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protection afforded by trialkyl phosphorothionates against the lung injury caused by trialkyl phosphorothiolates probably results from the inhibition by the p = s moiety of the thionates , of one or more pulmonary cytochrome p-450 isozymes .
the aromatic hydrocarbons p - xylene and pseudocumene also protect against t... | |
the majority of the serious alloimmune hemolysis cases are still due to rhd incompatibility , although abo maternal - fetal incompatibility is a much more commonly seen disorder . a much smaller fraction of the patients with hemolytic disease of the newborn ( hdn )
are due to sensitization to kell , duffy , kidd and ... | the kidd blood group is clinically significant since the jk antibodies can cause acute and delayed transfusion reactions as well as hemolytic disease of newborn ( hdn ) . in general , hdn due to anti - jkb incompatibility is rare and it usually displays mild clinical symptoms with a favorable prognosis . yet , we appar... |
we used a longitudinal health insurance database for people with catastrophic illnesses including md and cancer provided by the taiwan health research institute .
patients newly diagnosed with md and free of cancer would be eligible in our cohort ( icd-9-cm codes : 359.0 - 359.2 ) .
we skipped the first two years... | muscular dystrophies ( md ) comprise a heterogeneous group of hereditary myopathic diseases . in this group ,
myotonic md is associated with an increased cancer risk . however
, the cancer risk in other types of md is unclear . to address this gap in knowledge , we assessed data obtained from the taiwan health insu... |
study duration and animals : a total of 774 dairy cows from five dairy
farms within the prefecture of osaka , japan , were studied between 2010 and 2014 .
the age of
these animals was determined by the birth date associated with the individual identification
number assigned to each cow .
wbc and lymphocyte co... | analysis of the association between antibodies against bovine leukemia virus ( blv ) , blv
proviral load , and white blood cell ( wbc ) and lymphocyte counts was performed with 774
dairy cows .
the average age , wbc counts and lymphoid cell counts tended to be higher in
blv antibody - positive cows than in anti... |
the presence of alveolar bone with sufficient volume and/or density is considered a prerequisite for implant placement , integration and load bearing , and subsequent good outcomes.1 however , bone resorption following tooth extraction or due to pneumatization of the maxillary sinus may cause inadequate bone in the hor... | due to the angulation of maxillary bone as the maxillary bone resorption occurs from a buccal to palatal direction , bucco - lingually tilted implant placement is more likely especially in the posterior maxilla . the aim of this paper was to present a case restored by using a maxillary hybrid denture using cresco metho... |
the directives of the medical council sets out the principles and values on which good practice is founded ; these principles together describe medical professionalism in action
. principles of good medical practice exhorts practitioners to keep up - to - date in knowledge and skills , familiarize themselves with dev... | revalidation and renewal of registration are issues of concern to most psychiatrists .
keeping up - to - date with current knowledge is an essential part of the renewal of license to practice .
training needs of psychiatrists are addressed in postgraduate courses and the gaps in training and updating of knowledge a... |
their class iv lsy phenotype is recessive . due to its failure to complement what turned out to be a very unusual allele , called ot101 , of the zinc ( zn)-finger transcription factor che-1 , a terminal selector of asel and aser neuron fate ( etchberger et al .
2009 ) , we had assumed that ot146 was located on chromo... | functional diversification across the left / right axis is a common feature of many nervous systems .
the genetic programs that control left / right asymmetric neuron function and gene expression in the nervous system are , however , poorly understood .
we describe here the molecular characterization of two phenoty... |
tooth - colored restorative materials such as glass ionomer cements ( gics ) and composite resins ( crs ) have gained popularity due to increasing demand of esthetics . under acidic conditions ,
atomic force microscope ( afm ) is considered an important and applicable method for ra assessment .
rough surface of res... | objectives : to investigate the effect of acidic solution on surface roughness and microleakage of tooth - colored restorative materials.materials and methods : a 160 box - shaped cavities were prepared on the buccal surfaces of 160 human molars , and assigned to four groups : group a restored with ketac molar easymix ... |
paraesophageal hernias are uncommon in infants and children , and most of the reported cases are acquired resulting as a complication following nissen 's fundoplication for gastroesophageal reflux . acquired paraesophageal hernia is commonly seen in infants under the age of one year , neurologically impaired children ,... | congenital paraesophageal hernia is rare in infants and children .
this paper describes our experience with seven infants and children with congenital paraesophageal hernia with emphasis on two sisters who presented with unusually large paraesophageal hernias and herniation of most of the stomach resulting in intrath... |
there were 9 million new tb cases and approximately 2 million deaths from tb in 2004 .
more than 80% of all tb patients live in sub - saharan africa and asia . with the advent of hiv , tuberculosis is posing a serious health hazard , even in regions of the world where tuberculosis is not endemic .
the sternal and... | the case of a 20-year - old female who presented with refractory coccydynia and sternal pain is described .
she was immunocompetent , and had no systemic features .
she was diagnosed with tuberculosis of the sternal and coccygeal regions based on magnetic resonance imaging and histopathology of biopsy specimens .
... |
apart from its original definition as a regulator of calcium homeostasis , vitamin d ( vd ) is now known to have a broad spectrum of actions as illustrated by a large number of diseases resulting from an insufficient vd supply or vd metabolism ( fig . 1 ) .
interest in the role of epigenetics in vd metabolism is nou... | the bioactive vitamin d ( vd ) metabolite , 1,25-dihydroxyvitamin d3 regulates essential pathways of cellular metabolism and differentiation via its nuclear receptor ( vdr ) .
molecular mechanisms which are known to play key roles in aging and cancer are mediated by complex processes involving epigenetic mechanisms c... |
peripheral artery disease ( pad ) was firstly described in 1846 by brodie and is one of the most common manifestations of atherosclerosis . approximately 27 million individuals in the industrialized countries
the presence of pad is an independent predictor of cardiac and cerebral ischemic events [ 36 ] , and indivi... | peripheral artery disease ( pad ) is a common manifestation of atherosclerosis .
inflammation is important for initiation and progression of the disease .
dendritic cells ( dcs ) as antigen - presenting cells play an important role in the immune system .
therefore , we hypothesize that , in patients with pad , dc... |
propylthiouracil ( ptu ) , a thiourea derivative , is widely used for the treatment of graves disease .
the adverse effects of ptu include rash , arthralgia , fever , and transient leukocytopenia . although elevated transaminases are usually transient by discontinuing medication , severe liver dysfunction is reported... | abstracta 58-year - old woman was referred to our hospital because of liver dysfunction .
her serum levels of ast ( 619 iu / l ) and alt ( 603
iu / l ) had increased .
histological findings in the liver biopsy were compatible to autoimmune hepatitis ( aih ) , and the diagnosis of aih was confirmed by the diagnost... |
estimates of heritabilities and genetic correlations are essential population parameters required in animal breeding research and in design and application of practical animal breeding programmes .
genetic parameters are a characteristic of the population in which they were estimated and may change overtime due to se... | genetic and phenotypic parameters for production traits and somatic cell count ( scc ) for jersey dairy cattle in zimbabwe were estimated .
a total of 10986 lactation records were obtained from zimbabwe livestock identification trust , with cows calving in the period from 1996 to 2008 . an asreml program fitting an a... |
despite improvements in diagnosis and therapy over the last few decades , mortality of patients with acute coronary syndrome ( acs ) is still high . in the recent 10 years ,
a large percentage of patients post acs continue to experience cardiac events with high long - term mortality rates and overall suboptimal medic... | objectiveto investigate the relationship between staging of retinal artery lesions and the prognosis of acute coronary syndrome ( acs ) in a chinese population.methodsa total of 436 chinese patients with acs underwent coronary angiography and the eyes fundus examinations .
all the patients were divided into three gro... |
all the experiments were performed after getting the approval from ethical committee of institute ( dean/13 - 14/caec/189 dated 09 - 05 - 2013 ) .
experiments were performed on healthy male albino rats ( charles - foster strain ) , weighing between 200 and 300 g. the animals were kept in the 12:12 h light / dark cycl... | objective : intra - arterial injection of mesobuthus tamulus ( bt ) venom produces reflex vasosensory responses modulating cardiorespiratory parameters in albino rats . the present study was conducted to understand the role of kinin receptors in modulating vasosensory reflexes evoked by bt venom.materials and methods :... |
multiple sclerosis ( ms ) is a chronic autoimmune disease that causes deterioration of the myelin sheath leading to a myriad of neurological symptoms .
there is still no understanding of what causes ms or a cure for the disease .
fingolimod is an immunomodulatory drug that has recently been approved for the treatme... | background : while many studies have previously focused on fingolimod 's effect on immune cells , the effect it has on circulating and local central nervous system platelets ( plts ) has not yet been investigated .
this study will elucidate what effects fingolimod treatment has on multiple sclerosis ( ms ) patients p... |
lipoprotein(a ) [ lp(a ) ] consists of a low - density lipoprotein molecule that is covalently connected to the high - molecular - weight glycoprotein apolipoprotein(a ) [ apo(a ) ] .
plasma concentrations of lp(a ) are determined to a large extent by the size of the apo(a ) isoforms , which are expressed by a copy n... | aimsthe relevance of lipoprotein(a ) [ lp(a ) ] concentrations and low - molecular - weight ( lmw ) apo(a ) phenotypes in peripheral arterial disease ( pad ) has only been investigated by few studies .
therefore , we analysed this association in three independent cohorts and performed a mendelian randomization approa... |
diabetic nephropathy ( dn ) is a progressive kidney disease caused by angiopathy of capillaries in glomeruli secondary to longstanding diabetes .
it is the major cause of morbidity and mortality in patients with type-2 diabetes mellitus ( t2 dm ) .
diabetic foot infections ( dfi ) dfi are a serious complication of ... | backgroundcd200 ( ox-2 ) is a novel immune - effective molecule , existing in a cell membrane - bound form , as well as in a soluble form in serum ( s ox-2 ) , which acts to regulate inflammatory and acquired immune responses.material/methodswe planned this study to evaluate the sox-2 levels of type 2 diabetic foot ( g... |
redundant nerve roots ( rnrs ) of the cauda equine were first reported by verbiest20 ) in 1954 and named by cressman and pawl1 ) in 1968 .
although many reports of rnrs have been published since then , the mechanism of rnrs is still unclear .
it is described by a tortuosity of elongated and enlarged nerve roots in ... | objectivethere were previous reports of redundant nerve roots ( rnrs ) focused on their clinical significance and pathogenesis . in this study , we investigated the significant radiologic findings that correlate with rnrs occurrence
. these relations would provide an advanced clue for clinical significance and pathog... |
a 32-year - old male with profound intellectual disability and autism spectrum disorder presented to us from a psychiatric unit following seizures in the context of a new fever .
however , in the last 4 months , he required institutionalized psychiatric care due to new behavioral changes , including aggression , shou... | we present a case of 32-year - old male with profound mental retardation and autism spectrum disorder who had presented with seizures , rigidity and elevated creatine kinase and was initially diagnosed as neuroleptic malignant syndrome ( nms ) .
the patient subsequently had a complicated clinical course , developing ... |
convulsive syncope and epileptic seizures can both cause transient loss of consciousness ( loc ) , but these two conditions are often difficult to distinguish .
epileptic seizure is the result of an abnormal , excessive and hypersynchronous neuronal in the brain [ 1 - 5 ] .
the distinct pathophysiology underlying s... | it is important but difficult to distinguish convulsive syncope from epileptic seizure in many patients .
we report a case of a man who presented to emergency department after several witnessed seizure - like episodes .
he had a previous medical history of systolic heart failure and automated implantable converter ... |
human posture is determined and maintained by muscle coordination , proprioception ,
equilibrioception , and the position and function of the joints1 .
the ankle strategy that is applied to the ankle joints is an
important2 component of maintaining
postural adjustment and includes the proper use of hip joint mu... | [ purpose ] this study analyzed the effects of isotonic , isokinetic , and isometric
exercises of ankle joint muscles on lower extremity muscle activity and balance control .
[ subjects and methods ] the subjects were 30 healthy adults ( 15 males ) in their 20s who
were randomly assigned to three different exerci... |
the widespread use of genetic and non - genetic biomarkers as surrogate endpoints is a goal that scientists have long been pursuing , aiming to describe risks , exposures , intermediate effects of treatments , and biologic mechanisms .
biomarkers are measurements that indicate biological processes , and can be used i... | in this paper we discuss the consensus view on the use of qualifying biomarkers in drug safety , raised within the frame of the xxiv meeting of the spanish society of clinical pharmacology held in mlaga ( spain ) in october , 2011 .
the widespread use of biomarkers as surrogate endpoints is a goal that scientists hav... |
secondary cardiac tumors are 20 to 40 times more frequent than primary cardiac malignancies.1 ) the most common secondary tumors of the heart originate from leukemia , melanoma , lung cancer , breast cancer , and lymphoma.2 ) cardiac involvement may arise from hematogenous metastases , direct invasion from the mediasti... | most cases of cardiac metastasis from renal cell carcinoma ( rcc ) involve the vena cava or right atrium . left ventricular metastases from rcc without involving the vena cava or right atrium are extremely rare .
herein we report a case of rcc with left ventricular metastasis causing left ventricular outflow obstruct... |
secondary sclerosing cholangitis ( ssc ) is a rare form of sclerosing cholangitis with similar clinical features to that of primary sclerosing cholangitis ( psc ) . unlike psc
the diagnosis of ssc is conducted via three analytical pathways : serologic testing , radiological imaging and histological analysis .
while... | sclerosing cholangitis is a chronic cholestatic liver disease defined by both inflammatory and fibrotic changes of the biliary tract leading to diffuse stricture formation .
this entity exists in both a primary and secondary form . here
we present a rare case of secondary sclerosing cholangitis due to direct metast... |
temporary drainage of the upper urinary tract is a routine procedure to ensure renal function and to treat pain caused by ureteral obstruction .
internal ureteral stents offer a simple and effective method of ureteral drainage and avoid external devices .
irritative voiding symptoms were reported in 78% of patients... | purposetemporary drainage of the upper urinary tract by use of internal ureteral stents is a common procedure that is often associated with a variety of symptoms .
the role of intravesical stent position in associated morbidity is controversial.materials and methodsthe german version of the ureteral stent symptom que... |
the o - vinyl benzylzinc reagent 8 , the a - ring precursor , was derived from the benzyl bromide 14 , which was prepared in amounts up to 47-g by the four - step sequence shown in figure 3 ( via intermediates 1013 ) .
direct insertion of zinc25 into the carbon - bromine bond of the benzyl bromide 14 was attempted on... | the cortistatins are a recently identified class of marine natural products characterized by an unusual steroidal skeleton and have been found to inhibit differentially the proliferation of various mammalian cells in culture by an unknown mechanism .
we describe a comprehensive route for the synthesis of cortistatins... |
major histocompatibility complex ( mhc ) restriction of t lymphocytes was first reported by doherty and zinkernagel ( 1975 ) .
they provided experimental proof that t cells can only respond to peptide antigens when they are presented in complex with host - derived mhc molecules , existing in a class i and class ii va... | cross - presentation of endocytosed antigen as peptide / class i major histocompatibility complex complexes plays a central role in the elicitation of cd8 + t cell clones that mediate anti - viral and anti - tumor immune responses . while it has been clear that there are specific subsets of professional antigen present... |
cachexia leads to nutritional deficits including anorexia and loss of fat and muscle mass . in persons with precachexia or early cachexia , for example , old persons with weight loss and chronic obstructive pulmonary disease ,
there is strong evidence that nutritional support improves outcomes .
limited evidence su... | |
postoperative pain is very difficult to treat because it comprises different types of pain , including pain with a neuropathic component
. the mechanisms of neuropathic pain are still not well understood , so treatment for this type of pain remains difficult .
chemical modulators of pain are released in the spinal ... | backgroundapproximately half of all patients who undergo surgery develop postoperative pain , the mechanisms of which are not well understood by anesthesiologists .
d2-like receptors in the descending dopaminergic pathway play an important role in regulation of pain transmission in the spinal cord .
impairment of i... |
in most developed nations , the rate of paediatric cochlear implantation ( ci ) has increased to the point where it is now the predominant response to profound and , increasingly , severe childhood deafness .
the majority of published studies investigating ci in children have focused on children 's audition , speech ... | this paper provides an overview and a synthesis of the findings of a large , multifaceted study investigating outcomes from paediatric cochlear implantation . the study included children implanted at several australian implant clinics and attending a variety of early intervention and educational settings across a range... |
accurate and reproducible prostate ultrasound volume acquisition , precise implantation of the needle and placing seeds guided by an optimized plan are essential requirements to perform high quality prostate implants .
pre - planning ultrasound studies have value in that anatomic variation such as pubic arch interfer... | purposeto perform a dosimetric comparison between a pre - planned technique and a pre - plan based intraoperative technique in prostate cancer patients treated with i-125 permanent seed implantation.material and methodsthirty patients were treated with i-125 permanent seed implantation using trus guidance .
the first... |
in
the preceding paper in this issue , the mechanism of palladium - catalyzed
cross - coupling of alkenylsilanolates with aryl halides
was investigated . from a combination of
kinetic analysis of catalytic reactions ,
x - ray structure determination
of stable complexes bearing phosphine ligands , and stoich... | through
the combination of reaction kinetics ( both stoichiometric
and catalytic ) , solution- and solid - state characterization of arylpalladium(ii )
arylsilanolates , and computational analysis , the intermediacy
of covalent adducts containing si o pd linkages in the
cross - coupling reactions of arylsil... |
although the infection is acquired through inhalation of airborne propagules , most pulmonary infections are clinically silent and the disease usually manifests when it disseminate to extrapulmonary sites , most notably to central nervous system ( cns ) .
we report here a case of disseminated cryptococcosis presentin... | cryptococcosis is a systemic fungal infection associated with significant morbidity and mortality .
it predominantly affects people with immunosuppresion and human immunodeficiency virus infection .
extrapulmonary dissemination is rare in immunocompetent hosts .
we present here a case of disseminated cryptococcos... |
for a small cylindrical pore in an insulating membrane separating two electrolyte solutions , application of potential across the membrane produces an electric field profile away from the pore mouth ( r > 0 ) , which varies as
v(r)=d28lrv , where r is the distance from the pore mouth , d is the pore diameter , l its ... | solid - state nanopores are sensors capable of analyzing individual unlabelled dna molecules in solution .
while the critical information obtained from nanopores ( e.g. , dna sequence ) is the signal collected during dna translocation , the throughput of the method is determined by the rate at which molecules arrive ... |
ticks are considered to be second worldwide to mosquitoes as vectors of human diseases , while in livestock industry , ticks and tick - borne diseases ( tandtbds ) and emanating secondary infections adversely impede its development particularly in sub - saharan africa , latin america and asia .
however , the extend o... | a 30-year - old african woman in kenya succumbed to severe swollen regional lymph nodes , development of painful boils and ulcer formation and rashes at specific tick - biting sites together with an intermittent fever and headache following repeated tick bites of rhipicephalus pulchellus .
she later developed nuchal ... |
the differential diagnosis of generalized pustular eruptions with acute onset includes pustulosis acuta generalisata ( pag ) , acute generalized exanthematous pustulosis ( agep ) , and generalized pustular psoriasis ( gpp ) .
pag is characterized by scattered pustules with a red halo on normal skin with initial invol... | generalized pustular lesions characterized by acute onset with fever occur in pustulosis acuta generalisata , acute generalized exanthematous pustulosis , and generalized pustular psoriasis . in the present report
, we describe a pediatric case of generalized pustular eruption that was not completely consistent with ... |
increasingly , oncologists and pathologists are using next - generation sequencing assays to identify potential therapeutic targets that may help successfully treat malignancy . multiple oncology trials to assess the utility of next - generation sequencing ( ngs ) assays are underway .
although ngs assays are intende... | next - generation sequencing ( ngs ) technology is increasingly utilized to identify therapeutic targets for patients with malignancy .
this technology also has the capability to reveal the presence of constitutional genetic alterations , which may have significant implications for patients and their family members .... |
, the national institutes of health ( nih ) has recognized the field of nanomedicine in its roadmap for medical research.1 in 2007 , the strategic plan of the us national nanotechnology initiative identified training of a workforce skilled in the application of nanotechnology for public benefit as a primary goal.2 in 2... | the nanomedicine program at northeastern university provides a unique interdisciplinary graduate education that combines experiential research , didactic learning , networking , and outreach .
students are taught how to apply nanoscience and nanotechnology to problems in medicine , translate basic research to the dev... |
standards of f2-ip ( 5[r]-ipf2-vi , 5[s]-ipf2-vi , 5-ipf2-vi - d11 , 8-iso-15[s]-pgf2 , 8-iso-15[r]-pgf2 , 8-iso-15[s]-pgf2-d4 , and 15[r]-pgf2 ) , 15(s)-pgf2 ( hereafter referred to as pgf2 ) , 20:4 , and 20:4-d8 were from cayman chemicals ( ann arbor , mi ) .
methanol ( fisher scientific inc . ) , hexane , and ethy... | objective : we aimed to investigate the role of oxidative stress in the progression of multiple sclerosis ( ms).methods : we determined by liquid chromatography tandem mass spectrometry nonenzymatic ( f2-isoprostanes ) and enzymatic oxidation products of arachidonic acid ( prostaglandin f2 [ pgf2 ] ) in plasma and csf... |
compounds containing the glitazone / thiazolidinedione moiety have been synthesized and screened for binding to diverse molecular targets . as can be seen from the following list ,
some of this targets are protein kinases and phosphatases . in terms of in vitro analytical pharmacology , this implies that kinetics of ... | glitazones ( thiazolidinediones ) are drugs used for diabetes mellitus type 2 . by binding to peroxisome proliferator - activated receptor ( ppar ) they modulate transcription of genes of carbohydrate and lipid metabolism . through ppar stimulation , however , glitazones also affect other genes , encompassing inflamma... |
the derivation cohort is the lothian birth cohort 1936 ( lbc1936 ) , community - dwelling older subjects born in 1936 , now being studied to determine lifetime influences on aging .
the replication cohort is a prospective study of patients with recent nondisabling ischemic stroke , the mild stroke study ( mss ) .
t... | objective : to determine the magnitude of potentially causal relationships among vascular risk factors ( vrfs ) , large - artery atheromatous disease ( lad ) , and cerebral white matter hyperintensities ( wmh ) in 2 prospective cohorts.methods:we assessed vrfs ( history and measured variables ) , lad ( in carotid , cor... |
diabetic retinopathy ( drp ) is one of the main reasons of blindness [ 1 , 2 ] . microvascular and macrovascular damage developing in consequence of chronic hyperglycemia has a negative effect on the retina .
one of the pathologic changes in drp is retinal ischemia and oxidative stress - related neovascularization [ ... | purpose . to investigate the oxidant and antioxidant status of patients with type 2 diabetes mellitus and nonproliferative diabetic retinopathy ( drp )
. methods .
forty - four patients who had cataract surgery were enrolled in the study .
we included 22 patients with drp in one group and 22 patients in the contr... |
transradial approach ( tra ) for intravascular intervention is featured by less frequent hemorrhage at access site , improved patients comfort and shorter hospital stay . radial artery ( ra )
occlusion ( rao ) in patients undergoing coronary intervention via tra ( trci ) , is reported to be around 5%-10% , a complica... | background : radial artery ( ra ) occlusion ( rao ) is not rare in patients undergoing coronary intervention by transradial approach ( trci ) . predictors of and prevention from rao have not been systematically studied .
this study aimed to analyze the risk factors of the weakness of ra pulsation ( rap ) and its pred... |
the neuropeptide which is most well known in the group is substance p ( sp ) .
sp has pronounced pro - inflammatory effects , including the promotion of extravasation and accumulation of leukocytes at sites of injury .
sp is also involved in the so - called neurogenic inflammation , wound healing , and angiogenesis... | muscle injury and inflammation ( myositis ) in a rabbit model of an unilateral muscle overuse were examined .
it is unknown if the tachykinin system has a functional role in this situation . in this study , therefore , the neurokinin-1 receptor ( nk-1r ) expression patterns were evaluated .
white blood cells , nerv... |
samples from 8 provinces ( 24 farms ) in thailand from december 2007 through march 2008 were submitted to the veterinary diagnostic laboratories of kasetsart university and chulalongkorn university .
a total of 33 porcine samples were confirmed as positive for pedv by reverse transcription
pcr ( rt - pcr ) ( 4 ) be... | since late 2007 , several outbreaks of porcine epidemic diarrhea virus ( pedv ) infection have emerged in thailand .
phylogenetic analysis places all thai pedv isolates during the outbreaks in the same clade as the chinese strain js-2004 - 2 .
this new genotype pedv is prevailing and currently causing sporadic outb... |
obstructive sleep apnea ( osa ) affects approximately 10% of the adult population , and is characterized by repetitive upper - airway collapses during sleep with concomitant loss of airflow.1 the autonomic , physiologic , and neurophysiological consequences of osa are severe , and mandate understanding of mechanisms un... | introductionobstructive sleep apnea ( osa ) is a male - predominant condition , characterized by repeated upper - airway collapse with continued diaphragmatic efforts during sleep , and is accompanied by severe physiological consequences .
multiple morphological aspects , including epiglottis cross - sectional area (... |
free oxygen radicals are neutralized by the antioxidant system and a balance is maintained . when this balance is impaired , however
it is known that increasing free oxygen radicals in newborns damages the cell membrane by way of lipid peroxidation , and this damage may be associated with various pathologies recorded... | objectivein this study , we aim to demonstrate that measurement of the malondialdehyde ( mda ) level in the umbilical cord blood of newborn infants born via cesarean section ( c / s ) and normal vaginal delivery ( nvd ) is indicative of oxidative stress during the perinatal period.methodsthe study was conducted at baki... |
the il-6 -174g > c functional gene variant has previously been studied in relation to the risk of coronary heart disease ( chd ) , juvenile onset chronic arthritis and primary sjogren 's syndrome .
the promoter region of this gene contains many functional sites including a multiple response element ( -173 to -145 )... | backgroundmicroalbuminuria and subsequent progression to proteinuria and nephropathy is associated with increased oxidative stress , increased inflammatory cytokines and increased cardiovascular ( cvd ) risk .
the common functional il-6 -174g > c gene variant is also associated with elevated levels of inflammatory cy... |
brown norway ( bn ) and bb rats were propagated as described ( 5,6 ) . before euthanization
, animals were fasted for 16 h , and those possessing blood glucose levels > 130 mg / dl were disqualified from studies of pre - diabetes .
human recombinant il-1ra ( hil-1ra ) ( 350 g / kg / day ) or vehicle ( saline ) was ... | objectiveinflammatory mediators associated with type 1 diabetes are dilute and difficult to measure in the periphery , necessitating development of more sensitive and informative biomarkers for studying diabetogenic mechanisms , assessing preonset risk , and monitoring therapeutic interventions.research design and meth... |
the expected life span of patients diagnosed with malignant spinal metastasis varies from several months to years depending on the aggressiveness of the primary tumor and the visceral involvement4 ) . for these reasons ,
the surgical goal for spinal metastasis is pain relief and restoration of physical function durin... | objectivewe evaluated the validity of bone cement - augmented percutaneous screw fixation for treating malignant spinal metastases.methodsbetween 2011 and 2015 , 14 patients ( eight men and six women ) who underwent bone cement - augmented percutaneous screw fixation for malignant spinal metastases were enrolled in thi... |
infectious spondylodiscitis is common inflammatory disorder and serious condition that can occur spontaneously or postoperatively at vertebral body , intervertebral disc , spinal canal and paravertebral soft tissue4,16 ) .
infectious spondylodiscitis is characterized clinically by relatively non - specific symptoms s... | objectivethe objective of this study was to evaluate and compare the diagnostic value of the open biopsy technique and the percutaneous biopsy techniques in lumbar spondylodiscitis.methodsbetween january 2004 and december 2009 , we retrospectively reviewed the medical records of 57 patients with infectious lumbar spond... |
atypical deglutition111 is a pathological phenomenon affecting an increasing number of people in the general population.12 ad is characterized by the persistence in adults of swallowing typical in infants .
several studies have investigated the etiology1320 and treatment21 24 of the condition . despite few relevant r... | backgroundatypical deglutition is exacerbated by stress and anxiety .
several therapeutic approaches have been employed to treat stress and anxiety disorders , ranging from typical psychopharmacological strategies to novel physical protocols , such as transcranial magnetic stimulation and radioelectric asymmetric con... |
note the microbubbles appearing first in the right atrium , immediately after in the diverticulum and right ventricle . | a 12yearold spayed female miniature poodle presented for coughing , respiratory distress , and anorexia .
after thoracentesis for pleural effusion , radiography revealed an enlarged cardiac silhouette with a bulge in the area of the body of the right atrium .
echocardiography revealed an anechoic chamberlike cavity... |
hepatitis c virus ( hcv ) infection is one of the major epidemics afflicting young adults . in some countries
the effective management of the new cases is critically important because , without treatment , patients will develop chronic hcv infection , hcv - related cirrhosis , liver failure , and hepatocellular carci... | background : hepatitis c virus ( hcv ) infection is common worldwide .
the treatment typically involves a combination of interferon - alpha ( ifn- ) and ribavirin ( rbv ) therapy ; however , the use of ifn- is well documented to be associated with thyroid disease , the most common autoimmune disorder associated with ... |
many infectious agents and immunological mechanisms may play a role in pathogenesis of guillain - barre syndrome ( gbs ) .
it is possible to identify the four most common subtypes : the acute inflammatory demyelinating polyradiculoneuropathy ( aidp ) , the acute motor axonal neuropathy ( aman ) , the acute motor and ... | acute motor and sensory axonal neuropathy ( amsan ) are recently described subtypes of guillain - barre syndrome characterized by acute onset of distal weakness , loss of deep tendon reflexes , and sensory symptoms .
a 21-yr - old male was transferred to our hospital due to respiration difficulties and progressive we... |
bisphosphonates are the first line of treatment for metastatic bone cancer , osteoporosis , and paget 's disease . in the late 2003 ,
cases of bisphosphonate - related osteonecrosis of the jaw ( bronj ) were first reported . since then , many studies have been performed in order to provide early diagnosis and better ... | objectives . this paper offers a critical review of published information on the imaging strategies used for diagnosing bisphosphonate - associated osteonecrosis of the jaw ( bronj ) in patients taking intravenous bisphosphonates , pointing at the different methodologies and results of existing literature .
methods .... |
for the past 20 years , video - assisted thoracoscopic surgery ( vats ) has become the major method for invasive diagnosing or resecting pulmonary and mediastinal diseases , because vats offers lower postoperative pain , and better cosmetics and recovery for patients .
the pursuit for ultimate minimal invasiveness ke... | abstractour study sought to review our experience from biportal to uniportal video - assisted thoracoscopic surgery ( vats ) major lung resection .
lessons we learned from the evolution regarding technical aspects were also discussed.we retrospectively reviewed patients who underwent vats lobectomy or segmentectomies... |
thioglycosides are
widely used as glycosyl donors in the synthesis
of complex oligosaccharides because their stability , ease of activation ,
and flexibility in the tuning of glycosyl coupling conditions .
numerous
thioglycosyl donors have been developed , resulting in both technological
advances and mechan... | in
this article , we evaluate glycosyl dithiocarbamates ( dtcs ) with
unprotected c2 hydroxyls as donors in -linked oligosaccharide
synthesis . we report a mild , one - pot conversion of glycals into -glycosyl
dtcs via dmdo oxidation with subsequent ring opening by dtc salts ,
which can be generated in situ f... |
the term fibromatosis ( fm ) was originally proposed by stout for mesenchymal tumors characterized by the presence of proliferating fibroblasts , myofibroblasts , and marked collagen .
it includes a broad group of myofibroblastic lesions with intermediate biologic behavior between benign fibrous lesions and fibrosar... | extra - abdominal desmoid tumors are known as aggressive fibromatosis ( afm ) .
synchronous and metachronous multicentric aggressive fibromatosis are rare lesions and pose dilemma in diagnosis and management . a rare and interesting case of recurrent multicentric , synchronous afm is presented which to the best of ou... |
type 1 diabetes mellitus ( t1 dm ) is one of the most common pediatric endocrine illnesses . of these ,
over half are living in developing nations , with india being home to an estimated 97,700 children with t1 dm . data were collected from hospital - based studies in 1990 from india suggest that young diabetics ( on... | it is estimated that india is housing about 97,700 children with type 1 diabetes mellitus ( t1 dm ) .
a study of 30 children with insulin - dependent diabetes with age at diagnosis 15 years , conducted in 1992 , reported a prevalence of 0.26/1000 children .
the peak age at diagnosis was 12 years .
this was the fi... |
the development of the human dentition is regulated by tissue interactions and genetic networks similar to those of other ectodermal organs and involves iterative and self - organizing mechanisms crucial for the serial organization of teeth and their shape and renewal.13 various types of developmental aberrations are c... | objective : the aim of this study was to determine the prevalence of double teeth , hypodontia , microdontia , and hyperdontia of primary teeth in turkish children.methods:the study group comprised 1149 children ( 554 girls , 595 boys ) .
the children were examined in twelve local nurseries in sivas , turkiye .
cli... |
caveolae were described first in 1953 by palade as flask - or omega - shaped plasma membrane invaginations , with a diameter of 50100 nm .
these characteristic membrane invaginations are abundantly present in many but not all eukaryotic cell membrane .
biochemical studies revealed that caveolae are detergent resi... | endocytosis the uptake of extracellular ligands , soluble molecules , protein and lipids from the extracellular surface is a vital process , comprising multiple mechanisms , including phagocytosis , macropinocytosis , clathrin - dependent and clathrin - independent uptake such as caveolae - mediated and non - caveola... |
existence of microorganisms , their products , or necrotic pulp tissue can cause pathologic changes , several lesions , and bone resorption in the periradicular tissues . therefore , one of the most important goals of dentistry treatment is elimination of microorganisms . in a root canal therapy attempts
should be ma... | aim : the presence of calcium hydroxide ( ca(oh)2 ) in the root canal interferes with the apical root canal sealing and may result in periapical lesions in the long run . the present study was aimed to compare the efficacy of two rotary systems of race and mtwo in the removal of ca ( oh)2 aqueous - based from distobucc... |
though grouped in the mood disorders section of dsm , primary depressive disorder ( unipolar depression , up ) and bipolar disorder ( bp ) show clearly distinctive features , most strikingly because patients share the possibility of experiencing major depression but differ in the susceptibility for mania .
genetic ... | objectives . patients affected by bipolar disorder ( bp ) and major depressive disorder ( up ) share the susceptibility to experience depression and differ in their susceptibility to mania , but clinical studies suggest that the biological substrates of the two disorders could influence the apparently similar depressiv... |
the circle of willis , whose function is to protect the brain from ischemia , is the main structure that provides a constant and regular blood flow to the brain .
the circle of willis is an arterial polygon and is a vascular ring composed of branches of arteria ( a ) carotis interna and a. basilaris .
this circle i... | backgroundthe circle of willis is a major collateral pathway important in ischemic conditions .
the aim of our study was to assess the structural characteristics of the circle of willis within the turkish adult population , along with variations and arteries involved in the measurement of diameters and lengths on cra... |
glucokinase ( gk ) ( ec 2.7.1.1 ) is expressed in glucosensitive cells of the pancreas , liver , hypothalamus , anterior pituitary gland , and enteroendocrine k and l cells [ 13 ] .
gk has a prominent role as a glucose sensor because of its specific kinetic properties , including an affinity for glucose that is withi... | recent reports point out the importance of the complex gk - gkrp in controlling glucose and lipid homeostasis .
several gk mutations affect gkrp binding , resulting in permanent activation of the enzyme .
we hypothesize that hepatic overexpression of a mutated form of gk , gka456v , described in a patient with pers... |
schizophrenia is a continuous , life time major psychiatric disorder that may affect children , adolescents and adults .
depression is episodic , recurrent in nature , characterized by low mood , decreased psychomotor activity and depressive cognitions .
caring role is not an easy task and that may impact on their ... | background : family care burden among schizophrenia and depressive disorders has not been addressed in the research .
family burden was significantly high in patient with schizophrenia except the effect on physical health of other family member .
comparing burden in these two groups may help in the psychosocial man... |
physical activity is an important clinical parameter related to morbidity and mortality in many chronic diseases , including chronic obstructive pulmonary disease ( copd).1 physical activity is defined as any bodily movement produced by skeletal muscles that results in energy expenditure beyond resting energy expenditu... | backgroundthe purpose of this study was to quantify the walking time and frequency of postural changes in daily life in patients with chronic obstructive pulmonary disease ( copd ) using a new triaxial accelerometer system.methodstwenty-six elderly patients with stable copd ( age 76.8 6.2 years ; percent forced expira... |
porcelains are highly esthetic materials extensively used in dentistry to construct
various types of restorations and prostheses such as porcelain fused to metal crowns ,
veneers , inlays , onlays and all ceramic restorations .
they fulfill the esthetic and
functional demands of the patients by their superior p... | objectivethe aim of this study was to evaluate the flexural strength of two porcelain
materials ( ips d.sign and ips e.max ceram ) exposed to erosive agentsmaterial and methodsone hundred and twenty bar - shaped specimens were made from each of
fluorapatite - leucite porcelain ( ips d.sign ) and fluorapatite porcel... |
water
plays a fundamental role in a wide range of fields of study ,
including geology , atmospheric sciences , chemistry , biology , and physics . because of its relevance and ubiquity ,
water
is the most common solvent in experimental and computational studies
of biological systems . the hydrophobic
effect... | we have developed an automated parameter
optimization software
framework ( paropt ) that implements the nelder mead simplex
algorithm and applied it to a coarse - grained polarizable water model .
the model employs a tabulated , modified morse potential with decoupled
short- and long - range interactions inc... |
typhoid fever is a common infection that has continued to be a public health problem in many developing countries , particularly in areas with poor sanitation and limited availability of clean , potable water .
the world health organization ( who ) conservatively puts the annual global incidence of typhoid fever at 2... | surgical complications of typhoid fever usually involve the small gut , but infrequently typhoid fever also involves the gallbladder .
complications range from acalculous cholecystitis , gangrene to perforation . here , we present a case of enteric fever with concomitant complication of multiple ileal perforations at... |
the shortened dental arch ( sda ) concept aims at maintaining a functional dentition for middle - aged and elderly patients by concentrating treatment efforts at preservation and restoration of the strategically important parts of the dentition , that is , the anterior and premolar teeth , and avoiding extensive restor... | objective . this study aimed to investigate the impact of subject age , gender , and arch length on dentists ' attitudes towards
unrestored shortened dental arches .
materials and methods .
93 syrian dentists were interviewed and presented with 24 scenarios for male and female subjects of different ages and short... |
malaria in pregnancy is an important cause of anaemia , miscarriages , intrauterine growth restriction , low birth weight , still birth and other pregnancy - related complications.1 several studies have reported that 125 million women worldwide and 25 - 50 million african women who get pregnant annually are at risk of ... | background : malaria infestation during pregnancy is mostly asymptomatic and untreated especially in unbooked pregnancies .
it presents with almost all the fetal complications of overt malaria in pregnancy .
the aim of this study was to determine the effect of asymptomatic malaria parasitaemia on the neonates of un... |
left ventricular hypertrophy ( lvh ) and diastolic dysfunction are the early manifestations of cardiac damage in patients with arterial hypertension characterizing hypertensive heart disease.1 in response to a variety of mechanical , hemodynamic , hormonal and pathologic stimuli , the heart adapts to increased demands ... | background : spontaneously hypertensive rats develop left ventricular hypertrophy , increased blood pressure and blood pressure variability , which are important determinants of heart damage , like the activation of renin - angiotensin system.aims:to investigate the effects of the time - course of hypertension over 1 )... |
the most common causes of lymphoma - related neuropathy are local infiltration of lymphoma and proliferation of the lymphoma inside of peripheral nerve tissue ( 1 ) .
other causes of lymphoma - related neuropathy are loss of dorsal root ganglion cells , ( 2 ) the neurotoxic effects of drugs such as vincristine , ( 3 ... | peripheral neuropathies occur in lymphoma patients .
causes of neuropathy include chemotherapy , opportunistic infections , and the lymphoma itself .
we report a patient with lymphoma whose chief complaint was a sensory loss in the hands and feet .
electrophysiologic studies and sural nerve biopsy showed sensory ... |
among the various sources for the development of new drugs , compounds from living organisms , so called natural products , are of particular significance .
approximately one third of today s best selling drugs are either natural products or have been developed based on lead structures provided by nature .
recent e... | the supply problem with regard to drug development and sustainable production lies in the limited amounts of biomass of most marine invertebrates available from wild stocks .
thus , most pharmacologically active marine natural products can only be isolated in minute yields .
total synthesis of pharmacologically act... |
retinal degenerative diseases remain an important cause of blindness in current years . in those conditions
retinal cells suffer progressive damage , which can not be avoided or replaced by modern therapeutic approaches .
cell - based therapies including neural and stem cells represent an excellent perspective for ... | purpose .
the purpose of this work was to evaluate the retinal integration and differentiation of neurospheres formed by stem cells and mouse neural progenitor cells injected intravitreally in mice eyes with retinal injury .
methods .
eight male c57bl mice , 8 weeks old , were submitted to intraperitoneal injecti... |
in recent years the economy of energy markets has been interested by deep transformations due to political as well as technological changes all over the world .
such innovations have been often characterized by procedures of liberalisation which have often led to the creation of completely new markets as in the case ... | in the present paper we exploit the theory of ambit processes to develop a model which is able to effectively forecast prices of forward contracts written on the italian energy market .
both short - term and medium - term scenarios are considered and proper calibration procedures as well as related numerical results ... |
the multifactorial model of the cause of delirium , as a fluctuating disorder of attention and cognition , recognizes a complex interplay between predisposing and precipitating factors
. cognitive impairment of different degrees of severity , including clinically manifest dementia , is recognized as one of the most i... | background / aimsalthough delirium is generally regarded as a transient syndrome , persistence of delirium in patients with cognitive impairment even with fatal outcome has been reported as well .
this study aims to describe the clinical features and neuropathological correlates of this type of delirium.methodsincl... |
docking simulations and virtual screening are being routinely used in drug design , enabling rapid identification of hits and lead compounds [ 1 - 3 ] .
the goal of docking simulations is to determine the binding mode ( bound conformation ) and the strength of binding ( binding affinity ) between a ligand , which is ... | progress in functional genomics and structural studies on biological macromolecules are generating a growing number of potential targets for therapeutics , adding to the importance of computational approaches for small molecule docking and virtual screening of candidate compounds . in this review ,
recent improvement... |
a 56-year - old female presented to her primary care physician with sharp left upper quadrant pain of 2 weeks duration .
work - up including a ct scan of her chest , abdomen and pelvis revealed cervical , axillary , retroperitoneal , mesenteric , periceliac and porta hepatis lymphadenopathy , and marked splenomegaly ... | a patient with a previous history of epithelial ovarian cancer presented to her physician with diffuse adenopathy . on subsequent evaluation , she was found to have a follicular lymphoma .
work - up revealed an elevated serum ca-125 antigen level , raising the question of whether the laboratory abnormality represente... |
complete obturation of the root canal system with an inert filling material and creation of a hermetic , apical seal have been proposed as goals for endodontic treatment.1 since the most common cause of endodontic failure has been attributed to incomplete obturation , many different obturation techniques have been deve... | objectivesto investigate apical leakage of roots filled with 6 different gutta - percha techniques ; thermafil , js quick - fill , soft core , microseal , system b and lateral condensation using a new computerized filtration meter.materials and methods60 extracted single rooted teeth were used .
coronal part of each ... |
a 52-year - old man who had postprandial abdominal distension and right upper quadrant abdominal pain visited the gastroenterology department .
on the abdominal computed tomography ( ct ) angiogram , a 4.52.8 cm heterogeneous enhancing mass with intraluminal obstruction was observed in the infrahepatic and the suprar... | primary leiomyosarcoma of the inferior vena cava ( ivc ) is a rare malignant tumor .
herein , we report the case of a 52-year - old male patient who had postprandial abdominal distension and right upper quadrant abdominal pain . the abdominal computed tomography ( ct ) angiogram showed an ivc mass extending from the ... |
radiotherapy ( rt ) is an important part of head and neck cancer treatment , either as the primary modality or as an adjuvant treatment2 .
the radiation field for rt of nasopharyngeal and oropharyngeal cancers often includes 100% of the parotid gland13 .
rt causes acute or early and late toxicities , the severity o... | summary
introduction : radiotherapy ( rt ) of head and neck neoplasms often damages the salivary glands .
aim : to examine the pattern of morphologic changes resulting from rt of the head and neck region in minipig parotid glands in a clinical and experimental research setting .
methods : twelve 18-month - old... |
in the recent years spectroscopic schemes have made significant progress thanks to new developments in lasers and detection techniques .
today , laser - based sensing of chemical species offers high sensitivity and specificity , large dynamic range , multi - component capability , and lack of pretreatment or preconce... | this letter reports on mid - infrared laser - based detection and analysis of chemical species .
emphasis is put on broadly tunable laser sources and sensitive detection schemes . selected examples from our lab
illustrate the performance and potential of such systems in various areas including environmental and med... |
systemic sclerosis ( ssc ) is a connective tissue disorder characterized by vascular lesion and widespread fibrosis in organs such as skin , gut , lung , heart , and kidneys .
clinically , there is a broad spectrum of symptoms from widespread severe skin thickening ( diffuse ) to skin thickening limited to distal ext... | background : cardiac involvement in systemic sclerosis ( ssc ) is more prevalent than previously thought . in this study , the frequency and severity of cardiovascular involvement were assessed in ssc patients referred to firouzgar hospital.methods:fifty-eight patients with ssc , selected from the data bank of ssc pati... |
cardiovascular disease ( cvd ) , a leading cause of death in india , leads to premature death , disability , and financial catastrophe due to high out - of - pocket expenditures for acute cardiovascular care .
diabetes has been recognized as an independent risk factor associated with increased mortality during hosp... | objectives : to evaluate and compare clinical and epidemiological characteristics , treatment strategies , and utilization of evidence - based medicine ( ebm ) among coronary artery disease ( cad ) patients with or without diabetes.materials and methods : prospective observational cohort study from a tertiary care hosp... |
the goal of researchers working in the area of developmental toxicology is to prevent adverse reproductive outcomes ( early pregnancy loss , birth defects , reduced birth weight , and altered functional development ) in humans due to exposures to environmental contaminants , therapeutic drugs , and other factors . to b... | |
respiratory syncytial virus ( rsv ) is an enveloped , single - stranded , negative - sense rna virus with a genome of 15,200 bases and a member of the genus pneumovirus in the paramyxoviridae family . based on antigenic and genetic variability ,
rsv is classified into two groups , a and b ( 1 , 2 ) . respiratory sync... | backgroundhuman respiratory syncytial virus ( rsv ) is a leading cause of severe lower respiratory tract disease in the pediatric population , elderly and in immunosuppressed individuals .
respiratory syncytial virus is also responsible for bronchiolitis , pneumonia , and chronic obstructive pulmonary infections in a... |
atherosclerosis , long time viewed as a cholesterol storage disease , is today considered to be an inflammatory process involving cytokines and chemokines and the infiltration of monocytes and t - cells into the vessel wall .
fractalkine ( cx3cl1 ) is a chemokine expressed by multiple cells in the body with a cx3c mo... | introduction .
fractalkine is a chemokine associated with atherosclerosis .
increased serum levels have been reported in unstable coronary artery disease ( cad ) and to predict mortality in heart failure .
mediterranean - like diet and omega-3 fatty acids ( n3-pufa ) have documented cardioprotective and anti - in... |
the frequency of such malocclusions is 4080% in modern societies , 4379% in nordic countries and 89.9% in turkish population .
therefore , changes in facial musculature can give rise to skeletal irregularity . facial remodeling and growth
the majority of brain maturation happens in the first 2 years of life . durin... | objective : the aim of this study was to compare cephalometric variables of subjects with normal and cesarean births.materials and methods : ninety age- and gender - matched patients , who were treated in gaziantep university , faculty of dentistry orthodontics department were equally divided into normal and cesarean g... |
alpha-1 antitrypsin deficiency ( aatd ) is an autosomal codominant inherited condition characterized by low levels of alpha-1 antitrypsin in serum and tissues .
this protein , primarily produced in the liver , is the most prevalent protease inhibitor in serum and its main function is to inhibit neutrophil elastase , ... | introduction : intravenous augmentation therapy with purified intravenous alpha-1 antitrypsin replaces the deficient protein and is the only currently approved treatment for alpha-1 antitrypsin deficiency ( aatd ) related lung disease .
while augmentation therapy has been available for more than 20 years , there are ... |
arterial stiffness has emerged as an independent predictor of cardiovascular events and all - cause mortality .
thus , improving arterial stiffness may reduce the risk of cardiovascular events , all - cause mortality and end - organ damage .
methods of assessing arterial stiffness include the measurement of arteria... | backgroundseveral studies have tested the effects of allopurinol on arterial stiffness , but the results have been inconclusive .
we aimed to conduct a meta - analysis to investigate the impacts of allopurinol treatment on arterial stiffness , as measured by pulse wave velocity ( pwv ) and augmentation index ( aix).m... |
for the last couple of decades weight training has become increasingly popular due to its
well - documented numerous benefits , such as increasing muscular strength and raising resting
metabolism rates1 . according to nelson , in
a review article about the physical activity and public health of older adults ,
s... | the purpose of this study was to investigate the differences in muscle activation
patterns of the biceps brachii ( bb ) and flexor carpi radialis ( fcr ) muscles , while
measuring the resultant force ( rf ) at different shoulder flexion angles .
[ subjects ]
thirteen healthy males ( age 24.853.4 years , weight... |
to assess the prevalence of alcohol use among the students entering a public university in alagoas , brazil .
this was a cross - sectional study , analytically performed with young college graduates enrolled in all courses at a public university in alagoas , brazil , in 2006 .
a closed questionnaire , based on cage... | background : alcohol is the number one toxic substance consumed by people of all age groups , which makes its use a public health problem . the overall trend shows that university students are those who suffer the most pressure.objective:to assess the prevalence of alcohol use among students newly enrolled at a public ... |
a 19-month - old previously healthy boy presented with an 8-month history of watery rhinorrhea and nasal obstruction .
ct scans revealed a 2.7 3.5 cm well - defined , expansile mass in the left nasal cavity , extending to the anterior ethmoid sinus . the mass caused pressure remodeling of the adjacent bones without ... | we report ct and mr imaging findings for a case of nasal chondromesenchymal hamartoma occurring in a 19-month - old boy . a nasal chondromesenchymal hamartoma is a rare benign pediatric hamartoma that can simulate malignancy .
although rare , knowledge of this entity is essential to avoid potentially harmful therapie... |
mesenchymal tumors of the gastrointestinal tract are mainly spindle cell tumors , which include gastrointestinal stromal tumors ( gist ) , leiomyoma or leiomyosarcoma , and schwannomas . among these tumors ,
gastric schwannomas are usually benign but in some cases they are malignant [ 1 , 2 ] .
esophagogastroduoden... | a schwannoma is a kind of neurogenic tumor that rarely occurs in the gastrointestinal tract .
gastric schwannomas make up 0.2% of all gastric neoplasms .
gastrointestinal stromal tumors ( gist ) are the most common mesenchymal tumors and up to 6070% of gist occur in the stomach .
schwannoma and gist are similar i... |
there were 170 mrsa isolates from clinical and environmental samples collected in the period 20082009 that were subjected to antimicrobial susceptibility testing at the biotechnology research center in tripoli , libya .
the samples were collected at three hospitals , referred to herein as hospitals a ( n=95 ) , b ( n... | backgroundmethicillin - resistant staphylococcus aureus ( mrsa ) is a nosocomial ( hospital - acquired ) pathogen of exceptional concern .
it is responsible for life - threatening infections in both the hospital and the community.aimsto determine the frequency of mrsa misidentification in hospitals in tripoli , libya... |
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