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Specificity was highest for the Athens CIN Score (Lazaros, ###), and this was accompanied with a positive predictive value of ##% and a negative predictive value of ##% Highest reported specificity of the <PERSOON> score was ##% (Aykan, ###) Specificity of the simple risk score of <PERSOON> (###) was found to be ##% ... | 657 | fms |
have the best value in identification of patients with increased risk of PC-AKI? Which clinical tools or questionnaires have the best diagnostic value in identification of patients with increased P (patient category) adult (â¥## years) patients receiving intravascular iodine-containing contrast medium; I (intervention... | 667 | fms |
fifth sub question, the databases Medline (OVID), Embase and the Cochrane Library were searched from #st of January ### up to ##th of September ### using relevant search terms for systematic reviews (SRs), randomized controlled trials (RCTs) and observational studies (OBS) This search was updated on April ##th , ### ... | 610 | fms |
included in the evidence tables <PERSOON> evidence tables and assessment of individual study quality are included ## studies were included in the literature analysis, the most important study characteristics and results were ## studies were included in the literature analysis, the most important study characteristics... | 615 | fms |
intervention a prospective, multicenter, randomized study to analyze the effect of hydration and acetylcysteine <PERSOON> YL, Fu NK, <PERSOON> J, et al A simple preprocedural score for risk of contrast-induced acute kidney injury after <PERSOON> E, Poh KK, Lu Q, et al Comparison of combination therapy of high-dose ... | 590 | fms |
as a risk factor for contrast-induced <PERSOON> E, et al Contrast-induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables <PERSOON> RH, et al Contrast material-induced nephrotoxicity and intravenous low-osmolality iodinated contrast material risk... | 629 | fms |
et al Risk score for the prediction of contrast-induced nephropathy in elderly patients undergoing <PERSOON> I, et al Contrast induced acute kidney injury in acute coronary syndrome patients A single Gao YM, <PERSOON> D, <PERSOON> H, et al Derivation and validation of a risk score for contrast-induced nephropathy a... | 591 | fms |
<PERSOON> G, et al Impact of female gender on frequency of contrast medium-induced nephropathy post hoc analysis of dialysis versus diuresis trial <PERSOON>) ### <PERSOON> M, et al Association of radial versus femoral access with contrast-induced acute kidney injury in patients undergoing primary percutaneous coro... | 611 | fms |
Risk Score of Contrast-Induced Nephropathy in Elderly Patients Undergoing <PERSOON> YS, Fang HY, <PERSOON> H, et al Predictors of contrast-induced nephropathy in chronic total occlusion percutaneous <PERSOON> WP, Bei WJ, et al A novel risk score model for prediction of contrast-induced nephropathy after emergent <PER... | 666 | fms |
Effects of hydration in contrast-induced acute kidney injury after primary angioplasty a <PERSOON> AL Hemofiltration in the prevention of radiocontrast agent induced nephropathy <PERSOON> EW, et al Posttraumatic contrast-induced acute kidney injury minimal consequences or McDonald JS, Katzberg RW, McDonald RJ, et a... | 609 | fms |
value of the red blood cell distribution width to the <PERSOON> risk score for predicting contrast-induced acute kidney injury in patients with ST-elevation acute myocardial infarction <PERSOON> G, et al Prediction of presence of kidney disease in a general patient population undergoing Nikolsky E, <PERSOON> Z, et al... | 564 | fms |
#<DATUM> <PERSOON> B, <PERSOON> MM, et al Lower blood vitamin D levels are associated with an increased incidence of contrastinduced nephropathy in patients undergoing coronary angiography <PERSOON> K, et al CINC-J study investigators Proteinuria and reduced estimated glomerular filtration rate are independent risk... | 595 | fms |
easily applicable risk score model for contrast-induced nephropathy prediction after percutaneous coronary intervention a novel approach tailored to current practice <PERSOON> D, et al Validation of a new risk score to predict contrast-induced nephropathy after <PERSOON> A, et al Increased aortic stiffness predicts... | 597 | fms |
# maanden wanneer de patiënt een chronische ziekte heeft met een stabiele nierfunctie; Bepaal de eGFR binnen # tot # dagen na intravasculaire jodiumhoudende contrastmiddel toediening bij elke Indien er PC-AKI wordt gediagnostiseerd (volgens Kidney Disease Improving Global Outcomes criteria), vervolg de patiënt gedur... | 583 | fms |
Due to extensive standardization efforts both at the international and the national level, the inter- laboratory variability is far below ##% As a result of ongoing improvements in creatinine assays, methods are now available for selective measurement of creatinine with high reproducibility and small variation As a m... | 653 | fms |
difference (%) = #,## * â(#)* â(â(CVa) + â(CVw))) when the two consecutive measurements of creatinine differ by at least ##,#%, e g when a value of ### µmol/L increases to at least ### µmol/L or a value of ### µmol/L increases to at least ### µmol/<PERSOON> the recent validation of the CKD-EPI formula in a... | 657 | fms |
g creatinine, Cystatin C, beta trace), although only creatinine has thus far found widespread use in most clinical chemistry laboratories Serum creatinine measurements are the basis for creatinine-derived eGFR estimates Historically, routine measurement of creatinine was performed using colorimetric Jaffe methods <... | 570 | fms |
hypotension, hypertension or shock may correlate with the possible development of AKI but are not specific for <PERSOON> applicability of current risk models in clinical practice is With the use of an endogenous filtration marker it should be noted that any endogenous marker is influenced by several non-GFR determinant... | 570 | fms |
chronic or non-communicable diseases are of long (more than # months) duration and generally slow progression <PERSOON> main types are cardiovascular diseases, diabetes, chronic kidney diseases, chronic respiratory system diseases, chronic gastro-intestinal diseases, and chronic connective tissue and auto-immune In pa... | 607 | fms |
after CM administration to diagnose PC-AKI In case PC-AKI is diagnosed within <DATUM> days, additional follow-up is mandatory It is the expert opinion of the Working Group that further follow-up is mandatory for patients in whom PC-AKI is diagnosed, for at least ## days post-diagnosis In case of a major life-threaten... | 574 | fms |
identifying patients with eGFR (## ml/min/# ##m# and can reduce the need for eGFR assessments via laboratory or point-of-care techniques, especially in patients younger than ## No literature search was performed for this chapter <PERSOON> working group did not expect to find evidence for this question, since the clini... | 627 | fms |
<PERSOON> A, et al <PERSOON> revised Lund-Malmö GFR estimating equation outperforms MDRD and <PERSOON> L, et al <PERSOON> estimated glomerular filtration rate equation for the full age spectrum <PERSOON> P, et al Two novel equations to estimate kidney function in persons aged ## years or <PERSOON> MF, et al New e... | 694 | fms |
has been publshed focusing on patients with eGFR (## ml/min/# ##m# only, and subanalyses for this group within other RCTs were not performed Furthermore, independent of eGFR, all patients receiving CM should have a normal hydration status Dehydration should be corrected at all times before administering <PERSOON> mos... | 692 | fms |
NaCl # #% before, during and after CM administration will produce an infusion rate-dependent increase in tubular fluid volume, reduction in CM intratubular concentration, and slight increases in tubular pH <PERSOON> lower tubular concentrations of CM lead to reduced formation of reactive oxygen species Infusion of NaH... | 644 | fms |
#% (# of <PERSOON> positive results of this relatively short NaHCO # hydration schedule triggered a boom in RCTs comparing NaHCO # vs <PERSOON> mixture used in the landmark paper is not commercially available <PERSOON> most resembling commercially available concentrations are NaHCO <DATUM> #% (i e ### mEq/<PERSOON> ... | 599 | fms |
weighed against its potential benefit, especially in patients on chronic dialysis and with poor cardiac function and critical illness related fluid overload Note In critically ill patients lactated Ringerâs, a balanced crystalloid, may be preferable to saline hydration because of it somewhat lower osmolality and th... | 643 | fms |
NaHCO # in the prevention of PC-AKI prior to computed tomography pulmonary angiography with intravenous iodine-containing CM administration for suspected There is a moderate level of evidence that no hydration is non-inferior in preventing PC-AKI compared with intravenous pre- and post- hydration in patients with an eG... | 780 | fms |
<PERSOON>, ### described ### patients with eGFR (## ml/min/# ##m# undergoing chest CT for suspected pulmonary embolism Sixty-seven patients received no hydration and the remaining ## patients received ###ml <PERSOON>, ### included ### high risk patients (â¥##y), as indicated by the local (Dutch) and European guidelin... | 804 | fms |
a conventional level of alpha (# ##), only ### patients were included (<PERSOON>, ###) A total of nine RCTs on this subject have been published, but only two were considered suitable to be included in this literature summary Four RCTs included patients with normal kidney function (Trivedi, ###; Kong, ###; Akyuz, ###;... | 751 | fms |
with impaired kidney function undergoing <PERSOON> ###) with #,### patients were identified, that compared bicarbonate and saline hydration in a similar hydration scheme for coronary angiography All the studies were performed in patients with # Short schedule NaHCO # vs long schedule NaCl (#ml/kg/h for ##h pre- and ... | 747 | fms |
No significant difference was found between patients that underwent bicarbonate versus saline hydration Risk Ratio (RR) # ## (##% CI # ## â # ##), # All other hydration schedules comparing bicarbonate plus saline to saline or to bicarbonate only A total cases, were considered suitable for this literature summary... | 732 | fms |
versus sodium bicarbonate hydration comparisons <PERSOON> number of adverse events was often not reported, and when reported was low In the <PERSOON> ### study, mentioned in the paragraph above, Acute heart failure due to volume expansion (based on the treating physicianâs clinical judgement) occurred in none of th... | 709 | fms |
urine bag After an initial bolus of ###ml NaCl # #% infused over ## minutes, patients receive furosemide, # ##mg/kg, to achieve a urinary flow of at least ###ml/h Once this is achieved, the procedure is performed <PERSOON> system keeps urinary flow )###ml/h for the next # hours, balancing between more papers describ... | 761 | fms |
control group of Marenzi, ### recieved a continuous intravenous infusion of isotonic saline at a rate of # ml/kg/h (# # ml/kg/h in case of left ventricular ejection fraction (##%) for at least ## h before and ## h after the procedure <PERSOON> control group of Usmiani, ### recieved ### mL isotonic saline i v administr... | 594 | fms |
consisted of ### patients with the same characteristics, undergoing the same procedure <PERSOON> groups received a bolus infusion, NaCl # #%, #ml/kg/h, # hour pre <PERSOON> control group received the same fluid at the same rate for # hours post <PERSOON> rate of post contrast fluid in the research Another approach, de... | 819 | fms |
of #% in the forced diuresis group versus ##% in the control group (p=# ##) One-year mortality was not significantly different in the intervention (#/##) and control (#/##) group, p=# ## Need for dialysis arose in #/## patients in the intervention group versus #/## in the control group, (pvalue not reported) Barbant... | 702 | fms |
or controlled hydration versus Patients recieving short schedules of hydration with either bicarbonate or saline for CAG/PCI Patients recieving short schedules for bicarbonate versus long schedule for saline for CAG/PCI Patients recieving bicarbonate or saline hydration in âotherâ hydration schemes for coronary ang... | 679 | fms |
risk, and a number needed to treat of ### <PERSOON> databases Medline (OVID), Embase and the Cochrane Library were searched from January ### to ##th of <PERSOON> ### using relevant search terms for systematic reviews (SRs), randomized controlled trials (RCTs) and observational studies (OBS) Search terms are shown in ... | 649 | fms |
Kemaloglu Oz T, et al Efficacy of oral hydration in the prevention of contrast-induced acute kidney <PERSOON> P, et al Acute kidney injury with the renalguard system in patients undergoing <PERSOON> O, et al Prevention of contrast-induced nephropathy in diabetic patients with impaired renal function a randomized, d... | 587 | fms |
###;##(#) ###-# <PERSOON> E, Poh KK, Lu Q, Et al Comparison of combination therapy of high-dose oral N-acetylcysteine and intravenous <PERSOON> A, et al A randomized trial of saline hydration to prevent contrast nephropathy in chronic <PERSOON> VO, Lasevitch R, <PERSOON> VC, et al Hydration with sodium bicarbonate ... | 594 | fms |
coronary angiography or intervention <PERSOON> M, et al Effects of hydration in contrast-induced acute kidney injury after primary angioplasty a <PERSOON> E, et al Acute kidney injury after primary angioplasty effect of different hydration <PERSOON> I, et al Prevention of contrast nephropathy by furosemide with m... | 566 | fms |
et al Prevention of contrast-induced nephropathy by central venous pressureâguided fluid administration in chronic kidney disease and congestive heart failure patients JACC Cardiovasc Intervent ###;#(#) ##-## Ratcliffe JA, Thiagarajah P, <PERSOON> J, et al Prevention of contrast-induced nephropathy A randomized... | 564 | fms |
<PERSOON> C, et al AKIGUARD (Acute Kidney Injury GUARding Device) trial in-hospital and one-year <PERSOON> M, et al RenalGuard System for the prevention of acute kidney injury in patients <PERSOON> W, <PERSOON> M, et al Oral versus intravenous hydration and renal function in diabetic patients Use of Statins and hyd... | 581 | fms |
valves (TAVR) or In conclusion, atorvastatin and rosuvastatin, when administered at high doses and before iodine-containing contrast administration in statin-naïve patients with reduced renal function undergoing coronary angiography or percutaneous coronary intervention (PCI), have a beneficial effect on the preventio... | 626 | fms |
<PERSOON>, ### evaluated the protective effects of statins on PC-AKI, renal replacement therapy and mortality in patients undergoing coronary angiography/percutaneous intervention Here we encompassed only the # RCTs (n=###) that were included in the subgroup analysis that focused on patients with renal dysfunction <P... | 725 | fms |
oral atorvastatin (## mg daily for ## h) before PCI Qiao, ### treated the intervention group with rosuvastatin (## mg everyday for at least ## hours before and ## hours after CM administration for PCI) Shehata, ### provided both the intervention and control group in addition to periprocedural intravenous infusion of ... | 665 | fms |
# ##; Figure # <PERSOON>-analysis of studies that evaluated the ef f ects of high dose rosuvastatin or In the study of <PERSOON> (###) one patient in the placebo group needed haemodialysis for renal failure # days after coronary angiography Toso (###) reported one case of temporally hemofiltration in the placebo group... | 619 | fms |
the outcomes start dialysis and mortality, the level of evidence was decreased from high to very low, # point <PERSOON> statins when compared to no statins reduce the incidence of PC-AKI in patients with pre-existent reduced P (patient category) patients undergoing radiological examinations with reduced kidney function... | 645 | fms |
randomized controlled studies <PERSOON> most important study characteristics and results are included in the evidence tables <PERSOON> C, et al Impact of Rosuvastatin on contrast-induced acute kidney injury in patients at high <PERSOON> G, <PERSOON> L, et al Short-term rosuvastatin therapy for prevention of contras... | 615 | fms |
controlled trial <PERSOON> M, et al Pharmacologic prophylaxis for contrast-induced acute kidney injury Intervent Cardiol Use of prophylactic N-acetylcysteine (NAC) in addition to hydration to reduce Dient profylaxe met N-acetylcysteine (NAC) te worden aanbevolen naast hydratie om de kans om PC-AKI te verkleinen bij ... | 565 | fms |
found that compared oral to intravenous N-acetylcysteine route of administration in patients undergoing intravascular contrast Intervention with NAC is without risk, cheap, and generally available, and there are theoretical arguments that NAC may provide reduction of CI-AKI Despite the theoretically potential kidney p... | 553 | fms |
injury was similar between patients receiving IV contrast and patients receiving an In addition, it is also difficult to distinguish the effects of contrast media from the effects of physiologic confounders that could either elevate or reduce serum creatinine in patients undergoing radiologic studies There is also a po... | 717 | fms |
Poletti, ###; Poletti, ###; Tepel, ###) with ### patients was included Three studies described emergency patients (Kama, ###; Poletti, ###; Poletti, ###) while two administered orally (Kitzler, ###; Tepel, ###), with the total doses varying between <DATUM> and <DATUM> In three doses varying between <DATUM> g (###mg... | 798 | fms |
###; <PERSOON>, ###) with ### patients with ### events showed that risk ratio of PC-AKI was not ###; Koc, ###; Kotlyar, ###; Sadineni, ###; Seyon, ###) with ### patients with ### events showed that <PERSOON> quality of evidence for the outcome PC-AKI was downgraded by two for imprecision (low number of events Figure # ... | 683 | fms |
## studies were excluded and ## studies definitely included in the literature summary Reasons for exclusion are described in the exclusion table During the search update, no more papers were included that described patients with a normal kidney function (eGFRâ¥## ml/min# ##m# ) <PERSOON> reason for this was that th... | 615 | fms |
<PERSOON> value of N-acetylcysteine in the prevention of radiocontrast agent-induced <PERSOON> MK, <PERSOON> SH, et al N-acetylcysteine for the prevention of contrast-induced nephropathy in the emergency Izani <PERSOON> in prevention of contrast induced nephropathy following <PERSOON> CJ, et al A randomized trial of ... | 602 | fms |
<PERSOON> ZZ, Schmerbach K, Lu Y, et al Iodinated contrast media cause direct tubular cell damage, leading to oxidative stress, low nitric oxide, and impairment of tubuloglomerular feedbackAm <PERSOON> JS, McDonald RJ, Carter RE, et al Risk of intravenous contrast materialâmediated acute kidney injury a <PERSOON> ... | 572 | fms |
<PERSOON> C, et al Prevention of radiographic-contrast-agentâinduced reductions in renal <PERSOON> C, et al Impact of high-dose N-acetylcysteine versus placebo on contrast-induced nephropathy and myocardial reperfusion injury in unselected patients with ST-segment elevation myocardial infarction Randomized Leipzig ... | 576 | fms |
studies showed significant differences in clinical meaningful endpoints such as need of renal replacement therapy Since the risk of renal replacement therapy after intravascular contrast media administration is low, none of the studies was powered Intervention with vitamin C is without risk, cheap, and generally avail... | 590 | fms |
low quality that administration of vitamin C (oral or intravenous) in addition to hydration is more effective than no administration of vitamin C for the prevention No studies were found evaluating the effects of vitamin C administration on PC-AKI in All studies were performed in patients undergoing CAG with or without... | 699 | fms |
and route of vitamin C, type of hydration and not included in the f inal meta-analysis because the study has appeared only in abstract f orm not included in the f inal meta-analysis because the study did not report restricting inclusion to Dvoršak, ### and Komiyama, ### reported that of the patients in the ascorbic ac... | 743 | fms |
other meta-analyses are presented as well in the Appendix One that includes the studies that appeared in abstract form as well (figure #) and one that includes all RCTs on vitamin C (figure #) <PERSOON> demonstrate a similar <PERSOON> level of quality of evidence was decreased from level high to level moderate, due t... | 642 | fms |
types hydration with intravenous (i v ) NaCl or bicarbonate, oral hydration; the control arm consisted of patients that received hydration only; at least one of the outcome measures was described PC-AKI, start dialysis, chronic decrease in kidney function, adverse effects of hydration (fluid overload, intensive care ... | 585 | fms |
###;##(#) ### <PERSOON> L, et al Ascorbate the most effective antioxidant in human blood plasma Adv Exp Med Biol <PERSOON> A, et al Prevention of contrast induced nephropathy in patients undergoing coronarography <PERSOON> Y, et al Is ascorbic acid effective in preventing contrast-induced acute kidney injury? <P... | 603 | fms |
contrastmiddel Staak ACE-remmers, angiotensine II receptorantagonisten of diuretica niet routinematig vooraf aan De werkgroep beveelt een nefrologisch consult aan, vooraf aan jodiumhoudend CM toediening, bij patiënten met een eGFR (## ml/kg/#,##m# , zodat er op individuele basis kan worden besloten om ACE-remmers, has... | 588 | fms |
and angiotensin receptor blockers can reduce glomerular filtration, a fully reversible process Thus, patients with very low glomerular reserve capacity which are dependent of postglomerular vasoconstriction may benefit from a temporary discontinuation of ACE-inhibitors and angiotensin receptor blockers regarding maint... | 597 | fms |
of diuretics may hamper glomerular filtration if their use causes hypovolemia and glomerular reserves are diminished In these cases, the additional use of iodine-containing CM may reduce glomerular filtration Finally, withholding diuretics might increase the risk of acute heart failure in chronic users of these agent... | 604 | fms |
contrast Several international guidelines therefore advise to withhold these drugs in patients undergoing elective procedures requiring intravascular contrast administration Implementation is however difficult, discontinuation is not without risk and whether withholding these agents in the day(s) prior to or followin... | 672 | fms |
NSAIDs or diuretics before the administration of intravascular contrast in euvolemic patients reduces the risk of post contrast acute kidney This literature summary describes # randomized controlled trials (RCTs) (Bainey, ###; Rosenstock, ###) Rosenstock, ### compared discontinuation of angiotensin converting enzyme (... | 741 | fms |
saline at # mL/kg/hour for at least an hour before contrast injection, intravenous normal saline at # mL/kg/hour during contrast exposure and # hours after the procedure or until discharge Serum creatinine levels No literature was found describing discontinuation of NSAIDs or diuretics prior to CM-enhanced CT in patie... | 721 | fms |
Due to heterogeneity in types of medications and interventions for which contrast administration was used, it blockers ##-## hours prior to CE-CT reduce the risk of adverse renal outcomes? blockers ##-## hours following CE-CT reduce the risk of adverse renal outcomes? P (patient category) patients with mild to moderate... | 645 | fms |
PC-AKI, start dialysis, decrease in residual kidney Based on title and abstract a total of ## studies were selected, all from the initial search After examination of full text a total of ## studies were excluded and # studies definitely included in the literature summary Two studies were included in the final literatu... | 597 | fms |
woorden bij het inplannen van een onderzoek met jodiumhoudend CM hoeft er geen rekening gehouden worden met het <PERSOON> present systematic review and meta-analysis shows that prophylactic HD increases the risk of PC-AKI in patient with CKD stage # to # (eGFR (## ml/min/# ##m# ), (albeit not significantly) but also t... | 619 | fms |
It is the opinion of the working group that the scheduling of an iodine-containing contrast-enhanced imaging study does not need to be adapted to the dialysis schedule of the <PERSOON> vice versa the schedule of chronic dialysis does not need to be adapted PC-AKI may increase cardiovascular morbidity and mortality Ho... | 657 | fms |
CKD stage <DATUM> (eGFR (## There is a very low level of evidence that prophylactic haemodialysis does not reduce the risk of PC-AKI compared to standard medical treatment in patients with chronic kidney disease There is a very low level of evidence that prophylactic hemo(dia)filtration does not reduce the risk of PC-A... | 698 | fms |
renal replacement therapy only after PCI (CRRTpost, n=##) or CRRT before and after PCI (CRRTpre-post, n=##) in CRRT consisted of continuous venovenous hemofiltration (CVVH) for patients with serum creatinine (### µmol/L or continuous venovenous hemodiafiltration (CVVHDF) for patients with serum creatinine )### µmol/L... | 724 | fms |
RCTs comparing HD to standard medical treatment (SMT), two only reported creatinine change after contrast medium administration (<PERSOON>, ###; <PERSOON>, ###) and not PC-AKI risk, and thus these studies also were excluded from the analysis When the three RCTs ##% in the HD group and ##% in the SMT group There was n... | 721 | fms |
of ## months (median) a worsening of kidney function was observed In addition, three of the studies investigating pre- and post-contrast hemofiltration found a reduction in mortality Marenzi (###) and Marenzi (###) reported a reduction in hospital mortality, while <PERSOON> quality of evidence for the outcome PC-AKI i... | 670 | fms |
treatment arm consisted out of patients receiving renal replacement therapy (haemodialysis, at least one of the outcome measures was described Contrast-induced nephropathy (CIN) / contrastinduced acute kidney injury (CI-AKI)/PC-AKI, start dialysis, chronic decrease in kidney function, adverse Based on title and abstra... | 623 | fms |
primary angioplasty <PERSOON> I, <PERSOON> G, et al <PERSOON> prevention of radiocontrast-agent-induced nephropathy by hemofiltration <PERSOON>, J et al, A randomized controlled trial comparing hydration therapy to additional <PERSOON> M, et al Effects of two different treatments with continuous renal replacement ... | 611 | fms |
is an anion-gap metabolic acidosis defined by serum lactate levels greater than # mmol/l and pH less than # ## and is a feared complication of the use of metformin Severe lactic acidosis causes multisystem fibrillation) dysfunction, and carries a )##% mortality risk There is no evidence that in patients with a normal... | 658 | fms |
by the kidney and eliminated unchanged in the urine This drug may therefore accumulate in patients with impaired kidney function as can occur in response to administration of iodine-containing CM Below which level of kidney function metformin should no longer be described is open to discussion Until very recently, t... | 630 | fms |
CM if renal function has not deteriorated No advice is given for patients on metformin receiving i a contrast who have an eGFR ## to ## ml/min/# ## m# In agreement with the FDA guideline metformin is contraindicated Goergen, ### has performed a systematic review of five guidelines and their underlying evidence conc... | 570 | fms |
can be given It is the opinion of the workgroup that in patients with an eGFR ⥠## ml/min/# ##m# the disadvantage of discontinuation of metformin with respect to the development of hyperglycaemia and administrative procedures does not weigh against its continuation as the chance of developing PC-AKI in these patient... | 582 | fms |
intravenously or intraarterially? It is not clear whether cessation of metformin in patients undergoing intravascular contrast administration for radiological examination is effective for decreasing the risk of metforminassociated lactic acidosis and hyperglycaemia One systematic review (Georgen, ###) was identified t... | 607 | fms |
Embase and the Cochrane Library were searched from January ### up to April ### using relevant search terms for systematic reviews (SRs), randomized controlled trials (RCTs) and adult patients who underwent radiological examination using contrast media (including radiological at least one of the outcome measures was des... | 591 | fms |
Prabhakar H, et al Metformin-associated lactic acidosis following contrast media-induced nephrotoxicity Lalau JD, Arnouts P, <PERSOON> A, et al Metformin and other antidiabetic agents in renal failure patients <PERSOON> ES, et al Lactate levels in Asian patients with type # diabetes mellitus on metformin and its a... | 572 | fms |
PC-AKI definition, a lower threshold of eGFR for hydration indication, another type of hydration (bicarbonate) as a recommended preventive measure and a conservative attitude towards preventive measures for PC-AKI other than hydration To enhance the implementation of this guideline, changes in the organizational struc... | 590 | fms |
Startpagina - Richtlijn diagnostiek en beleid bij volwassenen met chronische nierschade (CNS) Medicamenteuze behandeling van Cardiovasculaire en renale risicofactoren bij chronische nierschade (CNS) Medicamenteuze behandeling van secundaire metabole gevolgen van chronische nierschade (CNS) Startpagina - Richtlijn diagn... | 590 | fms |
Ziekenhuisapothekers en de Nederlandse Vereniging voor Klinische Chemie en Laboratoriumgeneeskunde Het patiëntenperspectief werd gewaarborgd door participatie door de Nierpatiënten Vereniging <LOCATIE> De werkgroep werd methodologisch en procedureel ondersteund Aanvullend aan de multidisciplinaire modules is een aa... | 635 | fms |
grenzen voor nierfunctie en albuminurie worden aanbevolen om chronische nierschade te definiëren? Voor classificatie van albuminurie wordt een indeling in normaal (A#), matig verhoogd (A#) en ernstig verhoogd Voor nierfunctiebepaling wordt schatting middels de CKD-EPI formule aanbevolen, waarbij creatinine selectief E... | 615 | fms |
andere terminologie inspanningen op het gebied van implementatie vereisen De termen normaal, matig verhoogd en ernstig verhoogd sluiten echter meer aan bij de internationale literatuur De Het bepalen van de nierfunctie kent een bepaalde mate van onzekerheid, afhankelijk van bijvoorbeeld spiermassa in het geval van cr... | 582 | fms |
kader van cardiovasculair risicomanagement of diabetes mellitus, zodat een vergelijking met de eerdere nierfunctie mogelijk is Bij een deel van de patiënten is er geen eerdere nierfunctie voorhanden De richtlijnwerkgroep vindt een tussenpoze van # maanden te lang voor het bevestigen van een nieuwe afwijkende nierfun... | 615 | fms |
oftewel âkritischâ verschil met ##% zekerheid gedetecteerd als de twee opeenvolgende creatinine metingen minimaal ##% verschillen, bijvoorbeeld als een uitslag van ### µmol/l tot minstens ### µmol/l toeneemt of een uitslag van ### µmol/l tot minstens ### µmol/l Bij een eGFR tot maximaal ## ml/min/#,## m# kan o... | 701 | fms |
een zodanig overlijden en een #,## (#,#<DATUM> ##)-voudig verhoogd risico op noodzaak voor dialyse of transplantatie [Turin, ###a,b] In een daaropvolgende studie van het Chronic Kidney Disease Prognosis Consortium (CKD-PC) werd aangetoond dat een ##% achteruitgang in eGFR over een periode van <LEEFTIJD> jaar gepaard g... | 653 | fms |
Biopsie studies bij gezonde nierdonoren hebben aangetoond dat bij een belangrijk deel van deze patiënten nefrosclerose wordt gevonden, waarvan de ernst geassocieerd is met de mate van nierfunctieverlies [Rule, ###] CNS draagt bij aan een verhoging van het cardiovasculaire risico, waarbij is aangetoond dat het relatie... | 556 | fms |
<PERSOON> Y, et al , Chronic Kidney Disease Prognosis Consortium <PERSOON> and association of kidney Hemmelgarn BR, <PERSOON> BJ et al Overview of the <PERSOON> K et al Slower decline of glomerular filtration rate in the Japanese general population a study equation for estimating glomerular filtration rate <PERSOO... | 568 | fms |
stadiumindeling wordt aanbevolen voor het indelen van chronische nierschade? Voor het stadiëren van chronische nierschade en het bepalen van het risico op cardiovasculaire schade, progressie van nierschade en mortaliteit wordt aanbevolen de onderstaande tabel (tabel #) te gebruiken De kleurcodering in deze tabel is g... | 588 | fms |
gaan uit van een indeling op basis van cardiovasculair risico welke is gebaseerd op nierfunctie (ingedeeld in # stadia) en nog een uitzonderingspositie aan voor jongvolwassenen, in tegenstelling tot de KDIGO richtlijn Welke factoren worden betrokken in de evaluatie van de oorzaak van chronische nierschade en welke gro... | 589 | fms |
CNS is over het algemeen gebaseerd op een verlaagde eGFR en/of een verhoogde albuminurie Deze # parameters zeggen niets over de oorzaak van de chronische nierschade Omdat de prognose van chronische nierschade mede afhankelijk is van de oorzaak, is vaak nadere diagnostiek gewenst Dat onderzoek begint met een anamnese... | 592 | fms |
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