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Mechanisms of memory enhancement. | The ongoing quest for memory enhancement is one that grows necessary as the global population increasingly ages. The extraordinary progress that has been made in the past few decades elucidating the underlying mechanisms of how long-term memories are formed has provided insight into how memories might also be enhanced.... | 10.1002/wsbm.1196 | 23,151,999 | D000818:Animals; D015928:Cognitive Behavioral Therapy; D005081:Exercise Therapy; D006801:Humans; D008568:Memory; D008569:Memory Disorders; D018377:Neurotransmitter Agents | Wiley interdisciplinary reviews. Systems biology and medicine | 2,013 | D018377:Neurotransmitter Agents |
Psychotherapeutic interventions at the end of life: a focus on meaning and spirituality. | Medical and psychological discourse on end-of-life care has steadily shifted over the years from focusing primarily on symptom control and pain management to incorporating more person-centred approaches to patient care. Such approaches underscore the significance of spirituality and meaning making as important resource... | 10.1177/070674370404900605 | 15,283,531 | D001293:Attitude to Death; D005086:Existentialism; D006801:Humans; D009369:Neoplasms; D010166:Palliative Care; D011613:Psychotherapy; D011788:Quality of Life; D026443:Spiritual Therapies; D013727:Terminal Care | Canadian journal of psychiatry. Revue canadienne de psychiatrie | 2,004 | |
Chfr interacts and colocalizes with TCTP to the mitotic spindle. | Chfr is a checkpoint protein that plays an important function in cell cycle progression and tumor suppression, although its exact role and regulation are unclear. Previous studies have utilized overexpression of Chfr to determine the signaling pathway of this protein in vivo. In this study, we demonstrate, by using thr... | 10.1038/onc.2008.167 | 18,504,434 | D000818:Animals; D014408:Biomarkers, Tumor; D002453:Cell Cycle; D018797:Cell Cycle Proteins; D006367:HeLa Cells; D006801:Humans; D008870:Microtubules; D009363:Neoplasm Proteins; D010766:Phosphorylation; D000075223:Poly-ADP-Ribose Binding Proteins; D008941:Spindle Apparatus; D014404:Tubulin; D000090324:Tumor Protein, Tr... | Oncogene | 2,008 | D014408:Biomarkers, Tumor; D018797:Cell Cycle Proteins; D009363:Neoplasm Proteins; D000075223:Poly-ADP-Ribose Binding Proteins; C000715647:TPT1 protein, human; D014404:Tubulin; D000090324:Tumor Protein, Translationally-Controlled 1; C412002:CHFR protein, human; D044767:Ubiquitin-Protein Ligases |
Somatosensory properties of the inferior olive of the cat. | We examined the somatosensory properties of 391 neurons in the inferior olive in 20 cats that were anesthetized with barbiturate or decerebrated. A response consisted of a single spike with a variable number of wavelets followed by a long refractory period. Neurons responsive to natural somatosensory stimuli were recor... | 10.1002/cne.902150210 | 6,853,776 | D000344:Afferent Pathways; D000818:Animals; D001307:Auditory Perception; D001931:Brain Mapping; D002415:Cats; D002525:Cerebellar Cortex; D004597:Electroshock; D005071:Evoked Potentials; D009847:Olivary Nucleus; D011930:Reaction Time; D012677:Sensation; D014796:Visual Perception | The Journal of comparative neurology | 1,983 | |
Differential effects of oral losartan and enalapril on local venous and systemic pressor responses to angiotensin I and II in healthy men. | This double-blind, placebo-controlled crossover study was designed to differentiate the pharmacodynamic effects of the angiotensin II receptor antagonist losartan from the angiotensin converting enzyme inhibitor enalapril. Effects of placebo, enalapril (10 mg), and losartan (20 and 100 mg) on local venous and systemic ... | 10.1016/S0009-9236(96)90026-0 | 8,549,037 | D000284:Administration, Oral; D000328:Adult; D000803:Angiotensin I; D000804:Angiotensin II; D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D001713:Biphenyl Compounds; D001794:Blood Pressure; D018592:Cross-Over Studies; D004311:Double-Blind Me... | Clinical pharmacology and therapeutics | 1,996 | D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D001713:Biphenyl Compounds; D007093:Imidazoles; D013777:Tetrazoles; D000804:Angiotensin II; D004656:Enalapril; D000803:Angiotensin I; D012083:Renin; D019808:Losartan |
Canadian clinical practice guidelines for acute and chronic rhinosinusitis. | This document provides healthcare practitioners with information regarding the management of acute rhinosinusitis (ARS) and chronic rhinosinusitis (CRS) to enable them to better meet the needs of this patient population. These guidelines describe controversies in the management of acute bacterial rhinosinusitis (ABRS) ... | 10.1186/1710-1492-7-2 | 21,310,056 | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology | 2,011 | ||
Inverted Takotsubo contractile pattern caused by pheochromocytoma with tall upright T-waves, but not typical deep T-wave inversion. | We describe a 36-year-old woman with inverted Takotsubo cardiomyopathy caused by pheochromocytoma crisis. In the acute phase, her electrocardiogram showed ST segment depression in lead II, III, aVF and V2 through V5. On day 14, tall upright T-waves were observed in leads V2 through V5 despite heart failure and basal to... | 10.1016/j.ijcard.2008.06.073 | 18,722,026 | D000208:Acute Disease; D000310:Adrenal Gland Neoplasms; D000328:Adult; D004562:Electrocardiography; D005260:Female; D006801:Humans; D010673:Pheochromocytoma; D054549:Takotsubo Cardiomyopathy; D014057:Tomography, X-Ray Computed | International journal of cardiology | 2,010 | |
Propolis from the northwest of Argentina as a source of antifungal principles. | AIMS
To determine the antimycotic and cytotoxic activities of partially purified propolis extract on yeasts, xylophagous and phytopathogenic fungi. To compare these activities with pinocembrin and galangin isolated from this propolis and with the synthetic drugs ketoconazole and clortrimazole.
METHODS AND RESULTS
Eth... | 10.1111/j.1365-2672.2006.02904.x | 16,834,596 | D000383:Agriculture; D000818:Animals; D000935:Antifungal Agents; D001118:Argentina; D002851:Chromatography, High Pressure Liquid; D044950:Flavanones; D005419:Flavonoids; D007218:Industrial Microbiology; D007928:Lethal Dose 50; D008826:Microbial Sensitivity Tests; D010935:Plant Diseases; D011429:Propolis; D013053:Spectr... | Journal of applied microbiology | 2,006 | D000935:Antifungal Agents; D044950:Flavanones; D005419:Flavonoids; C037032:galangin; C016063:pinocembrin; D011429:Propolis |
Ortho-vanillin nanoparticle-doped glucan microspheres exacerbate the anti-arthritic effects of methotrexate in adjuvant-induced arthritis in rats. | BACKGROUND
Methotrexate (MTX) commonly used in rheumatoid arthritis (RA) has severe adverse effects. Ortho-vanillin, an inhibitor of Toll-like receptors (TLR), can prevent inflammation. Glucan is a cereal fiber recognized by dectin-1 or β-glucan receptors of phagocytic macrophages. The purpose of the current project wa... | 10.1007/s43440-020-00099-x | 32,274,768 | D000818:Animals; D001169:Arthritis, Experimental; D001547:Benzaldehydes; D004339:Drug Compounding; D065546:Drug Liberation; D004359:Drug Therapy, Combination; D005936:Glucans; D008297:Male; D008727:Methotrexate; D008863:Microspheres; D053758:Nanoparticles; D051381:Rats; D017208:Rats, Wistar | Pharmacological reports : PR | 2,020 | D001547:Benzaldehydes; D005936:Glucans; C100058:vanillin; D008727:Methotrexate |
Walking ability of stroke patients: efficacy of tibial nerve blocking and a polypropylene ankle-foot orthosis. | OBJECTIVE
To investigate the efficacy of tibial nerve blocking by percutaneous radiofrequency thermocoagulation and an ankle-foot orthosis on the walking ability of stroke patients with a spastic equinus or equinovarus foot.
DESIGN
A placebo-controlled randomized clinical trial with a 2 x 2 factorial design and with ... | 10.1016/s0003-9993(96)90138-0 | 8,931,526 | D000293:Adolescent; D000328:Adult; D000368:Aged; D017115:Catheter Ablation; D002561:Cerebrovascular Disorders; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009407:Nerve Block; D009989:Orthotic Devices; D017063:Outcome Assessment, Health Care; D010349:Patient Complia... | Archives of physical medicine and rehabilitation | 1,996 | |
Gonadotropin-releasing hormone enhances the calving rate of beef females administered norgestomet and alfaprostol for estrus synchronization. | One hundred fifty beef heifers and 403 beef cows suckling calves were administered norgestomet implants (8 d) and alfaprostol, a PGF2 alpha analogue, approximately 28 h before implant removal. Thirty hours after implant removal, females were administered either GnRH via injection, GnRH via implantation, or no GnRH. The... | 10.2527/1997.754897x | 9,110,199 | D000818:Animals; D002417:Cattle; D004343:Drug Implants; D004973:Estrus Synchronization; D005260:Female; D007987:Gonadotropin-Releasing Hormone; D007273:Injections, Intramuscular; D008183:Luteal Phase; D007986:Luteinizing Hormone; D010060:Ovulation; D011247:Pregnancy; D018873:Pregnancy Rate; D011282:Pregnenediones; D045... | Journal of animal science | 1,997 | D004343:Drug Implants; D011282:Pregnenediones; D045167:Progesterone Congeners; D011460:Prostaglandins F; D007987:Gonadotropin-Releasing Hormone; C100284:norgestomet; C038354:alfaprostol; D007986:Luteinizing Hormone |
Structure of the mannose-rich oligosaccharide chains of concanavalin A-binding glycopeptides derived from beef brain glycoproteins. | A neutral, mannose-rich, concanavalin A (Con A)-binding glycopeptide fraction was obtained by proteolytic digestion of defatted beef brain tissue. Hydrazinolysis followed by gel filtration of the reaction products provided three oligosaccharides. A portion of each oligosaccharide was treated by exhaustive digestion wit... | 10.1111/j.1471-4159.1983.tb04746.x | 6,875,540 | D000818:Animals; D001923:Brain Chemistry; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002417:Cattle; D002846:Chromatography, Affinity; D002849:Chromatography, Gas; D008401:Gas Chromatography-Mass Spectrometry; D006020:Glycopeptides; D006023:Glycoproteins; D008358:Mannose; D009844:Oligosaccharides... | Journal of neurochemistry | 1,983 | D006020:Glycopeptides; D006023:Glycoproteins; D009844:Oligosaccharides; D011952:Receptors, Concanavalin A; C027774:concanavalin A-binding glycoproteins; D008358:Mannose |
Cell-autonomous beta-catenin signaling regulates cortical precursor proliferation. | Overexpression of beta-catenin, a protein that functions in both cell adhesion and signaling, causes expansion of the cerebral cortical precursor population and cortical surface area enlargement. Here, we find that focal elimination of beta-catenin from cortical neural precursors in vivo causes premature neuronal diffe... | 10.1523/JNEUROSCI.3180-06.2006 | 17,135,424 | D000818:Animals; D002454:Cell Differentiation; D049109:Cell Proliferation; D002478:Cells, Cultured; D002540:Cerebral Cortex; D005260:Female; D051379:Mice; D008822:Mice, Transgenic; D011247:Pregnancy; D015398:Signal Transduction; D013234:Stem Cells; D051176:beta Catenin | The Journal of neuroscience : the official journal of the Society for Neuroscience | 2,006 | D051176:beta Catenin |
Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releasing hormone mRNAs in mouse hypothalamus. | It is well documented that oestrogen suppresses food intake by an action at the hypothalamic level. Using in situ hybridisation, we studied the effect of castration (CX) and short-term administration of oestradiol (E2) in CX female mice for three neuropeptides involved in feeding behaviour: two anorexigenic peptides, (... | 10.1111/j.1365-2826.2007.01548.x | 17,388,940 | D000818:Animals; D001069:Appetite Regulation; D003346:Corticotropin-Releasing Hormone; D004958:Estradiol; D005260:Female; D007031:Hypothalamus; D051379:Mice; D008810:Mice, Inbred C57BL; D009474:Neurons; D009478:Neuropeptide Y; D011333:Pro-Opiomelanocortin; D012333:RNA, Messenger | Journal of neuroendocrinology | 2,007 | D009478:Neuropeptide Y; D012333:RNA, Messenger; D004958:Estradiol; D011333:Pro-Opiomelanocortin; D003346:Corticotropin-Releasing Hormone |
Comparison of femtosecond laser and continuous wave UV sources for protein-nucleic acid crosslinking. | Crosslinking proteins to the nucleic acids they bind affords stable access to otherwise transient regulatory interactions. Photochemical crosslinking provides an attractive alternative to formaldehyde-based protocols, but irradiation with conventional UV sources typically yields inadequate product amounts. Crosslinking... | 10.1111/j.1751-1097.2007.00179.x | 18,028,214 | D003432:Cross-Linking Reagents; D004249:DNA Damage; D007834:Lasers; D015394:Molecular Structure; D010777:Photochemistry; D017319:Photosensitizing Agents; D011485:Protein Binding; D011506:Proteins; D012441:Saccharomyces cerevisiae; D035181:TATA-Box Binding Protein; D013997:Time Factors; D014466:Ultraviolet Rays | Photochemistry and photobiology | 2,007 | D003432:Cross-Linking Reagents; D017319:Photosensitizing Agents; D011506:Proteins; D035181:TATA-Box Binding Protein |
Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots. | CONTEXT
Fat distribution differs in men and women, but in both sexes, a predominantly gluteal-femoral compared with abdominal (central) fat distribution is associated with lower metabolic risk. Differences in cellular characteristics and metabolic functions of these depots have been described, but the molecular mechani... | 10.1210/jc.2012-2953 | 23,150,689 | D050153:Abdominal Fat; D000293:Adolescent; D000328:Adult; D001823:Body Composition; D002081:Buttocks; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D008297:Male; D009765:Obesity; D012727:Sex Characteristics; D050151:Subcutaneous Fat; D059467:Transcriptome; D055815:Young Adult | The Journal of clinical endocrinology and metabolism | 2,013 | |
Self-Powered, High-Speed and Visible-Near Infrared Response of MoO(3-x)/n-Si Heterojunction Photodetector with Enhanced Performance by Interfacial Engineering. | Photodetectors with a wide spectrum response are important components for sensing, imaging, and other optoelectronic applications. A molybdenum oxide (MoO(3-x))/Si heterojunction has been applied as solar cells with great success, but its potential in photodetectors has not been explored yet. Herein, a self-powered, hi... | 10.1021/acsami.5b09492 | 26,544,078 | ACS applied materials & interfaces | 2,015 | ||
Advances in Osteometric Sorting: Utilizing Diaphyseal CSG Properties for Lower Limb Skeletal Pair-Matching. | Pair-matching of bilateral elements is a major component of resolving commingled remains both in forensic and bioarchaeological contexts. This study presents a new method of osteometric pair-matching of the lower limbs which relies on 3D digital models of the femur and tibia bones. The proposed method, which is accompa... | 10.1111/1556-4029.14480 | 32,569,430 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003198:Computer Simulation; D018483:Diaphyses; D005260:Female; D005269:Femur; D018732:Forensic Anthropology; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D013977:Tibia; D05... | Journal of forensic sciences | 2,020 | |
Dissociation Pathways of the p53 DNA Binding Domain from DNA and Critical Roles of Key Residues Elucidated by dPaCS-MD/MSM. | p53 is a transcriptional factor that regulates cell response to a variety of stresses. About a half of all human tumors contain p53 mutations, and the accumulation of mutations in the DNA binding domain of p53 (p53-DBD) can cause destabilization of p53 and its complex with DNA. To identify the key residues of the p53-D... | 10.1021/acs.jcim.1c01508 | 35,234,033 | D004247:DNA; D006801:Humans; D056004:Molecular Dynamics Simulation; D011485:Protein Binding; D000072417:Protein Domains; D016159:Tumor Suppressor Protein p53 | Journal of chemical information and modeling | 2,022 | D016159:Tumor Suppressor Protein p53; D004247:DNA |
Reduced local segregation of single-subject gray matter networks in adult PTSD. | To psychoradiologically investigate the topological organization of single-subject gray matter networks in patients with PTSD. Eighty-nine adult PTSD patients and 88 trauma-exposed controls (TEC) underwent a structural T1 magnetic resonance imaging scan. The single-subject brain structural networks were constructed bas... | 10.1002/hbm.24330 | 30,096,216 | D000328:Adult; D002540:Cerebral Cortex; D005260:Female; D066128:Gray Matter; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009415:Nerve Net; D000067073:Psychological Trauma; D013313:Stress Disorders, Post-Traumatic | Human brain mapping | 2,018 | |
B-cell-specific transgene expression using a self-inactivating retroviral vector with human CD19 promoter and viral post-transcriptional regulatory element. | Retroviral gene transfer resulting in transgene expression selectively restricted to specific cell lineages would be desirable for many gene therapeutic applications. Such transcriptional targeting of retroviruses can be accomplished by employing eukaryotic control elements in self-inactivating (SIN) retroviral vectors... | 10.1038/sj.gt.3302255 | 15,029,232 | D000818:Animals; D018941:Antigens, CD19; D001402:B-Lymphocytes; D005434:Flow Cytometry; D015870:Gene Expression; D018390:Gene Targeting; D015316:Genetic Therapy; D005822:Genetic Vectors; D017919:Hepatitis B Virus, Woodchuck; D006801:Humans; D011401:Promoter Regions, Genetic; D012190:Retroviridae; D014158:Transcription,... | Gene therapy | 2,004 | D018941:Antigens, CD19; D054334:Viral Regulatory and Accessory Proteins |
Medical consequences and associations with untreated sleep-related breathing disorders and outcomes of treatments. | Sleep-related breathing disorders are a broad group of disorders that include obstructive sleep apnea, central sleep apnea, and periodic breathing disorders. This article reviews the scientific literature that links SRBD to various medical conditions including hypertension, coronary artery disease, cardiac arrhythmias,... | 22,416,633 | D001145:Arrhythmias, Cardiac; D003324:Coronary Artery Disease; D003863:Depression; D003920:Diabetes Mellitus; D006801:Humans; D006973:Hypertension; D009765:Obesity; D012891:Sleep Apnea Syndromes; D020182:Sleep Apnea, Central; D020181:Sleep Apnea, Obstructive; D020521:Stroke; D016896:Treatment Outcome | Journal of the California Dental Association | 2,012 | ||
Timeliness of data sources used for influenza surveillance. | OBJECTIVE
In recent years, influenza surveillance data has expanded to include alternative sources such as emergency department data, absenteeism reports, pharmaceutical sales, website access and health advice calls. This study presents a review of alternative data sources for influenza surveillance, summarizes the tim... | 10.1197/jamia.M2328 | 17,600,101 | D000465:Algorithms; D016000:Cluster Analysis; D004196:Disease Outbreaks; D004636:Emergency Service, Hospital; D006801:Humans; D007251:Influenza, Human; D011159:Population Surveillance; D013997:Time Factors | Journal of the American Medical Informatics Association : JAMIA | 2,007 | |
Fiber-reinforced fixed partial dentures: a preliminary retrospective clinical study. | The aim of this study was to evaluate the clinical performance (retention rate) of fiber-reinforced composite fixed partial dentures (FPDs). Polyethylene fiber (Ribbond) was used combined with restorative composite during FPDs fabrication. FPDs were placed in thirteen patients in a private clinic. Nineteen FPDs were ev... | 19,089,039 | Journal of applied oral science : revista FOB | 2,006 | |||
Recovery of Zinc and Iron from Steel Mill Dust-An Overview of Available Technologies. | The global shortage of zinc mines makes the extraction of zinc from zinc-containing wastes a hot research topic. Most kinds of steel mill dust (SMD) cannot be directly returned to the ironmaking and steelmaking processes due to their zinc content. A large amount of SMD produced during steelmaking has become a major cha... | 10.3390/ma15124127 | 35,744,185 | Materials (Basel, Switzerland) | 2,022 | ||
Chromosomal transformation in Bacillus subtilis is a non-polar recombination reaction. | Natural chromosomal transformation is one of the primary driving forces of bacterial evolution. This reaction involves the recombination of the internalized linear single-stranded (ss) DNA with the homologous resident duplex via RecA-mediated integration in concert with SsbA and DprA or RecO. We show that sequence dive... | 10.1093/nar/gkv1546 | 26,786,319 | D001412:Bacillus subtilis; D001426:Bacterial Proteins; D002876:Chromosomes, Bacterial; D004269:DNA, Bacterial; D004270:DNA, Circular; D004277:DNA, Single-Stranded; D004926:Escherichia coli; D015870:Gene Expression; D008565:Membrane Proteins; D011938:Rec A Recombinases; D011994:Recombinant Proteins; D011995:Recombinatio... | Nucleic acids research | 2,016 | D001426:Bacterial Proteins; D004269:DNA, Bacterial; D004270:DNA, Circular; D004277:DNA, Single-Stranded; C093815:DprA protein, bacteria; D008565:Membrane Proteins; D011994:Recombinant Proteins; D011938:Rec A Recombinases |
Spina bifida. | Spina bifida is a birth defect in which the vertebral column is open, often with spinal cord involvement. The most clinically significant subtype is myelomeningocele (open spina bifida), which is a condition characterized by failure of the lumbosacral spinal neural tube to close during embryonic development. The expose... | 10.1038/nrdp.2015.7 | 27,189,655 | D005260:Female; D005492:Folic Acid; D006801:Humans; D008591:Meningomyelocele; D011247:Pregnancy; D011295:Prenatal Care; D011296:Prenatal Diagnosis; D016135:Spinal Dysraphism | Nature reviews. Disease primers | 2,015 | D005492:Folic Acid |
A Comparative Study of Collagen Dressing versus Petrolatum Gauze Dressing in reducing Pain at the Donor Area. | BACKGROUND
Skin graft is one of the commonly done procedures by plastic surgeons, dermato surgeons and general surgeons. Pain at the donor area is a common complaint by the patient. The skin graft donor site area is usually covered with petrolatum dressing dermatosurgeons.
AIM
This study was done to compare collagen ... | 10.4103/JCAS.JCAS_110_16 | 28,529,416 | Journal of cutaneous and aesthetic surgery | 2,017 | ||
Micro-CT evaluation of microleakage under orthodontic ceramic brackets bonded with different bonding techniques and adhesives. | AIM
The aim of this study was to evaluate microleakage under orthodontic ceramic brackets bonded with direct and different indirect bonding techniques and adhesives using micro-computed tomography.
MATERIALS AND METHODS
A total of 30 human maxillary premolars were randomly separated into five groups with six teeth in... | 10.1093/ejo/cjv023 | 25,855,655 | D001641:Bicuspid; D017438:Bisphenol A-Glycidyl Methacrylate; D002516:Ceramics; D001840:Dental Bonding; D003763:Dental Leakage; D003764:Dental Materials; D006801:Humans; D055115:Light-Curing of Dental Adhesives; D008422:Materials Testing; D008689:Methacrylates; D016382:Orthodontic Appliance Design; D016910:Orthodontic B... | European journal of orthodontics | 2,016 | D003764:Dental Materials; D008689:Methacrylates; D011109:Polymethacrylic Acids; D019279:Resin Cements; C477791:Sondhi Indirect Bonding Resin; C477790:Transbond XT; C487385:custom I.Q. sealant; C065742:Transbond; C020946:triethylene glycol dimethacrylate; D011092:Polyethylene Glycols; C074277:ethoxylated bis-phenol A di... |
[Anesthesia, department of anesthesiology and anesthesiology--why has anesthesiology not been accepted socially in Japan?]. | An incorrect Japanese terminology of "Masuigaku [symbol: see text]" has been used widely to express "anesthesiology" or "anaesthetics" [symbol: see text] since the first Department of Anesthesiology was established in Tokyo University in 1952. The reason why the nomenclature "Masui-gaku" is wrong is as follows: Japanes... | 10,707,528 | D000761:Anesthesia Department, Hospital; D000776:Anesthesiology; D006801:Humans; D007564:Japan; D009626:Terminology as Topic | Masui. The Japanese journal of anesthesiology | 2,000 | ||
Structural features of the minimal DNA binding domain (M98-F219) of human nucleotide excision repair protein XPA. | XPA, an essential protein in nucleotide excision repair (NER), interacts with damaged DNA and other proteins (RPA, ERCC1 and TFIIH) to remove a wide variety of chemically and structurally distinct DNA lesions from the eukaryotic genome. To understand the structural basis for the role of XPA in the repair process, the s... | 10.1093/nar/26.11.2779 | 9,592,168 | D000595:Amino Acid Sequence; D001665:Binding Sites; D004268:DNA-Binding Proteins; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D019906:Nuclear Magnetic Resonance, Biomolecular; D011487:Protein Conformation; D011993:Recombinant Fusion Proteins; D013329:Structure-Activity Relationship; D051... | Nucleic acids research | 1,998 | D004268:DNA-Binding Proteins; D011993:Recombinant Fusion Proteins; C497314:XPA protein, human; D051760:Xeroderma Pigmentosum Group A Protein |
Length of attending-student and resident-student interactions in the inpatient medicine clerkship. | UNLABELLED
PHENOMENON: Changes in the medical education milieu have led away from the apprenticeship model resulting in shorter physician-student interactions. Faculty and student feedback suggests that supervisor/student interactions may now be more cursory with increasing numbers of supervisors per student, and short... | 10.1080/10401334.2015.1011655 | 25,893,934 | D001900:Boston; D002982:Clinical Clerkship; D002983:Clinical Competence; D004504:Education, Medical, Undergraduate; D004521:Educational Measurement; D005260:Female; D006801:Humans; D007396:Internship and Residency; D007400:Interprofessional Relations; D008297:Male; D010348:Patient Care Team; D013337:Students, Medical; ... | Teaching and learning in medicine | 2,015 | |
Lived experiences of Iranian parents of beta-thalassemia children. | INTRODUCTION
Thalassemia is a chronic blood disease, which imposes adverse effects on patients and their families. Parents of such patients, given that they had the thalassemia trait, hold themselves responsible for their children's disease in addition to other difficulties, bear the burden of guilt and hopelessness an... | 10.2147/JMDH.S132848 | 28,721,064 | Journal of multidisciplinary healthcare | 2,017 | ||
Myocardial Injury on Admission as a Risk in Critically Ill COVID-19 Patients: A Retrospective in-ICU Study. | OBJECTIVE
The aim of this study was to investigate the incidence, clinical presentation, cardiovascular (CV) complications, and mortality risk of myocardial injury on admission in critically ill intensive care unit (ICU) inpatients with COVID-19.
DESIGN
A single-center, retrospective, observational study.
SETTING
A... | 10.1053/j.jvca.2020.10.019 | 33,162,306 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000086382:COVID-19; D002318:Cardiovascular Diseases; D016638:Critical Illness; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D012189:Retrospective Studies; D012307:Risk Factors | Journal of cardiothoracic and vascular anesthesia | 2,021 | |
An enhancer region within the copia untranslated leader contains binding sites for Drosophila regulatory proteins. | The untranslated leader region (ULR) of the Drosophila LTR retrotransposon copia is known to be critical to the element's expression in a variety of species. Two copia ULR size variants are prevalent in natural populations. The more transcriptionally active full length variants contain within their ULRs two tandemly re... | 10.1016/s0378-1119(98)00048-1 | 9,524,274 | D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D002460:Cell Line; D002467:Cell Nucleus; D015500:Chloramphenicol O-Acetyltransferase; D004268:DNA-Binding Proteins; D004331:Drosophila melanogaster; D004625:Embryo, Nonmammalian; D004742:Enhancer Elements, Genetic; D005260:Female; D017930:Genes, Reporter; D... | Gene | 1,998 | D004268:DNA-Binding Proteins; D011993:Recombinant Fusion Proteins; D018626:Retroelements; D015500:Chloramphenicol O-Acetyltransferase |
Spectrophotometric studies of a novel Gedunin-2-Hydroxypropyl- β-cyclodextrin binary system. | BACKGROUND
Gedunin, a limonoid, is linked with antimalarial, anticancer and anti-allergic activities. This study was aimed at preparing an inclusion complex of gedunin and 2-hydroxypropyl-p-cyclodextrin (HBD) to increase solubility of-gedunin in polar solvents which will increase absorption and bioavailability in vivo ... | 29,465,859 | D000073738:2-Hydroxypropyl-beta-cyclodextrin; D006801:Humans; D036701:Limonins; D009682:Magnetic Resonance Spectroscopy; D012995:Solubility; D012997:Solvents; D013053:Spectrophotometry | African journal of medicine and medical sciences | 2,016 | D036701:Limonins; D012997:Solvents; D000073738:2-Hydroxypropyl-beta-cyclodextrin; C106014:gedunin | |
Extracting Knowledge from MS Clinical Metabolomic Data: Processing and Analysis Strategies. | Assessing potential alterations of metabolic pathways using large-scale approaches today plays a central role in clinical research. Because several thousands of mass features can be measured for each sample with separation techniques hyphenated to mass spectrometry (MS) detection, adapted strategies should be implement... | 10.1007/978-1-4939-7592-1_28 | 29,363,089 | D000465:Algorithms; D015415:Biomarkers; D002851:Chromatography, High Pressure Liquid; D019295:Computational Biology; D004147:Dioxins; D006801:Humans; D008297:Male; D013058:Mass Spectrometry; D053858:Metabolic Networks and Pathways; D055432:Metabolomics; D015233:Models, Statistical; D057188:Workflow | Methods in molecular biology (Clifton, N.J.) | 2,018 | D015415:Biomarkers; D004147:Dioxins |
Risk factors associated with the death of patients hospitalized for juvenile systemic lupus erythematosus. | We assessed the risk factors associated with death in patients hospitalized for juvenile systemic lupus erythematosus (JSLE) and evaluated the autopsy reports. A total of 57,159 hospitalizations occurred in our institution from 1994 to 2003, 169 of them involving 71 patients with JSLE. The most recent hospitalization o... | 10.1590/s0100-879x2006005000110 | 17,653,454 | D000293:Adolescent; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008180:Lupus Erythematosus, Systemic; D008297:Male; D015999:Multivariate Analysis; D012307:Risk Factors; D018805:Sepsis; D012720:Severity of Illness Index | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas | 2,007 | |
Alterations of the Fhit gene in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats. | The present study was conducted to assess whether Fhit gene alterations are a feature of hepatocellular carcinomas (HCCs) induced by N-nitrosodiethylamine (DEN) in male Fischer 344 rats. Animals, 6 wk old, received a single intraperitoneal injection of DEN at a dose of 10 mg/kg body weight, followed by combined treatme... | 10.1002/mc.10044 | 12,112,319 | D017766:Acid Anhydride Hydrolases; D000818:Animals; D001483:Base Sequence; D015153:Blotting, Western; D002273:Carcinogens; D017931:DNA Primers; D004052:Diethylnitrosamine; D008114:Liver Neoplasms, Experimental; D008297:Male; D009363:Neoplasm Proteins; D051381:Rats; D011916:Rats, Inbred F344; D020133:Reverse Transcripta... | Molecular carcinogenesis | 2,002 | D002273:Carcinogens; D017931:DNA Primers; D009363:Neoplasm Proteins; C099814:fragile histidine triad protein; D004052:Diethylnitrosamine; D017766:Acid Anhydride Hydrolases |
The role of cyclone activity in snow accumulation on Arctic sea ice. | Identifying the mechanisms controlling the timing and magnitude of snow accumulation on sea ice is crucial for understanding snow's net effect on the surface energy budget and sea-ice mass balance. Here, we analyze the role of cyclone activity on the seasonal buildup of snow on Arctic sea ice using model, satellite, an... | 10.1038/s41467-019-13299-8 | 31,754,115 | Nature communications | 2,019 | ||
Unconventional magnetization textures and domain-wall pinning in Sm-Co magnets. | Some of the best-performing high-temperature magnets are Sm-Co-based alloys with a microstructure that comprises an [Formula: see text] matrix and magnetically hard [Formula: see text] cell walls. This generates a dense domain-wall-pinning network that endows the material with remarkable magnetic hardness. A precise un... | 10.1038/s41598-020-78010-0 | 33,273,594 | Scientific reports | 2,020 | ||
HIV-related bronchopulmonary infection by Pseudomonas aeruginosa in the HAART era: radiological findings. | PURPOSE
To evaluate whether highly active antiretroviral therapy (HAART) modifies radiographic appearances of Pseudomonas aeruginosa bronchopulmonary infection in HIV-infected patients. P. aeruginosa is increasingly reported as a respiratory pathogen in HIV+ patients with very low levels of CD4 lymphocytes. Few studies... | 10.1080/02841850600827569 | 17,050,357 | D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections; D006801:Humans; D008171:Lung Diseases; D008297:Male; D008875:Middle Aged; D011552:Pseudomonas Infections; D011859:Radiography; D012189:Retrospective Studies | Acta radiologica (Stockholm, Sweden : 1987) | 2,006 | |
Metabolomic responses to lumacaftor/ivacaftor in cystic fibrosis. | BACKGROUND
Cystic fibrosis (CF) is a life-limiting disease caused by a defect in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Lumacaftor/Ivacaftor is a novel CFTR modulator approved for patients that are homozygous for Phe508del CFTR, but its clinical effectiveness varies amongst patients, makin... | 10.1002/ppul.23972 | 29,461,009 | D000293:Adolescent; D000328:Adult; D000627:Aminophenols; D000631:Aminopyridines; D052117:Benzodioxoles; D015415:Biomarkers; D002853:Chromatography, Liquid; D003550:Cystic Fibrosis; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D0554... | Pediatric pulmonology | 2,018 | D000627:Aminophenols; D000631:Aminopyridines; D052117:Benzodioxoles; D015415:Biomarkers; C505032:CFTR protein, human; D004338:Drug Combinations; D015363:Quinolones; C000599212:lumacaftor, ivacaftor drug combination; D019005:Cystic Fibrosis Transmembrane Conductance Regulator |
Systemic drug-related intertriginous and flexural exanthema-like eruption after Oxford-AstraZeneca COVID-19 vaccine. | Systemic drug-related intertriginous and flexural exanthema (SDRIFE) is an adverse drug reaction which manifests as a symmetrical erythematous rash involving the skin folds after systemic drug exposure. A vast array of possible side effects associated with administration of different anti-SARS-CoV-2 vaccines have been ... | 10.1186/s12948-022-00179-8 | 36,503,530 | Clinical and molecular allergy : CMA | 2,022 | ||
Characterization of the C-terminal flanking peptide of human beta-preprotachykinin. | The nucleotide sequence of cDNA encoding the common biosynthetic precursor of substance P, neurokinin A and neuropeptide K (beta-preprotachykinin) predicts that, in the human, the precursor contains a C-terminal flanking peptide of 19 amino acid residues [beta-preprotachykinin(111-129)-peptide]. Using an antiserum rais... | 10.1016/0196-9781(90)90007-r | 2,284,201 | D000310:Adrenal Gland Neoplasms; D000595:Amino Acid Sequence; D006801:Humans; D008969:Molecular Sequence Data; D009363:Neoplasm Proteins; D010446:Peptide Fragments; D010673:Pheochromocytoma; D011498:Protein Precursors; D015320:Tachykinins | Peptides | 1,990 | D009363:Neoplasm Proteins; D010446:Peptide Fragments; D011498:Protein Precursors; D015320:Tachykinins; C044206:preprotachykinin; C067233:beta-preprotachykinin (111-126) |
Monochorionic versus dichorionic twins: Are obstetric outcomes always different? | This prospective cohort study compared obstetric, perinatal and postpartum outcomes of monochorionic diamniotic (n = 228) versus (vs.) dichorionic (n = 598) twin pregnancies. Statistical analysis was performed using software SPSS® v19.0.0.2. Chi square, Fischer's exact, Student's t and Mann-Withney tests were applied. ... | 10.3109/01443615.2015.1116501 | 27,013,084 | D000328:Adult; D036861:Delivery, Obstetric; D005260:Female; D005330:Fetofetal Transfusion; D005865:Gestational Age; D006760:Hospitalization; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D059285:Pregnancy, ... | Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology | 2,016 | |
The Role of Lactic Acid on Wound Healing, Cell Growth, Cell Cycle Kinetics, and Gene Expression of Cultured Junctional Epithelium Cells in the Pathophysiology of Periodontal Disease. | Lactic acid (LA) is short-chain fatty acid, such as butyric acid and propionic acid, that is produced as a metabolite of lactic acid bacteria, including periodontopathic bacteria. These short-chain fatty acids have positive effects on human health but can also have negative effects, such as the promotion of periodontal... | 10.3390/pathogens10111507 | 34,832,662 | Pathogens (Basel, Switzerland) | 2,021 | ||
The reliability of 99mmTc-pyrophosphate scintigraphy in the diagnosis of bony metastases. | A series of 183 patients suffering from cancer examined with 99mTc-yrophosphate scintigraphy is presented. Of the 74 cases with radiologically confirmed metastases or primary tumour in the skeleton 67 (91%) had an isotope accumulation. Four cases with false positive accumulations were detected. In three cases the uptak... | 883,754 | D001859:Bone Neoplasms; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D011877:Radionuclide Imaging; D013667:Technetium | Annals of clinical research | 1,977 | D013667:Technetium | |
Photodissociation Dynamics of OCS near 150 nm: The S(1S) and S(3P) Product Channels. | Vacuum ultraviolet photodissociation dynamics of carbonyl sulfide (OCS) was investigated by using the time-sliced velocity map ion imaging technique. Images of the S(1S) and S(3P) photofragments formed in the OCS photodissociation were acquired at six photolysis wavelengths from 147.24 to 156.48 nm. Vibrational states ... | 10.1021/acs.jpca.0c03823 | 32,663,027 | The journal of physical chemistry. A | 2,020 | ||
Predicting Attention-Shaping Response in People With Schizophrenia. | People with schizophrenia often experience attentional impairments that hinder learning during psychological interventions. Attention shaping is a behavioral technique that improves attentiveness in this population. Because reinforcement learning (RL) is thought to be the mechanism by which attention shaping operates, ... | 10.1097/NMD.0000000000001286 | 33,315,800 | D000328:Adult; D001288:Attention; D003071:Cognition; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D012054:Reinforcement, Psychology; D012559:Schizophrenia; D012565:Schizophrenic Psychology | The Journal of nervous and mental disease | 2,021 | |
Comparison between clinical diagnosis and CSF biomarkers of Alzheimer disease in elderly patients with late onset psychosis: Helsinki Old Age Psychosis Study (HOPS). | OBJECTIVES
To determine the proportion of elderly people with a first psychotic episode actually suffering from dementia, especially Alzheimer disease (AD), by using cerebrospinal fluid (CSF) biomarkers.
DESIGN
Prospective case-control study.
SETTING AND PARTICIPANTS
Sixty-six patients age 65 years and older with r... | 23,597,931 | D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease; D016229:Amyloid beta-Peptides; D015415:Biomarkers; D016022:Case-Control Studies; D005260:Female; D005387:Finland; D006801:Humans; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments; D011446:Prospective Studies; D011618:P... | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2,014 | D016229:Amyloid beta-Peptides; D015415:Biomarkers; D010446:Peptide Fragments; C075222:amyloid beta-protein (1-42); D016875:tau Proteins | |
[Polysaccharide additives in foods rich in proteins II. A simple, semi-quantitative technique of estimation (author's transl)]. | Samples of foods rich in protein, after removal of lipids and of proteins by enzymatic hydrolysis, are partially demineralized and concentrated. In the concentrate polysaccharides are detected and semi-quantitively estimated by performing the precipitations in graduated tubes, which are especially suitable for this pur... | 10.1007/BF01460023 | 1,210,788 | D011232:Chemical Precipitation; D004044:Dietary Proteins; D005503:Food Additives; D011134:Polysaccharides; D014462:Ultrafiltration | Zeitschrift fur Lebensmittel-Untersuchung und -Forschung | 1,975 | D004044:Dietary Proteins; D005503:Food Additives; D011134:Polysaccharides |
Different scaling and root planing strategies in Turkish patients with aggressive periodontitis: A randomized controlled clinical trial. | OBJECTIVES
The aim of this study was to compare clinical, cytokine and microbiological responses after quadrant-based scaling and root planing (Q-SRP), full-mouth SRP (FM-SRP) and full-mouth disinfection (FMD) in patients with generalized aggressive periodontitis (GAgP), which is currently termed as generalized stage-I... | 10.1111/idh.12592 | 35,143,714 | D010520:Aggressive Periodontitis; D001419:Bacteria; D055113:Chronic Periodontitis; D012534:Dental Scaling; D005883:Gingival Crevicular Fluid; D006801:Humans; D020381:Interleukin-17; D016745:Root Planing | International journal of dental hygiene | 2,022 | D020381:Interleukin-17 |
Efficiency and Quality of Data Collection Among Public Mental Health Surveys Conducted During the COVID-19 Pandemic: Systematic Review. | BACKGROUND
The World Health Organization has recognized the importance of assessing population-level mental health during the COVID-19 pandemic. During a global crisis such as the COVID-19 pandemic, a timely surveillance method is urgently needed to track the impact on public mental health.
OBJECTIVE
This brief syste... | 10.2196/25118 | 33,481,754 | D000086382:COVID-19; D003430:Cross-Sectional Studies; D003625:Data Collection; D006306:Health Surveys; D006801:Humans; D008603:Mental Health; D058873:Pandemics; D000086402:SARS-CoV-2 | Journal of medical Internet research | 2,021 | |
Epidemiology of hip fractures in Austria: evidence for a change in the secular trend. | UNLABELLED
Hip fracture incidence rates in Austria over a period of 20 years (1989-2008) were assessed. Age-standardized incidence rates increased until 2005 but decreased thereafter. This change in the secular trend was primarily driven by a decrease in hip fracture incidence in women.
INTRODUCTION
The aim of the pr... | 10.1007/s00198-010-1271-9 | 20,458,573 | D000368:Aged; D000369:Aged, 80 and over; D001317:Austria; D005260:Female; D006620:Hip Fractures; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA | 2,011 | |
Quinone profiles in lake sediments: Implications for microbial diversity and community structures. | Microbial quinone compositions of sediment mud samples from five different lakes in Japan were studied by spectrochromatography and mass spectrometry. The total quinone content of these samples ranged from 1.97 to 18.0 nmol/g dry weight of sediment, of which a combined fraction of ubiquinones and menaquinones accounted... | 10.2323/jgam.45.221 | 12,501,364 | The Journal of general and applied microbiology | 1,999 | ||
Sending your teenagers away. Controlled stress decreases neurotic vulnerability. | OBJECTIVE
To study the effect of a controlled stressor on the rate of personality maturity.
DESIGN
Eighteen-month prospective controlled study.
SETTING
General community.
INTERVENTION
EXPERIMENTAL
Exposed to the stress of 12 months' intercultural experience.
CONTROL
Remained in usual environment.
MAIN OUTC... | 10.1001/archpsyc.1993.01820190087009 | 8,317,952 | D000293:Adolescent; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007393:International Educational Exchange; D008297:Male; D009497:Neurotic Disorders; D010553:Personality Development; D011446:Prospective Studies; D012307:Risk Factors; D013315:Stress, Psychological; D013334:Students | Archives of general psychiatry | 1,993 | |
Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4). | OBJECTIVES
We sought to determine the effect of tezosentan in patients with acute decompensated heart failure (HF) associated with acute coronary syndrome (ACS).
BACKGROUND
Tezosentan is a dual endothelin receptor antagonist that has been shown to improve cardiac output, decrease pulmonary capillary wedge pressure, a... | 10.1016/s0735-1097(03)00194-3 | 12,742,280 | D000208:Acute Disease; D000368:Aged; D003327:Coronary Disease; D004311:Double-Blind Method; D005260:Female; D006333:Heart Failure; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D010865:Pilot Projects; D011725:Pyridines; D013577:Syndrome; D013... | Journal of the American College of Cardiology | 2,003 | D011725:Pyridines; D013777:Tetrazoles; D014665:Vasodilator Agents; C120582:tezosentan |
Reduction in basal ganglia and substantia nigra substance P levels in Huntington's disease. | Substance P (SP) levels were determined by radioimmunoassay (RIA) in several regions of post-mortem brain of controls and Huntington's disease (HD) patients. In controls, highest SP levels were found in basal ganglia, substantia nigra and hypothalamus. Nigral pars reticulata contained 3--4-fold higher levels than pars ... | 10.1016/0006-8993(81)90171-2 | 6,164,436 | D000368:Aged; D001479:Basal Ganglia; D001921:Brain; D006801:Humans; D006816:Huntington Disease; D008875:Middle Aged; D009474:Neurons; D013373:Substance P; D013378:Substantia Nigra | Brain research | 1,981 | D013373:Substance P |
Giant abdominal tumor of the ovary. | A giant abdominal tumor can exert a mass effect on surrounding structures. We report here a 34-year-old single female who presented with an increased abdominal girth and was subsequently found to have a giant abdominal mass. Large volume aspiration (85 L) at a slow rate (1 L/min) was initially performed before surgical... | 10.1111/j.1447-0756.2007.00711.x | 18,226,141 | D000328:Adult; D018293:Cystadenoma, Serous; D003937:Diagnosis, Differential; D005187:Fallopian Tubes; D005260:Female; D006801:Humans; D007022:Hypotension; D010051:Ovarian Neoplasms; D010052:Ovariectomy; D014619:Vacuum Curettage | The journal of obstetrics and gynaecology research | 2,008 | |
Numerical intuitions in infancy: Give credit where credit is due. | Leibovich et al. overlook numerous human infant studies pointing to an early emerging number sense. These studies have carefully manipulated continuous magnitudes in the context of a numerical task revealing that infants can discriminate number when extent is controlled, that infants fail to track extent cues with prec... | 10.1017/S0140525X16002272 | 29,342,635 | D002657:Child Development; D003071:Cognition; D006801:Humans; D007223:Infant; D019545:Intuition | The Behavioral and brain sciences | 2,017 | |
Microbial Community Structure and Functional Potential Along a Hypersaline Gradient. | Salinity is one of the strongest environmental drivers of microbial evolution and community composition. Here we aimed to determine the impact of salt concentrations (2.5, 7.5, and 33.2%) on the microbial community structure of reclaimed saltern ponds near San Francisco, California, and to discover prospective enzymes ... | 10.3389/fmicb.2018.01492 | 30,042,744 | Frontiers in microbiology | 2,018 | ||
Standardised spider (Arachnida, Araneae) inventory of Lammi, Finland. | BACKGROUND
In June 2019, an ecology field course of the University of Helsinki was held at Lammi Biological Station, Southern Finland. Within this course, the students familiarised themselves with field work and identification of spiders and explored the diversity of species in the area. Three sampling plots were chose... | 10.3897/BDJ.8.e50775 | 32,210,673 | Biodiversity data journal | 2,020 | ||
Activin-A modulates gonadotropin-releasing hormone secretion from a gonadotropin-releasing hormone-secreting neuronal cell line. | The recent development of GnRH-secreting neuronal cell lines (GT1-1, GT1-3 and GT1-7 clones) has provided a model system for the study of the neural regulation of GnRH expression and secretion. We report here that activin-A stimulates GnRH secretion by GT1-7 cells in a dose-dependent manner, with an EC50 of approximate... | 10.1159/000125916 | 1,758,579 | D028341:Activins; D002460:Cell Line; D002999:Clone Cells; D007987:Gonadotropin-Releasing Hormone; D007265:Inhibins; D009474:Neurons; D011863:Radioimmunoassay; D012098:Reproduction; D016212:Transforming Growth Factor beta | Neuroendocrinology | 1,991 | D016212:Transforming Growth Factor beta; D028341:Activins; D007987:Gonadotropin-Releasing Hormone; D007265:Inhibins |
Photocatalytic CO2 Reduction Mediated by Electron Transfer via the Excited Triplet State of Zn(II) Porphyrin. | A porphyrin/rhenium complex dyad, ZnP-phen=Re, in which the 2-position of the 1,10-phenanthroline (phen) of fac-Re(phen)(CO)3Br is directly connected with the meso-position of zinc(II) porphyrin, showed phosphorescence from the zinc porphyrin part under Ar, even at room temperature. The phosphorescence was efficiently ... | 10.1021/jacs.9b12712 | 31,887,033 | Journal of the American Chemical Society | 2,020 | ||
Cerebral blood flow in sickle cell cerebrovascular disease. | Cerebral blood flow (CBF) has been studied by the xenon-133 (133Xe) inhalation method in 16 children with suspected sickle cell cerebrovascular disease. Abnormalities consisting of decreases in total, hemispheral, or regional CBF were found in 17 of 26 studies. Eleven studies performed immediately after stroke, transie... | 6,718,116 | D000293:Adolescent; D000755:Anemia, Sickle Cell; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders; D002648:Child; D002675:Child, Preschool; D003128:Coma; D005078:Exchange Transfusion, Whole Blood; D006801:Humans; D007223:Infant; D002546:Ischemic Attack, Transient; D011877:Radionuclide Imaging; D01... | Pediatrics | 1,984 | D014980:Xenon Radioisotopes | |
A novel, definitive test for substrate channeling illustrated with the aspartate aminotransferase/malate dehydrogenase system. | A novel method is presented that establishes definitively the existence or nonexistence of direct metabolite transfer between consecutive enzymes in a metabolic sequence. The procedure is developed with the specific example of channeling of oxaloacetate between Escherichia coli aspartate aminotransferase (AATase) and m... | 10.1021/bi983029c | 10,387,047 | D001120:Arginine; D001219:Aspartate Aminotransferases; D001224:Aspartic Acid; D004926:Escherichia coli; D008291:Malate Dehydrogenase; D008293:Malates; D009097:Multienzyme Complexes; D016297:Mutagenesis, Site-Directed; D062907:Oxaloacetic Acid; D011736:Pyridoxine; D013379:Substrate Specificity | Biochemistry | 1,999 | D008293:Malates; D009097:Multienzyme Complexes; D062907:Oxaloacetic Acid; D001224:Aspartic Acid; C030298:malic acid; D001120:Arginine; D008291:Malate Dehydrogenase; D001219:Aspartate Aminotransferases; D011736:Pyridoxine |
Mitral annulus distortion during beating heart surgery: a potential cause for hemodynamic disturbance--a three-dimensional echocardiography reconstruction study. | BACKGROUND
Positioning for access to the coronary arteries leads to hemodynamic instability during off-pump cardiac surgery. External changes have been well described, but a description of the intracardiac structures in humans has not been described.
METHODS
With multiplane intraoperative echocardiography, the mitral... | 10.1016/s0003-4975(02)03406-9 | 12,022,527 | D001794:Blood Pressure; D001026:Coronary Artery Bypass; D003971:Diastole; D019560:Echocardiography, Three-Dimensional; D006439:Hemodynamics; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007431:Intraoperative Complications; D019060:Minimally Invasive Surgical Procedures; D008943:Mitral Valve; D017202:My... | The Annals of thoracic surgery | 2,002 | |
Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trials. | The potential utility of tumor-infiltrating lymphocytes (TIL) in the adoptive immunotherapy of human tumors has been suggested by murine experiments showing these cells to be 50-100 times more powerful than LAK cells in treating advanced metastatic disease. A method for the large-scale expansion of human TIL for the us... | 10.1016/s0022-1759(87)80018-2 | 3,305,708 | D002478:Cells, Cultured; D002986:Clinical Trials as Topic; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007116:Immunization, Passive; D007167:Immunotherapy; D007376:Interleukin-2; D008214:Lymphocytes; D009369:Neoplasms; D010641:Phenotype | Journal of immunological methods | 1,987 | D007376:Interleukin-2 |
Pacemaker malfunction simulated by amplifier saturation. | In this case report, pacemaker malfunction is simulated by prolonged pauses after each pacemaker discharge. The pauses were due to saturation of the input of the telemetry monitor amplifier by the discharge voltage of the pacemaker. It is important to recognize amplifier saturation as a form of artifact that can mimic ... | 10.1111/j.1540-8159.1985.tb05889.x | 2,414,758 | D000368:Aged; D001145:Arrhythmias, Cardiac; D004562:Electrocardiography; D004582:Electronics, Medical; D005260:Female; D006801:Humans; D010138:Pacemaker, Artificial | Pacing and clinical electrophysiology : PACE | 1,985 | |
Diving and chronic spontaneous pneumothorax. | Diving and pneumothorax cannot go together. An air bubble between the visceral and the parietal pleura will change its size according to Boyle's law, and pneumothorax might increase in size during the ascent from a dive. We would like to present the case of a professional diver, who was engaged in active diving for a p... | 10.1378/chest.87.2.264 | 3,967,535 | D000328:Adult; D004242:Diving; D006801:Humans; D008297:Male; D011030:Pneumothorax | Chest | 1,985 | |
Metal-Organic Frameworks as Catalysts for Organic Synthesis: A Critical Perspective. | Recent advances in organic chemistry and materials chemistry have enabled the porosity of new materials to be accurately controlled on the nanometer scale. In this context, metal-organic frameworks (MOFs) have rapidly become one of the most attractive classes of solid supports currently under investigation in heterogen... | 10.1021/jacs.9b00733 | 30,974,060 | Journal of the American Chemical Society | 2,019 | ||
Home and expatriate nurses' perceptions of job satisfaction: Qualitative findings. | AIM
This paper is part of a larger doctoral study that investigated the impact of nationality on the job satisfaction of nurses and their intentions to leave Saudi Arabian government hospitals. The paper aims to gain an understanding of the impact of expatriate status on nurses' perceptions, by comparing the factors th... | 10.1111/inr.12699 | 34,043,818 | D003430:Cross-Sectional Studies; D006801:Humans; D007588:Job Satisfaction; D009726:Nurses; D009741:Nursing Staff, Hospital; D012529:Saudi Arabia; D011795:Surveys and Questionnaires | International nursing review | 2,022 | |
Rapid detection of herpes-simplex-virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis. | Herpes-simplex-virus (HSV) DNA in cerebrospinal fluid was amplified by use of the polymerase chain reaction and identified by hybridisation to a specific oligonucleotide probe. Specimens of cerebrospinal fluid (CSF) from 4 of 4 patients with herpes simplex encephalitis were positive for HSV DNA, whereas CSF specimens f... | 10.1016/0140-6736(90)90667-t | 1,968,171 | D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral; D004660:Encephalitis; D005069:Evaluation Studies as Topic; D005260:Female; D006561:Herpes Simplex; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D018139:Simplexvirus; D013997... | Lancet (London, England) | 1,990 | D004279:DNA, Viral |
Medical audit in general practice. II: Effects on health of patients with common childhood conditions. North of England Study of Standards and Performance in General Practice. | OBJECTIVE
To estimate the effects of medical audit, particularly setting clinical standards, on patients' health.
DESIGN
Before and after study strengthened by a replicated Latin square.
SETTING
62 training general practices in the north of England.
PATIENTS
Random sample of 9000 children with any of five conditi... | 10.1136/bmj.304.6840.1484 | 1,611,373 | D002648:Child; D002675:Child, Preschool; D002983:Clinical Competence; D004739:England; D005194:Family Practice; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008485:Medical Audit; D010290:Parents; D010349:Patient Compliance; D012008:Recurrence; D012135:Respiratory Sounds; D016896:Treatment Outcome | BMJ (Clinical research ed.) | 1,992 | |
C-reactive protein suppresses insulin signaling in endothelial cells: role of spleen tyrosine kinase. | Although few epidemiological studies have demonstrated that C-reactive protein (CRP) is related to insulin resistance, no study to date has examined the molecular mechanism. Here, we show that recombinant CRP attenuates insulin signaling through the regulation of spleen tyrosine kinase (Syk) on small G-protein RhoA, ju... | 10.1210/me.2006-0354 | 17,095,576 | D000818:Animals; D002097:C-Reactive Protein; D002417:Cattle; D002478:Cells, Cultured; D042783:Endothelial Cells; D019332:Endothelin-1; D004730:Endothelium, Vascular; D007328:Insulin; D055504:Insulin Receptor Substrate Proteins; D007333:Insulin Resistance; D047908:Intracellular Signaling Peptides and Proteins; D048670:M... | Molecular endocrinology (Baltimore, Md.) | 2,007 | D019332:Endothelin-1; D007328:Insulin; D055504:Insulin Receptor Substrate Proteins; D047908:Intracellular Signaling Peptides and Proteins; C526295:Irs1 protein, mouse; D010750:Phosphoproteins; D017452:Receptors, IgG; D011994:Recombinant Proteins; D013267:Stilbenes; D009569:Nitric Oxide; C041525:3,3',4,5'-tetrahydroxyst... |
Study on the Degradation of Optical Silicone Exposed to Harsh Environments. | Degradation mechanisms of silicone plates under harsh environment conditions are studied in this investigation. Environmental degradation of silicone free form, used as secondary optics in Light Emitting Diode LED lighting lamps and luminaires or any other applications requiring high quality optics being used, has nega... | 10.3390/ma11081305 | 30,060,563 | Materials (Basel, Switzerland) | 2,018 | ||
Posttraumatic growth in cancer: reality or illusion? | Research in posttraumatic growth (PTG) among cancer patients has been triggered primarily by the inclusion of serious illnesses among the events that can lead to posttraumatic stress disorder (PTSD); increasing survival rates among cancer patients; and, attempts at encouraging a positive psychology that focuses on a pa... | 10.1016/j.cpr.2008.09.006 | 18,996,633 | D001828:Body Image; D005817:Genetic Counseling; D006801:Humans; D008016:Life Change Events; D009369:Neoplasms; D012649:Self Concept; D012933:Social Identification; D013313:Stress Disorders, Post-Traumatic | Clinical psychology review | 2,009 | |
The usefulness of selected biomarkers in patients with valve disease. | AIM
The aim of the study was to investigate the prognostic value of selected biomarkers in patients undergoing valve surgery.
MATERIALS & METHODS
A prospective study was conducted on a group of consecutive patients with hemodynamically significant valve defects that underwent elective valve repair or replacement surg... | 10.2217/bmm-2018-0101 | 30,520,658 | D019540:Area Under Curve; D015415:Biomarkers; D004906:Erythrocyte Count; D005260:Female; D006349:Heart Valve Diseases; D006801:Humans; D008297:Male; D008875:Middle Aged | Biomarkers in medicine | 2,018 | D015415:Biomarkers |
Analysis of baculovirus IE1 in living cells: dynamics and spatial relationships to viral structural proteins. | IE1, a principal transcriptional activator of the baculovirus Bombyx mori nucleopolyhedrovirus (BmNPV), is an essential factor for viral DNA replication. During viral infection, IE1 accumulates in discrete subnuclear structures where viral DNA replication occurs. To analyse the dynamic properties of IE1, we monitored g... | 10.1099/vir.0.80418-0 | 15,557,230 | D000818:Animals; D012831:Bombyx; D036022:Capsid Proteins; D004261:DNA Replication; D004279:DNA, Viral; D004268:DNA-Binding Proteins; D017874:Immediate-Early Proteins; D017924:Nucleopolyhedroviruses; D015534:Trans-Activators; D015678:Viral Structural Proteins | The Journal of general virology | 2,004 | C069183:Ac-IE-1 protein, Autographa californica nucleopolyhedrovirus; D036022:Capsid Proteins; D004279:DNA, Viral; D004268:DNA-Binding Proteins; D017874:Immediate-Early Proteins; D015534:Trans-Activators; D015678:Viral Structural Proteins |
Effects of fish caudal fin sweep angle and kinematics on thrust production during low-speed thunniform swimming. | Scombrid fish lunate caudal fins are characterized by a wide range of sweep angles. Scombrid that have small sweep-angle caudal fins move at higher swimming speeds, suggesting that smaller angles produce more thrust. Furthermore, scombrids occasionally use high angles of attack (AoA) suggesting this also has some thrus... | 10.1242/bio.040626 | 31,320,378 | Biology open | 2,019 | ||
Structural network alterations in patients with nasopharyngeal carcinoma after radiotherapy: A 1-year longitudinal study. | This longitudinal study explored the changed patterns of structural brain network after radiotherapy (RT) in patients with nasopharyngeal carcinoma (NPC). Diffusion tensor imaging (DTI) data were gathered from 35 patients with NPC at four time points: before RT (baseline), 0∼3 (acute), 6 (early delayed), and 12 months ... | 10.3389/fnins.2022.1059320 | 36,466,177 | Frontiers in neuroscience | 2,022 | ||
Dental fear, regularity of dental attendance and subjective evaluation of dental erosion in women with eating disorders. | This questionnaire study, with a response rate of 53%, examined self-induced vomiting, erosions and dental attendance in women with eating disorders (EDs) as well as dental fear and its effect on attendance and communication with the dentist. A survey of 371 responding women with EDs, who were recruited from a self-hel... | 10.1111/j.1600-0722.2005.00227.x | 16,048,521 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000856:Anorexia Nervosa; D052018:Bulimia Nervosa; D015897:Comorbidity; D016854:Dental Anxiety; D003729:Dental Care; D003812:Dentist-Patient Relations; D005260:Female; D006801:Humans; D008875:Middle Aged; D009664:Norway; D010342:Patient Acce... | European journal of oral sciences | 2,005 | |
Benign breast tumours in an African population. | A detailed prospective clinical study of 238 women presenting with benign breast swellings in the South Eastern equatorial rainforest of Nigeria clearly shows that 94% of lesions were due to two disorders, fibroadenomas and bacterial infections, and that they affected mostly young women in the peak of their reproductiv... | 2,086,798 | D000232:Adenofibroma; D000293:Adolescent; D000328:Adult; D001943:Breast Neoplasms; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008413:Mastitis; D008875:Middle Aged; D009549:Nigeria; D011446:Prospective Studies; D014376:Tuberculosis | Journal of the Royal College of Surgeons of Edinburgh | 1,990 | ||
Importance of vacuum for breastmilk expression. | OBJECTIVE
To determine the effect of the strength of applied vacuum on the flow rate and yield of breastmilk using an electric breast pump.
STUDY DESIGN
Twenty-one breastfeeding mothers and two expressing mothers expressed their breastmilk for 15 minutes using an electric breast pump set at their own maximum comforta... | 10.1089/bfm.2007.0028 | 18,333,764 | D000328:Adult; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007774:Lactation; D008055:Lipids; D008893:Milk Ejection; D008895:Milk, Human; D013396:Suction; D013997:Time Factors; D014618:Vacuum | Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine | 2,008 | D008055:Lipids |
[Burdenko N.N. main military-and-clinical hospital in military-and-medical museum funds]. | Burdenko N.N. Main military-and-clinical hospital fund in Military-and-medical museum the Russian Federation's Ministry of defense amounts to over 300 units of keeping - written and material sources, photodocuments in connection with the first Russian state medical and educational organization's activity. | 16,808,387 | D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006772:Hospitals, Military; D006801:Humans; D008887:Military Medicine; D009144:Museums; D012426:Russia; D012425:Russia (Pre-1917); D014586:USSR | Voenno-meditsinskii zhurnal | 2,006 | ||
Reduction of disease activity and disability with high-dose cyclophosphamide in patients with aggressive multiple sclerosis. | OBJECTIVE
To explore the safety and effectiveness of high-dose cyclophosphamide (HiCy) without bone marrow transplantation in patients with aggressive multiple sclerosis (MS).
DESIGN
A 2-year open-label trial of patients with aggressive relapsing-remitting multiple sclerosis (RRMS) given an immunoablative regimen of ... | 10.1001/archneurol.65.8.noc80042 | 18,541,787 | D000328:Adult; D015331:Cohort Studies; D003520:Cyclophosphamide; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting; D016896:Treatment Outcome | Archives of neurology | 2,008 | D003520:Cyclophosphamide |
Denture-reversing technique for assessing the soft tissue dimensional changes according to artificial tooth position in completely edentulous patients. | A digital workflow to assess the soft tissue dimensional changes in completely edentulous patients is described. Diagnostic casts obtained at 2 time points and the complete denture were scanned by using a desktop scanner. The denture scan was inverted by using a metrology software program to obtain the soft tissue cont... | 10.1016/j.prosdent.2019.06.007 | 31,753,463 | D003824:Denture, Complete; D006801:Humans; D009066:Mouth, Edentulous; D012984:Software; D014093:Tooth, Artificial | The Journal of prosthetic dentistry | 2,020 | |
Murine superficial lymph node surgery. | In the field of immunology, to understand the progression of an immune response against a vaccine, an infection or a tumour, the response is often followed over time. Similarly, the study of lymphocyte homeostasis requires time course experiments. Performing these studies within the same mouse is ideal to reduce the ex... | 22,643,669 | D000818:Animals; D008197:Lymph Node Excision; D008198:Lymph Nodes; D008214:Lymphocytes; D051379:Mice; D023421:Models, Animal | Journal of visualized experiments : JoVE | 2,012 | ||
Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for cerebral vitamin B5 stores in local myelin homeostasis. | Vitamin B5 (d-pantothenic acid; pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA), through which it plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism. In the brain, acetyl-CoA is ... | 10.1016/j.bbrc.2019.11.052 | 31,759,626 | D000818:Animals; D001921:Brain; D001923:Brain Chemistry; D003921:Diabetes Mellitus, Experimental; D006816:Huntington Disease; D008297:Male; D009186:Myelin Sheath; D010205:Pantothenic Acid; D051381:Rats; D017208:Rats, Wistar | Biochemical and biophysical research communications | 2,020 | D010205:Pantothenic Acid |
Neutralizing feature of commercially available feline calicivirus (FCV) vaccine immune sera against FCV field isolates. | Four types of commercially available feline calicivirus (FCV) vaccine were compared in terms of their efficacy on the basis of the ability of the sera of specific-pathogen-free cats immunized by two injections of each type of vaccine to neutralize FCV field isolates. Each vaccine immune serum neutralized relatively wel... | 10.1292/jvms.61.299 | 10,331,208 | D000818:Animals; D017250:Caliciviridae Infections; D017927:Calicivirus, Feline; D002371:Cat Diseases; D002415:Cats; D007106:Immune Sera; D009500:Neutralization Tests; D014765:Viral Vaccines | The Journal of veterinary medical science | 1,999 | D007106:Immune Sera; D014765:Viral Vaccines |
Disappearance and reappearance of islet cell cytoplasmic antibodies in cyclosporin-treated insulin-dependent diabetics. | In 68 newly diagnosed patients with insulin-dependent diabetes mellitus (IDDM) whose treatment included cyclosporin (CyA) the prevalence and mean titre of islet cell cytoplasmic antibodies (ICA) fell faster than they did in the 56 who received only insulin. However, in the CyA-treated patients the prevalence or titre o... | 10.1016/s0140-6736(85)92143-9 | 2,857,945 | D000293:Adolescent; D000328:Adult; D001323:Autoantibodies; D002096:C-Peptide; D002648:Child; D003524:Cyclosporins; D003593:Cytoplasm; D003922:Diabetes Mellitus, Type 1; D005260:Female; D006801:Humans; D007515:Islets of Langerhans; D008297:Male; D013997:Time Factors | Lancet (London, England) | 1,985 | D001323:Autoantibodies; D002096:C-Peptide; D003524:Cyclosporins |
Nonoperative management of lower extremity claudication caused by a Baker's cyst: case report and review of the literature. | A Baker's or popliteal cyst is a synovial cyst in the popliteal fossa arising from the knee joint. The majority of patients develop a popliteal mass that is asymptomatic, but in a small percentage of patients, complications and symptoms occur; these may not only encompass the popliteal veins and arteries but may also i... | 10.1258/rsmvasc.13.4.244 | 16,229,799 | D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal; D003251:Constriction, Pathologic; D006801:Humans; D007383:Intermittent Claudication; D007719:Knee Joint; D008279:Magnetic Resonance Imaging; D008297:Male; D011151:Popliteal Cyst; D016896:Treatment Outcome | Vascular | 2,005 | D000894:Anti-Inflammatory Agents, Non-Steroidal |
Long-term follow-up of iatrogenic atrial septal defect: after percutaneous mitral balloon valvuloplasty. | During percutaneous mitral balloon valvuloplasty, the Inoue method leaves patients with an iatrogenic atrial septal defect. In this study, we evaluated the factors affecting the development of iatrogenic atrial septal defect and searched for the possible influence of this defect on long-term outcomes.We reviewed the me... | 22,163,126 | D000328:Adult; D054087:Atrial Septum; D002404:Catheterization; D016009:Chi-Square Distribution; D003287:Contrast Media; D018618:Echocardiography, Doppler, Color; D005260:Female; D006335:Heart Injuries; D006801:Humans; D007049:Iatrogenic Disease; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D008946:... | Texas Heart Institute journal | 2,011 | D003287:Contrast Media | |
Results obtained in the metrological certification of a commercially available radionuclide calibrator. | The paper presents the results obtained at IFIN-HH during a metrological certification of the commercially available radionuclide calibrator, the CURIEMENTOR2. Its performance was tested for the radionuclides: 57Co, 99mTc, 131I and 137Cs. The calibration factors determined by the manufacturer and those obtained at IFIN... | 10.1016/s0969-8043(01)00146-4 | 12,102,357 | D002138:Calibration; D011834:Radiation Monitoring; D011868:Radioisotopes; D015203:Reproducibility of Results | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine | 2,002 | D011868:Radioisotopes |
[The use of a respiratory regulator in the combined therapy of obstructive lung diseases]. | The authors review a method for the treatment of patients suffering from nonspecific pulmonary diseases associated with the obstructive syndrome by means of a respiratory regulator which permits the building of positive pressure of 2-4 cm H2O throughout expiration. External respiration, gas exchange and hemodynamics we... | 2,333,624 | D000403:Airway Resistance; D001249:Asthma; D001945:Breathing Exercises; D001991:Bronchitis; D002908:Chronic Disease; D003131:Combined Modality Therapy; D005069:Evaluation Studies as Topic; D006801:Humans; D008168:Lung; D008173:Lung Diseases, Obstructive; D012138:Respiratory Therapy | Terapevticheskii arkhiv | 1,990 | ||
Ultrasound-assisted lipoplasty: is It really safe? | During the last decade liposuction has become the most common aesthetic procedure. It has also become the most common aesthetic procedure performed by physicians not trained in plastic surgery. New developments such as the tumescent technique, finer cannulas, and, finally, the technique of ultrasound-assisted lipoplast... | 10.1007/s002669900290 | 10,541,842 | D000328:Adult; D000368:Aged; D006470:Hemorrhage; D006801:Humans; D015187:Lipectomy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012449:Safety; D018084:Ultrasonography, Interventional | Aesthetic plastic surgery | 1,999 | |
H-40, an antigen controlled by an Igh linked gene and recognized by cytotoxic T lymphocytes. I. Genetic analysis of H-40 and distribution of its product on B cell tumors. | C.B-20 ( Ighb ) mice challenged with BALB/c ( Igha ) spleen cells (or vice-versa) generate cytotoxic T lymphocytes (CTL) that recognize an antigen, H-40, controlled by an Igh-linked gene. The gene maps to the Igh-C region end of the Igh complex, telomeric to Tsu in the region of Pre-1. At least three alleles, a, b, and... | 10.1084/jem.159.6.1724 | 6,427,384 | D000483:Alleles; D000818:Animals; D001402:B-Lymphocytes; D005786:Gene Expression Regulation; D006183:H-2 Antigens; D006649:Histocompatibility Antigens; D006824:Hybridization, Genetic; D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region; D008223:Lymphoma; D051379:Mice; D008807:Mice, Inbred BALB C... | The Journal of experimental medicine | 1,984 | D006183:H-2 Antigens; D006649:Histocompatibility Antigens; D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region |
WITHDRAWN: Cardio-cerebrovascular protective effects of valsartan in high-risk hypertensive patients with overweight/obesity: A post-hoc analysis of the KYOTO HEART Study. | This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. | 10.1016/j.ijcard.2012.06.103 | 22,795,716 | International journal of cardiology | 2,012 | ||
[The problem-oriented case report--a method for the improvement of clinical training]. | Abroad in the clinical education of the students the problem-oriented case report after Weed stood the test as a new training principle. In contrast to the classical case report the complaints and findings are formulated as problems and summarized in a list of problems. As problem is regarded what needs a diagnostic or... | 6,969,006 | D004501:Education, Medical; D008487:Medical History Taking; D008499:Medical Records; D008501:Medical Records, Problem-Oriented | Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete | 1,980 |
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