6-methyladenosine (m6A) modifications play an essential role in tumorigenesis. These modifications modulate RNAs, including mRNAs and lncRNAs. However, the prognostic role of m6A-related lncRNAs in head and neck squamous cell carcinoma (HNSCC) is poorly understood. Based on LASSO Cox regression, enrichment analysis, u... | 10.1038/s41598-021-04591-z | 35,022,464 | D000241:Adenosine; D000368:Aged; D015331:Cohort Studies; D019295:Computational Biology; D005260:Female; D006258:Head and Neck Neoplasms; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016016:Proportional Hazards Models; D062085:RNA, Long Noncoding; D000077195:Squamous Cell Carcinoma of Head and ... | Scientific reports | 2,022 | D062085:RNA, Long Noncoding; C010223:N-methyladenosine; D000241:Adenosine |
Are male nurses sexually harassed? A cross-sectional study in the Greek Health System. | BACKGROUND
The #MeToo and #Times Up movements have put a global spotlight on the phenomenon of sexual harassment in healthcare. Yet, most studies have explored sexual harassment among female professionals. This study departs from current research practices and investigates the frequency of sexual harassment in male nur... | 10.1186/s12912-021-00656-6 | 34,372,829 | BMC nursing | 2,021 | ||
Endophytic microbes Bacillus sp. LZR216-regulated root development is dependent on polar auxin transport in Arabidopsis seedlings. | Endophytic microbes Bacillus sp. LZR216 isolated from Arabidopsis root promoted Arabidopsis seedlings growth. It may be achieved by promoting the lateral root growth and inhibiting the primary root elongation. Plant roots are colonized by an immense number of microbes, including epiphytic and endophytic microbes. It wa... | 10.1007/s00299-015-1766-0 | 25,700,982 | D017360:Arabidopsis; D029681:Arabidopsis Proteins; D001407:Bacillus; D001692:Biological Transport; D060026:Endophytes; D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids; D026901:Membrane Transport Proteins; D010802:Phylogeny; D018517:Plant Roots; D030821:Plants, Genetically Modified; D036226:Seedlin... | Plant cell reports | 2,015 | D029681:Arabidopsis Proteins; D007210:Indoleacetic Acids; D026901:Membrane Transport Proteins; C116363:PIN1 protein, Arabidopsis; C117013:PIN2 protein, Arabidopsis; C449300:PIN3 protein, Arabidopsis |
Eprinomectin antiparasitic affects survival, reproduction and behavior of Folsomia candida biomarker, and its toxicity depends on the type of soil. | The objective of this study was to evaluate the toxicity of the antiparasitic agent eprinomectin in two subtropical soils, using ecotoxicological lethality, reproduction and avoidance behavior tests with springtails (Folsomia candida). Eprinomectin concentrations were 0 (control), 0.5, 1, 2, 4, 8, 12, 16 and 20 mg kg-1... | 10.1016/j.etap.2019.103262 | 31,634,705 | D000818:Animals; D000977:Antiparasitic Agents; D001181:Arthropods; D001362:Avoidance Learning; D001522:Behavior, Animal; D015415:Biomarkers; D007559:Ivermectin; D012098:Reproduction; D012987:Soil; D012989:Soil Pollutants | Environmental toxicology and pharmacology | 2,019 | D000977:Antiparasitic Agents; D015415:Biomarkers; D012987:Soil; D012989:Soil Pollutants; D007559:Ivermectin; C101434:eprinomectin |
Side effects of therapy with prostaglandin E1 in infants with critical congenital heart disease. | The case reports of 492 infants with critical congenital cardiac disease treated with prostaglandin E1 (PGE1) were reviewed to determine the nature and incidence of intercurrent medical events. Forty-three percent of the infants had at least one such event, but only half of these were related to PGE1 and the majority r... | 10.1161/01.cir.64.5.893 | 7,285,304 | D001424:Bacterial Infections; D002319:Cardiovascular System; D002490:Central Nervous System; D003490:Cyanosis; D003968:Diarrhea, Infantile; D004211:Disseminated Intravascular Coagulation; D005260:Female; D006330:Heart Defects, Congenital; D006801:Humans; D006996:Hypocalcemia; D007003:Hypoglycemia; D007231:Infant, Newbo... | Circulation | 1,981 | D011458:Prostaglandins E |
Action of intracellular IL-1Ra (Type 1) is independent of the IL-1 intracellular signalling pathway. | The balance between IL-1 and its naturally occurring inhibitor IL-1 receptor antagonist (IL-1ra) is critical in determining the inflammatory response. Four splice variants of the IL-1ra gene have been identified; one secreted (sIL-1ra) and three intracellular (icIL-1ra1-3). The biological roles of the intracellular iso... | 10.1016/j.cyto.2006.02.003 | 16,564,702 | D000255:Adenosine Triphosphate; D017398:Alternative Splicing; D002478:Cells, Cultured; D004721:Endoplasmic Reticulum; D004730:Endothelium, Vascular; D006367:HeLa Cells; D006801:Humans; D007249:Inflammation; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D016209:Interleukin-8; D011401:Promoter... | Cytokine | 2,006 | C507763:IL1RN protein, human; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D016209:Interleukin-8; C546468:P2RX7 protein, human; D018048:Receptors, Purinergic P2; D058486:Receptors, Purinergic P2X7; D012795:Sialoglycoproteins; D000255:Adenosine Triphosphate |
Estrous and endocrine responses of lactating Holsteins to forced ventilation during summer. | Fourteen lactating and cycling Holsteins in each of two summers were assigned randomly to pens in a free-stall barn either with or without overhead fans to study the effect of fan cooling on certain endocrine and behavioral responses during the estrous cycle. After an adjustment period of 8 d in the first summer and 21... | 10.3168/jds.S0022-0302(93)77363-4 | 8,445,097 | D000818:Animals; D001831:Body Temperature; D002406:Catheterization, Peripheral; D002417:Cattle; D015237:Dinoprost; D004971:Estrus; D005260:Female; D006799:Housing, Animal; D007774:Lactation; D007986:Luteinizing Hormone; D011374:Progesterone; D012621:Seasons; D014691:Ventilation | Journal of dairy science | 1,993 | D011374:Progesterone; D007986:Luteinizing Hormone; D015237:Dinoprost |
Evaluation of current errors within the administration of phosphodiesterase-5 inhibitors after more than 10 years of use. | OBJECTIVE
To detect current errors within the administration of phosphodiesterase type 5 inhibitors (PDE5is) and evaluate and elucidate what percentage of patients could be recovered for oral therapy with different subtypes of PDE5is through a re-education program.
METHODS
Two hundred fifty patients remitted to the a... | 24,745,797 | D000284:Administration, Oral; D000328:Adult; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D007172:Erectile Dysfunction; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008508:Medication Errors; D008875:Middle Aged; D010353:Patient Education as T... | Urology | 2,014 | D058986:Phosphodiesterase 5 Inhibitors | |
Enhancement of face recognition learning in patients with brain injury using three cognitive training procedures. | Twenty patients with impairments of face recognition, in the context of a broader pattern of cognitive deficits, were administered three new training procedures derived from contemporary theories of face processing to enhance their learning of new faces: semantic association (being given additional verbal information a... | 10.1080/09602010701419485 | 18,350,413 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001930:Brain Injuries; D015928:Cognitive Behavioral Therapy; D005145:Face; D005260:Female; D006801:Humans; D007858:Learning; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual; D010775:P... | Neuropsychological rehabilitation | 2,008 | |
The Bacon Chow study: maternal supplementation and infant growth. | The effect of maternal supplementation during both gestation and lactation on infant growth from birth to 12 mth was investigated in the double-blind, randomly allocated control trial conducted in Taiwan by the late Bacon F. Chow. The supplement was a milk-based formula providing 800 kcal and 40 g protein daily. The pl... | 10.1016/0378-3782(83)90104-4 | 6,365,516 | D000328:Adult; D000704:Analysis of Variance; D000886:Anthropometry; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D005527:Food, Fortified; D006128:Growth; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007774:Lact... | Early human development | 1,983 | |
Topological events on the lines of circular polarization in nonparaxial vector optical fields. | In nonparaxial vector optical fields, the following topological events are shown to occur in apparent violation of charge conservation: as one translates the observation plane along a line of circular polarization (a C line), the points on the line (C points) are seen to change not only the signs of their topological c... | 10.1364/OL.42.000611 | 28,146,540 | Optics letters | 2,017 | ||
Virtual Bronchoscopy Planner and Radial-EBUS Guided Biopsy for Organizing Pneumonia Diagnosis. | BACKGROUND
The diagnosis of organizing pneumonia (OP) often requires histological confirmation. The aim of this retrospective study was to evaluate the diagnostic yield and complication rate of radial endobronchial ultrasound (r-EBUS) for OP.
METHODS
All patients who had r-EBUS as a first diagnostic procedure for a p... | 10.3390/jcm11010104 | 35,011,844 | Journal of clinical medicine | 2,021 | ||
Can performance on daily activities discriminate between older adults with normal cognitive function and those with mild cognitive impairment? | OBJECTIVES
To examine whether preclinical disability in performance of cognitively focused instrumental activity of daily living (C-IADL) tasks can discriminate between older adults with normal cognitive function and those with mild cognitive impairment (MCI) and, secondarily, to determine the two tasks with the strong... | 10.1111/jgs.12878 | 24,890,517 | D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition; D060825:Cognitive Dysfunction; D003430:Cross-Sectional Studies; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D008875:Middle Aged | Journal of the American Geriatrics Society | 2,014 | |
Hard Enough to Manage My Emotions: How Hardiness Moderates the Relationship Between Emotional Demands and Exhaustion. | The frequency of conflicts with patients' families is one of the main contributors to the amount of emotional demands that healthcare professionals must tackle to prevent the occurrence of burnout symptoms. On the other hand, research evidence suggests that hardiness could enable healthcare professionals to handle thei... | 10.3389/fpsyg.2020.01194 | 32,625,138 | Frontiers in psychology | 2,020 | ||
Minimizing injury rates in soccer through preselection of players by somatotypes. | Incidence and types of injuries were investigated among 180 Nigerian soccer players selected from 6 clubs by a stratified random technique on the basis of somatotypes. The purpose was to identify physique types that are most prone to common injuries in soccer, in the groups during an 8-week duration of intensive traini... | 7,934,013 | D001265:Athletic Injuries; D006801:Humans; D008297:Male; D012916:Soccer; D013008:Somatotypes | The Journal of sports medicine and physical fitness | 1,994 | ||
Physiological interpretation of the skewness of indicator-dilution curves; theoretical considerations and a practical application. | Indicator-dilution curves can be interpreted and analysed by describing the system between injection- and sampling site with a physical model. Till now mainly compartmental and distributed models have been investigated. One feature of distributed models is the possibility to interpret skewness or asymmetry of the curve... | 10.1007/BF01908149 | 6,385,958 | D002196:Capillaries; D006439:Hemodynamics; D006801:Humans; D007201:Indicator Dilution Techniques; D011654:Pulmonary Edema; D013223:Statistics as Topic | Basic research in cardiology | 1,984 | |
Optic Disc Classification by Deep Learning versus Expert Neuro-Ophthalmologists. | OBJECTIVE
To compare the diagnostic performance of an artificial intelligence deep learning system with that of expert neuro-ophthalmologists in classifying optic disc appearance.
METHODS
The deep learning system was previously trained and validated on 14,341 ocular fundus photographs from 19 international centers. T... | 10.1002/ana.25839 | 32,621,348 | D000328:Adult; D000368:Aged; D000077321:Deep Learning; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008875:Middle Aged; D000072163:Ophthalmologists; D009898:Optic Disk; D012680:Sensitivity and Specificity | Annals of neurology | 2,020 | |
Cholesterol-dependent modulation of the toxicity of HIV-1 coat protein gp120 in human neuroblastoma cells. | The human immunodeficiency virus type 1 (HIV-1) coat glycoprotein gp120 binds to its (co)receptors and orchestrates cell entry by the direct fusion of viral and target cell membranes. Here, we modulated membrane fluidity of human neuroblastoma CHP100 cells by modulating their cholesterol content, and investigated the a... | 10.1046/j.1471-4159.2002.01072.x | 12,354,292 | D001094:Arachidonate 5-Lipoxygenase; D016718:Arachidonic Acid; D002118:Calcium; D016923:Cell Death; D002784:Cholesterol; D004789:Enzyme Activation; D015699:HIV Envelope Protein gp120; D015497:HIV-1; D006801:Humans; D007424:Intracellular Fluid; D008560:Membrane Fluidity; D008928:Mitochondria; D009336:Necrosis; D009447:N... | Journal of neurochemistry | 2,002 | D015699:HIV Envelope Protein gp120; D019718:Receptors, CXCR4; D016718:Arachidonic Acid; D002784:Cholesterol; D001094:Arachidonate 5-Lipoxygenase; D011451:Prostaglandin-Endoperoxide Synthases; D002118:Calcium |
Perceived causes of adverse pregnancy outcomes and remedies adopted by Kalenjin women in rural Kenya. | BACKGROUND
There have been few studies about the basis on which women in developing regions evaluate and choose traditional rather than western maternal care. This qualitative study explores the socio-cultural perceptions of complications associated with pregnancy and childbirth and how these perceptions influence mate... | 10.1186/s12884-018-2041-5 | 30,340,547 | D000293:Adolescent; D000328:Adult; D003469:Culture; D004032:Diet; D015444:Exercise; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007398:Interpersonal Relations; D007407:Interviews as Topic; D007630:Kenya; D008875:Middle Aged; D008880:Midwifery; D010465:Perception; D011247:Pregnancy; D... | BMC pregnancy and childbirth | 2,018 | |
Chinese and Korean characters engage the same visual word form area in proficient early Chinese-Korean bilinguals. | A number of recent studies consistently show an area, known as the visual word form area (VWFA), in the left fusiform gyrus that is selectively responsive for visual words in alphabetic scripts as well as in logographic scripts, such as Chinese characters. However, given the large difference between Chinese characters ... | 10.1371/journal.pone.0022765 | 21,818,386 | D044466:Asian People; D001931:Brain Mapping; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D019303:Multilingualism; D010775:Photic Stimulation; D013702:Temporal Lobe; D014796:Visual Perception; D055815:Young Adult | PloS one | 2,011 | |
Restorative treatment decisions from bitewing radiographs--performance of dental epidemiologists and general dental practitioners. | The object of the study was to compare the performance of a group of eight trained and standardized dental epidemiologists making restorative treatment decisions with that of a group of 20 general dental practitioners. Both groups read the same set of 15 pairs of simulated bitewing radiographs. For each approximal toot... | 10.1111/j.1600-0528.1996.tb00823.x | 8,654,028 | D001641:Bicuspid; D002983:Clinical Competence; D003657:Decision Making; D003731:Dental Caries; D003793:Dental Restoration, Permanent; D004813:Epidemiology; D005792:General Practice, Dental; D006801:Humans; D016013:Likelihood Functions; D008963:Molar; D010818:Practice Patterns, Physicians'; D012372:ROC Curve; D016300:Ra... | Community dentistry and oral epidemiology | 1,996 | |
Surgical treatment for total root avulsion type brachial plexus injuries by neurotization: a prospective comparison study between total and hemicontralateral C7 nerve root transfer. | PURPOSE
We conducted a clinical study to evaluate the effects of neurotization, especially comparing the total contralateral C7 (CC7) root transfer to hemi-CC7 transfer, on total root avulsion brachial plexus injuries (BPI).
METHODS
Forty patients who received neurotization for BPI were enrolled in this prospective s... | 10.1002/micr.22148 | 23,913,440 | D000293:Adolescent; D000328:Adult; D001917:Brachial Plexus; D005260:Female; D006801:Humans; D008297:Male; D016067:Nerve Transfer; D011446:Prospective Studies; D011843:Radiculopathy; D020127:Recovery of Function; D055815:Young Adult | Microsurgery | 2,014 | |
T reticular interneurons: a class of serially repeating cells in the zebrafish hindbrain. | We describe a class of reticular neurons, named T interneurons after the branching pattern of their axons, in young larvae of the zebrafish Brachydanio rerio. The cells were identified by filling them with HRP from application sites within the CNS. A serially repeating set of about ten such neurons is present in a long... | 10.1002/cne.902330306 | 3,980,775 | D000818:Animals; D003391:Cranial Nerves; D005399:Fishes; D006054:Goldfish; D007395:Interneurons; D009046:Motor Neurons; D012154:Reticular Formation; D013045:Species Specificity | The Journal of comparative neurology | 1,985 | |
Linking fat intake, the intestinal microbiome, and necrotizing enterocolitis in premature infants. | Components of diet, including the total amounts and specific types of fat, affect the composition of the intestinal microbiome in both animal models and cohort studies of humans. Amounts of total fat and specific fatty acids (FA) are some of the most variable nutritional components of breast milk. Evaluations of the mi... | 10.1038/pr.2014.155 | 25,303,279 | D004041:Dietary Fats; D064806:Dysbiosis; D020345:Enterocolitis, Necrotizing; D041981:Gastrointestinal Tract; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D064307:Microbiota; D051197:Toll-Like Receptor 4 | Pediatric research | 2,015 | D004041:Dietary Fats; D051197:Toll-Like Receptor 4 |
Clinical signs and risk factors associated with pneumonia in children admitted to Goroka Hospital, Papua New Guinea. | This study examined the clinical signs and symptoms in 897 children aged under 5 years presenting with pneumonia to Goroka Hospital in the highlands of Papua New Guinea between June 1982 and July 1985. The usefulness of the signs in predicting severity of disease was determined and risk factors for severe disease were ... | 10.1093/tropej/35.6.295 | 2,607,582 | D000900:Anti-Bacterial Agents; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006764:Hospitals, Community; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009752:Nutritional Status; D010219:Papua New Guinea; D011014:Pneumonia; D012307:Risk Factors | Journal of tropical pediatrics | 1,989 | D000900:Anti-Bacterial Agents |
Risk management--an inspector calls. | Following recent health and safety legislation, the health service has been told to put its house in order. Some hospitals are moving fast, but others still have their heads in the sand bucket, reports Barbara Millar. | 10,125,796 | D016272:Occupational Health; D012308:Risk Management; D013222:State Medicine; D006113:United Kingdom | The Health service journal | 1,993 | ||
Response of cultured human pulmonary artery endothelial cells to endotoxin. | Endotoxemia is the leading cause of the adult respiratory distress syndrome. The effects of endotoxin on pulmonary endothelium, both in vivo and in culture, are diverse and complicated, and vary between species and cellular origin. Species such as sheep and cows are particularly sensitive to endotoxin, whereas rats and... | 10.1152/ajplung.1995.268.2.L239 | 7,864,145 | D002478:Cells, Cultured; D004730:Endothelium, Vascular; D004731:Endotoxins; D004926:Escherichia coli; D006801:Humans; D011453:Prostaglandins; D011651:Pulmonary Artery | The American journal of physiology | 1,995 | D004731:Endotoxins; D011453:Prostaglandins |
Flexor digitorum profundus tendon excursions during controlled motion after flexor tendon repair in zone II: a prospective clinical study. | Intratendinous metal markers were used to study flexor digitorum profundus tendon excursions during early controlled motion with dynamic flexion traction and to evaluate their significance for results after flexor tendon repair in zone II. The mean excursion was 1 mm along the middle phalanx and 5.6 mm along the proxim... | 10.1016/0363-5023(92)90127-b | 1,538,093 | D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005384:Finger Joint; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies; D011859:Radiography; D016059:Range of Motion, Articular; D013708:Tendon Injuries; D013710:Tendons; D013997:Time Factors | The Journal of hand surgery | 1,992 | |
Transactional sex among men who have sex with men in Latin America: economic, sociodemographic, and psychosocial factors. | OBJECTIVES
We assessed factors associated with engagement in transactional sex among men who have sex with men recruited from one of the largest Internet sites for men seeking social or sexual interactions with other men in Latin America.
METHODS
We constructed multilevel logistic regression models to analyze factors... | 10.2105/AJPH.2014.302402 | 25,790,381 | D000328:Adult; D054523:Adult Survivors of Child Abuse; D000367:Age Factors; D015658:HIV Infections; D018451:Homosexuality, Male; D006801:Humans; D020407:Internet; D007398:Interpersonal Relations; D007843:Latin America; D008297:Male; D012111:Residence Characteristics; D012725:Sexual Behavior; D012749:Sexually Transmitte... | American journal of public health | 2,015 | |
Successful engraftment of sibling cord-blood stem cell transplantation in a child with acute promyelocytic leukemia. | Cord blood stem cell transplantation (CBSCT) was performed on a patient with acute promyelocytic leukemia. The patient was a boy 3 years and 8 months old, who had shown complete remission following treatment with intensive chemotherapy. However, after the final course of consolidation chemotherapy, chromosome analysis ... | 10.1016/0925-5710(96)00483-5 | 8,923,791 | D000328:Adult; D001771:Blood Banks; D001772:Blood Cell Count; D002675:Child, Preschool; D005260:Female; D005312:Fetal Blood; D016179:Granulocyte Colony-Stimulating Factor; D018380:Hematopoietic Stem Cell Transplantation; D006650:Histocompatibility Testing; D006801:Humans; D007231:Infant, Newborn; D007564:Japan; D015473... | International journal of hematology | 1,996 | D016179:Granulocyte Colony-Stimulating Factor |
Potential therapeutic targets and the role of technology in developing novel cannabinoid drugs from cyanobacteria. | Cyanobacteria find several applications in pharmacology as potential candidates for drug design. The need for new compounds that can be used as drugs has always been on the rise in therapeutics. Cyanobacteria have been identified as promising targets of research in the quest for new pharmaceutical compounds as they can... | 10.1016/j.biopha.2016.06.052 | 27,416,557 | D020811:Biomedical Technology; D002186:Cannabinoids; D000458:Cyanobacteria; D015195:Drug Design; D058990:Molecular Targeted Therapy; D043882:Receptors, Cannabinoid | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie | 2,016 | D002186:Cannabinoids; D043882:Receptors, Cannabinoid |
Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. | PS-341, also known as Velcade or Bortezomib, represents a new class of anticancer drugs which has been shown to potently inhibit the growth and/or progression of human cancers, including head and neck squamous cell carcinoma (HNSCC). Although it has been logically hypothesized that NF-kappaB is a major target of PS-341... | 10.1128/MCB.24.22.9695-9704.2004 | 15,509,775 | D000970:Antineoplastic Agents; D017209:Apoptosis; D001897:Boronic Acids; D000069286:Bortezomib; D002294:Carcinoma, Squamous Cell; D020169:Caspases; D045744:Cell Line, Tumor; D004721:Endoplasmic Reticulum; D020869:Gene Expression Profiling; D006258:Head and Neck Neoplasms; D006801:Humans; D016328:NF-kappa B; D020411:Oli... | Molecular and cellular biology | 2,004 | D000970:Antineoplastic Agents; D001897:Boronic Acids; D016328:NF-kappa B; D011480:Protease Inhibitors; D061988:Proteasome Inhibitors; D011719:Pyrazines; D017382:Reactive Oxygen Species; D000069286:Bortezomib; D020169:Caspases; D046988:Proteasome Endopeptidase Complex; C061553:ATP dependent 26S protease |
An unusual presentation of non-Hodgkin's lymphoma (NHL) in a child. | A rare case of a primary early T-cell non-Hodgkin's lymphoma (NHL) in the bronchus of a 10 year old boy is presented. Although histological examination of the biopsied material was compatible with the diagnosis of NHL or carcinoma, the use of monoclonal antibodies showed it to be an early T-cell NHL and not carcinoma. ... | 3,709,824 | D000911:Antibodies, Monoclonal; D000971:Antineoplastic Combined Chemotherapy Protocols; D001984:Bronchial Neoplasms; D001999:Bronchoscopy; D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D008223:Lymphoma; D008297:Male | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology | 1,986 | D000911:Antibodies, Monoclonal | |
Elevated CXCL-8 expression in bronchoalveolar lavage correlates with disease severity in patients with acute respiratory distress syndrome resulting from tuberculosis. | BACKGROUND
Tuberculosis (TB) is a rare but known cause of acute respiratory distress syndrome (ARDS). The role of inflammatory cytokines in the progression of ARDS in TB patients is unknown.
OBJECTIVES
In this study we investigated the possible link between the levels of inflammatory cytokines in bronchoalveolar lava... | 10.1186/1476-9255-11-21 | 25,110,464 | Journal of inflammation (London, England) | 2,014 | ||
Air blood barrier phenotype correlates with alveolo-capillary O2 equilibration in hypobaric hypoxia. | The O2 diffusion limitation across the air blood barrier (DO2 and subcomponents Dm and Vc) was evaluated in 17 healthy participants exposed to hypobaric hypoxia (HA, 3840m, PIO2 ∼90mmHg). A 10% decrease in alveolar volume (VA) in all participants suggested the development of sub-clinical interstitial lung edema. In >80... | 10.1016/j.resp.2017.08.006 | 28,801,275 | D000328:Adult; D015824:Blood-Air Barrier; D004452:Echocardiography; D005260:Female; D006801:Humans; D000860:Hypoxia; D008297:Male; D008875:Middle Aged; D010100:Oxygen; D010313:Partial Pressure; D011653:Pulmonary Diffusing Capacity; D012123:Pulmonary Ventilation | Respiratory physiology & neurobiology | 2,017 | D010100:Oxygen |
K-ras mutation in sputum of patients with or without lung cancer. | K-ras mutation appears in about 60% of patients with non-small-cell lung cancer (NSCLC). This frequency and its presence in normal appearing tissues point to the potential of ras oncogene mutation to serve as a good biomarker. Using enriched PCR (EPCR), which enables the detection of one mutant allele in the presence o... | 9,027,615 | D000328:Adult; D000368:Aged; D004252:DNA Mutational Analysis; D011905:Genes, ras; D006801:Humans; D008171:Lung Diseases; D008175:Lung Neoplasms; D008875:Middle Aged; D009154:Mutation; D016133:Polymerase Chain Reaction; D013183:Sputum | Journal of cellular biochemistry. Supplement | 1,996 | ||
Implementation of clinical decision support in young children with acute gastroenteritis: a randomized controlled trial at the emergency department. | Acute gastroenteritis (AGE) is one of the most frequent reasons for young children to visit emergency departments (EDs). We aimed to evaluate (1) feasibility of a nurse-guided clinical decision support system for rehydration treatment in children with AGE and (2) the impact on diagnostics, treatment, and costs compared... | 10.1007/s00431-016-2819-2 | 27,933,399 | D000208:Acute Disease; D002675:Child, Preschool; D003661:Decision Support Techniques; D003681:Dehydration; D003967:Diarrhea; D004636:Emergency Service, Hospital; D005240:Feasibility Studies; D005260:Female; D005440:Fluid Therapy; D005759:Gastroenteritis; D019983:Guideline Adherence; D006801:Humans; D007223:Infant; D007... | European journal of pediatrics | 2,017 | |
Impact of uniaxial strain on the electronic and transport properties of monolayer α-GeTe. | Density functional theory calculations are performed to explore the electronic and transport properties of monolayer α-GeTe under uniaxial strain. It is found that monolayer α-GeTe has an indirect band gap of 1.75 eV and exhibits worthwhile anisotropy along with high electron mobility. The electron mobilities reach 197... | 10.1088/1361-6528/aba5b9 | 32,663,807 | Nanotechnology | 2,020 | ||
An evaluation of the environmental impact assessment practice in Uganda: challenges and opportunities for achieving sustainable development. | Environmental Impact Assessment (EIA) is a broad process that emerged from the National Environment Policy Act, 1970 in the U.S. Its primary objective is to generate information on the likely impacts of a project on all aspects of the environment and used in agency decision making and in the long run protect the enviro... | 10.1016/j.heliyon.2020.e04758 | 32,984,571 | Heliyon | 2,020 | ||
Support from healthcare professionals in empowering family carers to discuss advance care planning: A population-based survey. | BACKGROUND
Family carers have a prominent role in end-of-life care for seriously ill persons. However, most of the advance care planning literature is focused on the role of healthcare professionals.
AIMS
To investigate (1) what proportion of family carers discussed advance care planning with their relative and assoc... | 10.1177/02692163221135032 | 36,349,646 | D006801:Humans; D017028:Caregivers; D003430:Cross-Sectional Studies; D032722:Advance Care Planning; D003695:Delivery of Health Care; D011209:Power, Psychological | Palliative medicine | 2,023 | |
[Muscle fatigue and dyspnea]. | Calm breathing requires little effort on the part of the inspiratory muscles to overcome the elastic and non-elastic resistances of the chest-lung system. Spontaneous expiration is passive and does not engage the respiratory muscles. In the event of restriction or obstruction, however, there are changes in these two ty... | 10,189,900 | D004417:Dyspnea; D006801:Humans; D018763:Muscle Fatigue; D012132:Respiratory Muscles | Minerva medica | 1,998 | ||
Liver Transplantation After Hepatic Artery Infusion Pump Therapy: Single-Center Experience and Technical Considerations. | BACKGROUND
Hepatic artery infusion pump (HAIP) therapy has become increasingly commonplace in the treatment of intrahepatic tumors. When combined with standard chemotherapy, HAIP therapy demonstrates a higher response rate than chemotherapy alone. Biliary sclerosis is observed in up to 22 % of patients, for whom no tre... | 10.1245/s10434-023-13652-8 | 37,210,451 | D006801:Humans; D008297:Male; D005260:Female; D008875:Middle Aged; D006499:Hepatic Artery; D016031:Liver Transplantation; D012189:Retrospective Studies; D006498:Hepatectomy; D015918:Infusion Pumps, Implantable | Annals of surgical oncology | 2,023 | |
BIOMECHANICAL COMPARISON OF MEDIAL VERSUS LATERAL SIDED PLATING IN FEMORAL FRACTURES. | OBJECTIVE
The aim of the present study was to determine whether the side of application of the plate itself affects the mechanical stability of the fixation. The specific question addressed is whether or not a lateral or medial plate application is biomechanically better, for the treatment of distal diaphysis fractures... | 10.1590/1413-785220182604191645 | 30,210,258 | Acta ortopedica brasileira | 2,018 | ||
Unconventional features of C9ORF72 expanded repeat in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. | Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are devastating neurodegenerative diseases that form two ends of a complex disease spectrum. Aggregation of RNA binding proteins is one of the hallmark pathologic features of ALS and FTDL and suggests perturbance of the RNA metabolism in t... | 24,836,899 | D000690:Amyotrophic Lateral Sclerosis; D000073885:C9orf72 Protein; D042622:DNA Repeat Expansion; D004268:DNA-Binding Proteins; D057174:Frontotemporal Lobar Degeneration; D056726:Genetic Association Studies; D006801:Humans; D066263:Protein Aggregation, Pathological; D011506:Proteins; D012313:RNA; D016601:RNA-Binding Pro... | Neurobiology of aging | 2,014 | D000073885:C9orf72 Protein; C568651:C9orf72 protein, human; D004268:DNA-Binding Proteins; D011506:Proteins; D016601:RNA-Binding Proteins; D012313:RNA | |
Automatic purification of monoclonal antibodies. | Purification has become the rate limiting step in the development and production of protein-based products, especially for monoclonal antibodies. An example of a fully integrated low/medium pressure chromatograph is presented. The MabLab is driven by expert software and it characterizes an unknown antibody in about fiv... | 2,401,390 | D000818:Animals; D000911:Antibodies, Monoclonal; D001322:Autoanalysis; D002460:Cell Line; D002852:Chromatography, Ion Exchange; D051379:Mice; D012984:Software | Developments in biological standardization | 1,990 | D000911:Antibodies, Monoclonal | |
Changes in proximal femoral bone mineral density around a hydroxyapatite-coated hip joint arthroplasty. | OBJECTIVE
To present the results of a prospective analysis of proximal femoral bone mineral density changes around a hydroxyapatite-coated total hip joint replacement.
METHODS
14 patients with osteoarthritis of the hip were enrolled in the study and treated with an uncemented ABG prosthesis. Dual energy X-ray absorpt... | 10.1177/230949900301100111 | 12,810,972 | D015502:Absorptiometry, Photon; D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D015519:Bone Density; D020099:Coated Materials, Biocompatible; D017886:Durapatite; D005260:Female; D005269:Femur; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthr... | Journal of orthopaedic surgery (Hong Kong) | 2,003 | D020099:Coated Materials, Biocompatible; D017886:Durapatite |
Summary of track D: social science: research, policy and action. | SCOPE
This review summarizes the main issues discussed during Track D, which examined the societal impact of HIV/AIDS, and responses to the epidemic by individuals, families, communities and societies worldwide. Micro- and macrolevel issues addressed included the development, implementation and evaluation of programmes... | 8,970,719 | D003153:Community Health Services; D015658:HIV Infections; D006291:Health Policy; D006302:Health Services Research; D006801:Humans | AIDS (London, England) | 1,996 | ||
Iodine-catalyzed electrophilic substitution of indoles: Synthesis of (un)symmetrical diindolylmethanes with a quaternary carbon center. | A novel, versatile approach for the synthesis of unsymmetrical 3,3'-diindolylmethanes (DIMs) with a quaternary carbon center has been developed via iodine-catalyzed coupling of trifluoromethyl(indolyl)phenylmethanols with indoles. In contrast to previously reported methods, the new procedure is characterized by chemose... | 10.3762/bjoc.17.102 | 34,221,175 | Beilstein journal of organic chemistry | 2,021 |
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