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wikidoc
FOSL1
FOSL1 Fos-related antigen 1 (FRA1) is a protein that in humans is encoded by the FOSL1 gene. # Function The Fos gene family consists of 4 members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor comple...
FOSL1 Fos-related antigen 1 (FRA1) is a protein that in humans is encoded by the FOSL1 gene.[1][2] # Function The Fos gene family consists of 4 members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor...
https://www.wikidoc.org/index.php/FOSL1
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wikidoc
FOXA1
FOXA1 Forkhead box protein A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha (HNF-3A), is a protein that in humans is encoded by the FOXA1 gene. # Function FOXA1 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific trans...
FOXA1 Forkhead box protein A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha (HNF-3A), is a protein that in humans is encoded by the FOXA1 gene.[1][2][3] # Function FOXA1 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-spec...
https://www.wikidoc.org/index.php/FOXA1
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wikidoc
FOXC2
FOXC2 Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1 (MFH1) is a protein that in humans is encoded by the FOXC2 gene. FOXC2 is a member of the fork head box (FOX) family of transcription factors. # Structure and fun...
FOXC2 Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1 (MFH1) is a protein that in humans is encoded by the FOXC2 gene.[1][2] FOXC2 is a member of the fork head box (FOX) family of transcription factors. # Structure ...
https://www.wikidoc.org/index.php/FOXC2
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wikidoc
FOXD3
FOXD3 Forkhead box D3 also known as FOXD3 is a forkhead protein that in humans is encoded by the FOXD3 gene. # Function This gene belongs to the forkhead protein family of transcription factors which is characterized by a DNA-binding forkhead domain. FoxD3 functions as a transcriptional repressor and contains the C-t...
FOXD3 Forkhead box D3 also known as FOXD3 is a forkhead protein that in humans is encoded by the FOXD3 gene.[1] # Function This gene belongs to the forkhead protein family of transcription factors which is characterized by a DNA-binding forkhead domain. FoxD3 functions as a transcriptional repressor and contains the...
https://www.wikidoc.org/index.php/FOXD3
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wikidoc
FOXE1
FOXE1 Forkhead box protein E1 is a protein that in humans is encoded by the FOXE1 gene. # Location The FOXE1 gene is located on the long (q) arm of chromosome 9 at position 22 # Function This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain....
FOXE1 Forkhead box protein E1 is a protein that in humans is encoded by the FOXE1 gene.[1][2][3] # Location The FOXE1 gene is located on the long (q) arm of chromosome 9 at position 22[4] # Function This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct for...
https://www.wikidoc.org/index.php/FOXE1
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wikidoc
FOXE3
FOXE3 Forkhead box protein E3 (FOXE3) also known as forkhead-related transcription factor 8 (FREAC-8) is a protein that in humans is encoded by the FOXE3 gene located on the short arm of chromosome 1. # Function FOXE3 is a forkhead-box transcription factor which is involved in the proper formation of the ocular lens a...
FOXE3 Forkhead box protein E3 (FOXE3) also known as forkhead-related transcription factor 8 (FREAC-8) is a protein that in humans is encoded by the FOXE3 gene located on the short arm of chromosome 1.[1] # Function FOXE3 is a forkhead-box transcription factor which is involved in the proper formation of the ocular le...
https://www.wikidoc.org/index.php/FOXE3
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FOXG1
FOXG1 Forkhead box protein G1 is a protein that in humans is encoded by the FOXG1 gene. # Function This gene belongs to the forkhead family of transcription factors that is characterized by a distinct forkhead domain. The complete function of this gene has not yet been determined; however, it has been shown to play a ...
FOXG1 Forkhead box protein G1 is a protein that in humans is encoded by the FOXG1 gene.[1][2][3] # Function This gene belongs to the forkhead family of transcription factors that is characterized by a distinct forkhead domain. The complete function of this gene has not yet been determined; however, it has been shown ...
https://www.wikidoc.org/index.php/FOXG1
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wikidoc
FOXH1
FOXH1 Forkhead box protein H1 is a protein that in humans is encoded by the FOXH1 gene. # Function FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 protein binds SMAD2 and activates an activin response element via binding the DNA motif TGT(G/T)(T/G)ATT. # Interactions FOXH1 has bee...
FOXH1 Forkhead box protein H1 is a protein that in humans is encoded by the FOXH1 gene.[1][2] # Function FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 protein binds SMAD2 and activates an activin response element via binding the DNA motif TGT(G/T)(T/G)ATT.[2] # Interactions FOX...
https://www.wikidoc.org/index.php/FOXH1
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wikidoc
FOXJ1
FOXJ1 Forkhead box protein J1 is a protein that in humans is encoded by the FOXJ1 gene. It is a member of the Forkhead/winged helix (FOX) family of transcription factors that is involved in ciliogenesis. FOXJ1 is expressed in ciliated cells of the lung, choroid plexus, reproductive track, embryonic kidney and pre-somit...
FOXJ1 Forkhead box protein J1 is a protein that in humans is encoded by the FOXJ1 gene.[1] It is a member of the Forkhead/winged helix (FOX) family of transcription factors that is involved in ciliogenesis.[2] FOXJ1 is expressed in ciliated cells of the lung,[3] choroid plexus,[4] reproductive track,[5] embryonic kidn...
https://www.wikidoc.org/index.php/FOXJ1
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wikidoc
FOXM1
FOXM1 Forkhead box protein M1 is a protein that in humans is encoded by the FOXM1 gene. The protein encoded by this gene is a member of the FOX family of transcription factors. Its potential as a target for future cancer treatments led to it being designated the 2010 Molecule of the Year. # Function FOXM1 is known to ...
FOXM1 Forkhead box protein M1 is a protein that in humans is encoded by the FOXM1 gene.[1][2] The protein encoded by this gene is a member of the FOX family of transcription factors.[1][3] Its potential as a target for future cancer treatments led to it being designated the 2010 Molecule of the Year.[4] # Function FO...
https://www.wikidoc.org/index.php/FOXM1
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wikidoc
FOXO1
FOXO1 Forkhead box protein O1 (FOXO1) also known as forkhead in rhabdomyosarcoma is a protein that in humans is encoded by the FOXO1 gene. FOXO1 is a transcription factor that plays important roles in regulation of gluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a preadi...
FOXO1 Forkhead box protein O1 (FOXO1) also known as forkhead in rhabdomyosarcoma is a protein that in humans is encoded by the FOXO1 gene.[1] FOXO1 is a transcription factor that plays important roles in regulation of gluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a pr...
https://www.wikidoc.org/index.php/FOXO1
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wikidoc
FOXO3
FOXO3 Forkhead box O3, also known as FOXO3 or FOXO3a, is a human protein encoded by the FOXO3 gene. # Function FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. There are three other FoxO family members in humans, FOXO1, ...
FOXO3 Forkhead box O3, also known as FOXO3 or FOXO3a, is a human protein encoded by the FOXO3 gene.[1] # Function FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. There are three other FoxO family members in humans, FOX...
https://www.wikidoc.org/index.php/FOXO3
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wikidoc
FOXO4
FOXO4 Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene. It is located on the long arm of the X chromosome from base pair 71,096,148 to 71,103,533. # Structure and function FOXO4 is a member of the forkhead family transcription factors O subclass, which is characterized by a winged helix...
FOXO4 Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene.[1][2] It is located on the long arm of the X chromosome from base pair 71,096,148 to 71,103,533.[3] # Structure and function FOXO4 is a member of the forkhead family transcription factors O subclass, which is characterized by a wi...
https://www.wikidoc.org/index.php/FOXO4
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wikidoc
FOXP1
FOXP1 Forkhead box protein P1 is a protein that in humans is encoded by the FOXP1 gene. FOXP1 is necessary for the proper development of the brain, heart, and lung in mammals. It is a member of the large FOX family of transcription factors. # Function This gene belongs to subfamily P of the forkhead box (FOX) transcr...
FOXP1 Forkhead box protein P1 is a protein that in humans is encoded by the FOXP1 gene. FOXP1 is necessary for the proper development of the brain, heart, and lung in mammals. It is a member of the large FOX family of transcription factors. # Function This gene belongs to subfamily P of the forkhead box (FOX) transc...
https://www.wikidoc.org/index.php/FOXP1
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wikidoc
FOXP2
FOXP2 Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the FOXP2 gene, also known as CAGH44, SPCH1 or TNRC10, and is required for proper development of speech and language. The gene is shared with many vertebrates, where it generally plays a role in communication (for instance, the developmen...
FOXP2 Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the FOXP2 gene, also known as CAGH44, SPCH1 or TNRC10, and is required for proper development of speech and language.[1] The gene is shared with many vertebrates, where it generally plays a role in communication (for instance, the develo...
https://www.wikidoc.org/index.php/FOXP2
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wikidoc
FOXP3
FOXP3 FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Regulatory T cells generally turn the immune respon...
FOXP3 FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses.[1] A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells.[2][3][4] Regulatory T cells generally turn the ...
https://www.wikidoc.org/index.php/FOXP3
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wikidoc
FSTL1
FSTL1 Follistatin-related protein 1 is a protein that in humans is encoded by the FSTL1 gene. # Structure This gene encodes a protein with similarity to follistatin, an BMP-4-binding protein. It binds to BMP-4 and TGF-β1, but not Activin A. It contains an FS module (a follistatin-like sequence containing 10 conserved ...
FSTL1 Follistatin-related protein 1 is a protein that in humans is encoded by the FSTL1 gene.[1][2][3] # Structure This gene encodes a protein with similarity to follistatin, an BMP-4-binding protein.[4] It binds to BMP-4 and TGF-β1, but not Activin A.[4] It contains an FS module (a follistatin-like sequence containi...
https://www.wikidoc.org/index.php/FSTL1
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wikidoc
FXYD3
FXYD3 FXYD domain-containing ion transport regulator 3 is a protein that in humans is encoded by the FXYD3 gene. # Function This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly c...
FXYD3 FXYD domain-containing ion transport regulator 3 is a protein that in humans is encoded by the FXYD3 gene.[1][2][3] # Function This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and ...
https://www.wikidoc.org/index.php/FXYD3
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wikidoc
FXYD5
FXYD5 FXYD domain-containing ion transport regulator 5 also named dysadherin (human) or RIC (mouse) is a protein that in humans is encoded by the FXYD5 gene. # Function This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PF...
FXYD5 FXYD domain-containing ion transport regulator 5 also named dysadherin (human) or RIC (mouse) is a protein that in humans is encoded by the FXYD5 gene.[1] # Function This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequenc...
https://www.wikidoc.org/index.php/FXYD5
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wikidoc
FXYD6
FXYD6 FXYD6 (pronounced fix-id six), or FXYD domain-containing ion transport regulator 6, is a gene which is located at the 11q23.3 (chromosome 11 locus 23.3). The FXYD6 protein contains 95 amino acids, and can be found in all human tissues except blood. This gene belongs to the FXYD family of ion transport regulators...
FXYD6 FXYD6 (pronounced fix-id six), or FXYD domain-containing ion transport regulator 6, is a gene which is located at the 11q23.3 (chromosome 11 locus 23.3). The FXYD6 protein contains 95 amino acids, and can be found in all human tissues except blood. This gene belongs to the FXYD family of ion transport regulator...
https://www.wikidoc.org/index.php/FXYD6
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wikidoc
Lipid
Lipid Lipids are broadly defined as any fat-soluble (lipophilic), naturally-occurring molecule, such as fats, oils, waxes, cholesterol, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage,...
Lipid Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Template:Editor help Lipids are broadly defined as any fat-soluble (lipophilic), naturally-occurring molecule, such as fats, oils, waxes, cholesterol, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, an...
https://www.wikidoc.org/index.php/Fats
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wikidoc
Favus
Favus Favus (Latin for "honeycomb") is a disease of the scalp, but occurring occasionally on any part of the skin, and even at times on mucous membranes. The uncomplicated appearance is that of a number of yellowish, circular, cup-shaped crusts (scutula) grouped in patches like a piece of honeycomb, each about the size...
Favus Favus (Latin for "honeycomb") is a disease of the scalp, but occurring occasionally on any part of the skin, and even at times on mucous membranes. The uncomplicated appearance is that of a number of yellowish, circular, cup-shaped crusts (scutula) grouped in patches like a piece of honeycomb, each about the siz...
https://www.wikidoc.org/index.php/Favus
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wikidoc
Meter
Meter # Overview The metre or meter (symbol: m) is the fundamental unit of length in the International System of Units (SI). The metre was originally defined by a prototype object meant to represent ​1⁄10,000,000 the distance between the poles and the Equator. Today, it is defined as ​1⁄299,792,458 of a light-second. ...
Meter Template:Unit of length # Overview The metre or meter[1] (symbol: m) is the fundamental unit of length in the International System of Units (SI). The metre was originally defined by a prototype object meant to represent ​1⁄10,000,000 the distance between the poles and the Equator. Today, it is defined as ​1⁄299...
https://www.wikidoc.org/index.php/Femtometre
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wikidoc
Femur
Femur In humans, it is the longest, most voluminous, and strongest bone. The average human femur is 48 centimeters (19 in) in length and 2.34 cm (0.92 in) in diameter and can support up to 30 times the weight of an adult. It forms part of the hip (at the acetabulum) and part of the knee. The word femur is Latin for thi...
Femur Template:Infobox Bone Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] In humans, it is the longest, most voluminous, and strongest bone. The average human femur is 48 centimeters (19 in) in length and 2.34 cm (0.92 in) in diameter and can support up to 30 times the weight of an adult.[1] It forms part of the ...
https://www.wikidoc.org/index.php/Femur
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wikidoc
Fetus
Fetus A fetus (or foetus, or fœtus) is a developing mammal or other viviparous vertebrate, after the embryonic stage and before birth. The plural is fetuses (foetuses, fœtuses) or, very rarely, foeti. In humans, the fetal stage of prenatal development begins about eight weeks after fertilization, when the major struc...
Fetus Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] A fetus (or foetus, or fœtus) is a developing mammal or other viviparous vertebrate, after the embryonic stage and before birth. The plural is fetuses (foetuses, fœtuses) or, very rarely, foeti. In humans, the fetal stage of prenatal development begins about e...
https://www.wikidoc.org/index.php/Fetal
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wikidoc
Fique
Fique Fique or Cabuya is a natural fiber that grows in the leaves of the fique plant (Furcraea sp.), a xerophytic monocot native to Andean regions of Colombia. From here it was extended to Venezuela and the east coast of Brazil. Common names: Fique, Cabuya, Pita, Penca, Maguey, Cabui, Chuchao or Coquiza. The fiqu...
Fique Fique or Cabuya is a natural fiber that grows in the leaves of the fique plant (Furcraea sp.), a xerophytic monocot native to Andean regions of Colombia. From here it was extended to Venezuela and the east coast of Brazil. Common names: Fique, Cabuya, Pita, Penca, Maguey, Cabui, Chuchao or Coquiza[1]. The ...
https://www.wikidoc.org/index.php/Fique
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wikidoc
Flame
Flame # Overview A flame is often defined as the visible (light-emitting) part of a fire. Physically, it is caused by a highly exothermic reaction (for example, combustion, a self-sustaining oxidation reaction) taking place in a thin zone. A flame generally emits light, by two different mechanisms which will be descri...
Flame # Overview A flame is often defined as the visible (light-emitting) part of a fire. Physically, it is caused by a highly exothermic reaction (for example, combustion, a self-sustaining oxidation reaction) taking place in a thin zone. A flame generally emits light, by two different mechanisms which will be descri...
https://www.wikidoc.org/index.php/Flame
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wikidoc
Flora
Flora # Overview In botany, flora (plural: floras or florae) has two meanings. The first meaning, or flora of an area or of time period, refers to all plant life occurring in an area or time period, especially the naturally occurring or indigenous plant life. The second meaning refers to a book or other work which des...
Flora Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview In botany, flora (plural: floras or florae) has two meanings. The first meaning, or flora of an area or of time period, refers to all plant life occurring in an area or time period, especially the naturally occurring or indigenous plant life. The sec...
https://www.wikidoc.org/index.php/Flora
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wikidoc
Fluid
Fluid # Overview A fluid is defined as a substance that continually deforms (flows) under an applied shear stress regardless of how small the applied stress. All liquids and all gases are fluids. Fluids are a subset of the phases of matter and include liquids, gases, plasmas and, to some extent, plastic solids. Liquid...
Fluid Template:Continuum mechanics # Overview A fluid is defined as a substance that continually deforms (flows) under an applied shear stress regardless of how small the applied stress. All liquids and all gases are fluids. Fluids are a subset of the phases of matter and include liquids, gases, plasmas and, to some ...
https://www.wikidoc.org/index.php/Fluid
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wikidoc
GLUT5
GLUT5 GLUT5 is a fructose transporter expressed on the apical border of enterocytes in the small intestine. GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal...
GLUT5 GLUT5 is a fructose transporter expressed on the apical border of enterocytes in the small intestine.[1] GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skel...
https://www.wikidoc.org/index.php/Fructose_carrier
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wikidoc
Furan
Furan # Overview Furan, also known as furane and furfuran, is a heterocyclic organic compound. It is typically derived by the thermal decomposition of pentose-containing materials, cellolosic solids especially pine-wood. Furan is a colorless, flammable, highly volatile liquid with a boiling point close to room temp...
Furan Template:Chembox new Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Furan, also known as furane and furfuran, is a heterocyclic organic compound. It is typically derived by the thermal decomposition of pentose-containing materials, cellolosic solids especially pine-wood. Furan is a colorless, ...
https://www.wikidoc.org/index.php/Furan
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wikidoc
Furin
Furin Furin is a protein that in humans is encoded by the FURIN gene. Some proteins are inactive when they are first synthesized, and must have sections removed in order to become active. Furin cleaves these sections and activates the proteins. It was named furin because it was in the upstream region of an oncogene kno...
Furin Furin is a protein that in humans is encoded by the FURIN gene. Some proteins are inactive when they are first synthesized, and must have sections removed in order to become active. Furin cleaves these sections and activates the proteins.[1][2][3][4] It was named furin because it was in the upstream region of an...
https://www.wikidoc.org/index.php/Furin
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wikidoc
G-LOC
G-LOC # Overview G-LOC, abbreviated from G-force induced Loss Of Consciousness, is a term generally used in aerospace physiology to describe a loss of consciousness arising from excessive and sustained g-forces draining blood away from the brain causing cerebral hypoxia. The condition is most likely to affect pilots ...
G-LOC # Overview G-LOC, abbreviated from G-force induced Loss Of Consciousness, is a term generally used in aerospace physiology to describe a loss of consciousness arising from excessive and sustained g-forces draining blood away from the brain causing cerebral hypoxia. The condition is most likely to affect pilots ...
https://www.wikidoc.org/index.php/G-LOC
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wikidoc
G6PC3
G6PC3 Glucose-6-phosphatase 3, also known as glucose-6-phosphatase beta, is an enzyme that in humans is encoded by the G6PC3 gene. # Function This gene encodes the catalytic subunit of glucose 6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose 6-phosphat...
G6PC3 Glucose-6-phosphatase 3, also known as glucose-6-phosphatase beta, is an enzyme that in humans is encoded by the G6PC3 gene.[1][2][3] # Function This gene encodes the catalytic subunit of glucose 6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose ...
https://www.wikidoc.org/index.php/G6PC3
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wikidoc
GABPA
GABPA GA-binding protein alpha chain is a protein that in humans is encoded by the GABPA gene. # Function This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor ...
GABPA GA-binding protein alpha chain is a protein that in humans is encoded by the GABPA gene.[1] # Function This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory fac...
https://www.wikidoc.org/index.php/GABPA
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wikidoc
GABRD
GABRD Gamma-aminobutyric acid receptor subunit delta is a protein that in humans is encoded by the GABRD gene. # Function γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABAA receptors, which are ligand-gated chloride channels. The GABAA receptor is general...
GABRD Gamma-aminobutyric acid receptor subunit delta is a protein that in humans is encoded by the GABRD gene.[1][2][3] # Function γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABAA receptors, which are ligand-gated chloride channels. The GABAA receptor ...
https://www.wikidoc.org/index.php/GABRD
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wikidoc
GABRE
GABRE Gamma-aminobutyric acid receptor subunit epsilon is a protein that in humans is encoded by the GABRE gene. The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the faste...
GABRE Gamma-aminobutyric acid receptor subunit epsilon is a protein that in humans is encoded by the GABRE gene.[1][2][3] The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates...
https://www.wikidoc.org/index.php/GABRE
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wikidoc
GATA1
GATA1 GATA-binding factor 1 or GATA-1 (also termed Erythroid transcription factor) is the founding member of the GATA family of transcription factors. This protein is widely expressed throughout vertebrate species. In humans and mice, it is encoded by the GATA1 and Gata1 genes, respectively. These genes are located on...
GATA1 GATA-binding factor 1 or GATA-1 (also termed Erythroid transcription factor) is the founding member of the GATA family of transcription factors. This protein is widely expressed throughout vertebrate species. In humans and mice, it is encoded by the GATA1 and Gata1 genes, respectively. These genes are located o...
https://www.wikidoc.org/index.php/GATA1
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wikidoc
GATA2
GATA2 GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes. It regulates a large number of genes that are critical for the embryonic development, self-renewal, maintenance, and functionality of blood-forming, lympathic system-forming, and other tissue-...
GATA2 GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes.[1] It regulates a large number of genes that are critical for the embryonic development, self-renewal, maintenance, and functionality of blood-forming, lympathic system-forming, and other tis...
https://www.wikidoc.org/index.php/GATA2
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wikidoc
GATA3
GATA3 GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes. The GATA3 transcription factor is critical for the embryonic development of various tissues as w...
GATA3 GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes.[1][2][3] The GATA3 transcription factor is critical for the embryonic development of various ti...
https://www.wikidoc.org/index.php/GATA3
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wikidoc
GATA4
GATA4 Transcription factor GATA-4 is a protein that in humans is encoded by the GATA4 gene. # Function This gene encodes a member of the GATA family of zinc finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate...
GATA4 Transcription factor GATA-4 is a protein that in humans is encoded by the GATA4 gene.[1] # Function This gene encodes a member of the GATA family of zinc finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regu...
https://www.wikidoc.org/index.php/GATA4
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wikidoc
GATA5
GATA5 Transcription factor GATA-5 is a protein that in humans is encoded by the GATA5 gene. # Function The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is esse...
GATA5 Transcription factor GATA-5 is a protein that in humans is encoded by the GATA5 gene.[1][2] # Function The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction ...
https://www.wikidoc.org/index.php/GATA5
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wikidoc
GATA6
GATA6 Transcription factor GATA-6, also known as GATA-binding factor 6 (GATA6), is protein that in humans is encoded by the GATA6 gene. The gene product preferentially binds (A/T/C)GAT(A/T)(A) of the consensus binding sequence. # Clinical significance Mutations in the gene have been linked with pancreatic agenesis and...
GATA6 Transcription factor GATA-6, also known as GATA-binding factor 6 (GATA6), is protein that in humans is encoded by the GATA6 gene.[1] The gene product preferentially binds (A/T/C)GAT(A/T)(A) of the consensus binding sequence.[2] # Clinical significance Mutations in the gene have been linked with pancreatic agene...
https://www.wikidoc.org/index.php/GATA6
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wikidoc
GDF10
GDF10 Growth differentiation factor 10 (GDF10) also known as bone morphogenetic protein 3B (BMP-3B) is a protein that in humans is encoded by the GDF10 gene. GDF10 belongs to the transforming growth factor beta superfamily that is closely related to bone morphogenetic protein-3 (BMP3). It plays a role in head formation...
GDF10 Growth differentiation factor 10 (GDF10) also known as bone morphogenetic protein 3B (BMP-3B) is a protein that in humans is encoded by the GDF10 gene.[1] GDF10 belongs to the transforming growth factor beta superfamily that is closely related to bone morphogenetic protein-3 (BMP3). It plays a role in head forma...
https://www.wikidoc.org/index.php/GDF10
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wikidoc
GDF11
GDF11 Growth differentiation factor 11 (GDF11) also known as bone morphogenetic protein 11 (BMP-11) is a protein that in humans is encoded by the growth differentiation factor 11 gene. It acts as a cytokine. The bone morphogenetic protein group is characterized by a polybasic proteolytic processing site, which is cleav...
GDF11 Growth differentiation factor 11 (GDF11) also known as bone morphogenetic protein 11 (BMP-11) is a protein that in humans is encoded by the growth differentiation factor 11 gene.[1] It acts as a cytokine[citation needed]. The bone morphogenetic protein group is characterized by a polybasic proteolytic processing...
https://www.wikidoc.org/index.php/GDF11
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wikidoc
GDF15
GDF15 Growth/differentiation factor 15 (GDF15) was first identified as Macrophage inhibitory cytokine-1 or MIC-1. It is a protein belonging to the transforming growth factor beta superfamily. Under normal conditions, GDF-15 is expressed in low concentrations in most organs and upregulated because of injury of organs su...
GDF15 Growth/differentiation factor 15 (GDF15) was first identified as Macrophage inhibitory cytokine-1 or MIC-1.[1] It is a protein belonging to the transforming growth factor beta superfamily. Under normal conditions, GDF-15 is expressed in low concentrations in most organs and upregulated because of injury of organ...
https://www.wikidoc.org/index.php/GDF15
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wikidoc
GFRA1
GFRA1 GDNF family receptor alpha-1 (GFRα1), also known as the GDNF receptor, is a protein that in humans is encoded by the GFRA1 gene. # Function Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron...
GFRA1 GDNF family receptor alpha-1 (GFRα1), also known as the GDNF receptor, is a protein that in humans is encoded by the GFRA1 gene.[1][2] # Function Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of...
https://www.wikidoc.org/index.php/GFRA1
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wikidoc
GGPS1
GGPS1 Geranylgeranyl pyrophosphate synthase is an enzyme that in humans is encoded by the GGPS1 gene. # Function This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and...
GGPS1 Geranylgeranyl pyrophosphate synthase is an enzyme that in humans is encoded by the GGPS1 gene.[1][2][3] # Function This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl dipho...
https://www.wikidoc.org/index.php/GGPS1
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wikidoc
GHITM
GHITM Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10. It is a member of the BAX inhibitor motif containing (TMBIM) family and localizes to the inner mitochond...
GHITM Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10.[1][2][3] It is a member of the BAX inhibitor motif containing (TMBIM) family and localizes to the inner...
https://www.wikidoc.org/index.php/GHITM
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wikidoc
Hertz
Hertz # Overview The hertz (symbol: Hz) is the International System of Units (SI) base unit of frequency. The definition of the hertz is based upon that for the second, namely: the hyperfine splitting in the ground state of the caesium 133 atom is exactly 9 192 631 770 hertz, \nu (hfs Cs) = 9 192 631 770 Hz. Its base ...
Hertz # Overview The hertz (symbol: Hz) is the International System of Units (SI) base unit of frequency. The definition of the hertz is based upon that for the second, namely: the hyperfine splitting in the ground state of the caesium 133 atom is exactly 9 192 631 770 hertz, <math>\nu</math> (hfs Cs) = 9 192 631 770 ...
https://www.wikidoc.org/index.php/GHz
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wikidoc
GIPC3
GIPC3 PDZ domain-containing protein GIPC3 is a protein that in humans is encoded by the GIPC3 gene. GIPC3 is a member of the GIPC (GAIP-interacting protein C terminus) gene family that also includes GIPC1 and GIPC2. The encoded protein, GIPC3, features a centrally located PDZ domain, which is flanked on each side by a ...
GIPC3 PDZ domain-containing protein GIPC3 is a protein that in humans is encoded by the GIPC3 gene.[1][2] GIPC3 is a member of the GIPC (GAIP-interacting protein C terminus) gene family that also includes GIPC1 and GIPC2.[3] The encoded protein, GIPC3, features a centrally located PDZ domain, which is flanked on each ...
https://www.wikidoc.org/index.php/GIPC3
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wikidoc
GLE1L
GLE1L Nucleoporin GLE1 is a protein that in humans is encoded by the GLE1 gene on chromosome 9. # Function This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. In...
GLE1L Nucleoporin GLE1 is a protein that in humans is encoded by the GLE1 gene on chromosome 9.[1][2][3] # Function This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA ...
https://www.wikidoc.org/index.php/GLE1L
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wikidoc
GLIS1
GLIS1 Glis1 (Glis Family Zinc Finger 1) is gene encoding a Krüppel-like protein of the same name whose locus is found on Chromosome 1p32.3. The gene is enriched in unfertilised eggs and embryos at the one cell stage and it can be used to promote direct reprogramming of somatic cells to induced pluripotent stem cells, a...
GLIS1 Glis1 (Glis Family Zinc Finger 1) is gene encoding a Krüppel-like protein of the same name whose locus is found on Chromosome 1p32.3.[1][2] The gene is enriched in unfertilised eggs and embryos at the one cell stage[3] and it can be used to promote direct reprogramming of somatic cells to induced pluripotent ste...
https://www.wikidoc.org/index.php/GLIS1
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wikidoc
GLIS2
GLIS2 GLIS family zinc finger 2 also known as GLIS2 is a human gene. # Function The protein encoded by this gene is a Kruppel-like transcription factor which functions depending on the gene and promoter context as an activator or repressor of gene transcription. GLIS2 plays a role in kidney development and neurogenesi...
GLIS2 GLIS family zinc finger 2 also known as GLIS2 is a human gene.[1][2] # Function The protein encoded by this gene is a Kruppel-like transcription factor which functions depending on the gene and promoter context as an activator or repressor of gene transcription.[2] GLIS2 plays a role in kidney development and n...
https://www.wikidoc.org/index.php/GLIS2
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wikidoc
GLRX2
GLRX2 Glutaredoxin 2 (GLRX2) is an enzyme that in humans encoded by the GLRX2 gene. GLRX2, also known as GRX2, is a glutaredoxin family protein and a thiol-disulfide oxidoreductase that maintains cellular thiol homeostasis. This gene consists of four exons and three introns, spanned 10 kilobase pairs, and localized to ...
GLRX2 Glutaredoxin 2 (GLRX2) is an enzyme that in humans encoded by the GLRX2 gene. GLRX2, also known as GRX2, is a glutaredoxin family protein and a thiol-disulfide oxidoreductase that maintains cellular thiol homeostasis. This gene consists of four exons and three introns, spanned 10 kilobase pairs, and localized to...
https://www.wikidoc.org/index.php/GLRX2
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wikidoc
GLRX5
GLRX5 Glutaredoxin 5, also known as GLRX5, is a protein which in humans is encoded by the GLRX5 gene located on chromosome 14. This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron- sulfur clusters, which are required for normal iron homeostasis. Mutation...
GLRX5 Glutaredoxin 5, also known as GLRX5, is a protein which in humans is encoded by the GLRX5 gene located on chromosome 14.[1] This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron- sulfur clusters, which are required for normal iron homeostasis. Muta...
https://www.wikidoc.org/index.php/GLRX5
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wikidoc
GRIK2
GRIK2 Glutamate ionotropic receptor kainate type subunit 2 (ionotropic glutamate receptor 6) is a protein that in humans is encoded by the GRIK2 (or GLUR6) gene. # Function This gene encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain...
GRIK2 Glutamate ionotropic receptor kainate type subunit 2 (ionotropic glutamate receptor 6) is a protein that in humans is encoded by the GRIK2 (or GLUR6) gene.[1][2][3] # Function This gene encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in...
https://www.wikidoc.org/index.php/GLUR6
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wikidoc
GLUT1
GLUT1 Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene. GLUT1 facilitates the transport of glucose across the plasma membranes of mammalian cells. This gene encodes a major gluc...
GLUT1 Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene.[1] GLUT1 facilitates the transport of glucose across the plasma membranes of mammalian cells.[2] This gene encodes a maj...
https://www.wikidoc.org/index.php/GLUT1
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wikidoc
GLUT2
GLUT2 Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. It is the principal transporter for transfer of glucose between liver and blood, and ...
GLUT2 Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. It is the principal transporter for transfer of glucose between liver and blood, and...
https://www.wikidoc.org/index.php/GLUT2
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wikidoc
GLUT3
GLUT3 Glucose transporter 3 (or GLUT3), also known as solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) is a protein that in humans is encoded by the SLC2A3 gene. GLUT3 facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT3 is most known for its specific expr...
GLUT3 Glucose transporter 3 (or GLUT3), also known as solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) is a protein that in humans is encoded by the SLC2A3 gene.[1] GLUT3 facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT3 is most known for its specific ...
https://www.wikidoc.org/index.php/GLUT3
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wikidoc
GLUT4
GLUT4 Glucose transporter type 4 (GLUT-4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). The first evi...
GLUT4 Glucose transporter type 4 (GLUT-4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). The first ev...
https://www.wikidoc.org/index.php/GLUT4
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wikidoc
GLUT8
GLUT8 GLUT8 also known as SLC2A8 is the eighth member of glucose transporter superfamily. It is characterized by the presence of two leucine residues in its N-terminal intracellular domain, which influences intracellular trafficking. # Discovery GLUT8, originally named GLUTX1, was cloned almost simultaneously by two ...
GLUT8 GLUT8 also known as SLC2A8 is the eighth member of glucose transporter superfamily.[1] It is characterized by the presence of two leucine residues in its N-terminal intracellular domain, which influences intracellular trafficking.[2] # Discovery GLUT8, originally named GLUTX1, was cloned almost simultaneously ...
https://www.wikidoc.org/index.php/GLUT8
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wikidoc
GLYAT
GLYAT Glycine-N-acyltransferase, also known as GLYAT, is an enzyme which in humans is encoded by the GLYAT gene. # Function The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria primarily in liver and kidney. The glycine N-acyltransferase enzyme is involved in the detoxi...
GLYAT Glycine-N-acyltransferase, also known as GLYAT, is an enzyme which in humans is encoded by the GLYAT gene.[1][2] # Function The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria primarily in liver and kidney. The glycine N-acyltransferase enzyme is involved in the...
https://www.wikidoc.org/index.php/GLYAT
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wikidoc
GNAI1
GNAI1 Guanine nucleotide-binding protein G(i), alpha-1 subunit is a protein that in humans is encoded by the GNAI1 gene. # Interactive pathway map Click on genes, proteins and metabolites below to link to respective articles. - ↑ The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602"....
GNAI1 Guanine nucleotide-binding protein G(i), alpha-1 subunit is a protein that in humans is encoded by the GNAI1 gene.[1][2] # Interactive pathway map Click on genes, proteins and metabolites below to link to respective articles.[§ 1] - ↑ The interactive pathway map can be edited at WikiPathways: "NicotineDopaminer...
https://www.wikidoc.org/index.php/GNAI1
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wikidoc
GOLM1
GOLM1 Golgi membrane protein 1 (GOLM1) also known as Golgi phosphoprotein 2 or Golgi membrane protein GP73 is a protein that in humans is encoded by the GOLM1 gene. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. # Function The Golgi complex plays a key role ...
GOLM1 Golgi membrane protein 1 (GOLM1) also known as Golgi phosphoprotein 2 or Golgi membrane protein GP73 is a protein that in humans is encoded by the GOLM1 gene.[1][2][3] Two alternatively spliced transcript variants encoding the same protein have been described for this gene. # Function The Golgi complex plays a...
https://www.wikidoc.org/index.php/GOLM1
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wikidoc
GOSR1
GOSR1 Golgi SNAP receptor complex member 1 is a protein that in humans is encoded by the GOSR1 gene. This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi apparatus and between Golgi compartments. This protein is considered an essential component of the...
GOSR1 Golgi SNAP receptor complex member 1 is a protein that in humans is encoded by the GOSR1 gene.[1][2][3][4] This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi apparatus and between Golgi compartments. This protein is considered an essential com...
https://www.wikidoc.org/index.php/GOSR1
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wikidoc
GPD1L
GPD1L GPD1L is a human gene. The protein encoded by this gene contains a glycerol-3-phosphate dehydrogenase (NAD+) motif and shares 72% sequence identity with GPD1. # Structure GPD1L contains the following domains: - N-terminal – NAD+ consensus binding site - a site homologous to the cardiac sodium channel SCN5A - C-t...
GPD1L GPD1L is a human gene.[1] The protein encoded by this gene contains a glycerol-3-phosphate dehydrogenase (NAD+) motif and shares 72% sequence identity with GPD1.[1] # Structure GPD1L contains the following domains:[2] - N-terminal – NAD+ consensus binding site - a site homologous to the cardiac sodium channel S...
https://www.wikidoc.org/index.php/GPD1L
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wikidoc
GPLD1
GPLD1 Phosphatidylinositol-glycan-specific phospholipase D is an enzyme that in humans is encoded by the GPLD1 gene. Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein e...
GPLD1 Phosphatidylinositol-glycan-specific phospholipase D is an enzyme that in humans is encoded by the GPLD1 gene.[1][2] Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The pr...
https://www.wikidoc.org/index.php/GPLD1
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wikidoc
GPNMB
GPNMB Transmembrane glycoprotein NMB is a protein that in humans is encoded by the GPNMB gene. Two transcript variants encoding 560 and 572 amino acid isoforms have been characterized for this gene in humans. The mouse and rat orthologues of GPNMB are known as DC-HIL and Osteoactivin (OA), respectively. GPNMB is a typ...
GPNMB Transmembrane glycoprotein NMB is a protein that in humans is encoded by the GPNMB gene.[1] Two transcript variants encoding 560 and 572 amino acid isoforms have been characterized for this gene in humans.[2] The mouse and rat orthologues of GPNMB are known as DC-HIL and Osteoactivin (OA), respectively.[2] GPNM...
https://www.wikidoc.org/index.php/GPNMB
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wikidoc
GPR17
GPR17 Uracil nucleotide/cysteinyl leukotriene receptor is a G protein-coupled receptor that in humans is encoded by the GPR17 gene located on chromosome 2 at position q21. The actual activating ligands for and some functions of this receptor are disputed. # History Initially discovered in 1998 as an Orphan receptor, i...
GPR17 Uracil nucleotide/cysteinyl leukotriene receptor is a G protein-coupled receptor that in humans is encoded by the GPR17 gene located on chromosome 2 at position q21.[1][2] The actual activating ligands for and some functions of this receptor are disputed. # History Initially discovered in 1998 as an Orphan rece...
https://www.wikidoc.org/index.php/GPR17
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wikidoc
GPR31
GPR31 G-protein coupled receptor 31 also known as 12-(S)-HETE receptor is a protein that in humans is encoded by the GPR31 gene. The human gene is located on chromosome 6q27 and encodes a G-protein coupled receptor protein composed of 319 amino acids. # Function The GPR31 receptor is most closely related in amino aci...
GPR31 G-protein coupled receptor 31 also known as 12-(S)-HETE receptor is a protein that in humans is encoded by the GPR31 gene. The human gene is located on chromosome 6q27 and encodes a G-protein coupled receptor protein composed of 319 amino acids.[1][2] # Function The GPR31 receptor is most closely related in am...
https://www.wikidoc.org/index.php/GPR31
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wikidoc
GPR32
GPR32 G protein-coupled receptor 32, also known as GPR32 or the RvD1 receptor, is a human Receptor (biochemistry) belonging to the rhodopsin-like subfamily of G protein-coupled receptors. # Gene The GPR32 was initially identified and defined by Molecular cloning in 1998 as coding for an Orphan receptor, i.e. a protein...
GPR32 G protein-coupled receptor 32, also known as GPR32 or the RvD1 receptor, is a human Receptor (biochemistry) belonging to the rhodopsin-like subfamily of G protein-coupled receptors.[1] # Gene The GPR32 was initially identified and defined by Molecular cloning in 1998 as coding for an Orphan receptor, i.e. a pro...
https://www.wikidoc.org/index.php/GPR32
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GPR35
GPR35 G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn. # Ligands ## Endogenous ligands Although GPR35 is still considered a...
GPR35 G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene.[1] Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn. # Ligands ## Endogenous ligands Although GPR35 is still consider...
https://www.wikidoc.org/index.php/GPR35
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wikidoc
GPR37
GPR37 Probable G-protein coupled receptor 37 is a protein that in humans is encoded by the GPR37 gene. # Interactions GPR37 has been shown to interact with HSPA1A and Parkin (ligase). GPR37 is a receptor for prosaposin. It was previously thought to be a receptor for head activator, a neuropeptide found in the hydra, b...
GPR37 Probable G-protein coupled receptor 37 is a protein that in humans is encoded by the GPR37 gene.[1][2] # Interactions GPR37 has been shown to interact with HSPA1A[3] and Parkin (ligase).[3][4] GPR37 is a receptor for prosaposin. It was previously thought to be a receptor for head activator, a neuropeptide found...
https://www.wikidoc.org/index.php/GPR37
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wikidoc
GPR50
GPR50 G protein-coupled receptor 50 is a protein which in humans is encoded by the GPR50 gene. # Function GPR50 is a member of the G protein-coupled receptor family of integral membrane proteins and is most closely related to the melatonin receptor. GPR50 is able to heterodimerize with both the MT1 and MT2 melatonin ...
GPR50 G protein-coupled receptor 50 is a protein which in humans is encoded by the GPR50 gene.[1][2][3] # Function GPR50 is a member of the G protein-coupled receptor family of integral membrane proteins and is most closely related to the melatonin receptor.[2] GPR50 is able to heterodimerize with both the MT1 and M...
https://www.wikidoc.org/index.php/GPR50
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wikidoc
GPR55
GPR55 G protein-coupled receptor 55 also known as GPR55 is a G protein-coupled receptor that in humans is encoded by the GPR55 gene. GPR55, along with GPR119 and GPR18, have been implicated as novel cannabinoid receptors. # History GPR55 was identified and cloned for the first time in 1999. Later it was identified by ...
GPR55 G protein-coupled receptor 55 also known as GPR55 is a G protein-coupled receptor that in humans is encoded by the GPR55 gene.[1] GPR55, along with GPR119 and GPR18, have been implicated as novel cannabinoid receptors.[2][3] # History GPR55 was identified and cloned for the first time in 1999.[4] Later it was i...
https://www.wikidoc.org/index.php/GPR55
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wikidoc
GPR56
GPR56 G protein-coupled receptor 56 also known as TM7XN1 is a protein encoded by the ADGRG1 gene. GPR56 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-...
GPR56 G protein-coupled receptor 56 also known as TM7XN1 is a protein encoded by the ADGRG1 gene.[1] GPR56 is a member of the adhesion GPCR family.[2][3] Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as...
https://www.wikidoc.org/index.php/GPR56
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wikidoc
GPR64
GPR64 G protein-coupled receptor 64 also known as HE6 is a protein encoded by the ADGRG2 gene. GPR64 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Aut...
GPR64 G protein-coupled receptor 64 also known as HE6 is a protein encoded by the ADGRG2 gene.[1] GPR64 is a member of the adhesion GPCR family.[2][3] Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as th...
https://www.wikidoc.org/index.php/GPR64
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wikidoc
GPR65
GPR65 Psychosine receptor is a G protein-coupled receptor (GPCR) protein that in humans is encoded by the GPR65 gene. GPR65 is also referred to as TDAG8. # Species, tissue, and subcellular distribution GPR65 (TDAG8) is primarily expressed in lymphoid tissues (spleen, lymph nodes, thymus, and leukocytes), and as a GPCR...
GPR65 Psychosine receptor is a G protein-coupled receptor (GPCR) protein that in humans is encoded by the GPR65 gene.[1][2] GPR65 is also referred to as TDAG8. # Species, tissue, and subcellular distribution GPR65 (TDAG8) is primarily expressed in lymphoid tissues (spleen, lymph nodes, thymus, and leukocytes),[3] and...
https://www.wikidoc.org/index.php/GPR65
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wikidoc
GPR75
GPR75 Probable G-protein coupled receptor 75 is a protein that in humans is encoded by the GPR75 gene. # Function GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand. GPR75 is currently classified as ...
GPR75 Probable G-protein coupled receptor 75 is a protein that in humans is encoded by the GPR75 gene.[1][2] # Function GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[2] GPR75 is currently clas...
https://www.wikidoc.org/index.php/GPR75
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wikidoc
GPR81
GPR81 G protein-coupled receptor 81, also known as GPR81, is a protein that in humans is encoded by the GPR81 gene. G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Lactate activates the GPR81 receptor whi...
GPR81 G protein-coupled receptor 81, also known as GPR81, is a protein that in humans is encoded by the GPR81 gene.[1][2] G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[1] Lactate activates the GPR81 re...
https://www.wikidoc.org/index.php/GPR81
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wikidoc
GPR84
GPR84 Probable G-protein coupled receptor 84 is a protein that in humans is encoded by the GPR84 gene. # Discovery GPR84 (EX33) was described practically in the same time by two groups. One was the group of Timo Wittenberger in the Zentrum fur Molekulare Neurobiologie, Hamburg, Germany (Wittenberg T. et al.) and the o...
GPR84 Probable G-protein coupled receptor 84 is a protein that in humans is encoded by the GPR84 gene.[1][2] # Discovery GPR84 (EX33) was described practically in the same time by two groups. One was the group of Timo Wittenberger in the Zentrum fur Molekulare Neurobiologie, Hamburg, Germany (Wittenberg T. et al.) an...
https://www.wikidoc.org/index.php/GPR84
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wikidoc
GPR88
GPR88 Probable G-protein coupled receptor 88 is a protein that in humans is encoded by the GPR88 gene. - Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298..mw-pa...
GPR88 Probable G-protein coupled receptor 88 is a protein that in humans is encoded by the GPR88 gene. - Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298..mw-p...
https://www.wikidoc.org/index.php/GPR88
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wikidoc
GPR97
GPR97 G-protein coupled receptor 97 also known as adhesion G protein-coupled receptor G3 (ADGRG3) is a protein that in humans is encoded by the ADGRG3 gene. GPR97 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules tha...
GPR97 G-protein coupled receptor 97 also known as adhesion G protein-coupled receptor G3 (ADGRG3) is a protein that in humans is encoded by the ADGRG3 gene.[1][2][3][4] GPR97 is a member of the adhesion GPCR family.[5][6] Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal ...
https://www.wikidoc.org/index.php/GPR97
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wikidoc
GPR98
GPR98 G protein-coupled receptor 98, also known as GPR98 or VLGR1, is a protein that in humans is encoded by the GPR98 gene. Several alternatively spliced transcripts have been described. The adhesion GPCR Very Large GPCR receptor 1 (Vlg1R1) is the largest GPCR known, with a size of 6300 amino acids and consisting of 9...
GPR98 G protein-coupled receptor 98, also known as GPR98 or VLGR1, is a protein that in humans is encoded by the GPR98 gene.[1] Several alternatively spliced transcripts have been described.[1] The adhesion GPCR Very Large GPCR receptor 1 (Vlg1R1) is the largest GPCR known, with a size of 6300 amino acids and consisti...
https://www.wikidoc.org/index.php/GPR98
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wikidoc
GPSM2
GPSM2 G-protein-signaling modulator 2, also called LGN for its 10 Leucine-Glycine-Asparagine repeats, is a protein that in humans is encoded by the GPSM2 gene. # Function Heterotrimeric G proteins transduce extracellular signals received by cell surface receptors into integrated cellular responses. GPSM2 belongs to a ...
GPSM2 G-protein-signaling modulator 2, also called LGN for its 10 Leucine-Glycine-Asparagine repeats, is a protein that in humans is encoded by the GPSM2 gene.[1][2][3] # Function Heterotrimeric G proteins transduce extracellular signals received by cell surface receptors into integrated cellular responses. GPSM2 bel...
https://www.wikidoc.org/index.php/GPSM2
441476fda7c0afbe8fd18c343399c5b7f8018842
wikidoc
GRACE
GRACE # Overview GRACE (the Global Registry of Acute Coronary Events) is a large, prospective, multinational observational study of patients hospitalized with ACS. The aim of GRACE is to improve the quality of care for patients with ACS by describing differences in, and relationships between, patient characteristics, ...
GRACE Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2] # Overview GRACE (the Global Registry of Acute Coronary Events) is a large, prospective, multinational observational study of patients hospitalized with ACS. The aim of GRACE is to improve the quality o...
https://www.wikidoc.org/index.php/GRACE
a530eb8cb460e7cbe4e34f675835c134919ecce8
wikidoc
GRB10
GRB10 Growth factor receptor-bound protein 10 also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene. # Function The product of this gene belongs to a small family of adaptor proteins that are known to interact with a number of receptor tyrosine kinases and signa...
GRB10 Growth factor receptor-bound protein 10 also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene.[1][2][3][4] # Function The product of this gene belongs to a small family of adaptor proteins that are known to interact with a number of receptor tyrosine kina...
https://www.wikidoc.org/index.php/GRB10
caa88ec72ada124c4edddbdf80a8c615a3aa48d2
wikidoc
GRB14
GRB14 Growth factor receptor-bound protein 14 is a protein that in humans is encoded by the GRB14 gene. The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding...
GRB14 Growth factor receptor-bound protein 14 is a protein that in humans is encoded by the GRB14 gene.[1][2] The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-...
https://www.wikidoc.org/index.php/GRB14
406c68e39a5b03ce08a3fce9a31860614f84ab88
wikidoc
GRIA1
GRIA1 Glutamate receptor 1 is a protein that in humans is encoded by the GRIA1 gene. # Function Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes wit...
GRIA1 Glutamate receptor 1 is a protein that in humans is encoded by the GRIA1 gene.[1][2] # Function Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein comple...
https://www.wikidoc.org/index.php/GRIA1
9a39be9d4b12be5eb559195e80c3a0a506130e3a
wikidoc
GRIA2
GRIA2 Glutamate ionotropic receptor AMPA type subunit 2 (ionotropic glutamate receptor 2) is a protein that in humans is encoded by the GRIA2 (or GLUR2) gene. # Function Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neuroph...
GRIA2 Glutamate ionotropic receptor AMPA type subunit 2 (ionotropic glutamate receptor 2) is a protein that in humans is encoded by the GRIA2 (or GLUR2) gene.[1][2][3] # Function Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of norm...
https://www.wikidoc.org/index.php/GRIA2
512f4036c86e05d401c4d850761c4e05bc59f452
wikidoc
GRIA3
GRIA3 Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. # Function Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes wit...
GRIA3 Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene.[1][2][3] # Function Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein com...
https://www.wikidoc.org/index.php/GRIA3
6d0ef62a82433714d1330afd0df7d37b0defebaf
wikidoc
GRIA4
GRIA4 Glutamate receptor 4 is a protein that in humans is encoded by the GRIA4 gene. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropiona...
GRIA4 Glutamate receptor 4 is a protein that in humans is encoded by the GRIA4 gene.[1] This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolprop...
https://www.wikidoc.org/index.php/GRIA4
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wikidoc
GRID1
GRID1 Glutamate receptor delta-1 subunit also known as GluD1 or GluRδ1 is a protein that in humans is encoded by the GRID1 gene. # Function This gene encodes a subunit of glutamate receptor ligand-gated ion channel. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system ...
GRID1 Glutamate receptor delta-1 subunit also known as GluD1 or GluRδ1 is a protein[1][2] that in humans is encoded by the GRID1 gene.[3][4] # Function This gene encodes a subunit of glutamate receptor ligand-gated ion channel. These channels mediate most of the fast excitatory synaptic transmission in the central ne...
https://www.wikidoc.org/index.php/GRID1
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wikidoc
GRID2
GRID2 Glutamate receptor, ionotropic, delta 2, also known as GluD2, GluRδ2, or δ2, is a protein that in humans is encoded by the GRID2 gene. This protein together with GluD1 belongs to the delta receptor subtype of ionotropic glutamate receptors. They possess 14–24% sequence homology with AMPA, kainate, and NMDA subuni...
GRID2 Glutamate receptor, ionotropic, delta 2, also known as GluD2, GluRδ2, or δ2, is a protein that in humans is encoded by the GRID2 gene.[1][2] This protein together with GluD1 belongs to the delta receptor subtype of ionotropic glutamate receptors. They possess 14–24% sequence homology with AMPA, kainate, and NMDA...
https://www.wikidoc.org/index.php/GRID2
b0d354bf15ab958ee816fe3d6e3de88d9c6aebc3
wikidoc
GRIK1
GRIK1 Glutamate receptor, ionotropic, kainate 1, also known as GRIK1, is a protein that in humans is encoded by the GRIK1 gene. # Function This gene encodes one of the many ionotropic glutamate receptor (GluR) subunits that function as a ligand-gated ion channel. The specific GluR subunit encoded by this gene is of th...
GRIK1 Glutamate receptor, ionotropic, kainate 1, also known as GRIK1, is a protein that in humans is encoded by the GRIK1 gene.[1] # Function This gene encodes one of the many ionotropic glutamate receptor (GluR) subunits that function as a ligand-gated ion channel. The specific GluR subunit encoded by this gene is o...
https://www.wikidoc.org/index.php/GRIK1
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wikidoc
GRIK4
GRIK4 GRIK4 (glutamate receptor, ionotropic, kainate 4) is a kainate receptor subtype belonging to the family of ligand-gated ion channels which is encoded by the GRIK4 gene. # Function This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neu...
GRIK4 GRIK4 (glutamate receptor, ionotropic, kainate 4) is a kainate receptor subtype belonging to the family of ligand-gated ion channels which is encoded by the GRIK4 gene.[1] # Function This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory...
https://www.wikidoc.org/index.php/GRIK4
72bd8dd114b1ef676b3475a3a8259c48829a89ed
wikidoc
GSDMD
GSDMD Gasdermin D (GSDMD) is a protein that in humans is encoded by the GSDMD gene on chromosome 8. It belongs the gasdermin family which is conserved among all vertebrates and comprises six members, GSDMA, GSDMB, GSDMC, GSDMD, DFNA5 and DFNB59. Members of the gasdermin family are mainly expressed in epithelial tissue...
GSDMD Gasdermin D (GSDMD) is a protein that in humans is encoded by the GSDMD gene on chromosome 8. [1] It belongs the gasdermin family which is conserved among all vertebrates and comprises six members, GSDMA, GSDMB, GSDMC, GSDMD, DFNA5 and DFNB59. Members of the gasdermin family are mainly expressed in epithelial t...
https://www.wikidoc.org/index.php/GSDMD
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wikidoc
GSK-3
GSK-3 Glycogen synthase kinase 3 is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues. First discovered in 1980 as a regulatory kinase for its namesake, Glycogen synthase, GSK-3 has since been identified as a kinase for over forty different...
GSK-3 Glycogen synthase kinase 3 is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues. First discovered in 1980 as a regulatory kinase for its namesake, Glycogen synthase,[2] GSK-3 has since been identified as a kinase for over forty diffe...
https://www.wikidoc.org/index.php/GSK-3
aa1513bdde40c9b2e2ae079d66972ba02d1cfd79
wikidoc
GSK3A
GSK3A Glycogen synthase kinase-3 alpha is an enzyme that in humans is encoded by the GSK3A gene. Glycogen synthase kinase 3-alpha EC 2.7.1.37 is a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synth...
GSK3A Glycogen synthase kinase-3 alpha is an enzyme that in humans is encoded by the GSK3A gene.[1] Glycogen synthase kinase 3-alpha EC 2.7.1.37 is a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen s...
https://www.wikidoc.org/index.php/GSK3A