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Tumor enhancement of colorectal liver metastases on preoperative gadobutrol-enhanced MRI at 5 minutes post-contrast injection is associated with overall survival post-hepatectomy.
Previous studies have demonstrated that target tumor enhancement (TTE) of colorectal cancer liver metastases (CRCLM) on 10-minute delayed phase gadobutrol-enhanced MRI is associated with overall survival post-hepatectomy. The purpose of this study was to determine whether TTE of CRCLM on preoperative gadobutrol-enhance...
10.21037/qims.2018.10.15
30,976,555
Quantitative imaging in medicine and surgery
2,019
The thresholds of the jaw-opening reflex and trigeminal brainstem neurons to tooth-pulp stimulation in acutely and chronically prepared cats.
Electrical stimuli were applied to tooth-pulp in cats and the thresholds of the jaw-opening reflex and of neurons in the trigeminal sensory nuclei were determined. The effects of the method of preparation of the animal for stereotaxic recording were determined by making observations on animals set up in one of three wa...
10.1016/0306-4522(90)90354-7
2,215,914
D000758:Anesthesia; D000818:Animals; D001930:Brain Injuries; D001933:Brain Stem; D002415:Cats; D003782:Dental Pulp; D004558:Electric Stimulation; D004566:Electrodes; D004576:Electromyography; D005260:Female; D007568:Jaw; D008297:Male; D009474:Neurons; D010146:Pain; D012018:Reflex; D012684:Sensory Thresholds; D013238:St...
Neuroscience
1,990
Rapidly Progressive Intracranial Vasculopathy in Graft Versus Host Disease.
After allogenic hematopoietic stem cell transplantation, cerebrovascular complications are uncommon, occurring in approximately 2%, and typically due to coagulopathy or infection. Graft versus host disease has been rarely reported to affect the central nervous system but these cases typically describe leukoencephalopat...
10.1016/j.jstrokecerebrovasdis.2019.02.017
30,878,370
D001706:Biopsy; D002561:Cerebrovascular Disorders; D018450:Disease Progression; D017809:Fatal Outcome; D006086:Graft vs Host Disease; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D006965:Hyperplasia; D015451:Leukemia, Lymphocytic, Chronic, B-Cell; D008297:Male; D008875:Middle Aged; D058426:Neointima...
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2,019
Mismatched fluorescent probes with an enhanced strand displacement reaction rate for intracellular long noncoding RNA imaging.
We design mismatched fluorescent probes to directly monitor the long noncoding RNA (lncRNA) in living cells. The introduction of mismatched bases in the fluorescent probe greatly enhances the strand displacement reaction rate toward the target lncRNA. These mismatched probes can monitor the intracellular lncRNA express...
10.1039/d1cc05270e
35,037,666
D005456:Fluorescent Dyes
Chemical communications (Cambridge, England)
2,022
D005456:Fluorescent Dyes
Methylglyoxal-derived stress: An emerging biological factor involved in the onset and progression of cancer.
Cancer is a disease characterised by uncontrolled growth and proliferation of cells. Tumours primarily show a higher rate of glucose uptake for lactate production even in the presence of functional mitochondria. An important metabolic consequence is intracellular formation of glucose-derived carbonyl reactive species s...
10.1016/j.semcancer.2017.05.010
28,600,198
D000818:Animals; D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D002471:Cell Transformation, Neoplastic; D019008:Drug Resistance, Neoplasm; D020868:Gene Silencing; D006019:Glycolysis; D006031:Glycosylation; D006801:Humans; D007791:Lactoylglutathione Lyase; D011765:Pyruvaldehyde; D015398:Signal Transduction
Seminars in cancer biology
2,018
D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D011765:Pyruvaldehyde; D007791:Lactoylglutathione Lyase
Karyotypic changes in the preclinical and subsequent stages of malignant mesothelioma: a case report.
The karyotypic evolution was evaluated in cells from recurring pleural effusions in a patient previously exposed to asbestos. Pleural malignant mesothelioma (MM) was diagnosed 4 years after the first cytogenetic examination. The primary cytogenetic changes consisted of loss of chromosomes 1p,14,21, Y, both 22, and deri...
10.1016/0165-4608(93)90174-k
7,694,791
D000368:Aged; D000818:Animals; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007124:Immunoenzyme Techniques; D007621:Karyotyping; D007633:Keratins; D008297:Male; D008654:Mesothelioma; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude;...
Cancer genetics and cytogenetics
1,993
D007633:Keratins
[Data protection in telemedicine].
The lawfulness of telemedical applications themselves is beyond question from the point of view of data protection. However demands have to be met in two respects to make the procedures legitimate: On the one hand, the informed consent of the participating patients is necessary, on which high demands have to be made. O...
10.1007/s00105-019-4380-1
30,874,839
D016494:Computer Security; D006801:Humans; D017216:Telemedicine
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
2,019
Effects of dietary potassium and sodium on magnesium utilization in sheep.
Two metabolism trials were conducted to determine the effect of altering dietary Na and K on Mg availability. Three dietary treatments (normal K-normal Na, high K-normal Na and high K-high Na) were imposed upon nine crossbred wether lambs in a randomized block design. Each trial consisted of a 5-d diet adjustment, a 10...
10.2527/jas1985.602578x
3,988,635
D000821:Animal Feed; D000818:Animals; D001682:Biological Availability; D008274:Magnesium; D008297:Male; D011188:Potassium; D012756:Sheep; D012964:Sodium
Journal of animal science
1,985
D012964:Sodium; D008274:Magnesium; D011188:Potassium
Effective active learning in digital pathology: A case study in tumor infiltrating lymphocytes.
BACKGROUND AND OBJECTIVE Deep learning methods have demonstrated remarkable performance in pathology image analysis, but they require a large amount of annotated training data from expert pathologists. The aim of this study is to minimize the data annotation need in these analyses. METHODS Active learning (AL) is an ...
10.1016/j.cmpb.2022.106828
35,500,506
D006801:Humans; D007091:Image Processing, Computer-Assisted; D016246:Lymphocytes, Tumor-Infiltrating; D009369:Neoplasms; D018794:Problem-Based Learning
Computer methods and programs in biomedicine
2,022
Dynamic measurements and simulations of airborne picolitre-droplet coalescence in holographic optical tweezers.
We report studies of the coalescence of pairs of picolitre aerosol droplets manipulated with holographic optical tweezers, probing the shape relaxation dynamics following coalescence by simultaneously monitoring the intensity of elastic backscattered light (EBL) from the trapping laser beam (time resolution on the orde...
10.1063/1.4959901
27,497,560
The Journal of chemical physics
2,016
Pathological findings of pemphigus vulgaris showing giant cobblestone-like conjunctival papillae.
PURPOSE To describe the pathophysiological findings of a patient with pemphigus vulgaris (PV) showing giant conjunctival papillae. METHODS A 64-year-old man who had mucosal-dominant PV with giant conjunctival papillae, resembling those of vernal keratoconjunctivitis (VKC), underwent an ophthalmological workup. The cl...
10.1159/000355374
24,163,678
Case reports in ophthalmology
2,013
A Semi-parametric Bayesian Approach for Differential Expression Analysis of RNA-seq Data.
RNA-sequencing (RNA-seq) technologies have revolutionized the way agricultural biologists study gene expression as well as generated a tremendous amount of data waiting for analysis. Detecting differentially expressed genes is one of the fundamental steps in RNA-seq data analysis. In this paper, we model the count data...
10.1007/s13253-015-0227-0
27,570,441
Journal of agricultural, biological, and environmental statistics
2,015
Disorders of the long head of the biceps tendon.
The functional importance of the long head of the biceps tendon is a source of debate. Despite the controversy concerning its functional role, the long head of the biceps tendon is a recognized pain generator in the shoulder. Because long head of the biceps tendinopathy is commonly associated with other shoulder pathol...
25,745,939
D001182:Arthroscopy; D006801:Humans; D018482:Muscle, Skeletal; D012782:Shoulder; D052256:Tendinopathy; D053656:Tenodesis
Instructional course lectures
2,015
Who pays for continuing education in nursing?
This study examines the determinants of employer support for attendance at nursing continuing education (CE) offerings. The experience of 1,171 nurses was examined in relation to their age, educational background, present job characteristics, and annual income. Position level and income were positively related to the e...
10.3928/0022-0124-19930101-05
8,418,093
D004471:Economics, Nursing; D004509:Education, Nursing, Continuing; D005382:Financing, Personal; D006801:Humans; D007182:Income; D009042:Motivation; D015402:Nursing Education Research; D010559:Personnel Management; D012923:Social Class
Journal of continuing education in nursing
1,993
Corticotropin-releasing hormone (CRH) depresses n-methyl-D-aspartate receptor-mediated current in cultured rat hippocampal neurons via CRH receptor type 1.
CRH, the primary regulator of the neuroendocrine responses to stress, has been shown to modulate synaptic efficacy and the process of learning and memory in hippocampus. However, effects of CRH on N-methyl-d-aspartate (NMDA) receptor, the key receptor for synaptic plasticity, remain unclear. In primary cultured hippoca...
10.1210/en.2007-1378
18,079,206
D000200:Action Potentials; D000262:Adenylyl Cyclases; D000818:Animals; D002478:Cells, Cultured; D003346:Corticotropin-Releasing Hormone; D000242:Cyclic AMP; D017868:Cyclic AMP-Dependent Protein Kinases; D004305:Dose-Response Relationship, Drug; D006624:Hippocampus; D009474:Neurons; D018408:Patch-Clamp Techniques; D0547...
Endocrinology
2,008
C101531:CRF receptor type 2; D018019:Receptors, Corticotropin-Releasing Hormone; D016194:Receptors, N-Methyl-D-Aspartate; C101530:CRF receptor type 1; D003346:Corticotropin-Releasing Hormone; D000242:Cyclic AMP; D017868:Cyclic AMP-Dependent Protein Kinases; D054799:Phospholipase C beta; D000262:Adenylyl Cyclases
Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells.
In the pancreatic islet, serotonin is an autocrine signal increasing beta cell mass during metabolic challenges such as those associated with pregnancy or high-fat diet. It is still unclear whether serotonin is relevant for regular islet physiology and hormone secretion. Here, we show that human beta cells produce and ...
10.1016/j.celrep.2016.11.072
28,009,296
D000818:Animals; D000242:Cyclic AMP; D003920:Diabetes Mellitus; D005934:Glucagon; D050416:Glucagon-Secreting Cells; D005947:Glucose; D006801:Humans; D050417:Insulin-Secreting Cells; D051379:Mice; D011985:Receptors, Serotonin; D012701:Serotonin; D015398:Signal Transduction; D000096642:Receptor, Serotonin, 5-HT1F
Cell reports
2,016
D011985:Receptors, Serotonin; D012701:Serotonin; D005934:Glucagon; D000242:Cyclic AMP; D005947:Glucose
Campylobacter colitis.
Eleven consecutive patients with diarrhoea from whose stools campylobacter were isolated were investigated by sigmoidoscopy and rectal biopsy. Eight had definite proctitis, and in seven biopsy specimens were abnormal with histological changes ranging from non-specific colitis to gross colitis with goblet-cell depletion...
10.1136/bmj.1.6167.857
435,842
D000293:Adolescent; D000328:Adult; D000368:Aged; D002169:Campylobacter Infections; D003092:Colitis; D003967:Diarrhea; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012007:Rectum
British medical journal
1,979
De novo Transcriptome Assembly and Comparison of C3, C3-C4, and C4 Species of Tribe Salsoleae (Chenopodiaceae).
C4 photosynthesis is a carbon-concentrating mechanism that evolved independently more than 60 times in a wide range of angiosperm lineages. Among other alterations, the evolution of C4 from ancestral C3 photosynthesis requires changes in the expression of a vast number of genes. Differential gene expression analyses be...
10.3389/fpls.2017.01939
29,184,562
Frontiers in plant science
2,017
Travelling wave velocity test and Ménière's disease revisited.
Transtympanic Electrocochleography (TT-ECoG) and the glycerol test can aid in the diagnostic process of Ménière's disease (MD). Measurement of travelling wave velocity (TWV) has been proposed as an alternative to TT-ECoG to detect endolymphatic hydrops. We assessed the feasibility and obtained normative data of the TWV...
10.1007/s00405-007-0486-7
18,172,660
D000328:Adult; D001300:Audiometry, Evoked Response; D001301:Audiometry, Pure-Tone; D018159:Endolymphatic Hydrops; D016057:Evoked Potentials, Auditory, Brain Stem; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
2,008
Depression and perceived social support among Saudi patients with multiple sclerosis.
PURPOSE To examine the association between depression level and perceived social support among patients with multiple sclerosis (MS) in Saudi Arabia. DESIGN AND METHODS A cross-sectional, descriptive, correlational design was used with 140 patients. A self-reporting questionnaires were used. FINDINGS The age range ...
10.1111/ppc.12293
29,774,946
D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D003863:Depression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis; D012529:Saudi Arabia; D012944:Social Support; D055815:Young Adult
Perspectives in psychiatric care
2,018
TNF-alpha regulates the effects of irradiation in the mouse bone marrow microenvironment.
BACKGROUND Secondary bone marrow (BM) myelodysplastic syndromes (MDS) are increasingly common, as a result of radio or chemotherapy administered to a majority of cancer patients. Patients with secondary MDS have increased BM cell apoptosis, which results in BM dysfunction (cytopenias), and an increased risk of developi...
10.1371/journal.pone.0008980
20,126,546
D000818:Animals; D057134:Antibodies, Neutralizing; D017209:Apoptosis; D001772:Blood Cell Count; D015153:Blotting, Western; D001853:Bone Marrow; D001854:Bone Marrow Cells; D002460:Cell Line; D004789:Enzyme Activation; D005434:Flow Cytometry; D007962:Leukocytes; D008297:Male; D020782:Matrix Metalloproteinases; D008533:Me...
PloS one
2,010
D057134:Antibodies, Neutralizing; D014409:Tumor Necrosis Factor-alpha; D042461:Vascular Endothelial Growth Factor A; D020782:Matrix Metalloproteinases
Evaluation and Identification of Lumbosacral Transitional Vertebra Causing Intractable Low Back Pain Utilizing Bone Single-Photon Emission Tomography with Computed Tomography.
The cause of low back pain due to lumbosacral transitional vertebra (LSTV) still remains a debated topic. Functional imaging with bone scintigraphy has been a valuable adjunct in its assessment; however, in recent years, the additional utility of single-photon emission tomography with computed tomography (SPECT/CT) is ...
10.4103/1450-1147.215495
29,033,685
World journal of nuclear medicine
2,017
ZebraShare: a new venue for rapid dissemination of zebrafish mutant data.
BACKGROUND In the past decade, the zebrafish community has widely embraced targeted mutagenesis technologies, resulting in an abundance of mutant lines. While many lines have proven to be useful for investigating gene function, many have also shown no apparent phenotype, or phenotypes not of interest to the originating...
10.7717/peerj.11007
33,954,026
PeerJ
2,021
Adverse events following immunization with ChAdOx1 nCoV-19 and BBIBP-CorV vaccine: A comparative study among healthcare professionals of Nepal.
BACKGROUND Adverse events following immunization (AEFI) against SARS-CoV-2 are common as reported by clinical trials and contemporary evidence. The objective of the present study was to evaluate the local and systemic adverse events following vaccination with ChAdOx1 nCoV-19 and BBIBP-CorV among the healthcare professi...
10.1371/journal.pone.0272729
35,947,626
D000328:Adult; D000086382:COVID-19; D000090985:ChAdOx1 nCoV-19; D003430:Cross-Sectional Studies; D003695:Delivery of Health Care; D005221:Fatigue; D005260:Female; D006261:Headache; D006801:Humans; D007114:Immunization; D008297:Male; D009390:Nepal; D010146:Pain; D000086402:SARS-CoV-2; D014611:Vaccination
PloS one
2,022
D000090985:ChAdOx1 nCoV-19
Competing species model with behavioral adaptation.
This paper studies the properties of a modified Lotka-Volterra model for two competing species, in which the coefficients of the interaction terms are time-dependent averages of the level of interaction over the entire past. For this model, it is shown that competitive exclusion does not occur, there are two possible s...
10.1007/BF00275683
3,805,910
D000223:Adaptation, Psychological; D000818:Animals; D003163:Competitive Behavior; D008433:Mathematics; D008960:Models, Psychological; D011156:Population Density
Journal of mathematical biology
1,986
Ganoderma australe from southern India.
The genetic diversity of Ganoderma australe (Fr.) Pat. from southern India was investigated by using ITS1/2 rDNA. The phylogenetic analysis showed that six isolates clustered into two groups viz. biological species I and II. The four strains of BS I (YER03, MYC5, MYC2 and KE) clustered with G. australe TAI-01 and the t...
10.1016/j.micres.2007.01.003
17,462,872
D016000:Cluster Analysis; D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer; D032902:Ganoderma; D007194:India; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
Microbiological research
2,008
D004271:DNA, Fungal; D004275:DNA, Ribosomal; D021903:DNA, Ribosomal Spacer
Role of IL-10 and TNF-α during Mycobacterium tuberculosis infection in murine alveolar macrophages.
Mycobacterium tuberculosis (Mtb) is known to be responsible for tuberculosis (TB), but the pathogenesis of this disease and the host defense mechanisms involved are, for the most part, poorly understood. In this study, we divided 30 male C57BL/6 mice into control and infection groups, and following injection with physi...
10.4238/gmr.15037819
27,706,765
D000818:Animals; D017209:Apoptosis; D016753:Interleukin-10; D016676:Macrophages, Alveolar; D008297:Male; D008810:Mice, Inbred C57BL; D009169:Mycobacterium tuberculosis; D010766:Phosphorylation; D050796:STAT3 Transcription Factor; D014376:Tuberculosis; D014409:Tumor Necrosis Factor-alpha
Genetics and molecular research : GMR
2,016
D050796:STAT3 Transcription Factor; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10
White matter loss and oligodendrocyte dysfunction in HIV: A consequence of the infection, the antiretroviral therapy or both?
While the severe cognitive effects of HIV-associated dementia have been reduced by combined antiretroviral therapy (cART), nearly half of HIV-positive (HIV+) patients still suffer from some form of HIV-Associated Neurocognitive Disorders (HAND). While frank neuronal loss has been dramatically reduced in HAND patients, ...
10.1016/j.brainres.2019.146397
31,442,414
D015526:AIDS Dementia Complex; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections; D006801:Humans; D009186:Myelin Sheath; D015213:Neuroimmunomodulation; D009836:Oligodendroglia; D010523:Peripheral Nervous System Diseases; D019562:Viral Load; D066127:White Matter
Brain research
2,019
Acute pancreatitis and reduction of H+ ion concentration in gastric secretions in experimental acute myocarditis produced by Indian red scorpion, Buthus tamulus, venom.
Crude venom (4 mg/kg) of scorpion (B. tamulus) was given in saline to anaesthetized dogs and rabbits. It produced a reduction in gastric H+ ion concentration in dogs with acute myocarditis. Simultaneously an increase in circulating amylase and lipase level was also observed. However 60% venom poisoned rabbits showed an...
2,606,531
D000208:Acute Disease; D000818:Animals; D004285:Dogs; D005260:Female; D005750:Gastric Juice; D006863:Hydrogen-Ion Concentration; D008297:Male; D009205:Myocarditis; D010195:Pancreatitis; D011817:Rabbits; D012604:Scorpion Venoms; D012605:Scorpions
Indian journal of experimental biology
1,989
D012604:Scorpion Venoms
Complicated anorectal sepsis.
These complex anorectal conditions are difficult to diagnose because clinical features overlap. In general, an aggressive approach is reserved for hidradenitis suppurativa and necrotizing infections. Patients with Crohn's disease, hematologic disorders, or AIDS are often treated more conservatively, but the correct tim...
10.1016/s0039-6109(05)70536-3
9,092,106
D000163:Acquired Immunodeficiency Syndrome; D002081:Buttocks; D003424:Crohn Disease; D005401:Fissure in Ano; D006069:Gonorrhea; D006561:Herpes Simplex; D017497:Hidradenitis Suppurativa; D006801:Humans; D008219:Lymphogranuloma Venereum; D008228:Lymphoma, Non-Hodgkin; D015270:Mycobacterium avium-intracellulare Infection;...
The Surgical clinics of North America
1,997
Regression and recovery of well-developed coronary collateral function in canine hearts after aorta-coronary bypass.
After restoration of antegrade blood flow by coronary artery bypass grafting to a region of myocardium supplied by well-developed collateral vessels, there is regression of collateral supply to that region. There is controversy as to how rapidly this regression occurs, how soon collateral flow might return after an acu...
2,492,626
D000818:Animals; D001794:Blood Pressure; D003097:Collateral Circulation; D001026:Coronary Artery Bypass; D003326:Coronary Circulation; D004285:Dogs; D005260:Female; D008297:Male; D005996:Nitroglycerin; D011184:Postoperative Period
The Journal of thoracic and cardiovascular surgery
1,989
D005996:Nitroglycerin
A novel karyoskeletal protein: characterization of protein NO145, the major component of nucleolar cortical skeleton in Xenopus oocytes.
The nucleolus is a ubiquitous, mostly spheroidal nuclear structure of all protein-synthesizing cells, with a well-defined functional compartmentalization. Although a number of nonribosomal proteins involved in ribosome formation have been identified, the elements responsible for the shape and internal architecture of n...
10.1091/mbc.12.12.3904
11,739,789
D000595:Amino Acid Sequence; D000818:Animals; D002466:Cell Nucleolus; D003001:Cloning, Molecular; D003598:Cytoskeletal Proteins; D013058:Mass Spectrometry; D018613:Microscopy, Confocal; D016253:Microscopy, Immunoelectron; D008969:Molecular Sequence Data; D009865:Oocytes; D009866:Oogenesis; D012333:RNA, Messenger; D0513...
Molecular biology of the cell
2,001
D003598:Cytoskeletal Proteins; D012333:RNA, Messenger; C455108:SYCP2L protein, Xenopus; D029867:Xenopus Proteins
A partisan divide on the uninsured.
The partisan split in Congress over health reform may reflect a broader divide among the public in attitudes toward the uninsured. Despite expert consensus over the harms suffered by the uninsured as a group, Americans disagree over whether the uninsured get the care they need and whether reform legislation providing u...
10.1377/hlthaff.2009.1019
20,223,799
D000367:Age Factors; D034462:Dissent and Disputes; D005260:Female; D019538:Health Care Surveys; D006297:Health Services Accessibility; D054625:Healthcare Disparities; D006801:Humans; D008297:Male; D017057:Medically Uninsured; D009310:National Health Insurance, United States; D011057:Politics; D011639:Public Opinion; D0...
Health affairs (Project Hope)
2,010
Porous poly(L-lactic acid) sheet prepared by stretching with starch particles as filler for tissue engineering.
Porous poly(L-lactic acid) (PLLA) sheets were prepared by uniaxial stretching PLLA sheets containing starch filler. Here, the starch filler content, stretching ratio, stretching rate and stretching temperature are important factors to influence the structure of the porous PLLA sheets, therefore, they have been investig...
26,917,394
D000818:Animals; D001672:Biocompatible Materials; D002460:Cell Line; D051379:Mice; D010006:Osteoblasts; D011091:Polyesters; D016062:Porosity; D013213:Starch; D023822:Tissue Engineering
Carbohydrate polymers
2,016
D001672:Biocompatible Materials; D011091:Polyesters; C033616:poly(lactide); D013213:Starch
Anterior Approach Following Intraoperative Reduction for Cervical Facet Fracture and Dislocation.
OBJECTIVE The purpose of this study was to evaluate the efficacy of the anterior approach following intraoperative reduction under general anesthesia in patients with cervical facet fracture and dislocation. METHODS Twenty-three patients with single level cervical facet fracture and dislocation who were subjected to ...
10.3340/jkns.2019.0139
31,805,759
Journal of Korean Neurosurgical Society
2,020
Pegylated liposomal doxorubicin, melphalan and prednisone therapy for elderly patients with multiple myeloma.
Melphalan & Prednisone (MP) is considered as the standard therapy for Multiple Myeloma (MM) patients not eligible for high-dose therapy. Here, we report the results of a phase I-II study to evaluate the feasibility and efficacy of the association of PLD to the conventional MP regimen during the first six cycles of the ...
10.1002/hon.790
17,006,969
D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols; D018572:Disease-Free Survival; D004317:Doxorubicin; D005260:Female; D006801:Humans; D007239:Infections; D008297:Male; D020714:Maximum Tolerated Dose; D008558:Melphalan; D009101:Multiple Myeloma; D011092:Polyethylene Glycols...
Hematological oncology
2,006
C506643:liposomal doxorubicin; D011092:Polyethylene Glycols; D004317:Doxorubicin; D008558:Melphalan; D011241:Prednisone
Combined spin filtering actions in hybrid magnetic junctions based on organic chains covalently attached to graphene.
We present a bias-controlled spin-filtering mechanism in spin-valves including a hybrid organic chain/graphene interface. Wet growth conditions of oligomeric molecular chains would usually lead, during standard CMOS-compatible fabrication processes, to the quenching of spintronics properties of metallic spin sources du...
10.1039/d2nr01917e
35,993,375
Nanoscale
2,022
In vivo alterations in drug metabolism and transport pathways in patients with chronic kidney diseases.
STUDY OBJECTIVE This study was designed to prospectively evaluate the in vivo activities of drug transporters, metabolizing enzymes, and pharmacokinetics in patients with chronic kidney diseases (CKD) caused by glomerulonephritis and nonglomerular etiologies. DESIGN A prospective study design. PARTICIPANTS Eighteen...
10.1002/phar.1347
24,038,489
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001692:Biological Transport; D001944:Breath Tests; D016022:Case-Control Studies; D065729:Cytochrome P-450 CYP2C9; D051544:Cytochrome P-450 CYP3A; D005260:Female; D005480:Flurbiprofen; D005921:Glomerulonephritis; D006801:Humans; D008297:Male; D008875:Middle Aged; ...
Pharmacotherapy
2,014
C065522:4'-hydroxyflurbiprofen; D005480:Flurbiprofen; D016593:Terfenadine; C093230:fexofenadine; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human
The Wellcome Trust population initiative.
This paper describes what the Wellcome Trust has done and aims to do through its population initiative. The Trust is required to spend its funds to improve the physical welfare of mankind, and in this context there can be no more important issue than the rapid changes that are occurring in the human population. The Tru...
9,433,964
D000349:Africa; D005381:Financing, Organized; D006801:Humans; D011153:Population; D012098:Reproduction; D012109:Research Support as Topic; D014146:Training Support; D006113:United Kingdom
Human reproduction (Oxford, England)
1,997
Sacubitril/Valsartan Shows Improvement of the Cardio-Ankle Vascular Index in a Hypertensive Patient.
A 72-year-old man presented to our clinic with hypertension. Arterial stiffness evaluated by cardio ankle vascular index (CAVI) was markedly increased at 13.5. We treated him using 80 mg/day of valsartan for three months. CAVI was decreased from 13.5 to 13.0. However, his BP fluctuations were still high. We changed the...
10.2147/IMCRJ.S422196
37,636,989
International medical case reports journal
2,023
[Pharmacological study of quaternary trimecaine derivatives].
It has been demonstrated in experiments on cats, rabbits, white rats and mice that the quaternary derivatives of trimecaine (QDT) produce a protective and antiarrhythmic action in atrial (acetylcholine and aconitine) and ventricular (aconitine and calcium chloride) fibrillation. The relationship has been found between ...
6,617,835
D000083:Acetanilides; D000200:Action Potentials; D000818:Animals; D000889:Anti-Arrhythmia Agents; D001145:Arrhythmias, Cardiac; D002415:Cats; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D051379:Mice; D009200:Myocardial Contraction; D010210:Papillary Muscles; D011817:Rabbits; D051381:Rats; D014288:Trimecaine
Farmakologiia i toksikologiia
1,983
D000083:Acetanilides; D000889:Anti-Arrhythmia Agents; D014288:Trimecaine
Chlamydia trachomatis-induced apoptosis occurs in uninfected McCoy cells late in the developmental cycle and is regulated by the intracellular redox state.
Infections with the obligate intracellular bacterium Chlamydia trachomatis are characterized by avoidance of fusion between chlamydia-containing endosomes and lysosomes, bacterial persistence and development of post-infectious sequelae. In this report we show that C. trachomatis induces apoptosis in McCoy and HeLa cell...
10.1006/mpat.2001.0460
11,562,170
D000818:Animals; D000975:Antioxidants; D017209:Apoptosis; D001426:Bacterial Proteins; D002460:Cell Line; D002692:Chlamydia trachomatis; D006801:Humans; D020287:In Situ Nick-End Labeling; D051379:Mice; D010084:Oxidation-Reduction; D017382:Reactive Oxygen Species
Microbial pathogenesis
2,001
D000975:Antioxidants; D001426:Bacterial Proteins; D017382:Reactive Oxygen Species
Molecular characterization and phylogenetic relationships among microsporidian isolates infecting silkworm, Bombyx mori using small subunit rRNA (SSU-rRNA) gene sequence analysis.
The life cycle, spore morphology, pathogenicity, tissue specificity, mode of transmission and small subunit rRNA (SSU-rRNA) gene sequence analysis of the five new microsporidian isolates viz., NIWB-11bp, NIWB-12n, NIWB-13md, NIWB-14b and NIWB-15mb identified from the silkworm, Bombyx mori have been studied along with t...
10.2478/s11686-012-0051-4
23,129,193
D000818:Animals; D012831:Bombyx; D016000:Cluster Analysis; D004271:DNA, Fungal; D020459:Genes, rRNA; D008018:Life Cycle Stages; D016814:Microsporidia; D008969:Molecular Sequence Data; D010802:Phylogeny; D012331:RNA, Fungal; D012337:RNA, Ribosomal, 18S; D017422:Sequence Analysis, DNA; D013172:Spores, Fungal; D014774:Vir...
Acta parasitologica
2,012
D004271:DNA, Fungal; D012331:RNA, Fungal; D012337:RNA, Ribosomal, 18S
Pore-scale studies of spontaneous imbibition into oil-saturated porous media.
Spontaneous imbibition phenomenon was modeled using the lattice Boltzmann method (LBM). The model was validated using silicon-etched micromodel and sandpack visualization experiments. The strongly water-wet model saturated with oil (kerosene or mineral oil) was exposed to distilled water in order for a capillary intera...
10.1103/PhysRevE.77.066311
18,643,375
Physical review. E, Statistical, nonlinear, and soft matter physics
2,008
Trace elements in commonly used medicinal plants from Varna region, Bulgaria.
In this study, we assessed the concentrations of some trace and toxic elements (Cd, Pb, Zn, Cu, Ni, Cr, Fe, and Mn) in traditionally used wild medicinal plants: chamomile (Matricaria chamomilla), white yarrow (Achillea millefolium), linden (Tilia sp.), and elder (Sambucus nigra L.) collected from urban and rural region...
10.1007/s11356-020-10463-2
32,808,128
D002031:Bulgaria; D008670:Metals; D010946:Plants, Medicinal; D013057:Spectrum Analysis; D014131:Trace Elements
Environmental science and pollution research international
2,021
D008670:Metals; D014131:Trace Elements
Aortic-Valve Sparing Repair and Homograft and Dacron Pulmonary Reconstruction Long-term After Arterial Switch Operation.
The arterial switch operation is the gold-standard treatment for dextro-transposition of the great arteries. Long-term follow-up data are beginning to reveal its natural history and associated late complications, including various reoperations for those complications. Given the unique anatomy and the increasing longevi...
10.1016/j.cjcpc.2022.06.001
37,969,933
CJC pediatric and congenital heart disease
2,022
Low-density lipoprotein apheresis in a patient with arteriosclerosis obliterans and light chain deposition disease.
A 49-year-old women with arteriosclerosis obliterans (ASO) complicated with light chain deposition disease (LCDD) is described. Renal biopsy showed a diffuse mesangial nodular lesion and tubulointerstitial changes. Congo red and lambda light chain staining were negative; however, the kappa light chain was positive in b...
10.5414/cnp61429
15,224,807
D001162:Arteriosclerosis Obliterans; D001781:Blood Component Removal; D005260:Female; D006801:Humans; D007147:Immunoglobulin Light Chains; D007674:Kidney Diseases; D008875:Middle Aged
Clinical nephrology
2,004
D007147:Immunoglobulin Light Chains
Primary nelfinavir (NFV)-associated resistance mutations during a follow-up period of 108 weeks in protease inhibitor naïve patients treated with NFV-containing regimens in an HIV clinic cohort.
BACKGROUND Nelfinavir (NFV) is a widely prescribed HIV-1 specific protease inhibitor (PI). However, there are only a few reports that have described the long-term effects of NFV-containing regimens, especially with regard to the emergence of drug resistance in inner-city clinics. OBJECTIVES The aim of this study was ...
10.1016/s1386-6532(02)00179-8
12,878,089
D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D019380:Anti-HIV Agents; D015331:Cohort Studies; D024882:Drug Resistance, Viral; D004359:Drug Therapy, Combination; D005260:Female; D015658:HIV Infections; D017320:HIV Protease Inhibitors; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Mol...
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
2,003
D019380:Anti-HIV Agents; D017320:HIV Protease Inhibitors; D018894:Reverse Transcriptase Inhibitors; D019888:Nelfinavir
Long-term follow-up of triple arthrodesis in patients with cerebral palsy.
This study was a long-term retrospective review of patients with cerebral palsy (CP) who had triple arthrodeses as children before 1981. The medical records were reviewed, and the patients were requested to return for reevaluation, during which a radiograph, physical examination, and patient questionnaire were obtained...
10.1097/01241398-199311000-00004
8,245,193
D000293:Adolescent; D000328:Adult; D000843:Ankle Joint; D001174:Arthrodesis; D002547:Cerebral Palsy; D002648:Child; D005531:Foot Deformities, Acquired; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D010146:Pain; D017060:Patient Satisfaction; D016059:Range of Motion, Articular; D012189:Retrospective...
Journal of pediatric orthopedics
1,993
The differential cancer growth associated with anaesthetics in a cancer xenograft model of mice: mechanisms and implications of postoperative cancer recurrence.
Anaesthetics may modify colorectal cancer cell biology which potentially affects long-term survival. This study aims to compare propofol and sevoflurane regarding with the direct anaesthetic effects on cancer malignancy and the indirect effects on host immunity in a cancer xenograft mode of mice. Cultured colon cancer ...
10.1007/s10565-022-09747-9
35,953,652
D006801:Humans; D051379:Mice; D000818:Animals; D015742:Propofol; D000077149:Sevoflurane; D018686:Anesthetics, Intravenous; D019716:Tissue Inhibitor of Metalloproteinase-2; D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D064593:Heterografts; D008070:Lipopolysaccharides; D018938:Caco-2 Cells; D008819:Mice, Nude;...
Cell biology and toxicology
2,023
D015742:Propofol; D000077149:Sevoflurane; D018686:Anesthetics, Intravenous; D019716:Tissue Inhibitor of Metalloproteinase-2; D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D008070:Lipopolysaccharides
New techniques for the evaluation of bladder function.
The various techniques available for the dynamic assessment of bladder function, including uroflowmetry, cystometrography, urethral closure pressure profiles, and sphincteric electromyography are presented. All of these approaches are discussed in terms of the indications for their use and their functions in evaluation...
388,792
D004576:Electromyography; D006801:Humans; D008297:Male; D008722:Methods; D011312:Pressure; D014521:Urethra; D001743:Urinary Bladder; D014554:Urination; D014563:Urodynamics; D014570:Urologic Diseases
The Urologic clinics of North America
1,979
Combined detection of serum matrix metalloproteinase 9, acetyl heparinase and cathepsin L in diagnosis of ovarian cancer.
OBJECTIVE To investigate the clinic values of combining test of serum matrix metalloproteinase 9 (MMP-9), acetyl heparinase (Hpa) and Cathepsin L (CL) in diagnosis of ovarian cancer. METHODS Serum levels of MMP-9, Hpa and CL were detected in a total of 418 cases, including 217 cases with ovarian malignant tumor, 100 ...
10.1007/s11670-012-0067-1
23,359,763
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu
2,012
Assessing 48 SNPs in Hypertensive Paediatric Patients and Young Adults with Review of Genetic Background of Essential Hypertension.
Essential hypertension in paediatric patients and young adults is rising, mostly on account of obesity-related hypertension. Clinically, the difference between obese hypertensive and non-obese hypertensive individuals is evident; yet, the pathophysiology of essential and obesity-related hypertension is multifactorial, ...
10.3390/children9081262
36,010,152
Children (Basel, Switzerland)
2,022
A tetrazine templated method for the synthesis of ternary conjugates.
Conjugation is an important reaction that enables coupling of molecules. Many protocols exist for the synthesis of binary conjugates from two different molecules or for the polyvalent display of a single molecule. There aren't many methods for the synthesis of ternary conjugates. However, methods for ternary conjugatio...
10.1039/c3cc46634e
24,113,332
D000475:Alkenes; D002241:Carbohydrates; D004583:Electrons; D015394:Molecular Structure; D010455:Peptides; D013777:Tetrazoles
Chemical communications (Cambridge, England)
2,013
D000475:Alkenes; D002241:Carbohydrates; D010455:Peptides; D013777:Tetrazoles
Learning Curve for Robot-Assisted Minimally Invasive Thoracoscopic Esophagectomy: Results From 312 Cases.
BACKGROUND Thoracic laparoscopic robot-assisted minimally invasive esophagectomy (RAMIE) was developed in 2003. RAMIE was shown to be safe and oncologically effective. The aim of this study was to assess the learning curve and the proctoring program for a newly introduced surgeon (surgeon 2). METHODS The "learning cu...
10.1016/j.athoracsur.2018.01.038
29,454,718
D000328:Adult; D000368:Aged; D002983:Clinical Competence; D015331:Cohort Studies; D018572:Disease-Free Survival; D016629:Esophagectomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D059032:Learning Curve; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D009426:Netherland...
The Annals of thoracic surgery
2,018
OsDEG10 encoding a small RNA-binding protein is involved in abiotic stress signaling.
Excessive light can be harmful to photosynthetic apparatus since it causes photoinhibition and photooxidation, and plants often encounter hypoxic or anoxic environments when they become submerged by heavy rain or an ensuing flood. In this study, Oryza sativa Differentially Expressed Genes (OsDEGs) from rice under photo...
10.1016/j.bbrc.2009.01.131
19,285,007
D000595:Amino Acid Sequence; D000693:Anaerobiosis; D003080:Cold Temperature; D055864:Droughts; D008027:Light; D008969:Molecular Sequence Data; D012275:Oryza; D009997:Osmotic Pressure; D010940:Plant Proteins; D030821:Plants, Genetically Modified; D016601:RNA-Binding Proteins; D015398:Signal Transduction; D013312:Stress,...
Biochemical and biophysical research communications
2,009
D010940:Plant Proteins; D016601:RNA-Binding Proteins
Selenium redox cycling in the protective effects of organoselenides against oxidant-induced DNA damage.
The biological role of selenium is a subject of intense current interest, and the antioxidant activity of selenoenzymes is now known to be dependent upon redox cycling of selenium within their active sites. Exogenously supplied or metabolically generated organoselenium compounds, capable of propagating a selenium redox...
10.1021/ja037294j
14,982,447
D000975:Antioxidants; D003198:Computer Simulation; D004247:DNA; D004249:DNA Damage; D005021:Ethylamines; D005978:Glutathione; D016566:Organoselenium Compounds; D016877:Oxidants; D010084:Oxidation-Reduction; D030421:Peroxynitrous Acid; D010957:Plasmids; D011199:Potentiometry; D012643:Selenium
Journal of the American Chemical Society
2,004
D000975:Antioxidants; D005021:Ethylamines; D016566:Organoselenium Compounds; D016877:Oxidants; D030421:Peroxynitrous Acid; C056035:phenyl-2-aminoethylselenide; D004247:DNA; D005978:Glutathione; D012643:Selenium
Evaluation of the Chemosensoric Properties of Commercially Available Dog Foods Using Electronic Sensors and GC-MS/O Analysis.
Pet owners think of their animals as part of their family, which further promotes the growth of the pet food market, encouraging pet owners to select nutritious, palatable, and high-quality foods for pets. Therefore, the evaluation of taste and volatile compounds in pet foods is essential to improve palatability. In th...
10.3390/molecules28145509
37,513,381
D004285:Dogs; D000818:Animals; D008401:Gas Chromatography-Mass Spectrometry; D012903:Smell; D000821:Animal Feed; D013649:Taste; D055549:Volatile Organic Compounds; D009812:Odorants; D064367:Olfactometry; D004581:Electronics; D062609:Electronic Nose
Molecules (Basel, Switzerland)
2,023
D055549:Volatile Organic Compounds
Structure and Electronic Properties of Large Oligomeric Heterometallic 3d/CeIV Polyoxometalates.
Merging the rich chemistry of Ce(IV) polyoxometalates (POMs) with that of 3d polyanions remains a challenge due to the strong competition between these highly oxophilic lanthanide cations and 3d metallic ions for coordination to lacunary molecular metal oxides. We report herein the characterization of an unprecedented ...
10.1021/acs.inorgchem.3c02078
37,921,695
Inorganic chemistry
2,023
Just Plain Hot: Examining Summer Daily High Heat Indices and Community-Level Social Vulnerability on Emergency Medical Services On-Scene Responses in San Antonio, Texas, 2015-2018.
Introduction Increased summer heat has a deleterious effect on people's health and the healthcare system. Emergency Medical Services (EMS) are at the healthcare system frontline, responsive to the community and environmental conditions. The present study examined how EMS on-scene response is affected by community-level...
10.7759/cureus.39914
37,404,445
Cureus
2,023
Cooling Activity is Associated with Neurological Outcome in Patients with Severe Cerebrovascular Disease Undergoing Endovascular Temperature Control.
BACKGROUND Neuroprotection through targeted temperature management is currently investigated in patients with severe brain injury in multiple trials. Feedback devices have been shown to precisely reach and maintain target temperature by constantly adjusting cooling activity. We analyzed the association between cooling ...
10.1007/s12028-015-0122-0
25,693,893
D000368:Aged; D001831:Body Temperature; D002543:Cerebral Hemorrhage; D002544:Cerebral Infarction; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D016032:Randomized Controlled Trials as Topic; D013345:Subarachnoid Hemorrhage
Neurocritical care
2,015
Bat defence in lekking ghost swifts (Hepialus humuli), a moth without ultrasonic hearing.
The Hepialidae represents an early branch of the Lepidoptera, whose members lack the ultrasonic hearing and other obvious predator defence systems present in other extant moths. I observed lekking male ghost swifts, Hepialus humuli, being exploited by northern bats, Eptesicus nilssonii, over a hayfield in southern Swed...
10.1098/rspb.1998.0444
9,721,686
D000818:Animals; D002685:Chiroptera; D005426:Flight, Animal; D006309:Hearing; D008297:Male; D009036:Moths; D011235:Predatory Behavior; D014465:Ultrasonics
Proceedings. Biological sciences
1,998
Fluoroless-ureteroscopy for definitive management of distal ureteral calculi: randomized controlled trial.
INTRODUCTION To assess the conversion rate during fluoroless-ureteroscopy (URS) and evaluate the feasibility, safety, and efficacy of fluoroless-URS as a definitive management of distal ureteral calculi. MATERIAL AND METHODS Between May 2013 and August 2015, patients with radio-opaque distal ureteral calculi of ≤ 1 c...
29,524,976
D000293:Adolescent; D000328:Adult; D016009:Chi-Square Distribution; D005260:Female; D005471:Fluoroscopy; D005500:Follow-Up Studies; D006801:Humans; D008096:Lithotripsy; D008297:Male; D019060:Minimally Invasive Surgical Procedures; D061646:Operative Time; D011446:Prospective Studies; D012016:Reference Values; D018570:Ri...
The Canadian journal of urology
2,018
Medical Devices; General and Plastic Surgery Devices; Classification of the Extracorporeal Shock Wave Device for Treatment of Chronic Wounds. Final order.
The Food and Drug Administration (FDA or we) is classifying the extracorporeal shock wave device for treatment of chronic wounds into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the extracorporeal shock wave d...
29,969,205
D002908:Chronic Disease; D018795:Device Approval; D004869:Equipment Safety; D000074059:Extracorporeal Shockwave Therapy; D006801:Humans; D014481:United States; D014947:Wounds and Injuries
Federal register
2,018
Do Dynamic Fat and Fat-Free Mass Changes follow Theoretical Driven Rules in Athletes?
INTRODUCTION Maximizing fat mass (FM) loss while preserving or increasing fat-free mass (FFM) is a central goal for athletic performance but the composition of body weight (BW) changes over time with training are largely unknown. PURPOSE We aimed to analyze FM and FFM contributions to BW changes and to test if these ...
10.1249/MSS.0000000000001332
28,542,004
D015502:Absorptiometry, Photon; D000293:Adolescent; D050218:Body Fat Distribution; D015992:Body Mass Index; D002149:Energy Intake; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D015233:Models, Statistical; D064797:Physical Conditioning, Human; D013177:Sports; D015430:Weight Gain; D015431:W...
Medicine and science in sports and exercise
2,017
Carbon monoxide poisoning from waterpipe smoking: a retrospective cohort study.
OBJECTIVE Waterpipe smoking may increasingly account for unintentional carbon monoxide poisoning, a serious health hazard with high morbidity and mortality. We aimed at identifying waterpipe smoking as a cause for carbon monoxide poisoning in a large critical care database of a specialty care referral center. METHODS...
10.1080/15563650.2017.1375115
28,906,147
D000293:Adolescent; D000328:Adult; D002249:Carbon Monoxide Poisoning; D002263:Carboxyhemoglobin; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D000073867:Water Pipe Smoking; D055815:Young Adult
Clinical toxicology (Philadelphia, Pa.)
2,018
D002263:Carboxyhemoglobin
Testing the retention of attachments for implant overdentures - validation of an original force measurement system.
The aim of this study was to validate an original portable device to measure attachment retention of implant overdentures both in the lab and in clinical settings. The device was built with a digital force measurement gauge (Imada) secured to a vertical wheel stand associated with a customized support to hold and posit...
10.1111/j.1365-2842.2009.02020.x
19,912,482
D015921:Dental Implants; D017268:Dental Prosthesis Retention; D019094:Dental Prosthesis, Implant-Supported; D003799:Dental Stress Analysis; D003828:Denture, Overlay; D006801:Humans; D055595:Mechanical Phenomena
Journal of oral rehabilitation
2,010
D015921:Dental Implants
Assessing the impact of institution-specific guidelines for antimicrobials on doctors' prescribing behavior at a German tertiary-care center and the additional benefits of providing a mobile application.
OBJECTIVE To assess usage patterns, perceived usability, and effects of institution-specific guidelines (ISGs) for antimicrobials on clinicians' prescribing behavior and the additional benefits of the mobile application (app), a single-center survey among medical doctors was performed. METHODS The study was carried o...
10.1371/journal.pone.0241642
33,141,858
D000328:Adult; D000890:Anti-Infective Agents; D003430:Cross-Sectional Studies; D011307:Drug Prescriptions; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D063731:Mobile Applications; D011795:Surveys and Questionnaires; D062606:Tertiary Care Centers
PloS one
2,020
D000890:Anti-Infective Agents
The next generation Internet and health care: a civics lesson for the informatics community.
The Internet provides one of the most compelling examples of the way in which government research investments can, in time, lead to innovations of broad social and economic impact. This paper reviews the history of the Internet's evolution, emphasizing in particular its relationship to medical informatics and to the na...
9,929,176
D003205:Computing Methodologies; D005544:Forecasting; D049673:History, 20th Century; D020407:Internet; D008490:Medical Informatics; D012106:Research; D014481:United States
Proceedings. AMIA Symposium
1,998
Epidermoid cyst of the floor of the mouth.
The characteristics and incidence of dermoid cysts of the floor of the mouth are reviewed. The epidermoid cyst in the sublingual (genioglossal) position is unique because of its size and the advanced age of presentation. The use of preoperative lateral xerography was beneficial in determining the extent of the lesion a...
285,233
D004814:Epidermal Cyst; D006801:Humans; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor; D009062:Mouth Neoplasms
Journal of oral surgery (American Dental Association : 1965)
1,979
Hypnotic interview and age regression procedures in the elicitation of multiple personality symptoms: a simulation study.
Patients diagnosed as suffering from multiple personality (i.e., multiples) behave as though they possess two or more distinct personal identities. When behaving as one identity, these patients often display signs of amnesia for events that occurred while they were behaving as a different identity (Sutcliffe and Jones ...
10.1080/00332747.1986.11024330
3,809,319
D000293:Adolescent; D000328:Adult; D009105:Dissociative Identity Disorder; D005260:Female; D006801:Humans; D006990:Hypnosis; D007406:Interview, Psychological; D008950:MMPI; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D010287:Parent-Child Relations; D012043:Regression, Psychology; D012381:Role Play...
Psychiatry
1,986
A preliminary study of C-reactive protein in the diagnosis and monitoring of Lyme disease.
Concentrations of C-reactive protein (CRP) in the serum of 14 patients suffering from Lyme disease were measured. 86% of these patients were found to have abnormally high concentrations of serum CRP (range 14-158 mg/L). The CRP concentration of a 60-year-old patient abated from 29 mg/L to 13 mg/L after treatment. Resul...
8,988,812
D002097:C-Reactive Protein; D016231:Fluorescence Polarization Immunoassay; D006801:Humans; D008193:Lyme Disease
Biomedical and environmental sciences : BES
1,996
D002097:C-Reactive Protein
Four-dimensional echocardiography and left ventricular systolic strain measured via two-dimensional speckle-tracking for Danon disease: a case series.
BACKGROUND Danon disease is an X-linked multisystemic disorder characterized by skeletal myopathy, cardiomyopathy, and intellectual disability. CASE SUMMARY Herein, we describe two patients affected by Danon disease from the same family, a father (Patient 1) and his daughter (Patient 2). In Patient 1, a short PR inte...
10.1093/ehjcr/ytab443
34,934,899
European heart journal. Case reports
2,021
Neurogenesis potential of oligodendrocyte precursor cells from oligospheres and injured spinal cord.
Severe traumatic spinal cord injury (SCI) leads to long-lasting oligodendrocyte death and extensive demyelination in the lesion area. Oligodendrocyte progenitor cells (OPCs) are the reservoir of new mature oligodendrocytes during damaged myelin regeneration, which also have latent potential for neurogenic regeneration ...
10.3389/fncel.2022.1049562
36,619,671
Frontiers in cellular neuroscience
2,022
The association of MHC class I proteins with the 2B4 receptor inhibits self-killing of human NK cells.
The killing activity of NK cells is carried out by several activating NK receptors, which includes NKp46, NKp44, NKp30, NKp80, NKG2D, and 2B4. The ligands of these receptors are either self-derived, pathogen-derived, stress-induced ligands or tumor ligands. Importantly, none of these killer ligands are expressed on NK ...
10.4049/jimmunol.0901572
20,164,429
D000818:Animals; D015703:Antigens, CD; D000071178:CD48 Antigen; D002461:Cell Line, Transformed; D045744:Cell Line, Tumor; D003601:Cytotoxicity Tests, Immunologic; D015536:Down-Regulation; D006131:Growth Inhibitors; D015395:Histocompatibility Antigens Class I; D006801:Humans; D007694:Killer Cells, Natural; D008024:Ligan...
Journal of immunology (Baltimore, Md. : 1950)
2,010
D015703:Antigens, CD; C084093:CD244 protein, human; D000071178:CD48 Antigen; C000604065:CD48 protein, human; C000604066:Cd48 protein, mouse; D006131:Growth Inhibitors; D015395:Histocompatibility Antigens Class I; D008024:Ligands; D011971:Receptors, Immunologic; D000071176:Signaling Lymphocytic Activation Molecule Famil...
Electronic structure and chemical bonding in MO(n)- and MO(n) clusters (M = Mo, W; n = 3-5): a photoelectron spectroscopy and ab initio study.
Photoelectron spectroscopy (PES) and ab initio calculations are combined to investigate the electronic structure of MO(n)- clusters (M = W, Mo; n = 3-5). Similar PES spectra were observed between the W and Mo species. A large energy gap between the first and second PES bands was observed for MO3- and correlated with a ...
10.1021/ja046536s
15,584,749
Journal of the American Chemical Society
2,004
Mechanisms of maurotoxin action on Shaker potassium channels.
Maurotoxin (alpha-KTx6.2) is a toxin derived from the Tunisian chactoid scorpion Scorpio maurus palmatus, and it is a member of a new family of toxins that contain four disulfide bridges (, Eur. J. Biochem. 254:468-479). We investigated the mechanism of the maurotoxin action on voltage-gated K(+) channels expressed in ...
10.1016/S0006-3495(00)76335-1
10,920,011
D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D000818:Animals; D018999:Charybdotoxin; D005260:Female; D015640:Ion Channel Gating; D008390:Markov Chains; D008564:Membrane Potentials; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D009498:Neurotoxins; D009865:Oocytes; D018408:Patch-C...
Biophysical journal
2,000
D009498:Neurotoxins; D026902:Potassium Channel Blockers; D015221:Potassium Channels; D011994:Recombinant Proteins; D012604:Scorpion Venoms; D051637:Shaker Superfamily of Potassium Channels; C104498:maurotoxin; D018999:Charybdotoxin
Actigraphic recordings in quantification of periodic leg movements during sleep in children.
BACKGROUND Periodic limb movement disorder (PLMD) has recently emerged as a relatively frequent and markedly underdiagnosed condition in children that induces arousals and sleep fragmentation and leads to poor learning and behavioral problems. Because a cost-effective and widely available alternative to pediatric polys...
10.1016/j.sleep.2005.02.002
15,978,516
D002648:Child; D002675:Child, Preschool; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D020189:Nocturnal Myoclonus Syndrome; D017286:Polysomnography; D012720:Severity of Illness Index; D012891:Sleep Apnea Syndromes
Sleep medicine
2,005
Semisynthesis of a controlled stimuli-responsive alginate hydrogel.
Benefits of the use of natural polymers include biodegradability, biocompatibility, natural abundance, and unique physicochemical/biological properties. Native alginate was used to semisynthesize a new class of biomaterial in which the physical properties such as swelling and pore size can be chemically tailored for de...
10.1021/bm801316z
19,196,004
D000464:Alginates; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D006863:Hydrogen-Ion Concentration; D046911:Macromolecular Substances; D015394:Molecular Structure; D010316:Particle Size; D013499:Surface Properties
Biomacromolecules
2,009
D000464:Alginates; D046911:Macromolecular Substances; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate
Citalopram and suicidality in adult major depression and anxiety disorders.
The suicide-related data on citalopram from controlled clinical trials in depression and anxiety disorders were analysed. Safety data from placebo-controlled and relapse prevention citalopram trials in depression/major depressive disorder (MDD) and anxiety were searched for specific events relating to fatal suicide, no...
10.1080/08039480600937561
17,038,305
D016907:Adverse Drug Reaction Reporting Systems; D018687:Antidepressive Agents, Second-Generation; D001008:Anxiety Disorders; D015283:Citalopram; D003865:Depressive Disorder, Major; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D011358:Product Surveillance, Postmarketing; D016032:Randomized C...
Nordic journal of psychiatry
2,006
D018687:Antidepressive Agents, Second-Generation; D015283:Citalopram
Prevention of the progression of renal injury in diabetic rodent models with preexisting renal disease with chronic endothelin A receptor blockade.
The endothelin (ET) system has emerged as a therapeutic target for the treatment of diabetic nephropathy (DN). The present study examined whether chronic endothelin A (ETA) receptor blockade with atrasentan prevents the progression of renal injury in two models of DN with preexisting renal disease that exhibit an incre...
10.1152/ajprenal.00182.2018
29,846,112
D000818:Animals; D001794:Blood Pressure; D003924:Diabetes Mellitus, Type 2; D003928:Diabetic Nephropathies; D065130:Endothelin A Receptor Antagonists; D006973:Hypertension; D007668:Kidney; D007678:Kidney Glomerulus; D008297:Male; D051381:Rats; D044022:Receptor, Endothelin A; D017673:Sodium Chloride, Dietary
American journal of physiology. Renal physiology
2,018
D065130:Endothelin A Receptor Antagonists; D044022:Receptor, Endothelin A; D017673:Sodium Chloride, Dietary
Passive immunotherapy of mice bearing Ehrlich ascites tumor expressing human, membrane-bound placental alkaline phosphatase.
The objective of our study was to test if a tumor expressing a transgene coding for a membrane-bound protein is amenable to immunotherapy by antibodies to the same protein. To this end, we have established an Ehrlich ascites tumor (EAT) cell line, EAT-DAP, stably expressing human, membrane-bound placental alkaline phos...
10.1159/000030121
10,754,465
D000469:Alkaline Phosphatase; D000818:Animals; D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D002286:Carcinoma, Ehrlich Tumor; D002455:Cell Division; D002462:Cell Membrane; D002471:Cell Transformation, Neoplastic; D005260:Female; D005455:Fluorescent Antibody Technique; D058851:GPI-Linked Proteins; D018014...
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
2,000
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D058851:GPI-Linked Proteins; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D007527:Isoenzymes; D012261:Ribonucleoproteins; D000469:Alkaline Phosphatase; C019839:alkaline phosphatase, placental
Endometrial angiogenesis: from physiology to pathology.
Numerous factors have been implicated in angiogenesis. This article concentrates on the expression of the major angiogenic factors, namely, vascular endothelial growth factor (VEGF) and the angiopoietins in the human endometrium. Particular emphasis is placed on the expression of the angiopoietins and their physiologic...
10.1196/annals.1335.003
15,731,297
D000230:Adenocarcinoma; D042501:Angiogenic Proteins; D016889:Endometrial Neoplasms; D004717:Endometrium; D005260:Female; D006801:Humans; D009389:Neovascularization, Pathologic; D018919:Neovascularization, Physiologic
Annals of the New York Academy of Sciences
2,004
D042501:Angiogenic Proteins
Genetics and biochemistry of primary congenital glaucoma.
Several observations noted by early investigators supported the supposition that in most cases, congenital glaucoma is determined by genetic factors. The genetic heterogeneity of PCG was confirmed by genetic linkage studies conducted in the 1990s when the authors determined that CYP1B1 is the congenital glaucoma gene a...
10.1016/s0896-1549(03)00062-2
14,740,995
D001189:Aryl Hydrocarbon Hydroxylases; D001669:Biochemical Phenomena; D001671:Biochemistry; D002874:Chromosome Mapping; D065633:Cytochrome P-450 CYP1B1; D005260:Female; D005901:Glaucoma; D006801:Humans; D008297:Male; D008967:Molecular Biology; D010375:Pedigree; D010641:Phenotype
Ophthalmology clinics of North America
2,003
D001189:Aryl Hydrocarbon Hydroxylases; C585496:CYP1B1 protein, human; C585498:Cyp1b1 protein, mouse; D065633:Cytochrome P-450 CYP1B1
[Antitumor immune response to cervix carcinoma in mice induced by HPV16 E6 DNA vaccines].
OBJECTIVE To investigate the effect of HPV16E6 DNA vaccines on inducing the antitumor immune response to cervix carcinoma in vivo. METHODS We prepared pCB/HPV16E6 DNA vaccines to prevent and treat 615 modle mice transplanted E6 + U14 in vivo respectively. Survival and tumor sizes of all mice were recorded and their l...
16,136,994
D000818:Animals; D019496:Cancer Vaccines; D004279:DNA, Viral; D005260:Female; D051379:Mice; D009368:Neoplasm Transplantation; D009856:Oncogene Proteins, Viral; D012097:Repressor Proteins; D013602:T-Lymphocytes, Cytotoxic; D002583:Uterine Cervical Neoplasms; D019444:Vaccines, DNA
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
2,004
D019496:Cancer Vaccines; D004279:DNA, Viral; C068651:E6 protein, Human papillomavirus type 16; D009856:Oncogene Proteins, Viral; D012097:Repressor Proteins; D019444:Vaccines, DNA
Prediction of pathogen growth on iceberg lettuce under real temperature history during distribution from farm to table.
The growth of pathogenic bacteria Escherichia coli O157:H7, Salmonella spp., and Listeria monocytogenes on iceberg lettuce under constant and fluctuating temperatures was modelled in order to estimate the microbial safety of this vegetable during distribution from the farm to the table. Firstly, we examined pathogen gr...
10.1016/j.ijfoodmicro.2005.02.012
15,979,180
D015169:Colony Count, Microbial; D019453:Escherichia coli O157; D005511:Food Handling; D005516:Food Microbiology; D006920:Hygiene; D007700:Kinetics; D018545:Lactuca; D008089:Listeria monocytogenes; D008954:Models, Biological; D011237:Predictive Value of Tests; D012475:Salmonella; D013696:Temperature
International journal of food microbiology
2,005
Virtual angiography for visualization and validation of computational models of aneurysm hemodynamics.
It has recently become possible to simulate aneurysmal blood flow dynamics in a patient-specific manner via the coupling of three-dimensional (3-D) X-ray angiography and cmputational fluid dynamics (CFD). Before such image-based CFD models can be used in a predictive capacity, however, it must be shown that they indeed...
10.1109/TMI.2005.859204
16,350,918
D000465:Algorithms; D001783:Blood Flow Velocity; D001794:Blood Pressure; D002533:Cerebral Angiography; D003196:Computer Graphics; D003198:Computer Simulation; D006801:Humans; D002532:Intracranial Aneurysm; D008955:Models, Cardiovascular; D011856:Radiographic Image Enhancement; D011857:Radiographic Image Interpretation,...
IEEE transactions on medical imaging
2,005
The relationship between transitional motor skills and locomotion.
This study explores whether transitional skills and sitting correlate with locomotion onset. The development of eight infants was followed. Most transitional skills correlated with locomotor skills. Sitting and rolling did not. Transitional skills may resemble the control needed for locomotion more closely than sitting...
25,594,154
D002657:Child Development; D005260:Female; D006801:Humans; D007223:Infant; D008124:Locomotion; D008137:Longitudinal Studies; D008297:Male; D009048:Motor Skills; D011187:Posture; D013223:Statistics as Topic; D016138:Walking
Infant behavior & development
2,015
Adherence to evidence-based therapies after discharge for acute coronary syndromes: an ongoing prospective, observational study.
PURPOSE To determine the rates of patient adherence to key evidence-based therapies at 6 months after hospital discharge for an acute coronary syndrome. METHODS In this nonrandomized, prospective, multinational, multicenter study, adherence to aspirin, beta-blockers, statins, or angiotensin-converting enzyme (ACE) in...
10.1016/j.amjmed.2003.12.041
15,234,641
D000208:Acute Disease; D000319:Adrenergic beta-Antagonists; D000368:Aged; D000369:Aged, 80 and over; D000569:Americas; D000806:Angiotensin-Converting Enzyme Inhibitors; D001241:Aspirin; D044362:Australasia; D003327:Coronary Disease; D005060:Europe; D019317:Evidence-Based Medicine; D005260:Female; D005500:Follow-Up Stud...
The American journal of medicine
2,004
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin
[General patterns of bone atrophy in the absence of a weight load on the skeleton].
The rate of atrophic changes in spongy bones of the weightless man was estimated, using studies of human, dog and rat bones, as well as observations of neurological patients bed-stricken for a long time. Taking into consideration data on the literature on the bone status and mineral balance in real and simulated space ...
6,876,716
D000328:Adult; D000671:Amputation, Surgical; D000818:Animals; D001284:Atrophy; D001862:Bone Resorption; D001842:Bone and Bones; D003645:Death, Sudden; D004285:Dogs; D006801:Humans; D008297:Male; D008875:Middle Aged; D008903:Minerals; D051381:Rats; D013026:Space Flight; D013045:Species Specificity; D013997:Time Factors;...
Kosmicheskaia biologiia i aviakosmicheskaia meditsina
1,983
D008903:Minerals
Antigenic diversity of granulocytic Ehrlichia isolates from humans in Wisconsin and New York and a horse in California.
The agent of human granulocytic ehrlichiosis (HGE), Ehrlichia phagocytophila, and Ehrlichia equi are very similar. HGE is of variable severity. Genetic and antigenic differences among 3 human isolates (Webster, Spooner, and NY-8) and 1 horse isolate (MRK) were evaluated. The 16S rRNA gene sequences were identical in al...
10.1086/516529
9,333,162
D000818:Animals; D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D003429:Cross Reactions; D004269:DNA, Bacterial; D004536:Ehrlichia; D016873:Ehrlichiosis; D006736:Horses; D006801:Humans; D015151:Immunoblotting; D016056:Immunodominant Epitopes; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S; ...
The Journal of infectious diseases
1,997
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D004269:DNA, Bacterial; D016056:Immunodominant Epitopes; D012336:RNA, Ribosomal, 16S
Distinct modes of channel gating underlie inactivation of somatic K+ current in rat hippocampal pyramidal cells in vitro.
1. We have used the cell-attached configuration of the patch-clamp recording method to characterize the biophysical properties of the voltage-gated K+ channel underlying a 4-aminopyridine (4-AP)- and tetraethylammonium (TEA)-sensitive K+ current (IK(AT)) in pyramidal cells of hippocampal slice cultures. 2. The unitary ...
10.1113/jphysiol.1996.sp021601
8,887,751
D015761:4-Aminopyridine; D000818:Animals; D002462:Cell Membrane; D046508:Culture Techniques; D004594:Electrophysiology; D006624:Hippocampus; D015640:Ion Channel Gating; D007700:Kinetics; D008564:Membrane Potentials; D018408:Patch-Clamp Techniques; D015221:Potassium Channels; D017966:Pyramidal Cells; D051381:Rats; D0137...
The Journal of physiology
1,996
D015221:Potassium Channels; D013757:Tetraethylammonium Compounds; D015761:4-Aminopyridine
The relationship of nutritional copper to the development of postmenopausal osteoporosis in rats.
Factors that influence tissue copper concentration include age, diet, hormones, and pregnancy. In this study we altered diet independently, hormone (estrogen) independently, and various combinations of diet and hormone in animals of the same age to study the effects of ovariectomy complicated with dietary copper defici...
10.1007/BF02789074
7,626,367
D000818:Animals; D015519:Bone Density; D001851:Bone Diseases, Metabolic; D002118:Calcium; D003300:Copper; D004032:Diet; D004195:Disease Models, Animal; D004958:Estradiol; D005260:Female; D005269:Femur; D006801:Humans; D015663:Osteoporosis, Postmenopausal; D010052:Ovariectomy; D010758:Phosphorus; D011897:Random Allocati...
Biological trace element research
1,995
D010758:Phosphorus; D004958:Estradiol; D003300:Copper; D002118:Calcium
How is cervical cancer screening information communicated in UK websites? Cross-sectional analysis of content and quantitative presentation formats.
OBJECTIVES To investigate whether UK websites about cervical cancer screening targeted to the public include (1) information about benefits and risks of screening, possible screening results and cervical cancer statistics, (2) quantitative presentation formats recommended in the risk communication literature and (3) ap...
10.1136/bmjopen-2019-029551
31,662,361
D003142:Communication; D054626:Consumer Health Information; D003430:Cross-Sectional Studies; D003657:Decision Making; D055088:Early Detection of Cancer; D055317:Evidence-Based Practice; D005260:Female; D006801:Humans; D020407:Internet; D012306:Risk; D006113:United Kingdom; D002583:Uterine Cervical Neoplasms
BMJ open
2,019
[2018 world new classification of periodontal and peri-implant diseases and conditions].
World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions was held in Chicago on November 9 to 11, 2017. More than one hundred experts from all over the world attended the conference and updated the 1999 classification of periodontal diseases and conditions, and developed a similar sc...
10.3760/cma.j.issn.1002-0098.2019.02.001
30,695,907
D006801:Humans; D010510:Periodontal Diseases; D010517:Periodontics
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
2,019
Respiratory activity of Ehrlich ascites tumour cell nuclei.
1. Intact Ehrlich ascites tumour cells exhibit a residual respiration which is insensitive to site-specific inhibitors of mitochrondrial electron transport. Treatment of the tumour-bearing mice with phenobarbital does not influence the rate of this inhibitor-resistant respiration. 2. Among the respiratory pigments anal...
10.1007/BF00304092
167,532
D000632:Aminopyrine; D000818:Animals; D000968:Antimycin A; D002286:Carcinoma, Ehrlich Tumor; D002467:Cell Nucleus; D003579:Cytochrome Reductases; D003580:Cytochromes; D004579:Electron Transport; D004721:Endoplasmic Reticulum; D004790:Enzyme Induction; D051379:Mice; D008861:Microsomes; D008928:Mitochondria; D009243:NAD;...
Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology
1,975
D003580:Cytochromes; D000632:Aminopyrine; D012402:Rotenone; D009243:NAD; D000968:Antimycin A; D003579:Cytochrome Reductases; D010634:Phenobarbital
Effect of coexistent scaphotrapezoidal osteoarthrosis on outcome after trapeziectomy.
Scaphotrapezoidal osteoarthrosis can cause persistent pain after trapeziectomy. It has previously been recommended that the scaphotrapezoidal joint should be resected at the time of trapeziectomy to avoid this complication if radiographs show evidence of joint degeneration. We have reviewed the records of 77 patients w...
10.1080/02844310310006440
15,074,722
D002348:Carpal Bones; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures; D010003:Osteoarthritis; D016896:Treatment Outcome; D014955:Wrist Joint
Scandinavian journal of plastic and reconstructive surgery and hand surgery
2,004
Water clusters adsorbed on polycyclic aromatic hydrocarbons: energetics and conformational dynamics.
In this work, we present some classical molecular dynamics (MD) simulations and finite temperature infrared (IR) spectra of water clusters adsorbed on coronene (C24H12), a compact polycyclic aromatic hydrocarbon (PAH). The potential energy surface is obtained within the self-consistent-charge density-functional based t...
10.1063/1.4805015
23,697,420
D000327:Adsorption; D008968:Molecular Conformation; D056004:Molecular Dynamics Simulation; D011083:Polycyclic Compounds; D013499:Surface Properties; D014867:Water
The Journal of chemical physics
2,013
D011083:Polycyclic Compounds; D014867:Water; C012256:coronene
[Female condom or male condom: offer a choice!].
OBJECTIVES As in the entire Ile-de-France, the Val-de-Marne is facing an increase in female contamination by HIV, a clear increase in STI and furthermore the number of legal abortions is still high. Various recent studies have emphasized the decrease in condom use since 1998. Can the possibility of proposing another co...
10.1016/j.gyobfe.2005.09.009
16,243,566
D000163:Acquired Immunodeficiency Syndrome; D000328:Adult; D003075:Coitus; D017280:Condoms; D019111:Condoms, Female; D003258:Consumer Behavior; D005260:Female; D006801:Humans; D008297:Male
Gynecologie, obstetrique & fertilite
2,005
Saucerneol attenuates nasopharyngeal carcinoma cells proliferation and metastasis through selectively targeting Grp94.
BACKGROUND Nasopharyngeal carcinoma (NPC) is highly prevalent in southern China. The remote metastasis of advanced NPC requires chemotherapeutic treatments to reduce the mortality. Our previous work revealed that saucerneol (SN) showed cytotoxicity against several nasopharyngeal carcinoma (NPC) cells. This work aims to...
10.1016/j.phymed.2022.154133
35,504,052
D000818:Animals; D045744:Cell Line, Tumor; D002465:Cell Movement; D049109:Cell Proliferation; D005663:Furans; D015972:Gene Expression Regulation, Neoplastic; D018840:HSP70 Heat-Shock Proteins; D006801:Humans; D017705:Lignans; D008565:Membrane Proteins; D051379:Mice; D008819:Mice, Nude; D000077274:Nasopharyngeal Carcino...
Phytomedicine : international journal of phytotherapy and phytopharmacology
2,022
D005663:Furans; D018840:HSP70 Heat-Shock Proteins; D017705:Lignans; D008565:Membrane Proteins; C018551:glucose-regulated proteins; D051057:Proto-Oncogene Proteins c-akt; D058570:TOR Serine-Threonine Kinases