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of all the problems that fall into the dentofacial deformity category , mandibular deficiency is the most prevalent that is usually treated with functional appliance in a preadolescent child and with orthognathic surgery or distraction osteogenesis in adults . as a general guideline , even in the most favorable circums...
background : the aim of this study was to evaluate the effect of local injection of human growth hormone ( gh ) in stimulating cartilage and bone formation in a rabbit model of temporomandibular joint ( tmj).materials and methods : in an experimental animal study , 16 male albino new zealand white rabbits aged 12 weeks...
we studied 21 men and 12 women with type 2 diabetes attending the outpatient diabetes clinic of laiko general hospital . current smokers , subjects aged > 70 years , and those with clinically apparent macrovascular disease , renal impairment or microalbuminuria , a1c > 8.5% , and fasting triglycerides > 300 mg / dl w...
objective to examine the acute effects of consumption of monounsaturated ( mufas ) and saturated fatty acids ( safas ) on endothelial function in subjects with type 2 diabetes.research design and methods a total of 33 participants were examined after consumption of two different isocaloric meals : one rich in mufa an...
let f , be the model associated to the univariate gaussian time series { yt ; t } that is stationary or nonstationary but with stationary backward differences of order d , and let { yt , t = 1 , , we propose a new estimation method for the parameter 's vector that is based on the matching between the empirica...
this article presents a new estimation method for the parameters of a time series model . we consider here composite gaussian processes that are the sum of independent gaussian processes which , in turn , explain an important aspect of the time series , as is the case in engineering and natural sciences . the propo...
human papillomavirus ( hpv ) infection is the most frequent sexually transmitted disease in the united states . the major clinical focus in women with hpv has been on the prevention of cervical cancer , predominantly associated with oncogenic hpv types such as 16 and 18 , through screening , and , more recently , thr...
objective . to evaluate if new imiquimod formulations using a shorter treatment duration are safe and efficacious to treat anogenital warts . methods . in two studies 534 women 12 years of age ( mean 33.4 ) with 230 warts ( mean 7.9 ) and total wart area 10 mm2 ( mean 166.3 ) were randomized ( 1 : 2 : 2 ) to ...
the nutrition therapy recommended for people with diabetes is often based on theories or the opinions of the medical treatment provider . people with diabetes often find this frustrating or confusing , because they hear or read that ideally they should be on a low - carbohydrate diet but from other sources they are t...
current nutrition therapy recommendations for the prevention and treatment of diabetes are based on a systematic review of evidence and answer important nutrition care questions . first , is diabetes nutrition therapy effective ? clinical trials as well as systematic and cochrane reviews report a ~1%2% lowering of he...
vasospastic disorders ( vd ) are common , with a prevalence of 3.3% to 22% in the general population . if there is an underlying etiologic systematic disorder , it is called secondary form , which is uncommon . the other form of this disorder , without any underlying etiologic factors , most vasospastic disorder di...
backgroundvasospastic disorders are common worldwide . in daily practice , routine blood samples are used for several investigations . in this study we aimed to determine the possible correlations between lymphocyte count , platelet indices , and the severity of vasospastic disorders.material/methodsdata of 102 patie...
yttrium-90 radioembolization is an effective technique for treatment of primary and secondary liver tumors [ 18 ] . a feared complication of the procedure is nontarget embolization of the radiopharmaceutical , which can result in severe damage to the stomach , duodenum , or pancreas . nontarget embolization to the ...
purposeto evaluate the safety and efficacy of two different methods of proximal cystic artery embolization in patients undergoing yttrium-90 radioembolization.materials and methodsforty - six patients had cystic artery embolization performed immediately before yttrium-90 radioembolization , either by using gelfoam pled...
targeted , noninvasive neuromodulation of the brain of an otherwise awake subject could revolutionize both basic and clinical neuroscience . toward this goal , we have developed nanoparticles that allow noninvasive uncaging of a neuromodulatory drug , in this case the small molecule anesthetic propofol , upon...
sodium valproate is a broad - spectrum antiepileptic that has proven efficacy against all seizure types , which makes it a useful antiepileptic when the exact seizure classification is unknown or multiple seizure - types exists . the aromatic antiepileptics , namely , phenytoin , carbamazepine , phenobarbitone , and ...
a case of stevens - johnson syndrome following treatment with sodium valproate is presented here . a 20-year - old male was put on sodium valproate monotherapy for the migraine , with generalized epilepsy . he developed vesicles and bullae in the oral and nasal mucosa with conjunctivitis , after 10 days of treatmen...
thanks to the advances in therapy and improvements in public heath policies , many of us are now living longer and better . however , the final stage of our lives has also become more heterogeneous and complicated , pending on the different clinical scenarios . figure 1 shows the four potential clinical courses amo...
as medical science continues to advance , patients nowadays with progressive cardiopulmonary diseases live to older ages . however , they too will eventually reach their unsustainable physiological limit and many die in poor health and discomfort prior to their demise . regrettably many physicians have not kept pac...
in permanent i-125 seed implants of the prostate , the quality of the implant depends , amongst other factors , on the quality of the image modality used during implantation . the image modality most frequently used in the operation room ( or ) is transrectal ultrasound ( trus ) , although other modalities like compu...
purposeto investigate whether a longer sagittal view and less movement using a dual sagittal crystal probe ( dscp ) for trans rectal ultra sound ( trus ) allow for more accurate online - planning in i-125 permanent implant brachytherapy of the prostate , compared to a single sagittal crystal probe ( sscp).material and ...
in 1968 , wiltse et al.20 ) first described paraspinal sacrospinalis muscle - splitting approach to lumbar spine . this approach decreased bleeding and provided more direct access to the transverse processes and pedicles . mini - transforaminal lumbar interbody fusion ( mini - tlif ) is a powerful minimally invasive ...
objectivemini - transforaminal lumbar interbody fusion ( mini - tlif ) and other minimally invasive approaches introduced for the purpose of treating lumbar degenerative disc disease and instability are achieving high success and safety rates as the conventional approaches . moreover , it has less soft tissue damage ...
arthritis is a complex disorder that comprises more than hundred distinct conditions involving damage to the joints of the body . these include cartilage - degrading enzymes , cytokines , leukotrienes ( lts ) , and prostaglandins ( pgs ) . lts and pgs are produced by the activity of three enzymes5-lipoxygenase , cy...
in the clinical management of arthritis , the choice of nonsteroidal anti inflammatory drug ( nsaid ) remains confusing and controversial . a common practice on the choice of nsaid in clinical management of arthritis is the risk benefit ratio . the main objective of this review is to addresses the main arguments for ...
landiolol is an intravenous short - acting beta - adrenoreceptor blocker , and its wide use is exhibited by rapid wash out and a less - sustained effect on cardiac function after decreasing the dose or stopping its administration . we present a patient with drug - resistant and persistent inappropriate sinus tachycar...
a 20-year - old woman underwent an electrophysiological study for drug - resistant persistent inappropriate sinus tachycardia ( ist ) . use of a high - dose continuous intravenous administration of landiolol , a short - acting beta - adrenoreceptor blocker , made the patients heart rate suddenly drop with a slight ch...
retroperitoneal liposarcomas represent a rare subtype of soft tissue sarcoma because of their localization ( only 20% of soft tissue sarcomas are located retroperitoneally ) and histological type ( only 15% of soft tissue sarcomas are liposarcomas and , of these , only a third develop from perirenal fat ) [ 1 , 2 ] . t...
liposarcomas are neoplasms of mesodermic origin , are derived from adipose tissue and represent < 1% of all malignant tumours . primary liposarcomas of the kidney are very rare . here , we present the cases of two patients diagnosed with retroperitoneal perirenal myxoid liposarcoma . the patients were diagnosed v...
a 64-year - old , 164 cm , 70 kg woman had a five - year history of hypertension and diabetes mellitus . she experienced insomnia , nausea , visual hallucination and left - side tingling sensation 4 months ago and memory impairment and gait disturbance became evident clinically 2 months ago . at that time , she under...
creutzfeldt - jakob disease ( cjd ) is a fatal neurodegenerative disorder in which accumulation of the pathogenic prion protein induces neuronal damage and results in distinct pathologic features . this abnormal prion is an infectious protein and resistant to methods of sterilization currently being used . therefor...
the quality of outcome must be worth the pain of survival. burn care has progressed greatly over the past 70 years . many advances were related to episodes of conflict , with significant progress in the quality of burn care seen during the second world war . the introduction of appropriate first aid ensured ...
with the threat of terrorist activity ever present since the incidents in bali and jakarta , the australian health system must be prepared to manage another mass burn casualty disaster . the australian and new zealand burns association ( anzba ) highlighted the lack of a national burn disaster response before the 200...
von hippel lindau ( vhl ) disease is an autosomal dominant disorder that is characterized by multisystem predilection to develop tumors and cysts.13 the most common tumors manifested include retinal and central nervous system hemangioblastomas , renal cell carcinoma , pheochromocytoma , and pancreatic cystadenoma.1,2 ...
a 7-year - old girl presented with decreased vision in both eyes for 1 month . examination showed visual acuity of 20/50 and 20/60 , no afferent pupillary defect , cecocentral scotomas , and bilateral optic disc edema with extensive peripapillary and macular exudates . magnetic resonance imaging showed multiple cor...
in the new approach , all health care providers have been obligated to maintain and improve the quality and have been accountable for it . that is why different countries have used various methods and tools for the improvement of health care quality to date , but their implementation has always proved challenging . ...
introduction : in the new approach , all health care providers have been obligated to maintain and improve the quality and have been accountable for it . one of the ways is the implementation of clinical governance ( cg ) . more accurate understanding of its challenges can help to improve its performance.aims:in th...
with the changes in the international code of nomenclature for algae , fungi , and plants ( icn ; mcneill et al . 2012 ) , one species of fungus may no longer be referred to by more than one scientific name . the practice of giving separate scientific names to sexual and asexual morphs ( dual nomenclature ) of the ...
following the change that eliminated dual naming of sexual and asexual morphs of fungi , generic names of pezizomycetes have been evaluated to determine which of the competing names should be recommended for use . evaluation is based on congruence of type species to determine if the names are congeneric and which nam...
aqueous humor is secreted by the ciliary process to the posterior chamber and goes through the pupil to the anterior chamber ( inflow ) . it then leaves the anterior chamber through the trabecular meshwork to the venous system ( outflow ) . normally , there is equilibrium between inflow and outflow that creates nor...
objectivewe aimed to compare intraocular pressure ( iop ) measurements via three different tonometers : the goldmann applanation tonometer ( gat ) , the tono - pen xl ( tpxl ) , and a non - contact airpuff tonometer ( nct).methodsthis was a cross - sectional study of 200 eyes from 200 patients . right eyes of all pat...
cardiovascular disease is a major and growing cause of morbidity , mortality , and disability worldwide . atherosclerosis , a chronic low - grade inflammatory condition , is the underlying cause of most heart attacks and strokes . the atherosclerotic process , which begins early and progresses over the life course ...
chronic exposure to urban traffic pollution is documented to promote atherosclerosis in adults but little is known about its potential effects in children . our study examined the association of long - term exposure to traffic with carotid intima - media thickness ( cimt ) in 287 healthy children . residential prox...
meatus was normal in 3 , hypospadiac in 2 , and epispadiac in one patient . the most common associated anomaly was bifid scrotum ( 5 cases ) , and other common anomalies consisted of bladder duplication ( 3 cases ) , imperforate anus ( 2 cases ) , and hypospadias ( 2 cases ) . phalloplasty was performed for all bu...
backgrounddiphallus is an extremely rare anomaly . numerous associated genitourinary , gastrointestinal and other anomalies have been described with diphallus . these patients need several investigations , and finally surgical intervention.cases presentationin this report we discuss six patients with diphallus whic...
fibrosis is an inappropriate tissue repair of the liver resulting from almost all of the chronic liver injuries including alcohol induced damage , chronic viral hepatitis ( hbv and hcv ) , autoimmune , parasitic , and metabolic diseases , and less frequently toxic or drugs exposure . in contrast with the traditional ...
inflammation is a central feature of liver fibrosis as suggested by its role in the activation of hepatic stellate cells leading to extracellular matrix deposition . during liver injury , inflammatory cells are recruited in the injurious site through chemokines attraction . thus , inflammation could be a target to ...
signature genes are genes that are unique to a certain taxonomic clade , and are common throughout all its major subclades . the plausible evolutionary explanation for such a phylogenetic distribution is that the gene was invented in the ancestral lineage , and constituted an important innovation that possibly allowe...
signature genes are genes that are unique to a taxonomic clade and are common within it . they contain a wealth of information about clade - specific processes and hold a strong evolutionary signal that can be used to phylogenetically characterize a set of sequences , such as a metagenomics sample . as signature gene...
the saphenous vein and various arterial grafts have been used and evaluated for their functional efficacy ; however , the choice of conduit has been a major concern for cardiac surgeons desiring a good surgical outcome . it is clear that the internal thoracic artery ( ita ) is superior to the saphenous vein in terms ...
throughout its 30-year history , the right gastroepiploic artery ( gea ) has been useful for in situ grafts in coronary artery bypass grafting ( cabg ) . the early graft patency rate is high , and the late patency rate has improved by using the skeletonized gea graft and proper target selection , which involves havin...
transthoracic echocardiography has high sensitivity to detect secundum - type atrial septal defects(asds ) and up to 100% for defects of the interatrial foramen primum , while its diagnostic usefulness for more uncommon causes of shunting at the atrial level is considerably less . in particular , diagnostic images of...
in contrast with transthoracic echocardiography , transesophageal echocardiography provides a sure way to make the diagnosis of sinus venosus atrial septal defect ; on the other hand this abnormality is more complex than that seen with the secundum atrial septal defect , and inexperienced operators may fail to recogniz...
haemophilia is a congenital bleeding disorder linked to the x chromosome of the human genome , represented mainly by two types : haemophilia a deficiency of factor viii ( most frequent ) and haemophilia b deficiency of factor ix . joint bleeding associated with muscle bleeding represents 90% of bleeding episodes in...
the penetration of beta energy of 153-samarium ( 153sm ) ( 0.8 mev ) is not only appropriate for synovectomy of median articulations but is possible to improve the radiobiological effect using increased activities . the aim of this study was to assess the effectiveness of 185 mbq and 740 mbq of 153-samarium hydrox...
in response to environmental factors , bacteria have been developing small molecule resistance strategies for millions of years . recently , drug resistance reached pandemic status while antibiotic development has slowed substantially . penicillins , the first antibiotics , and cephalosporins ( -lactams ) ...
benzylpenicillin , a member of the -lactam antibiotic class , has been widely used to combat bacterial infections since 1947 . the general mechanism is well - known : a serine protease enzyme ( i.e. , dd - peptidase ) forms a long lasting intermediate with the lactam ring of the antibiotic known as acylation ...
the dorsal surface of tongue contains numerous macroscopic papillae . these papillae differ somewhat in shape , are named according to their morphologic characteristics , and serve either a mechanical or a gustatory function ( davies et al . , 1979 ; boshell et al . , 1982 ; chamorro et al . , 1986 ; holland et...
abstractthe purpose of the present study was to investigate the morphological characteristics of the developing vallate papillae ( vp ) of korean native goats using scanning electron microscopy . in prenatal development of the vp , primordia of the vp were observed and the moat was shallowly spread in 60-day - ol...
prolidase ( pr ) is a cytosolic enzyme , which hydrolyzes the peptide bonding of imidodipeptides and imidotripeptides , which include proline or hydroxyproline in the carboxyl terminal position [ 13 ] . this enzyme is present in many tissues in animals and humans and plays an important role in collagen metabolism . ...
backgroundthe aim of this study was to determine prolidase activity in conjunctival tissue and its relationship with pterygium.material/methodsprolidase activity was measured in 23 pterygium and 25 healthy conjunctival tissues and the 2 groups were compared.resultsprolidase enzyme activity could not be measured in eith...
the sinking skin flap syndrome ( ssfs ) is a rare complication that occurs in patients with large cranial defects following a decompressive craniectomy ( dc).2 ) a known cause is local in - folding of the scalp or scarring at the craniectomy site between the overlying skin and dura , which exerts direct pressure on the...
the sinking skin flap syndrome ( ssfs ) is a rare complication after a large craniectomy . hemorrhage infarction after a cranioplasty is a very rare complication with only 4 cases to date . we report a case of the patient who underwent an autologous cranioplasty to treat ssfs that developed intracerebral hemorrhage...
hearing is the main source for speech and language skill acquisition in children with normal hearing ability . hearing loss can cause delay in these skills , making the communication process more difficult . in infants , it is recommended that a complete hearing evaluation be performed with electrophysiological and...
summary introduction : the use of conventional tympanometry is not sufficiently sensitive to detect all cases of middle ear changes , and this hinders accurate diagnosis . objective : to characterize acoustic immittance measures of infants from 0 to 3 months of age using multifrequency tympanometry in a prospecti...
genomic disorders are diseases that result from rearrangements of the human genome rather than from dna sequence base changes . moreover , such rearrangements occur because of architectural features of the genome that incite genome instability . the idea of genomic disorders emanated from locus - specific studies o...
it is now becoming generally accepted that a significant amount of human genetic variation is due to structural changes of the genome rather than to base - pair changes in the dna . as for base - pair changes , knowledge of gene and genome function has been informed by structural alterations that convey clinical phenot...
gonococcal infection has been recognized by different human societies as a distinct disease for over 4,000 years ( handsfield and sparling , 2005 ) . gonorrhea , the infection caused by the neisseria gonorrhoeae , is the second most commonly reported notifiable disease in the united states today with 355,991 cases of...
neisseria gonorrhoeae has been shown to form biofilms during cervical infection . thus , biofilm formation may play an important role in the infection of women . the ability of n. gonorrhoeae to form membrane blebs is crucial to biofilm formation . blebs contain dna and outer membrane structures , which have been...
with a view to the preservation of dental , periodontal , articular , and muscular health , it is important to observe adequate static and functional occlusion . in static occlusion , simultaneous , bilateral , and homogeneous contacts should be observed between the maxillary and mandibular teeth ; absence of rotatio...
objectives evaluate the thickness and the marking quality of different occlusal contact registration strips ( ocrs ) and a possible correlation between them.material and methods the following ocrs were selected : accufilm ii , bk20 , bk21 , bk22 , bk23 , bk28 , and bk31 . the thickness was measured in three points of...
human plasma samples from symptomatic and asymptomatic individuals - human plasma samples were obtained during an epidemiological survey from persons living in the surroundings of porto velho , the capital of the state of rondnia ( ro ) ( brazil ) . ethical clearance was obtained from the ethical board of the ins...
in the amazon region , there is a virtual absence of severe malaria and few fatal cases of naturally occurring plasmodium falciparum infections ; this presents an intriguing and underexplored area of research . in addition to the rapid access of infected persons to effective treatment , one cause of this ph...
liver , the largest organ in the body , is being evolved to maintain the body 's internal milieu and also protects itself from the challenges it faces during its functioning . it plays an important role in the metabolism , and storage of drugs ; therefore it is susceptible to a high degree of toxicity . when admini...
background : liver is the main organ for metabolism of drugs and hepatotoxicity is a potential adverse effect for most drugs.aims:this study was to study the frequency of drug - induced hepatotoxicity and to find the common drugs causing hepatotoxicity.materials and methods : the study was conducted at a tertiary care ...
+ + epidemiologic studies have focused attention on the health effects of fine particulate air pollutants < 2.5 microm in diameter ( pm2.5 ) . to further characterize the potential effects of fine particles , we investigated the relationship of air pollution to mortality in mexico city during 1993 - 1995 . the conc...
even so , bipolar dislocation of the clavicle is an unusual injury and seldom reported in the literature . conservative management is used for almost all the cases and only selected cases will undergo surgical treatment . a 52 year old right electrician presented to the emergency department following a fall from a ...
introduction : shoulder injuries after high velocity trauma are common . clavicle is affected in almost half of these cases . even so , bipolar dislocation of the clavicle is an unusual injury and seldom reported in the literature . conservative management is used for almost all the cases and only selected cases ...
there are no previous published studies on the incidence , course and prognosis of midback pain ( mbp ) after traffic collisions . there are no previous published studies on the incidence , course and prognosis of midback pain ( mbp ) after traffic collisions . midback pain is a common complaint among those with tr...
abstractbackgroundtraffic collisions often result in a wide range of symptoms included in the umbrella term whiplashassociated disorders . midback pain ( mbp ) is one of these symptoms . the incidence and prognosis of different traffic injuries and their related conditions ( e.g. neck pain , low back pain , depress...
many studies have shown that the strength decreases after age 60 ( 1 , 2).with increasing age , the muscle becomes weak due to several reasons ; decrease in the muscle fiber size , decrease in number of type ii fiber , and reduction in the number of motor units and also a reduction in the ability to activate motor unit...
background : many studies have reported the increase in strength of the untrained contralateral limb after unilateral training . the aim of this study was to compare the cross education effect in the young and elderly persons . methods : in this quasi - experimental and pre - post study , 12 young people aged 28.25 3...
traditional cell culture surfaces can not provide sufficient control over the cellular microenvironment for use in studying many anchorage - dependent cellular processes such as cellular differentiation , proliferation , and phenotypic expression . cell supportive substrates , with the requisite spatiotemporal surf...
cell patterning has emerged as an elegant tool in developing cellular arrays , bioreactors , biosensors , and lab - on - chip devices and for use in engineering neotissue for repair or regeneration . in this study , micropatterned surfaces were created using the layer - by - layer lift - off ( lbl - lo ) method for a...
idiopathic congenital talipes equinovarus is a common condition affecting between 0.6 and 6.8 per 1,000 live births . the ponseti technique is well recognised in the management of clubfoot deformity with high success rates . this technique has decreased the need for extensive corrective surgery . following the seri...
introductionseveral studies have claimed ultrasound to be useful and accurate in assessing the healing phase of achilles tendons after tenotomy during ponseti treatment for clubfoot deformity . the purpose of our study was to assess the healing process of achilles tendons ultrasonographically after tenotomy as part o...
psammomatous melanotic schwannoma ( pms ) is a very rare pigmented tumor composed of schwann cells capable of melanogenesis . the histopathogenesis of this tumor is debatable considering the common neuroectodermal origin of melanocytes and schwann cells . pms arises most frequently from the spinal nerve roots and s...
psammomatous melanotic schwannoma ( pms ) is a rare pigmented tumor that can be part of the carney complex . here , we describe the case of a 35-year - old female patient presenting an isolated subcutaneous pms . histopathological analysis could not formally exclude the malignant nature of the tumor . the challengi...
large discrepancies have been reported for the prevalence of ed in the general population , and cv risk accounts for a significant part of this variability . over the age of 40 years , moderate to severe ed is reported in about 30 to 35% of men . however in men with hypertension the prevalence ranges from 26% to 68...
increased cardiovascular risk has been associated with reduced response to proerectile drugs . the italian society of andrology and sexual medicine ( siams ) promoted an independent , multicenter study performed in 604 men ( 55 12 yrs ) suffering from erectile dysfunction ( ed ) to assess multiple health outcomes a...
unprotected sexual contacts have remained one of the major routes of acquiring hiv and other sexually transmitted infections ( sti ) in the men who have sex with men ( msm ) population globally [ 14 ] . in hong kong , despite the low hiv prevalence in the general population , a rising trend of new hiv reports in msm ha...
background . community sampling of men having sex with men ( msm ) for human immunodeficiency virus ( hiv ) and sexually transmitted infections prevalence studies poses challenges in view of problems in logistics and the hidden nature of msm population . methods . msm in hong kong were recruited through social venues...
many clinically used drugs such as aspirin , digitoxin , progesterone , cortisone , morphine , vincristine , vinblastine , taxol and several others are derived directly or indirectly from higher plants . clinically important and well recognized drugs of fungal origin are penicillin , griseofulvin , ergot alkaloids an...
medicinal mushrooms occurring in south india namely ganoderma lucidum , phellinus rimosus , pleurotus florida and pleurotus pulmonaris possessed profound antioxidant and antitumor activities . this indicated that these mushrooms would be valuable sources of antioxidant and antitumor compounds . investigations also ...
in the standard model ( sm ) , direct production of e ( e ) pairs is forbidden in pp collisions due to lepton flavour conservation . however , in many extensions of the sm , lepton flavour violation ( lfv ) is permitted . in particular , r - parity - violating ( rpv ) supersymmetric ( susy ) models , lfv leptoquarks ...
this paper presents a search for the t - channel exchange of an r - parity violating scalar top quark ( \documentclass[12pt]{minimal } \usepackage{amsmath } \usepackage{wasysym } \usepackage{amsfonts } \usepackage{amssymb } \usepackage{amsbsy } \usepackage{mathrsfs } \usepackag...
creatine supplements are used as a possible performance - enhancing substance by athletes , bodybuilders , and others who wish to gain muscle mass . most of the studies that have examined the potential toxicity of creatine supplements have not found evidence of any side effects when consumed at recommended doses [ 14...
we report a case of a heretofore healthy 18-year - old man who presented with a 2-day history of nausea , vomiting and stomach ache while taking creatine monohydrate for bodybuilding purposes . the patient had acute renal failure , and a renal biopsy was performed to determine the cause of increased creatinine and pr...
echocardiography revealed the diagnosis of atrioventricular septal defect ( avsd ) with two adequate ventricles , closed atrial component and almost closed ventricular component , with what seemed to be aneurysmal tissue that had a tiny leak ( figures 1 , 2 ) . the patient also had a subaortic membrane with a peak gr...
the atrioventricular ( av ) valves are complex anatomical structures which perform sophisticated functions . 1 a wide spectrum of malformations of these valves can occur in patients with av septal defects . we here describe the anatomic and functional abnormalities of a rare form of the disease , where two valves...
acute ischemic stroke ( ais ) is a leading cause of death and permanent disability in china , and is also a cause of enormous financial burden for patients and society . currently , intravenous thrombolysis ( ivt ) with alteplase is the only approved therapy in patients with ais presenting within 4.5 hours after the ...
backgroundhyperhomocysteinemia ( hhcy ) is a well - known risk factor for ischemic stroke . however , whether hhcy can influence the treatment outcome of acute ischemic stroke ( ais ) patients has yet to be fully determined . in this study , we investigated the relationship between serum homocysteine ( hcy ) level an...
it is well established that our sensorimotor system adapts to a range of distortions in the environment , such as rotated visual feedback ( bock et al . 2002 ) and robotic force fields ( shadmehr and mussa - ivaldi 1994 ; tong et al . when the sensorimotor system is exposed first to distortion a and then to a disti...
the human sensorimotor system can concurrently adapt to two different distortions without interference when the distortions are cued by different contexts . we investigated whether this holds with four distortions as well . subjects were exposed to an interlaced sequence of + 30 , 30 , + 60 , and 60 visuomotor rota...
tumor lysis syndrome ( tls ) is a metabolic disorder caused by an exploding intracellular substance release that occurs when tumor cells lyse after the initiation of cytotoxic therapy ( 1 ) . tls is characterized by hyperuricemia , hyperkalemia , hyperphosphatemia , and hypocalcemia , metabolic abnormalities that can...
tumor lysis syndrome ( tls ) is a metabolic disorder that is generally associated with a malignancy leading to hyperuricemia , hyperphosphatemia , and acute kidney injury . on the other hand , we sometimes encounter these phenomena in nonmalignant disease , which has been referred to as tumor lysis - like syndrome in s...
age - related macular degeneration ( armd ) is the leading cause of blindness in developed countries.1 since 2005 , the advent of antivascular endothelial growth factor ( anti - vegf ) drugs for the treatment of the neovascular armd has changed the management of this disease . the prognosis of this disease has improv...
the authors describe one case of anterior uveitis after treatment of age - related macular degeneration with both antiangiogenic drugs : ranibizumab and bevacizumab . the case is described as a complication of ranibizumab and bevacizumab due to an inflammatory process . several reasons are suggested to explain this p...
equine influenza virus ( eiv ) causes common respiratory diseases in horses , donkeys , and mules . the horse population of north america suffered an epidemic of respiratory illnesses in 1872 , recorded as " the great epizootic of 1872 , " the cause of which was likely influenza a virus . equine respiratory disease...
this study provides information regarding vaccine research and the epidemiology of influenza virus in neglected hosts ( horses and dogs ) . equine influenza virus ( eiv ) causes a highly contagious disease in horses and other equids , and outbreaks have occurred worldwide . eiv has resulted in costly damage to the ho...
laparoscopic skill acquisition is an area of increasing interest . not only is the prevalence of laparoscopic surgery due to its minimally invasive nature expanding but expanding also are the questions and concerns regarding necessary preparation for the next generation of surgeons . in general , the current evaluati...
laparoscopic surgery is gaining popularity among the surgical community . while its prevalence expands , the need for reliable training and assessment tools is becoming increasingly important . laparoscopic skills are not an innate behavior , nor can they be easily mimicked , and can only be acquired through hands - ...
a major effort in functional glycomics is to catalog the specificities of glycan - binding proteins ( gbps ) toward the diversity of glycan structures found in biological systems . in nature , the typically weak binding interactions between gbps ( e.g. , lectins or antibodies ) and individual glycans are augm...
interactions of mucin glycoproteins with cognate receptors are dictated by the structures and spatial organization of glycans that decorate the mucin polypeptide backbone . the glycan - binding proteins , or lectins , that interact with mucins are often oligomeric receptors with multiple ligand binding doma...
infections preceding the ischemic stroke ( is ) , as well as infections occurring in the acute phase of is , are a frequent phenomenon [ 1 , 2 ] . chronic infections of both viral and bacterial etiology and coexistent vascular inflammatory state promote atherosclerosis , contributing to an increased cerebrovascular r...
background . infections increase the risk of ischemic stroke ( is ) and may worsen is prognosis . adverse effects of in - hospital infections on stroke outcome were also reported . we aimed to study the prevalence of pre- and poststroke infections and their impact on is outcome . methods . we analysed clinical ...
the hypothesis that there is a connection between the immune system and social behaviors such as mate choice mediated via olfactory cues is now nearly four decades old . this idea has not only fascinated numerous scientists stimulating an extensive number of experimental and theoretical studies but at the same time f...
genes of the major histocompatibility complex ( mhc ) , which play a critical role in immune recognition , are considered to influence social behaviors in mice , fish , humans , and other vertebrates via olfactory cues . as studied most extensively in mice , the polymorphism of mhc class i genes is considered to bring ...
the surgical options for the treatment of bone loss include bone transport , vascularized fibula graft , and induced membrane . interestingly patient sustained this injury in spite of having intramedullary nail in tibia which was inserted to stabilize previous fracture 9 months prior to trauma . the proximal half o...
introduction : the treatment of tibia bone loss can be challenging . the surgical options for the treatment of bone loss include bone transport , vascularized fibula graft , and induced membrane.case report : we present a case of complex compound fracture of tibia with bone loss . interestingly patient sustained th...
neuroleptic malignant syndrome ( nms ) was first recognized in 1956 by ayd but was only defined in 1960 by delay and deniker.1 ) nms is a rarely encountered , life threatening complication that usually appears within the first two weeks of antipsychotic therapy.2 ) moreover , nms cases due to certain antidepressants , ...
neuroleptic malignant syndrome ( nms ) is a life - threatening idiosyncratic reaction that usually occurs after the administration of antipsychotic drugs . antidepressants , benzodiazepines , and antiepileptic drugs are also suggested to be associated with nms . it is believed to result from a dopaminergic blockade...
lysine acetylation plays a critical role in the regulation of transcription , metabolism , and other central biological functions . acetylation of lysine residues can impact protein and genome function through multiple mechanisms , including physical relaxation of histone dna interactions , recruitment of br...
lysine acetyltransferases ( kats ) play a critical role in the regulation of gene expression , metabolism , and other key cellular functions . one shortcoming of traditional kat assays is their inability to study kat activity in complex settings , a limitation that hinders efforts at kat discovery , character...
the rapidly evolving field of materials science is providing dentistry with new treatments and alternatives . , much attention has been paid to calcium phosphate cements ( cpcs ) because of their advantages in comparison with calcium phosphate bioceramics , regarding in situ handling and shaping abilities [ 1 , 2 ] ....
aim . physicochemical mechanical and in vitro biological properties of novel formulations of polymeric calcium phosphate cements ( cpcs ) were investigated . methods . monocalcium phosphate , calcium oxide , and synthetic hydroxyapatite were combined with either modified polyacrylic acid , light activated polyalk...
vascular involvement is a key factor in major manifestations of systemic sclerosis ( ssc ) , such as raynaud 's phenomenon ( rp ) , myocardial dysfunction , pulmonary hypertension , and renal involvement . microvascular involvement , in which endothelial injury is present , is the main characteristic of ssc [ 1 , 2 ]...
objective . to investigate whether advanced glycation endproducts ( ages ) in the skin are increased in patients with systemic sclerosis ( ssc ) and are related to the presence of disease - related and traditional cardiovascular risk factors . methods . skin autofluorescence , as a measure for the accumulation of a...
presently , more than 100 different human papillomavirus ( hpv ) types have been discovered . among these , at least 30 different types of hpvs are known to cause cancers in the cervix , vagina , anus and penis as well as genital warts in the form of sexually transmitted diseases . in particular , a high oncologica...
human papillomavirus ( hpv ) infection is a major cause of cervical cancer and its precancerous diseases . cervical cancer is the second deadliest cancer killer among women worldwide . moreover , hpv is also known to be a causative agent of oral , pharyngeal , anal and genital cancer . recent application of hpv s...
due to its significant contribution to stratospheric ozone depletion and its potent greenhouse effect , nitrous oxide has stimulated much research interest regarding its reactivity modes and its transformations , which can lead to its abatement . we report the homogeneously catalyzed reaction of nitrous oxide...
clinically , ventilator - associated pneumonia ( vap ) is defined by the presence of new or progressive radiographic infiltrates plus clinical evidence that these infiltrates are of infectious origin . the presence of an infiltrate plus at least two out of three clinical features ( abnormal temperature [ > 38c or < 3...
the sensitivity and specificity of the radiographic and clinical evidence used to diagnose ventilator - associated pneumonia vary depending on the number of clinical criteria present . bacteriological confirmation that rules out other diseases can be achieved by quantitative or qualitative cultures of tracheal aspira...
this study was approved by the ajou university hospital institutional review board ( ajirb - bmr - obs-13 - 342 ) . cytology samples were obtained from fresh ex vivo ptc tissues immediately following surgical resection in cases that provided informed consent . after gross examination of fresh ptc specimens , cytolo...
background : recently , ve1 , a monoclonal antibody against the brafv600e mutant protein , has been investigated in terms of its detection of the brafv600e mutation . although ve1 immunostaining and molecular methods used to assess papillary thyroid carcinoma in surgical specimens are in good agreement , evaluation o...
laugier - hunziker syndrome is a rare acquired disorder characterized by macular hyperpigmentation of the oral mucosa and sometimes genital mucosa as well as longitudinal melanonychia . we report on a woman who concomitantly developed laugier - hunziker syndrome and a carcinoma of the pancreas . a 61-year - old cau...
laugier - hunziker syndrome is a rare acquired disorder characterized by macular hyperpigmentation of the oral and occasionally genital mucosa as well as longitudinal melanonychia . it is considered a benign condition without systemic manifestation or malignant potential . we report on a woman who concomitantly dev...
in a study by kurtz et al.1 ) based on the historical growth trajectory of arthroplasty surgeries , the demand for primary total hip and knee arthroplasty among patients less than 65 years old was projected to exceed 50% of the total hip and knee arthroplasty patients of all ages by 2011 and 2016 , respectively . pat...
high - flexion knee prosthesis was introduced with the aim of obtaining higher degree of flexion and good survivorship in patients with high functional demands or those requiring squatting , kneeling , etc . , which is more common in asians . based on all the research and experience with this prosthesis , it was co...
renal cell carcinoma ( rcc ) is one of the most common genitourinary malignancies , accounting for about 3 % of all cancers worldwide . clear cell renal cell carcinoma ( ccrcc ) is the most common histological type of renal cell carcinoma , also called conventional rcc , which represents 7580 % of rcc . initial t...
backgroundclear - cell renal cell carcinoma ( ccrcc ) is one of the most common types of kidney cancer in adults ; however , its causes are not completely understood . the study was designed to filter the key pathways and genes associated with the occurrence or development of ccrcc , acquaint its pathogenesis at gene...
chronic pain affects 1518% of the population . as well as allodynia , hyperalgesia , and spontaneous pain , patients with chronic pain also present with cognitive impairment , emotional change , insomnia , and mood disorders . currently , analgesic drugs are used primarily to treat pain but limited effects are a ma...
chronic pain is a major health issue and most patients suffer from spontaneous pain . previous studies suggest that huperzine a ( hup a ) , an alkaloid isolated from the chinese herb huperzia serrata , is a potent analgesic with few side effects . however , whether it alleviates spontaneous pain is unclear . we e...
the role of the adipokine leptin in the regulation of energy balance , has been firmly established since its discovery almost twenty years ago . animal models lacking either the leptin gene ( ob / ob mice ) or the gene encoding for its membrane receptor ( db / db mice ) are extremely obese , hyperinsulinemic and insu...
increased plasma levels of both leptin and c reactive protein ( crp ) have been reported in a number of conditions , including obesity , and have been linked to cardiovascular pathophysiological processes and increased cardiovascular risk ; interestingly these two biomarkers appear to be able to reciprocally regulate t...
the cerebellum has often been likened to a neuronal machine or computer with its precise geometrical array of intrinsic cell types that allow for the integration and organization of movement - related information through both of its afferent systems . ( 1967 ) posited that this system 's organization makes it uniquel...
in its strictest application , the term reinforcement learning refers to a computational approach to learning in which an agent ( often a machine ) interacts with a mutable environment to maximize reward through trial and error . the approach borrows essentials from several fields , most notably computer science , ...
nearly , 90% of americans would prefer to receive end - of - life care at home and one - third of americans die in the hospital , 20% of those in the intensive care unit ( icu ) . recent studies have shown that over 50% of end - of - life discussions take place for the first time in the hospital rather than in the ou...
background : studies have shown that over 50% of end - of - life discussions take place for the first time in the hospital and that terminally ill patients often have unrealistic views regarding the possible scope of treatment . the palliative care information act ( pcia ) was passed in an attempt to address the lack...
since the formation of the fick equation , physiologists have been trying to further enhance the knowledge base of heart rate , stroke volume , a - vo2 , and their relationship to vo2 . when considering maximal cardiorespiratory values , maximal vo2 ( vo2max ) is reached when maximal heart rate ( hrmax ) , maximal a ...
the purpose of the study was to determine if measured maximal heart rate ( hrmax ) was affected by sex or aerobic training status , and to determine the accuracy of three common clinical age - prediction maximal heart rate regression equations used to predict hrmax : hrmax = 220 age , hrmax = 226 age , and hrmax ...
murine ephrin - b2 ectodomain sequence ( amino acids 31227 ) was amplified from the plasmid pcdna3.1-ephrin - b2-hfc ( a kind gift from t. miyamoto , keio university ) , and human ephrin - b1 ectodomain sequence ( amino acids 28237 ) was amplified from palter - max ( a kind gift from h. sugimura , hamamatsu university ...
there is broad interest in designing nanostructured materials that can interact with cells and regulate key downstream functions17 . in particular , materials with nanoscale features may enable control over multivalent interactions , which involve the simultaneous binding of multiple ligands on one entity to multiple...
renal cell carcinoma ( rcc ) also known as hypernephroma or adenocarcinoma of renal cells is the most common type of kidney tumour found in adults . it originates in the proximal convoluted tubules , typically affecting men with a peak incidence in 5070 year olds . the tumour is recognized to metastasize to common ...
we present a case of a 64-year - old gentleman who developed a renal cell carcinoma ( rcc ) metastasis to his lower lip following successful treatment of the primary tumour . rcc is a common kidney tumour but skin metastases are considered rare . the authors describe the findings of this case and discuss the presen...
sur la scne internationale , il apparat de plus en plus clairement que le virus de lhpatite c ( vhc ) peut tre transmis sexuellement entre hommes positifs au vih ayant des relations sexuelles avec des hommes ( harsah ) . rendre compte de la premire estimation canadienne de la sro - incidence de vhc entre 2000 et 2010...
it has recently become clear that hepatitis c virus ( hcv ) can be sexually transmitted among men who have sex with men ; in fact , outbreaks of hcv in this population have been documented . sexual transmission was previously considered to be rare , but may be more common in this population due to both biological and...
the goal of image segmentation is to partition an image into a number of regions , each having similar characteristic . in the recent years active contours are based on the theory of surface evolution under a speed function determined by local , global and independent properties . they are able to provide smooth an...
this paper represents a new region - based active contour model that can be used to segment images with intensity non - uniformity and high - level noise . the main idea of our proposed method is to use gaussian distributions with different means and variances with incorporation of intensity non - uniformity model fo...
the procedures involving phlebotomy , for example , time of tourniquet application [ 14 ] and blood drawing using vacuum tubes [ 5 , 6 ] are poorly studied as potential sources of errors . in the daily practices of laboratory medicine , all diagnostic products can be divided into two major categories : in vitro diagn...
background and objective . some in vitro diagnostic devices ( e.g , blood collection vacuum tubes and syringes for blood analyses ) are not validated before the quality laboratory managers decide to start using or to change the brand . frequently , the laboratory or hospital managers select the vacuum tubes for blo...
the environmental mold aspergillus fumigatus has become the most important airborne fungal pathogen of humans and is the second most frequent cause of systemic fungal infections.(1 ) in immunocompetent individuals , a. fumigatus can cause allergic reactions and noninvasive infections such as aspergilloma . however , ...
the mold aspergillus fumigatus is the most important airborne fungal pathogen . adaptation to hypoxia represents an important virulence attribute for a. fumigatus . therefore , we aimed at obtaining a comprehensive overview about this process on the proteome level . to ensure highly reproducible growth conditions ,...
from september 2010 through march 2012 , rodents were trapped in rural residences from 2 county - level divisions ( xintai and daiyue ) in taian . after each rodent was numbered and species identified , the spleen was dissected for dna extraction . during 20102011 , scrub typhus patients from xintai and daiyue were r...
we screened orientia tsutsugamushi from 385 domestic rodents and 19 humans with scrub typhus in rural taian district , shandong province , a new scrub typhus epidemic area in northern china . sequence analysis identified 7 genotypes in the rodents , of which 2 were also identified in the humans .
angiodysplasia can be a major source of gastrointestinal bleeding , responsible for 6.0% of cases of lower gastrointestinal bleeding and 1.2 - 8.0% of cases of upper gastrointestinal bleeding . small bowel angiodysplasia includes a large number of cases of gastrointestinal bleeding of unknown origin , in approximatel...
angiography is a useful diagnostic tool in cases with massive gastrointestinal bleeding such as angiodysplasia and varicosis when endoscopy is not available . angiodysplasia and varicosis have distinguishable characteristic features on angiography , such as the presence of a nidus , visible late - draining veins , an...
medicaid was mentioned as the major source of health insurance by 9,230 persons from this survey ( 9.2 percent ) . of the 9,230 persons for whom medicaid was identified as the major source of health insurance , 5,137 or 55.7 percent were children under age 18 , and 44.3 percent were adults age 18 or over at the time ...
these data highlights are based on analysis of the 2001 national health interview survey ( nhis ) public use data ( http://www.cdc.gov/nchs/nhis.htm ) . nhis is a multi - purpose survey conducted by the national center for health statistics , centers for disease control and prevention . nhis has been conducted cont...
alloderm ( lifecell corp . ; brancburg , nj ) is an acellular dermal matrix ( adm ) obtained from cadaveric human skin that has been processed to remove all antigenic epitopes and cells , resulting in an immunologically inert scaffold ( 1 - 3 ) . the remaining dermal matrix contains collagen , elastin , hyaluronic ac...
alloderm ( lifecell corp . ; brancburg , nj ) is an acellular dermal matrix ( adm ) that serves as an immunologically inert scaffold in plastic surgery . in breast reconstruction , it is used as a filler for lumpectomy defects and can be used to create the inferolateral portion of the tissue expander pocket or implant ...
optical coherence tomography ( oct ) is a noninvasive imaging technique that enables in vivo cross - sectional visualization of biological tissue at micrometer resolution . low axial resolution of firstly developed octs ( 15 micrometers ) made them less useful in quantitative analysis of retinal layers ; however , curr...
this study was conducted to determine the thickness map of eleven retinal layers in normal subjects by spectral domain optical coherence tomography ( sd - oct ) and evaluate their association with sex and age . mean regional retinal thickness of 11 retinal layers was obtained by automatic three - dimensional diffusio...
supernumerary teeth may be defined as any teeth or tooth substance in excess of the full complement of primary and permanent teeth . most cases are found in association with syndromes such as gardner 's syndrome , cleidocranial dysostosis , and cleft lip and palate.[14 ] supernumerary teeth may occur as single ( 7686...
most supernumerary impacted teeth are located in the anterior maxillary region . they are classified according to their form and location . their presence may give rise to a variety of clinical problems . the detection of supernumerary teeth is best achieved by thorough clinical and radiographic examination . t...
rheumatoid arthritis ( ra ) is a chronic systemic disorder that causes destruction of joints through inflammation and proliferation of the synovial membrane [ 1 , 2 ] . in ra , the synovial tissue lining the joints becomes inflamed . in comparison with the normal synovial membrane , which is normally 1 - 2 cell layer...
emerging evidence suggests a role for sphingosine-1-phosphate ( s1p ) in various aspects of rheumatoid arthritis ( ra ) pathogenesis . in this study we compared the effect of chemical hypoxia induced by cobalt chloride ( cocl2 ) on the expression of s1p metabolic enzymes and cytokine / chemokine secretion in normal fib...
several adhesive systems are manufactured and investigated with the objective of seeking an effective bond to different dentinal substrates , resulting in different substrate conditioning techniques , and application modes of these systems . development efforts attempting to simplify the application procedure of adhe...
aim : this study assessed the effect of the dentin depth and the application mode on the hardness and elastic modulus of the adhesive layer.materials and methods : occlusal surfaces of 48 caries - free human third molars were removed , at two levels : superficial and deep dentin . for each type of surface , the test sp...
they can have any combination of dolichostenomelia , arachnodactyly , pectus deformities of the chest , mitral or aortic regurgitation , ectopia lentis , and mild joint laxity . other evidence of a generalized connective tissue disorder may be present such as scoliosis and skin striae . patients with marfan syndrom...
backgrounda leptosomic body type is tall and thin with long hands . marfanoid features may be familial in nature or pathological , as occurs in congenital contractual arachnodactyly ( beal s syndrome ) and shprintzen - goldberg syndrome mimicking some of the changes of marfan syndrome , although not accompanied by lu...
the ability of red blood cells to facilitate the journey of oxygen from the atmosphere to the mitochondrion has been repeatedly demonstrated in a vast literature of mammalian physiology . the physical characteristics of red cells and the properties of their contents allow these cells to increase the solubility of pla...
red cells are uniquely designed to transport oxygen and facilitate oxygen uptake by systemic tissues . blood transfusions are thus logical therapeutic choices in patients who exhibit signs of oxygen debt . a small number of studies that have addressed patients with metabolic or physiologic signs of oxygen debt or r...
the rural household biogas in china has rapidly developed in recent years . by 2010 , the number of rural household biogas users had reached 41.8 million in china [ 1 , 2 ] . however , the rural household biogas industry has been facing a fermented material shortage due to the changes in agricultural structure . more...
pretreatment technology is important to the direct methanation of straw . this study used fresh water , four bacterium agents ( stem rot agent , result microbe decomposition agent , straw pretreatment composite bacterium agent , and complex microorganism agent ) , biogas slurry , and two chemical reagents ( sodium ...
tomato ( solanum lycopersicum ) is one of the most important vegetable crops cultivated worldwide . tomato has a diploid ( 2n = 2x = 24 ) and relatively compact genome of approximately 950 mb . genetic linkage maps of tomato have been created by crossing cultivated tomato ( s. lycopersicum ) with several wild rel...
a total of 93,682 bac - end sequences ( bess ) were generated from a dwarf model tomato , cv . micro - tom . after removing repetitive sequences , the bess were similarity searched against the reference tomato genome of a standard cultivar , heinz 1706 . by referring to the heinz 1706 physical map and by elimi...
juvenile idiopathic arthritis ( jia ) covers a heterogeneous group of diseases which are similar in onset which is before the age of 16 and that they last for at least 6 weeks ( 1 ) . international league of associations for rheumatology ( ilar ) replaced juvenile chroni c arthritis ( jca ) , mostly used in europe , ...
background : juvenile idiopathic arthritis ( jia ) is one of the most common chronic rheumatic diseases inchildren with unknown etiology and pathogenesis . it also has no diagnostic test and its clinical diagnosis ismade through ruling out other types of arthritis . the aim of this study was to evaluate the level o...
poststroke depression ( psd ) is regarded as one the most common mental sequela of stroke patients1 . psd patients have low physical and cognitive function , and low self - worth compared to those with no depression2 , and they have a decreased quality of life3 . all these factors can have adverse effects...
[ purpose ] the purpose of the present study was to investigate the potential effects of circuit class training ( cct ) on poststroke depression through changes in branched - chain amino acids ( bcaas ) ( isoleucine , leucine , and valine ) and free - tryptophan ( f - trp ) . [ subjects ] the study subjects were ...
sjgren syndrome is chronic , systemic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands.1 thus , an elaborate involvement of the salivary and lacrimal glands leads eventually to , keratoconjuctivitis sicca and xerostomia . sjgren syndrome may occur in two forms : primary sjgren syndr...
sjgren syndrome is chronic , systemic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands . it is an elaborate involvement of the lacrimal and salivary glands , which eventually lead to keratoconjunctivitis sicca and xerostomia . it may occur in two forms - primary and secondary , wh...
an isolated cortical vein thrombosis ( icvt ) causing a venous hemorrhagic infarction without involving venous sinuses or deep cerebral veins is rare and accounts for less than 1% of strokes8 ) . an icvt is more difficult to diagnose than a cerebral venous thrombosis because the symptoms are non - specific and there ...
isolated cortical vein thrombosis ( icvt ) is a rare disease , accounting for less than 1% of strokes . a 46-year - old woman presented with progressive left side weakness . magnetic resonance ( mr ) imaging with t2 * -gradient echo ( t2 * -ge ) sequence showed long cord sign at the right frontal cortex . the pat...
production of extended - spectrum -lactamases ( esbls ) is the most common mechanism of resistance to third - generation cephalosporins among enterobacteriaceae including klebsiella pneumoniae and escherichia coli [ 1 , 2 ] . esbl determinants have been detected not only in clinical isolates but also in commensal bac...
production of extended - spectrum -lactamases ( esbls ) producing e. coli in animals and different methods of identifications from ado ekiti , ekiti state , nigeria , were investigated . three hundred and fifty fecal samples , collected from apparently healthy cattle and pigs , were cultured and identified following ...