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a central goal of genome wide association studies ( gwas ) is to identify genetic risk factors for complex disorders . in order to find the disease genetic risk factors in a population ,
gwas measures dna sequence variations across human genome ( bush and moore , 2012 ) .
practitioners in medical sciences and bioin... | genome - wide association studies the evaluation of association between candidate gene and disease status is widely carried out using cochran - armitage trend test .
however , only a small number of research papers have evaluated the distribution of p - values for the cochran - armitage trend test . in this paper , a... |
current recommendations for multidrug therapy ( mdt ) of leprosy follow a fixed duration of treatment regardless of clearance of skin lesions or presence or absence of acid - fast bacilli in the skin .
a fairly high percentage of patients with leprosy who complete recommended duration of multi - drug therapy are left... | background : current recommendations for multidrug therapy ( mdt ) of leprosy follow a fixed duration of treatment regardless of clearance of skin lesions or presence or absence of acid - fast bacilli in the skin .
a fairly high percentage of patients with leprosy who complete recommended duration of multi - drug the... |
although anterior cruciate ligament ( acl ) damage occurs most frequently in populations aged
1525 years participating in pivoting sports , it can occur in people of any age1 .
at least 80,000250,000 cases of acl damage
occur annually in the usa , and acl ruptures occur annually at a ratio of approximately one
... | [ purpose ] to examine changes in the knee joint s isokinetic muscle functions following
systematic and gradual rehabilitation exercises lasting for 12 weeks for male and female
patients who underwent anterior cruciate ligament ( acl ) reconstruction .
differences in
muscle functions between the uninvolved side... |
nasopharyngeal carcinoma ( npc ) is a major malignant disease of the head and neck region and is endemic to southeast asia and mediterranean basin , especially in southern china [ 1 , 2 ] . since npc originates from a hidden anatomical site and
is more closely associated with advanced clinical stage , the results of ... | cisplatin ( cddp ) is one of the most active drugs to treat nasopharyngeal carcinoma ( npc ) patients . to further understand the mechanisms of cddp - resistance in npc , two cddp - resistant sublines ( cne2-cddp and cne2-cddp-5fu ) derived from parental npc cell line cne2 were established .
it was found that at the ... |
reactive airways dysfunction syndrome ( rads ) is defined as the sudden onset of asthma - like symptoms following high - level exposure to a corrosive gas , vapor , or fumes .
the term rads was originally described by brooks and lockers in 19811 as nonimmunological asthma resulting from exposure to an irritant gas . ... | reactive airways dysfunction syndrome is a controversial and poorly understood condition produced by inhalational injury from gas , vapors , or fumes .
the symptoms mimic asthma , but appear unresponsive to asthma treatments . if symptoms persist for more than 6 months , there is a risk that they can become chronic .... |
the dentigerous cyst is the most common type of noninflammatory odontogenic cyst and the most common cause of a pericoronal area of lucency associated with an impacted tooth .
the dentigerous cyst develops around an unerupted tooth by accumulation of fluid between the reduced enamel epithelium and the enamel .
it h... | dentigerous cyst is a developmental odontogenic cyst , which develops by accumulation of fluid between reduced enamel epithelium and the tooth crown of an unerupted tooth .
dentigerous cysts are usually solitary , slow growing , asymptomatic lesions that are incidentally found during routine radiographs they most fre... |
mucosal infections by candida albicans and related non - albicans candida species are some of the most frequently encountered infections in modern medicine .
oral thrush and vulvovaginal candidiasis ( vvc ) amass the largest numbers of incidences among mucocutaneous candida infections . while most forms of candidiasi... | candida albicans is the most important candida species causing vulvovaginal candidiasis ( vvc ) .
vvc has significant medical and economical impact on women 's health and wellbeing . while current antifungal treatment is reasonably effective , supportive and preventive measures such as application of probiotics
are... |
seizures lie among prevalent diseases of childhood and occur in 10% of children . in the emergency
setting , the intravenous route is considered as the most suitable method , delivering adequate quantities of benzodiazepines in a short time . however ,
when intravenous administration is not available , other forms ... | objectivethe purpose of the present study is to compare efficacy and safety of buccal midazolam with intravenous diazepam in control of seizures in iranian children.methodsthis is a randomized clinical trial .
92 patients with acute seizures , ranging from 6 months to 14 years were randomly assigned to receive either... |
a 49-year - old , nonsmoking female had been treated for aml with one course of induction chemotherapy with the use of daunorubicin and cytosine arabinoside ( ara - c ) .
after relapse of aml , the patient was treated with 10 mg / m iv mitoxantrone daily for six days and 3 g / m iv ara - c , daily for six days . on d... | the radiological appearance of diffuse discrete pulmonary nodules associated with cryptogenic organizing pneumonia ( cop ) has been rarely described .
we describe a case of cop in 49-year - old woman with acute myeloid leukemia who developed diffuse pulmonary nodules during the second course of induction chemotherapy... |
although a richly vascularized organ with important circulatory communications , the penis is seldom the site of metastases . since eberth first reported it in 1870 there have been approximately 300 cases in the english language literature .
the primary tumour sites are principally the genitourinary organs , mainly t... | penile metastases are rare in colorectal cancer .
we report the first case of such a recurrence in a patient who had undergone an extralevator abdominoperineal resection with vertical rectus abdominis myocutaneous flap perineal reconstruction .
the patient was treated with curative intent by total penectomy . |
as the demand for adult orthodontic treatment increases and the popularity of esthetic dentistry expands , orthodontists are more likely faced with the problem of placing orthodontic appliances on teeth restored with resin and porcelain fixed prostheses or veneer laminates . when esthetics is a concern , orthodontists ... | objective : the aim of this study was to evaluate the bond strength between metal brackets and non - glazed ceramic with three different surface treatment methods.materials and methods : forty - two non - glazed ceramic disks were assigned into three groups .
group i and ii specimens were etched with 9.5% hydrofluori... |
tissue specimens were sent to the national reference center ( marseilles , france ) either frozen or in transport media .
csd was definitively diagnosed when a specimen was positive for 2 genes of bartonella spp ( 1 ) .
total genomic dna was extracted from samples by using a qiaamp tissue kit ( qiagen , hilden , ge... | cat - scratch disease is seasonal in the united states and japan ; but no data are available from europe . to assess the seasonality of the disease in france , we analyzed lymph node biopsy specimens collected during 19992009 .
most ( 87.5% ) cases occurred during september april and peaked in december . |
these benign cysts are located at the right cardiophrenic angle in 70% of cases , left cardiophrenic angle in 22% of cases and rarely in the posterior or anterior superior part of the mediastinum in 8% of cases ( 2 ) .
most of pericardial cysts ( > 50% ) are asymptomatic ( 1 , 3 ) and have a benign natural course . s... | pericardial cysts are rare lesions .
these benign anomalies are located in the middle mediastinum . in this article , we present a 24-year - old man who was referred to the emergency department with dyspnea and persistent cough . in physical exam , no abnormality was found .
his past medical history was normal .
... |
between 1996 and 2011 , all patients who underwent endovascular treatment via facial venous embolization for davf were identified from the neurointerventional database of three hospitals . clinical outcomes and radiologic findings of all patients with davf treated with transvenous embolization via fv
the dosage of he... | purposethe aim of this study was to evaluate the feasibility and safety of the transfacial venous embolization of cavernous or paracavernous dural arteriovenous fistula ( davf ) in which approach via inferior petrosal sinus ( ips ) was not feasible.materials and methodswe identified the cases of transfacial venous embo... |
the personal and professional development ( ppd ) module was introduced as a part of the medical curriculum , in september 2006 , along with other curricular changes , to ensure that students not only grow professionally into good doctors , but also grow personally . in order to offer our students a humane and holistic... | the study aimed at evaluating the personal and professional development ( ppd ) module in the undergraduate medical curriculum in melaka manipal medical college , india .
ppd hours were incorporated in the curriculum .
a team of faculty members and a faculty coordinator identified relevant topics and students were ... |
about ten years ago , we hypothesised that grasping is controlled as the independent movements of digits towards positions on an object s surface ( smeets and brenner 1999 ) .
in this view , the curved paths ( i.e. the opening and closing of the grip ) emerge because the digits tend to approach the surface perpendicu... | in order to find out whether the movements of single digits are controlled in a special way when grasping , we compared the movements of the digits when grasping an object with their movements in comparable single - digit tasks : pushing or lightly tapping the same object at the same place .
the movements of the digi... |
voltage - gated cation
( e.g. , na , k ) channels
are central to neurological signal transmission .
x - ray
crystal structures of the open state of several voltage - gated potassium
( kv ) channels and a sodium ( nav ) channel have
recently been determined .
kv channels
are composed of four identical su... | the
voltage sensor domain ( vsd ) of voltage - gated cation ( e.g. ,
na+ , k+ ) channels central to neurological signal
transmission can function as a distinct module . when linked to an
otherwise voltage - insensitive , ion - selective membrane pore
, the vsd
imparts voltage sensitivity to the channel .
... |
on september 23 , 2014 , a healthcare worker was admitted to mengo hospital in kampala , uganda , with a febrile illness suspected to be viral hemorrhagic fever ( vhf ) .
the patient , a 30-year - old man , was a radiographer who worked at mengo hospital and part - time at mpigi health center iv in the mpigi district... | in september 2014 , a single fatal case of marburg virus was identified in a healthcare worker in kampala , uganda .
the source of infection was not identified , and no secondary cases were identified .
we describe the rapid identification , laboratory diagnosis , and case investigation of the third marburg virus o... |
we analyzed 12 neuronal datasets recorded from two human clinical trial participants with tetraplegia ( hs1 and hs3 ) and four monkeys ( mla , mcl , mco and mab ) .
these included m1 recordings taken while human participants performed two sessions of a neural cursor center - out task ( that is , a task where the par... | coordinated spiking activity in neuronal ensembles , in local networks and across multiple cortical areas , is thought to provide the neural basis for cognition and adaptive behavior .
examining such collective dynamics at the level of single neuron spikes has remained , however , a considerable challenge .
we foun... |
not all of these inductions result in vaginal delivery , and some result in emergency cesarean sections . compared with spontaneous onset of labor , induction of labor
is complicated by a higher rate of cesarean section , occurring in one - fifth of women who undergo induction.1,2 an issue of interest for reproductiv... | background : reproductive health researchers are interested in finding better methods for predicting an unwanted type of delivery after induction of labor .
the aim of this study was to compare the value of transvaginal ultrasonography findings and the bishop score in predicting cesarean section after induction of la... |
a 9-month - old boy ( weight : 9 kg , height : 70.5 cm ) was brought into our emergency department with a complaint of vomiting .
his past medical history included a repair of a congenital diaphragmatic hernia 8 months prior .
chest radiography showed left lung haziness with pleural effusion and gaseous distended b... | video - assisted thoracoscopic surgery for pediatric patients has gained popularity due to better outcomes than open surgery . for this procedure
, one - lung ventilation may be necessary to provide an adequate surgical field . confirming lung isolation is crucial when one - lung ventilation is required .
recently ... |
tumor lysis syndrome ( tls ) is an oncologic emergency that frequently occurs in patients with a rapidly proliferating malignancy , commonly hematologic , after the initiation of cytotoxic therapy .
tls is characterized by a massive release of intracellular potassium , phosphate , and nucleic acid metabolites into th... | tumor lysis syndrome is an oncologic emergency that usually occurs after chemotherapy in patients with hematologic malignancies .
tumor lysis syndrome is rare in cases of solid tumors , especially when it occurs spontaneously .
herein , we present a case of spontaneous tumor lysis syndrome in a 55-year - old woman ... |
early risk stratification is essential in the management of patients with suspected or confirmed acute coronary syndrome .
traditionally , risk stratification involves an evaluation of medical history , a physical examination , and electrocardiography ( ecg ) upon admission . in recent years
, additional variables ... | background and objectivesthe prognostic value of biochemical markers and the resolution of st - segment elevation on electrocardiogram are well established .
however , how a combination of these two tools affects the evaluation of risk stratification has not yet been evaluated.subjects and methodsbetween january 2006... |
isotope
exchange depth profiling and electrochemical impedance
spectroscopy are usually regarded as complementary tools for measuring
the surface oxygen exchange activity of mixed conducting oxides , for
example used in solid oxide fuel cell ( sofc ) electrodes . only very
few studies compared electrical ( kq... | |
a quicker return to function , earlier discharge from the hospital , less postoperative pain , and better cosmesis due to the smaller incisions have been reported by multiple authors . decreased intraoperative blood loss and transfusion requirements have also been described .
laparoscopic splenectomy for splenic trau... | we describe the first reported use of laparoscopic splenectomy as initial treatment in high - grade blunt splenic trauma .
a 21-year - old man sustained a blow to the left flank from a large construction pipe and was transferred to our hospital with a grade v splenic laceration and a grade ii left peri - renal hemato... |
harmonization of biobanking operational procedures and best practices is an essential
element that enables biobanks to exchange and pool data and samples .
this so - called
interoperability is the foundation of successful global biobanking . rather than demanding
complete uniformity among biobanks , harmonizati... | biobanks can have a pivotal role in elucidating disease etiology , translation , and
advancing public health .
however , meeting these challenges hinges on a critical shift in
the way science is conducted and requires biobank harmonization .
there is growing
recognition that a common strategy is imperative to... |
alzheimer s disease ( ad ) is the most common type of dementia , but a cure for ad has yet to be discovered .
however , it may be possible to prevent or delay the onset of ad by reducing modifiable risks .
education has been proposed as a protective factor that can reduce the risk of developing dementia .
the pro... | introductionthe aim of this study was to determine whether years of schooling influences regional cortical thicknesses and volumes in alzheimer s disease ( ad ) , mild cognitive impairment ( mci ) , and healthy age - matched controls.methodsusing an automated image analysis pipeline , 33 regional cortical thickness and... |
mutations and substitutions are fundamental changes in nucleotide sequence over evolutionary time ( 1 ) . among the well - established methods for studying the evolution of protein - coding genes ,
the ratio of non - synonymous substitution rate ( ka , amino acid replacing ) to synonymous substitution rate ( ks , sil... | we present a bioinformatic web server ( swakk ) for detecting amino acid sites or regions of a protein under positive selection .
it estimates the ratio of non - synonymous to synonymous substitution rates ( ka / ks ) between a pair of protein - coding dna sequences , by sliding a 3d window , or sphere , across one r... |
to assess local prevalence of b. microti in host - seeking nymphal i. ricinus ticks , we developed a tick - sampling procedure with high spatial resolution ( figure 1 ) .
the roughly rectangular , 0.7-ha field site , ruetiwis ( 9 38 e , 46 59 n ) , is located on a steep southwesterly slope near seewis in the lower ... | we evaluated human risk for infection with babesia microti at a site in eastern switzerland where several b. microti infected nymphal ixodes ricinus ticks had been found .
dna from pooled nymphal ticks amplified by polymerase chain reaction was highly homologous to published b. microti sequences .
more ticks carri... |
cervical myelopathy with herniated discs is considered a degenerative process and many cases are diagnosed in older patients .
however , patients presenting in late adolescence with cervical myelopathy without any underlying disease are rare .
neurological deficit symptoms , including intractable radicular pain , l... | abstractreports on adolescent patients with cervical myelopathy who underwent anterior cervical discectomy and fusion are scarce . however , to our knowledge , no cases of expansive laminoplasty for cervical myelopathy associated with progressive neurological deficit after a series of conservative treatment , caused by... |
nosocomial infections ( hospital - acquired infections ) are becoming a major problem in the hospitals due to increase in morbidity , mortality , and cost associated with them .
ventilator - associated pneumonia ( vap ) is defined as hospital - acquired pneumonia which occurs within 48 - 72 h after endotracheal ( et ... | background : secretions contaminated with oral , nasal , and gastric bacteria accumulate in the subglottic space , above the endotracheal tube cuff .
if these secretions are aspirated into lower airways , the intubated patient will be susceptible to ventilator - associated pneumonia ( vap ) .
the aim of this study ... |
although the regulatory mechanisms of autophagy are partially known , the exact function of autophagy in cancer is still controversial . when analyzing the intricate relationship between autophagy and cancer , a common challenge is to determine whether autophagy protects cell survival or contributes to cell death .
t... | autophagy , an evolutionarily conserved lysosomal degradation process , has drawn an increasing amount of attention in recent years for its role in a variety of human diseases , such as cancer .
notably , autophagy plays an important role in regulating several survival and death signaling pathways that determine cell... |
wilms ' tumor is the second most common solid neoplasm and the most common malignant renal tumor in childhood affecting 1/1,000 of children12 ) .
survival correlates with tumor histology , as children , with favorable tumor histology have good survival rates despite widespread disease ( 5-year survival rate is over 8... | wilms ' tumor is the most common malignant renal tumor in childhood .
the brain metastasis of a wilms ' tumor with anaplastic histopathology is rare .
we present the case of an 8-year - old girl with wilms ' tumor , who presented with multiple brain metastases 5 years after her primary diagnosis .
the brain masse... |
injury of the anterior cruciate ligament ( acl ) is a common finding in orthopedic practice .
accurate diagnosis of this entity may be difficult , however it is essential to implement adequate treatment in order to avoid secondary damages to the knee joint.12 anterior knee instability is one of the symptoms of comple... | background : although ultrasound ( us ) has a wide range of applications in orthopedic diagnostics , sonographic evaluation of traumatic anterior cruciate ligament ( acl ) insufficiency is still inadequate .
there is a growing need for diagnostic tests that allow for simple and reliable assessment of acl instability ... |
behet 's disease ( bd ) is a chronic , relapsing , multisystem inflammatory disorder of unknown etiology , which is classified among the vasculitides.1 the cause of bd remains unknown ; however , an autoimmune reaction triggered by an infectious agent in a genetically predisposed individual has been suggested .
recur... | behet 's disease ( bd ) is a systemic vasculitis , while myelodysplastic syndrome ( mds ) is a heterogeneous group of clonal hematologic disorders characterized by ineffective hematopoiesis .
some studies suggest a relationship between mds and bd , especially intestinal bd , and trisomy 8 seems to play an important r... |
malakoplakia is an uncommon but distinctive type of chronic granulomatous inflammation that is characterized histologically by the presence of sheets of histiocytes with granular cytoplasm ( von hansemann cells ) admixed with intracellular and extracellular basophilic laminated inclusions ( michaelis - gutmann bodies )... | malacoplakia is a chronic inflammatory disease .
the disease mainly affects the urinary bladder , although involvement of extravesical sites is increasingly being documented .
most frequently involved is the urinary tract , particularly the urinary bladder , although the testis , epididymis , lungs , bone , colon ,... |
impairments in affect recognition have been found in individuals with adhd across the lifespan ( corbett and glidden , 2000 ; kats - gold et al . , 2007 ; rapport et al . , 2002 ) and shown to impact cognitive control in children with adhd ( kochel et al . , 2014 ) .
these basic emotion deficits have been linked to a... | affect recognition deficits found in individuals with attention - deficit / hyperactivity disorder ( adhd ) across the lifespan may bias the development of cognitive control processes implicated in the pathophysiology of the disorder .
this study aimed to determine the mechanism through which facial expressions influ... |
mammary gland disorders were first described by an ancient surgeon , imhotep , in a papyrus dated to the 17 century bc .
the author described 45 cases of this type , with a final conclusion of no cure presented along with the last case in the series . for more than 3000 years , breast cancer was a mysterious , abas... | recent years have witnessed a dynamic development of mammary gland imaging techniques , particularly ultrasonography and magnetic resonance imaging .
a challenge related to these studies is the increase in the precision of the anatomical assessment of breast , particularly for early detection of subclinical lesions ,... |
camp - protein kinase a a kinase anchoring protein a kinase binding domain cyclic adenosine monophosphate inositol triphosphate human chorionic gonadotropin mitogen - activated protein kinase proto - oncogene tyrosine - protein kinase
the camp - dependent protein kinase ( pka ) signaling pathway is characterized in d... | anchored protein kinase a ( pka ) bound to a kinase anchoring protein ( akap ) mediates effects of localized increases in camp in defined subcellular microdomains and retains the specificity in camp - pka signaling to distinct extracellular stimuli .
gap junctions are pores between adjacent cells constituted by conne... |
rapid development has been achieved in the construction of discrete and extended molecular architectures by selfassembly processes.1 such derivatives can be classified as inorganicorganic supramolecular complexes as they are usually obtained from twocomponent reactions involving the coordination of organic ligands be... | the threecomponent reaction of the tetrahedral diphosphorus complex [ cp2mo2(co)4(2p2 ) ] ( 1 ) , with ag[bf4 ] ( 2 ) in the presence of 2,2bipyrimidine ( 3 ) leads to the formation of the two novel twodimensional networks 4 and 5 .
compound 4 is a new twodimensional organometallicorganic hybrid polymer , while deriv... |
dementia causes a high burden of suffering for patients and their families ( boustani et al 2003a ) . for patients , in addition to cognitive and functional deterioration
, dementia leads to behavioral and psychological complications , increased use of health and social services , complicated clinical management of o... | most patients with dementia receive care within primary care systems and have challenging medical and psychiatric issues .
their dementia related symptoms are often not recognized by the primary care system ; they suffer from multiple chronic medical conditions ; receive numerous psychotropic medications including an... |
traditional healers play an important role in health care delivery system , particularly for the primary health care , in rural parts of india .
many of these traditional herbal health practices are popular among the community and claimed to be effective . however , most of these formulations are not scientifically s... | background : the herbal formulation consisting of andrographis paniculata nees . , cassia fistula l. , foeniculum vulgare mill . and cuminum cyminum l. is widely used by the local traditional practitioners in rural northern karnataka for spasmodic abdominal pain.objective:the present study was undertaken to evaluate sa... |
bleeding gastric gastric varices ( gvs ) carry a higher morbidity and mortality than bleeding esophageal varices ( evs ) , which are easier to access and treat endoscopically using banding .
balloon occluded retrograde transvenous obliteration ( brto ) of gvs is a minimally invasive treatment for such cases which rel... | approximately one in six patients with portal hypertension who develop varices at sites of portosystemic venous collaterals has gastric varices due to hepatofugal flow into the gastric veins . bleeding from gastric varices , though less common ,
has a higher mortality and morbidity compared to bleeding esophageal var... |
mucosal surfaces are constantly exposed to the external environment , which includes commensal microbes and exogenous antigens .
when pathogenic microbes breach the surface barrier , surveillance systems beneath sense the trespassers and send an alarm to defense headquarters .
mucosal immune tissues comprise lympho... | innate immune cells survey antigenic materials beneath our body surfaces and provide a front - line response to internal and external danger signals .
dendritic cells ( dcs ) , a subset of innate immune cells , are critical sentinels that perform multiple roles in immune responses , from acting as principal modulator... |
contrastinduced nephropathy ( cin ) is the third most common cause of hospitalacquired kidney injury , which contributes to decreased mobility and motility , prolonged hospitalization , and increased healthcare costs . identifying patients at risk of cin
easily and accurately would allow the administration of prophyl... | backgroundnterminal probrain natriuretic peptide ( ntprobnp ) has been associated with important risk factors for contrastinduced nephropathy ( cin ) .
however , few studies have investigated the predictive value of ntprobnp itself .
this study investigated whether levels of preprocedural ntprobnp could predict cin... |
a manifestation of severe insulin resistance , rabson - mendenhall syndrome presents with florid metabolic , cutaneous and systemic features thereby revealing the manifold effects of insulin on metabolism .
first described by rabson and mendenhall in 1956 in three siblings presenting with dental and skin abnormalitie... | rabson - mendenhall syndrome ( rms ) is a rare genetic disorder characterized by growth retardation , dysmorphisms , lack of subcutaneous fat , acanthosis nigricans , enlarged genitalia , hirsutism , dysplastic dentition , coarse facial features , abnormal glucose homeostasis , hyperinsulinemia and pineal hyperplasia .... |
the mouse epidermal jb6 cell system consists of clonal genetic variants that are sensitive ( p+ ) or resistant ( p- ) to the promotion of neoplastic transformation by phorbol esters and other tumor - promoting agents .
p+ cells display ap-1-dependent phorbol - ester - inducible transactivation of gene expression , wh... | |
biologic agents specifically target cytokines or surface structures to counteract pathogenic immune activation . due to their high specificity , they usually neither exhibit organ toxicities nor inhibit other processes or interact with other drugs , even in high dosages .
apart from the standard dose recommendations ... | biologics are highly specific and exhibit few problems in regard to overdosages . in clinical practice ,
induction schemes with an initial loading dose and a subsequent lower maintenance dose have been established and are of higher efficacy for psoriasis than starting directly with the maintenance dose . as obese pat... |
the pediatric emergency care applied research network ( pecarn ) is a research collaboration of pediatric emergency departments ( eds ) across the united states focusing on the care of acutely ill and injured children . recognizing the need to generate definitive evidence to inform the treatment of acutely ill and inju... | in this article , we review the history and progress of a large multicenter research network pertaining to emergency medical services for children . we describe the history , organization , infrastructure , and research agenda of the pediatric emergency care applied research network ( pecarn ) , and highlight some of t... |
adequate function of the extensor mechanism after total knee arthroplasty ( tka ) is essential for a successful clinical outcome as well as participation in daily living activities12 ) .
quadriceps strength is the major determinant of extensor mechanism function , which is affected by a variety of factors in tka .
... | purposealthough single - radius ( sr ) designs have a theoretical advantage in quadriceps recovery following total knee arthroplasty ( tka ) , there has been a paucity of objective evaluation studies.materials and methodsone hundred and twenty minimally invasive tkas were prospectively randomized by a single surgeon in... |
population aging is occurring in all the major areas of the world ; globally , the share of older people ( 60 years and older ) increased from 9% in 1994 to 12% in 2014 , and it is expected to reach 21% by 2050.1 there are critically important issues related to the aging society , such as future intergenerational relat... | introductionaging is not only a population phenomenon but also an experience and an individual reality .
vital aging is a program that considers active aging as the lifelong adaptation process of maximizing health and independence , physical and cognitive functioning , positive affect regulation and control , and soc... |
huntington s disease ( hd ) is a fatal , inherited neurodegenerative disorder characterized by progressive movement characterized by progressive motor , cognitive , and psychiatric symptoms .
while clinical diagnosis typically depends on motor abnormalities , predictive genetic testing of patients with hd has shown t... | the aim of this study was to describe the effects of varenicline , a smoking cessation aid that acts as a nicotinic agonist , on cognitive function in patients with early clinical huntington s disease ( hd ) who were current smokers .
three gene - positive patients transitioning to symptomatic hd were evaluated using... |
the healthy balance of normal processes in the lungs , termed pulmonary homeostasis , can be disturbed by external environmental insults or endogenous factors produced during other diseases . in response to insults , the lung responds with an ancient protective mechanism , inflammation .
the subsequent course of even... | cytokines are small , secreted proteins that control immune responses . within the lung
, they can control host responses to injuries or infection , resulting in clearance of the insult , repair of lung tissue , and return to homeostasis .
problems can arise when this response is over exuberant and/or cytokine prod... |
monoclonal gammopathy represents single plasma cell activation and is usually associated with several malignant diseases , including multiple myeloma , primary systemic amyloidosis , and other lymphoproliferative disorders1 ) .
in contrast , polyclonal gammopathy represents the diffuse activation of b cells , and is ... | polyclonal gammopathy represents the diffuse activation of b cells and is usually related to inflammation or immune - related diseases .
however , the mechanisms leading to polyclonal gammopathy are essentially speculative .
generally , infectious , inflammatory , or various other reactive processes may be indicate... |
acrylamide ( aa ) was first detected in heat - treated foods , especially potato chips , at high concentrations ( mg / kg ) by a group of swedish researches [ 1 - 3 ] .
this finding aroused great interest in all the world because of the well - known toxicity of aa , classified as " probably carcinogenic to humans " (... | summaryintroduction.acrylamide , produced during thermal processing of carbohydrate - rich foods , is classified as " probably carcinogenic to humans " by the international agency for research on cancer.objective.the aim of this study was to determine acrylamide levels in biscuits and breakfast cereals considering the ... |
pregnant women are at risk of
infection during labor and delivery ; most infections
of the female pelvic
organs occur when normal flora of the female
genital or gastrointestinal tract
contaminate the normally sterile amniotic fluid and uterus .
these bacteria can
become pathogenic , particularly in devita... | background . knowledge , attitudes , and practices of obstetricians and gynecologists regarding the centers for disease control and prevention ( cdc ) recommendations for prevention of healthcare - associated group a streptococcal ( gas ) infections as well as general management of pregnancy - related and postpartum in... |
when various talkers speak concurrently , listeners are required to identify target speech but also to identify location of the target talker for the segregation of competing speech signals . in this everyday listening situation
, binaural hearing has been known to provide better speech perception and sound localizat... | background and objectivesgiven that only a few studies have focused on the bimodal benefits on objective and subjective outcomes and emphasized the importance of individual data , the present study aimed to measure the bimodal benefits on the objective and subjective outcomes for adults with cochlear implant.subjects a... |
there are multiple genetic variants of this enzyme and clinical circumstances that might influence the activity of plasma cholinesterase and eventually lead to prolonged neuromuscular blockade following succinylcholine application .
here , we report a parturient woman with atonic bleeding who suffered significant blo... | summarybackgroundthe muscle - relaxing effects of succinylcholine are terminated via hydrolysis by plasma cholinesterase .
there are multiple genetic variants of this enzyme and clinical circumstances that might influence the activity of plasma cholinesterase and eventually lead to prolonged neuromuscular blockade fo... |
urinary tract infection is one of the commonest bacterial infections encountered in daily clinical practice .
it has been estimated that worldwide about 150 million people suffer from asymptomatic and symptomatic utis each year . in most parts of the sub - saharan africa , as well as in other developing parts of the ... | background . in most hospitals of developing countries ,
urinary tract infections are treated empirically because of lack of culture facilities .
this leads to emergence of multiresistant uropathogens .
culturing and drug susceptibility testing are essential to guide therapy . objectives . to assess changing prev... |
aggressive periodontitis was seen as a specific type of periodontitis in the 1999 international workshop in which microbiological criteria were generally included as elevated proportions of actinobacillus actinomycetemcomitans ( a.a ) and , in some populations , porphyromonas gingivalis ( p.g ) .
it has long been rec... | objective : systemic antibiotics and locally applied antimicrobial agents have been suggested to enhance clinical parameters .
patients exhibiting aggressive periodontitis in particular benefit from adjunctive antibiotic therapy .
the purpose of this investigation was to evaluate the effect of local antibiotic ther... |
total joint replacement by endoprosthesis is a widely used procedure to restore functionality of joints in patients with osteoarthritis .
although surgery is usually safe and successful , complications may arise , particularly due to bacterial infections on and around the implant . according to the literature , the r... | bacterial infections of bones remain a serious complication of endoprosthetic surgery .
these infections are difficult to treat , because many bacterial species form biofilms on implants , which are relatively resistant towards antibiotics .
bacterial biofilms elicit a progressive local inflammatory response , resu... |
in palliative care research and among palliative care providers , a consensus has grown regarding the importance of spirituality .
the need to pay attention to palliative care patients spiritual needs and concerns is generally recognized .
therefore , it is no surprise that in the world health organization ( who ) ... | introduction : there are only a few studies on spirituality among palliative care patients in india .
this gap in research may be caused by the absence of relevant questionnaires and scales specifically designed for indian palliative care populations . in this study
, we describe the development of such a questionn... |
in recent years , studies in embryonic and somatic stem cells have provided basic insight into the molecular and cellular properties of stem cells .
it is recognized that pluripotent stem cells such as embryonic stem cells ( esc ) can replenish differentiated cell types and achieve long - term tissue reconstitution .... | exploiting the properties of stem cells by microrna ( mirna ) profiling offers an attractive approach to identify new regulators of stem cell fate .
although numerous mirna have been screened from hematopoietic stem cells ( hsc ) , the targets corresponding to many of these mirna have not yet been fully elucidated . ... |
development and differentiation are characterized by genetic circuitry or gene regulatory networks ( grns ) that have inherent forward momentum encoded by a number of regulatory motifs ( davidson , 2010 ) . to self - renew and maintain differentiation potential , stem cells must structure their grns so as to arrest or ... | summarywe explore cell heterogeneity during spontaneous and transcription - factor - driven commitment for network inference in hematopoiesis .
since individual genes display discrete off states or a distribution of on levels , we compute and combine pairwise gene associations from binary and continuous components of... |
a 28-year - old female born out of a second - degree consanguineous marriage presented with a gradual onset of decrease in vision in both eyes for 5 years .
the patient was alright till the age of 10 years , when she developed skin changes , failure to gain weight , and had oligomenorrhea and irregular menses .
she... | werner 's syndrome ( ws ) is a rare autosomal recessive disorder with multisystem manifestations of premature aging from the second decade of life .
cataract is one of the features of ws .
cataract surgery is complicated with postoperative wound dehiscence and bullous keratopathy when the surgery is done by intraca... |
researchers have recently developed neuroimaging technologies that provide us with powerful tools to better understand the complexity of human brain
behavior relationships with the goal of discovering and developing novel , safe , effective and personalized therapeutics to treat brain disorders . recognizing the pote... | while reducing the burden of brain disorders remains a top priority of organizations like the world health organization and national institutes of health , the development of novel , safe and effective treatments for brain disorders has been slow . in this paper , we describe the state of the science for an emerging te... |
colorectal cancer ( crc ) is the fourth leading cause of cancer - specific mortality worldwide , with 610,000 related deaths each year1 .
crc is the fourth most common form of cancer in the united states2 and the third leading cause of cancer - related death in the western world3 .
laparoscopic resection for crc wa... | purpose : we conducted a meta - analysis to evaluate and compare the short- and long - term results of laparoscopic colorectal surgery ( lcrs ) and conventional open surgery ( ocrs ) for colorectal cancer ( crc).methods : we searched relevant papers published between january 1990 and may 2011 .
we analyzed the outcom... |
lumbar instability is a common symptom and also one of the causes of low back pain .
the definition of lumbar segmental
instability is decreased stiffness of the spinal motion segments2 .
previous studies have indicated that lumbar instability is
associated with pain possibly3 ; and it may
be due to a defect ... | [ purpose ] the purpose of this study was to investigate the effects of 6 weeks sling
exercise training for clients with low back pain on the levels of pain , disability ,
muscular strength and endurance .
[ subjects and methods ] twelve chronic lbp subjects
participated in this study .
subjects were randomly... |
the inhalational anaesthetic agents presently available are metabolised only to a small extent and are largely exhaled unchanged .
this property can be taken advantage of , to perform successful , economic and safe low flow anaesthesia ( lfa ) .
the aim of our survey was to get data on the current practice of lfa... | background and aims : with the availability of modern workstations and heightened awareness on the environmental effects of waste anaesthesia gases , anaesthesiologists worldwide are practicing low flow anaesthesia ( lfa ) .
although lfa is being practiced in india , hard evidence on the current practice of the same ... |
alzheimer s disease ( ad ) and related dementias cause impairment in functional abilities , including ability to drive .
over half a million individuals in canada have a diagnosis of ad , and in nova scotia , approximately 5,400 individuals with a diagnosis of ad continue to drive . following a diagnosis of ad , almo... | background and purposeover half a million canadians have a diagnosis of dementia , approximately 2530% of whom continue to drive .
individuals with dementia have a risk of motor vehicle collision up to eight times that of drivers without dementia . in nova scotia ,
the responsibility of reporting unsafe drivers is ... |
brca1 and brca2 are the most well known gene mutations responsible for an increased risk for developing breast cancer .
a brca1 or brca2 mutation carrier ( brca - mc ) has approximately a 3% risk of getting breast cancer before the age of 30 .
this risk increases to almost 50% when she reaches the age of 50 and bec... | the appearance of malignant lesions in brca1 and brca2 mutation carriers ( brca - mcs ) on mammography and magnetic resonance imaging ( mri ) was evaluated .
thus , 29 brca - mcs with breast cancer were retrospectively evaluated and the results compared with an age , tumor size and tumor type matched control group of... |
assuming that psychological status affects all medical conditions , researchers have focused on these psychological status ' roles especially on noncommunicable disease with almost unknown origin . the relationship of depression , anxiety , and psychological distress with chronic metabolic disease such as diabetes mell... | objective .
current study was designed to investigate the association of metabolic syndrome ( mets ) with depression , anxiety , psychological distress , and quality of life ( qol ) .
design .
two hundred and fifteen contributors with mets and 253 participants without mets were randomly selected from 2151 partici... |
increased intraspinal pressure exerted by an expanding mass such as a slow - growing intraspinal tumor is a common cause of erosion ( scalloping ) of the posterior vertebral wall [ 18 ] . as for other causes of scalloping , communicating hydrocephalus , marfan syndrome ,
ehlers danlos syndrome , ankylosing spondylit... | erosion of spinal osseous structure , so - called scalloping , has been rarely reported associated with herniated nucleus pulposus ( hnp ) .
we report a rare case of hnp causing erosion of the spinal osseous structure ( including lamina ) .
the patient was an 81-year - old woman with 3-year history of low - back pa... |
an 80-year - old woman presented to the emergency department complaining that she had defecated a 40-cm corded piece of dark - red tissue , without severe symptoms , after taking laxatives .
laboratory data revealed a white blood cell count of 7.8 10 and a hematocrit of 31.9% .
the rest of the laboratory test resu... | colon cast passage , which is the spontaneous passage of a full - thickness , infarcted colonic segment per rectum , is a rare occurrence .
the main cause is acute ischemic colitis resulting from a circulation compromise .
most of the colon cast cases reported were secondary to abdominal aortic aneurysm repairs or ... |
when treating pulmonary cancer complicated by interstitial pneumonia , it is critical to determine whether or not surgery is indicated .
furthermore , the greatest problem when considering treatment for pulmonary cancer complicated by interstitial pneumonia is acute exacerbation , which presents an added risk in case... | highlightsit is difficult to determine whether surgery is indicated in patients with lung cancer with multiple nodular shadows in multiple lung lobes.physicians are reluctant to perform surgery for patients with lung cancer and interstitial pneumonia.however , surgery is the only treatment method that is expected to ac... |
the global program to eliminate lymphatic filariasis ( gpelf ) currently implements two diagnostic tools : detection of microfilariae ( mf ) and the detection of circulating filarial antigen ( cfa ) .
both tools have proven to be extremely useful during the elimination program stages , where parasite prevalence is re... | demonstration of successful elimination of lymphatic filariasis ( lf ) in endemic countries requires sensitive diagnostics for accurate definitions of endpoints and future surveillance .
there has been interest in complementing available diagnostics with antibody serology testing in children , since negative serology... |
rapid detection and identification of infectious pathogens in clinical samples is very challenging , but it is essential to guide the therapy and predict the outcome .
traditional clinical microbial diagnostic methods like physiology and biochemical identification , serological tests , and automated detection technol... | background : the dilemma of pathogens identification in patients with unidentified clinical symptoms such as fever of unknown origin exists , which not only poses a challenge to both the diagnostic and therapeutic process by itself , but also to expert physicians.methods:in this report , we have attempted to increase t... |
anterior chamber ( ac ) aqueous tube shunt surgery improves intraocular pressure ( iop ) control in glaucoma patients .
initially used as a treatment for refractory glaucoma , its use is now more widespread [ 13 ] .
one of the possible complications of tube shunt surgery , however , is corneal endothelial cell loss... | purpose .
this cross - sectional , observational study used fourier - domain optical coherence tomography ( oct ) to examine the position , patency , and the interior entrance site of anterior chamber ( ac ) aqueous tube shunts . methods .
the oct , slitlamp biomicroscopy , and gonioscopy findings of 23 eyes of 18 ... |
renal transplantation is regarded as the optimal treatment for patients with end - stage renal disease . however , as long - term graft survival is still limited , most transplant patients will face graft loss after 9 - 10 years .
these patients are generally more fragile and in considerable need of new grafts , in c... | it has been reported that kidney retransplant patients had high rates of early acute rejection due to previous sensitization .
in addition to the acute antibody - mediated rejection ( abmr ) that has received widespread attention , the early acute t - cell - mediated rejection ( tcmr ) may be another important issue ... |
polymerase chain reaction ( pcr ) based cloning of gene of interest with high gc content is a long recognized problem .
pcr is a most sensitive tool and various factors have to be optimized for amplification of gene of interest .
high gc content of the gene generates complication during primer designing like mismat... | the genome of mycobacterium is rich in gc content and poses problem in amplification of some genes , especially those rich in the gc content in terminal regions , by standard / routine pcr procedures .
attempts have been made to amplify three gc rich genes of mycobacterium sp .
( rv0519c and rv0774c from m. tubercu... |
healthy horses : eleven foals ( 7 males and 4 females under one year old )
and an yearling female thoroughbred were used for evaluation of the development stages of
the gastric mucosae of healthy horses .
details of the program for endoscopic examination are
summarized in table 1table 1.endoscopic examination o... | to contribute to early diagnosis and treatment of gastric ulcer of foals , we examined the
gastric mucosa of healthy and affected foals using an endoscope . in healthy foals ,
the
characteristic changes in the development of the squamous mucosa were seen mainly in the
squamous mucosa , and maturation of the squ... |
micrornas ( mirnas ) are small non - coding rnas ( 2123 nt in length ) that post - transcriptionally regulate gene expression by blocking translation or inducing degradation of the targeted mrna ( 1 ) . since their first identification in caenorhabditis elegans in 1993 ( 2 )
, the number of annotated mirnas and mirna... | micrornas ( mirnas ) are small endogenous rna molecules that regulate gene expression through mrna degradation and/or translation repression , affecting many biological processes .
diana - microt web server ( http://www.microrna.gr/webserver ) is dedicated to mirna target prediction / functional analysis , and it is ... |
recent estimates indicate that nearly 17.2% of americans aged older than 40 years have a cataract in either eye , and this percentage is expected to rise to about 50% in the next 10 years.1 according to national eye institute estimates , more than 50% of americans have a cataract or have undergone cataract surgery by t... | backgroundthe purpose of this study was to evaluate the safety and tolerability of besifloxacin ophthalmic suspension 0.6% compared with moxifloxacin ophthalmic solution 0.5% , when used for infection prophylaxis following uncomplicated phacoemulsification clear cornea surgery using sutureless corneal incision.methodst... |
pythiosis is a chronic granulomatous disease caused by the oomycete pythium insidiosum belonging to the kingdom stramenopila
.
these opportunistic pathogens live in warm stagnant water and are most often reported in regions with tropical and subtropical environments . in brazil ,
the disease occurs predominantly ... | this study reports the epidemiological , pathological and mycological findings of cutaneous pythiosis in cattle in southern brazil .
23 calves , that were kept next to a river with extensive marshy regions , presented ulcerated cutaneous lesions in thoracic and pelvic limbs , sometimes extending to the ventral thorac... |
diatoms are globally distributed , eukaryotic brown microalgae that participate in various biogeochemical cycles and play key roles in maintaining the ecological balance of the earth .
they are major contributors to global primary production and co2 sequestration ( 1,2 ) , and are also receiving attention as a potent... | the diatom expressed sequence tag ( est ) database was constructed to provide integral access to ests from these ecologically and evolutionarily interesting microalgae .
it has now been updated with 130 000 phaeodactylum tricornutum ests from 16 cdna libraries and 77 000 thalassiosira pseudonana ests from seven libra... |
the mucous membrane that covers the digestive and urogenital tracts , the respiratory canal , the eye conjunctiva , the inner ear , and layers of most of the exocrine glands , is a strong component of the immune system , with very specialized mechanical and chemical barriers that either prevent the entry of foreign bod... | the body defense mechanism has evolved to protect animals from invading pathogenic microorganisms and cancer .
it is able to generate a diverse variety of cells and molecules capable of specifically recognizing and eliminating a limitless variety of foreign invaders .
these cells and molecules act together in a dyn... |
in the field of anesthesia postoperative pain management is an important and challenging matter , and at present , as optimal for diminishing postoperative pain , there is no method of preemptive analgesia accepted . for the management of postoperative pain ,
different methods have been assessed in many studies . in ... | background : this double - blinded , randomized clinical trial was designed to evaluate the comparison of intravenous versus intraarticular ( ia ) administration of midazolam on postoperative pain after knee arthroscopy.materials and methods : in this study , 75 patients randomized in three groups to receive 75 mc / kg... |
the use of dual antiplatelet therapy ( dapt ) with aspirin and p2y12 receptor inhibitors is recommended by current clinical guidelines for at least 12 months in patients with acute coronary syndrome ( acs ) or percutaneous coronary intervention ( pci ) . , proton pump inhibitors ( ppis )
, during the past few years ,... | backgroundthere is great debate on the possible adverse interaction between proton pump inhibitors ( ppis ) and clopidogrel . in addition , whether the use of ppis affects the clinical efficacy of ticagrelor remains less known .
we aimed to determine the impact of concomitant administration of ppis and clopidogrel or... |
data , clinical data in particular , is essential to create clinically relevant information in healthcare for treatment s diagnosis and prognosis besides other concerns , such as the information of potential conflicting treatments or contraindication drugs . as technology advances ,
new ways of acquiring and processi... | clinical data are crucial for any medical case to study and understand a patient s condition and to give the patient the best possible treatment .
pervasive healthcare systems apply information and communication technology to enable the usage of ubiquitous clinical data by authorized medical persons . however , quali... |
a 52-year - old male had been treated for chronic renal failure and had been on continuous ambulatory peritoneal dialysis for 9 years .
abdominopelvic computed tomography ( ct ) revealed a round mass in the lower pole of the left kidney and marked hydronephroureter with cortical thinning of bilateral kidneys ( fig . ... | we report a rare case of oncocytic renal cell carcinoma ( rcc ) with tubulopapillary growth in the background of tuberculous end - stage kidney disease .
histology of the renal mass consisted of oncocytic cells forming solid , thin tubules and rare papillae .
the tumor had abundant eosinophilic oncocytic cells cont... |
autosomal recessive distal renal tubular acidosis ( drta ) is usually a severe disease of childhood , which most often presents as failure to thrive in infancy or systemic upset , with vomiting and/or dehydration in the context of intercurrent illness .
the fundamental defect in drta is an inability of the kidneys to... | autosomal recessive distal renal tubular acidosis is usually a severe disease of childhood , often presenting as failure to thrive in infancy .
it is often , but not always , accompanied by sensorineural hearing loss , the clinical severity and age of onset of which may be different from the other clinical features .... |
a pilot expanded newborn screening programme to detect inherited metabolic disorders by means of liquid chromatography coupled with tandem mass spectrometry ( lc - ms / ms ) began in the campania region , southern italy , in 2007 . by october 2009 , > 8,800 dried blood samples on filter paper from 11 hospitals in the r... | a pilot expanded newborn screening programme to detect inherited metabolic disorders by means of liquid chromatography coupled with tandem mass spectrometry ( lc - ms / ms ) began in the campania region , southern italy , in 2007 . by october 2009 , > 8,800 dried blood samples on filter paper from 11 hospitals had been... |
in the food industry , sucrose is the most commonly used sweetener as a result of its physical and chemical and sensory characteristics . however , because of its high caloric value and cariogenic properties , alternative sweeteners are being studied . in the past two decades , there has been an increasingly high inter... | isomaltulose is a noncariogenic reducing disaccharide and also a structural isomer of sucrose and is used by the food industry as a sucrose replacement .
it is obtained through enzymatic conversion of microbial sucrose isomerase .
an erwinia sp .
d12 strain is capable of converting sucrose into isomaltulose .
t... |
the current standard red blood cell ( rbc ) storage time of up to 42 days is not based upon a demonstrable therapeutic benefit , but instead on the observed return of 70% of the viable transfused rbcs at 24 hours after storage for 42 days or less .
the structural , biochemical and immunological changes that rbcs unde... | since the inception of blood banking , refinements in laboratory processes have allowed for progressively longer storage times of red blood cells . whilst advantageous for the logistics of stock management , the clinical impact of the duration of red blood cell storage prior to transfusion remains uncertain , and a top... |
the wt1 gene , located on chromosome 11p13 , plays a crucial role in kidney and genital system development .
recent studies have demonstrated that mutations in wt1 , leading to frasier syndrome and denys - drash syndrome ( dds ) , can also cause isolated steroid - resistant nephrotic syndrome ( isrns ) .
incomplete... | mutations in the wt1 gene , leading to denys - drash syndrome and frasier syndrome , can also cause isolated steroid - resistant nephrotic syndrome ( isrns ) .
previous studies have reported six pairs of monozygotic twins with wt1 mutations , including one presenting with discordant phenotypes with identical wt1 muta... |
moraxella osloensis , an oxidase - positive , nonmotile , asaccharolytic , aerobic gram - negative coccobacilli is a part of the normal flora of the human respiratory tract ( 1 , 2 ) . the organism is difficult to identify because of presence of several other species with similar phenotypic characteristics .
species ... | we had three cases of moraxella osloensis meningitis .
the species identification was impossible by conventional and commercial phenotypic tests .
however , we could identify the species using the 16s rrna gene sequencing .
determination of clinical significance was difficult in one patient .
all three patients... |
the institute of medicine ( iom ) has fruitfully distinguished between health care difference ( in which race / ethnicity groups have divergent absolute values of health care access or outcomes ) and disparity ( the difference remaining after other potentially mediating factors have been statistically , or otherwise ... | this study analyzed virginia data from the most recent national survey of children with special health care needs .
logistic regression models were run for six maternal and child health bureau core outcomes and included demographics , child characteristics , health care providers , and health care access variables as... |
picture archiving and communication systems ( pacs ) and other imaging - related information technology ( it ) systems have grown in popularity over the last decade . initially used within departments as radiology - focused tools with a small number of users , these systems have now grown to become enterprise - class r... | the goal of all radiology information technology ( it ) support organizations is excellent customer service through the availability of critical clinical information services , such as picture archiving communication systems and radiology information systems . despite these goals ,
it support personnel often act like... |
endovascular treatment of aortic pathologies has become the predominant form of repair.1 ) standard endovascular repair of aortic pathologies , in which the internal iliac artery is generally embolized , can lead to complications , such as buttock claudication , colon ischemia , and erectile dysfunction.2 ) therefore ,... | standard endovascular repair of iliac / aortoiliac pathologies can lead to complications , such as buttock claudication , colon ischemia and erectile dysfunction .
branch grafts have been developed but require at least 6 weeks for customization and are not currently available in china ; they are also quite expensive ... |
diabetes mellitus ( dm ) is a systemic disease with several major complications affecting both the quality and length of life .
the chronic gram - negative infection of periodontal origin may be considered a potential focus of infection that aggravates metabolic control in patients who have diabetes .
the multifact... | background : the aim of this study was to determine if glycosylated hemoglobin is elevated in patients with chronic periodontitis who have not been diagnosed with diabetes and also to compare the hba1c levels that were obtained with lab and chairside test kit.materials and methods : a case control study was designed
... |
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