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bullous pemphigoid ( bp ) is the most frequent autoimmune bullous disorder and is clinically characterized by tense blisters and crusts on erythematous or apparently uninvolved skin .
direct immunofluorescence ( if ) microscopy of a perilesional skin biopsy that typically reveals linear deposits of complement compone... | the use of a broad spectrum of novel detection systems for autoantibodies to the basement membrane proteins bp180 and bp230 has greatly facilitated the diagnosis of bullous pemphigoid , which most likely explains its increasing incidence in central europe . because the pathogenic relevance of antibodies to human bp180 ... |
primitive neuroectodermal tumors ( pnets ) are rare malignant neoplasms which occur predominantly in children and young adults .
pnets belong to the ewing 's sarcoma family of tumors and are associated with the same reciprocal chromosomal translocation as the ewing 's sarcoma .
pnets usually develop in the cerebell... | primary spinal primitive neuroectodermal tumors ( pnets ) are very rare conditions .
most of these tumors occur in children and young adults .
a 63-year - old man with a primary spinal pnet in the conus medullaris from the l1 to l2 level is presented in this report .
the optimal treatment of primary spinal pnets ... |
macrolides , which are primarily antibiotics , belong to the polyketide group of natural products .
they derive their name from their characteristic structural features , a macrocyclic lactone ring to which various deoxy sugars , most commonly cladinose and desosamine , are attached .
the molecular structure of the... | macrolide antibiotics possess several , beneficial , secondary properties which complement their primary antimicrobial activity .
in addition to high levels of tissue penetration , which may counteract seemingly macrolide - resistant bacterial pathogens , these agents also possess anti - inflammatory properties , unr... |
integrated cares solutions are prominent and even forced by health care policy . but how can we understand the needs of different stakeholders in this system ?
a closer look , using the structuration theory of anthony giddens , may be helpful .
as this is a matter of fact , the health care system was analyzed by th... | introductionthe health care system is in transition .
integrated cares solutions are prominent and even forced by health care policy . but how can we understand the needs of different stakeholders in this system ?
why do they still not act effectively and efficiently together ?
a closer look , using the structura... |
the united states ( us ) prevalence of autism spectrum disorder ( asd ) surged from 1 in 150 children in 2007 to 1 in 88 children in 2012 with substantial increase in immigrant minority groups including hispanic and somali children.[1 - 3 ] asd is characterized by atypical development and pervasive impairment in social... | background : the prevalence of autism spectrum disorder ( asd ) in united state ( us ) has surged from 1 in 150 children in 2007 to 1 in 88 children in 2012 with substantial increase in immigrant minority groups including hispanic and somali children .
our study objective is to examine the associations between househ... |
the prevalence of vaginal agenesis is 1 in 40005000 live female births , whereas that of cervical agenesis is 1 in 80,00010,0000 live births .
most of these patients have small rudimentary uterus without any endometrial cavity , but very rarely unilateral cornua may present with functioning endometrial cavity , with ... | the presence of cervicovaginal agenesis with unicornuate uterus is a very rare mullerian anomaly .
its true incidence is still unknown .
the presence of functioning unicornuate uterus poses a great challenge for a gynecologist because a successful repair could restore normal menses and may preserve a patient 's fer... |
today , cardiac diseases are the most common causes of mortality worldwide . they would be the main cause of death worldwide in 2020 , according to a prediction made by the world health organization ( who ) . in the middle east countries including iran
, cardiac diseases are turning into major health and social probl... | background : pain is a common phenomenon after surgery . cardiac surgeries are no exception and patients generally experience acute pain after these surgeries .
inadequate pain management after cardiac surgery predisposes patients to many complications .
therefore , the aim of this study was to determine the effect... |
vertebrobasilar stroke associated with the anterior approach to the cervical spine is rare and has not been reported in cervical disc arthroplasty surgery .
we report the case of a 60-year - old patient who underwent cervical disc arthroplasty at c4 - 5 , c5 - 6 and c6 - 7 .
postoperatively , due to symptoms and si... | backgroundvertebrobasilar stroke associated with the anterior approach to the cervical spine is rare and has not been reported in cervical disc arthroplasty surgery .
we report the case of a 60-year - old patient who underwent cervical disc arthroplasty at c4 - 5 , c5 - 6 and c6 - 7 .
postoperatively , due to sympt... |
changes in environmental conditions can have a significant impact on the development and function of the brain .
neural stem cells ( nscs ) integrate both local and systemic signals to modulate their rate and extent of proliferation to meet the needs of the organism ( kokovay et al . , 2008 ) .
these quiescent nsc... | summaryneural stem cells in the adult brain exist primarily in a quiescent state but are reactivated in response to changing physiological conditions . how do stem cells sense and respond to metabolic changes ? in the drosophila cns , quiescent neural stem cells are reactivated synchronously in response to a nutritio... |
the impact of auditory sensory deprivation in the life of an individual is enormous because it not only affects one 's ability to properly understand auditory information , but also the way people relate to their environment and their culture .
in addition , this sensory deprivation causes biological , psychological ... | introduction the impact of auditory sensory deprivation in the life of an individual is enormous because it not only affects one 's ability to properly understand auditory information , but also the way people relate to their environment and their culture .
the monitoring of adult and elderly subjects with hearing l... |
trabeculectomy as the standard procedure for the surgical management of glaucoma is widely performed in patients with glaucoma to reduce intraocular pressure ( iop ) since 1968 .
it is well known that episcleral fibrosis and subconjunctival scarring are the major causes of failure of trabeculectomy . thus , inhibit... | purpose . to evaluate the effectiveness and safety of the ologen as an aid for trabeculectomy performed for primary open - angle glaucoma compared with mitomycin c. methods . in this prospective , randomized , parallel assignment , comparative study , 31 eyes of 21 primary open - angle glaucoma patients were allocated ... |
common variable immunodeficiency disorders ( cvids ) are a heterogenous group of immune deficiencies characterized by hypogammaglobulinemia .
the diagnostic criteria are : history of recurrent infections , decreased igg levels ( less than two standard deviations below the lowest normal level ) , one more immunoglobul... | common variable immunodeficiency disorders ( cvids ) , a heterogeneous group of primary immune deficiencies , can present at all age .
our patient with a hitherto undiagnosed cvid , symptomatic since middle ages , presented with severe pneumonia .
specific management of his cvid in addition to standard therapy was ... |
d - lactic acidosis has been well documented in ruminants . in humans , however , d - lactic acidosis is very rare and usually only l - lactic acidosis is identified in clinical laboratories . in 1979 , oh et al.1 ) first described the d - lactic acidosis in short bowel syndrome that presented with neurological manifes... | d - lactic acidosis has been well documented in ruminants . in humans , d - lactic acidosis is very rare , but d - lactic acidosis may be more common than generally believed and should be looked for in a case of metabolic acidosis in which the cause of acidosis is not apparent .
the clinical presentation of d - lacti... |
brucellosis is a zoonotic disease caused by gram - negative bacteria , namely brucella spp .
humans can be infected by the ingestion of raw dairy products , the consumption of infected meat from sheep , goat , cattle , water buffalo , camel , and pig and close contact with the secretions from infected animals main sy... | backgroundour study aimed to demonstrate the frequency of the syndrome of inappropriate adh secretion ( siadh ) and associated factors during the course of brucellosis in children and adolescents.material/methodsthe study included children and adolescents aged 018 years old diagnosed with brucellosis between 2012 and 2... |
pseudoexfoliation syndrome ( pes ) is a common age - related fibrillopathy of unknown cause and is the most common clinical precursor of open - angle glaucoma ( 1 ) .
originally , pseudo - exfoliation material ( pem ) accumulation was thought to be limited to the anterior segment of the eye ; however , accumulation i... | abstractobjectives : pseudoexfoliation syndrome ( pes ) is a common age - related fibrillopathy related to accumulation of pseudoexfoliation material ( pem ) in certain places in the body , especially blood vessels . erectile dysfunction ( ed ) is another condition related to vascular pathology and in this study it is ... |
the management of dental caries is aimed to limit tooth demineralization by modifying the dietary habits , inhibiting or modifying oral microbial growth , altering the salivary ph and buffering capacity .
. they can easily colonize the tooth surface and initiate acid production by synthesizing extracellular polysacch... | aim : to compare the effect of 20% aqueous extract of terminalia chebula and emblica officinallis with chlorhexidine as an anticaries mouthwash an in vivo study.methodology:20% aqueous extract of terminalia chebula and emblica officinalis were prepared .
forty five high caries risk patients were divided into group 1... |
for pituitary down - regulation , depot gonadotropin releasing hormone agonist ( gnrha ) protocol is more convenient to use while daily low - dose protocol allows more rapid recovery of pituitary response after withdrawal and confers greater flexibility .
dosages of gnrha range from 1.88 ( half - dose ) to 3.75 mg ( ... | aim : to review the experience on depot - dose , and daily low - dose gonadotropin releasing hormone agonist ( gnrha ) long protocols and identify prognostic factors.setting and design : a chart review was conducted on 2106 depot and 1299 daily low - dose cycles at a university hospital.methods:clinical parameters were... |
neuroleptic malignant syndrome ( nms ) is a potentially life - threatening adverse reaction to antipsychotic drugs .
neuroleptic malignant syndrome is uncommon with the use of atypical antipsychotics like olanzapine . in the past few years
there has been increased use of atypical antipsychotic drugs . a case of nms... | an 18 year old male diagnosed as a case of bipolar affective disorder ( bpad ) , developed neuroleptic malignant syndrome ( nms ) following treatment with olanzapine ( 20 mg per day ) , an atypical antipsychotic drug .
nms is usually seen with typical antipsychotic drugs .
the patient was diagnosed as a case of nms... |
the interface between nanomaterials and
biomolecules initiates
comprehension of a new science concerned with the innocuous use of
nanotechnology and nanomaterials for nano bio
applications .
the dynamic forces and
molecular components modeling these interactions must be understood
for better study of t... | with the advent of nanobiotechnology ,
there will be an increase
in the interaction between engineered nanomaterials and biomolecules .
nanoconjugates with cells , organelles , and intracellular structures
containing dna , rna , and proteins establish sequences of nano
bio
boundaries that depend on several ... |
we used an updated version of the hiv synthesis transmission model , an individual - based stochastic model of hiv transmission and infection progression and treatment among heterosexuals that has been previously described [ 1113 ] .
the model includes an age structure , and sexual risk behavior is modeled as the num... | backgroundstudies have demonstrated that self - testing for human immunodeficiency virus ( hiv ) is highly acceptable among individuals and could allow cost savings , compared with provider - delivered hiv testing and counseling ( phtc ) , although the longer - term population - level effects are uncertain .
we evalu... |
traumatic brain injuries ( tbi ) occur when sudden trauma damages the brain and disrupts its normal function .
it can cause significant disability and mortality and represents a public health concern in both developed and developing countries . besides the physical effects , tbi can also have profound and lasting psy... | most cranio - cerebral injuries seen in the emergency department are caused by acceleration - deceleration or a direct impact mechanism .
compression or crush injury to the head is less commonly seen .
a crush injury occurs when a body part is subjected a degree of force or pressure , usually after being trapped be... |
a couple that is unable to get pregnant after one year of unprotected intercourse , usually ends up at the gynaecology department of a hospital .
therefore the man has to collect his semen in a special container and deliver it within one hour of collection to the hospital .
the parameters usually determined with a ... | the gold standard of semen analysis is still an manual method , which is time - consuming , labour intensive and needs thorough quality control .
microfluidics can also offer advantages for this application .
therefore a first step in the development of a microfluidic chip has been made , which enables the man the ... |
acetabular fractures after high - energy trauma are serious and uncommon orthopedic injuries that can have late complications , such as posttraumatic arthritis and avascular necrosis of the femoral head .
total hip arthroplasty ( tha ) is an effective surgical option to relieve pain and restore function after failed ... | background : porous - coated cups have been widely used in acetabular reconstruction after failed treatment of acetabular fractures , and good results have been reported with the use of these cups ; however , the durability and functionality of modular trabecular metal ( tm ) acetabular components in acetabular reconst... |
substance abuse and dependence , especially opioid dependence , contribute significantly to the global burden of disease in greece . according to the greek documentation and monitoring centre for drugs ( ektepn ) a rising trend in the use of all illegal drugs
was observed during the last 30 years in greece among 1519... | 130 patients from a methadone maintenance treatment program agreed to complete symptoms checklist 90-revised ( scl-90r ) and alcohol use disorders identification test ( audit ) self - report scales .
scores higher than the proposed cut - score on scl-90r scale were observed on depression , obsessions - compulsions , ... |
it has been generally accepted that chronic inflammation may increase the risk of cancer by providing bioactive molecules from the tumor microenvironment , including cytokines and growth factors that promote continuous cell proliferation and malignant transformation .
interleukin-6 ( il-6 ) is a member of the il-6-ty... | the recent jak1/2 inhibitor trial in myeloproliferative neoplasms ( mpns ) showed that reducing inflammation can be more beneficial than targeting gene mutants .
we evaluated the proinflammatory il-6 cytokine and jak - stat signaling pathway related genes in circulating cd34 + cells of mpns . regarding laboratory dat... |
epstein - barr virus ( ebv ) is involved in numerous lymphoproliferative diseases .
in addition to classical lesions such as endemic burkitt 's lymphoma and infectious mononucleosis , there are other disorders of the lymphoid system that are discussed in relation to ebv : b - cell lymphomas in immunosuppressed indivi... | |
with the worldwide distribution of gamma knife units and linac surgery systems , considerable amounts of clinical data on single - fraction radiosurgery are now available [ 1 , 2 ] . on the other hand ,
hypofractionated stereotactic radiotherapy is attracting more attention owing to its efficacy and lower toxicity [ ... | we investigated the applicability of the repairable - conditionally repairable ( rcr ) model and the multi - target ( mt ) model to dose conversion in high - dose - per - fraction radiotherapy in comparison with the linear - quadratic ( lq ) model .
cell survival data of v79 and emt6 single cells receiving single dos... |
mdscs are immature myeloid cells that fail to terminally differentiate into granulocytes , macrophages or dendritic cells ( dcs ) upon chronic inflammatory conditions and exhibit immunosuppressive functions by multiple mechanisms 1 - 4 .
these cells are very heterogeneous and therefore their phenotypical characterist... | tumor progression is often associated with chronic inflammation in the tumor microenvironment , which is mediated by numerous cytokines , chemokines and growth factors produced by cancer and stroma cells .
all these mediators support tumor development and immunosuppression in autocrine and/or paracrine ways .
neutr... |
about 95% of patients with tuberculosis ( tb ) and 70% of patients with diabetes mellitus ( dm ) live in the low and middle income countries .
the epidemic growth of dm has occurred in developing countries where tb is highly endemic . as a result , dm and
tb are increasingly present together , and this calls for re... | background : diabetes and tuberculosis often present together and complicate each other at many levels .
a collaborative framework for care and control of diabetes and tuberculosis developed by world health organisation and international union against tuberculosis and lung diseases emphasizes routine bi - directional... |
it is caused by the obligate intracellular parasite toxoplasma gondii.1 the typical presentation of ocular toxoplasmosis is characterized by focal retinochoroiditis adjacent to pigmented chorioretinal scar and vitreous inflammation.2 in addition to the typical presentation of this disease , atypical forms of ocular tox... | a 24-year - old healthy male presented with a chief complaint of blurred vision in the right eye for 1-week .
fundus examination indicated right exudative retinal detachment and choroidal ischemia .
the patient responded well to anti - toxoplasmosis medications and steroids .
exudative retinal detachment and chor... |
giant cell arteritis ( gca ) , also known as temporal arteritis or horton s arteritis , is an inflammation t - lymphocyte mediated inflammation affecting the internal elastic lamina and external arteries of large and medium size.1 it is a medical emergency that can result in severe systemic and ocular complications . a... | this article describes the case of a 68-year - old patient suffering from giant cell arteritis ( also known as horton s arteritis or temporal arteritis ) .
the patient came to our attention due to a large and sudden visual loss caused by the occlusion of major retinal arteries .
the patient had neuralgic pain in th... |
ureteropelvic junction ( upj ) obstruction is a condition where urine flow and transport from the kidney to the upper ureter is impaired , due to a variety of causes ( intrinsic obstruction
several management options are available for this problem , including open surgery ( op ) , antegrade and retrograde endourologi... | objectives : the benefits of laparoscopic surgery with robotic assistance ( da vinci robotic surgical system , intuitive surgical , sunnyvale , ca ) includes elimination of tremor , motion scaling , 3d laparoscopic vision , and instruments with 7 degrees of freedom . the benefit of robotic assistance could be most pron... |
body - mass index ( bmi ) , an important indicator of obesity prevalence in large populations , generally reflects degree of fatness among individuals .
accurate determination of obesity has become exceedingly important because of major health threats posed by excess adiposity .
obesity is associated with increased... | obesity prevalence and average body composition vary by us race and gender .
asian americans have the lowest prevalence of obesity .
relying on body - mass index ( bmi ) to estimate obesity prevalence may misclassify subgroups that appear normally weighted but have excess body fat .
we evaluated percentage body f... |
the responsibility of physicians is outstanding in proportion to the respect and honour paid to them by the society . in other words ,
when a person proudly wears the white coat , the society sees itself bound to treat him / her with great respect and he / she , too , sees her / himself bound to observe specific dign... | one of the most important occupational tensions a physician encounters in his / her practice is the complaints lodged against him / her by the patients . the purpose of this study is examining the complaints against physicians and dentists entering the medical council organization of tehran in the years ending on 20 ma... |
2003 ] , are nuclear receptor coactivators that lack histone acetyltransferase ( hat ) or methyltransferase activity .
these proteins are members of the group iii lim domain containing family of proteins , which are characterized by their localization to both focal adhesions and within the nucleus [ dawid et al . ,
... | in recent years , numerous nuclear receptor - interacting proteins have been identified that influence nuclear transcription through their direct modification of chromatin . along with coactivators that possess histone acetyltransferase ( hat ) or methyltransferase activity , other coactivators that lack recognizable... |
this article emerges from a research project entitled an investigation of postoperative analgesic efficacy following shoulder surgery and its relationship to hospital length of stay which took place in 2010 in victoria , australia .
the methods used were an in - person survey questionnaire , semistructured intervie... | backgroundthe paper reports on the importance of the interpersonal nexus within qualitative research processes , from a recent research project on patient experiences of shoulder surgery .
our aim is to reveal the importance of qualitative research processes and specifically the role of the interpersonal nexus in gen... |
diabetic nephropathy is a life - threatening complication that occurs in 2040% of patients suffering from diabetes and is the leading cause of chronic kidney disease .
there are many factors influencing the development of diabetic nephropathy , including genetic , environmental , hemodynamic , and metabolic factors .... | objective .
diabetic nephropathy is a life - threatening complication in patients with long - standing diabetes .
hemodynamic , inflammatory , and metabolic factors are considered as developmental factors for diabetic nephropathy . in this study , we evaluated whether pharmacological interventions with salicylate ,... |
perinatal asphyxia is defined as the interference of gas exchange or blood flow to and from the fetus in the perinatal age.1 this interruption could be extended to partial asphyxia and sudden subtotal asphyxia because of a sentry experience or a combination of both.2 hypoxic - ischemic injuries to the brain might be th... | perinatal hypoxic - ischemic encephalopathy ( hie ) affects one to three per 1,000 live full - term births and can lead to severe and permanent neuropsychological sequelae , such as cerebral palsy , epilepsy , mental retardation , and visual motor or visual perceptive dysfunction .
melatonin has begun to be contempla... |
preservatives are deliberately added to food products in order to stop or delay unwanted microbiological , enzymatic or chemical changes within the extension of the product shelf life .
sodium benzoate , potassium sorbate and natamycin are generally used to control mold , inhibit yeast growth and some bacteria ( 1 ) ... | background : regarding the public health concerns over the use of food preservatives in yoghurt drink doogh , the aim of this study was the determination of sodium benzoate , potassium sorbate and natamycin in doogh . based on iranian national standard
, none of these preservatives are permitted to be used in doogh... |
dextrocardia is a rare condition that is usually found incidentally and in association with other congenital abnormalities .
the incidence of dextrocardia has been reported to be less than 1% and a recent study found the incidence to be only 0.22% .
patients with diaphragmatic hernia have variant symptoms and signs... | abstractdiaphragmatic injury is an uncommon traumatic injury ( < 1% ) .
although most diaphragmatic injuries can be obvious ( eg , herniation of abdominal contents on chest radiograph ) , some injuries may be subtle and imaging studies can be nondiagnostic in many situations .
patients with diaphragmatic hernia eit... |
hair and wool fibres typically consist of three major structural components : the cuticle , the cortex and the central medulla .
approximately 90% of the cortical cells contain longitudinally arrayed keratin intermediate filaments ( ifs ) , consisting of keratin ( k ) proteins .
these filaments have a matrix surrou... | most protein in hair and wool is of two broad types : keratin intermediate filament - forming proteins ( commonly known as keratins ) and keratin - associated proteins ( kaps ) .
keratin nomenclature was reviewed in 2006 , but the kap nomenclature has not been revised since 1993 .
recently there has been an increas... |
a 45year old male patient with recurrent symptomatic documented supraventricular tachycardia for the last 8 years was referred to our department for an electrophysiological ( ep ) study .
the ecg during the symptoms showed a narrow qrs complex tachycardia at 180 beats / min ( bpm ) .
an arterial hypertension and a ... | key clinical messagea patient developed a transient firstdegree av block during a radiofrequency ablation of an atrioventricular nodal reentrant tachycardia .
three days later the patient presented with a thirddegree av block .
it resolved within 24 h under antiphlogistic therapy .
patient was asymptomatic withou... |
knowledge and use of plants as herbal medicines has occurred in various populations throughout human evolution , beginning when man was learning to select plants for food , and to relieve ailments and diseases.1 however , during the second half of the twentieth century , especially in the western world , herbal medicin... | herbal medicines have been widely used around the world since ancient times .
the advancement of phytochemical and phytopharmacological sciences has enabled elucidation of the composition and biological activities of several medicinal plant products .
the effectiveness of many species of medicinal plants depends on... |
the university of pittsburgh institutional review board approved in advance both receipt of , and work with , human islets .
the cyclin d family includes three d - cyclins , shown schematically in supplementary fig .
3 ( available in an online appendix ) , mrna encoding each of the three d - cyclins is present in h... | objectivemost knowledge on human -cell cycle control derives from immunoblots of whole human islets , mixtures of -cells and non--cells .
we explored the presence , subcellular localization , and function of five early g1/s phase molecules
cyclins d13 and cdk 4 and 6in the adult human -cell.research design and meth... |
faun tail nevus is a posterior midline cutaneous marker for underlying spinal abnormalities like spinal dysraphism .
failure of the caudal neuropore to close at the end of fourth week of intrauterine life results in neural tube defects like spinal dysraphism which may also involve tissues overlying the spinal cord . ... | faun tail nevus is a posterior midline cutaneous lesion of importance to dermatologists as it could be a cutaneous marker for its underlying spine and spinal cord anomaly .
we report a 13-year - old girl with excessive hair growth over the lumbosacral region since birth .
there was associated spinal anomaly with no... |
the effective use of library plays an important role in users ability in identification , retrieval and accessing of information .
therefore today libraries are considered the foundation of education , research and development and effective use of academic libraries can greatly affect the quality of education and res... | introduction : the efficient use of libraries can be an important factor in determining the educational quality of universities . therefore , investigation and identification of factors affecting library anxiety becomes increasingly necessary .
the purpose of this research is to determine the factors effecting librar... |
lead halide perovskites
( ch3nh3pbx3 , where x = i , br ) and
other metal halide complexes ( mxn , where
m = pb , cd , in , zn , fe , bi , sb ) have been
studied as inorganic capping ligands for colloidal nanocrystals .
we
present the methodology for the surface functionalization via ligand - exchange
rea... | |
over the past decades type-2 diabetes mellitus ( dm ) has become a major public health concern .
the world health organization estimates that worldwide 220 million people have diabetes , a number that may double by the year 2030 .
diabetic patients have a higher prevalence of coronary heart disease and are more lik... | purposeto compare the coronary atherosclerotic burden in patients with and without type-2 diabetes using ct coronary angiography ( ctca).methods and materials147 diabetic ( mean age : 65 10 years ; male : 89 ) and 979 nondiabetic patients ( mean age : 61 13 years ; male : 567 ) without a history of coronary art... |
previous studies have shown that low - load , low - intensity , restricted blood flow , resistance ( kaatsu ) exercises increase muscle strength and induce muscle hypertrophy at relatively small , 20% - 30% of the 1-repetition maximum ( 1-rm ) , loads in subjects in healthy sedentary subjects and athletes , as well as ... | objectives : exercise with partially restricted blood flow is a low - load , low - intensity resistance training regimen which may have the potential to increase muscle strength in the obese , elderly and frail who are unable to do high - load training . restricted blood flow exercise has also been shown to affect bloo... |
curvularia species are dematiaceous fungi known to cause nondermatophytic onychomycosis , phaeohyphomycosis , and disseminated infections in immunocompromised patients . diagnosed by culture and microscopy in repeated sessions .
curvularia can be microscopically distinguished from other dematiaceous fungi due to the ... | a 57 year healthy farmer with congenital nail pterygium presented with a verrucous growth on nail bed since 8 months .
he was not diabetic and hiv rapid card test negative .
our clinical diagnosis was chromoblastomycosis but culture showed growth of curvularia species on two occasions and histopathology showed hyph... |
in
recent years , the emergence of drug - resistant pathogens has
led to treatment failures for many infectious diseases , such as malaria .
resistance to current antimalarials is a major problem , e.g. , chloroquine ,
sulfadoxine - pyrimethamine , and in some areas , mefloquine . to reduce the spread of resist... | in
the pursuit of new antimalarial leads , a phenotypic screening
of various commercially sourced compound libraries was undertaken
by the world health organisation programme for research and training
in tropical diseases ( who - tdr ) .
we report here the detailed characterization
of one of the hits from t... |
chronic biting of oral mucosa or morsicato mucosae oris is a form of factitial / unintentional injury that is observed commonly on the buccal and labial mucosa and lateral surface of tongue .
habitual lip or cheek biting usually occurs as an unconscious psychogenic habit caused by a wide range of emotions .
this mi... | chronic biting of oral mucosa is an innocuous self inflicted injury , commonly seen in children suffering from developmental and psychological problems and has rarely been reported in normal unaffected individuals .
the management strategies vary from counseling , prescription of sedatives to different prosthetic shi... |
the health of a community depends extensively on the health of mothers and children . in this regards , non - complicated pregnancies play an important role in the birth of a healthy infant .
it has been shown that the number of women addicted to opiates is on the rise and this issue is increasingly alarming in pregn... | background : opium is one of the most commonly abused opiates in developing countries including iran . considering the importance of maternal health on the newborn
, we aimed to assess the effect of opium abuse on fetal heart rate ( fhr ) characteristics in a sample of pregnant women in zahedan , southeast iran.metho... |
plants which more than 100 000
low molecular secondary
metabolites have been discovered , with the estimated total number
in plants exceeding 500 000 .
plant metabolites not only are used
for food purposes but also serve as an
important historical source of medicines .
plant cell - based
bioproces... | plant cells and tissue cultures hold
great promise for controlled production of a myriad
of useful secondary metabolites on demand .
the
current yield and productivity can not fulfill the
commercial goal of a plant cell - based bioprocess for
the production of most secondary metabolites . in
order to stre... |
infection with hepatitis b virus ( hbv ) persists as a worldwide public health problem , with vertical transmission of hbv being responsible for approximately one third of all new cases of hepatitis b. childhood hepatitis b immunisation has significantly reduced the incidence and prevalence of hbv infection , and curre... | a range of schedules are recommended for hepatitis b vaccination of premature infants .
this open - label study ( 217744/083 ) compared the immune response of premature ( n = 94 ) and full - term infants ( n = 92 ) to hepatitis b antigen following primary administration of hexavalent dtpa - hbv - ipv / hib vaccine at... |
the acetylation of lysine residues is an important secondary modification that regulates protein function and is controlled by the action of acetylase and deacetylase enzymes .
class i histone deacetylases ( hdacs ) are recruited to , and activated by , cognate corepressor proteins that target hdac activity to partic... | summaryclass i histone deacetylases ( hdac1 , hdac2 , and hdac3 ) are recruited by cognate corepressor proteins into specific transcriptional repression complexes that target hdac activity to chromatin resulting in chromatin condensation and transcriptional silencing .
we previously reported the structure of hdac3 in... |
while the determinants of health outcomes are complex and diverse , much of the morbidity and mortality burden associated with such diseases are preventable ; tobacco smoking is one of the most important contributors to mortality and morbidity in several diseases ( 1 ) . as the life expectancy improves in developing co... | background : smoking among the youth is an important public health concern . although several studies have investigated the correlates of smoking behavior , no theory - based study has particularly assessed this problem among medical students.objectives:this study aimed to evaluate the efficacy of the extended theory o... |
this was a retrospective study . among 412 patients who underwent surgical cuff repair for full - thickness rotator cuff tears confirmed by arthroscopic findings at the authors ' institution between january 2005 and july 2008
, 191 patients who underwent both preoperative mri and postoperative mdct at least one year ... | backgroundatrophy of rotator cuff muscles has been considered an irreversible phenomenon .
the purpose of this study is to evaluate whether atrophy is truly irreversible after rotator cuff repair.methodswe measured supraspinatus muscle atrophy of 191 patients with full - thickness rotator cuff tears on preoperative m... |
melting points were determined in open capillary tubes on a boetius melting point apparatus and are uncorrected .
the h , c nmr , cosy , noesy , hsqc , hmbc spectra were recorded on a bruker ascend 600 spectrometer at 600 mhz in deuteriochloroform with tetramethylsilane as the internal standard .
electron impact m... | new phenothiazine derivatives as 10-substituted dipyridothiazines of the 1,6-diazaphenothiazine structure were obtained in the cyclization reaction of 3-amino-3-nitro-2,2-dipyridinyl sulfide and 3,3-dinitro-2,2-dipyridinyl disulfide , and in the reaction of 2-chloro-3-ntropyridine with sodium 3-amino-2-pyridinethiolate... |
self - expandable metal stents ( sems ) for the treatment of biliary obstruction have been developed by many investigators and medical device companies for several decades since the biliary sems were introduced in 1989 .
consequently , many different sems with good performance have now become available in the clinica... | biliary self - expandable metal stents ( sems ) , a group of non - vascular stents , have been used in the palliative management of biliary obstruction around the world . however , there are still unmet needs in the clinical application of biliary sems
. comprehensive understanding of the sems is required to resolve ... |
nanopores have emerged
to become an important tool in biophysics
and single molecule sensing .
the simple detection principle of nanopore
sensing is that an analyte modulates the ionic current as it binds
or translocates an isolated nanopore . in this paper
biological
pores used for nanopore sensing have ... | nanopores
are a versatile technique for the detection and characterization
of single molecules in solution .
an ongoing challenge in the field
is to find methods to selectively detect specific biomolecules . in
this work
we describe a new technique for sensing specific proteins
using unmodified solid - st... |
the american cancer society estimates that 76,100 new cases of melanoma will be diagnosed in the usa and 9710 people are expected to die of metastatic disease .
malignant melanoma ( mm ) has various risk factors ; historically , recurrent severe sun exposure , however environmental and genetic influences also affect ... | background : the diagnosis of malignant melanoma ( mm ) is among the diagnostic challenges pathologists encounter on a routine basis .
melanoma may arise in patients with preexisting dysplastic nevi ( dn ) and it is still the cause of 1.7% of all cancer - related deaths .
melanomas often have overlapping histologic... |
emerging data suggest that type 2 diabetes is associated with an increased risk of cancer ( 13 ) .
several studies found an inverse association of serum hdl cholesterol ( hdl - c ) with cancer risk in the general population ( 49 ) , but few assessed this association among patients with type 2 diabetes , although diab... | objectiveto investigate the relationship between hdl cholesterol ( hdl - c ) and cancer risk among type 2 diabetic patients.research design and methodswe performed a retrospective cohort study of 14,169 men and 23,176 women with type 2 diabetes .
cox proportional hazards regression models were used to estimate the as... |
bacterial strains and dna samples : a total of 296
brucella strains were included : 22 brucella reference
strains ; 110 mongolian isolates ( 16 b. abortus and 94 b.
melitensis ) ; 156 korean isolates ( 84 b. abortus and 72
b. canis ) ; and 8 non - brucella strains reported to be
serologically cross - reactive... | to diagnose brucellosis effectively , many genus- and species - specific detection methods
based on pcr have been developed . with conventional pcr assays , real - time pcr techniques
have been developed as rapid diagnostic tools . among them , real - time pcr using
hybridization probe ( hybprobe ) has been recom... |
chloramphenicol is a broad spectrum antibiotic that gained popularity in the late 1940s for ophthalmic and systemic infections including upper respiratory infections , acne , and bronchitis .
beginning in the 1950s , landmark case reports demonstrated a possible relationship between chloramphenicol and aplastic anemi... | even with its broad spectrum and low cost , concern over chloramphenicol 's adverse effects limited its use in the united states during the 1980s .
reports from united kingdom and china in the 1990s demonstrated a low incidence of blood dyscrasias with the topical preparation of chloramphenicol , and showed continued... |
1 ) general methods , 2 ) preparation , 3 ) monitoring of the ldopatodopamine conversion and subsequent dopamine oxidation , and 4 ) phantom mrs are included in the supporting information .
as a service to our authors and readers , this journal provides supporting information supplied by the authors .
such mate... | abstractin an attempt to monitor mlevel trace constituents , we applied here 1h{13c15n } tripleresonance nuclear magnetic resonance ( nmr ) to 13c/15nenriched ldopa as the inevitable precursor of the neurotransmitter dopamine in the brain . the perfect selectivity ( to render endogenous components silent ) and mlevel s... |
il succo rappresenta il principale prodotto della trasformazione industriale delle mele ( pompei , 2005 ) .
alimento ricco di antiossidanti , ferro e vitamina c , povero di sodio e grasso apprezzato e consumato da persone di tutte le et ( lee et al . , 2003 ; leontowicz et al . ,
secondo dati riportati da mark up ... | apple juice , for its sensory and nutritional qualities , is consumed by people of all ages .
apples are an excellent source of several phenolic compounds and the presence of polyphenols is recognized for their health promoting antioxidant properties .
thermal pasteurization of fruit juices is the conventional meth... |
glufosinate ammonium is one of the most widely used herbicides , which acts by inhibiting the synthesis of glutamine in plants ( 1 ) . given the differences in biochemical pathways and metabolism between plants and mammals , glufosinate ammonium formulations have been regarded as minimally toxic to humans and as safe p... | although glufosinate ammonium herbicides are considered safe when used properly , ingestion of the undiluted form can cause grave outcomes .
recently , we treated a 34-yr - old man who ingested glufosinate ammonium herbicide .
in the course of treatment , the patient developed apnea , mental deterioration , and six... |
coronary artery diseases ( cads ) , which have been consistently ranked among the most common cardiovascular diseases ( cvds ) , are the leading cause of mortality and morbidity in both developed and developing countries .
cads account for 21% of mortality and morbidity worldwide in both men and women . in iran , als... | background : adherence to dietary and medication regimen plays an important role in successful treatment and reduces the negative complications and severity of the disease . therefore , the present study aimed to investigate the effect of nurse - led telephone follow - up on the level of adherence to dietary and medica... |
perianal paget 's disease ( ppd ) is a variant of extramammary paget 's disease ( empd ) and represents a rare intraepidermal adenocarcinoma characterized by the presence of typical paget 's cells , appearing as large rounded vacuolated cells .
underlying associated colorectal adenocarcinoma is a frequent comorbidity... | perianal paget 's disease ( ppd ) represents a skin neoplasm which can be either primary or secondary to carcinoma from an adjacent internal organ .
ppd with underlying colorectal adenocarcinoma is usually looked upon as a secondary disease .
we report a rare case of co - associated ppd and anorectal adenocarcinoma... |
the study was reviewed and determined to be exempt from further review by the university of north carolina at chapel hill institutional review board .
the study protocol was registered in the european network of centres for pharmacoepidemiology and pharmacovigilance ( encepp ) electronic register of studies ( http://... | objectiveto add to the evidence on comparative long - term effects of insulin analog glargine versus human nph insulin on the risk for cancer.research design and methodswe identified cohorts of initiators of glargine and human nph without an insulin prescription during the prior 19 months among patients covered by the ... |
since the appearance of the first cases of contamination by the hiv virus , in the 1980s , there has been a continuous and progressive increase in the number of infected patients .
currently , much is known about the etiology and pathogenesis of this infection , which allows increasingly accurate diagnoses in early s... | the purpose of this study was to evaluate the prevalence of oral lesions in hiv - positive patients attending the specialized service for infectious - contagious diseases and parasitoses of the health secretariat of the state of par ( ure - dipe / sespa ) , in the city of belm , pa , brazil .
a total of 79 hiv - posi... |
the first month of life is a critical period in an infant 's life as its major adaptation to extrauterine life occurs .
prevalence of premature births has increased by 21% from 1990 in developed countries . in iran , a cross - sectional study in yasouj estimated the incidence of prematurity and low birth weight as 4 ... | background : continuous high - intensity noise in the neonatal intensive care unit ( nicu ) is stressful for premature infants and its reduction is considered as a nursing care .
this study aimed to evaluate the effects of earmuffs use on the physiologic and motor responses of premature infants.materials and methods ... |
proximal surface of the upper end of tibia , tibial plateau , bears a slope directed posteriorly and inferiorly relative to the long axis of the middle of the shaft .
the slope varies widely.123 it may vary with age,4 squatting habit,5 between sexes,26 or there may be no sexual dimorphism.78 slope of medial and later... | background : upper surface of the proximal tibial end , tibial plateau , has a slope directed posteroinferiorly relative to the long axis of the middle of the shaft .
it has important consideration in surgeries such as knee arthroplasty , high tibial osteotomy , and medical imaging of the knee joint .
the aim of th... |
we extracted all available records of gih events in persons who were > 65 years of age and resided in milwaukee county , wisconsin , from the hcfa database for the 480-day period from january 1 , 1992 , through april 24 , 1993 .
the dataset included age , zip code , type of admission , and international classificatio... | we used the temporal exposure response surfaces modeling technique to examine the association between gastroenteritis - related emergency room visits and hospitalizations in the elderly and drinking water turbidity before and during the 1993 milwaukee waterborne cryptosporidium outbreak .
before the outbreak , the ra... |
there is no known etiological or genetic basis for this association , and this association has not been reported before .
the severity of constipation increased with age , and he was started on daily enema and rectal washes 6 months back . he was also diagnosed to have rickets for which the treatment was initiated by... | the case of a 3-year - old boy diagnosed to have hirschsprung 's disease with infantile nephropathic cystinosis is being reported .
both these conditions are etiologically and genetically different as per current understanding and available information .
the association is incidental and has not reported before in ... |
approximately hh st25 11 of chick development the densely packed mesenchymal cells of the pre - chondrogenic y - shaped aggregate begin to differentiate and give rise to chondrocytes , the functional unit of cartilage .
type ii collagen immunolocalization in the newly differentiating y - shaped aggregate confirms tha... | the extracellular matrix ( ecm ) plays a critical role in governing cell behavior and phenotype during limb skeletogenesis .
chondroitin sulfate proteoglycans ( cspgs ) are highly expressed in the ecm of precartilage mesenchymal condensations and are important to limb chondrogenesis and cartilage structure , but litt... |
a cirurgia torcica vdeo - assistida ( ctva ) tem sido uma interveno de escolha
para o tratamento de pneumotrax espontneo ( ps ) com bolha pulmonar .
nosso
objetivo foi apresentar uma abordagem de ctva uniportal unilateral para bulectomia
bilateral e avaliar sua eficcia teraputica .
entre maio de 2011 e janeir... | objective : video - assisted thoracoscopic surgery ( vats ) has been a surgical intervention of
choice for the treatment of spontaneous pneumothorax ( sp ) with lung bulla . our
objective was to introduce a uniportal vats approach for simultaneous bilateral
bullectomy and to evaluate its therapeutic efficacy .
... |
s2 cells were cultured according to standard protocols in schneider 's media supplemented with 10% fetal bovine serum and 0.1 mg / ml penicillin / streptomycin ( lonza ) , transfected using effectene reagent ( qiagen ) and incubated for 2 d at 25 c .
pbi - uas - nwk - f - bar - egfp , peb1:eb1-gfp , and pmt - mcher... | f - bar domains form crescent - shaped dimers that bind to and deform lipid bilayers , and play a role in many cellular processes requiring membrane remodeling , including endocytosis and cell morphogenesis .
nervous wreck ( nwk ) encodes an f - bar / sh3 protein that regulates synapse growth in drosophila . unlike c... |
with technological advances in phacoemulsification instruments , emulsification and aspiration of the crystalline lens through even smaller incisions are now possible [ 16 ] .
information such as the amount of ultrasound generated by the instrument and the vacuum level achieved can be presented on the intraoperative ... | purpose .
this study retrospectively analyzed cataract surgeries to examine the usefulness of surgical media center ( smc ) ( abbott medical optics inc . ) , a new cataract surgery recording device , for training of cataract surgery .
methods .
we studied five hundred cataract surgeries conducted with a phacoemul... |
the importance of the intestinal mucosa in the inflammatory and metabolic responses to sepsis , trauma , and other critical illnesses is increasingly recognized .
major trauma and shock may initiate a cascade of
intestinal events such as intestinal cytokine overproduction , increased
intestinal permeability , and... | we have previously shown that traumatic brain injury ( tbi ) can induce an upregulation of nuclear factor kappa b ( nf-b ) and proinflammatory cytokines in the gut , which play an important role in the pathogenesis of acute gut mucosal injury mediated by inflammation . in this work
, we investigated whether progester... |
spondylo costal dysostosis ( scd ) is a rare genetic skeletal disorder characterized clinically by short trunk dwarfism , chest wall deformity and scoliosis , and radiographically by multiple segmentation defects of the vertebrae and asymmetric rib malformation ( rib fusion , misalignment and/or abnormal rib number ) .... | spondylo costal dysostosis ( scd ) is a genetic skeletal disorder characterized by a variety of costo - vertebral malformations .
scd with type i split cord malformation ( scm ) have been reported in the literature .
we report an unusual association of scd with type ii scm .
imaging studies revealed multiple vert... |
the nevoid basal cell carcinoma syndrome , first delineated by gorlin goltz ( 1960 ) is characterized by bcc , odontogenic keratocysts ( okc ) , palmar , plantar pits , ectopic calcification of falx cerebri .
75% of patients affected by nbccs show multiple bilateral keratocysts . mainly located in premolar area , may... | nevoid basal cell carcinoma syndrome is a syndrome with wide variety of manifestations ranging from oral lesions to skeletal deformities .
it calls for due responsibility of maxillofacial surgeon to diagnose the syndrome because very often they are the first health professionals to see the patient for the treatment o... |
the main goal of a successful transplant is to promote immune tolerance of the transplanted organ or tissue , allowing the reestablishment of normal physiological functions , without generating damage to the recipient or to the transplanted tissue .
the concept of tolerance in transplantation is understood as a state... | dendritic cells ( dcs ) , the most important professional antigen - presenting cells ( apc ) , play crucial role in both immunity and tolerance .
it is well known that dcs are able to mount immune responses against foreign antigens and simultaneously tolerate self - antigens .
since dcs can be modulated depending o... |
cisplatin ( cis - diammine - dichlorido - platinum(ii ) ) was established as drug against diverse tumor types including testicular , ovarian , head and neck , bladder , esophageal , and small cell lung cancer ( sclc ) [ 1 , 2 ] . however , cisplatin exhibits only limited activity against tumors like colon and breast ca... | platinum(iv ) compounds like oxoplatin ( cis , cis , trans - diammine - dichlorido - dihydroxido - platinum(iv ) ) show increased stability and therefore can be applied orally . in a panel of 38 human cancer cell lines this drug induced s - phase arrest and cell death with ic50 values 2.5-fold higher than cisplatin .
... |
the identification of the genes , their corresponding proteins and the concomitant protein networks mediating successfully between two species and resulting in either disease or symbiosis remains critical to contemporary research ( 14 ) .
while genome - wide expression - profiling approaches have been applied to succ... | the identification of the genes that participate at the biological interface of two species remains critical to our understanding of the mechanisms of disease resistance , disease susceptibility and symbiosis .
the sequencing of complementary dna ( cdna ) libraries prepared from the biological interface between two o... |
insect symbionts have been broadly categorized into two main types : primary ( p ) and secondary ( s ) symbionts .
p symbionts are mostly found within specialized structures called bacteriomes that contain bacteriocytes ( or mycetocytes ) cells within which the symbiotic bacteria are enclosed .
bacteriomes are loca... | summaryinsects form an extremely large group of animals and bear a consequently large variety of associated microbes .
this microbiota includes very specific and obligate symbionts that provide essential functions to the host , and facultative partners that are not necessarily required for survival .
the tephritida... |
systemic lupus erythematosus ( sle ) has long been characterized as a disease associated with the overexpression of proinflammatory cytokines . the early studies focused on proinflammatory genes and identified increased serum levels of tnf , il-6 , ifn , and il-10 [ 16 ] .
when cells have been examined directl... | monocytes in sle have been described as having aberrant behavior in a number of assays .
we examined gene expression and used a genome - wide approach to study the posttranslational histone mark , h4 acetylation , to examine epigenetic changes in sle monocytes .
we compared sle monocyte gene expression and h4 acety... |
happy mapping , the analysis of approximately haploid dna samples using the polymerase chain reaction , is a genome mapping method based on random dna breakage and determination of linkage 1 - 2 .
this approach is essentially analogous to classical linkage mapping , but the chromosome breakage and segregation are gen... | happy mapping was designed to pursue the analysis of approximately random haploid dna breakage samples using the polymerase chain reaction for mapping genomes . in the present study
, we improved the method and integrated two other molecular techniques into the process : whole genome amplification and the sequenom sn... |
in order to determine the optimal working distance between the magnet and the cell culture for the improvement of transfection efficiency in nci - h292 cells , magnet arrays were rearranged in the following format : in column 1 , magnet discs were positioned 3 mm beneath the cell surface of the 96-well plate .
follow... | the objective of this work was to examine the effects of magnet distance ( and by proxy , field strength ) on nanomagnetic transfection efficiency.methodsnon-viral magnetic nanoparticle - based transfection was evaluated using both static and oscillating magnet arrays.resultsfluorescence intensity ( firefly luciferase ... |
about four decades ago , when hla - typed population samples from different geographic locations started to be available for comparative analyses , both allele frequencies and linkage disequilibrium measures revealed extensive geographic variation ( e.g. , [ 14 ] for europe ) .
these patterns were interpreted as expl... | next generation sequencing ( ngs ) is currently being adapted by different biotechnological platforms to the standard typing method for hla polymorphism , the huge diversity of which makes this initiative particularly challenging . boosting the molecular characterization of the hla genes through efficient , rapid , and... |
a 57-year - old woman came to iizuka hospital on march 12 , 2005 , with malaise and anorexia .
although she was a healthy hepatitis b virus carrier and negative for serologic markers of hepatitis a and c , testing upon admission showed elevated levels of liver enzymes ( alanine aminotranferase 752 iu / l , aspartate ... | we investigated a case of hepatitis e acquired after persons ate wild boar meat .
genotype 3 hepatitis e virus ( hev ) rna was detected in both patient serum and wild boar meat .
these findings provided direct evidence of zoonotic foodborne transmission of hev from a wild boar to a human . |
cell - cell communication in bacteria is accomplished through the exchange of chemical signaling molecules called autoinducers ( also called cell - density regulates factors ) .
this process , termed quorum sensing ( qs ; especially the n - acyl homoserine lactone , ahl ) , allows bacterial populations to coordinate ... | providencia sneebia strain st1 is a symbiotic bacterium ( belonging to phylum gammaproteobacteria ) with marine microalgae .
this bacterium exhibits the ability to produce n - acyl homoserine lactone signal molecule . to date , no genome that originates from marine providencia spp . has been reported . in this study ... |
oral health has a great impact on our overall health including both physical and psychological .
the who defines quality of life as individual 's perception of their position in life in the context of culture value system , in which they live and in relation to their goal , standards , and concerns .
a comprehensi... | background : to assess the prevalence of dental diseases among 915-year - old visually impaired children and find out its impact on their daily activities using the child - oral impact on daily performance ( c - oidp ) questionnaire in districts of uttarakhand , india.materials and methods : a total of 423 visually imp... |
to assess this question , we defined active hbv infection as the presence in serum of hepatitis b surface antigen ( hbsag ) and defined hcv seropositivity as the presence of hcv antibodies .
then we described the prevalence of hcv seropositivity and active hbv infection in hiv - positive patients from the cohort of t... | to determine if hepatitis c virus seropositivity and active hepatitis b virus infection in hiv - positive patients vary with patients geographic origins , we studied co - infections in hiv - seropositive adults .
active hepatitis b infection was more prevalent in persons from africa , and hepatitis c seropositivity w... |
necrosis and tissue degradation are the basic microscopic signs of acute necrotizing pancreatitis ( anp ) .
we believe that the microcirculation disorder is one of the strongest factors in the pathogenesis and morphogenesis of anp besides free radicals and of enzymatic origin .
this study is dedicated to investigat... | acinar necrosis is the basic microscopic sign of acute necrotizing pancreatitis ( anp ) .
microcirculation disorder is one of the major factors in the pathogenesis and morphogenesis of anp besides free radicals and damage of enzymatic origin .
this study is dedicated to the description of microscopic changes in the... |
advances in intensive care units as well as synchrony in multidisciplinary approaches allowed for expansion of possibilities in this field , such as conservative treatment .
indications for surgical management in blunt solid abdominal organ injuries have diminished in recent years . by definition renal trauma grade
... | renal trauma occurs in 15% of all trauma cases .
the kidney is the most commonly injured genitourinary and abdominal organ.in this case we present a 17year old patient with a grade iv trauma of the left kidney with renal rupture , hematoma , and urinoma .
he was referred to our hospital in hemodynamic stability ; ... |
given that it has more complications than diaper application in incontinence , it should be avoided in patients to the extent possible . however , for reasons relating to convenience in patient management , ignorance of the risks associated with catheterization , and medical inevitability , it is commonly performed . e... | purposeit is well known that fungi become predominant microorganisms in the urine of patients with long - term foley catheters .
this study was conducted to evaluate the lengths of time for fungi to cause urinary tract infection ( uti ) and to identify predictors of fungal uti in burn patients with long - term foley ... |
the ring - tailed lemur ( lemur catta l. ) has a very thin epidermis apart
from a few glabrous portions ( 1 ) .
the nose skin was
not included in the investigation but it belongs to the areas with a thick epidermis .
we
observed an unusual pattern of vascular smooth muscle cells in the lemur nose .
the morp... | the skin of the lemur nose tip ( rhinarium ) has arterioles in the outer vascular plexus
that are endowed with an unusual coat of smooth muscle cells .
comparison with the
arterioles of the same area in a number of unrelated mammalians shows that the lemur
pattern is unique .
the vascular smooth muscle cells ... |
sensory integration therapy is frequently performed by occupational therapists and pediatric practitioners as a service in schools . in the united states , the proportion of children who typically develop sensory integration dysfunction is 5%10%.1,2 a study in taiwan revealed that around 21%28% of preschool children ha... | backgroundthe purpose of this study was to investigate the effectiveness of sensory processing strategies in improving the activity level of children with sensory integration dysfunction.methodsthe
study used a matching - only pretest posttest control group design , which requires random matching of sensory integrat... |
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