title large_stringlengths 0 979 | abstract large_stringlengths 1 94.7k | doi large_stringlengths 0 71 | pmid int64 21 38.1M | mesh_terms large_stringlengths 0 1.47k | journal large_stringlengths 1 239 | pubdate int16 1.97k 2.02k | chemical_list large_stringlengths 0 1.47k |
|---|---|---|---|---|---|---|---|
Selective hydrolysis of hen egg white lysozyme at Asp-X peptide bonds promoted by oxomolybdate. | The activity of oxomolybdate(VI) towards hen egg white lysozyme (HEWL) was examined under physiological and slightly acidic pH conditions. Purely hydrolytic cleavage of HEWL in the presence of 10 to 100 mM of oxomolybdate(VI) after incubation at pH 5.0 and 60 °C for 2 to 7 days was observed in SDS-PAGE experiments. Fou... | 24,769,136 | D020816:Amino Acid Motifs; D000818:Animals; D002645:Chickens; D004527:Egg Proteins; D006868:Hydrolysis; D008982:Molybdenum; D009113:Muramidase; D059748:Proteolysis | Journal of inorganic biochemistry | 2,014 | D004527:Egg Proteins; D008982:Molybdenum; D009113:Muramidase | |
Genetic profiles of newly inbred Dahl/Iwai salt-sensitive and salt-resistant rats. | Dahl-Iwai salt-sensitive (S) and salt-resistant (R) rat strains were established as inbred strains at Brookhaven National Laboratory, NY, and were introduced into Eisai Co., Ltd., Japan, and designated DIS/Eis and DIR/Eis. To examine whether there are different allele distributions among the substrains of inbred Dahl S... | 9,160,789 | D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D004351:Drug Resistance; D005260:Female; D006973:Hypertension; D008297:Male; D011110:Polymorphism, Genetic; D051381:Rats; D011919:Rats, Inbred Strains; D012965:Sodium Chloride; D013045:Species Specificity | American journal of hypertension | 1,997 | D012965:Sodium Chloride | |
Irradiated polyglactin 910 (Vicryl Rapide) for placement of full-thickness skin grafts. | BACKGROUND
The "unsuture" technique originally reported with the use of fast-absorbing gut for the placement of full-thickness skin grafts has provided years of successful full-thickness graft placement without the need for suture removal.
OBJECTIVE
The objective was to explore another option for successful graft pla... | 10.2310/6350.2005.31313 | 16,336,892 | D001672:Biocompatible Materials; D020878:Device Removal; D006257:Head; D006801:Humans; D011098:Polyglactin 910; D016038:Skin Transplantation; D013536:Suture Techniques; D013537:Sutures; D014945:Wound Healing | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] | 2,005 | D001672:Biocompatible Materials; D011098:Polyglactin 910 |
Kirigami-Inspired Conducting Polymer Thermoelectrics from Electrostatic Recognition Driven Assembly. | Two-dimensional (2D) conducting polymers are expected to offer emergent topological, structural, and physical properties, which has become the "holy grail" for the development of plastic electronics. Here, we report the assembly of a free-floating metallic polymer layer, consisting of poly(3,4-ethylenedioxythiophene) c... | 10.1021/acsnano.8b02489 | 29,985,586 | ACS nano | 2,018 | ||
Medical Therapy of Acromegaly in Germany 2019 - Data from the German Acromegaly Registry. | CONTEXT
Acromegaly is a rare disease caused by excessive growth hormone (GH) secretion from pituitary adenomas in most cases. If neurosurgical therapy is contraindicated or not sufficient, medical therapy is the second line therapy.
OBJECTIVE
To describe current medical therapy in acromegaly.
DESIGN & METHODS
Retro... | 10.1055/a-1191-2437 | 32,604,431 | D000172:Acromegaly; D000328:Adult; D000077465:Cabergoline; D018491:Dopamine Agonists; D005260:Female; D005858:Germany; D019382:Human Growth Hormone; D006801:Humans; D007334:Insulin-Like Growth Factor I; D008297:Male; D008875:Middle Aged; D015282:Octreotide; D010456:Peptides, Cyclic; D012042:Registries; D012189:Retrospe... | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association | 2,021 | D018491:Dopamine Agonists; C583557:IGF1 protein, human; D010456:Peptides, Cyclic; C060347:lanreotide; D019382:Human Growth Hormone; D013004:Somatostatin; D007334:Insulin-Like Growth Factor I; D000077465:Cabergoline; C406545:pegvisomant; D015282:Octreotide |
Olfactory receptors are expressed in pancreatic β-cells and promote glucose-stimulated insulin secretion. | Olfactory receptors (ORs) mediate olfactory chemo-sensation in OR neurons. Herein, we have demonstrated that the OR chemo-sensing machinery functions in pancreatic β-cells and modulates insulin secretion. First, we found several OR isoforms, including OLFR15 and OLFR821, to be expressed in pancreatic islets and a β-cel... | 10.1038/s41598-018-19765-5 | 29,367,680 | D000818:Animals; D002460:Cell Line; D020869:Gene Expression Profiling; D005947:Glucose; D007150:Immunohistochemistry; D007328:Insulin; D050417:Insulin-Secreting Cells; D051379:Mice; D008810:Mice, Inbred C57BL; D012333:RNA, Messenger; D018035:Receptors, Odorant | Scientific reports | 2,018 | D007328:Insulin; C498563:Olfr256 protein, mouse; C000629271:Olfr821 protein, mouse; D012333:RNA, Messenger; D018035:Receptors, Odorant; D005947:Glucose |
Fostering Passion and Skills in Surgical Research Across the Medical Education Continuum: The Transplant Research, Education, and Engagement Group. | OBJECTIVE
We describe a multilevel, collaborative research group for trainees and faculty engaging in transplant surgery research within one institution.
DESIGN
Transplant Research, Education, and Engagement (TREE) was designed to develop trainees' research skills and foster enthusiasm in transplant surgery along the... | 10.1016/j.jsurg.2020.07.006 | 32,739,442 | D002983:Clinical Competence; D004501:Education, Medical; D006801:Humans; D008611:Mentors; D008824:Michigan; D016377:Organ Transplantation | Journal of surgical education | 2,021 | |
Integrated Bioinformatics and Validation Reveal IL1B and Its Related Molecules as Potential Biomarkers in Chronic Spontaneous Urticaria. | Background
The etiopathogenesis of chronic spontaneous urticaria (CSU) has not been fully understood, and there has been extensive interest in the interaction between inflammatory dermatosis and pyroptosis. This study intends to investigate the molecular mechanism of pyroptosis-related genes in CSU via bioinformatic wa... | 10.3389/fimmu.2022.850993 | 35,371,000 | D015415:Biomarkers; D000080223:Chronic Urticaria; D019295:Computational Biology; D006801:Humans; D053583:Interleukin-1beta; D035683:MicroRNAs; D062105:Molecular Docking Simulation | Frontiers in immunology | 2,022 | D015415:Biomarkers; C508585:IL1B protein, human; D053583:Interleukin-1beta; D035683:MicroRNAs |
[Human and Influenza - an Overview]. | Influenza is an acute viral disease with involvement of the respiratory tract. It can be life-threatening. New types of influenza viruses can spread globally and cause influenza pandemics with exalted case numbers. The knowledge about epidemiology, preventive hygiene and vaccination, diagnostic, therapy and clinics are... | 10.1055/s-0043-105850 | 29,514,356 | D000328:Adult; D006801:Humans; D007251:Influenza, Human; D009439:Neuraminidase; D058873:Pandemics; D014611:Vaccination | Pneumologie (Stuttgart, Germany) | 2,018 | D009439:Neuraminidase |
Calcification in Pulmonary Heart Valve Tissue Engineering: A Systematic Review and Meta-Analysis of Large-Animal Studies. | Tissue-engineered heart valves (TEHVs) are emerging alternatives to current valve prostheses and prospectively a lifelong replacement. Calcification, a pathological complication for biological protheses, has been reported in preclinical TEHV studies. Systematic analysis of its occurrence is missing. This review aims to... | 10.1016/j.jacbts.2022.09.009 | 37,325,410 | JACC. Basic to translational science | 2,023 | ||
Force output in giant-slalom skiing: A practical model of force application effectiveness. | Alpine ski racers require diverse physical capabilities. While enhanced force production is considered key to high-level skiing, its relevance is convoluted. The aims of this study were to i) clarify the association between performance path length and velocity, ii) test the importance of radial force, and iii) explore ... | 10.1371/journal.pone.0244698 | 33,444,398 | D000054:Acceleration; D000328:Adult; D056352:Athletes; D054874:Athletic Performance; D001696:Biomechanical Phenomena; D006801:Humans; D012865:Skiing; D055815:Young Adult | PloS one | 2,021 | |
Effects of thalamic infarction on the structural and functional connectivity of the ipsilesional primary somatosensory cortex. | OBJECTIVES
To identify regions causally influenced by thalamic stroke by measuring white matter integrity, cortical volume, and functional connectivity (FC) among patients with thalamic infarction (TI) and to determine the association between structural/functional alteration and somatosensory dysfunction.
METHODS
Thi... | 10.1007/s00330-019-06068-0 | 30,840,103 | D016880:Anisotropy; D002544:Cerebral Infarction; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D059906:Neuroimaging; D011446:Prospective Studies; D013003:Somatosensory Cortex; D020521:Stroke; D013788:Thalamus | European radiology | 2,019 | |
Parasexual and Sexual Reproduction in Arbuscular Mycorrhizal Fungi: Room for Both. | Arbuscular mycorrhizal fungi (AMF) harbor thousands of nuclei in a large syncytium at all times. Although mating processes have not been observed in AMF, their cells and genomes show many signatures of sexual reproduction. Here, we describe how some of these signatures could also arise from parasexual processes in thes... | 10.1016/j.tim.2020.03.013 | 32,360,097 | D001487:Basidiomycota; D002176:Candida albicans; D016681:Genome, Fungal; D008540:Meiosis; D038821:Mycorrhizae; D010944:Plants; D012100:Reproduction, Asexual | Trends in microbiology | 2,020 | |
Simultaneous pancreas and kidney transplantation: current trends and future directions. | PURPOSE OF REVIEW
Important trends are being observed in pancreas transplantation in the USA. We will describe recent trends in simultaneous pancreas kidney (SPK) transplantation related to immunosuppression, treatment of rejection, and transplantation for patients of advanced age and C-peptide positive diabetes.
REC... | 10.1097/MOT.0000000000000146 | 25,565,444 | D000818:Animals; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation; D016035:Pancreas Transplantation | Current opinion in organ transplantation | 2,015 | |
[Analysis on ecological factors and active components content of wild Dipsacus asper in Chongqing Wulong district]. | An HPLC method was developed for the determination of iridoid glycosides (loganin acid, loganin, sweroside) and saponins (asperosaponin Ⅵ) in the wild Dipsacus asper. A total of 108 samples consecutive growing 12 month were collected in 9 plots in Wulong district of Chongqing. Subsequent analysis of the content of loga... | 10.19540/j.cnki.cjcmm.20180404.002 | 30,111,025 | D002851:Chromatography, High Pressure Liquid; D049917:Dipsacaceae; D004365:Drugs, Chinese Herbal; D017753:Ecosystem | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | 2,018 | D004365:Drugs, Chinese Herbal |
The mixing effect of organic cations on the structural, electronic and optical properties of FAxMA1-xPbI3 perovskites. | Organic-inorganic hybrid perovskites as new emerging functional materials stand out from numerous photovoltaic materials thanks to the unprecedentedly rapid improvement of their power conversion efficiency within a short period. To explore potentially more efficient photovoltaic candidates, the structural and electroni... | 10.1039/c7cp06608b | 29,231,219 | Physical chemistry chemical physics : PCCP | 2,018 | ||
Y chromosome instability in testicular cancer. | Approximately 15-25% of male infertility cases carry extensive azoospermic factor (AZF) deletions. Moreover, about 80% of Finnish testicular germ cell tumors (TGCT) and about 23-25% of TGCTs from other geographic regions carry short and interstitial AZF deletions. In infertility cases the AZF deficiency occurs in the g... | 10.1016/j.mrrev.2005.12.001 | 16,483,836 | D043171:Chromosomal Instability; D041322:Chromosomes, Human, Y; D005387:Finland; D017353:Gene Deletion; D056426:Genetic Loci; D006801:Humans; D007248:Infertility, Male; D008297:Male; D029589:Seminal Plasma Proteins; D013736:Testicular Neoplasms | Mutation research | 2,006 | D029589:Seminal Plasma Proteins |
External pressure of undisturbed left ventricle. | We evaluated the contribution of the thorax and the undisturbed pericardium to the external pressure of the euvolemic left ventricle in thirteen anesthetized dogs. Left ventricular (LV) end-diastolic pressure (EDP) in the euvolemic state was 7 +/- 2 mmHg initially and increased to 10 +/- 2 mmHg after the chest and peri... | 10.1152/ajpheart.1990.258.4.H1079 | 2,330,995 | D000818:Animals; D004285:Dogs; D006321:Heart; D006352:Heart Ventricles; D008955:Models, Cardiovascular; D010496:Pericardium; D011312:Pressure; D013318:Stroke Volume; D013909:Thorax | The American journal of physiology | 1,990 | |
The deleterious effects of bed rest on human skeletal muscle fibers are exacerbated by hypercortisolemia and ameliorated by dietary supplementation. | Prolonged inactivity associated with bed rest in a clinical setting or spaceflight is frequently associated with hypercortisolemia and inadequate caloric intake. Here, we determined the effect of 28 days of bed rest (BR); bed rest plus hypercortisolemia (BRHC); and bed rest plus essential amino acid (AA) and carbohydra... | 10.1152/ajpcell.00573.2006 | 17,409,123 | D000328:Adult; D000601:Amino Acids, Essential; D001510:Bed Rest; D002908:Chronic Disease; D003480:Cushing Syndrome; D019422:Dietary Sucrose; D006801:Humans; D006854:Hydrocortisone; D008297:Male; D009119:Muscle Contraction; D018656:Muscle Fibers, Fast-Twitch; D018657:Muscle Fibers, Slow-Twitch; D053580:Muscle Strength; ... | American journal of physiology. Cell physiology | 2,007 | D000601:Amino Acids, Essential; D019422:Dietary Sucrose; C007133:hydrocortisone hemisuccinate; D006854:Hydrocortisone |
Numeracy skills of undergraduate entry level nurse, midwife and pharmacy students. | BACKGROUND
The ability of healthcare professionals to perform basic numeracy and therefore dose calculations competently is without question. Research has primarily focused on nurses, and to a lesser extent doctors, ability to perform this function with findings highlighting poor aptitude. Studies involving pharmacists... | 10.1016/j.nepr.2012.01.004 | 22,305,744 | D001291:Attitude of Health Personnel; D002983:Clinical Competence; D054796:Drug Dosage Calculations; D004508:Education, Nursing, Baccalaureate; D004521:Educational Measurement; D006801:Humans; D008433:Mathematics; D008880:Midwifery; D015402:Nursing Education Research; D015403:Nursing Evaluation Research; D013338:Studen... | Nurse education in practice | 2,012 | |
Development of an immune-nutritional prognostic index in patients with muscle-infiltrating bladder cancer candidates for radical cystectomy. | INTRODUCTION
Muscle-infiltrating bladder tumor (MIBT) has a recurrence-free survival (RFS) of 50% at 5 years. Although neoadjuvant chemotherapy (NCT) has increased it by 8%, which group of patients benefits the most from this treatment remains unclear.
OBJECTIVE
Evaluate the prognostic value of immune-nutritional sta... | 10.1016/j.acuroe.2022.09.001 | 37,078,843 | D006801:Humans; D011379:Prognosis; D015653:Cystectomy; D015596:Nutrition Assessment; D012189:Retrospective Studies; D001749:Urinary Bladder Neoplasms; D009132:Muscles | Actas urologicas espanolas | 2,023 | |
In vivo splicing products of the rabbit beta-globin pre-mRNA. | Analysis of the rabbit beta-globin transcripts present in the steady-state RNA population of fetal liver reveals that there is no strict order in the removal of the two introns from the pre-mRNA, though IVS1 seems to be preferentially eliminated first. The population of RNA molecules contains, among other splicing prod... | 10.1016/0092-8674(84)90466-5 | 6,096,012 | D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004274:DNA, Recombinant; D004720:Endonucleases; D004722:Endoribonucleases; D005914:Globins; D007700:Kinetics; D009693:Nucleic Acid Hybridization; D009694:Nucleic Acid Precursors; D012322:RNA Precursors; D012326:RNA Splicing; D012333:RNA, Messenger; D0... | Cell | 1,984 | D004274:DNA, Recombinant; D009694:Nucleic Acid Precursors; D012322:RNA Precursors; D012333:RNA, Messenger; D005914:Globins; D004720:Endonucleases; D004722:Endoribonucleases; D016914:Ribonuclease H; D015719:Single-Strand Specific DNA and RNA Endonucleases |
Design considerations for efficient and effective microarray studies. | This article describes the theoretical and practical issues in experimental design for gene expression microarrays. Specifically, this article 1) discusses the basic principles of design (randomization, replication, and blocking) as they pertain to microarrays, and 2) provides some general guidelines for statisticians ... | 10.1111/j.0006-341x.2003.00096.x | 14,969,460 | D001699:Biometry; D006801:Humans; D008957:Models, Genetic; D015233:Models, Statistical; D015588:Observer Variation; D020411:Oligonucleotide Array Sequence Analysis; D012313:RNA; D015203:Reproducibility of Results; D012107:Research Design | Biometrics | 2,003 | D012313:RNA |
Prostaglandin synthase activity of fetal sheep cotyledons at 122 days of gestation and term: expression of prostaglandin synthetic capacity in fetal cotyledonary tissue near labor is location-dependent. | An activity assay is described quantification of prostaglandin synthase (PGHS) in sheep placental cotyledon under initial velocity conditions through measurement of the stable product prostaglandin E2 (PGE2). The effects of temperature, time, and substrate concentration on initial reaction velocity, and lipoxygenase an... | 10.1095/biolreprod52.4.737 | 7,779,995 | D000818:Animals; D016718:Arachidonic Acid; D002855:Chromatography, Thin Layer; D015232:Dinoprostone; D005260:Female; D005865:Gestational Age; D007743:Labor, Obstetric; D008084:Lipoxygenase; D008861:Microsomes; D010920:Placenta; D011247:Pregnancy; D011451:Prostaglandin-Endoperoxide Synthases; D012756:Sheep; D013696:Temp... | Biology of reproduction | 1,995 | D016718:Arachidonic Acid; D008084:Lipoxygenase; D011451:Prostaglandin-Endoperoxide Synthases; D015232:Dinoprostone |
Prognostic value of dipyridamole stress echocardiography in hypertensive patients with left ventricular hypertrophy, chest pain and resting electrocardiographic repolarization abnormalities. | BACKGROUND
Hypertension is a major cardiovascular risk factor in the development of coronary artery disease (CAD); therefore, evaluating the presence of CAD is a primary clinical goal. However, the noninvasive tests that are commonly used have poor diagnostic specificity, particularly in patients with left ventricular ... | 11,381,279 | D000368:Aged; D002637:Chest Pain; D003327:Coronary Disease; D004176:Dipyridamole; D004452:Echocardiography; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D005080:Exercise Test; D005260:Female; D006801:Humans; D006973:Hypertension; D017379:Hypertrophy, Left Ventricular; D008297:Male; D0088... | The Canadian journal of cardiology | 2,001 | D004176:Dipyridamole | |
Noninvasive assessment and monitoring of the pulmonary circulation. | In pulmonary vascular disease, changes in the pulmonary vascular bed will lead to altered pulmonary haemodynamics. This review describes the application of several physiological principles to measure these changes noninvasively by means of novel techniques. Flow characteristics of blood through the pulmonary vascular b... | 10.1183/09031936.05.00122104 | 15,802,353 | D003935:Diagnostic Techniques, Cardiovascular; D006801:Humans; D008279:Magnetic Resonance Imaging; D011652:Pulmonary Circulation; D012039:Regional Blood Flow; D014057:Tomography, X-Ray Computed | The European respiratory journal | 2,005 | |
The Rockford School of Medicine undergraduate quality assurance program. | An undergraduate program of ambulatory care quality assurance has been operational at the Rockford School of Medicine for three years. The original intent of the program was to increase the acceptance of quality assurance activities among student physicians, inculcating in them the importance of peer review at an early... | 10.1097/00001888-197605000-00003 | 1,263,227 | D000553:Ambulatory Care; D001291:Attitude of Health Personnel; D002641:Chicago; D003479:Curriculum; D004504:Education, Medical, Undergraduate; D005069:Evaluation Studies as Topic; D008485:Medical Audit; D008499:Medical Records; D010380:Peer Review | Journal of medical education | 1,976 | |
Correlation between effective peritoneal blood flow, blood pressure, and peritoneal transfer rates. | The aim of the studies was an evaluation of the correlation between effective peritoneal blood flow (EPBF), blood pressure, and peritoneal transfer during intermittent peritoneal dialysis (IPD). In 20 IPD patients it was shown that EPBF does not depend on either systolic or diastolic blood pressure. Differences in EPBF... | 8,865,865 | D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002199:Capillary Permeability; D003971:Diastole; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D010537:Peritoneum; D012039:Regional Blood Flow; D013599:Systole | Advances in peritoneal dialysis. Conference on Peritoneal Dialysis | 1,996 | ||
Optical Absorption Enhancement in CdTe Thin Films by Microstructuration of the Silicon Substrate. | In this work, the reflectance, optical absorption, and band gap have been determined for CdTe thin films grown on planar and microstructured substrates. The treated surface was prepared by laser ablation of a silicon wafer, forming holes in a periodic arrangement. Thin films were grown by pulsed laser ablation on silic... | 10.3390/ma10060607 | 28,772,967 | Materials (Basel, Switzerland) | 2,017 | ||
Optimization of lung function before pulmonary resection: pulmonologists' perspectives. | Many risk factors for morbidity and mortality with lung resection have been identified. Factors such as age, gender, and cancer stage cannot be altered, but lung function can be optimized by treating COPD or asthma with bronchodilators, corticosteroids, or antibiotics (when indicated) and by inspiratory muscle training... | 10.1016/S1547-4127(04)00018-0 | 15,382,761 | D006801:Humans; D008168:Lung; D008175:Lung Neoplasms; D018579:Patient Selection; D011013:Pneumonectomy; D011183:Postoperative Complications; D011300:Preoperative Care; D029424:Pulmonary Disease, Chronic Obstructive; D012129:Respiratory Function Tests; D012307:Risk Factors | Thoracic surgery clinics | 2,004 | |
Co-existence of heparin-induced thrombocytopenia and thrombotic thrombocytopenic purpura in a postoperative cardiac surgery patient. | Up to 50% of patients undergoing coronary artery bypass surgery will develop antibodies against the heparin-platelet factor 4 complex, and a small percentage of those will go on to develop heparin-induced thrombocytopenia. Thrombotic thrombocytopenic purpura has also been reported post-coronary artery bypass surgery. I... | 10.1002/ajh.20436 | 16,315,265 | D000925:Anticoagulants; D001026:Coronary Artery Bypass; D006493:Heparin; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D011183:Postoperative Complications; D011697:Purpura, Thrombotic Thrombocytopenic; D013921:Thrombocytopenia | American journal of hematology | 2,005 | D000925:Anticoagulants; D006493:Heparin |
[Development and reliability study of the adolescent inhalant use severity scale]. | OBJECTIVE
To develop a scale in order to investigate the severity of inhalant use in adolescents and to conduct reliability and validity studies of this scale.
METHOD
A questionnaire was developed by conducting interviews with two groups: professionals working with adolescent inhalant users and inhalant-using adolesc... | 16,362,845 | D000280:Administration, Inhalation; D000293:Adolescent; D005260:Female; D006801:Humans; D008297:Male; D010147:Pain Measurement; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D019966:Substance-Related Disorders; D011795:Surveys and Questionnaires | Turk psikiyatri dergisi = Turkish journal of psychiatry | 2,005 | ||
Spin-label studies on the aqueous regions of phospholipid multilayers. | Water-soluble spin labels were used to study dimyristoyllecithin (DML) phospholipid multilayers. Previous studies report that there is a "bound" water region associated with dimyristoyllecithin containing about 10 molecules of water per phospholipid, a "trapped" water region located between the lamellae containing appr... | 10.1021/bi00623a013 | 189,808 | D001665:Binding Sites; D004578:Electron Spin Resonance Spectroscopy; D008567:Membranes, Artificial; D008954:Models, Biological; D008968:Molecular Conformation; D010713:Phosphatidylcholines; D013113:Spin Labels | Biochemistry | 1,977 | D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D013113:Spin Labels |
An evaluation of bone scans as screening procedures for occult metastases in primary breast cancer. | Preoperative bone scans were obtained in 104 patients with operable breast cancer. Areas of increased radioactivity detected by the bone scan were correlated with appropriate radiographs. One of 64 patients (1.5%) with clinical Stage I and Stage II breast cancer had a metastatic lesion detected by the preoperative bone... | 10.1097/00000658-197709000-00014 | 889,378 | D000328:Adult; D000368:Aged; D001859:Bone Neoplasms; D001842:Bone and Bones; D001943:Breast Neoplasms; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008408:Mastectomy; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011859:Radiography; D011868:Radioiso... | Annals of surgery | 1,977 | D011868:Radioisotopes |
[Fermentative mechanisms of the psychrophilicity of Yersinia tuberculosis]. | The specific activity of urease, nitrogenase, hialuronidase and neuraminidase in Y. pseudotuberculosis grown in different culture media and at different temperature has been studied. These enzymes have been found capable of functioning at both relatively low (2-8 degrees C) and high (37 degrees C) temperatures. The the... | 6,369,842 | D002455:Cell Division; D003080:Cold Temperature; D003470:Culture Media; D005285:Fermentation; D007527:Isoenzymes; D011514:Proteus vulgaris; D013696:Temperature; D015007:Yersinia; D015008:Yersinia enterocolitica | Zhurnal mikrobiologii, epidemiologii i immunobiologii | 1,984 | D003470:Culture Media; D007527:Isoenzymes | |
Widowhood and divorce in relation to overall survival among middle-aged Norwegian women with cancer. | The aim of the study was to examine the relations between widowhood and divorce and overall survival among women with cancer. All Norwegian women born between 1935 and 1954, and diagnosed with cancer between 1966 and 1990, were followed up until 1991. In all, 14,231 cases were followed up for a median length of approxi... | 10.1038/bjc.1995.261 | 7,779,736 | D001943:Breast Neoplasms; D015179:Colorectal Neoplasms; D004243:Divorce; D016889:Endometrial Neoplasms; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms; D008393:Marriage; D008545:Melanoma; D008875:Middle Aged; D009369:Neoplasms; D009664:Norway; D010051:Ovarian Neoplasms; D012042:Regist... | British journal of cancer | 1,995 | |
Stam2 expression pattern during embryo development. | STAM2 is a tyrosine-phosphorylated protein suggested to be involved in cargo selection during endocytic pathway, regulation of exocytosis and intracellular signaling. Gene trap method was used to create via insertional mutagenesis a mutant mouse line with integration of promoterless βgeo (lacZ-neomycin phosphotransfera... | 10.1016/j.gep.2011.11.005 | 22,143,071 | D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D033481:Chromosomes, Mammalian; D004622:Embryo, Mammalian; D047108:Embryonic Development; D056827:Endosomal Sorting Complexes Required for Transport; D018507:Gene Expression Regulation, Developmental; D017930:Genes, Reporter; D005822:Genetic Vectors; D00672... | Gene expression patterns : GEP | 2,012 | D048868:Adaptor Proteins, Signal Transducing; D056827:Endosomal Sorting Complexes Required for Transport; D010750:Phosphoproteins; C491646:Stam2 protein, mouse; D001616:beta-Galactosidase |
Multifunctional branched gold-carbon nanotube hybrid for cell imaging and drug delivery. | Branched gold nanoparticles were grown on oxidized multiwalled carbon nanotubes by one-step reduction of gold chloride in water. The carbon nanotube/gold hybrids were used for the delivery of the anticancer drug doxorubicin hydrochloride into A549 lung cancer cell line. Doxorubicin (Dox) can be adsorbed in high quantit... | 10.1021/la303298u | 23,083,447 | D000970:Antineoplastic Agents; D004317:Doxorubicin; D016503:Drug Delivery Systems; D006046:Gold; D006801:Humans; D008175:Lung Neoplasms; D053768:Metal Nanoparticles; D037742:Nanotubes, Carbon; D010316:Particle Size; D013499:Surface Properties; D014407:Tumor Cells, Cultured | Langmuir : the ACS journal of surfaces and colloids | 2,012 | D000970:Antineoplastic Agents; D037742:Nanotubes, Carbon; D006046:Gold; D004317:Doxorubicin |
Multiple exposure and effects assessment of heavy metals in the population near mining area in South China. | The objective of this study was to investigate the levels of Cd, Pb, Cu and Zn in the environment and several important food sources grown and consumed in the vicinity of Dabaoshan mine in Southern China, and evaluate potential health risks among local residents. The Cd, Pb, Cu and Zn concentrations of arable soils and... | 10.1371/journal.pone.0094484 | 24,728,502 | D002681:China; D004032:Diet; D004784:Environmental Monitoring; D004785:Environmental Pollutants; D020387:Food Chain; D005506:Food Contamination; D005843:Geography; D014943:Global Health; D006197:Hair; D006801:Humans; D019216:Metals, Heavy; D008906:Mining; D014874:Water Pollutants, Chemical; D060986:Water Wells | PloS one | 2,014 | D004785:Environmental Pollutants; D019216:Metals, Heavy; D014874:Water Pollutants, Chemical |
Prevalence and determinants of unintended pregnancy in sub-Saharan Africa: A multi-country analysis of demographic and health surveys. | INTRODUCTION
Approximately 14 million unintended pregnancies are recorded annually in sub-Saharan Africa (SSA). We sought to investigate the prevalence and determinants of unintended pregnancies among women in sub-Saharan Africa.
MATERIALS AND METHODS
The study pooled data from current Demographic and Health Surveys ... | 10.1371/journal.pone.0220970 | 31,398,240 | D000293:Adolescent; D000328:Adult; D017954:Africa South of the Sahara; D005260:Female; D006306:Health Surveys; D006801:Humans; D038622:Internationality; D016015:Logistic Models; D008875:Middle Aged; D011247:Pregnancy; D049168:Pregnancy, Unplanned; D015995:Prevalence; D055815:Young Adult | PloS one | 2,019 | |
[Erythrocyte aggregation indicator, hematocrit and plasma viscosity in patients with a vascular form of vibration disease]. | In 82 men suffering from the vascular form of the vibration disease divided by its advancement into two groups: group I of 42 persons (aged, on average, 40 +/- 7.5) at an early stage of the disease and group II consisting of 40 persons (aged, on average, 49.7 +/- 5.6) at an advanced stage of the disease--haematocrit, p... | 4,068,986 | D000328:Adult; D001799:Blood Sedimentation; D001809:Blood Viscosity; D004903:Erythrocyte Aggregation; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases; D011928:Raynaud Disease; D013997:Time Factors; D014732:Vibration | Medycyna pracy | 1,985 | ||
Nephrogenic adenoma of the ureter in a teenager with history of leukemia. | Nephrogenic adenomas represent a suspected metaplastic response of the uroepithelium to chronic inflammation and are typically associated with recurrent urinary tract infections, stones, prior radiation therapy and other irritative factors, more commonly seen in adults. Nephrogenic adenoma (also known as nephrogenic me... | 10.1016/j.radcr.2021.03.002 | 33,897,934 | Radiology case reports | 2,021 | ||
Estimated effectiveness of school closure and voluntary event cancellation as COVID-19 countermeasures in Japan. | BACKGROUND
As countermeasures against the COVID-19 outbreak, sports and entertainment events were canceled (VEC) in Japan for two weeks from 26 February through 13 March. Moreover, most schools were closed (SC).
OBJECTIVE
For this study, we estimated the basic reproduction number (R0) and SC and VEC effects.
METHOD... | 10.1016/j.jiac.2020.08.012 | 32,896,479 | D000328:Adult; D000368:Aged; D050936:Basic Reproduction Number; D000073640:Betacoronavirus; D000086382:COVID-19; D002648:Child; D018352:Coronavirus Infections; D004196:Disease Outbreaks; D006801:Humans; D007564:Japan; D015233:Models, Statistical; D058873:Pandemics; D011024:Pneumonia, Viral; D000086402:SARS-CoV-2; D0125... | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy | 2,021 | |
Changes in thyroid-stimulating immunoglobulins during antithyroid therapy. | Thyroid-stimulating immunoglobulin (TSI) activity was measured by radioreceptor assay in sera from patients with Graves' disease, Hashimoto's thyroiditis, and thyroid cancer. In untreated Graves' disease (47 cases), TSI index was significantly lower [76.7 +/- 1.4 (SE)] than the average of a normal control group (30 cas... | 10.1210/jcem-48-4-572 | 581,875 | D000328:Adult; D000368:Aged; D000818:Animals; D001681:Biological Assay; D002417:Cattle; D002462:Cell Membrane; D005260:Female; D006111:Graves Disease; D006801:Humans; D007074:Immunoglobulin G; D008135:Long-Acting Thyroid Stimulator; D008297:Male; D008875:Middle Aged; D013961:Thyroid Gland; D013964:Thyroid Neoplasms; D0... | The Journal of clinical endocrinology and metabolism | 1,979 | D007074:Immunoglobulin G; D013972:Thyrotropin; D008135:Long-Acting Thyroid Stimulator |
Scoliosis management in Duchenne muscular dystrophy: prospective study of modified Jewett hyperextension brace. | The management of scoliosis in Duchenne muscular dystrophy is not standardized. Some centers offer no treatment, some provide customized body jackets or wheelchair inserts, and others recommend early surgical spinal fusion. Spinal orthoses are frequently prescribed at significant cost and inconvenience to the patient, ... | 3,579,538 | D000293:Adolescent; D001915:Braces; D002648:Child; D005069:Evaluation Studies as Topic; D006801:Humans; D009136:Muscular Dystrophies; D011446:Prospective Studies; D012121:Respiration, Artificial; D012600:Scoliosis; D013131:Spine; D014797:Vital Capacity | Archives of physical medicine and rehabilitation | 1,987 | ||
Evaluating the Authenticity of the Raw-Milk Cheese Fontina (PDO) with Respect to Similar Cheeses. | The implementation of quality assurance schemes for the assessment of PDO food authenticity is an issue involving manufacturers, traders, retailers and consumers. In this respect, reliable analytical methods are needed to integrate paper-trailing information. The feasibility of distinguishing the Italian Fontina PDO ch... | 10.3390/foods10020350 | 33,562,236 | Foods (Basel, Switzerland) | 2,021 | ||
Increased risk of breast cancer after low-dose irradiation. | A significant increase in the risk of breast cancer has been found for the most recent 5-year period of a long-term follow-up study of children subjected to scalp irradiation, in whom a carcinogenic effect was previously only apparent in the head and neck. This increased risk was found among women aged 5 to 9 years at ... | 10.1016/s0140-6736(89)92140-5 | 2,564,456 | D000293:Adolescent; D000367:Age Factors; D001943:Breast Neoplasms; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009381:Neoplasms, Radiation-Induced; D011829:Radiation Dosage; D012307:Risk Factors; D014006:Tinea... | Lancet (London, England) | 1,989 | |
Effects of early undernutrition on kinetic parameters of brain acetylcholinesterase from adult rats. | The effects of undernutrition during early life on acetylcholinesterase (AChE) specific activity of cerebellum, hippocampus, hypothalamus and striatum were examined in rehabilitated adults rats. Undernourished rats were raised by dams maintained on a restricted food scheme from pup birth to pup weaning (day 31). The of... | 8,249,659 | D000110:Acetylcholinesterase; D000818:Animals; D001921:Brain; D005260:Female; D007700:Kinetics; D008297:Male; D009748:Nutrition Disorders; D051381:Rats; D017208:Rats, Wistar | Acta neurobiologiae experimentalis | 1,993 | D000110:Acetylcholinesterase | |
Cladribine. | Cladribine is a novel drug that selectively depletes lymphocytes and may be able to destroy the activated immunocytes that damage the central nervous system in multiple sclerosis. Our initial controlled studies have shown a beneficial, although temporary, dose-related effect of cladribine on the course of chronic progr... | 10.2165/00063030-199707050-00006 | 18,031,102 | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy | 1,997 | ||
Laminar boundaries persist in the hippocampal dentate molecular layer of the mutant Shaking Rat Kawasaki despite aberrant granule cell migration. | The present report provides the first detailed description of the hippocampus in the Shaking Rat Kawasaki (SRK) mutant by using a panel of antibody markers to delineate its laminar organization. The mutant was characterised at postnatal day 21 by severe malformations of both neuronal position and orientation, the most ... | 10.1002/(sici)1096-9861(19990621)409:1<57::aid-cne5>3.0.co;2-# | 10,363,711 | D000818:Animals; D001369:Axons; D064032:Calbindin 2; D002465:Cell Movement; D018891:Dentate Gyrus; D006624:Hippocampus; D008032:Limbic System; D051379:Mice; D008818:Mice, Neurologic Mutants; D009154:Mutation; D009434:Neural Pathways; D009474:Neurons; D017966:Pyramidal Cells; D051381:Rats; D017208:Rats, Wistar; D064030:... | The Journal of comparative neurology | 1,999 | C576511:Calb2 protein, mouse; C576512:Calb2 protein, rat; D064032:Calbindin 2; D064030:S100 Calcium Binding Protein G |
Artificial Intelligence in Cardiac Imaging With Statistical Atlases of Cardiac Anatomy. | In many cardiovascular pathologies, the shape and motion of the heart provide important clues to understanding the mechanisms of the disease and how it progresses over time. With the advent of large-scale cardiac data, statistical modeling of cardiac anatomy has become a powerful tool to provide automated, precise quan... | 10.3389/fcvm.2020.00102 | 32,695,795 | Frontiers in cardiovascular medicine | 2,020 | ||
Improved plasma cholesterol levels in men after a nutrition education program at the worksite. | Eighty management-level male employees participated in a company-sponsored comprehensive physical that included determination of plasma total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglyceride levels and percentage of body fat. After the lipid screening, each employ... | 10.1016/0002-8223(93)91672-d | 8,389,779 | D000273:Adipose Tissue; D000328:Adult; D001835:Body Weight; D002784:Cholesterol; D002791:Cholesterol, Dietary; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004032:Diet; D015930:Diet Records; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber; D002149:Energy Intake; D005500:Follow-Up Stud... | Journal of the American Dietetic Association | 1,993 | D002791:Cholesterol, Dietary; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber; D014280:Triglycerides; D002784:Cholesterol |
An optical aptasensor for aflatoxin M1 detection based on target-induced protection of gold nanoparticles against salt-induced aggregation and silica nanoparticles. | Not only intoxications of aflatoxins are significant risk for human beings, but also; the contamination with these toxins affect the economy. Therefore, developing a rapid, precise and inexpensive determination method is vitally important. Here, a colorimetric aptasensor is introduced for the detection of aflatoxin M1 ... | 10.1016/j.saa.2020.119062 | 33,080,511 | D016607:Aflatoxin M1; D052157:Aptamers, Nucleotide; D015374:Biosensing Techniques; D003124:Colorimetry; D005506:Food Contamination; D006046:Gold; D053768:Metal Nanoparticles; D012822:Silicon Dioxide; D012965:Sodium Chloride | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy | 2,021 | D052157:Aptamers, Nucleotide; D012965:Sodium Chloride; D016607:Aflatoxin M1; D006046:Gold; D012822:Silicon Dioxide |
Serum proteomic-based analysis of pancreatic carcinoma for the identification of potential cancer biomarkers. | To identify new biomarkers that improve the early diagnosis and lead to possible therapeutic targets in pancreatic carcinoma, we performed a proteomic approach to compare serum protein expression patterns of pancreatic carcinoma patients with that of gastric cancer patients, other pancreatic disease patients, and healt... | 10.1016/j.bbapap.2007.04.001 | 17,507,299 | D014408:Biomarkers, Tumor; D001798:Blood Proteins; D015153:Blotting, Western; D056749:Cyclin I; D016213:Cyclins; D015180:Electrophoresis, Gel, Two-Dimensional; D020730:Guanine Nucleotide Dissociation Inhibitors; D006262:Health; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D010190:Pancreatic Neopla... | Biochimica et biophysica acta | 2,007 | D014408:Biomarkers, Tumor; D001798:Blood Proteins; C534756:CCNI protein, human; D056749:Cyclin I; D016213:Cyclins; D020730:Guanine Nucleotide Dissociation Inhibitors |
[Methodological issues in the measurement of alcohol consumption: the importance of drinking patterns]. | Measurement of alcohol consumption is essential for proper investigation of its effects on health. However, its estimation is extremely complex, because of the diversity of forms of alcohol consumption and their highly heterogeneous classification. Moreover, each form may have different effects on health; therefore, no... | 25,090,403 | D000428:Alcohol Drinking; D063425:Binge Drinking; D004812:Epidemiologic Methods; D006306:Health Surveys; D006801:Humans; D013030:Spain | Revista espanola de salud publica | 2,014 | ||
Effect of temperature on DNA secondary structure in the absence and presence of 0.5 M tetramethylammonium chloride. | Changes in the average secondary structures of three different linear DNAs over the premelting region from 5 to 60 degrees C were investigated by measuring their CD spectra and also their torsion elastic constants (<alpha>) by time-resolved fluorescence polarization anisotropy. For one of these DNAs, the Haell fragment... | 10.1002/(SICI)1097-0282(199806)45:7<503::AID-BIP4>3.0.CO;2-S | 9,577,231 | D002942:Circular Dichroism; D004247:DNA; D015252:Deoxyribonucleases, Type II Site-Specific; D004058:Diffusion; D005454:Fluorescence Polarization; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D009838:Oligodeoxyribonucleotides; D010957:Plasmids; D000644:Quaternary Ammonium Compounds; D012542:Scat... | Biopolymers | 1,998 | D009838:Oligodeoxyribonucleotides; D000644:Quaternary Ammonium Compounds; D004247:DNA; C031851:endodeoxyribonuclease HaeII; D015252:Deoxyribonucleases, Type II Site-Specific; C027917:tetramethylammonium |
Hemifield relative motion bias in adults monocularly enucleated at an early age. | A psychophysical study of relative motion discrimination for six subjects monocularly enucleated within 24 months of birth showed no significant difference in their thresholds for detecting relative velocity when compared with age matched control subjects. The study however highlighted a bias for the control group, age... | 10.1016/0042-6989(94)90072-8 | 7,863,621 | D000328:Adult; D004192:Discrimination, Psychological; D015353:Eye Enucleation; D006801:Humans; D008433:Mathematics; D009039:Motion Perception; D010364:Pattern Recognition, Visual; D010468:Perceptual Disorders; D011594:Psychometrics; D012684:Sensory Thresholds; D015349:Vision, Monocular | Vision research | 1,994 | |
Control of heterogeneous Fe(III) (hydr)oxide nucleation and growth by interfacial energies and local saturations. | To predict the fate of aqueous pollutants, a better understanding of heterogeneous Fe(III) (hydr)oxide nucleation and growth on abundant mineral surfaces is needed. In this study, we measured in situ heterogeneous Fe(III) (hydr)oxide nucleation and growth on quartz, muscovite, and corundum (Al2O3) in 10(-4) M Fe(III) s... | 10.1021/es401160g | 23,875,694 | D011232:Chemical Precipitation; D005290:Ferric Compounds; D053768:Metal Nanoparticles; D013500:Surface Tension; D014961:X-Ray Diffraction | Environmental science & technology | 2,013 | D005290:Ferric Compounds; C021024:ferric hydroxide |
Matrix metalloproteinases and their inhibitors as biomarkers for metal toxicity in vitro. | Exposure to nickel and chromium, and their compounds, has been associated with adverse health effects. These metals are two human carcinogens whose pathogenesis involves active extracellular matrix degradation and remodelling. In this work we have compared the effects of in vitro exposure to nickel and chromium of a ke... | 10.1016/j.tiv.2006.02.004 | 16,581,223 | D015415:Biomarkers; D002455:Cell Division; D002460:Cell Line; D002470:Cell Survival; D004305:Dose-Response Relationship, Drug; D005434:Flow Cytometry; D016193:G1 Phase; D015870:Gene Expression; D006801:Humans; D015603:Keratinocytes; D020781:Matrix Metalloproteinase 1; D020778:Matrix Metalloproteinase 2; D020782:Matrix ... | Toxicology in vitro : an international journal published in association with BIBRA | 2,006 | D015415:Biomarkers; D019216:Metals, Heavy; D012333:RNA, Messenger; D019715:Tissue Inhibitor of Metalloproteinase-1; D019714:Tissue Inhibitor of Metalloproteinases; D019716:Tissue Inhibitor of Metalloproteinase-2; C029938:nickel sulfate; D009532:Nickel; D020782:Matrix Metalloproteinases; D020778:Matrix Metalloproteinase... |
Economics of robotic surgery: does it make sense and for whom? | The authors performed a literature review to identify cost-effectiveness research as it pertains to robotic surgery. There is increased utilization of robotic surgery in urology with limited comparative effectiveness research demonstrating superiority over conventional, less costly treatment options. Further research i... | 25,306,170 | D003362:Cost-Benefit Analysis; D006801:Humans; D010535:Laparoscopy; D011468:Prostatectomy; D065287:Robotic Surgical Procedures | The Urologic clinics of North America | 2,014 | ||
Elevated blood pressure in primary care varies in relation to circadian and seasonal changes. | Blood pressure (BP) is known to vary by time of day and day of year. Studies differ substantially on the magnitude of the effect and there is doubt whether variation is clinically meaningful. We used more than 2 million BP measurements obtained between 1996 and 2004 from Geisinger Clinic primary care patients. General ... | 10.1038/jhh.2008.44 | 18,528,410 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D001795:Blood Pressure Determination; D002940:Circadian Rhythm; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension; D008297:Male; D008875:Middle Aged; D010414:Pennsylvania; D015995:Prevalence... | Journal of human hypertension | 2,008 | |
Prolactin and natural killer cells: evaluating the neuroendocrine-immune axis in women with primary infertility and recurrent spontaneous abortion. | PROBLEM
An association between serum prolactin (PRL) and peripheral blood natural killer (NK) cells has been described in healthy women. We explored for the first time the PRL response to the thyrotrophin-releasing hormone (TRH) test and the association between PRL and NK cells in women with reproductive failure.
MET... | 10.1111/aji.12335 | 25,345,488 | D000026:Abortion, Habitual; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D007246:Infertility; D007694:Killer Cells, Natural; D009452:Neuroendocrinology; D011247:Pregnancy; D011388:Prolactin; D013973:Thyrotropin-Releasing Hormone | American journal of reproductive immunology (New York, N.Y. : 1989) | 2,015 | D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin |
Joining characteristics of titanium-based orthodontic wires connected by laser and electrical welding methods. | This study investigated the possibility of electrical and laser welding to connect titanium-based alloy (beta-titanium and nickel-titanium) wires and stainless-steel or cobalt-chromium alloy wires for fabrication of combination arch-wires. Four kinds of straight orthodontic rectangular wires (0.017 × 0.025 inch) were u... | 10.1007/s10856-015-5391-9 | 25,595,723 | D000497:Alloys; D002857:Chromium; D003035:Cobalt; D006801:Humans; D007834:Lasers; D008422:Materials Testing; D009532:Nickel; D009969:Orthodontic Wires; D009970:Orthodontics; D015203:Reproducibility of Results; D013193:Stainless Steel; D013314:Stress, Mechanical; D013718:Tensile Strength; D014025:Titanium; D014070:Tooth | Journal of materials science. Materials in medicine | 2,015 | D000497:Alloys; D002857:Chromium; D013193:Stainless Steel; D003035:Cobalt; D009532:Nickel; D014025:Titanium |
Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 αC helix. | The mechanisms by which JAK2 is activated by the prevalent pseudokinase (JH2) V617F mutation in blood cancers remain elusive. Via structure-guided mutagenesis and transcriptional and functional assays, we identify a community of residues from the JH2 helix αC, SH2-JH2 linker and JH1 kinase domain that mediate V617F-ind... | 10.1042/BCJ20160085 | 27,029,346 | D015153:Blotting, Western; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D016207:Cytokines; D005434:Flow Cytometry; D006801:Humans; D053614:Janus Kinase 2; D009154:Mutation; D010766:Phosphorylation; D000072417:Protein Domains | The Biochemical journal | 2,016 | D016207:Cytokines; C507924:JAK2 protein, human; D053614:Janus Kinase 2 |
Structural diversity of alkali-metal (Li, Na, K) alkyl zincates containing bidentate aminopyrrolyl ligands: from molecular complexes to coordination polymers. | The exploration of co-complexation reactions between alkai-metal reagents and ZnEt2 with bidentate aminopyrrolyl ligands afforded a series of alkali-metal (Li, Na, K) alkyl zincates with a variety of intriguing structures, ranging from molecular complexes to more coordination polymers. All aforementioned complexes have... | 10.1039/c7dt00052a | 28,186,519 | Dalton transactions (Cambridge, England : 2003) | 2,017 | ||
Physical activity for people with lung cancer. | BACKGROUND
International guidelines recommend exercise for all people with cancer. Effective supportive care interventions are required for people diagnosed with lung cancer to reduce morbidity associated with the disease process, frequently occurring comorbidities and treatment-related side effects.
OBJECTIVE
This a... | 10.31128/AJGP-09-19-5060 | 32,233,342 | D015444:Exercise; D006801:Humans; D008175:Lung Neoplasms; D053580:Muscle Strength; D010166:Palliative Care; D011788:Quality of Life | Australian journal of general practice | 2,020 | |
Catalytic enantioselective synthesis of benzocyclobutenols and cyclobutanols via a sequential reduction/C-H functionalization. | We report here a sequential enantioselective reduction/C-H functionalization to install contiguous stereogenic carbon centers of benzocyclobutenols and cyclobutanols. This strategy features a practical enantioselective reduction of a ketone and a diastereospecific iridium-catalyzed C-H silylation. Further transformatio... | 10.1039/d1sc02119b | 34,447,553 | Chemical science | 2,021 | ||
[The correlation between toe- and ankle pressure, clinical symptoms and angiography in patients with leg ischemia]. | OBJECTIVE
The severity of leg ischemia is usually evaluated by measuring ankle pressure. This is a simple measurement but can be misleading in patients with severe sclerosis in ankle arteries in which case toe pressure is believed to be more reliable. The purpose of this study was to compare toe pressure with ankle pre... | 16,219,974 | D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D000842:Ankle; D001157:Arterial Occlusive Diseases; D001794:Blood Pressure; D001795:Blood Pressure Determination; D005260:Female; D006801:Humans; D007511:Ischemia; D035002:Lower Extremity; D008297:Male; D008875:Middle Aged; D014034:Toes | Laeknabladid | 2,005 | ||
Drug Target Validation of the Protein Kinase AEK1, Essential for Proliferation, Host Cell Invasion, and Intracellular Replication of the Human Pathogen Trypanosoma cruzi. | Protein phosphorylation is involved in several key biological roles in the complex life cycle of Trypanosoma cruzi, the etiological agent of Chagas disease, and protein kinases are potential drug targets. Here, we report that the AGC essential kinase 1 (TcAEK1) exhibits a cytosolic localization and a higher level of ex... | 10.1128/Spectrum.00738-21 | 34,585,973 | D049109:Cell Proliferation; D014355:Chagas Disease; D048749:Cytokinesis; D003600:Cytosol; D000072669:Gene Editing; D055785:Gene Knockdown Techniques; D006801:Humans; D008018:Life Cycle Stages; D011494:Protein Kinases; D014349:Trypanosoma cruzi | Microbiology spectrum | 2,021 | D011494:Protein Kinases |
Adjuvant FOLFOX+Nab-Paclitaxel (FOLFOX-A) for Pancreatic Cancer: A Brown University Oncology Research Group Phase II Study (BrUOG295). | OBJECTIVES
Multiple clinical trials have established a role for adjuvant chemotherapy for patients with pancreatic ductal adenocarcinoma. Adjuvant FOLFIRINOX increases survival as compared with gemcitabine but with increased toxicity. FOLFOX+nab-paclitaxel (FOLFOX-A) was developed by the Brown University Oncology Resea... | 10.1097/COC.0000000000000762 | 32,976,178 | D000328:Adult; D000368:Aged; D000418:Albumins; D000971:Antineoplastic Combined Chemotherapy Protocols; D021441:Carcinoma, Pancreatic Ductal; D017024:Chemotherapy, Adjuvant; D005260:Female; D005472:Fluorouracil; D006801:Humans; D002955:Leucovorin; D008297:Male; D020714:Maximum Tolerated Dose; D008875:Middle Aged; D00994... | American journal of clinical oncology | 2,020 | C520255:130-nm albumin-bound paclitaxel; D000418:Albumins; D009944:Organoplatinum Compounds; D017239:Paclitaxel; D002955:Leucovorin; D005472:Fluorouracil |
Low levels of unsaturated transferrin as a predictor of survival in pneumococcal pneumonia. | A study was conducted to evaluate factors which might influence the prognosis of persons with pneumonia owing to Streptococcus pneumoniae. Serum iron, total iron binding capacity and unbound iron binding capacity (UIBC), were evaluated in 35 such patients. Of the 10 patients with UIBC levels less than 130 micrograms pe... | 2,327,729 | D006801:Humans; D007501:Iron; D011018:Pneumonia, Pneumococcal; D011379:Prognosis; D014168:Transferrin | Annals of clinical and laboratory science | 1,990 | D014168:Transferrin; D007501:Iron | |
Protective Effect of a Bispecific Fc-Fusion Protein on the Barrier of Human Retinal Pigment Epithelial Cells. | INTRODUCTION
The aim of the study was to evaluate the protective effects of IBI302, a bispecific Fc-fusion protein that theoretically can bind vascular endothelial growth factor (VEGF), complement C3b, and C4b in the barrier of the cultured human retinal pigment epithelial (hRPE) cells.
METHODS
Primary hRPE cells wer... | 10.1159/000515053 | 33,550,303 | D002478:Cells, Cultured; D004847:Epithelial Cells; D006801:Humans; D012168:Retinal Pigments; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors | Ophthalmic research | 2,021 | D012168:Retinal Pigments; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors |
Ferrara beta 0 thalassaemia caused by the beta 39 nonsense mutation. | Ferrara type of beta 0 thalassaemia has two unusual features: first, normal beta-globin chain synthesis is inducible either in cell-free systems prepared from patients' reticulocytes by adding supernatant factors from non-thalassaemic reticulocyte lysates or in heterologous cell-free translation of thalassaemic mRNA; s... | 10.1038/307076a0 | 6,690,987 | D005786:Gene Expression Regulation; D005914:Globins; D006801:Humans; D009154:Mutation; D013489:Suppression, Genetic; D013789:Thalassemia | Nature | 1,984 | D005914:Globins |
Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease. | CONTEXT
Nonalcoholic fatty liver disease is associated with risk factors for cardiovascular disease, particularly increased plasma triglyceride (TG) concentrations and insulin resistance. Fenofibrate and extended release nicotinic acid (Niaspan) are used to treat hypertriglyceridemia and can affect fatty acid oxidation... | 10.1210/jc.2009-2622 | 20,371,660 | D000328:Adult; D001055:Apolipoproteins B; D001786:Blood Glucose; D001823:Body Composition; D004311:Double-Blind Method; D005230:Fatty Acids, Nonesterified; D005234:Fatty Liver; D005260:Female; D011345:Fenofibrate; D015309:Glucose Clamp Technique; D006801:Humans; D000960:Hypolipidemic Agents; D007328:Insulin; D007333:In... | The Journal of clinical endocrinology and metabolism | 2,010 | D001055:Apolipoproteins B; D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D000960:Hypolipidemic Agents; D007328:Insulin; D008079:Lipoproteins, VLDL; D014280:Triglycerides; D009525:Niacin; D011345:Fenofibrate |
The traditional ethnic herb Tadehagi triquetrum from China: a review of its phytochemistry and pharmacological activities. | CONTEXT
Tadehagi triquetrum (Linn.) Ohashi (Fabaceae) (TT), is a traditional herbal medicine used especially in China's ethnic-minority communities, such as the Zhuang, Dai, Li and Wa aeras. As an ethnic medicine, it has long been used to treat various diseases.
OBJECTIVE
This review summarised the phytochemical and ... | 10.1080/13880209.2022.2052908 | 35,361,038 | D002681:China; D020834:Ethnopharmacology; D007887:Fabaceae; D008516:Medicine, Chinese Traditional; D008517:Phytotherapy | Pharmaceutical biology | 2,022 | |
Effects of Breakfast Omission on Resting, Exercise, and Postexercise Autonomic and Hemodynamic Profile in Men. | Purpose: The acute effects of fasting interventions on metabolic dynamics have been widely investigated. However, knowledge about the acute effect of overnight fasting on hemodynamic and cardiac autonomic modulation is limited, especially during and after exercise. Our objective was to investigate the effects of breakf... | 10.1080/02701367.2020.1825603 | 33,054,695 | D000328:Adult; D001341:Autonomic Nervous System; D001794:Blood Pressure; D062408:Breakfast; D015444:Exercise; D005080:Exercise Test; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D008297:Male; D012146:Rest; D055815:Young Adult | Research quarterly for exercise and sport | 2,022 | |
The Role of Electronic Patient-Reported Outcome Measures in Assessing Smoking Status and Cessation for Patients with Lung Cancer. | INTRODUCTION
Smoking cessation following lung cancer diagnosis is recommended to improve patient outcomes. Electronic Patient Reported Outcome Measures (ePROMs) may be useful for identifying and facilitating cessation support in patients that continue to smoke after a cancer diagnosis. The primary aim was to investigat... | 10.1007/s40487-022-00210-7 | 36,223,028 | Oncology and therapy | 2,022 | ||
Mediterranean and Amerindian MHC class II alleles are associated with multiple sclerosis in Mexicans. | OBJECTIVES
Human leukocyte antigen (HLA)-DRB1, DQA1, DQB1 allele typing was performed in Mexicans Mestizos with multiple sclerosis (MS) to define the HLA class II alleles associated with the disease in this population.
METHODS
Patients (n = 51) diagnosed according to the Poser criteria and a group of 173 unrelated he... | 10.1111/j.1600-0404.2005.00493.x | 16,218,914 | D000293:Adolescent; D000328:Adult; D000483:Alleles; D005006:Ethnicity; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; D059866:HLA-DQ beta-Chains; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; D000949:Histocom... | Acta neurologica Scandinavica | 2,005 | D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; D059866:HLA-DQ beta-Chains; C069050:HLA-DQA1 antigen; C069051:HLA-DQB1 antigen; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; D000949:Histocompatibility Antigens Class II |
Influence of linoleic acid on desaturation and uptake of deuterium-labeled palmitic and stearic acids in humans. | Objectives of this study were to investigate the desaturation of stearic acid (18:0) and palmitic acid (16:0), to determine if differences in their metabolism provide a reasonable explantation for differences in their effect on serum cholesterol levels, and to investigate the affect of linoleic acid on delta 9-desatura... | 10.1016/0005-2760(93)90068-k | 8,399,342 | D000328:Adult; D002914:Chylomicrons; D003903:Deuterium; D004042:Dietary Fats, Unsaturated; D044943:Fatty Acid Desaturases; D005231:Fatty Acids, Unsaturated; D006801:Humans; D006937:Hypercholesterolemia; D007408:Intestinal Absorption; D019787:Linoleic Acid; D008041:Linoleic Acids; D008055:Lipids; D008297:Male; D019301:O... | Biochimica et biophysica acta | 1,993 | D002914:Chylomicrons; D004042:Dietary Fats, Unsaturated; D005231:Fatty Acids, Unsaturated; D008041:Linoleic Acids; D008055:Lipids; D009829:Oleic Acids; D010169:Palmitic Acids; D010713:Phosphatidylcholines; D013229:Stearic Acids; D014280:Triglycerides; D019301:Oleic Acid; D019308:Palmitic Acid; C031183:stearic acid; D01... |
Iteamine, the first alkaloid isolated from Itea virginica L. inflorescence. | Iteamine, o-aminobenzyl β-D-glucopyranoside, is the first alkaloid to be isolated from Itea virginica. Itea is the sole plant source of D-psicose, a rare sugar likely to be a major dietary supplement. The structure of iteamine was established by NMR and confirmed by total synthesis. Iteamine and its galacto-analog (whi... | 24,534,106 | D000470:Alkaloids; D000818:Animals; D004791:Enzyme Inhibitors; D005960:Glucosides; D056626:Inflorescence; D064028:Tracheophyta; D048809:alpha-N-Acetylgalactosaminidase | Phytochemistry | 2,014 | D000470:Alkaloids; D004791:Enzyme Inhibitors; D005960:Glucosides; C000592500:iteamine; D048809:alpha-N-Acetylgalactosaminidase | |
Opening the black box in nursing work and management practice: the role of ward managers. | AIM
This paper aims to identify and explore key obstacles preventing ward managers from effectively performing the human resource management (HRM) responsibilities required in their role.
BACKGROUND
In the context of increasing costs and the decentralisation of responsibility to ward level, the relevance of the ward ... | 10.1111/jonm.12115 | 23,859,179 | D001291:Attitude of Health Personnel; D003220:Conflict, Psychological; D006801:Humans; D007857:Leadership; D009718:Nurse Administrators; D024802:Nurse's Role; D019982:Organizational Case Studies; D036301:Qualitative Research; D013192:Staff Development | Journal of nursing management | 2,015 | |
Familial transmission of a body-related attentional bias - An eye-tracking study in a nonclinical sample of female adolescents and their mothers. | BACKGROUND
Previous research indicates that body image disturbance is transmitted from mother to daughter via modeling of maternal body-related behaviors and attitudes (indirect transmission) and via maternal body-related feedback (direct transmission). So far, the transmission of body-related attentional biases, which... | 10.1371/journal.pone.0188186 | 29,176,821 | D000293:Adolescent; D000070379:Attentional Bias; D001828:Body Image; D005133:Eye Movements; D005190:Family; D005246:Feedback; D005260:Female; D006801:Humans; D008962:Models, Theoretical; D009035:Mothers | PloS one | 2,017 | |
A helical structure with Z' = 10. | The structure of N''-cyano-N,N-diisopropylguanidine, a push-pull nitrile that includes the H(2)N-C=N-CN fragment, has been determined. Although the number of molecules in the asymmetric unit is exceptionally high (Z' = 10), there were no special crystallographic difficulties associated with data collection, structure s... | 10.1107/S0108768105004076 | 15,772,455 | Acta crystallographica. Section B, Structural science | 2,005 | ||
Polymer based advanced recipes for imidazoles: a review. | Imidazoles and their scaffold are an extraordinarily essential class of nitrogen bearing azole heterocyclic compounds. They have different place in wide area of organic synthesis, which can be utilized in a variety of applications in diverse fields including agriculture, medicine, polymer and various industries. Numero... | 10.55730/1300-0527.3357 | 37,720,618 | Turkish journal of chemistry | 2,022 | ||
Super suppressor action spectrum in Neurospora. | The action of super suppressors mapping at eight separate loci upon ten different nonsense mutants is examined. These suppressors can be subdivided into seven classes based upon their capacity to restore function to the test mutants. | 10.1007/BF00268551 | 136,592 | D002874:Chromosome Mapping; D005815:Genetic Code; D009154:Mutation; D009491:Neurospora; D009492:Neurospora crassa; D010443:Peptide Chain Termination, Translational; D010641:Phenotype; D013489:Suppression, Genetic | Molecular & general genetics : MGG | 1,976 | |
Cell trafficking of carbon nanotubes based on fluorescence detection. | Cell trafficking of carbon nanotubes (CNTs) is an area of scientific inquiry that has great implications in medicine, biosensing, and environmental science and engineering. The essence of this inquiry resides in the interaction of carbon nanostructures and cell membranes, regulated by the laws of molecular cell biology... | 10.1007/978-1-60761-579-8_12 | 20,422,387 | D002462:Cell Membrane; D020099:Coated Materials, Biocompatible; D031541:Fluorescence Resonance Energy Transfer; D006801:Humans; D008856:Microscopy, Fluorescence; D037742:Nanotubes, Carbon; D012680:Sensitivity and Specificity; D014018:Tissue Distribution; D014407:Tumor Cells, Cultured | Methods in molecular biology (Clifton, N.J.) | 2,010 | D020099:Coated Materials, Biocompatible; D037742:Nanotubes, Carbon |
Effect of chlorpromazine on Purkinje cell growth patterns. | The phenothiazine, chlorpromazine, when administered perinatally to rats is implicated in the production of both motor and behavioural deficits. In this study the effects of chlorpromazine on dendritic growth of cerebellar Purkinje cells were examined after administering the drug to litters of Long-Evans hooded rats fr... | 10.1159/000111622 | 3,678,107 | D000818:Animals; D002452:Cell Count; D002455:Cell Division; D002746:Chlorpromazine; D003712:Dendrites; D006098:Granulocytes; D011689:Purkinje Cells; D051381:Rats; D011919:Rats, Inbred Strains | Developmental neuroscience | 1,987 | D002746:Chlorpromazine |
Microscopic signature of metallic state in semicrystalline conjugated polymers doped with fluoroalkylsilane molecules. | Fluoroalkylsilane (FTS) acts as an efficient p-type dopant for organic semiconductors. FTS-doped films of the semicrystalline PBTTT polymer exhibit relatively high conductivities. We demonstrate that highly doped PBTTT films exhibit a metallic nature with clear Pauli paramagnetism as observed microscopically using elec... | 10.1002/adma.201304691 | 24,327,521 | Advanced materials (Deerfield Beach, Fla.) | 2,014 | ||
Advances in self-healing materials based on vascular networks with mechanical self-repair characteristics. | Here, we review the state-of-the-art in the field of engineered self-healing materials. These materials mimic the functionalities of various natural materials found in the human body (e.g., the healing of skin and bones by the vascular system). The fabrication methods used to produce these "vascular-system-like" engine... | 10.1016/j.cis.2017.12.010 | 29,329,666 | D000818:Animals; D040761:Biomimetic Materials; D001808:Blood Vessels; D006801:Humans; D008422:Materials Testing; D055595:Mechanical Phenomena | Advances in colloid and interface science | 2,018 | |
Meta Selective C-H Borylation of Sterically Biased and Unbiased Substrates Directed by Electrostatic Interaction. | An electrostatically directed meta borylation of sterically biased and unbiased substrates is described. The borylation follows an electrostatic interaction between the partially positive and negative charges between the ligand and substrate. With this strategy, it has been demonstrated that a wide number of challengin... | 10.1021/jacs.1c01770 | 33,988,369 | Journal of the American Chemical Society | 2,021 | ||
Comparison of ridge expansion and ridge splitting techniques for narrow alveolar ridge in a Swine cadaver model. | Ridge splitting and ridge expansion have been used to expand narrow alveolar ridges. Piezosurgical ridge splitting involves separating the atrophic crests with piezosurgical inserts. Ridge expansion with motor-driven expanders was proposed to achieve the cortical dilation. The purpose of this study was to evaluate the ... | 10.11607/prd.2269 | 25,909,532 | D000539:Alveolar Process; D000540:Alveolar Ridge Augmentation; D000818:Animals; D002102:Cadaver; D008334:Mandible; D059745:Piezosurgery; D013552:Swine | The International journal of periodontics & restorative dentistry | 2,015 | |
Antimicrobial and P450 inhibitory properties of common functional foods. | PURPOSE
To study the effect of functional foods on human cytochrome P450 (CYP) and the gut bacterial microflora that may potentially affect drug metabolism and ultimately affect human health and wellness.
METHODS
This study examined a variety of food plants from the Apiaceae, Fabaceae, and Lamiaceae families for thei... | 10.18433/j3p599 | 24,934,554 | D000900:Anti-Bacterial Agents; D019661:Apiaceae; D000077102:Apium; D028527:Cuminum; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System; D004305:Dose-Response Relationship, Drug; D030001:Foeniculum; D055951:Functional Food; D006801:Humans; D019686:Lamiaceae; D008826:Microbial Sensitivity ... | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques | 2,014 | D000900:Anti-Bacterial Agents; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System |
Selective steroid receptor modulators in reproductive medicine. | A key step forward in the treatment of hormone-dependent diseases has been made since the discovery of tissue-specific steroid receptor modulators (SRMs), or receptor ligands that elicit agonistic or antagonistic effects in a cell- and tissue-dependent manner. In reproductive medicine, selective estrogen receptors modu... | 26,200,398 | D001943:Breast Neoplasms; D004715:Endometriosis; D004717:Endometrium; D005260:Female; D006801:Humans; D011980:Receptors, Progesterone; D012098:Reproduction; D018456:Reproductive Medicine; D020845:Selective Estrogen Receptor Modulators | Minerva ginecologica | 2,015 | D011980:Receptors, Progesterone; D020845:Selective Estrogen Receptor Modulators | |
Child Sexual Abuse Revictimization: Child Demographics, Familial Psychosocial Factors, and Sexual Abuse Case Characteristics. | INTRODUCTION
The purposes of this study were to describe child demographics, familial psychosocial factors, and sexual abuse case characteristics in children experiencing sexual abuse revictimization before the age of 18 years, and to compare them with children not identified as experiencing revictimization.
METHOD
A... | 10.1097/JFN.0000000000000124 | 27,749,623 | D000293:Adolescent; D054523:Adult Survivors of Child Abuse; D000367:Age Factors; D002648:Child; D002650:Child Abuse, Sexual; D002675:Child, Preschool; D019548:Crime Victims; D057237:Criminals; D002658:Developmental Disabilities; D054541:Family Conflict; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Ne... | Journal of forensic nursing | 2,016 | |
Helminth mediated modulation of Type 1 diabetes (T1D). | Type 1 diabetes is increasing dramatically in incidence in the developed world. While there may be several reasons for this, improved sanitation and public health measures have altered our interactions with certain infectious agents such as helminths. There is increasing interest in the use of helminths or their produc... | 23,291,464 | D000818:Animals; D003922:Diabetes Mellitus, Type 1; D015801:Helminth Proteins; D006376:Helminths; D006801:Humans; D061147:Therapy with Helminths | International journal for parasitology | 2,013 | D015801:Helminth Proteins | |
Structure of the nucleocapsid protein of porcine reproductive and respiratory syndrome virus. | Porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped RNA virus of the Arteriviridae family, genomically related to the coronaviruses. PRRSV is the causative agent of both severe and persistent respiratory disease and reproductive failure in pigs worldwide. The PRRSV virion contains a core made of... | 10.1016/j.str.2003.09.018 | 14,604,534 | D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D018360:Crystallography, X-Ray; D019281:Dimerization; D004583:Electrons; D004926:Escherichia coli; D019143:Evolution, Molecular; D008958:Models, Molecular; D008969:Molecular Sequence Data; D019251:Nucleocapsid; D019590:Nucleocapsid Proteins; D016... | Structure (London, England : 1993) | 2,003 | D019590:Nucleocapsid Proteins |
A double blind randomized trial of wound infiltration with ropivacaine after breast cancer surgery with axillary nodes dissection. | BACKGROUND
The effect of local infiltration after breast surgery is controversial. This prospective double blind randomized study sought to document the analgesic effect of local anaesthetic infiltration after breast cancer surgery.
METHODS
Patients scheduled for mastectomy or tumorectomy and axillary nodes dissectio... | 10.1186/1471-2253-11-23 | 22,114,900 | BMC anesthesiology | 2,011 | ||
Care delivery considerations for widespread and equitable implementation of inherited cancer predisposition testing. | DNA sequencing advances through next-generation sequencing (NGS) and several practice changing events, have led to shifting paradigms for inherited cancer predisposition testing. These changes necessitated a means by which to maximize health benefits without unnecessarily inflating healthcare costs and exacerbating hea... | 10.1080/14737159.2017.1267567 | 27,910,721 | D003695:Delivery of Health Care; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D015894:Genome, Human; D055106:Genome-Wide Association Study; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D009369:Neoplasms | Expert review of molecular diagnostics | 2,017 | |
Twisted chimera states and multicore spiral chimera states on a two-dimensional torus. | Chimera states consisting of domains of coherently and incoherently oscillating oscillators in a two-dimensional periodic array of nonlocally coupled phase oscillators are studied. In addition to the one-dimensional chimera states familiar from one spatial dimension, two-dimensional structures termed twisted chimera st... | 10.1103/PhysRevE.92.042921 | 26,565,318 | Physical review. E, Statistical, nonlinear, and soft matter physics | 2,015 | ||
Chemical peel as an adjuvant treatment in pigmented contact dermatitis: a case series. | A chemical peel is chemexfoliation, a process of application of a chemical substance to the skin that causes controlled chemical destruction of the epidermis with or without part of the dermis leading to skin regeneration and remodeling. It can be classified depending upon the depth of penetration into superficial, med... | 10.1080/14764172.2022.2147953 | 36,384,385 | D006801:Humans; D002615:Chemexfoliation; D003869:Dermabrasion; D003877:Dermatitis, Contact; D008548:Melanosis; D000152:Acne Vulgaris; D010859:Pigmentation Disorders | Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology | 2,022 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.