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wikidoc
INHBB
INHBB Inhibin, beta B, also known as INHBB, is a protein which in humans is encoded by the INHBB gene. INHBB is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects. # Function ## Inhibin Inhibins are heterodimeric glycoproteins composed of an α subunit (INHA) and ...
INHBB Inhibin, beta B, also known as INHBB, is a protein which in humans is encoded by the INHBB gene.[1][2] INHBB is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects. # Function ## Inhibin Inhibins are heterodimeric glycoproteins composed of an α subunit (INH...
https://www.wikidoc.org/index.php/INHBB
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wikidoc
INPP1
INPP1 Inositol polyphosphate 1-phosphatase is an enzyme that, in humans, is encoded by the INPP1 gene. INPP1 encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from th...
INPP1 Inositol polyphosphate 1-phosphatase is an enzyme that, in humans, is encoded by the INPP1 gene.[1][2] INPP1 encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring ...
https://www.wikidoc.org/index.php/INPP1
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wikidoc
IPLEX
IPLEX IPLEX (mecasermin rinfabate injection) is a drug developed by INSMED corporation for the treatment of growth failure in children with severe primary IGF-I deficiency (Primary IGFD) or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to GH. Due to a patent settlement, IPLEX is bei...
IPLEX Template:Primarysources IPLEX (mecasermin rinfabate [rDNA origin] injection) is a drug developed by INSMED corporation for the treatment of growth failure in children with severe primary IGF-I deficiency (Primary IGFD) or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to GH. Du...
https://www.wikidoc.org/index.php/IPLEX
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wikidoc
KPNB1
KPNB1 Lua error in Module:Redirect at line 65: could not parse redirect on page "IPOB". Importin subunit beta-1 is a protein that in humans is encoded by the KPNB1 gene. # Function Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear en...
KPNB1 Lua error in Module:Redirect at line 65: could not parse redirect on page "IPOB". Importin subunit beta-1 is a protein that in humans is encoded by the KPNB1 gene.[1][2] # Function Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuc...
https://www.wikidoc.org/index.php/IPOB
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wikidoc
IRAK4
IRAK4 IRAK-4 (interleukin-1 receptor-associated kinase 4), in the IRAK family, is a protein kinase involved in signaling innate immune responses from Toll-like receptors. It also supports signaling from T-cell receptors. IRAK4 contains domain structures which are similar to those of IRAK1, IRAK2, IRAKM and Pelle. IRAK4...
IRAK4 IRAK-4 (interleukin-1 receptor-associated kinase 4), in the IRAK family, is a protein kinase involved in signaling innate immune responses from Toll-like receptors. It also supports signaling from T-cell receptors. IRAK4 contains domain structures which are similar to those of IRAK1, IRAK2, IRAKM and Pelle. IRAK...
https://www.wikidoc.org/index.php/IRAK4
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wikidoc
ISFET
ISFET # Overview An ISFET is an ion-sensitive field effect transistor used to measure ion concentrations in solution; when the ion concentration (such as pH) changes, the current through the transistor will change accordingly. Here, the solution is used as the gate electrode. A voltage between substrate and oxide surf...
ISFET # Overview An ISFET is an ion-sensitive field effect transistor used to measure ion concentrations in solution; when the ion concentration (such as pH) changes, the current through the transistor will change accordingly. Here, the solution is used as the gate electrode. A voltage between substrate and oxide surf...
https://www.wikidoc.org/index.php/ISFET
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wikidoc
ISG15
ISG15 Interferon-stimulated gene 15 (ISG15) is a 17 kDA secreted protein that in humans is encoded by the ISG15 gene. The main cellular function of the protein is ISGylation, its covalent addition to cytoplasmic and nuclear proteins, similar to ubiquitination. In addition, ISG15 has anti-viral activity. ISG15 shares se...
ISG15 Interferon-stimulated gene 15 (ISG15) is a 17 kDA secreted protein that in humans is encoded by the ISG15 gene.[1][2] The main cellular function of the protein is ISGylation, its covalent addition to cytoplasmic and nuclear proteins, similar to ubiquitination. In addition, ISG15 has anti-viral activity.[3] ISG15...
https://www.wikidoc.org/index.php/ISG15
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wikidoc
iSOFT
iSOFT iSOFT is an international supplier of software applications for the healthcare sector. Its products are used by more than 8,000 organisations in 27 countries for managing patient information and healthcare services. The company, which has its headquarters in England, is heavily involved in the UK National Health ...
iSOFT Template:Infobox Company iSOFT is an international supplier of software applications for the healthcare sector. Its products are used by more than 8,000 organisations in 27 countries for managing patient information and healthcare services. The company, which has its headquarters in England, is heavily involved ...
https://www.wikidoc.org/index.php/ISOFT
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wikidoc
ITFG3
ITFG3 Protein ITFG3 also known as family with sequence similarity 234 member A (FAM234A) is a protein that in humans is encoded by the ITFG3 gene. Here, the gene is explored as encoded by mRNA found in Homo sapiens. The FAM234A gene is conserved in mice, rats, chickens, zebrafish, dogs, cows, frogs, chimpanzees, and ...
ITFG3 Protein ITFG3 also known as family with sequence similarity 234 member A (FAM234A) is a protein that in humans is encoded by the ITFG3 gene.[1][2] Here, the gene is explored as encoded by mRNA found in Homo sapiens. The FAM234A gene is conserved in mice, rats, chickens, zebrafish, dogs, cows, frogs, chimpanzee...
https://www.wikidoc.org/index.php/ITFG3
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wikidoc
ITGA7
ITGA7 Alpha-7 integrin is a protein that in humans is encoded by the ITGA7 gene. Alpha-7 integrin is critical for modulating cell-matrix interactions. Alpha-7 integrin is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Z-disc and costamere structures. Mutations in ITGA7 hav...
ITGA7 Alpha-7 integrin is a protein that in humans is encoded by the ITGA7 gene.[1][2] Alpha-7 integrin is critical for modulating cell-matrix interactions. Alpha-7 integrin is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Z-disc and costamere structures. Mutations in IT...
https://www.wikidoc.org/index.php/ITGA7
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wikidoc
ITGA9
ITGA9 Integrin alpha-9 is a protein that in humans is encoded by the ITGA9 gene. # Function This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, whe...
ITGA9 Integrin alpha-9 is a protein that in humans is encoded by the ITGA9 gene.[1][2][3] # Function This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this...
https://www.wikidoc.org/index.php/ITGA9
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wikidoc
ITGAV
ITGAV Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. # Function ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light c...
ITGAV Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene.[1] # Function ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and lig...
https://www.wikidoc.org/index.php/ITGAV
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wikidoc
ITGB4
ITGB4 Integrin, beta 4 (ITGB4) also known as CD104 (Cluster of Differentiation 104), is a human gene. # Function Integrins are heterodimers composed of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes t...
ITGB4 Integrin, beta 4 (ITGB4) also known as CD104 (Cluster of Differentiation 104), is a human gene.[1] # Function Integrins are heterodimers composed of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complex...
https://www.wikidoc.org/index.php/ITGB4
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wikidoc
ITGB8
ITGB8 Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene. # Function This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodi...
ITGB8 Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene.[1] # Function This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a hete...
https://www.wikidoc.org/index.php/ITGB8
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wikidoc
ITM2A
ITM2A Integral membrane protein 2A is a protein that in humans is encoded by the ITM2A gene. # Function The protein encoded by this gene is involved in osteo- and chondrogenic cellular differentiation (the cells which are responsible for the development of bone and cartilage respectively). ITM2A is also involved in ...
ITM2A Integral membrane protein 2A is a protein that in humans is encoded by the ITM2A gene.[1][2][3][4] # Function The protein encoded by this gene is involved in osteo- and chondrogenic cellular differentiation (the cells which are responsible for the development of bone and cartilage respectively).[2] ITM2A is a...
https://www.wikidoc.org/index.php/ITM2A
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wikidoc
ITPKA
ITPKA Inositol-trisphosphate 3-kinase A is an enzyme that in humans is encoded by the ITPKA gene. # Structure ITPKA is one of three inositol-trisphosphate 3-kinase (ITP3K) genes in humans. ITP3K proteins regulate inositol phosphate metabolism by phosphorylation of the second messenger inositol 1,4,5-trisphosphate to p...
ITPKA Inositol-trisphosphate 3-kinase A is an enzyme that in humans is encoded by the ITPKA gene.[1][2][3] # Structure ITPKA is one of three inositol-trisphosphate 3-kinase (ITP3K) genes in humans. ITP3K proteins regulate inositol phosphate metabolism by phosphorylation of the second messenger inositol 1,4,5-trisphos...
https://www.wikidoc.org/index.php/ITPKA
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wikidoc
ITPKC
ITPKC ITPKC is one of 3 human genes that encode for an Inositol-trisphosphate 3-kinase. This gene that has been associated with Kawasaki disease. Kawasaki disease is an acute febrile illness that involves the inflammation of blood vessels throughout the body. The majority of cases that have been diagnosed involve chil...
ITPKC ITPKC is one of 3 human genes that encode for an Inositol-trisphosphate 3-kinase. This gene that has been associated with Kawasaki disease.[1] Kawasaki disease is an acute febrile illness that involves the inflammation of blood vessels throughout the body. The majority of cases that have been diagnosed involve ...
https://www.wikidoc.org/index.php/ITPKC
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wikidoc
IUBMB
IUBMB The International Union of Biochemistry and Molecular Biology (IUBMB) is an international non-governmental organisation concerned with biochemistry and molecular biology. Formed in 1955 as the International Union of Biochemistry, the union has presently 77 member countries (as of 2008). IUBMB organizes a triennia...
IUBMB Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] The International Union of Biochemistry and Molecular Biology (IUBMB) is an international non-governmental organisation concerned with biochemistry and molecular biology. Formed in 1955 as the International Union of Biochemistry, the union has presently 77 membe...
https://www.wikidoc.org/index.php/IUBMB
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wikidoc
IUPAP
IUPAP The International Union of Pure and Applied Physics (IUPAP) is an international non-governmental organization devoted to the advancement of physics. It was established in 1922 and the first General Assembly was held in 1923 in Paris. The aims of the Union are: to stimulate and promote international cooperation in...
IUPAP Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] The International Union of Pure and Applied Physics (IUPAP) is an international non-governmental organization devoted to the advancement of physics. It was established in 1922 and the first General Assembly was held in 1923 in Paris. The aims of the Union are: t...
https://www.wikidoc.org/index.php/IUPAP
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wikidoc
Iboga
Iboga Iboga (Tabernanthe iboga), also known as Black bugbane, is a perennial rainforest shrub and hallucinogen, native to western Africa. Iboga stimulates the central nervous system when taken in small doses and induces visions in larger doses. Normally growing to a height of 2 m, T. iboga may eventually grow into a sm...
Iboga Iboga (Tabernanthe iboga), also known as Black bugbane, is a perennial rainforest shrub and hallucinogen, native to western Africa. Iboga stimulates the central nervous system when taken in small doses and induces visions in larger doses. Normally growing to a height of 2 m, T. iboga may eventually grow into a s...
https://www.wikidoc.org/index.php/Iboga
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wikidoc
Ichor
Ichor In Greek mythology, ichor (Greek Template:Polytonic) is the mineral that is the Greek gods' blood, sometimes said to have been present in ambrosia or nectar. When a god was injured and bled, the ichor made his or her blood poisonous to mortals. Ichor has also been used to mean the blood in a vampire's veins. Wh...
Ichor Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] In Greek mythology, ichor (Greek Template:Polytonic) is the mineral[citation needed] that is the Greek gods' blood, sometimes said to have been present in ambrosia or nectar.[citation needed] When a god was injured and bled, the ichor made his or her blood pois...
https://www.wikidoc.org/index.php/Ichor
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wikidoc
Ileum
Ileum # Overview In anatomy of the digestive system, the ileum is the final section of the small intestine. It is about 2-4 m long in humans, follows the duodenum and jejunum, and is separated from the cecum by the ileocecal valve (ICV). The pH in the ileum is usually between 7 and 8 (neutral or slightly alkaline). ...
Ileum Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview Template:Infobox Anatomy In anatomy of the digestive system, the ileum is the final section of the small intestine. It is about 2-4 m long in humans, follows the duodenum and jejunum, and is separated from the cecum by the ileocecal valve (ICV). The...
https://www.wikidoc.org/index.php/Ileum
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wikidoc
Imine
Imine An imine is a functional group or chemical compound containing a carbon-nitrogen double bond . Due to their diverse reactivity, imines are common substrates in a wide variety of transformations. An imine can be synthesised by the nucleophilic addition of an amine to a ketone or aldehyde giving a hemiaminal -C(OH...
Imine An imine is a functional group or chemical compound containing a carbon-nitrogen double bond [1]. Due to their diverse reactivity, imines are common substrates in a wide variety of transformations. An imine can be synthesised by the nucleophilic addition of an amine to a ketone or aldehyde giving a hemiaminal -...
https://www.wikidoc.org/index.php/Imine
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wikidoc
Nerve
Nerve # Overview A nerve is an enclosed, cable-like bundle of axons (the long, slender projection of a neuron). Neurons are sometimes called nerve cells, though this term is technically imprecise since many neurons do not form nerves, and nerves also include the glial cells that ensheath the axons in myelin. # Anatom...
Nerve Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview A nerve is an enclosed, cable-like bundle of axons (the long, slender projection of a neuron). Neurons are sometimes called nerve cells, though this term is technically imprecise since many neurons do not form nerves, and nerves also include the glia...
https://www.wikidoc.org/index.php/Innervate
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wikidoc
Venom
Venom Venom (literally, poison of animal origin) is any of a variety of toxins used by certain types of animals, for the purpose of defense and hunting. Generally, venom is injected while other toxins are absorbed by ingestion or through the skin. The animals most widely known to use venom are snakes, some species of w...
Venom Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Venom (literally, poison of animal origin) is any of a variety of toxins used by certain types of animals, for the purpose of defense and hunting. Generally, venom is injected while other toxins are absorbed by ingestion or through the skin. The animals most wid...
https://www.wikidoc.org/index.php/Insect_venom
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wikidoc
JADE1
JADE1 JADE1 is a protein that in humans is encoded by the JADE1 gene. # Family A small family of proteins named Gene for Apoptosis and Differentiation (JADE) includes three members encoded by individual genes: Plant Homeo-domain-17 (PHF17, JADE1), PHF16 (JADE3), and PHF15 (JADE2). All JADE family proteins bear two not...
JADE1 JADE1 is a protein that in humans is encoded by the JADE1 gene.[1][2][3][4] # Family A small family of proteins named Gene for Apoptosis and Differentiation (JADE)[2] includes three members encoded by individual genes: Plant Homeo-domain-17 (PHF17, JADE1), PHF16 (JADE3), and PHF15 (JADE2). All JADE family prote...
https://www.wikidoc.org/index.php/JADE1
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wikidoc
Joule
Joule The joule (Template:PronEng or Template:IPA) (symbol: J) is the SI unit of energy. It was named after James Prescott Joule for his work on the relationship between heat, electricity and mechanical work. # Description One joule is the work done, or energy expended, by a force of one newton moving one meter along...
Joule The joule (Template:PronEng or Template:IPA) (symbol: J) is the SI unit of energy. It was named after James Prescott Joule for his work on the relationship between heat, electricity and mechanical work. # Description One joule is the work done, or energy expended, by a force of one newton moving one meter alon...
https://www.wikidoc.org/index.php/Joule
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wikidoc
Juice
Juice Juice is a liquid naturally contained in fruit or vegetable tissue. Juice is prepared by mechanically squeezing or macerating fresh fruits or vegetables without the application of heat or solvents. For example, orange juice is the liquid extract of the fruit of the orange tree. Juice may be prepared in the home f...
Juice Juice is a liquid naturally contained in fruit or vegetable tissue. Juice is prepared by mechanically squeezing or macerating fresh fruits or vegetables without the application of heat or solvents. For example, orange juice is the liquid extract of the fruit of the orange tree. Juice may be prepared in the home ...
https://www.wikidoc.org/index.php/Juice
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wikidoc
KCNA2
KCNA2 Potassium voltage-gated channel subfamily A member 2 also known as Kv1.2 is a protein that in humans is encoded by the KCNA2 gene. # Function Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulati...
KCNA2 Potassium voltage-gated channel subfamily A member 2 also known as Kv1.2 is a protein that in humans is encoded by the KCNA2 gene.[1][2] # Function Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include r...
https://www.wikidoc.org/index.php/KCNA2
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wikidoc
KCNA3
KCNA3 Potassium voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene. Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions in...
KCNA3 Potassium voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene.[1][2][3] Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse fu...
https://www.wikidoc.org/index.php/KCNA3
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wikidoc
KCNA4
KCNA4 Potassium voltage-gated channel subfamily A member 4 also known as Kv1.4 is a protein that in humans is encoded by the KCNA4 gene. It contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential. # Description Pot...
KCNA4 Potassium voltage-gated channel subfamily A member 4 also known as Kv1.4 is a protein that in humans is encoded by the KCNA4 gene.[1][2][3] It contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.[4] # De...
https://www.wikidoc.org/index.php/KCNA4
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wikidoc
KCNA5
KCNA5 Potassium voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene. # Function Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. KCNA5 encodes ...
KCNA5 Potassium voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene.[1] # Function Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. KCNA5 enco...
https://www.wikidoc.org/index.php/KCNA5
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wikidoc
KCNB1
KCNB1 Potassium voltage-gated channel, Shab-related subfamily, member 1, also known as KCNB1 or Kv2.1, is a protein that, in humans, is encoded by the KCNB1 gene. Potassium voltage-gated channel subfamily B member one, or simply known as KCNB1, is a delayed rectifier and voltage-gated potassium channel found throughout...
KCNB1 Potassium voltage-gated channel, Shab-related subfamily, member 1, also known as KCNB1 or Kv2.1, is a protein that, in humans, is encoded by the KCNB1 gene.[1][2][3] Potassium voltage-gated channel subfamily B member one, or simply known as KCNB1, is a delayed rectifier and voltage-gated potassium channel found ...
https://www.wikidoc.org/index.php/KCNB1
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wikidoc
KCNC1
KCNC1 Potassium voltage-gated channel subfamily C member 1 is a protein that in humans is encoded by the KCNC1 gene. The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies,...
KCNC1 Potassium voltage-gated channel subfamily C member 1 is a protein that in humans is encoded by the KCNC1 gene.[1][2][3] The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to one of these su...
https://www.wikidoc.org/index.php/KCNC1
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wikidoc
KCNC2
KCNC2 Potassium voltage-gated channel subfamily C member 2 is a protein that in humans is encoded by the KCNC2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit (Kv3.2). # Expression pattern Kv3.1 and Kv3.2 channels are prominently expressed in neurons that fire at high frequency. Kv3...
KCNC2 Potassium voltage-gated channel subfamily C member 2 is a protein that in humans is encoded by the KCNC2 gene.[1][1][2] The protein encoded by this gene is a voltage-gated potassium channel subunit (Kv3.2).[3] # Expression pattern Kv3.1 and Kv3.2 channels are prominently expressed in neurons that fire at high f...
https://www.wikidoc.org/index.php/KCNC2
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wikidoc
KCND3
KCND3 Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential. # Function Voltag...
KCND3 Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene.[1][2][3] It contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.[4] # Fu...
https://www.wikidoc.org/index.php/KCND3
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wikidoc
KCNE1
KCNE1 Potassium voltage-gated channel subfamily E member 1 is a protein that in humans is encoded by the KCNE1 gene. Voltage-gated potassium channels (Kv) represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotrans...
KCNE1 Potassium voltage-gated channel subfamily E member 1 is a protein that in humans is encoded by the KCNE1 gene.[1][2] Voltage-gated potassium channels (Kv) represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neu...
https://www.wikidoc.org/index.php/KCNE1
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wikidoc
KCNE2
KCNE2 Potassium voltage-gated channel subfamily E member 2 (KCNE2), also known as MinK-related peptide 1 (MiRP1), is a protein that in humans is encoded by the KCNE2 gene on chromosome 21. MiRP1 is a voltage-gated potassium channel accessory subunit (beta subunit) associated with Long QT syndrome. It is ubiquitously ex...
KCNE2 Potassium voltage-gated channel subfamily E member 2 (KCNE2), also known as MinK-related peptide 1 (MiRP1), is a protein that in humans is encoded by the KCNE2 gene on chromosome 21.[1][2] MiRP1 is a voltage-gated potassium channel accessory subunit (beta subunit) associated with Long QT syndrome.[1] It is ubiqu...
https://www.wikidoc.org/index.php/KCNE2
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wikidoc
KCNE3
KCNE3 Potassium voltage-gated channel, Isk-related family, member 3 (KCNE3), also known as MinK-related peptide 2 (MiRP2) is a protein that in humans is encoded by the KCNE3 gene. # Function Voltage-gated potassium channels (Kv) represent the most complex class of voltage-gated ion channels from both functional and s...
KCNE3 Potassium voltage-gated channel, Isk-related family, member 3 (KCNE3), also known as MinK-related peptide 2 (MiRP2) is a protein that in humans is encoded by the KCNE3 gene.[1][2] # Function Voltage-gated potassium channels (Kv) represent the most complex class of voltage-gated ion channels from both functiona...
https://www.wikidoc.org/index.php/KCNE3
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wikidoc
KCNE4
KCNE4 Potassium voltage-gated channel subfamily E member 4, originally named MinK-related peptide 3 or MiRP3 when it was discovered, is a protein that in humans is encoded by the KCNE4 gene. # Function Voltage-gated potassium channels (Kv) represent the most complex class of voltage-gated ion channels from both functi...
KCNE4 Potassium voltage-gated channel subfamily E member 4, originally named MinK-related peptide 3 or MiRP3 when it was discovered, is a protein that in humans is encoded by the KCNE4 gene.[1][2] # Function Voltage-gated potassium channels (Kv) represent the most complex class of voltage-gated ion channels from both...
https://www.wikidoc.org/index.php/KCNE4
e2f6d4d5b664567a7192a5e300471dd510acbdb4
wikidoc
KCNE5
KCNE5 KCNE1-like also known as KCNE1L is a protein that in humans is encoded by the KCNE1L gene. # Function Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter r...
KCNE5 KCNE1-like also known as KCNE1L is a protein that in humans is encoded by the KCNE1L gene.[1][2] # Function Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransm...
https://www.wikidoc.org/index.php/KCNE5
cde95bbefd67d12af6c1fb545c2a68c62d739379
wikidoc
KCNH1
KCNH1 Potassium voltage-gated channel subfamily H member 1 is a protein that in humans is encoded by the KCNH1 gene. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotrans...
KCNH1 Potassium voltage-gated channel subfamily H member 1 is a protein that in humans is encoded by the KCNH1 gene.[1][2][3] Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating ...
https://www.wikidoc.org/index.php/KCNH1
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wikidoc
KCNH5
KCNH5 Potassium voltage-gated channel, subfamily H (eag-related), member 5, also known as KCNH5, is a human gene encoding the Kv10.2 protein. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions incl...
KCNH5 Potassium voltage-gated channel, subfamily H (eag-related), member 5, also known as KCNH5, is a human gene encoding the Kv10.2 protein.[1] Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions ...
https://www.wikidoc.org/index.php/KCNH5
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wikidoc
KCNJ5
KCNJ5 G protein-activated inward rectifier potassium channel 4 is a protein that in humans is encoded by the KCNJ5 gene and is a type of G protein-gated ion channel. # Function Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded b...
KCNJ5 G protein-activated inward rectifier potassium channel 4 is a protein that in humans is encoded by the KCNJ5 gene and is a type of G protein-gated ion channel.[1][2] # Function Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein en...
https://www.wikidoc.org/index.php/KCNJ5
47f4b16be7b0c41f5aeb7a2876a34e8a8840ef11
wikidoc
KCNK2
KCNK2 Potassium channel subfamily K member 2 is a protein that in humans is encoded by the KCNK2 gene. This gene encodes K2P2.1, one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium ou...
KCNK2 Potassium channel subfamily K member 2 is a protein that in humans is encoded by the KCNK2 gene.[1][2][3] This gene encodes K2P2.1, one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks po...
https://www.wikidoc.org/index.php/KCNK2
1d7a2febbec00ff6e84cdef0dd096edbfceac6b5
wikidoc
KCNK3
KCNK3 Potassium channel subfamily K member 3 is a protein that in humans is encoded by the KCNK3 gene. This gene encodes K2P3.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. K2P3.1 is an outwardly rectifying channel that is sensitive to changes in extracellu...
KCNK3 Potassium channel subfamily K member 3 is a protein that in humans is encoded by the KCNK3 gene.[1][2][3][4] This gene encodes K2P3.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. K2P3.1 is an outwardly rectifying channel that is sensitive to changes ...
https://www.wikidoc.org/index.php/KCNK3
144ecf09145384ef007d54ecfcf63f4cda3e8ef0
wikidoc
KCNK4
KCNK4 Potassium channel subfamily K member 4 is a protein that in humans is encoded by the KCNK4 gene. # Function Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes the K2P4....
KCNK4 Potassium channel subfamily K member 4 is a protein that in humans is encoded by the KCNK4 gene.[1][2][3] # Function Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes...
https://www.wikidoc.org/index.php/KCNK4
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wikidoc
KCNK9
KCNK9 Potassium channel subfamily K member 9 is a protein that in humans is encoded by the KCNK9 gene. This gene encodes K2P9.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel is highly expressed in the cerebellum. It is inhibited by extracel...
KCNK9 Potassium channel subfamily K member 9 is a protein that in humans is encoded by the KCNK9 gene.[1][2][3] This gene encodes K2P9.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel is highly expressed in the cerebellum. It is inhibited b...
https://www.wikidoc.org/index.php/KCNK9
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wikidoc
KCNN2
KCNN2 Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, also known as KCNN2, is a protein which in humans is encoded by the KCNN2 gene. KCNN2 is an ion channel protein also known as KCa2.2. # Function Action potentials in vertebrate neurons are followed by an afterhyperpolariza...
KCNN2 Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, also known as KCNN2, is a protein which in humans is encoded by the KCNN2 gene.[1] KCNN2 is an ion channel protein also known as KCa2.2.[2] # Function Action potentials in vertebrate neurons are followed by an afterhyperp...
https://www.wikidoc.org/index.php/KCNN2
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wikidoc
KCNN4
KCNN4 Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, also known as KCNN4, is a human gene encoding the KCa3.1 protein. # Function The KCa3.1 protein is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Ac...
KCNN4 Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, also known as KCNN4, is a human gene encoding the KCa3.1 protein.[1] # Function The KCa3.1 protein is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium...
https://www.wikidoc.org/index.php/KCNN4
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wikidoc
KCNQ4
KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 also known as voltage-gated potassium channel subunit Kv7.4 is a protein that in humans is encoded by the KCNQ4 gene. # Function The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal ...
KCNQ4 Potassium voltage-gated channel subfamily KQT member 4 also known as voltage-gated potassium channel subunit Kv7.4 is a protein that in humans is encoded by the KCNQ4 gene.[1][2][3] # Function The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of...
https://www.wikidoc.org/index.php/KCNQ4
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wikidoc
KCNRG
KCNRG Potassium channel regulator, also known as KCNRG, is a protein which in humans is encoded by theKCNRG gene. # Function KCNRG is a soluble protein with characteristics suggesting it forms hetero-tetramers with voltage-gated K+ channels and inhibits their function. # Clinical significance KCNRG has been found to ...
KCNRG Potassium channel regulator, also known as KCNRG, is a protein which in humans is encoded by theKCNRG gene.[1][2] # Function KCNRG is a soluble protein with characteristics suggesting it forms hetero-tetramers with voltage-gated K+ channels and inhibits their function.[1] # Clinical significance KCNRG has been...
https://www.wikidoc.org/index.php/KCNRG
e296d2dfd02025f2b7057b54da316c290cc3c26a
wikidoc
KCTD7
KCTD7 Potassium channel tetramerisation domain containing 7 is a protein in humans that is encoded by the KCTD7 gene. Alternative splicing results in multiple transcript variants. # Description The KCTD7 gene encodes a member of the potassium channel tetramerisation domain-containing protein family. Family members are...
KCTD7 Potassium channel tetramerisation domain containing 7 is a protein in humans that is encoded by the KCTD7 gene.[1] Alternative splicing results in multiple transcript variants. # Description The KCTD7 gene encodes a member of the potassium channel tetramerisation domain-containing protein family. Family members...
https://www.wikidoc.org/index.php/KCTD7
88848c2b8fe4f7cd4c5a6b164fb43f8fe2c12f10
wikidoc
KDM1A
KDM1A Lysine-specific histone demethylase 1A (LSD1) also known as lysine (K)-specific demethylase 1A (KDM1A) is a protein in humans that is encoded by the KDM1A gene. LSD1 is a flavin-dependent monoamine oxidase, which can demethylate mono- and di-methylated lysines, specifically histone 3, lysines 4 and 9 (H3K4 and H3...
KDM1A Lysine-specific histone demethylase 1A (LSD1) also known as lysine (K)-specific demethylase 1A (KDM1A) is a protein in humans that is encoded by the KDM1A gene.[1] LSD1 is a flavin-dependent monoamine oxidase, which can demethylate mono- and di-methylated lysines, specifically histone 3, lysines 4 and 9 (H3K4 an...
https://www.wikidoc.org/index.php/KDM1A
7818237412722bafe1e7bc734cb9b39e37b1b8a4
wikidoc
KDM2A
KDM2A Lysine-specific demethylase 2A (KDM2A) also known as F-box and leucine-rich repeat protein 11 (FBXL11) is an enzyme that in humans is encoded by the KDM2A gene. KDM2A is a member of the superfamily of alpha-ketoglutarate-dependent hydroxylases, which are non-haem iron-containing proteins. # Function This gene en...
KDM2A Lysine-specific demethylase 2A (KDM2A) also known as F-box and leucine-rich repeat protein 11 (FBXL11) is an enzyme that in humans is encoded by the KDM2A gene.[1][2][3] KDM2A is a member of the superfamily of alpha-ketoglutarate-dependent hydroxylases, which are non-haem iron-containing proteins. # Function Th...
https://www.wikidoc.org/index.php/KDM2A
bf2f54642f983bf34b758b876065062f07bc87fb
wikidoc
KDM2B
KDM2B The human KDM2B gene encodes the protein Lysine (K)-specific demethylase 2B. # Tissue and subcellular distribution KDM2B is broadly and highly expressed in embryonic tissues (especially in the developing central nervous system of vertebrates). Expression of KDM2B is also retained in most organs in adults. The pr...
KDM2B The human KDM2B gene encodes the protein Lysine (K)-specific demethylase 2B.[1] # Tissue and subcellular distribution KDM2B is broadly and highly expressed in embryonic tissues (especially in the developing central nervous system of vertebrates). Expression of KDM2B is also retained in most organs in adults.[2]...
https://www.wikidoc.org/index.php/KDM2B
1baaa4dd90781d7c1660977bb21ee814360f986c
wikidoc
KDM4A
KDM4A Lysine-specific demethylase 4A is an enzyme that in humans is encoded by the KDM4A gene. # Function This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein belongs t...
KDM4A Lysine-specific demethylase 4A is an enzyme that in humans is encoded by the KDM4A gene.[1][2][3] # Function This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein...
https://www.wikidoc.org/index.php/KDM4A
b6418ab12d7ab616e24c7a6c8f8cf10779bbd1ec
wikidoc
KDM4C
KDM4C Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene. # Function This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein belongs to the alpha...
KDM4C Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene.[1][2][3] # Function This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein belongs to...
https://www.wikidoc.org/index.php/KDM4C
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wikidoc
KDM5A
KDM5A Lysine-specific demethylase 5A is an enzyme that in humans is encoded by the KDM5A gene. # Function The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. It was formerly known as ...
KDM5A Lysine-specific demethylase 5A is an enzyme that in humans is encoded by the KDM5A gene.[1][2] # Function The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. It was formerly kn...
https://www.wikidoc.org/index.php/KDM5A
f7ffb777d5a77c963a7edabb10dc5273720f8e97
wikidoc
KDM6B
KDM6B Lysine demethylase 6B is a protein that in humans is encoded by the KDM6B gene. # Regulation during differentation KDM6B was found to be expressional increased during cardiac and endothelial differentation of murine embryonic stem cells. # Small molecule inhibition A small molecule inhibition (GSK-J1) has been ...
KDM6B Lysine demethylase 6B is a protein that in humans is encoded by the KDM6B gene. [1] # Regulation during differentation KDM6B was found to be expressional increased during cardiac and endothelial differentation of murine embryonic stem cells.[2] # Small molecule inhibition A small molecule inhibition (GSK-J1) h...
https://www.wikidoc.org/index.php/KDM6B
d145dadb3c46155726134fab02f8474b73d321a2
wikidoc
KEAP1
KEAP1 Kelch-like ECH-associated protein 1 is a protein that in humans is encoded by the Keap1 gene. # Structure Keap1 has four discrete protein domains. The N-terminal Broad complex, Tramtrack and Bric-à-Brac (BTB) domain contains the Cys151 residue, which is one of the important cysteines in stress sensing. The int...
KEAP1 Kelch-like ECH-associated protein 1 is a protein that in humans is encoded by the Keap1 gene.[1] # Structure Keap1 has four discrete protein domains. The N-terminal Broad complex, Tramtrack and Bric-à-Brac (BTB) domain contains the Cys151 residue, which is one of the important cysteines in stress sensing. The...
https://www.wikidoc.org/index.php/KEAP1
631eb29f9445e260202d5f7dbc9f8dfa32b25776
wikidoc
KIF15
KIF15 Kinesin family member 15 is a protein that in humans is encoded by the KIF15 gene. This gene encodes a motor protein that is part of the kinesin superfamily. KIF15 maintains half spindle separation by opposing forces generated by other motor proteins. KIF15 co-localizes with microtubules and actin filaments in b...
KIF15 Kinesin family member 15 is a protein that in humans is encoded by the KIF15 gene.[1] This gene encodes a motor protein that is part of the kinesin superfamily. KIF15 maintains half spindle separation by opposing forces generated by other motor proteins. KIF15 co-localizes with microtubules and actin filaments ...
https://www.wikidoc.org/index.php/KIF15
950fef32286a50315abb12de02d170c346b7011b
wikidoc
KIF1A
KIF1A Kinesin-like protein KIF1A, also known as axonal transporter of synaptic vesicles or microtubule-based motor KIF1A, is a protein that in humans is encoded by the KIF1A gene. # Function KIF1A is a member of the kinesin family. This protein is highly similar to mouse heavy-chain kinesin member 1A protein, which is...
KIF1A Kinesin-like protein KIF1A, also known as axonal transporter of synaptic vesicles or microtubule-based motor KIF1A, is a protein that in humans is encoded by the KIF1A gene.[1][2][3] # Function KIF1A is a member of the kinesin family. This protein is highly similar to mouse heavy-chain kinesin member 1A protein...
https://www.wikidoc.org/index.php/KIF1A
1adacda68030a021ab03836a1ba5e076e2219879
wikidoc
KIF22
KIF22 Kinesin-like protein KIF22 is a protein that in humans is encoded by the KIF22 gene. The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The...
KIF22 Kinesin-like protein KIF22 is a protein that in humans is encoded by the KIF22 gene.[1][2][3] The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell div...
https://www.wikidoc.org/index.php/KIF22
833212c8b00340adc8acca22c87acdbced53419c
wikidoc
KIF23
KIF23 Kinesin-like protein KIF23 is a protein that in humans is encoded by the KIF23 gene. # Function ## In cell division KIF23 (also known as Kinesin-6, CHO1/MKLP1, C. elegans ZEN-4 and Drosophila Pavarotti) is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that ...
KIF23 Kinesin-like protein KIF23 is a protein that in humans is encoded by the KIF23 gene.[1][2] # Function ## In cell division KIF23 (also known as Kinesin-6, CHO1/MKLP1, C. elegans ZEN-4 and Drosophila Pavarotti) is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motor...
https://www.wikidoc.org/index.php/KIF23
1c8521b5a741522ddeedab854c6db377ef46b35d
wikidoc
KIF3B
KIF3B Kinesin-like protein KIF3B is a protein that in humans is encoded by the KIF3B gene. # Function The protein encoded by this gene forms a heterotrimeric motor complex with kinesin family member 3A and KAP3 (kinesin accessory protein 3) to drive intra-flagellar transport and possibly to aid in chromosome movement ...
KIF3B Kinesin-like protein KIF3B is a protein that in humans is encoded by the KIF3B gene.[1][2] # Function The protein encoded by this gene forms a heterotrimeric motor complex with kinesin family member 3A and KAP3 (kinesin accessory protein 3) to drive intra-flagellar transport and possibly to aid in chromosome mo...
https://www.wikidoc.org/index.php/KIF3B
18be37f5c2696be682d5fbc9373d47e900de085e
wikidoc
KLF13
KLF13 Kruppel-like factor 13, also known as KLF13, is a protein that in humans is encoded by the KLF13 gene. There is some evidence for KLF13 having a role in obesity. A methylation site, cg07814318, within the first intron of KLF13 has been associated with obesity and orexigenic processes. Ghrelin levels also positi...
KLF13 Kruppel-like factor 13, also known as KLF13, is a protein that in humans is encoded by the KLF13 gene.[1][2][3] There is some evidence for KLF13 having a role in obesity. A methylation site, cg07814318, within the first intron of KLF13 has been associated with obesity and orexigenic processes.[4] Ghrelin level...
https://www.wikidoc.org/index.php/KLF13
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wikidoc
KLF14
KLF14 Krüppel-like factor 14, also known as basic transcription element-binding protein 5 (BTEB5) is a protein that in humans is encoded by the KLF14 gene. The corresponding Klf14 mouse gene is known as Sp6. # Function KLF14 is a member of the Krüppel-like factor family of transcription factors. It regulates the tran...
KLF14 Krüppel-like factor 14, also known as basic transcription element-binding protein 5 (BTEB5) is a protein that in humans is encoded by the KLF14 gene.[1] The corresponding Klf14 mouse gene is known as Sp6.[2] # Function KLF14 is a member of the Krüppel-like factor family of transcription factors. It regulates t...
https://www.wikidoc.org/index.php/KLF14
b52418768a7b8bb835007ada6c6ce965610471f9
wikidoc
KLF15
KLF15 Krüppel-like factor 15 is a protein that in humans is encoded by the KLF15 gene in the Krüppel-like factor family. Its former designation KKLF stands for kidney-enriched Krüppel-like factor. # Expression Activated glucocorticoid receptor upregulates the expression of KLF15. KLF15 is increased by fasting and dec...
KLF15 Krüppel-like factor 15 is a protein that in humans is encoded by the KLF15 gene[1] in the Krüppel-like factor family. Its former designation KKLF stands for kidney-enriched Krüppel-like factor.[2] # Expression Activated glucocorticoid receptor upregulates the expression of KLF15.[3] KLF15 is increased by fasti...
https://www.wikidoc.org/index.php/KLF15
1ff98c2eee79f44ac91bc4d4bf75fc16aeef55b5
wikidoc
KLRC2
KLRC2 NKG2-C type II integral membrane protein is a protein that in humans is encoded by the KLRC2 gene. # Function Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated imm...
KLRC2 NKG2-C type II integral membrane protein is a protein that in humans is encoded by the KLRC2 gene.[1][2] # Function Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-media...
https://www.wikidoc.org/index.php/KLRC2
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wikidoc
KLRD1
KLRD1 CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D, member 1 (KLRD1) is a human gene. The protein encoded by CD94 gene is a lectin, cluster of differentiation and a receptor that is involved in cell signaling and is expressed on the surface of natural killer cells in ...
KLRD1 CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D, member 1 (KLRD1) is a human gene.[1] The protein encoded by CD94 gene is a lectin, cluster of differentiation and a receptor that is involved in cell signaling and is expressed on the surface of natural killer cells...
https://www.wikidoc.org/index.php/KLRD1
fd3b789bcba55bd77215b60f99aa4350217d9167
wikidoc
KLRG1
KLRG1 Killer cell lectin-like receptor subfamily G member 1 is a protein that in humans is encoded by the KLRG1 gene. # Function Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell...
KLRG1 Killer cell lectin-like receptor subfamily G member 1 is a protein that in humans is encoded by the KLRG1 gene.[1][2][3][4][5] # Function Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific ...
https://www.wikidoc.org/index.php/KLRG1
bbf55635acef1bbc3cd65924b59dde2aec038094
wikidoc
KMT2D
KMT2D Histone-lysine N-methyltransferase 2D (KMT2D), also known as MLL4 and sometimes MLL2 in humans and Mll4 in mice, is a major mammalian histone H3 lysine 4 (H3K4) mono-methyltransferase. It is part of a family of six Set1-like H3K4 methyltransferases that also contains KMT2A (or MLL1), KMT2B (or MLL2), KMT2C (or ML...
KMT2D Histone-lysine N-methyltransferase 2D (KMT2D), also known as MLL4 and sometimes MLL2 in humans and Mll4 in mice, is a major mammalian histone H3 lysine 4 (H3K4) mono-methyltransferase.[1] It is part of a family of six Set1-like H3K4 methyltransferases that also contains KMT2A (or MLL1), KMT2B (or MLL2), KMT2C (o...
https://www.wikidoc.org/index.php/KMT2D
b594dff280f8bc4d8c078f581cacb0217102c5dc
wikidoc
KRT31
KRT31 Keratin, type I cuticular Ha1 is a protein that in humans is encoded by the KRT31 gene. # Function The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratin...
KRT31 Keratin, type I cuticular Ha1 is a protein that in humans is encoded by the KRT31 gene.[1][2][3] # Function The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I ha...
https://www.wikidoc.org/index.php/KRT31
e09d3aa7c3cb0d7de090dd8caf8623500c23860a
wikidoc
KRT71
KRT71 KRT71 is a keratin gene. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are cluste...
KRT71 KRT71 is a keratin gene. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clust...
https://www.wikidoc.org/index.php/KRT71
63c90ee03ccdc0f582dfda8a77ba4b21137f501b
wikidoc
Kampo
Kampo Kampō (or Kanpō, 漢方) medicine is the Japanese study and adaptation of Traditional Chinese medicine. The basic works of Chinese medicine came to Japan between the 7th and 9th centuries. Since then, the Japanese have created their own unique herbal medical system and diagnosis. Kampo uses most of the Chinese medi...
Kampo Kampō (or Kanpō, 漢方) medicine is the Japanese study and adaptation of Traditional Chinese medicine. The basic works of Chinese medicine came to Japan between the 7th and 9th centuries. [1] Since then, the Japanese have created their own unique herbal medical system and diagnosis. Kampo uses most of the Chinese ...
https://www.wikidoc.org/index.php/Kampo
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wikidoc
Katal
Katal The katal (symbol: kat) is the SI unit of catalytic activity. It is a derived SI unit for expressing quantity values of catalytic activity of enzymes and other catalysts. Its use is recommended by the General Conference on Weights and Measures and other international organizations. It replaces the non-SI enzyme u...
Katal The katal (symbol: kat) is the SI unit of catalytic activity.[1] It is a derived SI unit for expressing quantity values of catalytic activity of enzymes and other catalysts. Its use is recommended by the General Conference on Weights and Measures and other international organizations. It replaces the non-SI enzy...
https://www.wikidoc.org/index.php/Katal
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wikidoc
Kudzu
Kudzu # Description Kudzu is a climbing, woody or semi-woody, perennial vine capable of reaching heights of 20–30 m (66-98 ft) in trees, but also scrambles extensively over lower vegetation. The leaves are deciduous, alternate and compound, with a petiole (leaf stem) 10–20 cm (4–8 in) long and three broad leaflets 14–...
Kudzu Template:Nihongo, Pueraria lobata (syn. P. montana, P. thunbergiana), is one of about 20 species in the genus Pueraria in the pea family Fabaceae, subfamily Faboideae. It is native to southern Japan and southeast China in eastern Asia. The name comes from the Japanese word for this plant, kuzu. The other species...
https://www.wikidoc.org/index.php/Kudzu
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Kumis
Kumis Kumis is a fermented dairy product traditionally made from mares' milk. The drink remains important to the people of the Central Asian steppes, including the Bashkirs, Kazakhs, Kyrgyz, Mongols and Yakuts. Kumis is a dairy product similar to kefir, but is produced from a liquid starter culture, in contrast to the ...
Kumis Kumis is a fermented dairy product traditionally made from mares' milk. The drink remains important to the people of the Central Asian steppes, including the Bashkirs, Kazakhs, Kyrgyz, Mongols and Yakuts.[1] Kumis is a dairy product similar to kefir, but is produced from a liquid starter culture, in contrast to ...
https://www.wikidoc.org/index.php/Kumis
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wikidoc
Kv1.1
Kv1.1 Potassium voltage-gated channel subfamily A member 1 also known as Kv1.1 is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene. The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel. # Genomics The gene is located on the Watson (plus) s...
Kv1.1 Potassium voltage-gated channel subfamily A member 1 also known as Kv1.1 is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene.[1][2][3] The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel.[4] # Genomics The gene is located on the Wa...
https://www.wikidoc.org/index.php/Kv1.1
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wikidoc
Kvass
Kvass Kvass (literally "leaven"; borrowed in the 16th century from Russian квас), sometimes translated into English as bread drink, is a fermented mildly alcoholic beverage made from black or rye bread. It is popular in Russia, Belarus, Ukraine and other Eastern and Central European countries as well as in all ex-Sovie...
Kvass Kvass (literally "leaven"; borrowed in the 16th century from Russian квас[1]), sometimes translated into English as bread drink, is a fermented mildly alcoholic beverage made from black or rye bread. It is popular in Russia, Belarus, Ukraine and other Eastern and Central European countries as well as in all ex-S...
https://www.wikidoc.org/index.php/Kvass
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wikidoc
LACTB
LACTB Serine beta-lactamase-like protein LACTB, mitochondrial is an enzyme that in humans is encoded by the LACTB gene. This gene encodes a 54 kDa protein sharing significant sequence similarity to serine proteases of the penicillin binding protein and beta-lactamase superfamily occurring in bacteria. It is involved ...
LACTB Serine beta-lactamase-like protein LACTB, mitochondrial is an enzyme that in humans is encoded by the LACTB gene.[1][2] This gene encodes a 54 kDa protein sharing significant sequence similarity to serine proteases of the penicillin binding protein and beta-lactamase superfamily occurring in bacteria. [3] It is...
https://www.wikidoc.org/index.php/LACTB
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wikidoc
LAMP1
LAMP1 Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34). Lysos...
LAMP1 Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34). Lyso...
https://www.wikidoc.org/index.php/LAMP1
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wikidoc
LAMP3
LAMP3 Lysosome-associated membrane glycoprotein 3 (LAMP3, Lamp3) is a protein that in humans is encoded by the LAMP3 gene. It is one of the lysosome-associated membrane glycoproteins. LAMP3 also known as DC-LAMP (Dendritic cell lysosomal associated membrane glycoprotein) is a member of the LAMP family along with LAMP1 ...
LAMP3 Lysosome-associated membrane glycoprotein 3 (LAMP3, Lamp3) is a protein that in humans is encoded by the LAMP3 gene.[1][2] It is one of the lysosome-associated membrane glycoproteins. LAMP3 also known as DC-LAMP (Dendritic cell lysosomal associated membrane glycoprotein) is a member of the LAMP family along with...
https://www.wikidoc.org/index.php/LAMP3
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wikidoc
LARGE
LARGE Glycosyltransferase-like protein LARGE1 is an enzyme that in humans is encoded by the LARGE gene. # Function This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. The exact function of LARGE, a golgi protein, remains uncertain. It encodes...
LARGE Glycosyltransferase-like protein LARGE1 is an enzyme that in humans is encoded by the LARGE gene.[1][2][3][4] # Function This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. The exact function of LARGE, a golgi protein, remains uncertai...
https://www.wikidoc.org/index.php/LARGE
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wikidoc
LARP1
LARP1 La-related protein 1 (LARP1) is a 150 kDa protein that in humans is encoded by the LARP1 gene. LARP1 is a novel target of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway, a circuitry often hyperactivated in cancer which regulates cell growth and proliferation primarily through the regulatio...
LARP1 La-related protein 1 (LARP1) is a 150 kDa protein that in humans is encoded by the LARP1 gene.[1][2][1][3][2] LARP1 is a novel target of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway, a circuitry often hyperactivated in cancer which regulates cell growth and proliferation primarily throu...
https://www.wikidoc.org/index.php/LARP1
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wikidoc
LASIK
LASIK # Overview LASIK or Lasik (laser-assisted in situ keratomileusis) is a type of refractive laser eye surgery performed by ophthalmologists for correcting myopia, hyperopia, and astigmatism. The procedure is generally preferred to photorefractive keratectomy, PRK, (also called ASA, Advanced Surface Ablation) becau...
LASIK # Overview LASIK or Lasik (laser-assisted in situ keratomileusis) is a type of refractive laser eye surgery performed by ophthalmologists for correcting myopia, hyperopia, and astigmatism.[1] The procedure is generally preferred to photorefractive keratectomy, PRK, (also called ASA, Advanced Surface Ablation) be...
https://www.wikidoc.org/index.php/LASIK
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wikidoc
LECT2
LECT2 Leukocyte cell-derived chemotaxin-2 (LECT2) is a protein first described in 1996 as a chemotactic factor for neutrophils, i.e. it stimulated human neutrophils to move directionally in an in vitro assay system. The protein was detected in and purified from cultures of Phytohaemagglutinin-activated human T-cell leu...
LECT2 Leukocyte cell-derived chemotaxin-2 (LECT2) is a protein first described in 1996 as a chemotactic factor for neutrophils, i.e. it stimulated human neutrophils to move directionally in an in vitro assay system. The protein was detected in and purified from cultures of Phytohaemagglutinin-activated human T-cell le...
https://www.wikidoc.org/index.php/LECT2
e2960ed4966b09da42168a2d0c0e093e80bc96a6
wikidoc
LEKTI
LEKTI Lympho-epithelial Kazal-type-related inhibitor (LEKTI) also known as serine protease inhibitor Kazal-type 5 (SPINK5) is a protein that in humans is encoded by the SPINK5 gene. # Structure and function LEKTI is a large multidomain serine protease inhibitor expressed in stratified epithelial tissue. It consists of...
LEKTI Lympho-epithelial Kazal-type-related inhibitor (LEKTI) also known as serine protease inhibitor Kazal-type 5 (SPINK5) is a protein that in humans is encoded by the SPINK5 gene.[1][2] # Structure and function LEKTI is a large multidomain serine protease inhibitor expressed in stratified epithelial tissue. It cons...
https://www.wikidoc.org/index.php/LEKTI
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wikidoc
LENG9
LENG9 Leukocyte Receptor Cluster Member 9 (LENG 9) is an uncharacterized protein encoded by the LENG9 gene. In humans, LENG9 is predicted to play a role in fertility and reproductive disorders associated with female endometrium structures. # Gene ## Location LENG9 is located at 19q13.42 on chromosome 19, spanning th...
LENG9 Leukocyte Receptor Cluster Member 9 (LENG 9) is an uncharacterized protein encoded by the LENG9 gene.[1][2] In humans, LENG9 is predicted to play a role in fertility and reproductive disorders associated with female endometrium structures.[3][4] # Gene ## Location LENG9 is located at 19q13.42 on chromosome 19...
https://www.wikidoc.org/index.php/LENG9
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wikidoc
LETM1
LETM1 Leucine zipper-EF-hand containing transmembrane protein 1 is a protein that in humans is encoded by the LETM1 gene. # Structure The LETM1 protein has a transmembrane domain and a casein kinase 2 and protein kinase C phosphorylation site. The LETM1 gene is expressed in the mitochondria of many eukaryotes indicat...
LETM1 Leucine zipper-EF-hand containing transmembrane protein 1 is a protein that in humans is encoded by the LETM1 gene.[1] # Structure The LETM1 protein has a transmembrane domain and a casein kinase 2 and protein kinase C phosphorylation site.[2] The LETM1 gene is expressed in the mitochondria of many eukaryotes ...
https://www.wikidoc.org/index.php/LETM1
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wikidoc
LIMK1
LIMK1 LIM domain kinase 1 is an enzyme that in humans is encoded by the LIMK1 gene. # Function There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function...
LIMK1 LIM domain kinase 1 is an enzyme that in humans is encoded by the LIMK1 gene.[1][2] # Function There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually f...
https://www.wikidoc.org/index.php/LIMK1
359243b6fdb5a1d7fa012d58f7cdacc7ebaf7500
wikidoc
LIMS1
LIMS1 LIM and senescent cell antigen-like-containing domain protein 1 is a protein that in humans is encoded by the LIMS1 gene. # Function The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM...
LIMS1 LIM and senescent cell antigen-like-containing domain protein 1 is a protein that in humans is encoded by the LIMS1 gene.[1][2][3] # Function The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling throu...
https://www.wikidoc.org/index.php/LIMS1
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wikidoc
LIN28
LIN28 Lin-28 homolog A is a protein that in humans is encoded by the LIN28 gene. LIN28 encodes an RNA-binding protein that binds to and enhances the translation of the IGF-2 (insulin-like growth factor 2) mRNA. Lin28 binds to the let-7 pre-microRNA and blocks production of the mature let-7 microRNA in mouse embryonic s...
LIN28 Lin-28 homolog A is a protein that in humans is encoded by the LIN28 gene.[1][2] LIN28 encodes an RNA-binding protein[3] that binds to and enhances the translation of the IGF-2 (insulin-like growth factor 2) mRNA.[4] Lin28 binds to the let-7 pre-microRNA and blocks production of the mature let-7 microRNA in mous...
https://www.wikidoc.org/index.php/LIN28
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wikidoc
LMAN1
LMAN1 Protein ERGIC-53 also known as ER-Golgi intermediate compartment 53 kDa protein or lectin mannose-binding 1 is a protein that in humans is encoded by the LMAN1 gene. # Function ERGIC-53 (also named LMAN1) is a type I integral membrane protein localized in the intermediate region (ERGIC) between the endoplasmic r...
LMAN1 Protein ERGIC-53 also known as ER-Golgi intermediate compartment 53 kDa protein or lectin mannose-binding 1 is a protein that in humans is encoded by the LMAN1 gene.[1][2][3] # Function ERGIC-53 (also named LMAN1) is a type I integral membrane protein localized in the intermediate region (ERGIC) between the end...
https://www.wikidoc.org/index.php/LMAN1
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wikidoc
LMTK2
LMTK2 Serine/threonine-protein kinase LMTK2 also known as Lemur tyrosine kinase 2 (LMTK2) is an enzyme that in humans is encoded by the LMTK2 gene. # Function The LMTK2 enzyme belongs to both the protein kinase and the tyrosine kinase families. It contains N-terminus transmembrane helices and a long C-terminal cytopla...
LMTK2 Serine/threonine-protein kinase LMTK2 also known as Lemur tyrosine kinase 2 (LMTK2) is an enzyme that in humans is encoded by the LMTK2 gene.[1][2] # Function The LMTK2 enzyme belongs to both the protein kinase and the tyrosine kinase families. It contains N-terminus transmembrane helices and a long C-terminal ...
https://www.wikidoc.org/index.php/LMTK2
f4e56acffbf64358c9379e5127f599b0e2388c04
wikidoc
LMX1B
LMX1B LIM homeobox transcription factor 1-beta, also known as LMX1B, is a protein which in humans is encoded by the LMX1B gene. # Function LMX1B is a LIM homeobox transcription factor which plays a central role in dorso-ventral patterning of the vertebrate limb. # Clinical significance Mutations in the LMX1B gene are...
LMX1B LIM homeobox transcription factor 1-beta, also known as LMX1B, is a protein which in humans is encoded by the LMX1B gene.[1][2] # Function LMX1B is a LIM homeobox transcription factor which plays a central role in dorso-ventral patterning of the vertebrate limb.[3] # Clinical significance Mutations in the LMX1...
https://www.wikidoc.org/index.php/LMX1B
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wikidoc
LONP1
LONP1 Lon protease homolog, mitochondrial is an enzyme that in humans is encoded by the LONP1 gene. # Structure This gene encoded a mitochondrial matrix protein that is the subunit of a barrel-shaped homo-oligometric protein complex, the Lon protease. Lon protease is a member of ATP-dependent proteases (AAA+ protease...
LONP1 Lon protease homolog, mitochondrial is an enzyme that in humans is encoded by the LONP1 gene.[1][2][3][4] # Structure This gene encoded a mitochondrial matrix protein that is the subunit of a barrel-shaped homo-oligometric protein complex, the Lon protease. Lon protease is a member of ATP-dependent proteases (...
https://www.wikidoc.org/index.php/LONP1
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wikidoc
LOXL1
LOXL1 Lysyl oxidase homolog 1, also known as LOXL1, is an enzyme which in humans is encoded by the LOXL1 gene. # Function This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amin...
LOXL1 Lysyl oxidase homolog 1, also known as LOXL1, is an enzyme which in humans is encoded by the LOXL1 gene.[1][2] # Function This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-depende...
https://www.wikidoc.org/index.php/LOXL1
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wikidoc
LOXL2
LOXL2 Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the LOXL2 gene. # Function This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyse...
LOXL2 Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the LOXL2 gene.[1][2] # Function This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that c...
https://www.wikidoc.org/index.php/LOXL2