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traditional herbal medicines are being increasingly studied on a scientific basis , and the benefits of a number of these medicines are being appreciated in the west . given the worldwide increases in cancer rates , the anti - tumor effects of some traditional herbal medicine have been attracting research attention , a... | objectives : oldenlandia diffusa is traditionally used to relieve the symptoms of and to treat various diseases , but its anti - cancer activity has not been well studied . in the present study ,
the authors investigated the anti - cancer effects of an ethanol extract of oldenlandia diffusa ( eod ) on ht-29 human ade... |
an accurate assessment of body composition is important to identify health risk associated with excessively high or low amounts of body fat , monitor changes in body composition associated with certain diseases , as an aid to developing weight loss or weight gain programs and assessing the effectiveness of nutrition an... | ultrasound has been used effectively to assess body fat for nearly 5 decades , yet this method is not known as well as many other body composition techniques . the purpose of this review is to explain the technical principles of the ultrasound method , explain the procedures for taking a measurement and interpreting th... |
the number of elderly americans will double to 80 million by 2050 ; the most expeditious growth is expected to occur between 2010 and 2030 , when the number of americans aged > 65 years will increase by 2.8% annually .
oldest old , or individuals > 85 years , are the most rapidly expanding subgroup of elderly citize... | the u.s . population is undergoing a dramatic shift in demographics , with a rise in the proportion of elderly americans . given an increased prevalence of thyroid disease and malignancy with age , understanding the safety of thyroid surgery in this age group is increasingly pertinent .
there remains disagreement reg... |
osteogenesis imperfecta ( oi ) is an inheritable bone disorder caused by abnormal synthesis of type - i collagen .
it is characterized by osseous fragility and ligamentous laxity , and classified into four types ( type i , mild ; ii , lethal ; iii , severe ; iv , moderate ) , based on clinical , radiographic , and ge... | abstractosteogenesis imperfecta ( oi ) is an inheritable bone disorder characterized by osseous fragility and ligamentous laxity .
it is sometimes difficult to obtain bone union in patients with oi .
the purpose of this report is to present a rare case of posttraumatic kyphosis due to a l1 burst fracture in a patie... |
the abdominal muscles are thought to both modulate and respond to changes in
intra - abdominal pressure ( iap ) with the diaphragm1 .
currently , increases in iap have been shown to occur as a reflex
response to external stresses placed on the lumbar spine .
therefore , co - contraction of the
abdominal muscl... | [ purpose ] it is well known that visual feedback is an important factor contributing to
balance and postural control . nevertheless , there has been little discussion about the
effects of visual feedback on pulmonary function .
this study was conducted to investigate
the role of visual feedback on respiratory ... |
all members of the nr superfamily display a highly conserved structural organisation with an amino terminal ab region ( that encodes activation function 1 , af-1 ) ; followed by the c - region which encodes the dna binding domain ( dbd ) ; a linker region d and the c - terminal e region .
the de region encodes the li... | nuclear hormone receptors ( nrs ) function as ligand dependent dna binding proteins that translate physiological / nutritional signals into gene regulation .
dysfunctional nr signaling leads to many disorders in reproduction , inflammation , and metabolism .
the opportunity to identify novel regulatory pathways in ... |
osteosarcoma ( os ) is derived from primitive bone - forming mesenchymal cells with the tendency for bone formation .
the os , the second most frequent primary malignant bone tumor , is usually found in long bones .
although it is the most common malignancy of long bones after multiple myeloma , it is a relatively ... | chondroblastic osteosarcoma ( cos ) , a subgroup of intramedullary osteosarcoma ( os ) , is the most common osteosarcoma that occurs in adolescents and early adulthood .
the cos has similar clinical and radiological features to those of conventional os .
we present a case of 20-year - old male patient with the chie... |
acinetobacter ( a. ) baumannii can be found in various environmental sources such as soil and foods , including vegetables , meat , and fish .
a. baumannii may infrequently colonize the skin of healthy human , typically at a low - density and for short - term duration .
colonization of other body sites , such as th... | objectives : acinetobacter baumannii is an omnipresent pathogen known as a major agent in healthcare and nosocomoal - associated infections . its ability to develop resistant pattern to the major and broad spectrum antibiotics is an important issue to be studied.methods:in this study , 101 strains of acinetobacter baum... |
p wave dispersion ( pwd ) is defined as the difference between the longest and the shortest pwave duration recorded from multiple different surface ecg leads . to date , the most extensive clinical evaluation of pwd has been performed in the assessment of the risk for atrial fibrillation ( af ) , which is characterized... | objectives : the association between p wave dispersion and iron deficiency anemia has not been documented in the literature . in this study , we evaluated p wave dispersion in patients with iron deficiency anemia and the possible relationships between p wave dispersion and other echocardiographic parameters.introductio... |
tubular colonic duplication in adults is rare and only a few cases have been reported in the literature .
when the colonic duplication is large and compounded by impacted large fecaloma , treatment with minimally invasive surgery may be difficult .
we report a case of a large tubular colonic duplication with impact... | tubular colonic duplication presenting in adults is rare and difficult to diagnose preoperatively .
only a few cases have been reported in the literature .
we report a case of a 29-year - old lady presenting with a long history of chronic constipation , abdominal mass and repeated episodes of abdominal pain .
the... |
recent epidemiologic studies have shown that celiac disease ( cd ) is more common than previously thought and may affect approximately 1% of the general population .
enteropathy - associated t - cell lymphoma ( eatl ) , a rare but well - documented complication of cd , is a high - grade t - cell non - hodgkin lymphom... | perforation of the small intestine is the most lethal complication following induction chemotherapy for enteropathy - associated t - cell lymphoma ( eatl ) .
we report a case of eatl with a near perforated jejunal ulcer , and suggest a novel approach towards its management . surgical resection followed by aggressive ... |
acute gastroenteritis can occur at any age , but the etiologic agents and the severity of the disease may vary depending on age ( 1 ) . several studies have shown that the most frequent causes of nonbacterial gastroenteritis are the rotavirus and enteric adenovirus , most particularly in children in the age range of 0 ... | backgroundacute gastroenteritis stemming from viral causes is very common during the childhood period .
rotavirus and enteric adenovirus are the most common factors of acute gastroenteritis encountered in infants and children . however , the epidemiology of rotavirus and enteric adenovirus gastroenteritis in the east... |
despite the improvements of restorative material in recent decades , the marginal
integrity of restorations remains a challenge for dentistry .
poor marginal adaptation
may produce marginal discoloration , postoperative sensibility , and secondary
caries .
the marginal
failure of composite resin restoration... | objective : this study evaluated the effect of the margin location and an adhesive system on
the marginal adaptation of composite restorations.material and methods : class v cavities were prepared in bovine teeth with the gingival margin on the
dentin and the incisal margin on the enamel . the cavities were restore... |
in colorectal surgery , intestinal anastomoses are being performed in lots of intestinal pathologies , mainly , malign colon tumors .
the complications observed after colon anastomoses are anastomotic leakage , fistula , hemorrhage , and anastomotic stricture .
the most common of such complications is anastomotic l... | aim . anastomotic leakage
after colon anastomosis is the most frequent and most feared complication with its highest mortality rate . in this study , we aimed to expose the impact of performing fibrin glue on sutured colocolic anastomosis , in the presence of experimental peritonitis , on anastomosis safety . method ... |
limited knowledge exists concerning the migration and health of women as children , adults , and elders .
existing models of women 's health and care fail to consider in their simplicity the cultural values , norms , structural facilitators , and constraints .
such models overlook the needs , responses , and experi... | demographers are slowly bringing the migration of women to the forefront as women become the majority of migrants worldwide .
migration can provide new opportunities for women on their own or jointly with their spouses to improve their lives , escape oppressive social relations , and support children and other family... |
balance is a generic term describing the dynamics of body posture involved in preventing a
fall .
balance disorders in stroke patients have a negative effect on activities of daily
living and functional independence levels1 , 2 . setting rehabilitation objectives as well
as assessing progress is dependent on th... | [ purpose ] the purpose of this study was to determine the correlation between the berg
balance scale ( bbs ) and acceleration of postural sway in the clinical test of sensory
interaction and balance ( ctsib ) by using a triaxial accelerometer for quantitative
assessment .
[ subjects and methods ] twenty - seve... |
azithromycin has been associated with prolongation of the qtc interval and development of torsades de pointes.previously , there were no data detailing the incidence of sustained ventricular tachycardia in patients with known prolonged qtc who were subsequently given azithromycin.in a small cohort of patients admitted ... | backgroundazithromycin has been associated with abnormalities of cardiac repolarization and development of torsades de pointes .
observational data suggest that the risk of death from cardiovascular causes is increased in patients taking azithromycin .
little is known regarding the risk of ventricular arrhythmia in... |
approximately , 50% of the world population and up to 90% of the population in developing countries rely on biomass fuels for everyday household energy needs .
biomass is any material derived from living or recently living material that may be used as fuel to be burned in a stove .
often , the stoves being used hav... | background : burning of biomass is widely used by the rural poor for energy generation . long term exposure to biomass smoke
is believed to affect lung function and cause respiratory symptoms.materials and methods : women with long term occupational exposure to burning firewood were recruited from a rural fishing com... |
the nuclear pore complex ( npc ) forms the conduit for the exchange of information between the nucleus and cytoplasm .
npc structures of amazingly similar appearance have been identified in all eukaryotes from yeast to human , yet differences in npcs between species are likely to provide important clues to npc functi... | nuclear pore complexes , the conduits for information exchange between the nucleus and cytoplasm , appear broadly similar in eukaryotes from yeast to human . precisely how nuclear pore complexes regulate macromolecular and ionic
traffic remains unknown , but recent advances in the identification and characterization ... |
acinic cell carcinomas ( accs ) are uncommon salivary gland tumors that most commonly occur during the fifth and sixth decades of life .
there are no clear characteristics of accs found on ct , mri and ultrasound imaging .
a 62-year - old female was referred to the ent service as a result of an incidental finding o... | we report on a patient who was referred to the ent service following an incidental finding on an mri scan of the brain .
it revealed a mass in the right parapharyngeal space , and additional imaging confirmed the presence of a solid cystic expansive mass with moderate enhancement following contrast media injection . ... |
in the previous issue of critical care , patel and colleagues report the result of a single - center study that randomized septic patients to atorvastatin or placebo .
the authors found that patients treated with statins had less transition to severe sepsis although mortality was no different between the treated and ... | several studies have shown promising results regarding the use of statins as an adjunctive treatment for sepsis .
most of those studies were retrospective or observational in nature .
the asepsis trial has reported that the administration of atorvastatin reduced clinical progression of sepsis but did not improve mo... |
in the previous issue of critical care , sakr and colleagues reported an epidemiologic study they performed in 24 intensive care units ( icus ) in the piedmont region of italy .
the study documents a lower prevalence of severe sepsis ( ss ) but a higher icu mortality in females than in males .
most previous studi... | epidemiological studies document that males are more prone than females to develop severe sepsis and this is confirmed by sakr and colleagues in the previous issue of critical care .
however , the impact of gender on prognosis of severe sepsis is a matter of debate .
sakr and colleagues report a higher mortality in... |
squamous cell carcinoma ( scc ) is the second most common type of skin cancer and is increasing in frequency every year [ 1 , 2 ] .
since we have no fully effective treatment for advanced scc , it is important to provide a definitive diagnosis and appropriate therapeutic intervention at an early stage .
ultraviolet... | increasing evidence has suggested that human papillomaviruses ( hpvs ) are linked to a large subset of numerous malignant tumors , including mucosal squamous cell carcinoma ( scc ) ; however , its involvement in cutaneous scc has not fully been elucidated .
cutaneous scc is the second most common type of skin cancer ... |
accordingly , cancer rehabilitation has been increasingly recognized as a key factor in the management of cancer survivors .
cancer rehabilitation involves helping cancer patients achieve maximum possible physical , social , psychological , and vocational functionality within the limits imposed by the disease and its... | purposethe purpose of this study was to assess clinical practice and barriers associated with cancer rehabilitation from the perspective of korean physiatrists.materials and methodsall active members of the korean academy of rehabilitation medicine were invited to complete an online survey developed after focus group d... |
the approach to portal hypertension ( ph ) in children has evolved significantly over the past half - century . with
improved endoscopic treatments for variceal bleeding , liver transplantation and transjugular intrahepatic portosystemic shunts ( tipss ) , the use of portal systemic shunts ( psss ) has been relegated... | purpose . review the safety and long - term success with portosystemic shunts in children at a single institution
. methods .
an irb - approved , retrospective chart review of all children ages 19 and undergoing surgical portosystemic shunt from january 1990september 2008 .
results .
ten patients were identifie... |
obsessive - compulsive disorder ( ocd ) is a common , neuropsychiatric disorder that can have debilitating effects on both genders throughout their life .
although selective serotonin reuptake inhibitors ( ssris ) and clomipramine are recommended as first - line agents for drug treatment of ocd , it is estimated that... | background : this study aimed to assess the efficacy of topiramate , a glutamate - modulating agent , in patients with treatment - resistant obsessive - compulsive disorder ( ocd ) as an adjunct to serotonin reuptake inhibitors ( sris).materials and methods : thirty - eight patients with refractory ocd , were randomly ... |
cardiac structure as determined by echocardiography , is a powerful independent predictor for cardiovascular disease ( cvd ) , morbidity , and mortality in african americans , including in the highrisk jackson cohort of the atherosclerosis risks in communities ( aric ) study .
this is of particular concern given the ... | backgroundthough left ventricular mass ( lvm ) predicts cardiovascular events ( cvd ) and mortality in african americans , limited data exists on factors contributing to change in lvm and its prognostic significance .
we hypothesized that baseline blood pressure ( bp ) and body mass index ( bmi ) and change in these ... |
negative side effects like the promotion of antibiotic resistance should be expected , but other changes in the host and its microbiota are harder to predict .
it is important to remember that antibiotics are nt simply impacting a potential pathogen ; they are also changing the ecology within the gut .
culturing fe... | antibiotics are an essential component of the modern lifestyle .
they improve our lives by treating disease , preventing disease , and in the case of agricultural animals by improving feed efficiency . however , antibiotic usage is not without collateral effects .
the development and spread of antibiotic resistance... |
a dentigerous cyst is an epithelial - lined developmental cavity that encloses the crown of an unerupted tooth at the cementoenamel junction .
dentigerous cysts are the second most common odontogenic cysts after radicular cysts , accounting for approximately 24% of all true cysts in the jaws .
their frequency in th... | a dentigerous cyst is an odontogenic cyst , thought to be of developmental origin .
it is associated with the crown of an unerupted ( or partially erupted ) tooth .
the cyst cavity is lined by epithelial cells derived from the reduced enamel epithelium of the tooth forming organ .
most dentigerous cysts are solit... |
nurses are regarded as an integral part of the healthcare system ( 1 ) , but , among them , psychological problems and occupational stress are very common ( 2 , 3 ) . the poor mental health of nurses imposes unfavorable effects on them and on the safety of patients under their care ( 4 , 5 ) .
nurses make errors and ... | introductionfrequent nursing errors are considered as factors that affect the quality of healthcare of patients .
capable nurses who are compatible with work conditions are more focused on their tasks , and this reduces their errors and cognitive failures .
therefore , this study was conducted with the aim of inves... |
gingival disease can progress to periodontitis which if left untreated may eventually compromise the entire periodontium .
however , mechanical plaque control by means of tooth brushing and flossing is not always completely effective as it is based on the dexterity and motivational level of individual .
moreover , ... | background : the intake of green tea has been increased recently due to its medicinal values .
the antibacterial and antioxidant properties of green tea were found to be beneficial in the treatment of gingival and periodontal diseases .
the aim of this comparative study was to compare the efficacy of the mouthwash ... |
traditional operation means open surgery , which believes big scar , big surgeon . with the appearance of laparoscopy , minimally invasive surgery ( mis ) opened a new era for surgery . in order to get a smaller invasion , surgeons invented laparoendoscopic single - site surgery ( less ) and natural orifice translumina... | background : magnetic anchored surgical instruments ( masi ) , relying on magnetic force , can break through the limitations of the single port approach in dexterity .
individual characteristic abdominal wall thickness ( icawt ) deeply influences magnetic force that determines the safety of masi .
the purpose of th... |
the prevalence of prostate cancer increases with age . fortunately , screening using prostate - specific antigen ( psa ) and transrectal prostate biopsies enables the early diagnosis and treatment of prostate cancer .
in addition , surgical treatments for localized prostate cancer are associated with safe and favorab... | purposeto evaluate the prevalence of bladder neck contracture ( bnc ) and its risk factors in patients undergoing radical prostatectomy in korea.materials and methodswe analyzed data from 488 patients with prostatic cancer who underwent radical prostatectomy performed by seven surgeons in seven hospitals , including 36... |
proton magnetic resonance spectroscopy ( h mrs ) is a method that allows for examination of brain function in vivo .
the most replicated finding relating to schizophrenia obtained by means of h mrs is a lower level of naa ( n - acetylaspartate ) in the dorsolateral prefrontal cortex , hippocampal area , temporal cort... | summarybackgroundproton magnetic resonance spectroscopy ( 1h mrs ) allows for examining brain functions in vivo in schizophrenic patients .
correlations between n - acetylaspartate ( naa ) level in the frontal lobe and cognitive functions and clinical symptoms have been observed .
the aim of the present study was e... |
leukemia is a kind of cancer that begins in cells that form new blood cells .
these cells are detected in the soft , inner part of the bones called the bone marrow .
patients with chronic lymphocytic leukemia ( cll ) were first described in the early nineteenth century ( 1 - 3 ) .
the natural history of the disea... | background : b - cell chronic lymphocytic leukemia ( b - cll ) is the most common form of leukemia in adults .
some reports showed that expression of zap70 gene and chromosomal abnormality are two prognostic factors in management of b - cllobjectives : in this study , we determined zap70 mrna expression level in the ... |
blue rubber bleb nevus syndrome ( brbns ) is a rare systemic vascular disorder characterized by multiple venous malformations , such as hemangioma , involving many organs .
approximately 200 cases of brbns including 13 korean cases have been reported since gascoyen 's first presentation in 1860 .
brbns can occur in... | blue rubber bleb nevus syndrome ( brbns ) is a rare systemic vascular disorder characterized by multiple venous malformations involving many organs .
brbns can occur in various organs , but the most frequently involved organs are the skin and gastrointestinal ( gi ) tract .
gi lesions of brbns can cause acute or ch... |
periodontitis is a multifactorial disease with microbial dental plaque as an initiator but is influenced by a wide variety of factors including subject characteristics , social and behavioral factors , systemic factors , genetic factors , tooth level factors , microbial composition of dental plaque .
periodontitis wa... | background : the aim of the present study was to compare various risk indicators of chronic periodontitis ( cp ) and aggressive periodontitis ( ap ) among patients of davangere population.materials and methods : totally , 89 cp and 90 ap patients were selected from outpatient department of periodontics , college of den... |
multiple sclerosis ( ms ) is a chronic inflammatory disease affecting the brain and spinal cord1 leading to muscle weakness , coordination and balance problems , as well as sensation disorders , visual and cognitive deficits , and gradual limitation of functioning.2 subjects with ms have multiple risk factors for osteo... | multiple sclerosis ( ms ) affects the central nervous system leading to disability and is complicated by bone loss and fractures . despite the acceptance of osteoporosis and fractures as two major public health problems , in people with ms the mechanisms have not been investigated adequately .
physicians and patients... |
fatty liver ( hepatic lipidosis ) and ketosis ( elevated concentrations of ketone bodies in blood , milk , urine , and other body fluids ) are metabolic alterations that occur in high producing dairy cows during the periparturient period .
although distinctly different , they are both part of a generalized lipid mobi... | the present on - farm research evaluated the occurrence of fatty liver syndrome and its predisposing risk factors for multiparous dairy cows from a commercial herd in venezuela .
liver biopsy samples were collected at 35 days ( d ) prepartum ( holstein , n = 14 ; holstein carora crossbred , n = 17 ) as well as 1 to ... |
aggregation or sex pheromones produced by males have been identified for 12 species of longhorned beetles of the subfamily cerambycinae ( coleoptera : cerambycidae ; lacey et al . 2004 , 2007b ; hanks et al . 2007 ; ray et al . 2009a , b , and references therein ) .
pheromone components of most of these species are t... | adults of both sexes of the cerambycid beetles xylotrechus colonus ( f. ) and sarosesthes fulminans ( f. ) were attracted to odors produced by male conspecifics in olfactometer bioassays .
analyses of headspace volatiles from adults revealed that male x. colonus produced a blend of ( r)- and ( s)-3-hydroxyhexan-2-one... |
organic matter ( om ) remineralization is a key function of the benthic compartment of marine ecosystems and although extensively studied , it remains a subject of focus due to the complexity of factors and processes involved ( wakeham and canuel 2006 ) .
it is generally thought that microbes fulfill a key role in om... | organic matter ( om ) remineralization may be considered a key function of the benthic compartment of marine ecosystems and in this study we investigated if the input of labile organic carbon alters mineralization of indigenous sediment om ( om priming ) . using 13c - enriched diatoms as labile tracer carbon , we exami... |
the design of materials for controlled drug delivery has been growing in the last years , due to their importance in the pharmaceutical and health industry .
mesoporous and microporous materials are potentially interesting systems for this purpose due to their high surface area , pore size , structure stability [ 1 ,... | meso- and nanoporous structures are adequate matrices for controlled drug delivery systems , due to their large surface areas and to their bioactive and biocompatibility properties .
mesoporous materials of type sba-15 , synthesized under different ph conditions , and zeolite beta were studied in order to compare the... |
supplementary material is available for this article at 10.1007/s13659 - 012 - 0026-z and is accessible for authorized users .
| three new sesquilignans , 13 , a new sesquiterpenoid , 4 , and three known compounds were isolated from the stem barks of illicium simonsii .
the structures of new compounds ( 14 ) were elucidated by spectroscopic methods .
a biosynthetic pathway was proposed for simonsienols a - c ( 13 ) .
anti - ache activity a... |
clavicle fractures are commonly found in all age groups.1 these fractures account for 5 to 10% of all fractures1,2 and represent 45 to 50% of all shoulder girdle injuries.1,3 clavicle fractures are common , and reports have noted that their annual incidence varies from 29 to 64 per 100,000 individuals , and they accoun... | objective : the main aim of the study was to analyze the outcomes of clavicle fractures in adults treated non - surgically and to evaluate the clinical effects of displacement , fracture patterns , fracture location , fracture comminution , shortening and fracture union on shoulder function.methods:seventy clavicle fra... |
sampling and species - specific identifications of rodents - from
2009 - 2011 , a multi - approach monitoring of urban rodents was performed in order to
address several issues including epidemiological ones .
to do so , more than 14,560
night - traps were performed using both sherman and locally made wire - mes... | a serological survey of toxoplasma gondii was
conducted on 766 domestic and peridomestic rodents from 46 trapping sites
throughout the city of niamey , niger .
a low seroprevalence was found over the
whole town with only 1.96% of the rodents found seropositive . however ,
differences between species were impo... |
the chlorophenoxy herbicides mcpa and 2,4-d are registered for a range of agricultural and residential uses focused on control of postemergent broadleaf weeds . since 2001 , 2,4-d has been the most commonly used herbicide in the residential market at 8 to 11 million pounds annually and is the seventh most commonly used... | chlorophenoxy compounds , particularly 2,4-dichlorophenoxyacetic acid ( 2,4-d ) and 4-chloro-2-methylphenoxy)acetic acid ( mcpa ) , are amongst the most widely used herbicides in the united states for both agricultural and residential applications .
epidemiologic studies suggest that exposure to 2,4-d and mcpa may be... |
bone grafts represent one of the earliest devised reconstructive approaches for the musculoskeletal system and remain among the most common orthopaedic procedures , being used for the repair of fractures , arthrodeses , and cystic defects , and skeletal deficits after traumatic loss or tumor resection . to eliminate po... | to eliminate the potential for infection , many tissue banks routinely process and terminally sterilize allografts prior to transplantation .
a number of techniques , including the use of scanning electron microscopy , bone graft models , and mechanical property tests , are used to evaluate the properties of allograf... |
hyperglycemia during the diabetes has detrimental effects on various organs including eye , kidney , central nervous system , and heart .
hyperglycemia favors the insurgence of coronary artery disease , peripheral arterial diseases , cardiomyopathy , angina , and myocardial infarction . among these , the most dangero... | this study investigated the effects of the new aldose reductase inhibitor benzofuroxane derivative 5(6)-(benzo[d]thiazol-2-ylmethoxy)benzofuroxane ( bf-5 m ) on the prolongation of cardiac qt interval and increase of coronary perfusion pressure ( cpp ) in isolated , high glucose ( 33.3 mm d - glucose ) perfused rat he... |
hearing loss is one of the common sensory disorders in humans , affecting 1 in 1000 newborns .
more than one half of it may attribute to genetic factors . among them , it showed that hearing loss is transmitted with a heredity form concurrent with autosomal recessive ( 75% ) , dominant ( 20% ) , x - linked ( 3% ) , a... | background : the molecular genetic research showed the association between x - linked hearing loss and mutations in pou3f4 .
this research aimed to identify a pou3f4 mutation in a nonsyndromic x - linked recessive hearing loss family.methods:a series of clinical evaluations including medical history , otologic examin... |
the benefits of ultrasound - guided hysteroscopic metroplasty have been well described in the management of the partial septate uterus .
the use of ultrasonography at the time of hysteroscopy provides visualization of the intrauterine instruments within the uterine cavity .
this report describes a case where ultras... | background : the benefits of ultrasound - guided hysteroscopic metroplasty have been well described in the management of the partial septate uterus . the use of ultrasonography at the time of hysteroscopy provides visualization of the intrauterine instruments within the uterine cavity .
this report describes a case w... |
glycogen synthase kinase 3 ( gsk3 ) has been shown over the past three decades to regulate a myriad of cellular functions including cell polarity , cell fate , metabolic homeostasis , development , apoptosis , microtubule function , and neuronal growth and differentiation .
elegant cellular checkpoints and highly reg... | the constitutively active protein glycogen synthase kinase 3 ( gsk3 ) , a serine / threonine kinase , acts paradoxically as a tumor suppressor in some cancers while potentiates growth in others .
deciphering what governs its actions is vital for understanding many pathological conditions , including brain cancer .
... |
in november 2006 , a 23-year - old woman referred to the department of dermatology of bologna university with a two - month - history of a softy painless nodule located on the right cheek ( figure 1 ) .
physical examination revealed a yellowish lesion that showed a central ulceration measuring 2 cm across and infiltr... | piloleimyoma is a type of cutaneous leiomyoma arising from arrectores pilorum .
it can present as either a solitary nodule or multiple lesions .
usually it is localized on the extremities , but can also occur on trunk , neck area and face .
lesions are usually cold , ulcerated and spontaneously painful .
herein... |
complications during percutaneous coronary intervention ( pci ) include coronary artery complications ( perforation , distal embolization , side branch occlusion , and stent thrombosis ) and vascular complications ( puncture site hematoma , retroperitoneal bleeding , and atheroembolism ) . among them , stent entrapment... | although stent entrapment is a rare event during percutaneous coronary intervention , stent entrapment can cause stent breakage or loss , which results in fatal complications such as stent embolism or acute myocardial infarction .
we report one case of stent entrapment that was successfully treated by a snare via a c... |
human primary cells
and cell lines are
believed to express between
8000 and 11 000 gene products dependent on their differentiation
state .
modern proteomic workflows are now able to cover
deep cellular proteomes through prefractionation and multienzyme digestion
strategies .
however , most proteins ar... | the
deep proteome has been accessible by mass spectrometry
for some time .
however , the number of proteins identified in cells
of the same type has plateaued at 800010 000
without i d transfer from reference proteomes / data . moreover , limited
sequence coverage hampers the discrimination of protein is... |
y.k . is supported by a grant - in - aid for scientific research on innovative areas nanomedicine molecular science ( no .
2306 ) from the ministry of education , culture , sports , science , and technology of japan . | abstractneurons can extend branches from a single axon to send signals to multiple target cells .
axonal arbor morphology must be changed to establish and alternate neuronal wiring properly . for this purpose , the elongation and retraction rate of each terminal in a single axonal arbor
are differentially regulated... |
congenital diaphragmatic hernia ( cdh ) is a congenital malformation of diaphragm , characterized by a defect in the diaphragm along with herniation of gastro - intestinal loops and other abdominal viscera into the thoracic cavity . in case of extreme maldevelopment of diaphragm
, there might be a complete agenesis o... | congenital diaphragmatic hernia is a congenital defect of the diaphragm through which intestine and other viscera herniate into the chest . in extreme form of diaphragmatic maldevelopment
, there might be a complete agenesis of diaphragm .
a 45-day old male infant was presented with fever , cough and respiratory di... |
hart - d was a 9-month exercise study comparing the effects of aerobic , resistance , or a combination of both on hba1c measures in sedentary individuals with type 2 diabetes .
the methods and main outcomes for hart - d have been previously published ( 16 ) .
a total of 262 sedentary adults with hba1c levels of 6.5... | objectiveto establish whether exercise improves quality of life ( qol ) in individuals with type 2 diabetes and which exercise modalities are involved.research design and methodshealth benefits of aerobic and resistance training in individuals with type 2 diabetes ( hart - d ; n = 262 ) was a 9-month exercise study com... |
the biocompatibility of dental materials has been theme of great speculation and uncertainty . there are , particularly in orthodontics , several materials keeping direct contact with organic tissues for long periods of time .
pre - vulcanized latex is produced by mixing pure natural latex , which has the highest mol... | objectives : natural latex does not fall into the category of materials known to be entirely inoffensive . the purpose of this in vitro study was to test the hypothesis that there is no difference in the cytotoxicity between elastics of different colors and those from different manufacturers.material and methods : diff... |
heme - containing proteins form a vast and biologically important superfamily : they are found in all living species and carry out a very wide array of functions .
the most well studied examples are the o2 transport proteins ( the globins ) , the electron transfer proteins ( the cytochromes ) , and the various cataly... | we describe a simple method for the determination of heme protein reduction potentials .
we use the method to determine the reduction potentials for the pas - a domains of the regulatory heme proteins human npas2 ( em = 115 mv 2 mv , ph 7.0 ) and human clock ( em = 111 mv 2 mv , ph 7.0 ) .
we suggest that the met... |
the estrogen receptor ( er ) is a ligand - inducible intracellular transcription factor that mediates most of the biological effects of estrogens at the level of gene regulation [ 13 ] .
estrogen biology is exceedingly complex and important in the development and function of numerous tissues and physiological phenome... | the estrogen receptor ( er ) mediates most of the biological effects of estrogens at the level of gene regulation by interacting through its site - specific dna and with other coregulatory proteins . in recent years ,
new information regarding the dynamic structural nature of er has emerged .
the physiological effe... |
colorectal cancer ( crc ) is the third most commonly diagnosed cancer in males and the second in females worldwide [ 1 , 2 ] and the incidence rate and mortality rate attributed to crc have been increasing in recent years in china . for the treatment of advanced crc ,
chemotherapy is recommended and oxaliplatin - bas... | aim . to investigate the correlation between ppp1r12a gene copy number and clinical outcomes of oxaliplatin - based regimen in stage iii colorectal cancer ( crc )
. methods . a total of 139 paraffin - embedded tissue samples of stage iii crc patients who received oxaliplatin - based treatment after radical surgery we... |
classical intrafascial supracervical hysterectomy ( cish ) was first described and performed by kurt semm from kiel , germany .
we began utilizing this technique at fayette medical center ( fmc ) , fayette , alabama , usa in 1992 and have performed more than 500 cish procedures since then .
fayette medical center i... | objective : patients demand that health care and procedures in rural areas be provided by ambulatory surgery centers close to home .
however , the reimbursement rate for such procedures in ambulatory centers is extremely low , so a standard classic intrafascial supracervical hysterectomy procedure needs to be more co... |
thirty one cases of pathologically proven gastric cancer occurring from march 2002 to march 2005 were prospectively included in this study .
the patient records and the pertinent clinical data are shown in table 1 and include tumor size ( greatest diameter ) , pathological tnm ( ptnm ) staging ( uicc 1997 ) and who h... | objectiveto investigate the relationship between the perfusion ct features and the clinicopathologically determined prognostic factors in advanced gastric cancer cases.materials and methodsa perfusion ct was performed on 31 patients with gastric cancer one week before surgery using a 16-channel multi - detector ct ( md... |
leiomyosarcoma of the mediastinum and primary leiomyosarcoma of the spine are exceedingly rare [ 1 - 6 ] .
mediastinal leiomyosarcoma accounts for only about 11% of primary mediastinal sarcomas ; therefore , the treatment strategy is not well established . despite an aggressive surgical approach , as well as the use ... | leiomyosarcoma of the mediastinum and primary leiomyosarcoma of the spine are exceedingly rare . in most cases ,
spinal leiomyosarcoma is metastatic . in this report
, we describe the case of a 58-year - old man who presented with a large leiomyosarcoma of the posterior mediastinum that extended into the adjacent s... |
a case - patient was defined as a resident of norway with y. enterocolitica o:9 isolated from stool or blood and with illness onset between december 15 , 2005 , to february 15 , 2006 .
cases were identified through the national surveillance system at niph , which receives reports of laboratory - confirmed cases from ... | an outbreak involving 11 persons infected with yersinia enterocolitica o:9 was investigated in norway in february 2006 .
a case - control study and microbiologic investigation indicated a ready - to - eat pork product as the probable source .
appropriate control measures are needed to address consumer risk associat... |
muscle damage and delayed onset muscle soreness ( doms ) may occur at different levels
depending on the type of contraction ( concentric or eccentric ) , type of exercise ( plyometric
jumps , resistance training , downhill runs , long - term runs , etc . ) , movement speed ( high or
low angular velocity ) , time ... | [ purpose ] it is believed that eccentric high - intensity exercise can decrease performance
in subsequent exercise . however , with repetition , the deleterious effects can be
minimized .
thus , this study evaluated the influence of repeated bouts of eccentric
exercise on subsequent high - intensity aerobic pe... |
a 78-year - old average - built man with previous history of coronary artery disease was hospitalized with chest pain of few hours duration .
thorough investigation had revealed carotid hypersensitivity ( 3 second pause after right carotid massage ) and mixed cardioinhibitory and vasodepressor response to upright til... | proximal right coronary artery occlusion caused transient loss of sensing and capture of the atrial lead of a permanent dual - chamber pacemaker .
forty - five days after percutaneous revascularization , the atrial lead was discovered to be functioning normally .
we hypothesize that ischemia of the right atrium cau... |
intravenous tissue plasminogen activator ( iv - tpa ) improves outcomes of patients with acute ischemic stroke , but has the risk of symptomatic intracranial hemorrhage ( sich ) .
iv - tpa therapy is not recommended in patients with current use of warfarin therapy with internationalized normal range > 1.7 or use of n... | background and purposeabout 30%-40% of stroke patients are taking antiplatelet at the time of their strokes , which might increase the risk of symptomatic intracranial hemorrhage ( sich ) with intravenous tissue plasminogen activator ( iv - tpa ) therapy .
we aimed to assess the effect of prestroke antiplatelet on th... |
the trapezius muscle , which adjusts the movement and location of the scapula , plays an
important role in both the stability and movement of the shoulder joints and , therefore , is
a crucial muscle for optimal upper extremity function1 .
the trapezius changes the location of the glenoid fossa during
shoulder ... | [ purpose ] this study examined the differences in the activities of three parts of the
trapezius muscle the upper trapezius ( ut ) , middle trapezius ( mt ) , and lower trapezius
( lt)among three different rotation conditions of the shoulders , while subjects performed
prone horizontal abduction ( pha ) at 30 ,... |
fear conditioning is a type of associative learning that is widely studied as a model of learning and memory across a variety of species .
fear conditioning has been extensively characterized at the behavioral level , particularly auditory fear conditioning , in which a tone ( cs ; conditioned stimulus ) is paired wi... | long - term potentiation ( ltp ) at thalamic input synapses to the lateral nucleus of the amygdala ( la ) has been proposed as a cellular mechanism of the formation of auditory fear memories .
we have previously shown that signaling via erk / mapk in both the la and the medial division of the medial geniculate nucleu... |
heme and nonheme iron monoxygenases and dioxygenases are unique classes of biological catalysts , which drive vital reactions for human health and as a consequence they are found in most biosystems ranging from bacteria to mammals .
the nonheme iron dioxygenases bind and utilize molecular oxygen on an iron center and... | heme and nonheme monoxygenases and dioxygenases catalyze important oxygen atom transfer reactions to substrates in the body .
it is now well established that the cytochrome p450 enzymes react through the formation of a high - valent iron(iv)oxo heme cation radical .
its precursor in the catalytic cycle , the iron(i... |
by 2030 , the number of americans age 65 or over is expected to reach 71 million , double the 34.8 million documented in the year 2000 , causing an unprecedented shift in the age structure of the u.s . population ( centers for disease control and prevention , 2007 ) .
an individual reaching age 65 today could expect ... | this study examined the physical and mental health of 126,685 males and females age 65 or over , with and without cancer that completed a medicare health outcomes survey ( mhos ) between 1998 - 2002 .
cancer information was ascertained through the national cancer institute 's ( nci 's ) surveillance , epidemiology an... |
however , the decision to remove or to retain the cervix is still a matter of controversy . advocates claim that retention of the cervix has advantages regarding urinary , bowel and sexual function . in our private practice ,
the purpose of this study was to describe our early experience with lash for uterine non - m... | objectives : to evaluate our experience with laparoscopic supracervical hysterectomy ( lash ) and to assess the short- and medium - term outcome.methods:retrospective analysis of patient and surgery characteristics from chart review and evaluation of patient satisfaction by a questionnaire.results:forty-one patients wh... |
hemimegalencephaly ( hme ) and seizure episodes have been reported previously in a few cases with ktws .
we report here a 3 day - old girl with partial motor seizures , extensive port - wine staining and mild structural deformities in the feet , and a hemimegalencephaly .
occurrence of partial motor seizures in add... | backgroundklippel - trenaunay - weber syndrome ( ktws ) is a rare neurocutaneous syndrome .
hemimegalencephaly ( hme ) and seizure episodes have been reported previously in a few cases with ktws.case presentationwe report here a 3 day - old girl with partial motor seizures , extensive port - wine staining and mild st... |
around 33.4 million people were living with hiv in year 2008 and around 2 million people have died in the same year . highly active antiretroviral therapy ( haart )
has brought new hope for those people who live with hiv / aids by decreasing the morbidity and mortality among people infected with hiv .
highly active... | developing a single analytical method for estimation of individual drug from a multidrug composition is a very challenging task .
a complexation , derivatization , extraction , evaporation , and sensitive - free direct uv spectrophotometric method is developed and validated for the simultaneous estimation of some ant... |
in 2002 , the ministry of health and long term care ( mohltc ) of ontario conducted a review of primary studies on endovascular repair ( evar ) for abdominal aortic aneurysms ( aaa ) as well as a review of previous international and canadian health technology assessments ( hta ) . due to the informational uncertainty a... | background . this paper presents unpublished clinical and economic data associated with open surgical repair ( osr ) in low risk ( lr ) patients and how it compares with evar and osr in high risk ( hr ) patients with an aaa > 5.5 cm . design .
data from a 1-year prospective observational study was used to compare ev... |
cardiomyopathy is characterized by the progressive remodeling of the ventricles and affects the conduction pathway .
disturbances in cardiac bundles and fascicles cause a delay in the onset of right and left ventricular ( lv ) contractions , named dyssynchrony .
several echocardiographic methods ( conventional and ... | background : several echocardiographic markers have been introduced to assess the left ventricular ( lv ) mechanical dyssynchrony . we studied dyssynchrony markers and the latest lv activation site in heart failure patients with and without left bundle branch block ( lbbb).methods : conventional echocardiography and ti... |
using the cloth - dragging method , during march may 2007 we collected 100 adult dermacentor spp . ticks from meadows in 2 different locations near cakovec , between the drava and mura rivers in the central part of medjimurje county .
this area is situated in the northwestern part of croatia , at 4638n , 1643e , and... | we report on the molecular evidence that dermacentor reticulatus ticks in croatia are infected with rickettsia helvetica ( 10% ) or rickettsia slovaca ( 2% ) or co - infected with both species ( 1% ) .
these findings expand the knowledge of the geographic distribution of r. helvetica and d. reticulatus ticks . |
cervical cancer is the second most common cancer in women worldwide and remains a major cause of morbidity and mortality .
since the pap test was introduced in the 1940s , there has been an approximately 70% reduction in the incidence of squamous cell cervical cancers in many developed countries by the application of... | since the pap test was introduced in the 1940s , there has been an approximately 70% reduction in the incidence of squamous cell cervical cancers in many developed countries by the application of organized and opportunistic screening programs .
the efficacy of the pap test , however , is hampered by high interobserve... |
however , they are relatively more often seen in children . most often , these arise from the lateral ventricular walls . meningiomas of the velum interpositum are extremely unusual and difficult to diagnose .
these arise from the arachnoid cap cells within the potential space of the velum interpositum and lack a dur... | intraventricular meningiomas are rare , but are relatively more often seen in children
. large size at presentation often obscures anatomical details .
a particular subset of such tumors arising from the velum interpositum pose a significant surgical challenge .
thorough preoperative imaging , especially with res... |
israel passed a health insurance law in 1995 that mandates healthcare services by healthcare funds ( hmos ) for the entire population .
there is competition among the funds to improve efficiency and provide optimal care to the satisfaction of their patients , while still meeting budgetary constraints .
one of the w... | objective . to assess the use of cell phones and email as means of communication between pregnant women and their gynecologists and family physicians
. study design . a cross - sectional study of pregnant women at routine followup .
one hundred and twenty women participated in the study .
results .
the mean age... |
intracranial dural arteriovenous fistulas ( avfs ) constitute 1015% of intracranial vascular anomalies [ 1 , 2 ] .
avf with retrograde cortical venous drainage has a high risk of developing an aggressive clinical course with intracranial hemorrhage [ 1 , 3 ] .
hemorrhagic presentation with acute subdural hematoma (... | dural arteriovenous fistula ( avf ) presenting with subdural hematoma is relatively rare .
we report a case of dural avf presenting as acute subdural hematoma ( asdh ) and provide a review of the literature . a 56-year - old man presented with disturbance of consciousness .
computed tomography demonstrated a right ... |
data were drawn from a 2008 extract of the sci - dc dataset , a dynamic clinical database that was started on a national basis in 2000 and included retrospective data collation where available .
completeness increased up to 2004 , after which we estimate that that data were derived from all hospitals , and all except... | objectiveto describe the association of bmi with mortality in patients diagnosed with type 2 diabetes.research design and methodsusing records of 106,640 patients in scotland , we investigated the association between bmi recorded around the diagnosis of type 2 diabetes mellitus ( t2 dm ) and mortality using cox proport... |
microarray technology enables the
scientist to measure the mrna expression levels of thousands of genes
simultaneously . for a particular species of interest
, one can make microarray
measurements under many different conditions and for different types of cells
( if it is a multicellular organism ) .
gene... | we propose a bayesian procedure to cluster temporal gene expression microarray profiles ,
based on a mixed - effect smoothing - spline model , and design a gibbs sampler to sample from
the desired posterior distribution .
our method can determine the cluster number automatically
based on the bayesian informatio... |
first described by voorhoeve in 1924 , osteopathia striata ( os ) can occur in isolation or as part of a syndrome .
the disease in combination with cranial sclerosis ( cs ) was first described by hurt in 1953 .
os with cs ( os - cs ) is a rare sclerosing bone dysplasia characterized by radio - paque longitudinal st... | osteopathia striata with cranial sclerosis ( os - cs ) is characterized by linear bone dysplasia at the long bone radiographically and sclerotic change at the cranium .
the purpose of this case report is to study the symptoms and treatments of osteomyelitis in a patient with os - cs .
a 41-year - old patient had pu... |
from january 2011 through october 2011 , a total of 455 samples ( fecal , intestine , and milk ) were collected from 57 farms in 12 provinces of china .
all samples were evaluated by reverse transcription pcr ( rt - pcr ) , by using previously described primers ( 6 ) .
forty - five ( 78.95% ) of the farms had at le... | in 2011 , porcine epidemic diarrhea virus ( pedv ) infection rates rose substantially in vaccinated swine herds .
to determine the distribution profile of pedv outbreak strains , we sequenced the full - length spike gene from samples from 9 farms where animals exhibited severe diarrhea and mortality rates were high .... |
the early institution of goal - directed therapy has always been perceived as a key factor for the successful management of critically ill patients . in trauma patients , for example , the early detection of occult hypoperfusion and its correction using goal - directed therapy have been shown to reduce both mortality a... | the surviving sepsis campaign guidelines for the management of severe sepsis and septic shock recommend that the initial hemodynamic resuscitation be done according to the protocol used by rivers and colleagues in their well - known early goal - directed therapy ( egdt ) study .
however , it may well be that their pa... |
the study was approved by the ethics committee at the medical faculty of wrzburg university .
patients 194 , with nshl were recruited through the comprehensive hearing center at wrzburg university hospital .
although study participants were counselled primarily for nshl , additional symptoms were found in a limited... | increasing attention has been directed toward assessing mutational fallout of stereocilin ( strc ) , the gene underlying dfnb16 .
a major challenge is due to a closely linked pseudogene with 99.6% coding sequence identity . in 94 gjb2/gjb6-mutation negative individuals with non - syndromic sensorineural hearing loss ... |
growth hormone - secreting pituitary adenoma ( ghpa ) is a rare , chronic , systemic disease that is associated with premature death and significant morbidity.1 it is related to high levels of growth hormone ( gh ) and insulin - like growth factor - i ( igf - i ) . the standardised mortality index ( the ratio of observ... | the management of acromegaly caused by an uncommon growth hormone - secreting pituitary adenoma can be challenging in low - resource african subregion .
we conducted a study over a 2-year period to describe the results and challenges following surgical treatment of this rare condition in our centre .
the clinical o... |
semiconductor
heterostructures form the cornerstone of many electronic
and optoelectronic devices and are traditionally fabricated using
epitaxial growth techniques . more recently
, heterostructures have
also been obtained by vertical stacking of two - dimensional crystals ,
such as graphene and related tw... | |
one of the most important sight - threatening eye disorders in ophthalmology is open - angle glaucoma ( oag ) .
this progressive neurodegenerative disease leads to glaucomatous optic neuropathy and eventually , through glaucomatous visual field loss , to loss of sight .
together with age - related macular degenerat... | open - angle glaucoma ( oag ) is the commonest cause of irreversible blindness worldwide . apart from an increased intraocular pressure ( iop ) , oxidative stress and an impaired ocular blood flow
are supposed to contribute to oag .
the aim of this study was to determine whether the dietary intake of nutrients that... |
flavonoid pigments are well known to play an important role in pigmentation of tissues such as flowers , fruits , and grains .
these pigments not only render the tissues as more conspicuous but also add physiological function to tissues , such as protection against uv damage and increased level of grain dormancy . ... | flavonoid pigments are known to accumulate in red grains and coleoptiles of wheat and are synthesized through the flavonoid biosynthetic pathway .
flavanone 3-hydroxylase ( f3h ) is a key enzyme at a diverging point of the flavonoid pathway leading to production of different pigments : phlobaphene , proanthocyanidin ... |
involvement of the adrenal gland by disseminated non - hodgkin s lymphoma is found in up to 25% of patients with lymphoma on postmortem examination . in contrast , primary adrenal gland lymphoma is extremely rare and only 65 cases have been reported worldwide . in korea , the first case of a primary adrenal gland lymph... | primary adrenal lymphoma is extremely rare .
we describe a case of non - hodgkin s lymphoma of diffuse large b - cell type with right adrenal involvement . the patient received chemotherapy and external irradiation and achieved complete remission of the disease .
we describe the case of primary adrenal lymphoma wit... |
in 2002 , the laboratory lead by croce ( 2009 ) found that two non - protein - coding rna ( actually mirna ) genes , mir-15a and mir-16 - 1 , map to a region of chromosome 13 ( 13q14 ) that is frequently deleted in chronic lymphocytic leukemia ( cll ) and that mir-15a and mir-16 - 1 are indeed lost in approximately 70%... | in the last 20 years , the field of cellular and molecular oncology has been born and has moved its first steps , with an increasingly rapid pace .
hundreds of oncogenic and oncosuppressive signaling cascades have been characterized , facilitating the development of an ever more refined and variegated arsenal of diag... |
the pentagon is a form found commonly in nature , in everything from flowers to hurricanes .
it ( or rather the pentacle ) is also the shape of the path described by venus in the night sky which has led to its association with witchcraft and devilry .
aperiodic tilings in mathematics have been attracting interest a... | neuron neurotransmitter receptors are in general pentameric .
this enables them to form pentagonal components in biological quasicrystals ( similar to mathematical aperiodic tilings ) . as quasicrystals have been proposed to require quantum effects to exist this might introduce such effects as a component of neurotra... |
oral cancer is one of the most familiar forms of cancers in the indian subcontinent . from the beginning of twentieth - century ,
oral squamous cell carcinoma ( oscc ) is more commonly noted in men usually above 40 years of age and only about 0.4 to 3.9% of the patients are affected by oscc earlier than 40 years .
... | background : oral squamous cell carcinoma ( oscc ) is commonly noted in elder men , when occurring in younger individuals , its aggression and prognosis is questioned due to biased data in literature .
traditionally , various histopathological grading systems have been used for assessing aggression and prognosis of o... |
intraductal papillary neoplasm of the bile duct ( ipnb ) is a rare variant of bile duct tumors , which is characterized by papillary or villous growth within the bile duct lumen .
formerly , attention has been drawn to biliary tumors with macroscopically visible mucin secretion , which show predominantly papillary gr... | intraductal papillary neoplasm of the bile duct ( ipnb ) is a rare variant of bile duct tumors characterized by papillary growth within the bile duct lumen and is regarded as a biliary counterpart of intraductal papillary mucinous neoplasm of the pancreas .
ipnbs display a spectrum of premalignant lesion towards inva... |
world health organization ( who ) defines adolescence as the period of life between 10 and 19 years of age .
the adolescent experiences not only physical growth and change but also emotional , psychological , social , and mental change and growth .
adolescence is a period of increased risk taking and therefore susc... | aims : to identify the reproductive health issues associated with adolescence and the readiness to avail services like adolescent friendly clinic ( afc ) among urban school going children.materials and methods : a quantitative survey was carried out using a self - administered structured questionnaire among 1440 ( 748 ... |
the sample consisted of 348 ( 213 male and 135 female ) volunteering students of tehran university of medical sciences .
the age range of the total sample was 18 - 44 , having an average age of 21/85 , with standard deviation of 3/12 .
the padua inventory- washington state university revision ( pi - wsur ) ( 30 ) :... | objectivethe psychometric properties and factor structure of the persian padua inventory washington state university revision ( pi - wsur ) , a measure of obsessive- compulsive phenomena , was examined in a non - clinical sample of 348 iranian university students.methodthe pi - wsur was translated into persian , and it... |
niger state ( see figure 1 ) is a state in the north central nigeria , covering a total land mass of 76,363 km ( about 10% of nigeria 's total land mass ) and possessing an estimated population of 4,372,030 people ( 2,215,824 males and 2,156,206 females ) .
it is the largest among the 36 states and the federal capit... | nigeria 's 20092013 malaria strategic plan adopted who diagnosis and treatment guidelines , which include the use of rapid diagnostic tests ( rdts ) prior to prescribing treatment with artemisinin combination therapies ( acts ) .
the current study explores accessibility barriers to the use of rdts in niger state and ... |
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