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wikidoc
LOXL3
LOXL3 Lysyl oxidase homolog 3 is an enzyme that in humans is encoded by the LOXL3 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first ...
LOXL3 Lysyl oxidase homolog 3 is an enzyme that in humans is encoded by the LOXL3 gene.[1][2] This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the...
https://www.wikidoc.org/index.php/LOXL3
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LPAR6
LPAR6 Lysophosphatidic acid receptor 6 also known as LPA6, P2RY5, and GPR87, is a protein that in humans is encoded by the LPAR6 gene. LPA6 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA). The protein encoded by this gene belongs to the family of G-protein coupled rec...
LPAR6 Lysophosphatidic acid receptor 6 also known as LPA6, P2RY5, and GPR87, is a protein that in humans is encoded by the LPAR6 gene.[1][2][3][4] LPA6 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).[5][6] The protein encoded by this gene belongs to the family of G-...
https://www.wikidoc.org/index.php/LPAR6
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wikidoc
LPIN1
LPIN1 Lipin-1 is a protein that in humans is encoded by the LPIN1 gene. # Function Lipin-1 has phosphatidate phosphatase activity. The nuclear localization of Lipin 1 is regulated by the mammalian Target Of Rapamycin protein kinase and links mTORC1 activity to the regulation of Sterol regulatory element-binding protei...
LPIN1 Lipin-1 is a protein that in humans is encoded by the LPIN1 gene.[1][2][3][4] # Function Lipin-1 has phosphatidate phosphatase activity.[5][6][7] The nuclear localization of Lipin 1 is regulated by the mammalian Target Of Rapamycin protein kinase and links mTORC1 activity to the regulation of Sterol regulatory ...
https://www.wikidoc.org/index.php/LPIN1
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wikidoc
LQT10
LQT10 # Overview Only one mutation in one patient of this Long QT syndrome subtype has been found. # LQT10 This novel susceptibility gene for LQT is SCN4B encoding the protein NaVβ4, an auxiliary subunit to the pore-forming NaV1.5 (gene: SCN5A) subunit of the voltage-gated sodium channel of the heart. The mutation ...
LQT10 Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] # Overview Only one mutation in one patient of this Long QT syndrome subtype has been found. # LQT10 This novel susceptibility gene for LQT is SCN4B encoding the protein NaVβ4, an auxiliary subunit to the pore-forming NaV1.5 (gene: SCN5A) subunit of the volta...
https://www.wikidoc.org/index.php/LQT10
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LRIG1
LRIG1 Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene. It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family , MET and RET. # Model organisms Model organisms have been used in the stud...
LRIG1 Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene.[1][2][3] It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family[4] , MET[5] and RET.[6] # Model organisms Model organisms have be...
https://www.wikidoc.org/index.php/LRIG1
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LRRC7
LRRC7 Leucine rich repeat containing 7 also known as LRRC7, Densin-180, or LAP1 is a protein which in humans is encoded by the LRRC7 gene. # Structure Found to be densely associated to the postsynaptic density (PSD), it has been characterised as a 188 kDa (originally thought to be 180 kDa, hence nomenclature), 1495 r...
LRRC7 Leucine rich repeat containing 7 also known as LRRC7, Densin-180, or LAP1 is a protein which in humans is encoded by the LRRC7 gene.[1] # Structure Found to be densely associated to the postsynaptic density (PSD), it has been characterised as a 188 kDa (originally thought to be 180 kDa, hence nomenclature), 14...
https://www.wikidoc.org/index.php/LRRC7
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LRRN3
LRRN3 Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a protein that in humans is encoded by the LRRN3 gene. # Gene The LRRN3 is located on human chromosome 7, at 7q31.1. It contains 6 distinct gt-ag introns, and transcription produces five different mRNAs that...
LRRN3 Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a protein that in humans is encoded by the LRRN3 gene.[1][2] # Gene The LRRN3 is located on human chromosome 7, at 7q31.1.[3] It contains 6 distinct gt-ag introns, and transcription produces five different ...
https://www.wikidoc.org/index.php/LRRN3
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wikidoc
LYNX1
LYNX1 Ly6/neurotoxin 1 is a protein in humans that is encoded by the LYNX1 gene. Alternatively spliced variants encoding different isoforms have been identified. # Function This gene encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphospha...
LYNX1 Ly6/neurotoxin 1 is a protein in humans that is encoded by the LYNX1 gene.[1] Alternatively spliced variants encoding different isoforms have been identified. # Function This gene encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylpho...
https://www.wikidoc.org/index.php/LYNX1
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LYRM7
LYRM7 LYR motif containing 7, also known as Complex III assembly factor LYRM7 or LYR motif-containing protein 7 is a protein that in humans is encoded by the LYRM7 gene. The protein encoded by this gene is a nuclear-encoded mitochondrial matrix protein that stabilizes UQCRFS1 and chaperones it to the CIII complex. Defe...
LYRM7 LYR motif containing 7, also known as Complex III assembly factor LYRM7 or LYR motif-containing protein 7 is a protein that in humans is encoded by the LYRM7 gene.[1] The protein encoded by this gene is a nuclear-encoded mitochondrial matrix protein that stabilizes UQCRFS1 and chaperones it to the CIII complex. ...
https://www.wikidoc.org/index.php/LYRM7
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wikidoc
LZTR1
LZTR1 Leucine-zipper-like transcriptional regulator 1 is a protein that in humans is encoded by the LZTR1 gene. This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded prot...
LZTR1 Leucine-zipper-like transcriptional regulator 1 is a protein that in humans is encoded by the LZTR1 gene.[1][2][3] This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the en...
https://www.wikidoc.org/index.php/LZTR1
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Laser
Laser # Overview A laser is an electronic-optical device that produces coherent radiation. The term "laser" is an acronym for "Light Amplification by Stimulated Emission of Radiation". A typical laser emits light in a narrow, low-divergence beam and with a well-defined wavelength (i.e., monochromatic, corresponding to...
Laser # Overview A laser is an electronic-optical device that produces coherent radiation. The term "laser" is an acronym for "Light Amplification by Stimulated Emission of Radiation".[1][2] A typical laser emits light in a narrow, low-divergence beam and with a well-defined wavelength (i.e., monochromatic, correspond...
https://www.wikidoc.org/index.php/Laser
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Latin
Latin Latin (Latīna, pronounced Template:IPA) is an ancient Indo-European language that was spoken in the Roman Republic and the Roman Empire. The conquests of Rome spread the language all around the Mediterranean and a large part of Europe. It existed in two forms: Classical Latin, used in poetry and formal prose, and...
Latin Template:Infobox Language Latin (Latīna, pronounced Template:IPA) is an ancient Indo-European language that was spoken in the Roman Republic and the Roman Empire. The conquests of Rome spread the language all around the Mediterranean and a large part of Europe. It existed in two forms: Classical Latin, used in p...
https://www.wikidoc.org/index.php/Latin
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Lexan
Lexan LEXAN is a registered trademark for General Electric's brand of highly durable polycarbonate resin thermoplastic intended to replace glass where the need for strength justifies its higher cost. It is a polycarbonate polymer produced by reacting Bisphenol A with carbonyl chloride, also known as phosgene. Lexan is ...
Lexan LEXAN is a registered trademark for General Electric's brand of highly durable polycarbonate resin thermoplastic intended to replace glass where the need for strength justifies its higher cost. It is a polycarbonate polymer produced by reacting Bisphenol A with carbonyl chloride, also known as phosgene. Lexan is...
https://www.wikidoc.org/index.php/Lexan
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Light
Light Light, or visible light, is electromagnetic radiation of a wavelength that is visible to the human eye (about 400–700 nm). In a scientific context, the word light is sometimes used to refer to the entire electromagnetic spectrum. Light is composed of elementary particles called photons. Three primary properties ...
Light Template:Other Light, or visible light, is electromagnetic radiation of a wavelength that is visible to the human eye (about 400–700 nm). In a scientific context, the word light is sometimes used to refer to the entire electromagnetic spectrum.[1] Light is composed of elementary particles called photons. Three ...
https://www.wikidoc.org/index.php/Light
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Lists
Lists # Overview You can create two types of lists: - Bullet Lists: which are unordered and not numbered and have a blue square before the text, or - Numbered Lists: which order or number each item # How to Make a Bullet List: To create a bulletted list, start the line with a star sign "*". Typing this: Yields this: ...
Lists Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] # Overview You can create two types of lists: - Bullet Lists: which are unordered and not numbered and have a blue square before the text, or - Numbered Lists: which order or number each item # How to Make a Bullet List: To create a bulletted list, start the l...
https://www.wikidoc.org/index.php/Lists
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Login
Login # Log In to WikiDoc to Get Credit for Your Contributions! - In the upper right corner there is a link to log in - Enter the required information including your full name (your full name is preferred so that you can be appropriately credited) - Select ‘create new account’ - Your account has been created! - You wi...
Login # Log In to WikiDoc to Get Credit for Your Contributions! - In the upper right corner there is a link to log in - Enter the required information including your full name (your full name is preferred so that you can be appropriately credited) - Select ‘create new account’ - Your account has been created! - You wi...
https://www.wikidoc.org/index.php/Log_in
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wikidoc
Loupe
Loupe A loupe (pronounced loop), is a type of magnification device used to see things one is looking at more closely. In this respect, they are simply a form of a modified microscope, allowing the user to be able to better apply the phenomenon of microscopy to his or her trade. # Commercial uses of loupes Loupes are ...
Loupe A loupe (pronounced loop), is a type of magnification device used to see things one is looking at more closely. In this respect, they are simply a form of a modified microscope, allowing the user to be able to better apply the phenomenon of microscopy to his or her trade. # Commercial uses of loupes Loupes are...
https://www.wikidoc.org/index.php/Loupe
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wikidoc
Lupin
Lupin Lupin, often spelled lupine in North America, is the common name for members of the genus Lupinus in the legume family (Fabaceae). The genus comprises between 200-600 species, with major centers of diversity in South America and western North America - subgen.Platycarpos) and subgen. Lupinus - in the Mediterrane...
Lupin Lupin, often spelled lupine in North America, is the common name for members of the genus Lupinus in the legume family (Fabaceae). The genus comprises between 200-600 species, with major centers of diversity in South America and western North America - subgen.Platycarpos) and subgen. Lupinus - in the Mediterran...
https://www.wikidoc.org/index.php/Lupin
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wikidoc
MACF1
MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 is a protein that in humans is encoded by the MACF1 gene. MACF1 encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. MACF1 is a member of a family of proteins that form bridges between different cytoskeletal elements...
MACF1 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 is a protein that in humans is encoded by the MACF1 gene.[1][2] MACF1 encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. MACF1 is a member of a family of proteins that form bridges between different cytoskeletal e...
https://www.wikidoc.org/index.php/MACF1
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MAGI2
MAGI2 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 also known as membrane-associated guanylate kinase inverted 2 (MAGI-2) and atrophin-1-interacting protein 1 (AIP-1) is an enzyme that in humans is encoded by the MAGI2 gene. # Function The protein encoded by this gene interacts with atr...
MAGI2 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 also known as membrane-associated guanylate kinase inverted 2 (MAGI-2) and atrophin-1-interacting protein 1 (AIP-1) is an enzyme that in humans is encoded by the MAGI2 gene.[1][2][3] # Function The protein encoded by this gene interact...
https://www.wikidoc.org/index.php/MAGI2
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MAGOH
MAGOH Protein mago nashi homolog is a protein that in humans is encoded by the MAGOH gene. Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression...
MAGOH Protein mago nashi homolog is a protein that in humans is encoded by the MAGOH gene.[1][2] Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA exp...
https://www.wikidoc.org/index.php/MAGOH
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wikidoc
MALT1
MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 is a protein that in humans is encoded by the MALT1 gene. It's the human paracaspase. # Function Genetic ablation of the paracaspase gene in mice and biochemical studies have shown that paracaspase is a crucial protein for T and B lymphocytes act...
MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 is a protein that in humans is encoded by the MALT1 gene.[1][2][3] It's the human paracaspase. # Function Genetic ablation of the paracaspase gene in mice and biochemical studies have shown that paracaspase is a crucial protein for T and B lymph...
https://www.wikidoc.org/index.php/MALT1
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wikidoc
MAML1
MAML1 Mastermind-like protein 1 is a protein that in humans is encoded by the MAML1 gene. # Function This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a comp...
MAML1 Mastermind-like protein 1 is a protein that in humans is encoded by the MAML1 gene.[1][2][3] # Function This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog fo...
https://www.wikidoc.org/index.php/MAML1
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wikidoc
MAP1B
MAP1B Microtubule-associated protein 1B is a protein that in humans is encoded by the MAP1B gene. # Function This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis....
MAP1B Microtubule-associated protein 1B is a protein that in humans is encoded by the MAP1B gene.[1][2] # Function This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurog...
https://www.wikidoc.org/index.php/MAP1B
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MAPK1
MAPK1 Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme that in humans is encoded by the MAPK1 gene. # Function The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration p...
MAPK1 Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme that in humans is encoded by the MAPK1 gene.[1] # Function The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integrati...
https://www.wikidoc.org/index.php/MAPK1
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wikidoc
MAPK3
MAPK3 Mitogen-activated protein kinase 3, also known as p44MAPK and ERK1, is an enzyme that in humans is encoded by the MAPK3 gene. # Function The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAP kinase) family. MAP kinases, also known as extracellular signal-regulated kinases (ERK...
MAPK3 Mitogen-activated protein kinase 3, also known as p44MAPK and ERK1,[1] is an enzyme that in humans is encoded by the MAPK3 gene.[2] # Function The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAP kinase) family. MAP kinases, also known as extracellular signal-regulated kinas...
https://www.wikidoc.org/index.php/MAPK3
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MAPK6
MAPK6 Mitogen-activated protein kinase 6 is an enzyme that in humans is encoded by the MAPK6 gene. The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases, also known as extracellular signal-regulated ...
MAPK6 Mitogen-activated protein kinase 6 is an enzyme that in humans is encoded by the MAPK6 gene.[1][2] The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases, also known as extracellular signal-reg...
https://www.wikidoc.org/index.php/MAPK6
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wikidoc
MAPK7
MAPK7 Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene. # Function MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as...
MAPK7 Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene.[1][2] # Function MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes ...
https://www.wikidoc.org/index.php/MAPK7
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MARCO
MARCO Macrophage receptor MARCO also known as macrophage receptor with collagenous structure (MARCO) is a protein that in humans is encoded by the MARCO gene. MARCO is a class A scavenger receptor that is found on particular subsets of macrophages. Scavenger receptors are pattern recognition receptors (PRRs) and are mo...
MARCO Macrophage receptor MARCO also known as macrophage receptor with collagenous structure (MARCO) is a protein that in humans is encoded by the MARCO gene.[1][2][3][4] MARCO is a class A scavenger receptor that is found on particular subsets of macrophages.[5][6][7] Scavenger receptors are pattern recognition recep...
https://www.wikidoc.org/index.php/MARCO
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wikidoc
MARK4
MARK4 MAP/microtubule affinity-regulating kinase 4 is an enzyme that in humans is encoded by the MARK4 gene. MARK4 belongs to the family of serine/threonine kinases that phosphorylate microtubule-associated proteins (MAP) causing their detachment from microtubules. Detachment thereby increases microtubule dynamics and ...
MARK4 MAP/microtubule affinity-regulating kinase 4 is an enzyme that in humans is encoded by the MARK4 gene.[1][2][3] MARK4 belongs to the family of serine/threonine kinases that phosphorylate microtubule-associated proteins (MAP) causing their detachment from microtubules.[4] Detachment thereby increases microtubule ...
https://www.wikidoc.org/index.php/MARK4
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MASTL
MASTL MASTL is an official symbol provided by HGNC for human gene whose official name is micro tubule associated serine/threonine kinase like. This gene is 32,1 kbps long. This gene is also known as GW, GWL, THC2, MAST-L, GREATWALL. This is present in mainly mammalian cells like human, house mouse, cattle, monkey, etc...
MASTL MASTL is an official symbol provided by HGNC for human gene whose official name is micro tubule associated serine/threonine kinase like. This gene is 32,1 kbps long. This gene is also known as GW, GWL, THC2, MAST-L, GREATWALL. This is present in mainly mammalian cells like human, house mouse, cattle, monkey, et...
https://www.wikidoc.org/index.php/MASTL
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wikidoc
MATR3
MATR3 Matrin-3 is a protein that in humans is encoded by the MATR3 gene. # Function The protein encoded by this gene is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. Two transcript variants encoding th...
MATR3 Matrin-3 is a protein that in humans is encoded by the MATR3 gene.[1][2] # Function The protein encoded by this gene is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. Two transcript variants enco...
https://www.wikidoc.org/index.php/MATR3
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wikidoc
Wrist
Wrist In human anatomy, the wrist is the flexible and narrower connection between the forearm and the palm. The wrist is essentially a double row of small short bones, called carpals, intertwined to form a malleable hinge. The wrist-joint (articulatio radiocarpea) is a condyloid articulation allowing three degrees of f...
Wrist Template:Infobox Anatomy Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] In human anatomy, the wrist is the flexible and narrower connection between the forearm and the palm. The wrist is essentially a double row of small short bones, called carpals, intertwined to form a malleable hinge. The wrist-joint (art...
https://www.wikidoc.org/index.php/MCP_joint
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wikidoc
MDGA2
MDGA2 MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2) is a human gene. It has previously been called MAMDC1. MDGA2 is located on chromosome 14. The gene has a homologue in rat and mouse, Mdga2, and investigations in rats have found that the gene is expressed in the central and peripheral nervous sy...
MDGA2 MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2) is a human gene. It has previously been called MAMDC1.[1] MDGA2 is located on chromosome 14. The gene has a homologue in rat and mouse, Mdga2,[2] and investigations in rats have found that the gene is expressed in the central and peripheral ner...
https://www.wikidoc.org/index.php/MDGA2
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MECOM
MECOM MDS1 and EVI1 complex locus protein EVI1 (MECOM) also known as ecotropic virus integration site 1 protein homolog (EVI-1) or positive regulatory domain zinc finger protein 3 (PRDM3) is a protein that in humans is encoded by the MECOM gene. EVI1 was first identified as a common retroviral integration site in AKXD ...
MECOM MDS1 and EVI1 complex locus protein EVI1 (MECOM) also known as ecotropic virus integration site 1 protein homolog (EVI-1) or positive regulatory domain zinc finger protein 3 (PRDM3) is a protein that in humans is encoded by the MECOM gene. EVI1 was first identified as a common retroviral integration site in AKXD...
https://www.wikidoc.org/index.php/MECOM
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MECP2
MECP2 MECP2 (methyl CpG binding protein 2) is a gene that encodes the protein MECP2. MECP2 appears to be essential for the normal function of nerve cells. The protein seems to be particularly important for mature nerve cells, where it is present in high levels. The MECP2 protein is likely to be involved in turning off ...
MECP2 MECP2 (methyl CpG binding protein 2) is a gene[1] that encodes the protein MECP2.[2] MECP2 appears to be essential for the normal function of nerve cells. The protein seems to be particularly important for mature nerve cells, where it is present in high levels. The MECP2 protein is likely to be involved in turni...
https://www.wikidoc.org/index.php/MECP2
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MED12
MED12 Mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae), also known as MED12, is a human gene found on the X chromosome. # Clinical significance Mutations in MED12 are responsible for at least two different forms of X-linked dominant mental retardation, Lujan-Fryns syndrome and FG syndrom...
MED12 Mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae), also known as MED12, is a human gene found on the X chromosome.[1] # Clinical significance Mutations in MED12 are responsible for at least two different forms of X-linked dominant mental retardation, Lujan-Fryns syndrome and FG syn...
https://www.wikidoc.org/index.php/MED12
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MED14
MED14 Mediator of RNA polymerase II transcription subunit 14 is an enzyme that in humans is encoded by the MED14 gene. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcript...
MED14 Mediator of RNA polymerase II transcription subunit 14 is an enzyme that in humans is encoded by the MED14 gene.[1][2][3] The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct ...
https://www.wikidoc.org/index.php/MED14
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wikidoc
MED15
MED15 Mediator of RNA polymerase II transcription subunit 15, also known as Gal11,Spt13 in yeast and PCQAP, ARC105, or TIG-1 in humans is a protein encoded by the MED15 gene. # Function MED15 is a general transcriptional cofactor of the mediator complex involved in RNA polymerase II dependent transcription, originall...
MED15 Mediator of RNA polymerase II transcription subunit 15, also known as Gal11,Spt13 in yeast and PCQAP, ARC105, or TIG-1 in humans is a protein encoded by the MED15 gene.[1] # Function MED15 is a general transcriptional cofactor of the mediator complex involved in RNA polymerase II dependent transcription, origi...
https://www.wikidoc.org/index.php/MED15
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wikidoc
MED17
MED17 Mediator of RNA polymerase II transcription subunit 17 is an enzyme that in humans is encoded by the MED17 gene. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcript...
MED17 Mediator of RNA polymerase II transcription subunit 17 is an enzyme that in humans is encoded by the MED17 gene.[1][2][3] The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct ...
https://www.wikidoc.org/index.php/MED17
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wikidoc
MED22
MED22 Mediator of RNA polymerase II transcription subunit 22 is an enzyme that in humans is encoded by the MED22 gene. # Function This gene is located in the surfeit gene cluster, a group of very tightly linked housekeeping genes that do not share sequence similarity. The gene is oriented in a head-to-head fashion wit...
MED22 Mediator of RNA polymerase II transcription subunit 22 is an enzyme that in humans is encoded by the MED22 gene.[1][2][3] # Function This gene is located in the surfeit gene cluster, a group of very tightly linked housekeeping genes that do not share sequence similarity. The gene is oriented in a head-to-head f...
https://www.wikidoc.org/index.php/MED22
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wikidoc
MED24
MED24 Mediator of RNA polymerase II transcription subunit 24 is an enzyme that in humans is encoded by the MED24 gene. # Function This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all...
MED24 Mediator of RNA polymerase II transcription subunit 24 is an enzyme that in humans is encoded by the MED24 gene.[1] # Function This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost...
https://www.wikidoc.org/index.php/MED24
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wikidoc
MED26
MED26 Mediator of RNA polymerase II transcription subunit 26 is an enzyme that in humans is encoded by the MED26 gene. It forms part of the Mediator complex. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work ...
MED26 Mediator of RNA polymerase II transcription subunit 26 is an enzyme that in humans is encoded by the MED26 gene.[1][2] It forms part of the Mediator complex. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factor...
https://www.wikidoc.org/index.php/MED26
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wikidoc
MED27
MED27 Mediator of RNA polymerase II transcription subunit 27 is an enzyme that in humans is encoded by the MED27 gene. It forms part of the Mediator complex. The ubiquitous expression of Med27 mRNA suggests a universal requirement for Med27 in transcriptional initiation. Loss of Crsp34/Med27 decreases amacrine cell num...
MED27 Mediator of RNA polymerase II transcription subunit 27 is an enzyme that in humans is encoded by the MED27 gene.[1][2] It forms part of the Mediator complex. The ubiquitous expression of Med27 mRNA suggests a universal requirement for Med27 in transcriptional initiation. Loss of Crsp34/Med27 decreases amacrine c...
https://www.wikidoc.org/index.php/MED27
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wikidoc
MED28
MED28 Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. It forms part of the Mediator complex. # Function Subunit Med28 of the Mediator may function as a scaffolding protein within Mediator by maintaining the stability of a submodule within the head module...
MED28 Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene.[1][2][3] It forms part of the Mediator complex. # Function Subunit Med28 of the Mediator may function as a scaffolding protein within Mediator by maintaining the stability of a submodule within the h...
https://www.wikidoc.org/index.php/MED28
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wikidoc
MEF2B
MEF2B Myocyte enhancer binding factor 2B (MEF2B) is a transcription factor part of the MEF2 gene family including MEF2A, MEF2C, and MEF2D. However, MEF2B is distant from the other three branches of MEF2 genes as it lacks the protein-coding Holliday junction recognition protein C-terminal (HJURP_C) region in vertebrates...
MEF2B Myocyte enhancer binding factor 2B (MEF2B) is a transcription factor part of the MEF2 gene family including MEF2A, MEF2C, and MEF2D.[1][2] However, MEF2B is distant from the other three branches of MEF2 genes as it lacks the protein-coding Holliday junction recognition protein C-terminal (HJURP_C) region in vert...
https://www.wikidoc.org/index.php/MEF2B
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wikidoc
MEF2C
MEF2C Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene. MEF2C is a transcription factor in the Mef2 family. # Genomics The gene is located at 5q14.3 on the minus (Crick) strand and is 200,723 bases in leng...
MEF2C Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene.[1][2] MEF2C is a transcription factor in the Mef2 family.[3][4] # Genomics The gene is located at 5q14.3 on the minus (Crick) strand and is 200,723 ...
https://www.wikidoc.org/index.php/MEF2C
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wikidoc
MESP2
MESP2 Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein that in humans is encoded by the MESP2 gene. # Function This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somite...
MESP2 Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein that in humans is encoded by the MESP2 gene.[1] # Function This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of so...
https://www.wikidoc.org/index.php/MESP2
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wikidoc
MEX3D
MEX3D Mex-3 homolog D (C. elegans), also known as MEX3D, is a protein that in humans is encoded by the MEX3D gene. # Function MEX3D is an RNA binding protein that interacts with AU-rich elements of Bcl-2. Upon binding, MEX3D has a negative regulatory action on Bcl-2 expression at the posttranscriptional level. # Stru...
MEX3D Mex-3 homolog D (C. elegans), also known as MEX3D, is a protein that in humans is encoded by the MEX3D gene.[1][2] # Function MEX3D is an RNA binding protein that interacts with AU-rich elements of Bcl-2. Upon binding, MEX3D has a negative regulatory action on Bcl-2 expression at the posttranscriptional level.[...
https://www.wikidoc.org/index.php/MEX3D
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wikidoc
MFGE8
MFGE8 Milk fat globule-EGF factor 8 protein (Mfge8), also known as lactadherin, is a protein which in humans is encoded by the MFGE8 gene. # Species distribution Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. # Function MFGE8 may function as a cell adhesion protein to connect smoo...
MFGE8 Milk fat globule-EGF factor 8 protein (Mfge8), also known as lactadherin, is a protein which in humans is encoded by the MFGE8 gene.[1][2] # Species distribution Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. # Function MFGE8 may function as a cell adhesion protein to conne...
https://www.wikidoc.org/index.php/MFGE8
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wikidoc
MFSD2
MFSD2 Major facilitator superfamily domain-containing protein 2 (MFSD2 or MFSD2A) -- also known as sodium-dependent lysophosphatidylcholine symporter 1 -- is a protein that in humans is encoded by the MFSD2A gene. MFSD2A is a membrane transport protein that is expressed in the endothelium of the blood–brain barrier (B...
MFSD2 Major facilitator superfamily domain-containing protein 2 (MFSD2 or MFSD2A) -- also known as sodium-dependent lysophosphatidylcholine symporter 1 -- is a protein that in humans is encoded by the MFSD2A gene.[1] MFSD2A is a membrane transport protein that is expressed in the endothelium of the blood–brain barrie...
https://www.wikidoc.org/index.php/MFSD2
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wikidoc
MFSD8
MFSD8 Major facilitator superfamily domain containing 8 also known as MFSD8 is a protein that in humans is encoded by the MFSD8 gene. MFSD8 is an atypical SLC, thus a predicted SLC transporter. It clusters phylogenetically to the Atypical MFS Transporter family 2 (AMTF2). # Function MFSD8 is a ubiquitous integral memb...
MFSD8 Major facilitator superfamily domain containing 8 also known as MFSD8 is a protein that in humans is encoded by the MFSD8 gene.[1] MFSD8 is an atypical SLC,[2][3] thus a predicted SLC transporter. It clusters phylogenetically to the Atypical MFS Transporter family 2 (AMTF2).[3] # Function MFSD8 is a ubiquitous ...
https://www.wikidoc.org/index.php/MFSD8
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wikidoc
MGST3
MGST3 Microsomal glutathione S-transferase 3 is an enzyme that in humans is encoded by the MGST3 gene. The MAPEG (Membrane-Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved the production of leukotrienes and prostaglandin E, important medi...
MGST3 Microsomal glutathione S-transferase 3 is an enzyme that in humans is encoded by the MGST3 gene.[1][2] The MAPEG (Membrane-Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved the production of leukotrienes and prostaglandin E, importa...
https://www.wikidoc.org/index.php/MGST3
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wikidoc
MIPEP
MIPEP Mitochondrial intermediate peptidase is an enzyme that in humans is encoded by the MIPEP gene. This protein is a critical component of human mitochondrial protein import machinery involved in the maturing process of nuclear coded mitochondrial proteins that with a mitochondrial translocation peptide, especially t...
MIPEP Mitochondrial intermediate peptidase is an enzyme that in humans is encoded by the MIPEP gene.[1] This protein is a critical component of human mitochondrial protein import machinery involved in the maturing process of nuclear coded mitochondrial proteins that with a mitochondrial translocation peptide, especial...
https://www.wikidoc.org/index.php/MIPEP
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wikidoc
MLANA
MLANA Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA o "MALENA" gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. ...
MLANA Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA o "MALENA" gene.[1] A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune syst...
https://www.wikidoc.org/index.php/MLANA
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wikidoc
MMP10
MMP10 Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene. # Function Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic devel...
MMP10 Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.[1][2] # Function Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryoni...
https://www.wikidoc.org/index.php/MMP10
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wikidoc
MMP14
MMP14 Matrix metalloproteinase-14 is an enzyme that in humans is encoded by the MMP14 gene. # Function Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as we...
MMP14 Matrix metalloproteinase-14 is an enzyme that in humans is encoded by the MMP14 gene.[1] # Function Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, a...
https://www.wikidoc.org/index.php/MMP14
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wikidoc
MMP17
MMP17 Matrix metalloproteinase-17 (MMP-17) also known as membrane-type matrix metalloproteinase 4 (MT-MMP 4) is an enzyme that in humans is encoded by the MMP17 gene. # Function Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes...
MMP17 Matrix metalloproteinase-17 (MMP-17) also known as membrane-type matrix metalloproteinase 4 (MT-MMP 4) is an enzyme that in humans is encoded by the MMP17 gene.[1][2] # Function Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological pr...
https://www.wikidoc.org/index.php/MMP17
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wikidoc
MMP20
MMP20 Matrix metalloproteinase-20 (MMP-20) also known as enamel metalloproteinase or enamelysin is an enzyme that in humans is encoded by the MMP20 gene. # Function Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as emb...
MMP20 Matrix metalloproteinase-20 (MMP-20) also known as enamel metalloproteinase or enamelysin is an enzyme that in humans is encoded by the MMP20 gene.[1][2] # Function Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such...
https://www.wikidoc.org/index.php/MMP20
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wikidoc
MMP27
MMP27 Matrix metallopeptidase 27 also known as MMP-27 is an enzyme which in humans is encoded by the MMP27 gene. # Structure MMP-27 was discovered and cloned in 1998 by Yang and Kurkinen. Initially compared to the so-called Chicken MMP (CMMP), MMP-27 actually shows very little sequence homology with this protease. Seq...
MMP27 Matrix metallopeptidase 27 also known as MMP-27 is an enzyme which in humans is encoded by the MMP27 gene.[1] # Structure MMP-27 was discovered and cloned in 1998 by Yang and Kurkinen.[2] Initially compared to the so-called Chicken MMP (CMMP), MMP-27 actually shows very little sequence homology with this protea...
https://www.wikidoc.org/index.php/MMP27
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wikidoc
MOCS1
MOCS1 Molybdenum cofactor biosynthesis protein 1 is a protein that in humans and other animals, fungi, and cellular slime molds, is encoded by the MOCS1 gene. Both copies of this gene are defective in patients with molybdenum cofactor deficiency, type A. Molybdenum cofactor biosynthesis is a conserved pathway leading t...
MOCS1 Molybdenum cofactor biosynthesis protein 1 is a protein that in humans and other animals, fungi, and cellular slime molds, is encoded by the MOCS1 gene.[1][2] [3] [4] Both copies of this gene are defective in patients with molybdenum cofactor deficiency, type A.[4] Molybdenum cofactor biosynthesis is a conserved...
https://www.wikidoc.org/index.php/MOCS1
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wikidoc
MOCS2
MOCS2 Molybdenum cofactor synthesis protein 2A and molybdenum cofactor synthesis protein 2B are a pair of proteins that in humans are encoded from the same MOCS2 gene. These two proteins dimerize to form molybdopterin synthase. # Function Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of...
MOCS2 Molybdenum cofactor synthesis protein 2A and molybdenum cofactor synthesis protein 2B are a pair of proteins that in humans are encoded from the same MOCS2 gene.[1][2][3] These two proteins dimerize to form molybdopterin synthase. # Function Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) con...
https://www.wikidoc.org/index.php/MOCS2
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wikidoc
MPV17
MPV17 Protein MPV17 is a protein that in humans is encoded by the MPV17 gene. It is a mitochondrial inner membrane protein, which has a so far largely unknown role in mtDNA maintenance. Protein MPV17 is expressed in human pancreas, kidney, muscle, liver, lung, placenta, brain and heart. Human MPV17 is the orthologue of...
MPV17 Protein MPV17 is a protein that in humans is encoded by the MPV17 gene.[1][2][3] It is a mitochondrial inner membrane protein, which has a so far largely unknown role in mtDNA maintenance. Protein MPV17 is expressed in human pancreas, kidney, muscle, liver, lung, placenta, brain and heart.[4] Human MPV17 is the ...
https://www.wikidoc.org/index.php/MPV17
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wikidoc
MRPL3
MRPL3 Mitochondrial ribosomal protein L3 is a protein that in humans is encoded by the MRPL3 gene. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subuni...
MRPL3 Mitochondrial ribosomal protein L3 is a protein that in humans is encoded by the MRPL3 gene.[1] Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S su...
https://www.wikidoc.org/index.php/MRPL3
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wikidoc
MRPS5
MRPS5 28S ribosomal protein S5, mitochondrial is a protein that in humans is encoded by the MRPS5 gene. # Function Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a...
MRPS5 28S ribosomal protein S5, mitochondrial is a protein that in humans is encoded by the MRPS5 gene.[1] # Function Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit a...
https://www.wikidoc.org/index.php/MRPS5
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wikidoc
MSTO1
MSTO1 Protein misato homolog 1 is a protein that in humans is encoded by the MSTO1 gene. The MSTO1 gene is 5134 base pairs (located in chromosome 1) and the MSTO1 protein is 570 aminoacids in length. It is located in the outer membrane of the mitochondrion, and is involved in the regulation of mitochondrial distributio...
MSTO1 Protein misato homolog 1 is a protein that in humans is encoded by the MSTO1 gene.[1][2] The MSTO1 gene is 5134 base pairs (located in chromosome 1) and the MSTO1 protein is 570 aminoacids in length. It is located in the outer membrane of the mitochondrion, and is involved in the regulation of mitochondrial dist...
https://www.wikidoc.org/index.php/MSTO1
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wikidoc
MT-TD
MT-TD Mitochondrially encoded tRNA aspartic acid also known as MT-TD is a transfer RNA which in humans is encoded by the mitochondrial MT-TD gene. # Structure The MT-TD gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 67 base pairs. The structure of a tRNA molecule is a distinctive fol...
MT-TD Mitochondrially encoded tRNA aspartic acid also known as MT-TD is a transfer RNA which in humans is encoded by the mitochondrial MT-TD gene.[1] # Structure The MT-TD gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 67 base pairs.[2] The structure of a tRNA molecule is a distinct...
https://www.wikidoc.org/index.php/MT-TD
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wikidoc
MT-TE
MT-TE Mitochondrially encoded tRNA glutamic acid also known as MT-TE is a transfer RNA which in humans is encoded by the mitochondrial MT-TE gene. MT-TE is a small 69 nucleotide RNA (human mitochondrial map position 14674-14742) that transfers the amino acid glutamic acid to a growing polypeptide chain at the ribosome ...
MT-TE Mitochondrially encoded tRNA glutamic acid also known as MT-TE is a transfer RNA which in humans is encoded by the mitochondrial MT-TE gene.[1] MT-TE is a small 69 nucleotide RNA (human mitochondrial map position 14674-14742) that transfers the amino acid glutamic acid to a growing polypeptide chain at the ribos...
https://www.wikidoc.org/index.php/MT-TE
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wikidoc
MT-TF
MT-TF Mitochondrially encoded tRNA phenylalanine also known as MT-TF is a transfer RNA which in humans is encoded by the mitochondrial MT-TF gene. # Structure The MT-TF gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 71 base pairs. The structure of a tRNA molecule is a distinctive fol...
MT-TF Mitochondrially encoded tRNA phenylalanine also known as MT-TF is a transfer RNA which in humans is encoded by the mitochondrial MT-TF gene.[1] # Structure The MT-TF gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 71 base pairs.[2] The structure of a tRNA molecule is a distinct...
https://www.wikidoc.org/index.php/MT-TF
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wikidoc
MT-TG
MT-TG Mitochondrially encoded tRNA glycine also known as MT-TG is a transfer RNA which in humans is encoded by the mitochondrial MT-TG gene. # Structure The MT-TG gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 68 base pairs. The structure of a tRNA molecule is a distinctive folded st...
MT-TG Mitochondrially encoded tRNA glycine also known as MT-TG is a transfer RNA which in humans is encoded by the mitochondrial MT-TG gene.[1] # Structure The MT-TG gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 68 base pairs.[2] The structure of a tRNA molecule is a distinctive fo...
https://www.wikidoc.org/index.php/MT-TG
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wikidoc
MT-TH
MT-TH Mitochondrially encoded tRNA histidine, also known as MT-TH, is a transfer RNA which, in humans, is encoded by the mitochondrial MT-TH gene. # Structure The MT-TH gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 69 base pairs. The structure of a tRNA molecule is a distinctive fol...
MT-TH Mitochondrially encoded tRNA histidine, also known as MT-TH, is a transfer RNA which, in humans, is encoded by the mitochondrial MT-TH gene.[1] # Structure The MT-TH gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 69 base pairs.[2] The structure of a tRNA molecule is a distinct...
https://www.wikidoc.org/index.php/MT-TH
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wikidoc
MT-TI
MT-TI Mitochondrially encoded tRNA isoleucine also known as MT-TI is a transfer RNA which in humans is encoded by the mitochondrial MT-TI gene. # Structure The MT-TI gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 69 base pairs. The structure of a tRNA molecule is a distinctive folded...
MT-TI Mitochondrially encoded tRNA isoleucine also known as MT-TI is a transfer RNA which in humans is encoded by the mitochondrial MT-TI gene.[1] # Structure The MT-TI gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 69 base pairs.[2] The structure of a tRNA molecule is a distinctive...
https://www.wikidoc.org/index.php/MT-TI
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wikidoc
MT-TK
MT-TK Mitochondrially encoded tRNA lysine also known as MT-TK is a transfer RNA which in humans is encoded by the mitochondrial MT-TK gene. # Structure The MT-TK gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 70 base pairs. The structure of a tRNA molecule is a distinctive folded str...
MT-TK Mitochondrially encoded tRNA lysine also known as MT-TK is a transfer RNA which in humans is encoded by the mitochondrial MT-TK gene.[1] # Structure The MT-TK gene is located on the p arm of the mitochondrial DNA at position 12 and it spans 70 base pairs.[2] The structure of a tRNA molecule is a distinctive fol...
https://www.wikidoc.org/index.php/MT-TK
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wikidoc
MT-TN
MT-TN Mitochondrially encoded tRNA asparagine also known as MT-TN is a transfer RNA which in humans is encoded by the mitochondrial MT-TN gene. # Structure The MT-TN gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 73 base pairs. The structure of a tRNA molecule is a distin...
MT-TN Mitochondrially encoded tRNA asparagine also known as MT-TN is a transfer RNA which in humans is encoded by the mitochondrial MT-TN gene.[1] # Structure The MT-TN gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 73 base pairs.[2] The structure of a tRNA molecule is a...
https://www.wikidoc.org/index.php/MT-TN
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wikidoc
MT-TP
MT-TP Mitochondrially encoded tRNA proline also known as MT-TP is a transfer RNA that in humans is encoded by the mitochondrial MT-TP gene. # Structure The MT-TP gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 68 base pairs. The structure of a tRNA molecule is a distinctiv...
MT-TP Mitochondrially encoded tRNA proline also known as MT-TP is a transfer RNA that in humans is encoded by the mitochondrial MT-TP gene.[1] # Structure The MT-TP gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 68 base pairs.[2] The structure of a tRNA molecule is a dis...
https://www.wikidoc.org/index.php/MT-TP
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wikidoc
MT-TR
MT-TR Mitochondrially encoded tRNA arginine also known as MT-TR is a transfer RNA which in humans is encoded by the mitochondrial MT-TR gene. # Structure The MT-TR gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 65 base pairs. The structure of a tRNA molecule is a distinct...
MT-TR Mitochondrially encoded tRNA arginine also known as MT-TR is a transfer RNA which in humans is encoded by the mitochondrial MT-TR gene.[1] # Structure The MT-TR gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 65 base pairs.[2] The structure of a tRNA molecule is a d...
https://www.wikidoc.org/index.php/MT-TR
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wikidoc
MT-TT
MT-TT Mitochondrially encoded tRNA threonine also known as MT-TT is a transfer RNA which in humans is encoded by the mitochondrial MT-TT gene. # Structure The MT-TT gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 66 base pairs. The structure of a tRNA molecule is a distinc...
MT-TT Mitochondrially encoded tRNA threonine also known as MT-TT is a transfer RNA which in humans is encoded by the mitochondrial MT-TT gene.[1] # Structure The MT-TT gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 66 base pairs.[2] The structure of a tRNA molecule is a ...
https://www.wikidoc.org/index.php/MT-TT
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wikidoc
MT-TW
MT-TW Mitochondrially encoded tRNA tryptophan also known as MT-TW is a transfer RNA which in humans is encoded by the mitochondrial MT-TW gene. # Structure The MT-TW gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 68 base pairs. The structure of a tRNA molecule is a distin...
MT-TW Mitochondrially encoded tRNA tryptophan also known as MT-TW is a transfer RNA which in humans is encoded by the mitochondrial MT-TW gene.[1] # Structure The MT-TW gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 68 base pairs.[2] The structure of a tRNA molecule is a...
https://www.wikidoc.org/index.php/MT-TW
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wikidoc
MT-TY
MT-TY Mitochondrially encoded tRNA tyrosine also known as MT-TY is a transfer RNA which in humans is encoded by the mitochondrial MT-TY gene. # Structure The MT-TY gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 66 base pairs. The structure of a tRNA molecule is a distinct...
MT-TY Mitochondrially encoded tRNA tyrosine also known as MT-TY is a transfer RNA which in humans is encoded by the mitochondrial MT-TY gene.[1] # Structure The MT-TY gene is located on the p arm of the non-nuclear mitochondrial DNA at position 12 and it spans 66 base pairs.[2] The structure of a tRNA molecule is a d...
https://www.wikidoc.org/index.php/MT-TY
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wikidoc
MTCH1
MTCH1 Mitochondrial carrier homolog 1 (MTCH1), also referred to as presenilin 1-associated protein (PSAP), is a protein that in humans is encoded by the MTCH1 gene on chromosome 6. MTCH1 is a proapoptotic mitochondrial protein potentially involved in Alzheimer’s disease (AD). # Structure The protein encoded by this ge...
MTCH1 Mitochondrial carrier homolog 1 (MTCH1), also referred to as presenilin 1-associated protein (PSAP), is a protein that in humans is encoded by the MTCH1 gene on chromosome 6.[1][2][3] MTCH1 is a proapoptotic mitochondrial protein potentially involved in Alzheimer’s disease (AD).[2][3][4] # Structure The protein...
https://www.wikidoc.org/index.php/MTCH1
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wikidoc
MTFMT
MTFMT Mitochondrial methionyl-tRNA formyltransferase is a protein that in humans is encoded by the MTFMT gene. The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA. Recessive-type mutations in MTFMT have been shown to cause mitochondrial disease. ...
MTFMT Mitochondrial methionyl-tRNA formyltransferase is a protein that in humans is encoded by the MTFMT gene.[1] The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA.[1] Recessive-type mutations in MTFMT have been shown to cause mitochondrial di...
https://www.wikidoc.org/index.php/MTFMT
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wikidoc
MTUS1
MTUS1 Mitochondrial tumor suppressor 1 (MTSG1) or Microtubule-Associated Scaffold Protein 1 (MTUS1) is a candidate tumor suppressor protein encoded by the MTUS1 gene in humans. Expression levels of MTUS1 was reported to be lost in various types of human malignancies such as colon, ovarian, head-and-neck, pancreas, brea...
MTUS1 Mitochondrial tumor suppressor 1 (MTSG1) or Microtubule-Associated Scaffold Protein 1 (MTUS1) is a candidate tumor suppressor protein encoded by the MTUS1 gene in humans.[1][2] Expression levels of MTUS1 was reported to be lost in various types of human malignancies such as colon, ovarian, head-and-neck, pancrea...
https://www.wikidoc.org/index.php/MTUS1
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wikidoc
MUS81
MUS81 Crossover junction endonuclease MUS81 is an enzyme that in humans is encoded by the MUS81 gene. In mammalian somatic cells, MUS81 and another structure specific DNA endonuclease, XPF (ERCC4), play overlapping and essential roles in completion of homologous recombination. The significant overlap in function betw...
MUS81 Crossover junction endonuclease MUS81 is an enzyme that in humans is encoded by the MUS81 gene.[1][2][3] In mammalian somatic cells, MUS81 and another structure specific DNA endonuclease, XPF (ERCC4), play overlapping and essential roles in completion of homologous recombination.[4] The significant overlap in ...
https://www.wikidoc.org/index.php/MUS81
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wikidoc
MUTED
MUTED Protein Muted homolog is a protein that in humans is encoded by the MUTED gene. # Function This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mous...
MUTED Protein Muted homolog is a protein that in humans is encoded by the MUTED gene.[1][2] # Function This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules....
https://www.wikidoc.org/index.php/MUTED
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wikidoc
MUTYH
MUTYH MUTYH (mutY DNA glycosylase) is a human gene that encodes a DNA glycosylase, MUTYH glycosylase. It is involved in oxidative DNA damage repair and is part of the base excision repair pathway. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytos...
MUTYH MUTYH (mutY DNA glycosylase) is a human gene that encodes a DNA glycosylase, MUTYH glycosylase. It is involved in oxidative DNA damage repair and is part of the base excision repair pathway. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cyto...
https://www.wikidoc.org/index.php/MUTYH
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wikidoc
MXRA5
MXRA5 Matrix-remodelling associated 5 is a protein in humans that is encoded by the MXRA5 gene. # Function This gene encodes one of the matrix-remodelling associated proteins. This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. This gene has a pseudogene on chro...
MXRA5 Matrix-remodelling associated 5 is a protein in humans that is encoded by the MXRA5 gene.[1] # Function This gene encodes one of the matrix-remodelling associated proteins. This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. This gene has a pseudogene on ...
https://www.wikidoc.org/index.php/MXRA5
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wikidoc
MYCBP
MYCBP C-Myc-binding protein is a protein that in humans is encoded by the MYCBP gene. # Function The MYCBP gene encodes a protein that binds to the N-terminal region of MYC (MIM 190080) and stimulates the activation of E box-dependent transcription by MYC. # Interactions MYCBP has been shown to interact with AKAP1, C...
MYCBP C-Myc-binding protein is a protein that in humans is encoded by the MYCBP gene.[1][2] # Function The MYCBP gene encodes a protein that binds to the N-terminal region of MYC (MIM 190080) and stimulates the activation of E box-dependent transcription by MYC.[supplied by OMIM][2] # Interactions MYCBP has been sho...
https://www.wikidoc.org/index.php/MYCBP
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wikidoc
MYD88
MYD88 Myeloid differentiation primary response 88 (MYD88) is a protein that, in humans, is encoded by the MYD88 gene. # Model organisms Model organisms have been used in the study of MYD88 function. The gene was originally discovered and cloned by Dan Liebermann and Barbara Hoffman in mice. In that species it is a uni...
MYD88 Myeloid differentiation primary response 88 (MYD88) is a protein that, in humans, is encoded by the MYD88 gene.[1][2] # Model organisms Model organisms have been used in the study of MYD88 function. The gene was originally discovered and cloned by Dan Liebermann and Barbara Hoffman in mice.[3] In that species i...
https://www.wikidoc.org/index.php/MYD88
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wikidoc
MYH10
MYH10 Myosin-10 also known as myosin heavy chain 10 or non-muscle myosin IIB (NM-IIB) is a protein that in humans is encoded by the MYH10 gene. Non-muscle myosins are expressed in a wide variety of tissues, but NM-IIB is the only non-muscle myosin II isoform expressed in cardiac muscle, where it localizes to adherens j...
MYH10 Myosin-10 also known as myosin heavy chain 10 or non-muscle myosin IIB (NM-IIB) is a protein that in humans is encoded by the MYH10 gene.[1][2] Non-muscle myosins are expressed in a wide variety of tissues, but NM-IIB is the only non-muscle myosin II isoform expressed in cardiac muscle, where it localizes to adh...
https://www.wikidoc.org/index.php/MYH10
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wikidoc
MYH11
MYH11 Myosin-11 is a protein that in humans is encoded by the MYH11 gene. # Function Gene ID: 4629 MYH11 myosin heavy chain 11, "The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain s...
MYH11 Associate Editor(s)-in-Chief: Henry A. Hoff Myosin-11 is a protein that in humans is encoded by the MYH11 gene.[1][2] # Function Gene ID: 4629 MYH11 myosin heavy chain 11, "The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a ...
https://www.wikidoc.org/index.php/MYH11
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wikidoc
MYLIP
MYLIP Myosin regulatory light chain interacting protein, also known as MYLIP, is a protein that in humans is encoded by the MYLIP gene. MYLIP is also known as IDOL "Inducible Degrader of the LDL receptor" based on its involvement in cholesterol regulation. The expression of IDOL is induced by the sterol-activated live...
MYLIP Myosin regulatory light chain interacting protein, also known as MYLIP, is a protein that in humans is encoded by the MYLIP gene.[1] MYLIP is also known as IDOL "Inducible Degrader of the LDL receptor" based on its involvement in cholesterol regulation.[2][3] The expression of IDOL is induced by the sterol-acti...
https://www.wikidoc.org/index.php/MYLIP
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wikidoc
MYLK2
MYLK2 Myosin light chain kinase 2 also known as MYLK2 is an enzyme which in humans is encoded by the MYLK2 gene. # Function This gene encodes a myosin light chain kinase, a calcium / calmodulin dependent enzyme, that is exclusively expressed in adult skeletal muscle. The MYLK2 gene expresses skMLCK more prevalently i...
MYLK2 Myosin light chain kinase 2 also known as MYLK2 is an enzyme which in humans is encoded by the MYLK2 gene.[1] # Function This gene encodes a myosin light chain kinase, a calcium / calmodulin dependent enzyme, that is exclusively expressed in adult skeletal muscle.[2] The MYLK2 gene expresses skMLCK more preval...
https://www.wikidoc.org/index.php/MYLK2
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wikidoc
MYLK4
MYLK4 Myosin light chain kinase 4 also known as MYLK4 is an enzyme which in humans is encoded by the MYLK2 gene. MYLK4 is a member of the myosin light-chain kinase family of serine/threonine-specific protein kinases that phosphorylate the regulatory light chain of myosin II. This protein acts as an enzyme that catalyz...
MYLK4 Myosin light chain kinase 4 also known as MYLK4 is an enzyme which in humans is encoded by the MYLK2 gene.[2] MYLK4 is a member of the myosin light-chain kinase family of serine/threonine-specific protein kinases that phosphorylate the regulatory light chain of myosin II.[3] This protein acts as an enzyme that ...
https://www.wikidoc.org/index.php/MYLK4
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wikidoc
MYO10
MYO10 Myosin X, also known as MYO10, is a protein that in humans is encoded by the MYO10 gene. Myosin X is an actin-based motor protein known to associate at the tips of filopodia. # Model organisms Model organisms have been used in the study of MYO10 function. A conditional knockout mouse line called Myo10tm2(KOMP)Wt...
MYO10 Myosin X, also known as MYO10, is a protein that in humans is encoded by the MYO10 gene.[1][2][3] Myosin X is an actin-based motor protein known to associate at the tips of filopodia.[4] # Model organisms Model organisms have been used in the study of MYO10 function. A conditional knockout mouse line called Myo...
https://www.wikidoc.org/index.php/MYO10
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wikidoc
MYO5A
MYO5A Myosin-Va is a protein that in humans is encoded by the MYO5A gene. # Interactions MYO5A has been shown to interact with DYNLL1, RAB27A, DYNLL2 and RPGRIP1L. # Clinical significance Defects are associated with Griscelli syndrome type 1, also known as Elejalde syndrome. # Model organisms Model organisms have be...
MYO5A Myosin-Va is a protein that in humans is encoded by the MYO5A gene.[1][2][3] # Interactions MYO5A has been shown to interact with DYNLL1,[4] RAB27A,[5][6] DYNLL2[4][7] and RPGRIP1L.[8] # Clinical significance Defects are associated with Griscelli syndrome type 1, also known as Elejalde syndrome. # Model organ...
https://www.wikidoc.org/index.php/MYO5A
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wikidoc
MYO5B
MYO5B Myosin-Vb is a protein that in humans is encoded by the MYO5B gene. Recent evidence suggests that Myosin VB is related to the creation of memories by actin-dependent trafficking of AMPA receptor containing recycling endosomes in dendritic spines. Mutations of MYO5B cause microvillus inclusion disease and have bee...
MYO5B Myosin-Vb is a protein that in humans is encoded by the MYO5B gene.[1][2][3] Recent evidence suggests that Myosin VB is related to the creation of memories[4] by actin-dependent trafficking of AMPA receptor containing recycling endosomes in dendritic spines.[5] Mutations of MYO5B cause microvillus inclusion dise...
https://www.wikidoc.org/index.php/MYO5B
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wikidoc
MYO7A
MYO7A Myosin VIIA is protein that in humans is encoded by the MYO7A gene. Myosin VIIA is a member of the unconventional myosin superfamily of proteins. Myosins are actin binding molecular motors that use the enzymatic conversion of ATP - ADP + inorganic phosphate (Pi) to provide the energy for movement. Myosins are me...
MYO7A Myosin VIIA is protein that in humans is encoded by the MYO7A gene.[1] Myosin VIIA is a member of the unconventional myosin superfamily of proteins.[2] Myosins are actin binding molecular motors that use the enzymatic conversion of ATP - ADP + inorganic phosphate (Pi) to provide the energy for movement. Myosins...
https://www.wikidoc.org/index.php/MYO7A
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wikidoc
MYOM1
MYOM1 Myomesin-1 is a protein that in humans is encoded by the MYOM1 gene. Myomesin-1 is expressed in muscle cells and functions to stabilize the three-dimensional conformation of the thick filament. Embryonic forms of Myomesin-1 have been detected in dilated cardiomyopathy. # Structure Alternatively spliced variants ...
MYOM1 Myomesin-1 is a protein that in humans is encoded by the MYOM1 gene.[1][2] Myomesin-1 is expressed in muscle cells and functions to stabilize the three-dimensional conformation of the thick filament. Embryonic forms of Myomesin-1 have been detected in dilated cardiomyopathy. # Structure Alternatively spliced va...
https://www.wikidoc.org/index.php/MYOM1
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wikidoc
MYOM2
MYOM2 M-protein, also known as Myomesin-2 is a protein that in humans is encoded by the MYOM2 gene. M-protein is expressed in adult cardiac muscle and fast skeletal muscle, and functions to stabilize the three-dimensional arrangement of proteins comprising M-band structures. # Structure Human M-protein is 165.0 kDa an...
MYOM2 M-protein, also known as Myomesin-2 is a protein that in humans is encoded by the MYOM2 gene.[1] M-protein is expressed in adult cardiac muscle and fast skeletal muscle, and functions to stabilize the three-dimensional arrangement of proteins comprising M-band structures. # Structure Human M-protein is 165.0 kD...
https://www.wikidoc.org/index.php/MYOM2
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wikidoc
MYOZ2
MYOZ2 Myozenin-2, also referred to as Calsarcin-1, is a protein that in humans is encoded by the MYOZ2 gene. The Calsarcin-1 isoform is a muscle protein expressed in cardiac muscle and slow-twitch skeletal muscle, which functions to tether calcineurin to alpha-actinin at Z-discs, and inhibit the pathological cardiac hy...
MYOZ2 Myozenin-2, also referred to as Calsarcin-1, is a protein that in humans is encoded by the MYOZ2 gene.[1][2][3] The Calsarcin-1 isoform is a muscle protein expressed in cardiac muscle and slow-twitch skeletal muscle, which functions to tether calcineurin to alpha-actinin at Z-discs, and inhibit the pathological ...
https://www.wikidoc.org/index.php/MYOZ2