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cardiac cycle : period of time between the onset of atrial contraction (atrial systole) and ventricular relaxation (ventricular diastole)
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
cardiac notch : depression in the medial surface of the superior lobe of the left lung where the apex of the heart is located
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
cardiac output (CO) : amount of blood pumped by each ventricle during one minute; equals HR multiplied by SV
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
cardiac plexus : paired complex network of nerve fibers near the base of the heart that receive sympathetic and parasympathetic stimulations to regulate HR
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
cardiac reflexes : series of autonomic reflexes that enable the cardiovascular centers to regulate heart function based upon sensory information from a variety of visceral sensors
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
cardiac reserve : difference between maximum and resting CO
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
cardiac skeleton : (also, skeleton of the heart) reinforced connective tissue located within the atrioventricular septum; includes four rings that surround the openings between the atria and ventricles, and the openings to the pulmonary trunk and aorta; the point of attachment for the heart valves
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
cardiogenic area : area near the head of the embryo where the heart begins to develop 18–19 days after fertilization
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
cardiogenic cords : two strands of tissue that form within the cardiogenic area
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
cardiomyocyte : muscle cell of the heart
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
chordae tendineae : string-like extensions of tough connective tissue that extend from the flaps of the atrioventricular valves to the papillary muscles
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
circumflex artery : branch of the left coronary artery that follows coronary sulcus
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
coronary arteries : branches of the ascending aorta that supply blood to the heart; the left coronary artery feeds the left side of the heart, the left atrium and ventricle, and the interventricular septum; the right coronary artery feeds the right atrium, portions of both ventricles, and the heart conduction system
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
coronary sinus : large, thin-walled vein on the posterior surface of the heart that lies within the atrioventricular sulcus and drains the heart myocardium directly into the right atrium
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
coronary sulcus : sulcus that marks the boundary between the atria and ventricles
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
coronary veins : vessels that drain the heart and generally parallel the large surface arteries
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
diastole : period of time when the heart muscle is relaxed and the chambers fill with blood
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
ejection fraction : portion of the blood that is pumped or ejected from the heart with each contraction; mathematically represented by SV divided by EDV
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
electrocardiogram (ECG) : surface recording of the electrical activity of the heart that can be used for diagnosis of irregular heart function; also abbreviated as EKG
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
end diastolic volume (EDV) : (also, preload) the amount of blood in the ventricles at the end of atrial systole just prior to ventricular contraction
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
end systolic volume (ESV) : amount of blood remaining in each ventricle following systole
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
endocardial tubes : stage in which lumens form within the expanding cardiogenic cords, forming hollow structures
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
endocardium : innermost layer of the heart lining the heart chambers and heart valves; composed of endothelium reinforced with a thin layer of connective tissue that binds to the myocardium
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
endothelium : layer of smooth, simple squamous epithelium that lines the endocardium and blood vessels
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
epicardial coronary arteries : surface arteries of the heart that generally follow the sulci
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
epicardium : innermost layer of the serous pericardium and the outermost layer of the heart wall
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
filling time : duration of ventricular diastole during which filling occurs
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
foramen ovale : opening in the fetal heart that allows blood to flow directly from the right atrium to the left atrium, bypassing the fetal pulmonary circuit
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
fossa ovalis : oval-shaped depression in the interatrial septum that marks the former location of the foramen ovale
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
Frank-Starling mechanism : relationship between ventricular stretch and contraction in which the force of heart contraction is directly proportional to the initial length of the muscle fiber
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
great cardiac vein : vessel that follows the interventricular sulcus on the anterior surface of the heart and flows along the coronary sulcus into the coronary sinus on the posterior surface; parallels the anterior interventricular artery and drains the areas supplied by this vessel
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
heart block : interruption in the normal conduction pathway
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
heart bulge : prominent feature on the anterior surface of the heart, reflecting early cardiac development
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
heart rate (HR) : number of times the heart contracts (beats) per minute
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
heart sounds : sounds heard via auscultation with a stethoscope of the closing of the atrioventricular valves (“lub”) and semilunar valves (“dub”)
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
hypertrophic cardiomyopathy : pathological enlargement of the heart, generally for no known reason
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
inferior vena cava : large systemic vein that returns blood to the heart from the inferior portion of the body
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
interatrial band : (also, Bachmann’s bundle) group of specialized conducting cells that transmit the impulse directly from the SA node in the right atrium to the left atrium
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
interatrial septum : cardiac septum located between the two atria; contains the fossa ovalis after birth
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
intercalated disc : physical junction between adjacent cardiac muscle cells; consisting of desmosomes, specialized linking proteoglycans, and gap junctions that allow passage of ions between the two cells
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
internodal pathways : specialized conductile cells within the atria that transmit the impulse from the SA node throughout the myocardial cells of the atrium and to the AV node
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
interventricular septum : cardiac septum located between the two ventricles
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
isovolumic contraction : (also, isovolumetric contraction) initial phase of ventricular contraction in which tension and pressure in the ventricle increase, but no blood is pumped or ejected from the heart
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
isovolumic ventricular relaxation phase : initial phase of the ventricular diastole when pressure in the ventricles drops below pressure in the two major arteries, the pulmonary trunk, and the aorta, and blood attempts to flow back into the ventricles, producing the dicrotic notch of the ECG and closing the two semilun...
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
left atrioventricular valve : (also, mitral valve or bicuspid valve) valve located between the left atrium and ventricle; consists of two flaps of tissue
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
marginal arteries : branches of the right coronary artery that supply blood to the superficial portions of the right ventricle
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
mesoderm : one of the three primary germ layers that differentiate early in embryonic development
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
mesothelium : simple squamous epithelial portion of serous membranes, such as the superficial portion of the epicardium (the visceral pericardium) and the deepest portion of the pericardium (the parietal pericardium)
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
middle cardiac vein : vessel that parallels and drains the areas supplied by the posterior interventricular artery; drains into the great cardiac vein
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
mitral valve : (also, left atrioventricular valve or bicuspid valve) valve located between the left atrium and ventricle; consists of two flaps of tissue
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
moderator band : band of myocardium covered by endocardium that arises from the inferior portion of the interventricular septum in the right ventricle and crosses to the anterior papillary muscle; contains conductile fibers that carry electrical signals followed by contraction of the heart
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
murmur : unusual heart sound detected by auscultation; typically related to septal or valve defects
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
myocardial conducting cells : specialized cells that transmit electrical impulses throughout the heart and trigger contraction by the myocardial contractile cells
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
myocardial contractile cells : bulk of the cardiac muscle cells in the atria and ventricles that conduct impulses and contract to propel blood
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
myocardium : thickest layer of the heart composed of cardiac muscle cells built upon a framework of primarily collagenous fibers and blood vessels that supply it and the nervous fibers that help to regulate it
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
negative inotropic factors : factors that negatively impact or lower heart contractility
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
P wave : component of the electrocardiogram that represents the depolarization of the atria
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pacemaker : cluster of specialized myocardial cells known as the SA node that initiates the sinus rhythm
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
papillary muscle : extension of the myocardium in the ventricles to which the chordae tendineae attach
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pectinate muscles : muscular ridges seen on the anterior surface of the right atrium
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pericardial cavity : cavity surrounding the heart filled with a lubricating serous fluid that reduces friction as the heart contracts
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pericardial sac : (also, pericardium) membrane that separates the heart from other mediastinal structures; consists of two distinct, fused sublayers: the fibrous pericardium and the parietal pericardium
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pericardium : (also, pericardial sac) membrane that separates the heart from other mediastinal structures; consists of two distinct, fused sublayers: the fibrous pericardium and the parietal pericardium
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
positive inotropic factors : factors that positively impact or increase heart contractility
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
posterior cardiac vein : vessel that parallels and drains the areas supplied by the marginal artery branch of the circumflex artery; drains into the great cardiac vein
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
posterior interventricular artery : (also, posterior descending artery) branch of the right coronary artery that runs along the posterior portion of the interventricular sulcus toward the apex of the heart and gives rise to branches that supply the interventricular septum and portions of both ventricles
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
posterior interventricular sulcus : sulcus located between the left and right ventricles on the posterior surface of the heart
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
preload : (also, end diastolic volume) amount of blood in the ventricles at the end of atrial systole just prior to ventricular contraction
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
prepotential depolarization : (also, spontaneous depolarization) mechanism that accounts for the autorhythmic property of cardiac muscle; the membrane potential increases as sodium ions diffuse through the always-open sodium ion channels and causes the electrical potential to rise
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
primitive atrium : portion of the primitive heart tube that eventually becomes the anterior portions of both the right and left atria, and the two auricles
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
primitive heart tube : singular tubular structure that forms from the fusion of the two endocardial tubes
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
primitive ventricle : portion of the primitive heart tube that eventually forms the left ventricle
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pulmonary arteries : left and right branches of the pulmonary trunk that carry deoxygenated blood from the heart to each of the lungs
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pulmonary capillaries : capillaries surrounding the alveoli of the lungs where gas exchange occurs: carbon dioxide exits the blood and oxygen enters
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pulmonary circuit : blood flow to and from the lungs
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pulmonary trunk : large arterial vessel that carries blood ejected from the right ventricle; divides into the left and right pulmonary arteries
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pulmonary valve : (also, pulmonary semilunar valve, the pulmonic valve, or the right semilunar valve) valve at the base of the pulmonary trunk that prevents backflow of blood into the right ventricle; consists of three flaps
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
pulmonary veins : veins that carry highly oxygenated blood into the left atrium, which pumps the blood into the left ventricle, which in turn pumps oxygenated blood into the aorta and to the many branches of the systemic circuit
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
Purkinje fibers : specialized myocardial conduction fibers that arise from the bundle branches and spread the impulse to the myocardial contraction fibers of the ventricles
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
QRS complex : component of the electrocardiogram that represents the depolarization of the ventricles and includes, as a component, the repolarization of the atria
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
right atrioventricular valve : (also, tricuspid valve) valve located between the right atrium and ventricle; consists of three flaps of tissue
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
semilunar valves : valves located at the base of the pulmonary trunk and at the base of the aorta
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
septum : (plural = septa) walls or partitions that divide the heart into chambers
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
septum primum : flap of tissue in the fetus that covers the foramen ovale within a few seconds after birth
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
sinoatrial (SA) node : known as the pacemaker, a specialized clump of myocardial conducting cells located in the superior portion of the right atrium that has the highest inherent rate of depolarization that then spreads throughout the heart
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
sinus rhythm : normal contractile pattern of the heart
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
sinus venosus : develops into the posterior portion of the right atrium, the SA node, and the coronary sinus
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
small cardiac vein : parallels the right coronary artery and drains blood from the posterior surfaces of the right atrium and ventricle; drains into the coronary sinus, middle cardiac vein, or right atrium
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
spontaneous depolarization : (also, prepotential depolarization) the mechanism that accounts for the autorhythmic property of cardiac muscle; the membrane potential increases as sodium ions diffuse through the always-open sodium ion channels and causes the electrical potential to rise
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
stroke volume (SV) : amount of blood pumped by each ventricle per contraction; also, the difference between EDV and ESV
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
sulcus : (plural = sulci) fat-filled groove visible on the surface of the heart; coronary vessels are also located in these areas
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
superior vena cava : large systemic vein that returns blood to the heart from the superior portion of the body
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
systemic circuit : blood flow to and from virtually all of the tissues of the body
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
systole : period of time when the heart muscle is contracting
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
T wave : component of the electrocardiogram that represents the repolarization of the ventricles
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
target heart rate : range in which both the heart and lungs receive the maximum benefit from an aerobic workout
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
trabeculae carneae : ridges of muscle covered by endocardium located in the ventricles
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
tricuspid valve : term used most often in clinical settings for the right atrioventricular valve
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
truncus arteriosus : portion of the primitive heart that will eventually divide and give rise to the ascending aorta and pulmonary trunk
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms
valve : in the cardiovascular system, a specialized structure located within the heart or vessels that ensures one-way flow of blood
https://openstax.org/books/anatomy-and-physiology-2e/pages/19-key-terms