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wikidoc
GSK3B
GSK3B Glycogen synthase kinase 3 beta, also known as GSK3B, is an enzyme that in humans is encoded by the GSK3B gene. In mice, the enzyme is encoded by the GSK-3β gene. Abnormal regulation and expression of GSK3β is associated with an increased susceptibility towards bipolar disorder. # Function Glycogen synthase kin...
GSK3B Glycogen synthase kinase 3 beta, also known as GSK3B, is an enzyme that in humans is encoded by the GSK3B gene.[1][2] In mice, the enzyme is encoded by the GSK-3β gene.[3] Abnormal regulation and expression of GSK3β is associated with an increased susceptibility towards bipolar disorder.[4] # Function Glycogen...
https://www.wikidoc.org/index.php/GSK3B
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wikidoc
GSTA4
GSTA4 Glutathione S-transferase A4, also known as GSTA4, is an enzyme which in humans is encoded by the GSTA4 gene. # Function Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and ...
GSTA4 Glutathione S-transferase A4, also known as GSTA4, is an enzyme which in humans is encoded by the GSTA4 gene.[1][2][3] # Function Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinog...
https://www.wikidoc.org/index.php/GSTA4
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wikidoc
GSTK1
GSTK1 Glutathione S-transferase kappa 1 (GSTK1) is an enzyme that in humans is encoded by the GSTK1 gene which is located on chromosome seven. It belongs to the superfamily of enzymes known as glutathione S-transferase (GST), which are mainly known for cellular detoxification. The GSTK1 gene consists of eight exons an...
GSTK1 Glutathione S-transferase kappa 1 (GSTK1) is an enzyme that in humans is encoded by the GSTK1 gene which is located on chromosome seven.[1] It belongs to the superfamily of enzymes known as glutathione S-transferase (GST), which are mainly known for cellular detoxification.[2] The GSTK1 gene consists of eight e...
https://www.wikidoc.org/index.php/GSTK1
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wikidoc
GSTM4
GSTM4 Glutathione S-transferase Mu 4 is an enzyme that in humans is encoded by the GSTM4 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been iden...
GSTM4 Glutathione S-transferase Mu 4 is an enzyme that in humans is encoded by the GSTM4 gene.[1][2] Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have be...
https://www.wikidoc.org/index.php/GSTM4
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wikidoc
GSTP1
GSTP1 Glutathione S-transferase P is an enzyme that in humans is encoded by the GSTP1 gene. # Function Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based o...
GSTP1 Glutathione S-transferase P is an enzyme that in humans is encoded by the GSTP1 gene.[1][2] # Function Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. ...
https://www.wikidoc.org/index.php/GSTP1
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wikidoc
GSTZ1
GSTZ1 Glutathione S-transferase Zeta 1 (also known as maleylacetoacetate isomerase) is an enzyme that in humans is encoded by the GSTZ1 gene on chromosome 14. This gene is a member of the glutathione S-transferase (GSTs) super-family, which encodes multifunctional enzymes important in the detoxification of electrophili...
GSTZ1 Glutathione S-transferase Zeta 1 (also known as maleylacetoacetate isomerase) is an enzyme that in humans is encoded by the GSTZ1 gene on chromosome 14.[1][2][3] This gene is a member of the glutathione S-transferase (GSTs) super-family, which encodes multifunctional enzymes important in the detoxification of el...
https://www.wikidoc.org/index.php/GSTZ1
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Gamma
Gamma Gamma (uppercase Γ, lowercase γ; Template:Lang-el) is the third letter of the Greek alphabet. In the system of Greek numerals it has a value of 3. It was derived from the Phoenician letter Gimel Gimel. Letters that arose from Gamma include the Roman C and G and the Cyrillic letters Ge Г and Ghe Ґ. In Modern Greek...
Gamma Template:Two other uses Template:Wiktionarypar2 Template:Table Greekletters Gamma (uppercase Γ, lowercase γ; Template:Lang-el) is the third letter of the Greek alphabet. In the system of Greek numerals it has a value of 3. It was derived from the Phoenician letter Gimel Gimel. Letters that arose from Gamma inclu...
https://www.wikidoc.org/index.php/Gamma
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wikidoc
Genes
Genes A gene is a distinct sequence of nucleotides forming part of a chromosome, the order of which determines the order of monomers in a polypeptide or nucleic acid molecule which a cell (or virus) may synthesize. # Theoretical genes Def. a "theoretical unit of heredity of living organisms ; a gene may take several v...
Genes Editor-In-Chief: Henry A. Hoff A gene is a distinct sequence of nucleotides forming part of a chromosome, the order of which determines the order of monomers in a polypeptide or nucleic acid molecule which a cell (or virus) may synthesize. # Theoretical genes Def. a "theoretical unit of heredity of living organ...
https://www.wikidoc.org/index.php/Genes
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wikidoc
Gonad
Gonad # Overview The gonad is the organ that makes gametes. The gonads in males are the testes and the gonads in females are the ovaries. The product, gametes, are haploid germ cells. For example, sperm and egg cells are gametes. Although medically the gonad term can refer to either male gonads (testicles) or female g...
Gonad Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The gonad is the organ that makes gametes. The gonads in males are the testes and the gonads in females are the ovaries. The product, gametes, are haploid germ cells. For example, sperm and egg cells are gametes. Although medically the gonad term can...
https://www.wikidoc.org/index.php/Genital_glands
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wikidoc
Genus
Genus A genus (from Ancient Greek γένος genos, "offspring, family, race, gender" - plural: genera) is a low-level taxonomic rank used in the classification of living and fossil organisms. Like almost all other taxonomic units, genera may sometimes be divided into subgenera, singular: subgenus. The largest main taxonom...
Genus Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Template:Biological classification A genus (from Ancient Greek γένος genos, "offspring, family, race, gender" - plural: genera) is a low-level taxonomic rank used in the classification of living and fossil organisms. Like almost all other taxonomic units, gener...
https://www.wikidoc.org/index.php/Genus
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wikidoc
Gland
Gland A gland is an organ in an animal's body that synthesizes a substance for release such as hormones or breast milk, often into the bloodstream (endocrine gland) or into cavities inside the body or its outer surface (exocrine gland). # Types Glands can be divided into two groups: - Endocrine glands- are glands that...
Gland Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753 A gland is an organ in an animal's body that synthesizes a substance for release such as hormones or breast milk, often into the bloodstream (endocrine gland) or into cavities inside the body or its outer surface (exocrine gland). # Types Gla...
https://www.wikidoc.org/index.php/Gland
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Gluma
Gluma Gluma Desensitizer is the most widely used product in the United States for the treatment of dental sensitivity. Its formula of 5% glutaraldehyde and 35% HEMA (hydroxyethyl methacrylate) in water is used to help control both hypersensitive dentin and reduce the incidence of post-operative sensitivity in restorati...
Gluma Gluma Desensitizer is the most widely used product in the United States for the treatment of dental sensitivity. Its formula of 5% glutaraldehyde and 35% HEMA (hydroxyethyl methacrylate) in water is used to help control both hypersensitive dentin and reduce the incidence of post-operative sensitivity in restorat...
https://www.wikidoc.org/index.php/Gluma
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wikidoc
GnRH2
GnRH2 GnRH2, also known as gonadotropin-releasing hormone II or LHRH-II. Its gene is located on human chromosome 20. Most vertebrate species possess two or three forms of gonadotropin-releasing hormone (GnRH) expressed in three distinct brain regions. Although the function of the hypothalamic form (GnRH1; common to m...
GnRH2 GnRH2, also known as gonadotropin-releasing hormone II or LHRH-II. Its gene is located on human chromosome 20.[1] Most vertebrate species possess two or three forms of gonadotropin-releasing hormone (GnRH) expressed in three distinct brain regions. Although the function of the hypothalamic form (GnRH1; common ...
https://www.wikidoc.org/index.php/GnRH2
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Gorse
Gorse Gorse (Ulex) comprises a genus of about 20 species of evergreen shrubs in the subfamily Faboideae of the pea family Fabaceae, native to western Europe and northwest Africa, with the majority of species in Iberia. Other common names for gorse include furse, whin and furze. Gorse is closely related to the brooms, a...
Gorse Gorse (Ulex) comprises a genus of about 20 species of evergreen shrubs in the subfamily Faboideae of the pea family Fabaceae, native to western Europe and northwest Africa, with the majority of species in Iberia. Other common names for gorse include furse, whin and furze. Gorse is closely related to the brooms, ...
https://www.wikidoc.org/index.php/Gorse
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wikidoc
Gp120
Gp120 # Gp120 gp120 is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons. The crystal structure of gp120 complexed to D1D2 CD4 and a neutralizing antibody Fab was solved by Peter Kwong in 1998. It is organized with an outer domain, an inne...
Gp120 Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Gp120 gp120 is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons. The crystal structure of gp120 complexed to D1D2 CD4 and a neutralizing antibody Fab was solved by Peter Kwong in...
https://www.wikidoc.org/index.php/Gp120
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wikidoc
Graft
Graft Graft or grafting may refer to: - Vein grafting, which is used in coronary artery bypass operations - Medical grafting, a surgical procedure to transplant tissue without a blood supply - Skin grafting, a type of organ transplant procedure involving skin - Grafting, where the tissues of one plant are affixed to th...
Graft Graft or grafting may refer to: - Vein grafting, which is used in coronary artery bypass operations - Medical grafting, a surgical procedure to transplant tissue without a blood supply - Skin grafting, a type of organ transplant procedure involving skin - Grafting, where the tissues of one plant are affixed to t...
https://www.wikidoc.org/index.php/Graft
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wikidoc
GroEL
GroEL GroEL belongs to the chaperonin family of molecular chaperones, and is found in a large number of bacteria. It is required for the proper folding of many proteins. To function properly, GroEL requires the lid-like cochaperonin protein complex GroES. In eukaryotes the proteins Hsp60 and Hsp10 are structurally and...
GroEL GroEL belongs to the chaperonin family of molecular chaperones, and is found in a large number of bacteria.[1] It is required for the proper folding of many proteins. To function properly, GroEL requires the lid-like cochaperonin protein complex GroES. In eukaryotes the proteins Hsp60 and Hsp10 are structurally...
https://www.wikidoc.org/index.php/GroEL
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wikidoc
GroES
GroES Heat shock 10 kDa protein 1 (Hsp10) also known as chaperonin 10 (cpn10) or early-pregnancy factor (EPF) is a protein that in humans is encoded by the HSPE1 gene. The homolog in E. coli is GroES that is a chaperonin which usually works in conjunction with GroEL. # Structure and function GroES exists as a ring-sh...
GroES Heat shock 10 kDa protein 1 (Hsp10) also known as chaperonin 10 (cpn10) or early-pregnancy factor (EPF) is a protein that in humans is encoded by the HSPE1 gene. The homolog in E. coli is GroES that is a chaperonin which usually works in conjunction with GroEL.[1] # Structure and function GroES exists as a rin...
https://www.wikidoc.org/index.php/GroES
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wikidoc
Gutka
Gutka Gutka (also spelled gutkha, guttkha, guthka) is a preparation of crushed betel nut, tobacco, and sweet or savory flavorings. It is manufactured in India and exported to a few other countries. A mild stimulant, it is sold across India in small, individual-size packets that cost between 1 and 4 rupees apiece. It is...
Gutka Gutka (also spelled gutkha, guttkha, guthka) is a preparation of crushed betel nut, tobacco, and sweet or savory flavorings. It is manufactured in India and exported to a few other countries. A mild stimulant, it is sold across India in small, individual-size packets that cost between 1 and 4 rupees apiece. It i...
https://www.wikidoc.org/index.php/Gutka
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wikidoc
Human
Human # Overview Humans, or human beings, are bipedal primates belonging to the mammalian species Homo sapiens (Latin: "wise human" or "knowing human") in the family Hominidae (the great apes). DNA evidence indicates that modern humans originated in Africa about 200,000 years ago. Compared to other species, humans hav...
Human Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] # Overview Humans, or human beings, are bipedal primates belonging to the mammalian species Homo sapiens (Latin: "wise human" or "knowing human"[2]) in the family Hominidae (the great apes).[3][4] DNA evidence indicates that modern humans originated in Africa a...
https://www.wikidoc.org/index.php/H._sapiens
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wikidoc
H2AFZ
H2AFZ Histone H2A.Z is a protein that in humans is encoded by the H2AFZ gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the...
H2AFZ Histone H2A.Z is a protein that in humans is encoded by the H2AFZ gene.[1][2] Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each...
https://www.wikidoc.org/index.php/H2AFZ
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wikidoc
H3F3A
H3F3A Histone H3.3 is a protein that in humans is encoded by the H3F3A gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 14...
H3F3A Histone H3.3 is a protein that in humans is encoded by the H3F3A gene.[1] Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximatel...
https://www.wikidoc.org/index.php/H3F3A
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wikidoc
HADHA
HADHA Trifunctional enzyme subunit alpha, mitochondrial also known as hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit is a protein that in humans is encoded by the HADHA gene. Mutations in HADHA have been associated with trifunctional protein deficiency o...
HADHA Trifunctional enzyme subunit alpha, mitochondrial also known as hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit is a protein that in humans is encoded by the HADHA gene. Mutations in HADHA have been associated with trifunctional protein deficiency ...
https://www.wikidoc.org/index.php/HADHA
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wikidoc
HADHB
HADHB Trifunctional enzyme subunit beta, mitochondrial (TP-beta) also known as 3-ketoacyl-CoA thiolase, acetyl-CoA acyltransferase, or beta-ketothiolase is an enzyme that in humans is encoded by the HADHB gene. HADHB is a subunit of the mitochondrial trifunctional protein and has thiolase activity. # Structure The HAD...
HADHB Trifunctional enzyme subunit beta, mitochondrial (TP-beta) also known as 3-ketoacyl-CoA thiolase, acetyl-CoA acyltransferase, or beta-ketothiolase is an enzyme that in humans is encoded by the HADHB gene.[1] HADHB is a subunit of the mitochondrial trifunctional protein and has thiolase activity. # Structure The...
https://www.wikidoc.org/index.php/HADHB
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wikidoc
HAND1
HAND1 Heart- and neural crest derivatives-expressed protein 1 is a protein that in humans is encoded by the HAND1 gene. A member of the HAND subclass of basic Helix-loop-helix (bHLH) transcription factors, the Heart and neural crest-derived transcript-1 (HAND1) gene is vital for the development and differentiation of t...
HAND1 Heart- and neural crest derivatives-expressed protein 1 is a protein that in humans is encoded by the HAND1 gene.[1][2][3] A member of the HAND subclass of basic Helix-loop-helix (bHLH) transcription factors, the Heart and neural crest-derived transcript-1 (HAND1) gene is vital for the development and differenti...
https://www.wikidoc.org/index.php/HAND1
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wikidoc
HAND2
HAND2 Heart- and neural crest derivatives-expressed protein 2 is a protein that in humans is encoded by the HAND2 gene. # Function The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins Ha...
HAND2 Heart- and neural crest derivatives-expressed protein 2 is a protein that in humans is encoded by the HAND2 gene.[1][2] # Function The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND prot...
https://www.wikidoc.org/index.php/HAND2
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wikidoc
HAR1F
HAR1F HAR1F is a RNA gene which is part of a human accelerated region of the human genome. HAR1F is found on the long arm of chromosome 20 and the RNA product is expressed in Cajal-Retzius cells, where it colocalizes with the protein reelin. HAR1F was identified in August 2006 when human accelerated regions (HARs) were...
HAR1F HAR1F is a RNA gene which is part of a human accelerated region of the human genome. HAR1F is found on the long arm of chromosome 20 and the RNA product is expressed in Cajal-Retzius cells, where it colocalizes with the protein reelin. HAR1F was identified in August 2006 when human accelerated regions (HARs) wer...
https://www.wikidoc.org/index.php/HAR1F
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wikidoc
HDAC1
HDAC1 Histone deacetylase 1 (HDAC1) is an enzyme that in humans is encoded by the HDAC1 gene. # Function Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/...
HDAC1 Histone deacetylase 1 (HDAC1) is an enzyme that in humans is encoded by the HDAC1 gene.[1] # Function Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/a...
https://www.wikidoc.org/index.php/HDAC1
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wikidoc
HDAC3
HDAC3 Histone deacetylase 3 is an enzyme encoded by the HDAC3 gene in both humans and mice. # Function Histones are highly alkaline proteins that package and order DNA into structural units called nucleosomes, which comprise the major protein component of chromatin. The posttranslational and enzymatically mediated lys...
HDAC3 Histone deacetylase 3 is an enzyme encoded by the HDAC3 gene in both humans and mice.[1][2][3][4] # Function Histones are highly alkaline proteins that package and order DNA into structural units called nucleosomes, which comprise the major protein component of chromatin. The posttranslational and enzymatically...
https://www.wikidoc.org/index.php/HDAC3
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wikidoc
HDAC4
HDAC4 Histone deacetylase 4, also known as HDAC4, is a protein that in humans is encoded by the HDAC4 gene. # Function Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...
HDAC4 Histone deacetylase 4, also known as HDAC4, is a protein that in humans is encoded by the HDAC4 gene.[1][2] # Function Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcri...
https://www.wikidoc.org/index.php/HDAC4
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wikidoc
HDAC6
HDAC6 Histone deacetylase 6 is an enzyme that in humans is encoded by the HDAC6 gene. # Function Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromatin structure and affects transcription. The protein encoded by ...
HDAC6 Histone deacetylase 6 is an enzyme that in humans is encoded by the HDAC6 gene.[1][2] # Function Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromatin structure and affects transcription. The protein enco...
https://www.wikidoc.org/index.php/HDAC6
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wikidoc
HDAC7
HDAC7 Histone deacetylase 7 is an enzyme that in humans is encoded by the HDAC7 gene. # Function Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. T...
HDAC7 Histone deacetylase 7 is an enzyme that in humans is encoded by the HDAC7 gene.[1][2][3] # Function Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access...
https://www.wikidoc.org/index.php/HDAC7
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wikidoc
HDAC8
HDAC8 Histone deacetylase 8 is an enzyme that in humans is encoded by the HDAC8 gene. # Function Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation / deacetylation alters chromosome structure and affects transcription factor access to DNA....
HDAC8 Histone deacetylase 8 is an enzyme that in humans is encoded by the HDAC8 gene.[1][2][3] # Function Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation / deacetylation alters chromosome structure and affects transcription factor acce...
https://www.wikidoc.org/index.php/HDAC8
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wikidoc
HECW2
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 is a protein that in humans is encoded by the HECW2 gene. # Model organisms Model organisms have been used in the study of HECW2 function. A conditional knockout mouse line called Hecw2tm1a(EUCOMM)Wtsi was generated at the Wellcome Trust Sanger Inst...
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 is a protein that in humans is encoded by the HECW2 gene.[1] # Model organisms Model organisms have been used in the study of HECW2 function. A conditional knockout mouse line called Hecw2tm1a(EUCOMM)Wtsi was generated at the Wellcome Trust Sanger ...
https://www.wikidoc.org/index.php/HECW2
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wikidoc
HERC5
HERC5 Probable E3 ubiquitin-protein ligase HERC5 is an enzyme that in humans is encoded by the HERC5 gene. This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The...
HERC5 Probable E3 ubiquitin-protein ligase HERC5 is an enzyme that in humans is encoded by the HERC5 gene.[1][2] This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cel...
https://www.wikidoc.org/index.php/HERC5
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wikidoc
HESX1
HESX1 Homeobox expressed in ES cells 1, also known as homeobox protein ANF, is a homeobox protein that in humans is encoded by the HESX1 gene. Expression of HEX1 and HESX1 marks the anterior visceral endoderm of the embryo. The AVE is an extra-embryonic tissue, key to the establishment of the anterior-posterior body ax...
HESX1 Homeobox expressed in ES cells 1, also known as homeobox protein ANF, is a homeobox protein that in humans is encoded by the HESX1 gene.[1] Expression of HEX1 and HESX1 marks the anterior visceral endoderm of the embryo. The AVE is an extra-embryonic tissue, key to the establishment of the anterior-posterior bod...
https://www.wikidoc.org/index.php/HESX1
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wikidoc
HIF1A
HIF1A Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that is encoded by the HIF1A gene. It is a basic helix-loop-helix PAS domain containing protein, and is considered as the master transcriptional regulator of cellula...
HIF1A Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that is encoded by the HIF1A gene.[1][2][3] It is a basic helix-loop-helix PAS domain containing protein, and is considered as the master transcriptional regulator ...
https://www.wikidoc.org/index.php/HIF1A
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wikidoc
HIF3A
HIF3A Hypoxia-inducible factor 3 alpha is a protein that in humans is encoded by the HIF3A gene. # Function The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3...
HIF3A Hypoxia-inducible factor 3 alpha is a protein that in humans is encoded by the HIF3A gene.[1][2][3] # Function The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). T...
https://www.wikidoc.org/index.php/HIF3A
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wikidoc
HINT2
HINT2 Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein that in humans is encoded by the HINT2 gene on chromosome 9. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression. # Structure As a member of the histidine triad nucleotide-binding (Hint)...
HINT2 Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein that in humans is encoded by the HINT2 gene on chromosome 9. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression.[1][2][3][4][5] # Structure As a member of the histidine triad nucleotid...
https://www.wikidoc.org/index.php/HINT2
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wikidoc
HIPK2
HIPK2 Homeodomain-interacting protein kinase 2 is an enzyme that in humans is encoded by the HIPK2 gene. HIPK2 can be categorized as a Serine/Threonine Protein kinase, specifically one that interacts with homeodomain transcription factors. It belongs to a family of protein kinases known as the DYRK kinases. Within thi...
HIPK2 Homeodomain-interacting protein kinase 2 is an enzyme that in humans is encoded by the HIPK2 gene.[1] HIPK2 can be categorized as a Serine/Threonine Protein kinase, specifically one that interacts with homeodomain transcription factors.[2] It belongs to a family of protein kinases known as the DYRK kinases.[3] ...
https://www.wikidoc.org/index.php/HIPK2
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wikidoc
HKDC1
HKDC1 Hexokinase domain containing 1 (HKDC1) is an enzyme which in humans is encoded by the HKDC1 gene on chromosome 10. It is a recently discovered hexokinase isoform that likely phosphorylates glucose in maternal metabolism during pregnancy. # Structure The HKDC1 gene is oriented in a head-to-tail arrangement next t...
HKDC1 Hexokinase domain containing 1 (HKDC1) is an enzyme which in humans is encoded by the HKDC1 gene on chromosome 10.[1] It is a recently discovered hexokinase isoform that likely phosphorylates glucose in maternal metabolism during pregnancy.[2][3] # Structure The HKDC1 gene is oriented in a head-to-tail arrangem...
https://www.wikidoc.org/index.php/HKDC1
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wikidoc
HLA-A
HLA-A HLA-A is a group of human leukocyte antigens (HLA) that are coded for by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility complex (MHC) antigen specific to humans. HLA-A is one of three major types of human MHC class I cell surface receptors. The others are HLA-B an...
HLA-A HLA-A is a group of human leukocyte antigens (HLA) that are coded for by the HLA-A locus, which is located at human chromosome 6p21.3.[1] HLA is a major histocompatibility complex (MHC) antigen specific to humans. HLA-A is one of three major types of human MHC class I cell surface receptors. The others are HLA-...
https://www.wikidoc.org/index.php/HLA-A
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wikidoc
HLA-B
HLA-B HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system distinguish the body's ...
HLA-B HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system distinguish the body's...
https://www.wikidoc.org/index.php/HLA-B
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wikidoc
HLA-E
HLA-E HLA class I histocompatibility antigen, alpha chain E (HLA-E) also known as MHC class I antigen E is a protein that in humans is encoded by the HLA-E gene. The human HLA-E is a non-classical MHC class I molecule that is characterized by a limited polymorphism and a lower cell surface expression than its classical...
HLA-E HLA class I histocompatibility antigen, alpha chain E (HLA-E) also known as MHC class I antigen E is a protein that in humans is encoded by the HLA-E gene.[1] The human HLA-E is a non-classical MHC class I molecule that is characterized by a limited polymorphism and a lower cell surface expression than its class...
https://www.wikidoc.org/index.php/HLA-E
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wikidoc
HLA-F
HLA-F HLA class I histocompatibility antigen, alpha chain F is a protein that in humans is encoded by the HLA-F gene. # HLA-F The Major Histocompatibility Complex (MHC) is a group of cell surface proteins that in humans is also called the Human Leukocyte Antigen (HLA) complex. These proteins are encoded by a cluster o...
HLA-F HLA class I histocompatibility antigen, alpha chain F is a protein that in humans is encoded by the HLA-F gene.[1][2] # HLA-F The Major Histocompatibility Complex (MHC) is a group of cell surface proteins that in humans is also called the Human Leukocyte Antigen (HLA) complex. These proteins are encoded by a cl...
https://www.wikidoc.org/index.php/HLA-F
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wikidoc
HLA-G
HLA-G HLA-G histocompatibility antigen, class I, G, also known as human leukocyte antigen G (HLA-G), is a protein that in humans is encoded by the HLA-G gene. HLA-G belongs to the HLA nonclassical class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-...
HLA-G HLA-G histocompatibility antigen, class I, G, also known as human leukocyte antigen G (HLA-G), is a protein that in humans is encoded by the HLA-G gene.[1] HLA-G belongs to the HLA nonclassical class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (b...
https://www.wikidoc.org/index.php/HLA-G
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wikidoc
HLA E
HLA E Major histocompatibility complex, class I, E, also known as HLA-E, is a human gene. HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restr...
HLA E Major histocompatibility complex, class I, E, also known as HLA-E, is a human gene. HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a rest...
https://www.wikidoc.org/index.php/HLA_E
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wikidoc
HMGA1
HMGA1 High-mobility group protein HMG-I/HMG-Y is a protein that in humans is encoded by the HMGA1 gene. # Function This gene encodes a non-histone chromatin protein involved in many cellular processes, including regulation of inducible gene transcription, DNA replication, heterochromatin organization, integration of ...
HMGA1 High-mobility group protein HMG-I/HMG-Y is a protein that in humans is encoded by the HMGA1 gene.[1][2] # Function This gene encodes a non-histone chromatin protein involved in many cellular processes, including regulation of inducible gene transcription, DNA replication, heterochromatin organization, integrat...
https://www.wikidoc.org/index.php/HMGA1
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wikidoc
HMGA2
HMGA2 High-mobility group AT-hook 2, also known as HMGA2, is a protein that, in humans, is encoded by the HMGA2 gene. # Function This gene encodes a protein that belongs to the non-histone chromosomal high-mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components ...
HMGA2 High-mobility group AT-hook 2, also known as HMGA2, is a protein that, in humans, is encoded by the HMGA2 gene.[1][2][3] # Function This gene encodes a protein that belongs to the non-histone chromosomal high-mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential c...
https://www.wikidoc.org/index.php/HMGA2
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wikidoc
HMGB1
HMGB1 High mobility group box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene. HMG-1 belongs to the high mobility group and contains a HMG-box domain. # Function Like the histones, HMGB1 is among the most important chromatin prote...
HMGB1 High mobility group box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene.[1][2] HMG-1 belongs to the high mobility group and contains a HMG-box domain. # Function Like the histones, HMGB1 is among the most important chromati...
https://www.wikidoc.org/index.php/HMGB1
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wikidoc
HMOX1
HMOX1 HMOX1 (heme oxygenase (decycling) 1) is a human gene that encodes for the enzyme heme oxygenase 1 (EC 1.14.99.3). Heme oxygenase mediates the first step of heme catabolism, it cleaves heme to form biliverdin. Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, carbon monoxide,...
HMOX1 HMOX1 (heme oxygenase (decycling) 1) is a human gene that encodes for the enzyme heme oxygenase 1 (EC 1.14.99.3). Heme oxygenase mediates the first step of heme catabolism, it cleaves heme to form biliverdin. Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, carbon monoxide...
https://www.wikidoc.org/index.php/HMOX1
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wikidoc
HNF1A
HNF1A HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A, is a human gene on chromosome 12. It is ubiquitously expressed in many tissues and cell types. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the ex...
HNF1A HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A, is a human gene on chromosome 12.[1][2][3] It is ubiquitously expressed in many tissues and cell types.[4] The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulat...
https://www.wikidoc.org/index.php/HNF1A
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wikidoc
HNRPD
HNRPD Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) also known as AU-rich element RNA-binding protein 1 (AUF1) is a protein that in humans is encoded by the HNRNPD gene. Alternative splicing of this gene results in four transcript variants. # Function This gene belongs to the subfamily of ubiquitously expressed ...
HNRPD Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) also known as AU-rich element RNA-binding protein 1 (AUF1) is a protein that in humans is encoded by the HNRNPD gene.[1][2] Alternative splicing of this gene results in four transcript variants. # Function This gene belongs to the subfamily of ubiquitously exp...
https://www.wikidoc.org/index.php/HNRPD
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wikidoc
HOSxP
HOSxP HOSxP is a hospital information system, including Electronic health record (EHR), in use in over 70 hospitals across Thailand. The software aims to ease the healthcare workflow of health centers, for small sanitariums to central hospitals. Before becoming HOSxP, the software was called KSK-HDBMS. Seeking a more f...
HOSxP HOSxP is a hospital information system, including Electronic health record (EHR), in use in over 70 hospitals across Thailand. The software aims to ease the healthcare workflow of health centers, for small sanitariums to central hospitals. Before becoming HOSxP, the software was called KSK-HDBMS. Seeking a more ...
https://www.wikidoc.org/index.php/HOSxP
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wikidoc
HOT-2
HOT-2 HOT-2, or 2,5-dimethoxy-4-(β-ethylthio)-N-hydroxyphenethylamine is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book PIHKAL. # Chemistry HOT-2's full chemical name is 2-[4-(2-ethylthio)-2,5-dimethoxyphenyl-N-hydroxyethanamine. It ha...
HOT-2 HOT-2, or 2,5-dimethoxy-4-(β-ethylthio)-N-hydroxyphenethylamine is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book PIHKAL. # Chemistry HOT-2's full chemical name is 2-[4-(2-ethylthio)-2,5-dimethoxyphenyl-N-hydroxyethanamine. It h...
https://www.wikidoc.org/index.php/HOT-2
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wikidoc
HOT-7
HOT-7 HOT-7, or 2,5-dimethoxy-4-(β-propylthio)-N-hydroxyphenethylamine, is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book, PIHKAL. # Chemistry HOT-7's full chemical name is 2-[4-(2-propylthio)-2,5-dimethoxyphenyl-N-hydroxyethanamine. I...
HOT-7 HOT-7, or 2,5-dimethoxy-4-(β-propylthio)-N-hydroxyphenethylamine, is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book, PIHKAL. # Chemistry HOT-7's full chemical name is 2-[4-(2-propylthio)-2,5-dimethoxyphenyl-N-hydroxyethanamine. ...
https://www.wikidoc.org/index.php/HOT-7
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wikidoc
HOXA2
HOXA2 Homeobox protein Hox-A2 is a protein that in humans is encoded by the HOXA2 gene. # Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporall...
HOXA2 Homeobox protein Hox-A2 is a protein that in humans is encoded by the HOXA2 gene.[1] # Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and tempo...
https://www.wikidoc.org/index.php/HOXA2
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wikidoc
HOXA3
HOXA3 Homeobox protein Hox-A3 is a protein that in humans is encoded by the HOXA3 gene. # Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporall...
HOXA3 Homeobox protein Hox-A3 is a protein that in humans is encoded by the HOXA3 gene.[1][2][3] # Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and...
https://www.wikidoc.org/index.php/HOXA3
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wikidoc
HOXA5
HOXA5 Homeobox protein Hox-A5 is a protein that in humans is encoded by the HOXA5 gene. # Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporall...
HOXA5 Homeobox protein Hox-A5 is a protein that in humans is encoded by the HOXA5 gene.[1][2][3] # Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and...
https://www.wikidoc.org/index.php/HOXA5
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wikidoc
HOXA6
HOXA6 Homeobox protein Hox-A6 is a protein that in humans is encoded by the HOXA6 gene. # Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporall...
HOXA6 Homeobox protein Hox-A6 is a protein that in humans is encoded by the HOXA6 gene.[1][2][3] # Function In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and...
https://www.wikidoc.org/index.php/HOXA6
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wikidoc
HOXA9
HOXA9 Homeobox protein Hox-A9 is a protein that in humans is encoded by the HOXA9 gene. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated ...
HOXA9 Homeobox protein Hox-A9 is a protein that in humans is encoded by the HOXA9 gene.[1][2] In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally reg...
https://www.wikidoc.org/index.php/HOXA9
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wikidoc
HOXB6
HOXB6 Homeobox protein Hox-B6 is a protein that in humans is encoded by the HOXB6 gene. # Function This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a seq...
HOXB6 Homeobox protein Hox-B6 is a protein that in humans is encoded by the HOXB6 gene.[1][2][3] # Function This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein function...
https://www.wikidoc.org/index.php/HOXB6
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wikidoc
HOXB7
HOXB7 Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene. # Function This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions ...
HOXB7 Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.[1][2] # Function This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein fun...
https://www.wikidoc.org/index.php/HOXB7
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wikidoc
HOXB8
HOXB8 Homeobox protein Hox-B8 is a protein that in humans is encoded by the HOXB8 gene. # Function This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of Homeobox B genes located on chromosome 17. The encoded protein functions ...
HOXB8 Homeobox protein Hox-B8 is a protein that in humans is encoded by the HOXB8 gene.[1][2][3] # Function This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of Homeobox B genes located on chromosome 17. The encoded protein ...
https://www.wikidoc.org/index.php/HOXB8
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wikidoc
KMT2A
KMT2A Histone-lysine N-methyltransferase 2A also known as acute lymphoblastic leukemia 1 (ALL-1), myeloid/lymphoid or mixed-lineage leukemia 1 (MLL1), or zinc finger protein HRX (HRX) is an enzyme that in humans is encoded by the KMT2A gene. MLL1 is a histone methyltransferase deemed a positive global regulator of gene...
KMT2A Histone-lysine N-methyltransferase 2A also known as acute lymphoblastic leukemia 1 (ALL-1), myeloid/lymphoid or mixed-lineage leukemia 1 (MLL1), or zinc finger protein HRX (HRX) is an enzyme that in humans is encoded by the KMT2A gene.[1] MLL1 is a histone methyltransferase deemed a positive global regulator of ...
https://www.wikidoc.org/index.php/HRX
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wikidoc
HSPA8
HSPA8 Heat shock 70 kDa protein 8 also known as heat shock cognate 71 kDa protein or Hsc70 or Hsp73 is a heat shock protein that in humans is encoded by the HSPA8 gene on chromosome 11. As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated and mi...
HSPA8 Heat shock 70 kDa protein 8 also known as heat shock cognate 71 kDa protein or Hsc70 or Hsp73 is a heat shock protein that in humans is encoded by the HSPA8 gene on chromosome 11.[1] As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated an...
https://www.wikidoc.org/index.php/HSPA8
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wikidoc
HSPB6
HSPB6 Heat shock protein beta-6 is a protein that in humans is encoded by the HSPB6 gene. HSPB6 also known as hsp20 is a 17-kDa member of the small heat shock family of proteins. HSPB6 was first identified in 1994 when it was isolated from rat and human skeletal muscle as a complex with HSPB1 (also known as HSP27) and ...
HSPB6 Heat shock protein beta-6 is a protein that in humans is encoded by the HSPB6 gene.[1][2][3] HSPB6 also known as hsp20 is a 17-kDa member of the small heat shock family of proteins. HSPB6 was first identified in 1994 when it was isolated from rat and human skeletal muscle as a complex with HSPB1 (also known as H...
https://www.wikidoc.org/index.php/HSPB6
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wikidoc
HTRA1
HTRA1 Serine protease HTRA1 is an enzyme that in humans is encoded by the HTRA1 gene. The HTRA1 protein is composed of four distinct protein domains. They are from amino-terminus to carboxyl-terminus an Insulin-like growth factor binding domain, a kazal domain, a trypsin-like peptidase domain and a PDZ domain. This gen...
HTRA1 Serine protease HTRA1 is an enzyme that in humans is encoded by the HTRA1 gene.[1][2] The HTRA1 protein is composed of four distinct protein domains. They are from amino-terminus to carboxyl-terminus an Insulin-like growth factor binding domain, a kazal domain, a trypsin-like peptidase domain and a PDZ domain. T...
https://www.wikidoc.org/index.php/HTRA1
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wikidoc
HVCN1
HVCN1 Voltage-gated hydrogen channel 1 is a protein that in humans is encoded by the HVCN1 gene. Voltage-gated hydrogen channel 1 is a voltage-gated proton channel that has been shown to allow proton transport into phagosomes and out of many types of cells including spermatozoa, electrically excitable cells and respir...
HVCN1 Voltage-gated hydrogen channel 1 is a protein that in humans is encoded by the HVCN1 gene. Voltage-gated hydrogen channel 1 is a voltage-gated proton channel that has been shown to allow proton transport into phagosomes[1][2] and out of many types of cells including spermatozoa, electrically excitable cells and...
https://www.wikidoc.org/index.php/HVCN1
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wikidoc
HYAL2
HYAL2 Hyaluronidase-2 is an enzyme that in humans is encoded by the HYAL2 gene. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell pr...
HYAL2 Hyaluronidase-2 is an enzyme that in humans is encoded by the HYAL2 gene.[1][2][3] This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved ...
https://www.wikidoc.org/index.php/HYAL2
4aa2f36da4423f2eaf0704908d7f3c8a58b59a22
wikidoc
Heave
Heave Synonyms and Keywords: lift, parasternal heave, parasternal lift, left ventricular impulse, LV impulse # Overview A heave is felt as an upward displacement of the chest against the hand during palpation of the precordium. Heaves are best felt with the heel of the hand at the sternal border. # Physical Examinati...
Heave Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Synonyms and Keywords: lift, parasternal heave, parasternal lift, left ventricular impulse, LV impulse # Overview A heave is felt as an upward displacement of the chest against the hand during palpation of the precordium. Heaves are best felt with the heel of t...
https://www.wikidoc.org/index.php/Heave
ade36e27a47ae484fe00c71af02f79a828a4de4d
wikidoc
Hemin
Hemin # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pa...
Hemin Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Adeel Jamil, M.D. [2] # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an edu...
https://www.wikidoc.org/index.php/Hematin
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wikidoc
Henna
Henna Henna or Hina (Lawsonia inermis, syn. L. alba) is a flowering plant, the sole species in the genus Lawsonia in the family Lythraceae. It is native to tropical and subtropical regions of Africa, southern Asia, and northern Australasia in semi-arid zones. Henna is a tall shrub or small tree, 2–6 m high. It is glab...
Henna Template:Wiktionarypar Template:Two other uses Henna or Hina (Lawsonia inermis, syn. L. alba) is a flowering plant, the sole species in the genus Lawsonia in the family Lythraceae. It is native to tropical and subtropical regions of Africa, southern Asia, and northern Australasia in semi-arid zones. Henna is a t...
https://www.wikidoc.org/index.php/Henna
eda9e0ffe5042e6c9e8b0c865fa95d60c60bdb7c
wikidoc
Liver
Liver # Overview The liver is an organ present in vertebrates and some other animals. It plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, and detoxification. This organ also is the largest gland in the hu...
Liver Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Template:Infobox Anatomy The liver is an organ present in vertebrates and some other animals. It plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein ...
https://www.wikidoc.org/index.php/Hepatic
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wikidoc
Her 3
Her 3 This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. How...
Her 3 This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. Ho...
https://www.wikidoc.org/index.php/Her_3
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wikidoc
Hilum
Hilum # Overview A hilum (formerly called a hilus) is a depression or pit at the part of an organ where structures such as blood vessels and nerves enter. Medial depression for blood vessels and ureter to enter kidney chamber The adjective form is "hilar", and the plural is "hila". # Examples - the hilum of kidney (a...
Hilum Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview A hilum (formerly called a hilus) is a depression or pit at the part of an organ where structures such as blood vessels and nerves enter. Medial depression for blood vessels and ureter to enter kidney chamber The adjective form is "hilar", and the pl...
https://www.wikidoc.org/index.php/Hilar
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wikidoc
HslVU
HslVU The heat shock proteins hslV and hslU (also known as clpQ and clpY respectively) are expressed in many bacteria such as E. coli in response to cell stress. The hslV protein is a protease and the hslU protein is an ATPase; the two form a symmetric assembly of four stacked rings, consisting of an hslV dodecamer bou...
HslVU The heat shock proteins hslV and hslU (also known as clpQ and clpY respectively[1]) are expressed in many bacteria such as E. coli in response to cell stress. The hslV protein is a protease and the hslU protein is an ATPase; the two form a symmetric assembly of four stacked rings, consisting of an hslV dodecamer...
https://www.wikidoc.org/index.php/HslVU
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wikidoc
Hsp27
Hsp27 Heat shock protein 27 (Hsp27) also known as heat shock protein beta-1 (HSPB1) is a protein that in humans is encoded by the HSPB1 gene. Hsp27 is a chaperone of the sHsp (small heat shock protein) group among ubiquitin, α-crystallin, Hsp20 and others. The common functions of sHsps are chaperone activity, thermotol...
Hsp27 Heat shock protein 27 (Hsp27) also known as heat shock protein beta-1 (HSPB1) is a protein that in humans is encoded by the HSPB1 gene.[1][2] Hsp27 is a chaperone of the sHsp (small heat shock protein) group among ubiquitin, α-crystallin, Hsp20 and others. The common functions of sHsps are chaperone activity, th...
https://www.wikidoc.org/index.php/Hsp27
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wikidoc
Hymen
Hymen # Overview The hymen (also called maidenhead) is a fold of mucous membrane which surrounds or partially covers the external vaginal opening. Its name comes from the ancient greek for "hymenaeus," which means "vaginal-flap." It was also the name for the Greek god of marriage, later also the Greek god of membranes...
Hymen Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview The hymen (also called maidenhead)[1] is a fold of mucous membrane which surrounds or partially covers the external vaginal opening. Its name comes from the ancient greek for "hymenaeus," which means "vaginal-flap." It was also the name for the Greek...
https://www.wikidoc.org/index.php/Hymen
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wikidoc
Hyrax
Hyrax A hyrax (from Greek Template:Polytonic 'shrewmouse'; Afrikaans: klipdassie, from Dutch: klipdas 'rockbadger') is any of four species of fairly small, thickset, herbivorous mammals in the order Hyracoidea. They live in Africa and the Middle East. Hyraxes are well-furred rotund creatures with a mere stump for a tai...
Hyrax A hyrax (from Greek Template:Polytonic 'shrewmouse'; Afrikaans: klipdassie, from Dutch: klipdas 'rockbadger') is any of four species of fairly small, thickset, herbivorous mammals in the order Hyracoidea. They live in Africa and the Middle East. Hyraxes are well-furred rotund creatures with a mere stump for a ta...
https://www.wikidoc.org/index.php/Hyrax
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wikidoc
ICAM2
ICAM2 Intercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a human gene, and the protein resulting from it. # Protein structure The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane gl...
ICAM2 Intercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a human gene, and the protein resulting from it. # Protein structure The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane g...
https://www.wikidoc.org/index.php/ICAM2
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wikidoc
ICAM4
ICAM4 The LW blood system was first described by Landsteiner and Wiener in 1940. It was often confused with the Rh system, not becoming a separate antigen system until 1982. The LW and RhD antigens are genetically independent though they are phenotypically related and the LW antigen is expressed more strongly on RhD po...
ICAM4 The LW blood system was first described by Landsteiner and Wiener in 1940.[1] It was often confused with the Rh system, not becoming a separate antigen system until 1982. The LW and RhD antigens are genetically independent though they are phenotypically related and the LW antigen is expressed more strongly on Rh...
https://www.wikidoc.org/index.php/ICAM4
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wikidoc
IDH3A
IDH3A Isocitrate dehydrogenase subunit alpha, mitochondrial (IDH3α) is an enzyme that in humans is encoded by the IDH3A gene. Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the ele...
IDH3A Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3α) is an enzyme that in humans is encoded by the IDH3A gene.[1][2] Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+...
https://www.wikidoc.org/index.php/IDH3A
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wikidoc
IDH3B
IDH3B Isocitrate dehydrogenase subunit beta, mitochondrial is an enzyme that in humans is encoded by the IDH3B gene. Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acc...
IDH3B Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial is an enzyme that in humans is encoded by the IDH3B gene.[1][2] Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the ...
https://www.wikidoc.org/index.php/IDH3B
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wikidoc
IDH3G
IDH3G Isocitrate dehydrogenase subunit gamma, mitochondrial is an enzyme that in humans is encoded by the IDH3G gene. Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron ac...
IDH3G Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial is an enzyme that in humans is encoded by the IDH3G gene.[1][2] Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the...
https://www.wikidoc.org/index.php/IDH3G
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wikidoc
IFFO1
IFFO1 Intermediate filament family orphan 1 is a protein that in humans is encoded by the IFFO1 gene. IFFO1 has uncharacterized function and a weight of 61.98 kDa. IFFO1 proteins play an important role in the cytoskeleton and the nuclear envelope of most eukaryotic cell types. # Gene IFFO in human is located on the mi...
IFFO1 Intermediate filament family orphan 1 is a protein that in humans is encoded by the IFFO1 gene. IFFO1 has uncharacterized function and a weight of 61.98 kDa.[1] IFFO1 proteins play an important role in the cytoskeleton and the nuclear envelope of most eukaryotic cell types.[2] # Gene IFFO in human is located on...
https://www.wikidoc.org/index.php/IFFO1
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wikidoc
IFNA2
IFNA2 Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene. # Protein family Human interferon alpha-2 (IFNα2) is a cytokine belonging to the family of type I IFNs. IFNα2 is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. The first description...
IFNA2 Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene.[1] # Protein family Human interferon alpha-2 (IFNα2) is a cytokine belonging to the family of type I IFNs. IFNα2 is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. The first descrip...
https://www.wikidoc.org/index.php/IFNA2
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wikidoc
IFRD1
IFRD1 Interferon-related developmental regulator 1 is a protein that in humans is encoded by the IFRD1 gene. The gene is expressed mostly in neutrophils, skeletal and cardiac muscle, brain, pancreas. The rat and the mouse homolog genes of interferon-related developmental regulator 1 gene (and their proteins) are also k...
IFRD1 Interferon-related developmental regulator 1 is a protein that in humans is encoded by the IFRD1 gene.[1][2] The gene is expressed mostly in neutrophils, skeletal and cardiac muscle, brain, pancreas.[1][2] The rat and the mouse homolog genes of interferon-related developmental regulator 1 gene (and their protein...
https://www.wikidoc.org/index.php/IFRD1
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wikidoc
IFT20
IFT20 Intraflagellar transport protein 20 homolog is a protein that in humans is encoded by the IFT20 gene. The gene is composed of 6 exons and is located on human chromosome 17p11.1. This gene is expressed in human brain, lung, kidney and pancreas, and lower expression were also detected in human placenta, liver, thym...
IFT20 Intraflagellar transport protein 20 homolog is a protein that in humans is encoded by the IFT20 gene.[1] The gene is composed of 6 exons and is located on human chromosome 17p11.1. This gene is expressed in human brain, lung, kidney and pancreas, and lower expression were also detected in human placenta, liver, ...
https://www.wikidoc.org/index.php/IFT20
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wikidoc
IFT80
IFT80 Intraflagellar transport protein 80 homolog (IFT80), also known as WD repeat-containing protein 56, is a protein that in humans is encoded by the IFT80 gene. # Function IFT80 is part of the intraflagellar transport complex B and is necessary for the function of motile and sensory cilia. # Clinical significance ...
IFT80 Intraflagellar transport protein 80 homolog (IFT80), also known as WD repeat-containing protein 56, is a protein that in humans is encoded by the IFT80 gene.[1][2] # Function IFT80 is part of the intraflagellar transport complex B and is necessary for the function of motile and sensory cilia.[1] # Clinical sig...
https://www.wikidoc.org/index.php/IFT80
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wikidoc
IGBP1
IGBP1 Immunoglobulin-binding protein 1 is a protein that in humans is encoded by the IGBP1 gene. # Function The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through...
IGBP1 Immunoglobulin-binding protein 1 is a protein that in humans is encoded by the IGBP1 gene.[1][2] # Function The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction ...
https://www.wikidoc.org/index.php/IGBP1
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wikidoc
IGSF1
IGSF1 Immunoglobulin superfamily, member 1 is a plasma membrane glycoprotein encoded by the IGSF1 gene, which maps to the X chromosome in humans and other mammalian species. # Function IGSF1's function in normal cells is unresolved. The protein is a member of the immunoglobulin (Ig) superfamily. It was predicted to c...
IGSF1 Immunoglobulin superfamily, member 1[1] is a plasma membrane glycoprotein encoded by the IGSF1 gene,[2][3][4] which maps to the X chromosome in humans and other mammalian species. # Function IGSF1's function in normal cells is unresolved. The protein is a member of the immunoglobulin (Ig) superfamily. It was p...
https://www.wikidoc.org/index.php/IGSF1
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wikidoc
IKBKE
IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon also known as I-kappa-B kinase epsilon or IKK-epsilon is an enzyme that in humans is encoded by the IKBKE gene. # Interactions IKBKE has been shown to interact with TANK. # Function Serine/threonine kinase that plays an essential role in regulating inf...
IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon also known as I-kappa-B kinase epsilon or IKK-epsilon is an enzyme that in humans is encoded by the IKBKE gene.[1][2][3] # Interactions IKBKE has been shown to interact with TANK.[4] # Function Serine/threonine kinase that plays an essential role in r...
https://www.wikidoc.org/index.php/IKBKE
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wikidoc
IKBKG
IKBKG NF-kappa-B essential modulator (NEMO) also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ) is a protein that in humans is encoded by the IKBKG gene. NEMO is a subunit of the IκB kinase complex that activates NF-κB. The human gene for IKBKG is located on chromosome Xq28. Multiple transcr...
IKBKG NF-kappa-B essential modulator (NEMO) also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ) is a protein that in humans is encoded by the IKBKG gene. NEMO is a subunit of the IκB kinase complex that activates NF-κB.[1] The human gene for IKBKG is located on chromosome Xq28.[2] Multiple ...
https://www.wikidoc.org/index.php/IKBKG
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wikidoc
IKZF3
IKZF3 Zinc finger protein Aiolos also known as Ikaros family zinc finger protein 3 is a protein that in humans is encoded by the IKZF3 gene. # Function This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific tr...
IKZF3 Zinc finger protein Aiolos also known as Ikaros family zinc finger protein 3 is a protein that in humans is encoded by the IKZF3 gene.[1][2][3] # Function This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-s...
https://www.wikidoc.org/index.php/IKZF3
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wikidoc
IL17A
IL17A Interleukin-17A is a protein that in humans is encoded by the IL17A gene. # Function The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression ...
IL17A Interleukin-17A is a protein that in humans is encoded by the IL17A gene.[1][2] # Function The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expr...
https://www.wikidoc.org/index.php/IL17A
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wikidoc
IL2RA
IL2RA Interleukin-2 receptor alpha chain (also called CD25) is a protein that in humans is encoded by the IL2RA gene. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result i...
IL2RA Interleukin-2 receptor alpha chain (also called CD25) is a protein that in humans is encoded by the IL2RA gene.[1] The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) resu...
https://www.wikidoc.org/index.php/IL2RA
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wikidoc
IL2RB
IL2RB Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene. Also known as CD122; IL15RB; P70-75. # Function The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity fo...
IL2RB Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene.[1] Also known as CD122; IL15RB; P70-75.[1] # Function The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affi...
https://www.wikidoc.org/index.php/IL2RB
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wikidoc
IMViC
IMViC The IMViC tests are a group of individual tests used in microbiology lab testing to identify an organism. These four tests include: - Indole production - Methyl Red test - Voges-Proskauer test - Citrate Production These IMViC tests are useful for differentiating the the family Enterobacteriaceae, especially when ...
IMViC The IMViC tests are a group of individual tests used in microbiology lab testing to identify an organism. These four tests include: - Indole production - Methyl Red test - Voges-Proskauer test - Citrate Production These IMViC tests are useful for differentiating the the family Enterobacteriaceae, especially when...
https://www.wikidoc.org/index.php/IMViC
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wikidoc
INAVA
INAVA INAVA, sometimes referred to as hypothetical protein LOC55765, is a protein of unknown function that in humans is encoded by the INAVA gene. Less common gene aliases include FLJ10901 and MGC125608. # Gene ## Location In humans, INAVA is located on the long arm of chromosome 1 at locus 1q32.1. It spans from 200,...
INAVA INAVA, sometimes referred to as hypothetical protein LOC55765, is a protein of unknown function that in humans is encoded by the INAVA gene.[1] Less common gene aliases include FLJ10901 and MGC125608. # Gene ## Location In humans, INAVA is located on the long arm of chromosome 1 at locus 1q32.1. It spans from ...
https://www.wikidoc.org/index.php/INAVA