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Medial patellofemoral ligament reconstruction fixed with a cylindrical bone plug and a grafted semitendinosus tendon at the original femoral site for recurrent patellar dislocation. | BACKGROUND
The medial patellofemoral ligament (MPFL) is the most important factor for stabilizing the patella and preventing lateral patellar dislocation. Medial patellofemoral ligament reconstruction is an accepted surgical technique to restore patellofemoral stability after lateral patellar dislocation. The authors r... | 10.1177/0363546510377436 | 20,929,934 | D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005269:Femur; D006801:Humans; D007593:Joint Instability; D008023:Ligaments, Articular; D008297:Male; D017888:Medial Collateral Ligament, Knee; D009984:Orthopedic Fixation Devices; D019637:Orthopedic Procedures; D031222:Patellar Dislocation; D057071:Pate... | The American journal of sports medicine | 2,011 | |
Balancing selection versus allele and supertype turnover in MHC class II genes in guppies. | Selection pressure from parasites is thought to be a major force shaping the extreme polymorphism of the major histocompatibility complex (MHC) genes, but the modes and consequences of selection remain unclear. Here, we analyse MHC class II and microsatellite diversity in 16 guppy (Poecilia reticulata) populations from... | 10.1038/s41437-020-00369-7 | 32,985,616 | D000483:Alleles; D000818:Animals; D005802:Genes, MHC Class II; D014644:Genetic Variation; D010802:Phylogeny; D011036:Poecilia; D012641:Selection, Genetic | Heredity | 2,021 | |
Density Functional Theory Study on the Enhancement Mechanism of the Photocatalytic Properties of the g-C3N4/BiOBr(001) Heterostructure. | The van der Waals heterostructures fabricated in two semiconductors are currently attracting considerable attention in various research fields. Our study uses density functional theory calculations within the Heyd-Scuseria-Ernzerhof hybrid functional to analyze the geometric structure and electronic structure of the g-... | 10.1021/acsomega.2c04298 | 36,278,081 | ACS omega | 2,022 | ||
Methylene Blue inhibits the inflammatory process of the acetic acid-induced colitis in the rat colonic mucosa. | Inflammatory bowel disease is a serious health problem. Although it has been widely investigated, treatment of inflammatory bowel diseases currently remains as a challenging clinical problem. Over production of nitric oxide has been demonstrated to cause tissue damage and inflammation. In this study, the effect of meth... | 10.9738/INTSURG-D-15-00118.1 | 26,062,761 | International surgery | 2,015 | ||
Blood vitamin C levels of motorized tricycle drivers in Parañaque, Philippines. | Vitamin C is an essential micronutrient maintaining the state of well being of individuals. This study examined factors affecting and the blood vitamin C levels of motorized tricycle drivers in Parañaque City, Philippines. Consenting drivers (N=49) were included in the study and were assessed through self-administered ... | 10.2486/indhealth.46.389 | 18,716,387 | D000328:Adult; D001205:Ascorbic Acid; D003430:Cross-Sectional Studies; D019587:Dietary Supplements; D006801:Humans; D008297:Male; D008875:Middle Aged; D018986:Motor Vehicles; D016272:Occupational Health; D010679:Philippines; D011795:Surveys and Questionnaires; D014186:Transportation; D017132:Workplace | Industrial health | 2,008 | D001205:Ascorbic Acid |
Single intradiscal injection of the interleukin-6 receptor antibody tocilizumab provides short-term relief of discogenic low back pain; prospective comparative cohort study. | BACKGROUND
Inflammatory cytokines, such as interleukin-6 and tumor necrosis factor-α, are gaining attention as important etiologic factors associated with discogenic low back pain. We conducted a prospective cohort study to evaluate the efficacy and safety of intradiscal injection of the interleukin-6 receptor antibody... | 26,755,382 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D061067:Antibodies, Monoclonal, Humanized; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D007403:Intervertebral Disc; D055959:Intervertebral Disc Degeneration; D017116:Low Back Pain; D008297:Male; D008875:Middle Aged; D... | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association | 2,016 | D061067:Antibodies, Monoclonal, Humanized; D019947:Receptors, Interleukin-6; C502936:tocilizumab | |
Preparation and performance of chitosan encapsulated activated charcoal (ACCB) adsorbents for small molecules. | A technique is described to encapsulate activated charcoal for haemoperfusion to be used in an artificial liver support. Activated charcoal was encapsulated within chitosan matrix (ACCB) in different concentrations, and was used as the supports for perfusion of a mixture of solutes, having molecular weight ranges from ... | 10.3109/02652049309015324 | 8,263,676 | D000327:Adsorption; D001663:Bilirubin; D001672:Biocompatible Materials; D002606:Charcoal; D002614:Chelating Agents; D002686:Chitin; D048271:Chitosan; D003404:Creatinine; D004339:Drug Compounding; D006461:Hemolysis; D006801:Humans; D007444:Inulin; D012709:Serum Albumin; D013816:Thermodynamics; D014118:Toxins, Biological... | Journal of microencapsulation | 1,993 | D001672:Biocompatible Materials; D002614:Chelating Agents; D012709:Serum Albumin; D014118:Toxins, Biological; D002686:Chitin; D002606:Charcoal; D014527:Uric Acid; D014508:Urea; D007444:Inulin; D048271:Chitosan; D003404:Creatinine; D001663:Bilirubin |
But doctor, it's my hip!: the fate of failed medical devices. | It is difficult to study failed medical devices because of a lack of data. Routine device retrieval and analysis (DRA) is essential to performance evaluation, which, in turn, is essential to good patient care. We argue for the development of a national DRA program and medical device database and discuss the major ethic... | 10.1353/ken.0.0094 | 10,172,331 | D003257:Consumer Product Safety; D016208:Databases, Factual; D030881:Disclosure; D004868:Equipment Failure; D004869:Equipment Safety; D004992:Ethics, Medical; D035082:Federal Government; D033161:Government Regulation; D006801:Humans; D011358:Product Surveillance, Postmarketing; D016730:Program Development; D019736:Pros... | Kennedy Institute of Ethics journal | 1,995 | |
Effect of extracellular electron shuttles on arsenic-mobilizing activities in soil microbial communities. | Microbially mediated arsenate (As(V)) and Fe(III) reduction play important roles in arsenic (As) cycling in nature. Extracellular electron shuttles can impact microbial Fe(III) reduction, yet little is known about their effects on microbial As mobilization in soils. In this study, microcosm experiments consisting of an... | 10.1016/j.jhazmat.2017.08.071 | 28,888,188 | D000880:Anthraquinones; D001149:Arsenates; D001151:Arsenic; D001419:Bacteria; D001673:Biodegradation, Environmental; D004583:Electrons; D005290:Ferric Compounds; D008903:Minerals; D012988:Soil Microbiology | Journal of hazardous materials | 2,018 | D000880:Anthraquinones; D001149:Arsenates; D005290:Ferric Compounds; D008903:Minerals; D001151:Arsenic; C025657:arsenic acid |
Effects of intermittent injections of LHRH on specific binding of 125I-labeled gonadotropins to granulosa and theca, and concentrations of steroids in serum and ovarian follicles during postpartum anovulation in suckled beef cows. | To examine ovarian follicular response to low-dose injections of luteinizing hormone-releasing hormone (LHRH), 32 anovulatory, suckled beef cows were allotted to one of four treatment groups and injected with either saline or 500 ng LHRH every 2 h for 48 or 96 h, starting 21.4 +/- .4 d after parturition. Two hours afte... | 10.2527/jas1986.6251324x | 3,522,520 | D000818:Animals; D000858:Anovulation; D001665:Binding Sites; D002417:Cattle; D006063:Chorionic Gonadotropin; D004958:Estradiol; D005260:Female; D007987:Gonadotropin-Releasing Hormone; D006107:Granulosa Cells; D007275:Injections, Intravenous; D006080:Ovarian Follicle; D010052:Ovariectomy; D011374:Progesterone; D013799:T... | Journal of animal science | 1,986 | D006063:Chorionic Gonadotropin; D007987:Gonadotropin-Releasing Hormone; D011374:Progesterone; D004958:Estradiol |
Synaptic-like microvesicles in mammalian pinealocytes. | The recent deciphering of the protein composition of the synaptic vesicle membrane has led to the unexpected identification of a compartment of electron-lucent microvesicles in neuroendocrine cells which resemble neuronal synaptic vesicles in terms of molecular structure and function. These vesicles are generally refer... | 10.1016/s0074-7696(08)60160-6 | 10,343,394 | D000818:Animals; D003624:Darkness; D007150:Immunohistochemistry; D008322:Mammals; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D019899:Paracrine Communication; D010870:Pineal Gland; D013572:Synaptic Vesicles | International review of cytology | 1,999 | D008565:Membrane Proteins; D009419:Nerve Tissue Proteins |
Inhibition of juvenile hormone esterase activity in Lymantria dispar (Lepidoptera, Lymantriidae) larvae parasitized by Glyptapanteles liparidis (Hymenoptera, Braconidae). | Glyptapanteles liparidis is a gregarious, polydnavirus (PDV)-carrying braconid wasp that parasitizes larval stages of Lymantria dispar. In previous studies we showed that parasitized hosts dramatically increase juvenile hormone (JH) titers, whereas JH degradation is significantly inhibited in the hemolymph. Here we (i)... | 10.1016/j.jinsphys.2007.05.010 | 17,631,309 | D000818:Animals; D002265:Carboxylic Ester Hydrolases; D015536:Down-Regulation; D005216:Fat Body; D006458:Hemolymph; D006790:Host-Parasite Interactions; D007814:Larva; D008675:Metamorphosis, Biological; D009036:Moths; D018071:Polydnaviridae; D013997:Time Factors; D014862:Wasp Venoms; D014863:Wasps | Journal of insect physiology | 2,007 | D014862:Wasp Venoms; D002265:Carboxylic Ester Hydrolases; C038003:juvenile hormone esterase |
Advanced glycation endproducts are deposited in neuronal hyaline inclusions: a study on familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation. | To determine the role of advanced glycation endproducts (AGE) in the pathogenesis of familial amyotrophic lateral sclerosis (ALS) with superoxide dismutase-1 (SOD1) mutation, we investigated the immunohistochemical localization of N(epsilon)-carboxymethyl-lysine (CML), one of the major AGE structures, in spinal cords f... | 10.1007/s004010050980 | 10,090,670 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000690:Amyotrophic Lateral Sclerosis; D000906:Antibodies; D005260:Female; D017127:Glycation End Products, Advanced; D006801:Humans; D006818:Hyalin; D007150:Immunohistochemistry; D002479:Inclusion Bodies; D008239:Lysine; D008297:Male; D016253:Microscopy, Immunoele... | Acta neuropathologica | 1,999 | D000906:Antibodies; D017127:Glycation End Products, Advanced; D016900:Neurofilament Proteins; C000606290:SOD1 protein, human; D014452:Ubiquitins; C048496:N(6)-carboxymethyllysine; D013482:Superoxide Dismutase; D000072105:Superoxide Dismutase-1; D008239:Lysine |
Comparative functional analysis of mice after local injection with botulinum neurotoxin A1, A2, A6, and B1 by catwalk analysis. | Botulinum neurotoxins (BoNTs) are potent neurotoxins and are the causative agent of botulism, as well as valuable pharmaceuticals. BoNTs are divided into seven serotypes that comprise over 40 reported subtypes. BoNT/A1 and BoNT/B1 are currently the only subtypes approved for pharmaceutical use in the USA. While several... | 10.1016/j.toxicon.2019.06.004 | 31,181,297 | D000818:Animals; D001681:Biological Assay; D001905:Botulinum Toxins; D003014:Clostridium botulinum; D005684:Gait; D051379:Mice; D010543:Peroneal Nerve; D012584:Sciatic Nerve; D013979:Tibial Nerve; D018675:Toxicity Tests | Toxicon : official journal of the International Society on Toxinology | 2,019 | D001905:Botulinum Toxins |
Serotypes of Nag Vibrios isolated from clinical and environmental sources. | Nag Vibrios isolated in two districts in Romania were typed with the 38 "O" Nag antisera prepared in our laboratory. Nag serotype O:5 was found to be prevalent. | 664,980 | D005243:Feces; D006801:Humans; D012383:Romania; D012703:Serotyping; D014733:Vibrio; D014735:Vibrio Infections; D014871:Water Microbiology | Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie | 1,978 | ||
Feeding reduced-protein diets to broilers subjected to hypobaric hypoxia is associated with the development of pulmonary hypertension syndrome. | 1. There are few studies on the effect of dietary protein content on pulmonary hypertension syndrome (PHS) in broiler chickens. Conflicting results from these studies prevent a clear conclusion on the effects of reduced-protein diets on development of the syndrome. 2. To obtain an understanding of the mechanisms involv... | 10.1080/00071668.2012.727082 | 23,281,761 | D000399:Air Pressure; D000531:Altitude; D000818:Animals; D002645:Chickens; D004032:Diet; D004044:Dietary Proteins; D006976:Hypertension, Pulmonary; D008297:Male; D010100:Oxygen; D011201:Poultry Diseases; D011897:Random Allocation | British poultry science | 2,012 | D004044:Dietary Proteins; D010100:Oxygen |
Origin and distribution of capsaicin-sensitive substance P-immunoreactive nerves in the nasal mucosa. | In immunohistochemical studies, substance P-immunoreactivity (SP-IR) was found in a population of trigeminal ganglion cells in guinea pig, rat and cat. SP-IR nerve endings were found in the spinal trigeminal nucleus, around sphenopalatine ganglion cells, around blood vessels, as well as under and within the epithelium ... | 10.3109/00016488309132735 | 6,195,888 | D000818:Animals; D002211:Capsaicin; D002415:Cats; D005260:Female; D005455:Fluorescent Antibody Technique; D005724:Ganglia; D005726:Ganglia, Parasympathetic; D005728:Ganglia, Sympathetic; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D009297:Nasal Mucosa; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred... | Acta oto-laryngologica | 1,983 | D013373:Substance P; D002211:Capsaicin |
Cataract surgery: limitations and barriers in Makurdi, Benue State. | BACKGROUND
Cataract is amenable to surgery; despite this affected patients do not always embrace or accept cataract surgical intervention. The study aims to ascertain the factors responsible for this negative attitude towards cataract surgery by affected patients.
METHODS
A prospective study was carried out with an i... | 10.4314/njm.v18i3.51166 | 20,120,639 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001766:Blindness; D002386:Cataract; D002387:Cataract Extraction; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006297:Health Services Accessibility; D006801:Humans; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D010342:Patient Acceptance o... | Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria | 2,009 | |
Severe tooth loss after root damage caused by predrilled intermaxillary fixation screw: a case report. | Intermaxillary fixation (IMF) with screws is routinely used as a conservative therapy or to obtain normal occlusion during the surgical procedure of open reduction and internal fixation for treating mandibular fractures. The risk of iatrogenic dental damage caused by interdental drilling is widely known. Several side e... | 10.1111/edt.12271 | 27,004,831 | D001863:Bone Screws; D005593:Fracture Fixation, Internal; D006801:Humans; D008297:Male; D008337:Mandibular Fractures; D016388:Tooth Loss; D014092:Tooth Root; D055815:Young Adult | Dental traumatology : official publication of International Association for Dental Traumatology | 2,016 | |
Dying in intensive care: An analysis of the perspectives of families and clinicians on end-of-life care. | BACKGROUND
Despite a growing body of research into end-of-life care (EOLC) in intensive care units (ICUs), few studies have concurrently explored the perspectives of families and clinicians.
OBJECTIVE
The objective of this study was to identify the characteristics of high-quality EOLC in the ICU from family and clini... | 10.1016/j.aucc.2022.07.004 | 36,089,461 | D000328:Adult; D006801:Humans; D013727:Terminal Care; D003422:Critical Care; D007362:Intensive Care Units; D011795:Surveys and Questionnaires; D017144:Focus Groups | Australian critical care : official journal of the Confederation of Australian Critical Care Nurses | 2,023 | |
Changes over time in survival of children after AIDS diagnosis in New York City. | We determined whether survival of children following AIDS diagnosis is improving over time through 1991. AIDS surveillance data from New York City Department of Health on 914 pediatric AIDS patients, diagnosed between 1979 and 1991 and presumed due to maternal-infant HIV transmission, were analyzed. Survival following ... | 7,669,359 | D000163:Acquired Immunodeficiency Syndrome; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009519:New York City; D016019:Survival Analysis; D015996:Survival Rate; D013997:Time Factors | American journal of preventive medicine | 1,995 | ||
Long-term sediment decline causes ongoing shrinkage of the Mekong megadelta, Vietnam. | Since the 1990s the Mekong River delta has suffered a large decline in sediment supply causing coastal erosion, following catchment disturbance through hydropower dam construction and sand extraction. However, our new geological reconstruction of 2500-years of delta shoreline changes show that serious coastal erosion a... | 10.1038/s41598-020-64630-z | 32,415,150 | Scientific reports | 2,020 | ||
Enriched Environment Reverts Somatostatin Interneuron Loss in MK-801 Model of Schizophrenia. | Dysregulation of the inhibitory drive has been proposed to be a central mechanism to explain symptoms and pathophysiological hallmarks in schizophrenia. A number of recent neuroanatomical studies suggest that certain types of inhibitory cells are deficient in schizophrenia, including somatostatin-immunoreactive interne... | 10.1007/s12035-019-01762-y | 31,506,899 | D000818:Animals; D016291:Dizocilpine Maleate; D006624:Hippocampus; D007395:Interneurons; D017397:Prefrontal Cortex; D020318:Rats, Long-Evans; D012559:Schizophrenia; D015398:Signal Transduction; D013004:Somatostatin | Molecular neurobiology | 2,020 | D013004:Somatostatin; D016291:Dizocilpine Maleate |
Refined imaging features of culprit plaques improve the prediction of recurrence in intracranial atherosclerotic stroke within the middle cerebral artery territory. | Recurrence is a significant adverse outcome of ischemic stroke (IS), particularly in cases of intracranial arteriosclerosis (ICAS). In this study, we investigated the impact of imaging features of culprit plaque using high-resolution magnetic resonance vessel wall imaging (HR-MR-VWI) on the prediction of IS recurrence.... | 10.1016/j.nicl.2023.103487 | 37,603,950 | D006801:Humans; D020768:Middle Cerebral Artery; D020521:Stroke; D000083242:Ischemic Stroke; D058225:Plaque, Amyloid; D002537:Intracranial Arteriosclerosis; D007238:Infarction | NeuroImage. Clinical | 2,023 | |
Validation of an automatic method for reconstruction, delineation, and measurement of levator hiatus in clinical practice. | OBJECTIVES
To evaluate the concordance between an automatic software program and manual evaluation in reconstructing, delineating, and measuring the levator hiatus (LH) on maximal Valsalva maneuver.
METHODS
This was a retrospective study analyzing archived raw ultrasound imaging data of 100 patients underwent transpe... | 10.1002/nau.25231 | 37,358,312 | D006801:Humans; D009119:Muscle Contraction; D017773:Pelvic Floor; D012189:Retrospective Studies; D021621:Imaging, Three-Dimensional; D014463:Ultrasonography; D014636:Valsalva Maneuver | Neurourology and urodynamics | 2,023 | |
[Dissemination of Patient Education in the Rehabilitation of Chronic Back Pain - Cost Analysis of a Program Implementation]. | The aim of the project is a cost analysis of 2 different strategies "train-the-trainer-seminar" (ttt-seminar) and "implementation guideline" (ig) in the implementation of a standardised patient education program in the inpatient rehabilitation of patients with chronic back pain. The implementation strategies were assig... | 10.1055/s-0042-123424 | 28,482,369 | D001416:Back Pain; D003365:Costs and Cost Analysis; D003479:Curriculum; D005858:Germany; D019983:Guideline Adherence; D006284:Health Plan Implementation; D006295:Health Resources; D006801:Humans; D033181:Information Dissemination; D009313:National Health Programs; D010348:Patient Care Team; D010353:Patient Education as... | Die Rehabilitation | 2,017 | |
[How should pregnant women be informed about drug toxicity? Report from the 43rd annual meeting of the Teratology Society--June 21-26. 2003--Philadelphia, USA]. | This report refers actual opinions of drug risk assessment and pregnancy labeling presented during the 43rd Annual Meeting of Teratology Society. The other congress topics are also reviewed. | 15,771,148 | D030881:Disclosure; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006266:Health Education; D006801:Humans; D011247:Pregnancy | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego | 2,004 | ||
Implementation of Web-Based Psychosocial Interventions for Adults With Acquired Brain Injury and Their Caregivers: Systematic Review. | BACKGROUND
More than 135 million people worldwide live with acquired brain injury (ABI) and its many psychosocial sequelae. This growing global burden necessitates scalable rehabilitation services. Despite demonstrated potential to increase the accessibility and scalability of psychosocial supports, digital health inte... | 10.2196/38100 | 35,881,432 | D000328:Adult; D006801:Humans; D001930:Brain Injuries; D017028:Caregivers; D020407:Internet; D000083626:Psychosocial Intervention | Journal of medical Internet research | 2,022 | |
Regulation of glycolysis in the pectoralis muscles of seasonally acclimatized American goldfinches exposed to cold. | Regulation of glycolysis was assessed in winter- and summer-acclimatized goldfinches (Carduelis tristis). We exposed birds to a thermo-neutral temperature (30 degrees C), moderate cold (-15 degrees C), and severe cold (0 degrees C in an atmosphere of 21% O2-79% He), and then measured concentrations of glycogen, glycoly... | 10.1152/ajpregu.1990.258.3.R711 | 2,316,716 | D000064:Acclimatization; D000818:Animals; D001717:Birds; D003080:Cold Temperature; D005636:Fructosephosphates; D019298:Glucose-6-Phosphate; D005958:Glucosephosphates; D006003:Glycogen; D006019:Glycolysis; D007035:Hypothermia; D010101:Oxygen Consumption; D010369:Pectoralis Muscles; D012621:Seasons | The American journal of physiology | 1,990 | D005636:Fructosephosphates; D005958:Glucosephosphates; D019298:Glucose-6-Phosphate; C027618:fructose-6-phosphate; D006003:Glycogen |
Balance rehabilitation for postural control in children with Autism Spectrum Disorder: A two-case report study. | OBJECTIVE
This study aimed to investigate the effect of balance rehabilitation on postural control in both low and increased cognitive load conditions in two children with Autism Spectrum Disorders (ASD).
METHODS
Two children diagnosed with ASD participated in a 4-week personalized balance rehabilitation program with... | 10.1080/09593985.2021.2017090 | 34,939,886 | D006801:Humans; D002648:Child; D000067877:Autism Spectrum Disorder; D004856:Postural Balance; D005239:Fear | Physiotherapy theory and practice | 2,023 | |
Palliative Care in Heart Failure: An Integrative Review of Nurse Practice. | Introduction: Because it is a chronic disease of progressive evolution, heart failure requires nursing attitudes and practices that are articulated with palliative care, implemented in an interdisciplinary team along with patients and their families. Objective: Identifying nurses' attitudes and practices in palliative ... | 10.1177/10499091221085276 | 35,414,263 | D006801:Humans; D010166:Palliative Care; D064946:Hospice and Palliative Care Nursing; D005190:Family; D006333:Heart Failure; D009726:Nurses | The American journal of hospice & palliative care | 2,023 | |
A Research on Online Education Behavior and Strategy in University. | After the reform and opening up in China, through a series of rapid developments in world, online education has grown both socially and economically. This area has become representative of the fast-growing economy. However, Guangfu culture as a crucial component of Cantonese traditional culture is gradually becoming le... | 10.3389/fpsyg.2022.767925 | 35,548,488 | Frontiers in psychology | 2,022 | ||
[The rich diversity of Whipple's disease]. | Whipple's disease (WD) is a rare, chronic multiorgan disease which can caused by Tropheryma whipplei, a ubiquitous gram positive bacterium. Detection of T. whipplei is mostly performed histologically using periodic acid-Schiff (PAS) staining in affected tissues to visualize characteristic PAS-positive macrophages and b... | 10.1007/s00393-018-0573-8 | 30,552,512 | D000328:Adult; D000900:Anti-Bacterial Agents; D003937:Diagnosis, Differential; D006801:Humans; D016133:Polymerase Chain Reaction; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D054851:Tropheryma; D008061:Whipple Disease | Zeitschrift fur Rheumatologie | 2,019 | D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination |
Pressure-induced phase transitions of lipid bilayers observed by fluorescent probes Prodan and Laurdan. | The fluorescence spectra of 6-propionyl-2-(dimethylamino)naphthalene (Prodan) and 6-dodecanoyl-2-(dimethylamino)naphthalene (Laurdan) in bilayer membranes of 1,2-distearoylphosphatidylcholine (DSPC) were observed as a function of pressure at constant temperature. The emission spectra of Prodan and Laurdan varied with t... | 10.1016/j.bpc.2005.05.007 | 15,961,215 | D015081:2-Naphthylamine; D005456:Fluorescent Dyes; D007848:Laurates; D008051:Lipid Bilayers; D015394:Molecular Structure; D044367:Phase Transition; D010713:Phosphatidylcholines; D011312:Pressure | Biophysical chemistry | 2,005 | D005456:Fluorescent Dyes; D007848:Laurates; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; C038517:prodan; D015081:2-Naphthylamine; C010942:1,2-distearoyllecithin; C065580:laurdan |
Investigation of the fabrication mechanism of self-assembled GaAs quantum rings grown by droplet epitaxy. | We have directly imaged the formation of a GaAs quantum ring (QR) using droplet epitaxy followed by annealing in arsenic ambient. Based on the atomic force micrograph measurement and the analysis of surface energy, we determine that the formation of self-assembled GaAs QRs is due to the gallium atom's diffusion and cry... | 10.1088/0957-4484/19/36/365604 | 21,828,875 | Nanotechnology | 2,008 | ||
Prediction of individual outcomes for asthma sufferers. | We consider the problem of individual-specific medication level recommendation (initiation, removal, increase, or decrease) for asthma sufferers. Asthma is one of the most common chronic diseases in both adults and children, affecting 8% of the US population and costing $37-63 billion/year in the United States of Ameri... | 10.1093/biostatistics/kxx055 | 29,121,247 | D001249:Asthma; D015331:Cohort Studies; D003198:Computer Simulation; D064420:Drug-Related Side Effects and Adverse Reactions; D019538:Health Care Surveys; D006801:Humans; D015233:Models, Statistical; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D014481:United States | Biostatistics (Oxford, England) | 2,018 | |
Reversal of loss of glomerular filtration rate in children with transplant nephropathy after switch to everolimus and low-dose cyclosporine A. | Until now there have been no good therapeutic options in children with biopsy-proven transplant nephropathy (TN) and loss of glomerular filtration rate (GFR) while receiving cyclosporine A (CsA), mycophenolate mofetil (MMF) and prednisolone (Pred). In 13 kidney transplanted children (mean age 13 yr, SD 4) with CsA/MMF/... | 10.1111/j.1399-3046.2006.00651.x | 17,430,485 | D000293:Adolescent; D001706:Biopsy; D002648:Child; D016572:Cyclosporine; D004359:Drug Therapy, Combination; D000068338:Everolimus; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007166:Immunosuppressive Agents; D007674:Kidney Diseases; D016030:Kidney Transplantation; D008297:Male; D020123:Sirolimu... | Pediatric transplantation | 2,007 | D007166:Immunosuppressive Agents; D016572:Cyclosporine; D000068338:Everolimus; D020123:Sirolimus |
Sesquiterpene lactones from Mikania micrantha and Mikania cordifolia and their cytotoxic and anti-inflammatory evaluation. | The guaianolide 8-epi-mikanokryptin (1) and the melampolide 11Hβ-11,13-dihydromicrantholide (2) along with known sesquiterpene lactones (3-13) and other constituents were isolated from the aerial parts of different populations of Mikania micrantha and Mikania cordifolia collected in several states of Mexico. The relati... | 24,565,963 | D000818:Animals; D000893:Anti-Inflammatory Agents; D045744:Cell Line, Tumor; D002470:Cell Survival; D018360:Crystallography, X-Ray; D004195:Disease Models, Animal; D004487:Edema; D006801:Humans; D020128:Inhibitory Concentration 50; D007783:Lactones; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D035742:Mikania... | Fitoterapia | 2,014 | C000594075:11Hbeta-11,13-dihydromicrantholide; C000594072:8-epi-mikanokryptin; D000893:Anti-Inflammatory Agents; D007783:Lactones; D010936:Plant Extracts; D012717:Sesquiterpenes; D045789:Sesquiterpenes, Guaiane | |
Carboxylated nanocellulose/poly(ethylene oxide) composite films as solid-solid phase-change materials for thermal energy storage. | Composite films of poly(ethylene oxide) (PEO) and 0%-20% surface-carboxylated cellulose nanofibrils (CNFs) were prepared by mixing the aqueous CNF dispersion and aqueous PEO solution at various weight ratios followed by casting and drying. The 20% CNF/PEO composite film was transparent, whereas the 100% PEO film was tr... | 10.1016/j.carbpol.2019.115215 | 31,521,315 | Carbohydrate polymers | 2,019 | ||
Modulation of the biosynthesis of some phenolic compounds in Olea europaea L. fruits: their influence on olive oil quality. | The phenolic composition of olive fruits (Olea europaea L.) (cv. Picual, Villalonga, Alfafarenca, and Cornicabra) grown in different areas of Spain was studied by high performance liquid chromatography-mass spectrometry. Different levels of tyrosol, catechin, p-coumaric acid, rutin, luteolin, and oleuropein were observ... | 10.1021/jf9913108 | 11,305,254 | D000975:Antioxidants; D002392:Catechin; D002851:Chromatography, High Pressure Liquid; D003373:Coumaric Acids; D005419:Flavonoids; D005638:Fruit; D057888:Iridoid Glucosides; D039823:Iridoids; D047311:Luteolin; D000069463:Olive Oil; D010636:Phenols; D010626:Phenylethyl Alcohol; D010938:Plant Oils; D011422:Propionates; D0... | Journal of agricultural and food chemistry | 2,001 | D000975:Antioxidants; D003373:Coumaric Acids; D005419:Flavonoids; D057888:Iridoid Glucosides; D039823:Iridoids; D000069463:Olive Oil; D010636:Phenols; D010938:Plant Oils; D011422:Propionates; D011714:Pyrans; C011867:4-hydroxyphenylethanol; C002769:oleuropein; D012431:Rutin; D002392:Catechin; C495469:p-coumaric acid; D0... |
The effect of cicletanine on cerebrovascular injury in stroke-prone spontaneously hypertensive rats. | The stroke-prone spontaneously hypertensive rat (SHR-SP) is one of the most suitable models for stroke study. The present trial work was undertaken so as to obtain further information concerning the action of a new furopyridine, cicletanine. Forty-six males--SHR-SP/Iffa Credo rats--aged 7 weeks, were divided into three... | 10.1093/ajh/2.9.683 | 2,803,675 | D000818:Animals; D000889:Anti-Arrhythmia Agents; D001522:Behavior, Animal; D001921:Brain; D002561:Cerebrovascular Disorders; D004232:Diuretics; D006973:Hypertension; D008297:Male; D008578:Meninges; D011725:Pyridines; D051381:Rats; D011919:Rats, Inbred Strains | American journal of hypertension | 1,989 | D000889:Anti-Arrhythmia Agents; D004232:Diuretics; D011725:Pyridines; C038068:cicletanine |
Evaluation of a Heart Transplant Candidate. | PURPOSE OF REVIEW
Heart transplantation is the best option for irreversible and critically advanced heart failure. However, limited donor pool, the risk of rejection, infection, and right ventricular dysfunction in short-term post-transplant period, as well as, the development of coronary allograft vasculopathy and mal... | 10.1007/s11886-017-0934-y | 29,103,157 | D015897:Comorbidity; D006333:Heart Failure; D016027:Heart Transplantation; D006801:Humans; D018579:Patient Selection; D011379:Prognosis; D012017:Referral and Consultation; D012307:Risk Factors; D012720:Severity of Illness Index; D014019:Tissue Donors | Current cardiology reports | 2,017 | |
MicroRNA fingerprints in serum and whole blood of sarcoid-affected horses as potential non-invasive diagnostic biomarkers. | Serum and whole blood microRNA (miRNA) fingerprints have been proposed as a new class of non-invasive human cancer biomarkers. In this study, we compared equine sarcoid (ES) disease-specific serum and whole blood miRNA fingerprints and correlated them to miRNA expression in sarcoid tissue. After high throughput sequenc... | 10.1111/vco.12451 | 30,430,738 | D000818:Animals; D014408:Biomarkers, Tumor; D015331:Cohort Studies; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006734:Horse Diseases; D006736:Horses; D008297:Male; D035683:MicroRNAs; D012878:Skin Neoplasms | Veterinary and comparative oncology | 2,019 | D014408:Biomarkers, Tumor; D035683:MicroRNAs |
Expression of neurofilaments in a neoplastic human salivary intercalated duct cell line or its derivatives and effect of nerve growth factor on the cellular proliferation and phenotype. | A neoplastic salivary cell line with an ultrastructure similar to that of an intercalated duct cell of the salivary gland, established from a human submandibular salivary gland, has been used in our laboratory as a model for studying mechanisms regulating cytodifferentiation in salivary glands. The expression of neurof... | 2,684,396 | D015415:Biomarkers; D015153:Blotting, Western; D002454:Cell Differentiation; D002455:Cell Division; D002460:Cell Line; D003599:Cytoskeleton; D005455:Fluorescent Antibody Technique; D006801:Humans; D007382:Intermediate Filaments; D008854:Microscopy, Electron; D009414:Nerve Growth Factors; D012468:Salivary Gland Neoplasm... | Cancer research | 1,989 | D015415:Biomarkers; D009414:Nerve Growth Factors | |
Two Novel Short Peptidoglycan Recognition Proteins (PGRPs) From the Deep Sea Vesicomyidae Clam Archivesica packardana: Identification, Recombinant Expression and Bioactivity. | Vesicomyidae clams are common species living in cold seeps, which incorporates symbiotic bacteria into their body maintaining endosymbiosis relationship. As members of pattern recognition receptor (PRR) family, peptidoglycan recognition proteins (PGRPs) recognize pathogen associated molecular patterns and play an impor... | 10.3389/fphys.2018.01476 | 30,405,434 | Frontiers in physiology | 2,018 | ||
Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate. | Fumaric acid esters are used to treat psoriasis, an inflammatory skin disease characterized by keratinocyte proliferation. Inflammation and proliferation are hallmarks of retinal disease; hence, fumaric acid esters may have therapeutic value in retinal pathology. In diseased retinas, Müller glial cells (MCs) undergo re... | 10.1002/glia.22266 | 22,072,423 | D000704:Analysis of Variance; D000818:Animals; D000831:Animals, Newborn; D014150:Antipsychotic Agents; D003879:Dermatologic Agents; D004305:Dose-Response Relationship, Drug; D058975:Folate Receptor 1; D005650:Fumarates; D005786:Gene Expression Regulation; D008298:Maleates; D051379:Mice; D008810:Mice, Inbred C57BL; D009... | Glia | 2,012 | D014150:Antipsychotic Agents; D003879:Dermatologic Agents; D058975:Folate Receptor 1; D005650:Fumarates; C473652:Hcar2 protein, mouse; D008298:Maleates; D058979:Proton-Coupled Folate Transporter; D012333:RNA, Messenger; D043562:Receptors, G-Protein-Coupled; D011978:Receptors, Nicotinic; D014665:Vasodilator Agents; C073... |
Patent Review on Laser Interference Lithography Technique for Producing Periodic Nanostructure. | BACKGROUND
Because line width has been close to atom size, for semiconductor industry, except for achieving the target of line width, the cost will be more important. The mask-less laser interference lithography (LIL) technique lowers the cost makes it standing out in the market of lithographic equipment of the excessi... | 10.2174/1872210512666180806141624 | 30,081,794 | Recent patents on nanotechnology | 2,018 | ||
[The enthesis. Physiological morphology, molecular composition and pathoanatomical alterations]. | The composition of the extracellular matrix in tendons and ligaments is directly related to the mechanical environment. Local compression triggers functional adaptation that leads to cartilage-specific transformation of the tissue. The molecular composition of the extracellular matrix at the enthesis is related to the ... | 10.1007/s00132-005-0807-8 | 15,909,175 | D000818:Animals; D001172:Arthritis, Rheumatoid; D019245:Compressive Strength; D005109:Extracellular Matrix; D016326:Extracellular Matrix Proteins; D006801:Humans; D008022:Ligaments; D040542:Mechanotransduction, Cellular; D013710:Tendons | Der Orthopade | 2,005 | D016326:Extracellular Matrix Proteins |
Role of Reversible Phase Transformation for Strong Piezoelectric Performance at the Morphotropic Phase Boundary. | A functional material with coexisting energetically equivalent phases often exhibits extraordinary properties such as piezoelectricity, ferromagnetism, and ferroelasticity, which is simultaneously accompanied by field-driven reversible phase transformation. The study on the interplay between such phase transformation a... | 10.1103/PhysRevLett.120.055501 | 29,481,186 | Physical review letters | 2,018 | ||
Expression and characterization of flagella in nonmotile enteroinvasive Escherichia coli isolated from diarrhea cases. | We report that enteroinvasive Escherichia coli (EIEC) serotypes considered to be nonmotile produce an unusually large (77 kDa) flagellin that is assembled into functional flagellum filaments that allow the bacteria to swim in modified motility agar. The EIEC flagellin showed N-terminal identity to most common enterobac... | 10.1128/IAI.70.10.5882-5886.2002 | 12,228,323 | D000595:Amino Acid Sequence; D001483:Base Sequence; D003429:Cross Reactions; D004269:DNA, Bacterial; D003967:Diarrhea; D004755:Enterobacteriaceae; D004926:Escherichia coli; D004927:Escherichia coli Infections; D005407:Flagella; D005408:Flagellin; D005798:Genes, Bacterial; D006801:Humans; D008969:Molecular Sequence Data... | Infection and immunity | 2,002 | D004269:DNA, Bacterial; D005408:Flagellin |
Endograft collapse after thoracic stent-graft repair for traumatic rupture. | Endovascular stent grafting has emerged as a new strategy for repair of traumatic aortic disruptions; however, this technique is not without complications. In this report, we describe a case of endograft collapse after a traumatic aortic rupture. | 10.1016/j.athoracsur.2008.09.012 | 19,379,911 | D000063:Accidents, Traffic; D000328:Adult; D001013:Aorta, Thoracic; D017545:Aortic Aneurysm, Thoracic; D001019:Aortic Rupture; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation; D006801:Humans; D011474:Prosthesis Design; D011475:Prosthesis Failure; D011859:Radiography; D015607:Stents; D01689... | The Annals of thoracic surgery | 2,009 | |
A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic. | Nosocomial infections with the Gram-positive pathogen Clostridium difficile pose a major risk for hospitalized patients and result in significant costs to health care systems. Here, we present the chemical synthesis of a PS-II hapten of a cell wall polysaccharide of hypervirulent ribotype 027 of C. difficile. Mice were... | 10.1016/j.chembiol.2011.03.009 | 21,609,839 | D000818:Animals; D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D001428:Bacterial Vaccines; D016360:Clostridioides difficile; D005260:Female; D006801:Humans; D007070:Immunoglobulin A; D051379:Mice; D008810:Mice, Inbred C57BL; D046228:Microarray Analysis; D009844:Oligosaccharides; D018074:Vaccines, Conjugate | Chemistry & biology | 2,011 | D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D001428:Bacterial Vaccines; D007070:Immunoglobulin A; D009844:Oligosaccharides; D018074:Vaccines, Conjugate; C028581:CRM197 (non-toxic variant of diphtheria toxin) |
Maps in the brain: what can we learn from them? | In mammalian visual cortex, neurons are organized according to their functional properties into multiple maps such as retinotopic, ocular dominance, orientation preference, direction of motion, and others. What determines the organization of cortical maps? We argue that cortical maps reflect neuronal connectivity in in... | 10.1146/annurev.neuro.27.070203.144226 | 15,217,337 | D000818:Animals; D001369:Axons; D001931:Brain Mapping; D003712:Dendrites; D006801:Humans; D009415:Nerve Net; D009434:Neural Pathways; D014793:Visual Cortex; D014794:Visual Fields; D014795:Visual Pathways | Annual review of neuroscience | 2,004 | |
[Industry of traditional Chinese patent medicine science and technology development and review]. | "Fifteen" since, our country Chinese traditional medicine industry science and technology has made remarkable achievements. In this paper, the development of science and technology policy, Chinese medicine industry, platform construction and other aspects were analyzed, showing 10 years of Chinese traditional medicine ... | 22,741,452 | D002681:China; D004365:Drugs, Chinese Herbal; D049674:History, 21st Century; D006801:Humans; D010330:Patents as Topic; D013678:Technology, Pharmaceutical | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | 2,012 | D004365:Drugs, Chinese Herbal | |
Plant extracts of the family Lauraceae: a potential resource for chemopreventive agents that activate the nuclear factor-erythroid 2-related factor 2/antioxidant response element pathway. | Cells and tissues counteract insults from exogenous or endogenous carcinogens through the expression of genes encoding antioxidants and phase II detoxifying enzymes regulated by antioxidant response element promoter regions. Nuclear factor-erythroid 2-related factor 2 plays a key role in regulating the antioxidant resp... | 10.1055/s-0034-1368197 | 24,585,092 | D016588:Anticarcinogenic Agents; D000975:Antioxidants; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D019770:Lauraceae; D050984:NF-E2 Transcription Factor, p45 Subunit; D010936:Plant Extracts | Planta medica | 2,014 | D016588:Anticarcinogenic Agents; D000975:Antioxidants; D050984:NF-E2 Transcription Factor, p45 Subunit; C494692:NFE2 protein, human; D010936:Plant Extracts |
Formation of Germa-ketenimine on the Ge(100) Surface by Adsorption of tert-Butyl Isocyanide. | Reactions of the (100) surfaces of Ge and Si with organic molecules have been generally understood within the concept of "dimers" formed by the 2 × 1 surface reconstruction. In this work, the adsorption of tert-butyl isocyanide on the Ge(100)-2 × 1 surface at large exposures is investigated under ultrahigh vacuum condi... | 10.1021/jacs.7b04755 | 28,560,877 | Journal of the American Chemical Society | 2,017 | ||
Subacute sclerosing panencephalitis: incidence among ethic groups in Israel. | During the period 1968-73, 46 patients with subacute sclerosing panencephalitis (SSPE), a fatal childhood disease related to rubeola, were encountered in Israel. The incidence per million population was 3.4 for Sephardic Jews, 3.2 for Arabs and only 0.5 for Ashkenazic Jews. An environmental factor which sharply demarca... | 1,116,935 | D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005006:Ethnicity; D005260:Female; D006680:HLA Antigens; D006801:Humans; D007557:Israel; D007585:Jews; D008297:Male; D012424:Rural Population; D013344:Subacute Sclerosing Panencephalitis | Israel journal of medical sciences | 1,975 | D006680:HLA Antigens | |
Chromosomal localization and molecular characterization of three different 5S ribosomal DNA clusters in the sea urchin Paracentrotus lividus. | In this paper the chromosomal localization and molecular cloning and characterization of three 5S rDNA clusters of 700 bp (base pairs), 900 bp, and 950 bp in the sea urchin Paracentrotus lividus are reported. Southern blot hybridization demonstrated the existence of three 5S rDNA repeats of differing length in the P. l... | 10.1139/g07-062 | 17,893,727 | D000818:Animals; D002874:Chromosome Mapping; D002875:Chromosomes; D003001:Cloning, Molecular; D004275:DNA, Ribosomal; D017404:In Situ Hybridization, Fluorescence; D047328:Paracentrotus; D012341:RNA, Ribosomal, 5S | Genome | 2,007 | D004275:DNA, Ribosomal; D012341:RNA, Ribosomal, 5S |
Group V secretory phospholipase A2 reveals its role in house dust mite-induced allergic pulmonary inflammation by regulation of dendritic cell function. | We have previously shown that group V secretory phospholipase A(2) (sPLA(2)) regulates phagocytosis of zymosan and Candida albicans by a mechanism that depends on fusion of phagosomes with late endosomes in macrophages. In this study, we report that group V sPLA(2) (Pla2g5)-null mice exposed to an extract of house dust... | 10.4049/jimmunol.1001384 | 20,817,863 | D000818:Animals; D017951:Antigen Presentation; D003713:Dendritic Cells; D054505:Group V Phospholipases A2; D006967:Hypersensitivity; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D054497:Phospholipases A2, Secretory; D011014:Pneumonia; D039981:Pyroglyphidae; D020133:Reverse Transcriptase Polymerase ... | Journal of immunology (Baltimore, Md. : 1950) | 2,010 | D054505:Group V Phospholipases A2; D054497:Phospholipases A2, Secretory; C516300:Pla2g5 protein, mouse |
Enzymatic degradation of Antheraea pernyi silk fibroin 3D scaffolds and fibers. | In this study, the in vitro enzymatic degradation behavior of the regenerated Antheraea pernyi silk fibroin (Ap-SF) three-dimensional (3D) scaffolds and the natural Ap-SF fibers exposed to enzyme solutions of α-chymotrypsin, collagenase IA and protease XIV were investigated. The results indicated that all three proteas... | 10.1016/j.ijbiomac.2010.11.004 | 21,087,623 | D000596:Amino Acids; D000818:Animals; D002417:Cattle; D002850:Chromatography, Gel; D002918:Chymotrypsin; D017364:Collagenases; D004798:Enzymes; D005349:Fibroins; D009036:Moths; D011402:Pronase; D011487:Protein Conformation; D017550:Spectroscopy, Fourier Transform Infrared | International journal of biological macromolecules | 2,011 | D000596:Amino Acids; D004798:Enzymes; D005349:Fibroins; D002918:Chymotrypsin; C117608:alpha-chymotrypsin; D017364:Collagenases; D011402:Pronase; C417249:collagenase 1 |
The importance of subclonal genetic events in MDS. | In this issue of Blood, Papaemmanuil et al present results from the largest single targeted sequencing effort in myelodysplastic syndrome (MDS) to date both in terms of number of patients studied (738 patients, of which 603 had MDS) and genes sequenced (111 genes). | 10.1182/blood-2013-09-527655 | 24,263,953 | D005260:Female; D006801:Humans; D008297:Male; D009154:Mutation; D009190:Myelodysplastic Syndromes | Blood | 2,013 | |
The potential of MRI-guided online adaptive re-optimisation in radiotherapy of urinary bladder cancer. | BACKGROUND AND PURPOSE
Adaptive radiotherapy (ART) using plan selection is being introduced clinically for bladder cancer, but the challenge of how to compensate for intra-fractional motion remains. The purpose of this study was to assess target coverage with respect to intra-fractional motion and the potential for nor... | 26,631,646 | D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011880:Radiotherapy Planning, Computer-Assisted; D061089:Radiotherapy, Image-Guided; D001749:Urinary Bladder Neoplasms | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology | 2,016 | ||
Pseudomonas aeruginosa lasA gene: determination of the transcription start point and analysis of the promoter/regulatory region. | The elastolytic activity of the opportunistic pathogen Pseudomonas aeruginosa is due to the combined activities of at least three secreted proteins: elastase, LasA and alkaline protease. Transcription of both the lasA gene and the elastase structural gene, lasB, requires the transcriptional activator LasR. In order to ... | 10.1016/0378-1119(93)90705-8 | 8,335,250 | D001426:Bacterial Proteins; D001483:Base Sequence; D015964:Gene Expression Regulation, Bacterial; D008666:Metalloendopeptidases; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides; D011401:Promoter Regions, Genetic; D011550:Pseudomonas aeruginosa; D012333:RNA, Messenge... | Gene | 1,993 | D001426:Bacterial Proteins; D009838:Oligodeoxyribonucleotides; D012333:RNA, Messenger; D008666:Metalloendopeptidases; C066371:staphylolytic protease |
Pneumothorax: a review of 146 adult cases admitted at a university teaching hospital in Pakistan. | OBJECTIVE
There is a lack of data on the etiology and outcome of pneumothorax among the Pakistani population. Our aim was to review the etiology, clinical course, management and outcome of patients presenting with pneumothorax.
PATIENTS AND METHODS
All adult cases with pneumothorax admitted to a University Teaching H... | 10,647,229 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive; D008297:Male; D008875:Middle Aged; D010154:Pakistan; D011030:Pneumothorax; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary | JPMA. The Journal of the Pakistan Medical Association | 1,999 | ||
Automated chip-based nanoelectrospray-mass spectrometry for rapid identification of proteins separated by two-dimensional gel electrophoresis. | We report a method using a fully automated chip-based nanoelectrospray system for two-dimensional (2-D) gel sample analyses with mass spectrometric detection. The automated nanoelectrospray system, consisting of the NanoMate and electrospray ionization (ESI) chip, serves as both an autosampler and nanoESI source. This ... | 10.1002/elps.200305585 | 14,613,186 | D000818:Animals; D002417:Cattle; D004396:Coloring Agents; D015180:Electrophoresis, Gel, Two-Dimensional; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli; D009211:Myoglobin; D011506:Proteins; D012709:Serum Albumin; D012710:Serum Albumin, Bovine; D021241:Spectrometry, Mass, Electrospray Ionization | Electrophoresis | 2,003 | D004396:Coloring Agents; D009211:Myoglobin; D011506:Proteins; D012709:Serum Albumin; D012710:Serum Albumin, Bovine |
New advances in focal therapy for early stage prostate cancer. | Prostate focal therapy offers men the opportunity to achieve oncological control while preserving sexual and urinary function. The prerequisites for successful focal therapy are to accurately identify, localize and completely ablate the clinically significant cancer(s) within the prostate. We aim to evaluate the eviden... | 10.1080/14737140.2017.1345630 | 28,635,336 | D055011:Ablation Techniques; D000954:Antigens, Surface; D001706:Biopsy; D043425:Glutamate Carboxypeptidase II; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009367:Neoplasm Staging; D018579:Patient Selection; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms; D018084:Ultrasonography... | Expert review of anticancer therapy | 2,017 | D000954:Antigens, Surface; C473848:FOLH1 protein, human; D043425:Glutamate Carboxypeptidase II |
Anatomy of the optic canal: a computed tomography study of endoscopic nerve decompression. | OBJECTIVES
Endoscopic optic nerve decompression has variable success rates. Our goal was to further delineate the radiographic anatomy of the optic canal to determine whether the variable success can be explained on anatomic principles.
METHODS
The optic canal dimensions and the degree of optic canal exposure to the ... | 10.1177/000348940911801203 | 20,112,517 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D019299:Decompression, Surgical; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D009900:Optic Nerve; D012189:Retrospective Studies; D012737:Sex Fac... | The Annals of otology, rhinology, and laryngology | 2,009 | |
Non-invasive imaging of human embryos to predict developmental competence. | Although some aspects of human embryo development are conserved with those of other species, including the mouse, many aspects such as the timing of reprogramming and occurrence in the absence of transcription, duration of transcriptional silence and identity of genes with modulated expression in the oocyte to embryo t... | 10.1016/j.placenta.2011.07.005 | 21,802,136 | D000818:Animals; D001755:Blastocyst; D003952:Diagnostic Imaging; D047108:Embryonic Development; D005260:Female; D006801:Humans; D007246:Infertility; D051379:Mice; D008954:Models, Biological; D011247:Pregnancy; D011379:Prognosis; D011786:Quality Control; D060728:Reproductive Health | Placenta | 2,011 | |
A novel plant homeodomain protein interacts in a functionally relevant manner with a virus movement protein. | Tomato bushy stunt virus and its cell-to-cell movement protein (MP; P22) provide valuable tools to study trafficking of macromolecules through plants. This study shows that wild-type P22 and selected movement-defective P22 amino acid substitution mutants were equivalent for biochemical features commonly associated with... | 10.1104/pp.004754 | 12,177,465 | D000595:Amino Acid Sequence; D001692:Biological Transport; D002352:Carrier Proteins; D018398:Homeodomain Proteins; D016350:Leucine Zippers; D008969:Molecular Sequence Data; D009154:Mutation; D025941:Protein Interaction Mapping; D012333:RNA, Messenger; D012441:Saccharomyces cerevisiae; D014026:Nicotiana; D017864:Tombusv... | Plant physiology | 2,002 | D002352:Carrier Proteins; D018398:Homeodomain Proteins; D012333:RNA, Messenger; D014764:Viral Proteins |
Enhanced anti-colon cancer efficacy of 5-fluorouracil by epigallocatechin-3- gallate co-loaded in wheat germ agglutinin-conjugated nanoparticles. | Colon adenocarcinoma is the third most common cause of cancer-related deaths worldwide owing to its aggressive nature. Here, we developed a novel oral drug delivery system (DDS) that comprised active targeted nanoparticles made from gelatin and chitosan (non-toxic polymers). The nanoparticles were fabricated using a co... | 10.1016/j.nano.2019.102068 | 31,374,249 | D000818:Animals; D017209:Apoptosis; D002392:Catechin; D003110:Colonic Neoplasms; D005472:Fluorouracil; D019073:HT29 Cells; D006801:Humans; D051379:Mice; D058726:Nanoconjugates; D009389:Neovascularization, Pathologic; D014909:Wheat Germ Agglutinins; D023041:Xenograft Model Antitumor Assays | Nanomedicine : nanotechnology, biology, and medicine | 2,019 | D058726:Nanoconjugates; D014909:Wheat Germ Agglutinins; D002392:Catechin; C045651:epigallocatechin gallate; D005472:Fluorouracil |
Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane. | Chemotaxis of human T lymphoblastoma cells of the Tsup-1 line, which migrate similarly to blood T cells, through a layer of basement membrane-like Matrigel on a polycarbonate micropore filter was evoked by vasoactive intestinal peptide (VIP; concentration for a maximal response, 10(-7)M), IL-2 (10(-9)M), and the chemok... | 8,598,457 | D001485:Basement Membrane; D002465:Cell Movement; D002634:Chemotaxis, Leukocyte; D003094:Collagen; D017364:Collagenases; D004338:Drug Combinations; D005109:Extracellular Matrix; D006801:Humans; D007797:Laminin; D020781:Matrix Metalloproteinase 1; D008567:Membranes, Artificial; D011509:Proteoglycans; D013601:T-Lymphocyt... | Journal of immunology (Baltimore, Md. : 1950) | 1,996 | D004338:Drug Combinations; D007797:Laminin; D008567:Membranes, Artificial; D011509:Proteoglycans; C059485:matrigel; D003094:Collagen; D017364:Collagenases; D020781:Matrix Metalloproteinase 1 | |
Effects of detergents on the conformation of Escherichia coli tRNA as measured by circular dichroism. | The effect of a cationic detergent, lauryl pyridiniumchloride (LPC), and an anionic one, sodium n-octylbenzenesulfonate (SOBS), on the conformation of unfractionated Escherichia coli tRNA was investigated at various molar ratios of detergent to tRNA (D/R) in the presence and absence of Mg2+ and Na+ ions by measuring th... | 10.1093/oxfordjournals.jbchem.a131551 | 328,496 | D001557:Benzenesulfonates; D002942:Circular Dichroism; D003902:Detergents; D004926:Escherichia coli; D008274:Magnesium; D009690:Nucleic Acid Conformation; D011726:Pyridinium Compounds; D012329:RNA, Bacterial; D012343:RNA, Transfer; D012964:Sodium; D013696:Temperature; D013873:Thionucleotides | Journal of biochemistry | 1,977 | D001557:Benzenesulfonates; D003902:Detergents; D011726:Pyridinium Compounds; D012329:RNA, Bacterial; D013873:Thionucleotides; D012343:RNA, Transfer; D012964:Sodium; D008274:Magnesium |
Consumption of anti-infective drugs in Bulgaria for the period from 1979 to 1994. | The use of systemic antibacterial drugs in Bulgaria for the period from 1979 to 1994 had been studied using the Defined Daily Doses (DDD) methodology. The total consumption of antibacterials, the consumption by therapeutic groups and preparations were presented. The usage of anti-infectives in Bulgaria was growing duri... | 10.1023/a:1008636908431 | 9,151,348 | D000890:Anti-Infective Agents; D002031:Bulgaria; D004363:Drug Utilization; D006801:Humans | Pharmacy world & science : PWS | 1,997 | D000890:Anti-Infective Agents |
Prolonged foetal retention in a bitch resulting in trichogranulomatuous panmetritis and re-establishment of fertility after unilateral ovariohysterectomy. | This case report describes the clinical course, the diagnostic and therapeutic management as well as histopathological findings in a case of foetal retention for about 5 months in a 5-year-old Boxer. Clinical symptoms included mucosanguinous vaginal discharge and a firm ovoid mass of about duck egg size palpable in mid... | 10.1111/j.1439-0531.2007.00850.x | 18,199,268 | D000818:Animals; D001947:Breeding; D004283:Dog Diseases; D004285:Dogs; D004716:Endometritis; D005260:Female; D005298:Fertility; D005333:Fetus; D007044:Hysterectomy; D010052:Ovariectomy; D011247:Pregnancy; D011256:Pregnancy Outcome | Reproduction in domestic animals = Zuchthygiene | 2,008 | |
Only the DNA binding and transactivation domains of c-Myb are required to block terminal differentiation of murine erythroleukemia cells. | The c-Myb protein is a transcription factor with an apparent but poorly defined role in hematopoietic cell growth and differentiation. The DNA binding and several transcriptional regulatory domains of the c-Myb protein have been defined by transient transfections into nonhematopoietic cell lines. Although the relations... | 10.1128/mcb.13.6.3505-3513.1993 | 8,497,265 | D000081:Acetamides; D000818:Animals; D001483:Base Sequence; D002454:Cell Differentiation; D002467:Cell Nucleus; D004268:DNA-Binding Proteins; D005622:Friend murine leukemia virus; D017353:Gene Deletion; D004915:Leukemia, Erythroblastic, Acute; D051379:Mice; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleot... | Molecular and cellular biology | 1,993 | D000081:Acetamides; D004268:DNA-Binding Proteins; D009838:Oligodeoxyribonucleotides; D016376:Oligonucleotides, Antisense; D011518:Proto-Oncogene Proteins; D020598:Proto-Oncogene Proteins c-myb; D012333:RNA, Messenger; C014026:hexamethylene bisacetamide |
Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase. | Radiotherapy is increasingly used in the treatment of joint diseases, but limited information is available on the effects of radiation on cartilage. Here, we characterize the molecular mechanisms leading to cellular senescence in irradiated primary cultured articular chondrocytes. Ionizing radiation (IR) causes activat... | 10.1074/jbc.M109.058628 | 19,887,452 | D000818:Animals; D002356:Cartilage; D002478:Cells, Cultured; D016922:Cellular Senescence; D019902:Chondrocytes; D015853:Cysteine Proteinase Inhibitors; D004789:Enzyme Activation; D005720:Gamma Rays; D006801:Humans; D007592:Joint Diseases; D007976:Leupeptins; D048670:MAP Kinase Kinase 4; D020935:MAP Kinase Signaling Sys... | The Journal of biological chemistry | 2,010 | D015853:Cysteine Proteinase Inhibitors; D007976:Leupeptins; D061988:Proteasome Inhibitors; D017382:Reactive Oxygen Species; D048051:p38 Mitogen-Activated Protein Kinases; D048670:MAP Kinase Kinase 4; D046988:Proteasome Endopeptidase Complex; C061553:ATP dependent 26S protease; C447939:SIRT1 protein, human; D056564:Sirt... |
Noninvasive detection of acute renal allograft rejection by measurement of soluble Tim-3 in urine. | The purpose of the present study was to assess whether urinary soluble T-cell immunoglobulin and mucin domain-containing protein 3 (sTim-3) could be adopted as a novel non‑invasive biomarker for acute rejection (AR) following renal transplantation. A total of 156 patients were enrolled between January 2006 and December... | 10.3892/mmr.2017.6670 | 28,586,044 | D000208:Acute Disease; D000328:Adult; D015415:Biomarkers; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006084:Graft Rejection; D006680:HLA Antigens; D000072597:Hepatitis A Virus Cellular Receptor 2; D006801:Humans; D007518:Isoantibodies; D007677:Kidney Function Tests; D016030:Kidney Transplantation; D008... | Molecular medicine reports | 2,017 | D015415:Biomarkers; C448908:HAVCR2 protein, human; D006680:HLA Antigens; D000072597:Hepatitis A Virus Cellular Receptor 2; D007518:Isoantibodies |
Minimally Invasive Video-Assisted Thyroidectomy: Analysis of Complications From a Systematic Review. | BACKGROUND
Nowadays, minimally invasive video-assisted thyroidectomy (MIVAT) is considered a safe and effective option. However, its complication rate has not been specifically discussed yet. The aim of this systematic review was enrolling a large number of studies to estimate early and late complications (transient an... | 10.1177/1553350618823425 | 30,632,464 | D006801:Humans; D019060:Minimally Invasive Surgical Procedures; D011183:Postoperative Complications; D013965:Thyroidectomy; D020535:Video-Assisted Surgery | Surgical innovation | 2,019 | |
The N200 enhancement effect in reading Chinese is modulated by actual writing. | Previous research has demonstrated that writing can modulate the orthographic processing of reading in Chinese. We examined whether such a modulatory effect from Chinese writing to reading can occur even when visual feedback is not provided during writing. Using the repetition prime paradigm in conjunction with imagine... | 10.1016/j.neuropsychologia.2020.107462 | 32,278,695 | D002681:China; D006801:Humans; D010364:Pattern Recognition, Visual; D011932:Reading; D014956:Writing | Neuropsychologia | 2,020 | |
MDMF: Predicting miRNA-Disease Association Based on Matrix Factorization with Disease Similarity Constraint. | MicroRNAs (miRNAs) have drawn enormous attention owing to their significant roles in various biological processes, as well as in the pathogenesis of human diseases. Therefore, predicting miRNA-disease associations is a pivotal task for the early diagnosis and better understanding of disease pathogenesis. To date, numer... | 10.3390/jpm12060885 | 35,743,670 | Journal of personalized medicine | 2,022 | ||
Comparison of the effects of clonidine and yohimbine on spontaneous pupillary fluctuations in healthy human volunteers. | RATIONALE
Spontaneous fluctuations in the size of the pupil in darkness are a recognized index of sleepiness, and these fluctuations can be quantitatively measured using the pupillographic sleepiness test (PST). The central noradrenergic system is believed to play a role in the maintenance of alertness, and there is ev... | 10.1007/s002130000398 | 10,867,980 | D000293:Adolescent; D000316:Adrenergic alpha-Agonists; D000317:Adrenergic alpha-Antagonists; D000328:Adult; D000704:Analysis of Variance; D001143:Arousal; D001794:Blood Pressure; D003000:Clonidine; D006801:Humans; D008297:Male; D009184:Mydriatics; D011680:Pupil; D012472:Salivation; D015016:Yohimbine | Psychopharmacology | 2,000 | D000316:Adrenergic alpha-Agonists; D000317:Adrenergic alpha-Antagonists; D009184:Mydriatics; D015016:Yohimbine; D003000:Clonidine |
Dissipative soliton resonance mode-locked all-polarization-maintaining double clad Er:Yb fiber laser. | Our first demonstration of an all-PM fiber double clad erbium-ytterbium figure-8 laser mode-locked in a dissipative soliton resonance regime is presented. The laser generated µJ-level rectangular-shaped pulses with a maximum average output power of 1 W at 994 kHz repetition rate. The proposed configuration was characte... | 10.1364/OE.25.024853 | 29,041,158 | Optics express | 2,017 | ||
CD19-targeting fusion protein combined with PD1 antibody enhances anti-tumor immunity in mouse models. | In our previous studies, using a B cell vaccine (scFv-Her2), the targeting of tumor-associated antigen Her2 (human epidermal growth factor receptor-2) to B cells via the anti-CD19 single chain variable fragment (scFv) was shown to augment tumor-specific immunity, which enhanced tumor control in the prophylactic and the... | 10.1080/2162402X.2020.1747688 | 32,363,119 | D000818:Animals; D018941:Antigens, CD19; D001402:B-Lymphocytes; D019496:Cancer Vaccines; D045744:Cell Line, Tumor; D003110:Colonic Neoplasms; D005260:Female; D008325:Mammary Neoplasms, Experimental; D051379:Mice; D008807:Mice, Inbred BALB C; D018719:Receptor, ErbB-2; D011993:Recombinant Fusion Proteins | Oncoimmunology | 2,020 | D018941:Antigens, CD19; C000604812:CD19 antigen, mouse; D019496:Cancer Vaccines; D011993:Recombinant Fusion Proteins; C524056:Erbb2 protein, mouse; D018719:Receptor, ErbB-2 |
Core Recommendations for Osteoarthritis Care: A Systematic Review of Clinical Practice Guidelines. | OBJECTIVE
To evaluate the quality of clinical practice guidelines (CPGs) for interventions in management of osteoarthritis (OA) and to provide a synthesis of high-quality CPG recommendations.
METHODS
Five databases (OvidSP Medline, Cochrane, Cumulative Index to Nursing and Allied Health Literature [CINAHL], Embase, a... | 10.1002/acr.25101 | 36,762,545 | D006801:Humans; D000293:Adolescent; D010003:Osteoarthritis; D026741:Physical Therapy Modalities; D006225:Hand; D007719:Knee Joint; D035002:Lower Extremity | Arthritis care & research | 2,023 | |
Topological liquid diode. | The last two decades have witnessed an explosion of interest in the field of droplet-based microfluidics for their multifarious applications. Despite rapid innovations in strategies to generate small-scale liquid transport on these devices, the speed of motion is usually slow, the transport distance is limited, and the... | 10.1126/sciadv.aao3530 | 29,098,182 | Science advances | 2,017 | ||
Ventilator-Associated Pneumonia in Immunosuppressed Patients. | Immunocompromised patients-including patients with cancer, hematological malignancies, solid organ transplants and individuals receiving immunosuppressive therapies for autoimmune diseases-account for an increasing proportion of critically-ill patients. While their prognosis has improved markedly in the last decades, t... | 10.3390/antibiotics12020413 | 36,830,323 | Antibiotics (Basel, Switzerland) | 2,023 | ||
Time to treat the climate and nature crisis as one indivisible global health emergency. | Over 200 health journals call on the United Nations, political leaders, and health professionals to recognise that climate change and biodiversity loss are one indivisible crisis and must be tackled together to preserve health and avoid catastrophe. This overall environmental crisis is now so severe as to be a global h... | 10.12688/f1000research.144028.1 | 37,900,199 | F1000Research | 2,023 | ||
Management of a patient with lumbar segmental instability using a clinical predictor rule. | The diagnosis of low back pain is a common and costly condition in primary healthcare, which is often grouped into a homogeneous category. It has been suggested that the population of patients with low back pain are not a homogenous group and that they should be classified into subgroups. One subgroup identified in the... | 10.1007/s11420-013-9351-y | 24,426,882 | HSS journal : the musculoskeletal journal of Hospital for Special Surgery | 2,013 | ||
Sexual violence and abuse and the care programme approach. | In 2008 it became policy that all those on the care programme approach were assessed for sexual violence/abuse. The implementation of this policy was assessed 8 years on. The findings of a survey and data request to Health and Social Care Information Centre are disappointing. We argue that this important initiative nee... | 10.1192/bjp.bp.116.186122 | 27,802,976 | D004739:England; D006801:Humans; D008605:Mental Health Services; D009313:National Health Programs; D012742:Sex Offenses | The British journal of psychiatry : the journal of mental science | 2,016 | |
Ion aggregation in concentrated aqueous and methanol solutions of polyoxometallates Keggin anions: the effect of counterions investigated by molecular dynamics simulations. | Aqueous solutions of the polyoxometallate alpha-PW(12)O(40)(3-) Keggin anion "PW(3-)" have been simulated by molecular dynamics, comparing two anion concentrations (0.06 and ca. 0.15 mol l(-1)) and Cs(+), NBu(4)(+), UO(2)(2+), Eu(3+), H(3)O(+) and H(5)O(2)(+) as neutralizing M(n+) counterions. They reveal marked counte... | 10.1039/b810440a | 19,030,589 | Physical chemistry chemical physics : PCCP | 2,008 | ||
Dexamethasone-facilitated postponement of delivery of an extremely preterm pregnancy complicated by the syndrome of hemolysis, elevated liver enzymes, and low platelets. | OBJECTIVE
Patients with severe preeclampsia and the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome) are at increased risk for perinatal and maternal morbidity, especially in very preterm gestations. When this condition affects a pregnancy on the cusp of viability, a therapeutic interve... | 10,226,464 | D000328:Adult; D000893:Anti-Inflammatory Agents; D003907:Dexamethasone; D005260:Female; D017359:HELLP Syndrome; D006801:Humans; D007770:L-Lactate Dehydrogenase; D007752:Obstetric Labor, Premature; D010976:Platelet Count; D011247:Pregnancy; D012307:Risk Factors; D013997:Time Factors | Military medicine | 1,999 | D000893:Anti-Inflammatory Agents; D003907:Dexamethasone; D007770:L-Lactate Dehydrogenase | |
Chymotrypsin C (caldecrin) is associated with enamel development. | Two main proteases cleave enamel extracellular matrix proteins during amelogenesis. Matrix metalloprotease-20 (Mmp20) is the predominant enzyme expressed during the secretory stage, while kallikrein-related peptidase-4 (Klk4) is predominantly expressed during maturation. Mutations to both Mmp20 and Klk4 result in abnor... | 10.1177/0022034511418231 | 21,828,354 | D000566:Amelogenesis; D000818:Animals; D015153:Blotting, Western; D002918:Chymotrypsin; D003746:Dental Enamel Proteins; D004658:Enamel Organ; D018507:Gene Expression Regulation, Developmental; D007610:Kallikreins; D008297:Male; D053519:Matrix Metalloproteinase 20; D016133:Polymerase Chain Reaction; D012333:RNA, Messeng... | Journal of dental research | 2,011 | D003746:Dental Enamel Proteins; D012333:RNA, Messenger; C109069:enamel matrix proteins; D007610:Kallikreins; C120801:kallikrein 4; D002918:Chymotrypsin; C117569:chymotrypsin C; D053519:Matrix Metalloproteinase 20 |
Influence social and healthcare support on psychiatric adverse events in MDR-TB patient. | INTRODUCTION
Multidrug resistance tuberculosis (MDR-TB) is a continuing threat because the treatment is rather toxic. One of the causes of poor treatment outcome is due to the adverse events, especially the occurrence of psychiatric adverse events.
METHODOLOGY
The two cases presented in this paper are MDR-TB patients... | 10.3855/jidc.10352 | 31,954,010 | Journal of infection in developing countries | 2,018 | ||
Excellent Thermoelectric Performance of 2D CuMN2 (M = Sb, Bi; N = S, Se) at Room Temperature. | 2D copper-based semiconductors generally possess low lattice thermal conductivity due to their strong anharmonic scattering and quantum confinement effect, making them promising candidate materials in the field of high-performance thermoelectric devices. In this work, we proposed four 2D copper-based materials, namely ... | 10.3390/ma15196700 | 36,234,041 | Materials (Basel, Switzerland) | 2,022 | ||
Structure-activity relationships of HIV-1 protease inhibitors containing gem-diaminoserine core unit. | Two series of peptidomimetics containing 1,1-diamino-2-hydroxyethane (gSer) core structure were prepared, from amino acid starting materials, and evaluated as inhibitors of HIV-1 protease (HIV-1 Pr). Asymmetrical pseudodipeptides, Y-Xaa-gSer-Y (Y = Z, Fmoc; Xaa = Cha, Phe, Tyr, Tic) showed weak inhibitory potency (IC50... | 9,689,433 | D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004983:Ethanolamines; D016333:HIV Protease; D017320:HIV Protease Inhibitors; D006801:Humans; D006865:Hydrogenation; D018716:Molecular Mimicry; D010455:Peptides; D013329:Structure-Activity Relationship; D014269:Trifluoroacetic Acid | Arzneimittel-Forschung | 1,998 | D004983:Ethanolamines; D017320:HIV Protease Inhibitors; D010455:Peptides; D014269:Trifluoroacetic Acid; D016333:HIV Protease | |
Human lung tumours may coexpress different classes of intermediate filaments. | Ninety four pulmonary neoplasms were examined immunocytochemically with two or three different monoclonal antibodies against the intermediate filament proteins cytokeratin, neurofilament, vimentin, and desmin. In normal tissues these have a different and non-overlapping distribution, and it is generally believed that t... | 10.1136/jcp.39.9.950 | 3,020,094 | D000230:Adenocarcinoma; D000911:Antibodies, Monoclonal; D018288:Carcinoma, Small Cell; D002294:Carcinoma, Squamous Cell; D006801:Humans; D007381:Intermediate Filament Proteins; D008175:Lung Neoplasms | Journal of clinical pathology | 1,986 | D000911:Antibodies, Monoclonal; D007381:Intermediate Filament Proteins |
[Hemostatic disturbances in chronic myeloid leukemia]. | UNLABELLED
Chronic myeloid leukemia (CML) is one of the chronic myeloproliferative disorders. Haemostatic disturbances and infections are the main causes of death in CML.
MATERIAL AND METHODS
We investigated 22 patients with CML aged 38-55 years (median 45.0). Twenty nine healthy controls were sex and age-matched. Pa... | 17,726,865 | D000328:Adult; D001777:Blood Coagulation; D001798:Blood Proteins; D016022:Case-Control Studies; D005260:Female; D006403:Hematologic Tests; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive; D008297:Male; D008875:Middle Aged; D015539:Platelet Activation; D011044:Poland | Wiadomosci lekarskie (Warsaw, Poland : 1960) | 2,007 | D001798:Blood Proteins | |
Appearance of noncompaction-like remodeling of the anatomical right ventricle in a middle-aged subject with modified transposition of the great arteries who did not undergo surgery. | We describe noncompaction-like remodeling of the anatomical right ventricle (ARV) in a middle-aged subject with modified transposition of the great arteries (TGA). A 54 year-old male had been diagnosed with modified TGA at age 40, but no surgery was performed. Enhanced multislice CT revealed the ascending aorta coursin... | 10.1016/j.ijcard.2006.11.034 | 17,222,471 | D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D009206:Myocardium; D014057:Tomography, X-Ray Computed; D014188:Transposition of Great Vessels; D016278:Ventricular Function, Right; D017725:Ventricular Pressure; D020257:Ventricular Remodeling | International journal of cardiology | 2,007 | |
Inferring the directionality of coupling with conditional mutual information. | Uncovering the directionality of coupling is a significant step in understanding drive-response relationships in complex systems. In this paper, we discuss a nonparametric method for detecting the directionality of coupling based on the estimation of information theoretic functionals. We consider several different meth... | 10.1103/PhysRevE.77.026214 | 18,352,110 | Physical review. E, Statistical, nonlinear, and soft matter physics | 2,008 | ||
A founder AGL mutation causing glycogen storage disease type IIIa in Inuit identified through whole-exome sequencing: a case series. | BACKGROUND
Glycogen storage disease type III is caused by mutations in both alleles of the AGL gene, which leads to reduced activity of glycogen-debranching enzyme. The clinical picture encompasses hypoglycemia, with glycogen accumulation leading to hepatomegaly and muscle involvement (skeletal and cardiac). We sought ... | 10.1503/cmaj.140840 | 25,602,008 | D002170:Canada; D016022:Case-Control Studies; D002675:Child, Preschool; D015331:Cohort Studies; D004252:DNA Mutational Analysis; D059472:Exome; D005260:Female; D018703:Founder Effect; D006004:Glycogen Debranching Enzyme System; D006010:Glycogen Storage Disease Type III; D006801:Humans; D007223:Infant; D004930:Inuit; D0... | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | 2,015 | D006004:Glycogen Debranching Enzyme System |
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