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22850870 | Microembolization and myonecrosis during elective percutaneous coronary interventions in diabetic patients: an intracoronary Doppler ultrasound study with 2-year clinical follow-up. | Elevation of cardiac troponin I (cTnI) is a well-known complication after percutaneous coronary interventions (PCI). The aims of this study were to quantify the extent of coronary microembolization during elective PCI, to identify predisposing anatomical and procedural factors, and to evaluate its impact on long-term o... | [
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"Coronary Artery Disease",
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17931889 | Combining fMRI and DTI: a framework for exploring the limits of fMRI-guided DTI fiber tracking and for verifying DTI-based fiber tractography results. | A powerful, non-invasive technique for estimating and visualizing white matter tracts in the human brain in vivo is white matter fiber tractography that uses magnetic resonance diffusion tensor imaging. The success of this method depends strongly on the capability of the applied tracking algorithm and the quality of th... | [
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16398129 | Exposure-related effects on Cd bioaccumulation explain toxicity of Cd-phenanthrene mixtures in Hyalella azteca. | Little is known regarding mixture effects of metals and polynuclear aromatic hydrocarbon (PAHs) under environmentally relevant exposure regimes. Standard U.S. Environmental Protection Agency (U.S. EPA) procedures were applied and extended to test effects of phenanthrene (Phen) on sediment-Cd uptake, aqueous-Cd uptake, ... | [
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10232586 | Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors. | A genetically engineered, nonneurotropic herpes simplex virus (R7020) with a proven safety profile in both animals and humans was found effective in the treatment of large xenotransplanted tumors arising from a radiation- and chemotherapy-resistant human epidermoid carcinoma and a hormone-refractory prostate adenocarci... | [
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15842410 | Rare complication of Q fever vaccination. | A 32-year-old woman with a past history of malignant melanoma presented with a lump in the upper left arm that was excised. Histological examination revealed a granulomatous dermatitis and panniculitis that proved to be a rare reaction to Q fever vaccination. | [
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28193299 | Otolaryngology outreach to Komfo Anokye Teaching Hospital: a medical and educational partnership. | BACKGROUND: Medical and educational partnerships between high- and low-resourced countries provide opportunities to have a long-term meaningful impact on medical training and healthcare delivery.METHODS: An otolaryngology partnership between Komfo Anokye Teaching Hospital in Kumasi, Ghana, and the University of Michiga... | [
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10769523 | The effect of grandmultiparity on pregnancy related complications: the Aga Khan University experience. | BACKGROUND: Grandmultiparity has been associated with complications for both mother and the fetus.OBJECTIVE: To evaluate if grandmultiparity is a risk factor in the presence of adequate antenatal care.SETTING: A tertiary care teaching hospital.METHODS: It was a retrospective study conducted in the department of Obstetr... | [
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9232445 | Fc gamma receptor type IIb induced recruitment of inositol and protein phosphatases to the signal transductory complex of human B-cell. | Co-clustering of Fc gamma RIIb and B-cell receptor (BCR) inhibits cell activation by interrupting BCR stimulated signal transduction. The immunoreceptor tyrosine-based inhibitory motif (ITIM) of Fc gamma RIIb becomes tyrosyl phosphorylated (P-ITIM) upon co-clustering with BCR then P-ITIM interacts with several signalli... | [
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14686045 | [Dialectic of the daily life of patients with chronic kidney failure: the unavoidable and the casual]. | The objective of this study was to understand the social reality of patients' daily life with chronic renal failure in hemodialysis. To understand this phenomenon from the theoretical-methodological referential of the historic and dialectic materialism. The interviews were performed with 18 patients submitted to analys... | [
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6628016 | Treatment of atypical mycobacterial disease. | The most common disease patterns produced by atypical mycobacteria are pulmonary disease, cervical lymphadenitis, and infection of soft tissue, bones, and joints. The treatment of disease due to atypical mycobacteria can be confusing unless one clearly differentiates the organisms according to clinical characteristics ... | [
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15522319 | Perioperative diagnosis of cystosarcoma phyllodes of the breast may be enhanced by MIB-1 index. | BACKGROUND: The recurring theme in cystosarcoma phyllodes (CSP) is one of underdiagnosis by pathologists and undertreatment by surgeons. Major areas of investigation relating to the diagnosis of CSP center on accurate preoperative diagnosis, elucidating the relevance of histological classification with respect to outco... | [
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28810065 | Olodaterol shows anti-fibrotic efficacy in in vitro and in vivo models of pulmonary fibrosis. | BACKGROUND AND PURPOSE: Idiopathic pulmonary fibrosis (IPF) is a fatal respiratory disease characterized by excessive fibroblast activation ultimately leading to scarring of the lungs. Although, the activation of â2 -adrenoceptors (â2 -AR) has been shown to inhibit pro-fibrotic events primarily in cell lines, the role ... | [
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26686941 | Cost-effectiveness of culture-guided antimicrobial prophylaxis for the prevention of infections after prostate biopsy. | BACKGROUND: Clinical findings suggest that the use of rectal culture-guided antibiotic prophylaxis reduces the infection rate following transrectal ultrasound-guided prostate biopsy (TRUSBx).METHODS: A decision-analytic model was designed to compare the outcomes of TRUSBx performed with (rectal culture-guided group) an... | [
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17643694 | Intraobserver and interobserver consistency for grading esophagitis with narrow-band imaging. | BACKGROUND: Narrow-band imaging (NBI) is a novel, noninvasive optical technique that adjusts reflected light to enhance the contrast between the esophageal mucosa and the gastric mucosa. Whether the use of this optical technique may increase consistency in describing the presence and severity of mucosal breaks remains ... | [
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9268280 | When authorship fails. A proposal to make contributors accountable. | A published article is the primary means whereby new work is communicated, priority is established, and academic promotion is determined. Publication depends on trust and requires that authors be held to standards of honesty, completeness, and fairness in their reporting, and to accountability for their statements. The... | [
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29325140 | Optimism for the Future in Younger and Older Adults. | OBJECTIVES: Research has suggested that older adults are less optimistic about their future than younger adults; however, a limitation of prior studies is that younger and older adults were forecasting to different ages and stages of life. To address this, we investigated whether there are age differences in future opt... | [
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"Aging",
"Female",
"Forecasting",
"Human Development",
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24335790 | Can district nurses and care home staff improve bowel care for older people using a clinical benchmarking tool? | A quasi-experimental study tested a clinical benchmarking tool (Essence of Care) to improve bowel-related care for older people living in six care homes. In the intervention care homes, district nurses and care home staff used the clinical benchmarking tool to discuss and plan how to improve bowel care for residents. I... | [
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12538670 | Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes. | The MHC class II (MHC-II) transactivator (CIITA) is the master transcriptional regulator of genes involved in MHC-II-restricted Ag presentation. Fine tuning of CIITA gene expression determines the cell type-specific expression of MHC-II genes. This regulation is achieved by the selective usage of multiple CIITA promote... | [
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19357791 | The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury. | Commensal flora and pathogenic microbes influence the incidence of diabetes in animal models yet little is known about the mechanistic basis of these interactions. We hypothesized that Myd88, an adaptor molecule in the Toll-like-receptor (TLR) pathway, regulates pancreatic beta-cell function and homeostasis. We first e... | [
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16715703 | [Poorly-differentiated thyroid carcinoma: morphological verification and differential diagnosis]. | Poorly-differentiated thyroid carcinoma is a stage in the development of anaplastic carcinoma from well-differentiated neoplastic transformation of follicular epithelium. Such tumors differ with respect to histological pattern and age. For instance, patients, aged 50 and more, revealed great nodular size (50-70 mm), ma... | [
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24647335 | Role of vitamin D in children with hepatosteatosis. | BACKGROUND: The increasing incidence of obesity in children is a significant risk factor for nonalcoholic fatty liver disease and obesity-associated morbidity. Vitamin D has a major role in bone mineral metabolism and has antimicrobial, antioxidant properties. In this study we aimed to investigate the role of vitamin D... | [
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24243756 | Internet-based interventions for cancer-related distress: exploring the experiences of those whose needs are not met. | OBJECTIVE: Low levels of engagement in Internet-based interventions are common. Understanding users' experiences with these interventions is a key to improving efficacy. Although qualitative methods are well-suited for this purpose, few qualitative studies have been conducted in this area. In the present study, we asse... | [
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16731653 | Cardiac excitation-contraction coupling is altered in myocytes from aged male mice but not in cells from aged female mice. | This study characterized age-related alterations in excitation-contraction (EC)-coupling in ventricular myocytes and investigated whether these alterations are affected by the sex of the animal. Voltage-clamp experiments were conducted in myocytes from young adult (approximately 7 mo) and aged (approximately 24 mo) mal... | [
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20127972 | Effect of pro-inflammatory and immunoregulatory cytokines on human tenocytes. | Tendon injury induces a local inflammatory response, characterized by the induction of pro-inflammatory cytokines. The aim of the present study was to analyze the effects of TNFalpha, IL-6 and IL-10 on key parameters of tendon homeostasis. Cultured primary human tenocytes were treated with the recombinant cytokines IL-... | [
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24023275 | Effects of surface reflectance and 3D shape on perceived rotation axis. | Surface specularity distorts the optic flow generated by a moving object in a way that provides important cues for identifying surface material properties (Doerschner, Fleming et al., 2011). Here we show that specular flow can also affect the perceived rotation axis of objects. In three experiments, we investigate how ... | [
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8903662 | Hydrochlorothiazide exerts no direct vasoactivity in the human forearm. | BACKGROUND: Recently, hydrochlorothiazide has been shown to relax vascular smooth muscle in vitro in clinically relevant concentrations by the opening of calcium-activated potassium channels, leading to hyperpolarization and consequent closing of voltage-operated calcium channels. Long-term administration of hydrochlor... | [
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29339460 | Dot/Icm-Translocated Proteins Important for Biogenesis of the Coxiella burnetii-Containing Vacuole Identified by Screening of an Effector Mutant Sublibrary. | Coxiella burnetii is an intracellular pathogen that replicates in a lysosome-derived vacuole. A determinant necessary for C. burnetii virulence is the Dot/Icm type IVB secretion system (T4SS). The Dot/Icm system delivers more than 100 proteins, called type IV effectors (T4Es), across the vacuolar membrane into the host... | [
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31307416 | Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection. | BACKGROUND: Cell-surface mucins are expressed in apical epithelial cells of the respiratory tract, and contribute a crucial part of the innate immune system. Despite anti-inflammatory or antiviral functions being revealed for certain cell-surface mucins such as MUC1, the roles of other mucins are still poorly understoo... | [
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19424726 | Drosophila P transposons of the urochordata Ciona intestinalis. | P transposons belong to the eukaryotic DNA transposons, which are transposed by a cut and paste mechanism using a P-element-coded transposase. They have been detected in Drosophila, and reside as single copies and stable homologous sequences in many vertebrate species. We present the P elements Pcin1, Pcin2 and Pcin3 f... | [
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"Sequence Homology, Amino Acid",
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15270886 | Immunohistochemical staining of cutaneous tumours with G-81, a monoclonal antibody to dermcidin. | BACKGROUND: Recently, the novel antimicrobial peptide named dermcidin (DCD) was reported in human eccrine sweat glands.OBJECTIVES: We investigated the expression of DCD in a variety of cutaneous tumours in order to assess the usefulness of the monoclonal antibody (G-81), which recognizes a fragment of DCD.PATIENTS/METH... | [
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725,
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17154517 | Effects of substitution on 9-(3-bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a dihydropyridine ATP-sensitive potassium channel opener. | Structure-activity relationships were investigated on the tricyclic dihydropyridine (DHP) KATP openers 9-(3-bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4-azacyclopenta[b]naphthalene-1,8-dione (6) and 10-(3-bromo-4-fluorophenyl)-9,10-dihydro-1H,8H-2,7-dioxa-9-azaanthracene-4,5-dione (65). Substitution off the core... | [
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28705593 | Parallel placement of Excluder legs for treatment of type IIIb endoleaks caused by fabric tear after endovascular aneurysm repair. | A total of 576 patients underwent endovascular aneurysm repair using main body devices for treatment of abdominal aortic aneurysms or iliac artery aneurysms. During follow-up, type IIIb endoleaks caused by fabric tear occurred in six patients (1.0% [6/576]). The device used was Zenith (Cook Medical, Bloomington, Ind) i... | [
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4038429 | Soy protein products and heme iron absorption in humans. | Dual radioiron tags were used to measure both heme and nonheme iron absorption simultaneously from meat-containing meals in 76 healthy male volunteers. Partial substitution of beef with soy flour reduced the availability of nonheme iron but improved the percentage absorption of heme iron significantly (27 to 59% rise).... | [
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10107972 | Changes in the healthcare profession: from denial to acceptance. | As the government and other factors seem to be increasingly gaining control over the healthcare industry, many hospital managers and staff feel as if they're increasingly losing control over their jobs and their futures. Indeed, some administrators and physicians are experiencing a kind of stress that may be seen as a ... | [
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8155715 | The kinetic studies on the intramolecular SH, S-S exchange reaction of bovine mercaptalbumin. | Bovine mercaptalbumin (BMA) has 17 disulfide bonds and one SH group at Cys-34 which catalyzes the intramolecular SH, S-S exchange reaction (N-A isomerization, molecular aging) in the alkaline region at low ionic strength, resulting in the formation of the aged form (A-form). The aging reaction was completely reversible... | [
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26784001 | Trends in gynecologic cancer among elderly women in Denmark, 1980-2012. | BACKGROUND: The aim of this analysis was to describe trends in incidence, mortality, prevalence, and survival in Danish women with gynecologic cancer from 1980-2012 comparing women aged 70 years or more with younger women.MATERIAL AND METHODS: Gynecologic cancers included were ICD-10 codes C53 (cancer of the cervix ute... | [
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26719548 | PARTIAL ANOMALOUS PULMONARY VENOUS CONNECTION WITH INTACT ATRIAL SEPTUM: A CASE REPORT. | Partial anomalous pulmonary venous connection (PAPVC) is a type of left to right shunt, when one or more lung veins drain to right atrium directly or indirectly via systemic veins. PAPVC is a rare condition, discovered by 0.4 to 0.7% of cases in autopsy series. It is often associated with atrial septal defect, but can ... | [
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12627360 | Risk factors for postcraniotomy surgical site infection after 1,3-bis (2-chloroethyl)-1-nitrosourea (Gliadel) wafer placement. | Gliadel wafers (1,3-bis [2-chloroethyl]-1-nitrosourea; Guilford Pharmaceuticals) are approved for the treatment of malignant gliomas; however, the incidence of and risk factors associated with infection with respect to this new technology are unknown. We identified 32 patients who received Gliadel wafers from December ... | [
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19242337 | Norepinephrine increases blood pressure but not survival with anthrax lethal toxin in rats. | OBJECTIVES: The response of anthrax lethal toxin (LeTx) induced shock and lethality to conventional therapies has received little study. Previously, fluids worsened outcome in LeTx-challenged rats in contrast to its benefit with lipopolysaccharide (LPS) or Escherichia coli. The current study investigated norepinephrine... | [
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"Survival Rate",
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16546229 | The relationship between prevalence of active trachoma, water availability and its use in a Tanzanian village. | This study aimed to establish the relationship between the prevalence of active trachoma in children, water availability and household water use in a village in Tanzania. Nine hundred and fourteen children aged 1-9 years were examined for signs of trachoma. Data were collected on time taken to collect water, amount of ... | [
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23865669 | Medicaid family planning expansions and related preventive care. | I examined the impact of state expansions in eligibility for Medicaid family planning services on the utilization of Papanicolaou (Pap) tests, clinical breast examinations, HIV testing, and routine doctor check-ups among women aged 21 to 44 years using the Behavioral Risk Factor Surveillance System (1993-2009). Using a... | [
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"Breast Diseases",
"Family Planning Services",
"Female",
"Humans",
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"Preventive Medicine",
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"Young Adult"
] | {
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443736 | [Calcitonin-cells in the thyroid of the human fetus. Immunocytochemical study (author's transl)]. | Calcitonin (CT)-cells were detected, by using an anti-human calcitonin serum (hCT), in the thyroid of the normal and anencephalic human fetuses. The first CT-cells were observed at 14 weeks of gestation. The CT-cells were at first isolated afterwards were appeared in parafollicular localization. The CT-cells were only ... | [
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682,
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3114,
179
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] | {
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8655422 | Feedlot performance and carcass characteristics of Holstein steers as affected by source of dietary protein and level of ruminally protected lysine and methionine. | The objective of this study was to determine the effects of source of dietary CP and level of ruminally protected lysine and methionine (RPLM) on feedlot performance and carcass characteristics of Holstein steers during a growing-finishing trial (266 d). A total of 168 Holstein steers (182.7 +/- 27.5 kg) were used in a... | [
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4834,
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"Cattle",
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"Food, Fortified",
"Lysine",
"Male",
"Meat",
"Methionine",
"Plant Proteins, Dietary",
"Soybean Proteins",
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] | {
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11310734 | Effect of mutations in Pisum sativum L. genes blocking different stages of nodule development on the expression of late symbiotic genes in Rhizobium leguminosarum bv. viciae. | In this report, the expression of late symbiotic genes (fnrN, fixN, and nifA) of Rhizobium leguminosarum bv. viciae was studied in nodules of mutant pea lines blocked at four successive stages of nodule development. Bacterial gene expression was analyzed in situ with transcriptional gusA reporter gene fusions. As a con... | [
2146,
666,
8158,
15308,
7269
] | [
"Genes, Bacterial",
"Mutation",
"Peas",
"Rhizobium leguminosarum",
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] | {
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28684433 | Wheat Vacuolar Iron Transporter TaVIT2 Transports Fe and Mn and Is Effective for Biofortification. | Increasing the intrinsic nutritional quality of crops, known as biofortification, is viewed as a sustainable approach to alleviate micronutrient deficiencies. In particular, iron deficiency anemia is a major global health issue, but the iron content of staple crops such as wheat (Triticum aestivum) is difficult to chan... | [
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2731,
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"Biofortification",
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"Flour",
"Gene Expression Regulation, Plant",
"Genome, Plant",
"Iron",
"Manganese",
"Membrane Transport Proteins",
"Phenotype",
"Phytic Acid",
"Plant Development",
"Plant Proteins",
"Plants, Genetically Modified",
"Sequence Homolog... | {
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29068324 | Risk factors for acute cholecystitis and for intraoperative complications. | BACKGROUND: Acute cholecystitis is still frequent in emergency surgical departments. As surgical technique, nowadays laparoscopy is widely used and with low complications and with low postoperative morbidity.MATERIAL AND METHODS: We perform an analytical study about the safety of laparoscopic surgery in patients with a... | [
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25700635 | Prevalence and impact of urinary incontinence in men with cystic fibrosis. | OBJECTIVES: To determine the prevalence and impact of urinary incontinence (UI) in men with cystic fibrosis (CF).DESIGN: Prospective observational study.SETTING: Adult CF clinics at tertiary referral centres.PARTICIPANTS: Men with CF (n=80) and age-matched men without lung disease (n=80).INTERVENTIONS: Validated questi... | [
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22822635 | Clinical profile and aetiology of optic neuritis in Hospital Universiti Sains Malaysia--5 years review. | Although few studies concerning optic neuritis (ON) in Asian countries have been reported, there is no report about ON in Malaysia particularly within the Malay population. We aimed to determine the clinical manifestation, visual outcome and aetiology of ON in Malays, and discussed the literature of ON studies in other... | [
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28433513 | Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities. | New microtubule depolymerizing agents with potent cytotoxic activities have been prepared with a 5-cyano or 5-oximino group attached to a pyrrole core. The utilization of ortho activation of a bromopyrrole ester to facilitate successful Suzuki-Miyaura cross-coupling reactions was a key aspect of the synthetic methodolo... | [
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"Neoplasms",
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21906921 | Plasma cytokines, glomerular filtration rate and adipose tissue cytokines gene expression in chronic kidney disease (CKD) patients. | BACKGROUND AND AIM: Systemic inflammation is a hallmark of chronic kidney disease (CKD) and obesity represents a major risk factor for CKD. We investigated the relationship between plasma interleukin-6 (IL-6) and tumour necrosis factor-á (TNF-á) and the glomerular filtration rate (GFR) in 75 stage 2-5 CKD patients.METH... | [
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2145836 | Isolation and expression of cDNA for different forms of hepatocyte growth factor from human leukocyte. | Human leukocyte cDNA library was screened to isolate cDNA clones coding for hepatocyte growth factor using cDNA from human liver as a probe. Nucleotide and deduced amino acid sequences were analyzed for two of four clones obtained. One of them contained an open reading frame coding for a polypeptide chain of 728 amino ... | [
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9278618 | Diagnosis of Enterocytozoon bieneusi (microsporidia) infections by polymerase chain reaction in stool samples using primers based on the region coding for small-subunit ribosomal RNA. | OBJECTIVE: Enterocytozoon bieneusi is the most prevalent microsporidian causing chronic diarrhea in patients with acquired immunodeficiency syndrome. The current methods used for routine diagnosis of infections caused by microsporidia are based on microscopic detection of the microorganism spores in stained smears. We ... | [
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9534367 | Effects of toothbrush design and brushing proficiency on plaque removal. | A single-blind, short-term cross-over clinical trial compared the plaque removal performance of three commercially available manual toothbrushes. A sample of 25 dental hygiene students, 19 to 42 years old, served as participants. On 3 separate occasions, participants were instructed to refrain from toothbrushing or flo... | [
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27779785 | Development and validation of a mathematical equation to estimate glomerular filtration rate in cirrhosis: The royal free hospital cirrhosis glomerular filtration rate. | Current expressions based on serum creatinine concentration overestimate kidney function in cirrhosis, leading to significant differences between "true" and calculated glomerular filtration rate (GFR). We compared the performance of the four-variable and six-variable Modification of Diet in Renal Disease and chronic ki... | [
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5764408 | The effect of cyanide on the efflux of calcium from squid axons. | 1. The average rate constant for loss of (45)Ca from an unpoisoned squid axon was 1.8 x 10(-3) min(-1), corresponding to an efflux of 0.2 p-mole/cm(2) sec.2. The Ca efflux from unpoisoned axons was reduced if external calcium was replaced with magnesium, or external sodium with lithium, choline or dextrose. Replacing b... | [
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25935233 | Translation and cultural adaptation of the Mother-Generated Index into Brazilian Portuguese: A postnatal quality of life study. | OBJECTIVE: quality of life issues are central to maternal health and well-being. Within the context of a study examining postnatal quality of life, we set out to translate into Brazilian Portuguese the Mother-Generated Index and ensure its cross-cultural adaption for use in a Brazilian context.DESIGN: the Mother-Genera... | [
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] | {
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22900828 | Versatile roles of Arabidopsis plastid ribosomal proteins in plant growth and development. | A lack of individual plastid ribosomal proteins (PRPs) can have diverse phenotypic effects in Arabidopsis thaliana, ranging from embryo lethality to compromised vitality, with the latter being associated with photosynthetic lesions and decreases in the expression of plastid proteins. In this study, reverse genetics was... | [
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12923826 | Validation of the Korean version of the Bayer activities of daily living scale. | The Bayer-activities of daily living (B-ADL) is a brief and internationally applicable ADL instrument which has been validated in three European countries. The B-ADL has been developed to provide a tool for the assessment of functional deficits in performance of every day tasks as they are observed in mild to moderate ... | [
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8936183 | Development of a nurse-managed, school-based health center. | As the healthcare environment continues to change, nurses are developing models for interdisciplinary care in a variety of community settings. The high school is an ideal treatment setting for the delivery of health services to adolescents. This article describes the development of a nurse-managed, school-based health ... | [
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8295455 | Cerebrospinal fluid leak following acoustic neuroma removal. | Cerebrospinal fluid (CSF) leak has been a constant and unresolved complication of acoustic tumor surgery. This study retrospectively reviews 381 primary acoustic tumor surgeries performed by a single, senior, neurotologist and neurosurgeon team from 1979 through 1991. There were 68 cerebrospinal fluid leaks in 66 patie... | [
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13840,
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414,
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160,
2913,
695,
598,
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2084280 | A new stereophonic stethoscope. | A new stereophonic stethoscope is presented. It is characterized by a single chest piece construction housing paired open-bell type sound accumulating chambers and paired diaphragm type sound accumulating chambers. A pair of separate ear tubes connected to each of the paired sound chambers establish two cross talk-free... | [
88,
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"Humans"
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} |
25028013 | Differential cross sections for intermediate-energy electron scattering from á-tetrahydrofurfuryl alcohol: excitation of electronic-states. | We report on measurements of differential cross sections (DCSs) for electron impact excitation of a series of Rydberg electronic-states in á-tetrahydrofurfuryl alcohol (THFA). The energy range of these experiments was 20-50 eV, while the scattered electron was detected in the 10°-90° angular range. There are currently ... | [
9290,
2089,
11424,
5637,
834
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"Furans",
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} |
29933998 | Baseline sensitivity and biochemical responses of Valsa mali to propamidine. | In the current study, baseline sensitivity of Valsa mali to propamidine was determined using 80 strains collected from apple orchards in Shaanxi Province, China. The median effective concentration (EC50) values for propamidine inhibiting mycelial growth ranged from 0.086 to 0.852 ìg/mL, with a mean of 0.405 ± 0.137 ìg/... | [
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"Mitochondria",
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17433797 | Video-capsule endoscopy gastric and small bowel transit time and completeness of the examination in patients with diabetes mellitus. | BACKGROUND: Small intestine video-capsule endoscopy examination in patients with diabetes mellitus may be incomplete due to delayed gastric emptying.AIM: To measure video-capsule endoscopy gastric and small bowel transit time and to assess the completeness of the examination in diabetes mellitus patients.METHODS: In th... | [
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3474,
3,
2079,
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"Male",
"Middle Aged",
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] | {
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} |
8699828 | Dorsal laminectomy in the adult mouse: a model for nervous system research. | Animal strains with specific genetic mutations can serve as powerful tools to study normal and pathologic cellular and molecular processes. The mammalian species with the largest number of known genetic mutations is the mouse. In spinal cord research, mice have not been used as extensively as other species because of t... | [
30,
613,
2350,
35,
36,
8730,
2185,
2553
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"Male",
"Mice",
"Mice, SCID",
"Spinal Cord",
"Spinal Cord Injuries"
] | {
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} |
4059887 | Simulation of paretic gait in normal subjects by loading the ankles. | Normal subjects were loaded with increasing weights (2-6 kg) applied around the ankles. During these conditions stride length increased in relation to velocity. The percentage duration of single support in relation to stride duration increased. Provided the same load was applied around both ankles increase was symmetri... | [
204,
9,
2535,
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3950,
3,
890,
35,
160,
120
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"Adult",
"Ankle",
"Female",
"Gait",
"Humans",
"Leg",
"Male",
"Middle Aged",
"Muscles"
] | {
"A": 1,
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} |
26305457 | Body Condition Indices Predict Reproductive Success but Not Survival in a Sedentary, Tropical Bird. | Body condition may predict individual fitness because those in better condition have more resources to allocate towards improving their fitness. However, the hypothesis that condition indices are meaningful proxies for fitness has been questioned. Here, we ask if intraspecific variation in condition indices predicts an... | [
30,
1372,
1718,
7191,
16280,
11815,
1179,
502,
4034,
23,
4695
] | [
"Animals",
"Blood Proteins",
"Body Size",
"Fats",
"Finches",
"Genetic Fitness",
"Hemoglobins",
"Muscle Proteins",
"Reproduction",
"Seasons",
"Sexual Behavior, Animal"
] | {
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22046406 | Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese. | BACKGROUND: Several novel susceptibility loci for type 2 diabetes have been identified through genome-wide association studies (GWAS) for type 2 diabetes or quantitative traits related to glucose metabolism in European populations. To investigate the association of the 13 new European GWAS-derived susceptibility loci w... | [
761,
1778,
218,
1880,
1919,
3,
2022,
634
] | [
"Case-Control Studies",
"Diabetes Mellitus, Type 2",
"European Continental Ancestry Group",
"Genetic Predisposition to Disease",
"Genome-Wide Association Study",
"Humans",
"Japan",
"Polymorphism, Single Nucleotide"
] | {
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} |
15247917 | Evidence for nucleosome depletion at active regulatory regions genome-wide. | The identification of nuclease-hypersensitive sites in an active globin gene and in the 5' regions of fruit fly heat shock genes first suggested that chromatin changes accompany gene regulation in vivo. Here we present evidence that the basic repeating units of eukaryotic chromatin, nucleosomes, are depleted from activ... | [
5337,
2789,
4732,
3908,
3371,
1174
] | [
"Genes, Fungal",
"Histones",
"Nucleosomes",
"Regulatory Sequences, Nucleic Acid",
"Saccharomyces cerevisiae",
"Transcription, Genetic"
] | {
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23798911 | Focal neuropathies following percutaneous nephrolithotomy (PCNL)--preliminary study. | INTRODUCTION: Postoperative neurological complications in pelvic and renal surgery are a well-known clinical problem and their morbidities are important. We designed this study to determine prevalence and risk factors of such complications after percutaneous nephrolithotomy (PCNL) surgery.MATERIAL AND METHODS: A cross-... | [
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28644574 | Effect of an impaired oral stage on swallowing in patients with Parkinson's disease. | We investigated the swallowing function in patients with Parkinson's disease (PD) using deteriorated tongue control because patients with PD frequently exhibit an impaired oral stage of swallowing and the tongue movement affects oral and pharyngeal stage. In total, 201 patients with PD (106 men, 95 women; mean age 70·6... | [
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16221204 | Curcumin blocks fibrosis in anti-Thy 1 glomerulonephritis through up-regulation of heme oxygenase 1. | BACKGROUND: Induction of heme oxygenase 1 (HO-1) has been shown to be beneficial in a variety of pathologic settings. Curcumin, a polyphenolic compound, has antifibrotic effects in lung models of fibrosis, and is known to induce HO-1 in renal tubular cells. In this study, we determined whether curcumin has antifibrotic... | [
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28530182 | Green synthesis of highly stable carbon nanodots and their photocatalytic performance. | The present study reports a novel, facile, biosynthesis route for the synthesis of carbon nanodots (CDs) with an approximate quantum yield of 38.5%, using Musk melon extract as a naturally derived-precursor material. The synthesis of CDs was established by using ultraviolet-visible (UV-vis) spectroscopy, Dynamic light ... | [
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25801077 | A tomato chloroplast-targeted DnaJ protein protects Rubisco activity under heat stress. | Photosynthesis is one of the biological processes most sensitive to heat stress in plants. Carbon assimilation, which depends on ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), is one of the major sites sensitive to heat stress in photosynthesis. In this study, the roles of a tomato (Solanum lycopersicum) ch... | [
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3836513 | Indoor air pollution due to tobacco smoke under real conditions. Preliminary results. | A short review exploring the generation and composition of tobacco smoke is given. Experimental arrangements used to record sidestream smoke are critically discussed. Data from own experiments in a tobacco smoke polluted office room were presented and discussed. These data include nicotine, ammonia, formaldehyde, aceta... | [
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30545725 | Write a Scientific Paper (WASP) - What can I publish [1]? Types of studies. | As an experienced writer, one is often asked the question "what can I publish" by younger and inexperienced colleagues who must publish. This paper will briefly review the reasons why academics publish and will then outline what kind of papers one may be able to publish with relative ease, using personal experience and... | [
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25189954 | Value of knee skin temperature measured by infrared thermography and soluble intercellular adhesion molecule-1 in the diagnosis of peri-prosthetic knee infection in Chinese individuals following total knee arthroplasty. | BACKGROUND: Total knee arthroplasty (TKA) is a successful and frequently performed procedure in orthopedic surgery. The diagnosis of peri-prosthetic joint infection following TKA remains challenging. The present study estimated the usefulness of knee skin temperature (measured by infrared thermography) and serum solubl... | [
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19210256 | Assessment of laboratory and biosafety practices associated with bacterial culture in veterinary clinics. | OBJECTIVE: To investigate bacterial culture practices in veterinary clinics, with an emphasis on laboratory biosafety and on quality of laboratory practices.DESIGN: Survey-based prospective study.SAMPLE POPULATION: 166 veterinarians.PROCEDURES: Veterinarians were recruited through the Veterinary Information Network (an... | [
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17964945 | Methods and applications of site-directed spin labeling EPR spectroscopy. | Site-directed spin labeling (SDSL) electron paramagnetic resonance (EPR) spectroscopy has emerged as a well-established method that can provide specific information on the location and environment of an individual residue within large and complex protein structures. The SDSL technique involves introducing a cysteine re... | [
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18619752 | Assessment of regional left ventricular function by dual source computed tomography: interobserver variability and validation to laevocardiography. | OBJECTIVE: Assessment of left ventricular function is possible in contrast-enhanced cardiac CT data sets. However, rapid ventricular motion especially in systole can lead to artifacts. Dual Source Computed Tomography (DSCT) has high temporal resolution which effectively limits motion artifact. We therefore assessed the... | [
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19398645 | Effects of cranberry juice on pharmacokinetics of beta-lactam antibiotics following oral administration. | Cranberry juice consumption is often recommended along with low-dose oral antibiotics for prophylaxis for recurrent urinary tract infection (UTI). Because multiple membrane transporters are involved in the intestinal absorption and renal excretion of beta-lactam antibiotics, we evaluated the potential risk of pharmacok... | [
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21307125 | p53 target Siva regulates apoptosis in ischemic kidneys. | The role of p53 in inducing apoptosis following acute kidney injury is well-established; however, the molecular mechanisms remain largely unknown. We report here that the p53 proapoptotic target Siva and its receptor CD27, a member of the tumor necrosis factor receptor family, are upregulated following renal ischemia-r... | [
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10765890 | Opinions and feelings on eating with complete dentures: a qualitative inquiry. | Our knowledge of variables affecting the coping strategies that lead to acceptance of foods in populations wearing complete dentures is limited. Focus groups were conducted with the specific aim of determining factors responsible for successful adaptation to chewing with complete dentures. Each of the five focus groups... | [
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18043645 | Biological and chemical sulfide oxidation in a Beggiatoa inhabited marine sediment. | The ecological niche of nitrate-storing Beggiatoa, and their contribution to the removal of sulfide were investigated in coastal sediment. With microsensors a clear suboxic zone of 2-10 cm thick was identified, where neither oxygen nor free sulfide was detectable. In this zone most of the Beggiatoa were found, where th... | [
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9196161 | Phase II randomized trial of gallium nitrate plus fluorouracil versus methotrexate, vinblastine, doxorubicin, and cisplatin in patients with advanced transitional-cell carcinoma. | PURPOSE: A phase II randomized trial of gallium nitrate/fluorouracil (5-FU) versus dose-intense methotrexate, vinblastine, doxorubicin, and cisplatin (M-VAC) was performed in poor-risk patients with advanced urothelial tract tumors. The efficacy and toxicity of these regimens were compared. Assessment of dose-intense M... | [
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6270167 | Differences in oxygen-dependent regulation of enzymes between tumor and normal cell systems in culture. | Metabolic studies in tumor cells have indicated that bioenergetic regulatory mechanisms geared to acute changes in oxygen availability are abnormal. In the present studies we have examined bioenergetic adaptations to chronic oxygen depletion in culture maintained tumor cells in comparison to normal cell lines. Activiti... | [
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16410973 | The feature of papers and citation analysis of eleven journals in tropical medicine indexed by Science Citation Index Expanded. | To determine the features of papers, authors, and citation of eleven journals in tropical medicine indexed by Science Citation Index Expanded, the database of the Institute for Scientific Information, we analyzed original articles, editorials, reviews, corrections, letters, biographies, and news published in these jour... | [
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570924 | Stereotypic and hypothermic effects of apomorphine and N-n-propylnorapomorphine in mice. | Two dopaminergic agonists, apomorphine (APO) and N-n-propylnorapomorphine (NPA) were compared in mice for their ability to induce stereotypic cage-climbing and hypothermia. Stereotypic cage-climbing responses were recorded on videotape and subsequently rated "blind" in comparison to the animal's predrug behavior and to... | [
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2576269 | Analysis of benzodiazepines and tricyclic antidepressants in serum using a common solid-phase clean-up and a common mobile phase. | A single, rapid and specific solid-phase clean-up procedure was developed for the analysis of benzodiazepines and tricyclic antidepressants using a carefully selected wash step and specific sequential elution. Benzodiazepines were eluted from the solid-phase column using as mixture of water-methanol-acetonitrile (2:3:3... | [
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1150
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10656726 | Employee competence and performance-based assessment: A college of American pathologists Q-probes study of larboratory personnel in 522 institutions. | OBJECTIVE: To survey employee competence assessment practices in departments of pathology and laboratory medicine and provide suggestions for improvement.DESIGN: A 3-part study consisting of a questionnaire about current competence assessment practices, an evaluation of compliance with stated competence assessment prac... | [
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19929127 | Integrative cognitive-behavioral and spiritual counseling for rural dementia caregivers with depression. | OBJECTIVE: Discuss initial evaluation of a program for training faith community nurses (FCNs) to conduct cognitive-behavioral and spiritual counseling (CBSC) for rural dementia caregivers (CGs), and present 2 case studies on the use of CBSC for treating depression in this population.STUDY DESIGN: Pre-post evaluation of... | [
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2880162 | Effect of indomethacin on arterial oxygenation in critically ill patients with severe bacterial pneumonia. | The effect of indomethacin (1 mg/kg) on gas exchange was studied in ten patients with hypoxaemic respiratory failure precipitated by bacterial pneumonia. Mean arterial oxygen tension (PaO2) improved significantly (79 +/- 16 mm Hg to 98 +/- 20 mm Hg) but the response varied between patients: five showed substantial resp... | [
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30580508 | Ultrasensitive SERS Substrate for Label-Free Therapeutic-Drug Monitoring of Paclitaxel and Cyclophosphamide in Blood Serum. | Surface-enhanced Raman spectroscopy (SERS) has recently emerged as an innovative tool for therapeutic-drug monitoring (TDM), making it an ideal candidate for personalized treatment. Herein, we report a layer-by-layer (LbL) approach for the fabrication of a highly reproducible hybrid SERS substrate based on graphene oxi... | [
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"Drug Monitoring",
"Gold",
"Graphite",
"Humans",
"Metal Nanoparticles",
"Paclitaxel",
"Quinolines",
"Serum Albumin, Bovine",
"Spectrum Analysis, Raman"
] | {
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} |
30858462 | Early life stress delays hippocampal development and diminishes the adult stem cell pool in mice. | Early life stress predisposes to mental illness and behavioral dysfunction in adulthood, but the mechanisms underlying these persistent effects are poorly understood. Stress throughout life impairs the structure and function of the hippocampus, a brain system undergoing considerable development in early life. The long-... | [
30,
72,
11643,
2,
35,
36,
447,
7044,
5408,
966
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"Animals",
"Cell Proliferation",
"Dentate Gyrus",
"Female",
"Male",
"Mice",
"Mice, Inbred C57BL",
"Neural Stem Cells",
"Neurogenesis",
"Stress, Psychological"
] | {
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} |
23290264 | Apelin-13 increases expression of ATP-binding cassette transporter A1 via activating protein kinase C á signaling in THP-1 macrophage-derived foam cells. | Apelin has an antiatherogenic function through activating protein kinase C (PKC) to initiate a series of cellular signaling pathways. PKC phosphorylates and stabilizes ATP-binding cassette transporter A1 (ABCA1) through inhibiting its degradation mediated by calpain. Thus, in the present study, we investigated whether ... | [
8012,
3490,
10322,
657,
1085,
10929,
3,
3550,
1357,
3297
] | [
"ATP Binding Cassette Transporter 1",
"ATP-Binding Cassette Transporters",
"Calpain",
"Cell Line",
"Cholesterol",
"Foam Cells",
"Humans",
"Intercellular Signaling Peptides and Proteins",
"Macrophages",
"Protein Kinase C-alpha"
] | {
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} |
12950678 | Histamine inhibits neutrophil NADPH oxidase activity triggered by the lipoxin A4 receptor-specific peptide agonist Trp-Lys-Tyr-Met-Val-Met. | The vasoactive amine histamine is found at high concentrations in the immune and inflammatory tissues. Earlier studies have revealed that histamine regulates the nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase-dependent formation of oxygen radicals by phagocytic cells. However, the effects of histamine on i... | [
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20590,
588,
366,
1508
] | [
"Chemotactic Factors",
"Cytoplasmic Granules",
"Down-Regulation",
"Enzyme Inhibitors",
"Histamine",
"Humans",
"N-Formylmethionine Leucyl-Phenylalanine",
"NADPH Oxidases",
"Neutrophils",
"Oligopeptides",
"Receptors, Cell Surface",
"Receptors, Formyl Peptide",
"Receptors, Lipoxin",
"Signal T... | {
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} |
6378210 | NuMA protein is a human autoantigen. | Routine examination of sera from patients with suspected or confirmed connective tissue disease has revealed the presence of autoantibodies directed against an unusual nuclear antigen. As characterized by immunofluorescence studies, the antigen is found exclusively in the nuclei of interphase cells, but appears to be p... | [
3708,
622,
3709,
775,
2065,
3,
4644,
1532,
717,
9573
] | [
"Antibodies",
"Antibodies, Monoclonal",
"Antigens",
"Autoantigens",
"Fluorescent Antibody Technique",
"Humans",
"Immunologic Techniques",
"Molecular Weight",
"Peptide Fragments",
"Spindle Apparatus"
] | {
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} |
16879847 | Two separate outbreaks of Salmonella enteritidis phage type 14b food poisoning linked to the consumption of the same type of frozen food. | OBJECTIVES: To ascertain, using a combination of epidemiological, environmental and microbiological methods of investigation, a possible link between two outbreaks of salmonella food poisoning.METHODS: Case-control studies were carried out on the known at-risk populations. Environmental investigations took place in the... | [
9,
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310,
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761,
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"Adult",
"Aged",
"Aged, 80 and over",
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"Case-Control Studies",
"Cooking",
"Disease Outbreaks",
"Eggs",
"Electrophoresis, Gel, Pulsed-Field",
"Female",
"Frozen Foods",
"Humans",
"Male",
"Middle Aged",
"Restaurants",
"Salmonella Food Poisoning",
"Salmonella enter... | {
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19162635 | Temperature-dependent dielectric properties of liver tissue measured during thermal ablation: toward an improved numerical model. | The development of microwave tumor ablation devices depends largely on numerical simulations of antenna characteristics and transient electromagnetic heating. However, without an adequate tissue model simulation predictions can vary widely from experimental results. In this study, tissue dielectric properties are measu... | [
30,
2183,
1541,
1120,
4225,
34,
427,
3152,
1542,
1890,
572
] | [
"Animals",
"Body Temperature",
"Computer Simulation",
"Electric Impedance",
"Hyperthermia, Induced",
"In Vitro Techniques",
"Liver",
"Microwaves",
"Models, Biological",
"Surgery, Computer-Assisted",
"Swine"
] | {
"A": 1,
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} |
32005472 | Three-dimensional changes of the upper airway in patients with Class II malocclusion treated with the Herbst appliance: A cone-beam computed tomography study. | INTRODUCTION: This study aimed to determine the volumetric effects on the upper airways of growing patients with Class II malocclusion treated with the Herbst appliance (HA).METHODS: Volumetric measurements of the upper airways of 42 skeletal Class II malocclusion patients (mean age: 13.8 ± 1.2 years; ranging from 12.0... | [
204,
6154,
104,
4509,
3,
5102,
172,
14066,
8794,
7034
] | [
"Adolescent",
"Cephalometry",
"Child",
"Cone-Beam Computed Tomography",
"Humans",
"Malocclusion, Angle Class II",
"Mandible",
"Mandibular Advancement",
"Oropharynx",
"Orthodontic Appliances, Functional"
] | {
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} |
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