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osteoarthritis ( oa ) is a degenerative disease starting with key molecular events that ultimately lead to the breakdown of the cartilage . the purpose of this study is to use two imaging methods that are sensitive to molecular and macromolecular changes in oa to better characterize the disease process in human osteo...
purposeosteoarthritis ( oa ) is a degenerative disease starting with key molecular events that ultimately lead to the breakdown of the cartilage . the purpose of this study is to use two imaging methods that are sensitive to molecular and macromolecular changes in oa to better characterize the disease process in huma...
recently , metabolic syndrome has become a serious health problem in advanced countries , and emphasis has been placed on reducing obesity , which is believed to be the main cause of metabolic syndrome . in particular , it was found that green tea and its components , catechins , caffeine , and theanine , have suppre...
to elucidate the inhibiting mechanisms of fat accumulation by catechins , caffeine , and epigallocatechin gallate ( egcg ) , icr mice were fed diets containing either 0.3% catechins or 0.1% egcg and/or 0.05% caffeine for 4 weeks . after the feeding , intraperitoneal adipose tissues weights were significantly lower in...
actinomycetes , gram - positive bacteria , represent an important source of biologically active compounds . in fact , they synthesize one - third of the antibiotics commercially available that is , the macrolide erythromycin , the glycopeptide vancomycin , and the cyclic lipopeptide daptomycin and other drugs like ...
actinomycetes are an important source of biologically active compounds , like antibiotics , antitumor agents , and immunosuppressors . genome sequencing is revealing that this class of microorganisms has larger genomes relative to other bacteria and uses a considerable fraction of its coding capacity ( 510% ) for the...
this study was approved by our institutional review board , and the behavioral variant ftd ( bvftd ) subjects as well as the normal controls ( nc ) were imaged after obtaining written informed consent from the subjects and/or their proxies . we studied brain stiffness in five male subjects with bvftd ( age range 5365...
purposeto investigate the feasibility of utilizing brain stiffness as a potential biomarker for behavioral variant frontotemporal dementia ( bvftd ) patients . magnetic resonance elastography ( mre ) is a noninvasive technique for evaluating the mechanical properties of brain tissue in vivo . mre has demonstrated d...
there have been only few reports in the literature describing this rare entity . in this study we report a case of gallbladder neurofibroma presenting as chronic epigastric pain in a young patient . a thirty two year old otherwise healthy man presented to our clinic with chronic epigastric pain symptom after eating...
context : benign nonepithelial neoplasms of the gallbladder are unusual . the majority of gallbladder neurofibromas are found incidentally in the gallbladder specimens following cholecystectomy . there have been only few reports in the literature describing this rare entity . in this study we report a case of gal...
chlorogenic acid is the ester of caffeic acid and quinic acid in shikimate pathway , which is commonly found in some plants , such as honeysuckle , cortex eucommiae , semen coffea arabica , and green tea . chlorogenic acid has antibacterial , antiviral , clear free radicals , and antitumor effects . in recent years ,...
objective . inhibiting gene -catenin and inducting genes gsk-3 and apc , promoting the tumor cell apoptosis in wnt pathway , by chlorogenic acid were discussed ( cga ) . method . the different genes were scanned by the 444k mouse microarray chips . the effect of the three genes was confirmed by rt - pcr technique w...
a 17-year - old girl presented with a six - month history of multiple asymptomatic brownish atrophic plaques in a zosteriform distribution on the left side of her trunk ( figure 1 ) . biopsy of a lesion showed a normal epidermis with increased pigmentation of the basal layer and a broad dermis with thickened collagen...
linear atrophoderma of moulin is a rare , acquired , linear dermatosis . we present a 17-year - old girl with multiple asymptomatic brownish atrophic plaques in a zosteriform distribution on the left side of the trunk . clinical presentation and dermatopathology was compatible with the diagnosis of linear atrophode...
the metabolic syndrome , also called " syndrome x " , " insulin resistance syndrome " , or " cardiometabolic syndrome " , refers to the state in which metabolic risk factors for cardiovascular diseases are clustered in individuals . the factors include abdominal obesity , atherogenic dyslipidemia , raised blood press...
this study aimed to estimate nationwide prevalence of the metabolic syndrome and to identify its association with cardiovascular diseases . the data on a national representative sample of 6,147 adults from 1998 korea national health and nutrition survey were analyzed . the syndrome was determined according to two kin...
the cryoprotective effect of glycerol has been established for over six decades , since polge et al . discovered that fowl spermatozoa frozen to 79 or 192 c in media containing glycerol resumed almost complete motility upon thawing . glycerol is a small , poly - hydroxylated solute that is highly soluble ...
protectants which are cell membrane permeable , such as glycerol , have been used effectively in the cryopreservation field for a number of decades , for both slow cooling and vitrification applications . in the latter case , the glass transition temperature ( tg ) of the vitrification composition is key to i...
electrocardiograph ( ecg ) interpretation is a vital component of emergency medicine ( em ) resident education , but few studies have formally examined ecg teaching methods used in residency training . recently , the council of em residency directors ( cord ) developed an internet database of 395 ecgs that have been ...
objectives : electrocardiograph ( ecg ) interpretation is a vital component of emergency medicine ( em ) resident education , but few studies have formally examined ecg teaching methods used in residency training . recently , the council of em residency directors ( cord ) developed an internet database of 395 ecgs th...
in recent years , one - dimensional ( 1d ) nanostructured materials have attracted great interest due to their superior performance in applications such as electronics , optoelectronics , energy storage and conversion , sensing and drug delivery . up to now , lots of approaches have been reported to synthesize 1d nan...
hematite ( -fe2o3 ) and magnetite ( fe3o4 ) nanowires with the diameter of about 100 nm and the length of tens of micrometers have been selectively synthesized by a microemulsion - based method in combination of the calcinations under different atmosphere . the effects of the precursors , annealing temperature , and ...
alzheimer 's disease ( ad ) represents a complex class of debilitating brain diseases that mostly affects people aged 65 and older . ad is characterized by progressive loss of neurons in the hippocampus and cortex , which results in the shrinkage of brain . basically , the brain cells required to process , store an...
alzheimer 's disease ( ad ) , a fatal progressive neurodegenerative disorder , has no cure to date . one of the causes of ad is the accumulation of amyloid - beta 42 ( a42 ) plaques , which result in the onset of neurodegeneration . it is not known how these plaques trigger the onset of neurodegeneration . there ...
benign and malignant peripheral nerve sheath tumors may occur sporadically or in conjunction with neurofibromatosis type 1 . malignant peripheral nerve sheath tumors ( mpnsts ) are rare , aggressive soft tissue sarcomas that either arise from a peripheral nerve or show nerve sheath differentiation . up to 11% may ari...
introduction . malignant peripheral nerve sheath tumors ( mpnsts ) are rare , aggressive soft tissue sarcomas associated with poor prognosis , that most commonly affect patients aged 20 to 50 years , but have also been reported in children . there is little reported in literature on these tumors in africa . mater...
the morbidity and mortality associated with extreme heat events such as those in chicago in 1995 , europe in 2003 [ 24 ] , and california in 2006 underscore the potential impact of heat on population health . preparing for extreme heat events and monitoring their impact is therefore important to public health ...
this paper compares syndromic surveillance and predictive weather - based models for estimating emergency department ( ed ) visits for heat - related illness ( hri ) . a retrospective time - series analysis of weather station observations and icd - coded hri ed visits to ten hospitals in south eastern ontario , canad...
-adrenoceptor ( ar ) antagonists were first used in the urologic field to treat patients with lower urinary tract symptoms suggestive of benign prostate hyperplasia ( bph ) . subsequently , many trials have provided evidence of the efficacy and tolerability of -ar antagonists in male patients with lower urinary tract s...
we evaluated the therapeutic effects of tamsulosin for women with non - neurogenic voiding dysfunction . women who had voiding dysfunctions for at least 3 months were included . inclusion criteria were age 18 yr , international prostate symptom score ( ipss ) of 15 , and maximum flow rate ( qmax ) of 12 ml / sec an...
self - assembled semiconductor quantum dots ( qds ) are currently deeply investigated because of their fundamental optical properties and their potential implementation as the active region of high - performance semiconductor lasers [ 1 - 3 ] and high - efficiency infrared detectors . details of carrier relaxation pr...
we have investigated the ultra - fast carrier dynamics in molecular beam epitaxy ( mbe)-grown inas / ingaas / gaas quantum dots ( qds ) emitting at 1.3 m by time resolved photoluminescence ( trpl ) upconversion measurements with a time resolution of about 200 fs . changing the detection energies in the spectral region ...
tea ( camellia sinensis ) consumption is rooted in medicinal use in china five thousand years ago . since then , it has become the world 's most popular drink ( after water ) , whose industry employs more than 13 million people around the world . the tea crop has rather specific agroclimatic requirements that are o...
biogenic amines ( bas ) , that is , spermine , spermidine , putrescine , histamine , tyramine , -phenylethylamine , cadaverine , and serotonin , have been determined in several samples of tea leaves , tea infusions , and tea drinks by lc - uv method after derivatization with dansyl chloride . different extraction sol...
the ultimate goal of periodontal therapy has been the regeneration of the supporting tissues lost as a consequence of inflammatory periodontal disease . this implies the formation of a new connective tissue attachment , i.e. new cementum with inserting collagen fibers , at previously diseased ( denuded ) root surface...
periodontitis is a relatively common disease . various therapies have been recommended for its treatment which includes nonsurgical , antimicrobial , and surgical therapy . in recent years lasers have been used for all the three above - mentioned purposes . lasers have been applied for hard and soft tissue debrid...
spinal muscular atrophy ( sma ) is an autosomal recessive disease characterized by degeneration of anterior horn cells of the spinal cord leading to progressive symmetrical weakness and atrophy of the proximal muscles . in addition to classical sma types ( type 1 , 2 and 3 ) a new form of sma called type 0 with intra...
spinal muscular atrophy ( sma ) is an autosomal recessive neuromuscular disease characterized by degeneration of alpha motor neurons in the spinal cord , resulting in progressive proximal muscle weakness and paralysis . in addition to the three classical sma types , a new form known as type 0 with intrauterine onset ...
boron ( b ) is a critical micronutrient in the growth of plant , which was undoubtedly considered as a part of the structure in the cell wall [ 13 ] . more increasing evidence was present for a possible role of b in metabolism processes , such as the maintenance of plasma membrane function and several metabolic pathw...
knowledge of boron and its isotope in plants is useful to better understand the transposition and translocation of boron within plant , the geochemical behavior in the interface between soil and plant , and the biogeochemical cycle of boron . it is critical to develop a useful method to separate boron from the plant ...
mri - guided focused ultrasound ( mrgfus ) is a noninvasive method of thermal ablation , which , through mri guidance , allows for 3d treatment planning and feedback of temperature deposition in the area to be treated . obstruction in the near - field of the focused ultrasound beam , such as from an ostomy bag , or i...
we present a case of successful magnetic resonance imaging - guided focused ultrasound surgery ( mrgfus ) of a uterine fibroid in a patient with extensive anterior abdominal wall surgical scars from two longitudinal laparotomies , a total colectomy and ileostomy . this case demonstrates that mrgfus can be safely us...
intravesical instillation of bacillus calmette - gurin ( bcg ) is an important adjunct to transurethral resection of bladder tumor in patients with superficial disease to reduce the risk of recurrence and progression . bcg is used in patients with stage t1 tumors , carcinoma in situ or stage ta tumors of high grade ....
bacillus calmette - guerin ( bcg ) is considered the most effective adjunctive treatment available to treat superficial bladder carcinoma . although bcg is well tolerated by most patients , it may be associated with adverse effects . one of these is bcg granulomas in the kidney . we herein report a case of a 52-y...
current understanding of central and supraspinal mechanisms for the induction and maintenance of chronic pain after sci suggests a major role for the hypofunction of serotonergic ( 5ht ) inhibitory systems [ 24 ] . sci also leads to the loss of descending serotonergic excitatory inputs caudal to the lesion site and...
transplant of cells which make biologic agents that can modulate the sensory and motor responses after spinal cord injury ( sci ) would be useful to treat pain and paralysis . to address this need for clinically useful human cells , a unique neuronal cell line that synthesizes and secretes / releases the neurotransmitt...
plants have been considered as valuable sources of medicines for treating a variety of diseases and ailments . despite the availability of modern medicine throughout all countries , previous experimental results , which were highly encouraging , revealed wattakaka ( w. ) volubilis to be a medicinal member of the fami...
objectives : the present study investigated the toxic properties of petroleum ether extract of wattakaka ( w. ) volubilis in wistar female rats.methods:an in vitro brine shrimp lethality bioassay was studied in a. salina nauplii , and the lethality concentrations were assessed for petroleum ether extract of w. volubili...
water is extremely essential for the survival of all living organisms . like many other developing countries , pakistan is also regarded as a water - stressed country , and it is likely to have a water scarcity in the near future [ 1 , 2 ] . the quality and quantity of fresh water is deteriorated by the discharge of ...
the current research was focused mainly on the designing and construction of efficient laboratory scale hybrid constructed wetland ( hcw ) for the treatment of domestic wastewater . parameters like cod , bod5 , po4 , so4 , no3 , no2 , and pathogenic indicator microbes were monitored after hydraulic retention time ( h...
a favorable macro - economic situation has been broadly considered to make positive effects on improving population health conditions . this hypothesis has been supported by previous studies with data from developed countries ( 1 , 2 ) . however , in recent study , also with the data from developed countries , it pro...
abstractbackgroundthe aim of the study was to estimate the short - run and long - run effects of unemployment rate on health outcomes of chinese population , which is under studied before.methodsthe chinese aggregate data was analyzed ( provincial data from 1990 - 2011 ) . the fixed effect model and infinite distribu...
nonalcoholic fatty liver disease ( nafld ) , defined as the presence of hepatic steatosis in the absence of alcohol use and other causes of liver disease , has become one of the most prevalent liver diseases worldwide . it represents a spectrum of conditions from simple steatosis to nonalcoholic steatohepatitis ( nas...
across - sectional study was performed in 541 type 2 diabetic patients to determine the relationship between serum uric acid ( sua ) and nafld in type 2 diabetic patients . clinical parameters including sua were determined and nafld was diagnosed by ultrasonography . sua was significantly higher in type 2 diabetic ...
the microtubules , formed by the polyerization of the cellular protein tubulin , play a crucial role in the cell division process hence any interference in the function of this protein can result in cell separation disruption and causes cellular death by apoptosis which can be used as a cancer treatment modality . a ...
eribulin is a synthetic microtubule dynamics inhibitor that was developed from a marine natural product halichondrin b. it exhibited in vitro and in vivo activities against a wide number of malignancies . a number of advanced phase trials showed improved survival following eribulin treatment in pretreated advanced br...
bisphenol a ( bpa ) is the monomer component of polycarbonate plastics and epoxy resins ; human exposure derives from leachate in foodstuffs packaged in certain plastics or from epoxy - based dental appliances . bpa stimulates prolactin secretion in fischer 344 ( f344 ) rats but not in sprague - dawley ( s - d ) rats...
acute myeloid leukemia ( aml ) is a clonal , hematological malignancy of myeloid progenitor cells . these progenitor blast cells accumulate in the bone marrow and peripheral blood , eventually disrupting normal hematopoiesis and leading clinically to anemia , neutropenia and thrombocytopenia . the prognosis for aml...
acute myeloid leukemia ( aml ) is a hematological malignancy of myeloid progenitor cells that disrupt normal hematopoiesis . current chemotherapy regimens result in complete remission in many cases ; however , there exists no standard efficacious therapy for refractory acute myeloid leukemia . the hypomethylating a...
adrenocortical carcinoma ( acc ) is a rare tumor , even rarer during pregnancy and has extremely poor prognosis both for mother and fetus . in pregnancy the most common clinical presentation , maternal and fetal complication of acc is cushing 's syndrome ( cs ) with virilization , hypertension , and prematurity . h...
adrenocortical carcinoma is a rare disease . additionally , in the case of coexisting pregnancy , there are diagnostic difficulties due to associated physiological hormonal changes as well as imaging limitations . cushing 's syndrome and virilization during pregnancy is a rare entity with few cases reported in the ...
according to worldwide estimates , hypertension affects approximately 1 billion people , resulting in 7.1 million attributed deaths per year . in the united states , nearly half of all adults have blood pressure ( bp ) , expressed in terms of systolic ( sbp ) over diastolic blood pressure ( dbp ) , in the prehyperten...
meditation techniques are increasingly popular practices that may be useful in preventing or reducing elevated blood pressure . we reviewed landmark studies and recent literature concerning the use of meditation for reducing blood pressure in pre - hypertensive and hypertensive individuals . we sought to highlight ...
pelvic fractures are high energy injuries that constitute a major cause of death in trauma patients . according to the centers for disease control and prevention ( cdc ) , trauma injury kills more people between the ages of 1 and 44 than any other disease or illness . among different types of trauma with a high impac...
fracture detection in pelvic bones is vital for patient diagnostic decisions and treatment planning in traumatic pelvic injuries . manual detection of bone fracture from computed tomography ( ct ) images is very challenging due to low resolution of the images and the complex pelvic structures . automated fracture d...
the problem of counterfeiting of drugs is assuming alarming proportions and is getting difficult to combat due to its trans - national character . therefore , there is a need to adopt zero tolerance approach to combat the problem . there are many solutions available which are being adopted in piece meal manner by i...
introduction : the problem of counterfeiting of drugs is assuming alarming proportions and is getting difficult to combat due to its trans - national character . it is undermining the faith of people on health care system . therefore , there is a need to adopt zero tolerance approach to combat the problem.the way for...
an octree is a tree data structure that recursively and adaptively subdivides the 3d space into octants , and is often used as a container for cartesian space data . here , we use octrees to store all atomic centers ( or 3d atomic cartesian coordinates ) of a molecular system , organized recursively based on ...
molecular mechanics and dynamics simulations use distance based cutoff approximations for faster computation of pairwise van der waals and electrostatic energy terms . these approximations traditionally use a precalculated and periodically updated list of interacting atom pairs , known as the nonbonded nei...
myopia affects about 25% of the adult population in the united states ( curtin 1970 , 1985 ; leibowitz et al 1980 ; burton 1990 ; katz et al 1997 ) and is considered a significant public health problem , especially in asian populations such as chinese and indians . japan has one of the highest rates of myopia in the ...
although a myopia susceptibility gene has not yet been elucidated , ten candidate regions ( myp1myp10 ) have been associated with myopia by linkage analysis employing large pedigrees . we report herein on the results of our analysis pertaining to polymorphisms of lama1 ( alpha subunit of laminin ) , a promising candi...
it describes the uneven distribution of population groups defined by a special characteristic among the subunits of a social space . population groups can be defined as subgroups of race / ethnicity , socioeconomic status , education , gender , age , etc . , social space can be a geographic social space like city ,...
background : measures of segregation are essential tools for evaluation of social equality . they describe complex structural patterns by single quantities and allow the comparison of inequalities over time or between residential places . in many countries , patterns of residential segregation are well described ( ...
in poland , colon neoplasm comes second in ranking of mortality and morbidity caused by malignancies . rectal and sigmoid cancer stands for about 70% of colon cancer . in 2003 in poland 5457 patients were diagnosed with rectal and recto - sigmoid cancer , and 2435 deaths were noted . in primary rectal cancer approx...
purposepatients with locally advanced and recurrent rectal cancer have a dismal prognosis . the aim of proposed combined therapy surgery and intraoperative brachytherapy , is to improve results of already applied methods and to define optimal group of patients for this treatment . we introduce practical experience...
it is well - known that herpes simplex virus type 1 ( hsv-1 ) is the primary infectious cause of blindness in the united states . while hsv-1 infects corneal epithelial cells , disease presentation as herpetic stromal keratitis ( hsk ) is predominantly driven by immune responses to the replicating virus , particularl...
abstractin a recent mbio article , y. jiang , x. yin , p. m. stuart , and d. a. lieb [ mbio 6(6):e01426 - 15 , 2015 , doi:10.1128/mbio.01426 - 15 ] presented an elegant set of experiments that utilized a transgenic , knockout strain of mice whose dendritic cells ( dcs ) are incapable of undergoing autophagy , to dissec...
extracellular nucleotides are released during different processes including exocytosis ( e.g. , platelets ) , shear stress ( e.g. , red blood cells ) , cell activation ( e.g. , platelets , endothelial cells ) , and cell lysis [ 1 , 2 ] . once released the effect of nucleotides is exerted via the activation of several s...
nucleoside triphosphate diphosphohydrolase-1 ( ntpdase1 ) , like other ectonucleotidases , controls extracellular nucleotide levels and consequently their ( patho)physiological responses such as in thrombosis , inflammation , and cancer . selective ntpdase1 inhibitors would therefore be very useful . we previously ...
the most important epidemic disease in aged adults of the 21 century is diabetes , particularly in asian developing countries . the overall prevalence of type 2 diabetes in isfahan , a centrally located city in iran with a population of almost two million ( 1,986,542 in 2006 ( men 1,017,940 ) ) , was reported as high...
objective : low testosterone , with or without symptoms , reported in diabetic men in some studies . we investigated the prevalence of hypogonadism in iranian type 2 diabetic men.materials and methods : total testosterone ( tt ) and sex hormone binding globulin ( shbg ) concentrations were measured in 247 diabetic me...
hirsutism , defined as thick male patterned hair in females , affects 5%10% of females.1 treatment of hirsutism imposes high costs to patients . most systematic treatments of hirsutism include anti - androgens , and although a lack of high levels of androgen can be helpful , this treatment has side effects , and its ...
hirsutism is a common problem in dermatology that imposes high socioeconomical costs on medical care . consequently , researchers are actively searching for cheaper and safer methods for therapeutic treatment . the objective of the present study is to evaluate formic oil , enriched from formic acid , for the remova...
vesicoureteral reflux ( vur ) is a common abnormality of the urinary tract in childhood . diagnostic imaging of vur is one of the most frequently used procedures in pediatric radiology departments all over the world . voiding cystourethrography ( vcug ) and radionuclide voiding cystography ( rnc ) are most commonly...
background : vesicoureteral reflux ( vur ) is a common abnormality of the urinary tract in childhood.objectives:as urine enters the ureters and renal pelvis during voiding in vesicoureteral reflux ( vur ) , we hypothesized that change in body water composition before and after voiding may be less different in children ...
plasmodium vivax is the most prevalent species and accounts for 85% of the cases [ 1 , 2 ] . most of the cases are characterized by a low parasite density with mild or even absent signs and symptoms of the disease [ 25 ] . however , several laboratorial abnormalities occur in the course of the infection , such as a...
background . changes in lipid profile are commonly reported in adult patients with malaria . however , a few studies evaluated lipid abnormalities in children continuously exposed to p. vivax . objective . to evaluate lipid abnormalities in children with p. vivax infection and to assess if parasite count or the history...
both age and diabetes mellitus ( dm ) are independent prognostic predictors of hospital mortality in acute coronary syndrome ( acs ) . an analysis on the in - hospital events and 6 months outcomes in elderly patients with acs who were included in the grace registry showed that the more elderly , the higher risk are t...
background and purpose : elderly diabetics ( dm ) who present with acute coronary syndrome ( acs ) constitute a very high risk group . we present the pattern of management of elderly patients ( > 65 years ) in the kingdom of saudi arabia ( ksa ) in comparison to the international data extrapolated from a multicenter ...
eating disorders are defined in the diagnostic and statistical manual of mental disorders ( 5 ed . ; dsm-5 ; american psychiatric association , 2013 ) into 4 categories : bulimia nervosa , anorexia nervosa , binge eating disorder and other specified feeding or eating disorders . although eating disorders only affect ...
background and aimspast research has examined eating disorder risk among college students majoring in nutrition and has suggested an increased risk , while other studies contradict these results . exercise science majors , however , have yet to be fully examined regarding their risk for eating disorders and exercise ...
pneumoconiosis was first reported in korea as an occupational disease in 1954 and accounted for 72.7% of occupational diseases detected among active workers in 1987 by the special health examination . since then , the number of active workers with coal workers ' pneumoconiosis ( cwp ) has fallen since the coal mining i...
this study identifies the number of pneumoconiosis patients after eliminating deceased patients between 2003 and 2008 as of january 1st and estimates it for the next five years . from 2003 to 2008 , the pneumoconiosis patients were 16,929 , 17,224 , 17,366 , 17,566 , 17,542 , and 17,546 , respectively . the number of...
this prospective , control versus intervention group clinical trial was conducted in the general medicine department of a 550 bedded multi specialty tertiary care teaching hospital , located at coimbatore , in the south of india from may 2009 through december 2009 ( 8 months ) . the main endpoint outcome of this stud...
background : diabetes mellitus has become an international healthcare crisis that requires new approaches to prevent and treat it . the objective of this study was to evaluate the impact of pharmaceutical care on quality of life ( qol ) in patients with type 2 diabetes mellitus.methods:a prospective study on impact o...
the significance of doppler ultrasound in evaluating pregnancies that have the risk for preeclampsia , intrauterine growth restriction , fetal anaemia , and umbilical cord abnormalities has become indispensable . recent findings aided in timing delivery of severely growth - restricted fetuses by promoting the use of ...
background : the objective was to determine the effectiveness of doppler velocimetry results in the management of high - risk pregnancy.materials and methods : this cohort study was conducted from january 2005 to december 2006 in obstetrics and gynecology department of alnoor specialist hospital , makkah , saudi arabia...
as drug discovery programs have come to rely on high - throughput screenings of diverse chemical libraries , the ability to rapidly construct complex , heterocyclic small molecules from simple starting materials is of great importance . the n , o - acetal moiety can be found in a diverse set of natural prod...
cyclic secondary amines and 2-hydroxybenzaldehydes or related ketones react to furnish benzo[e][1,3]oxazine structures in generally good yields . this overall redox - neutral amine -c h functionalization features a combined reductive n - alkylation / oxidative -functionalization and is catalyzed by acetic...
twenty - five years have passed since marc jeannerod used the simple behavior of grasping objects to create a model system for understanding goal - oriented action ( jeannerod 1984 ) . by carefully documenting the detailed kinematics of a constrained yet ecologically robust behavior , his laboratory was able to decom...
prehension , the capacity to reach and grasp , is the key behavior that allows humans to change their environment . it continues to serve as a remarkable experimental test case for probing the cognitive architecture of goal - oriented action . this review focuses on recent experimental evidence that enhances or mod...
a swelling on the left arm of a 5-year - old girl diagnosed as common b all with a lower risk group who was hospitalized for an induction therapy ( protocol # : all ic bfm-2009 ) attracted our attention . her physical examination revealed an irritable patient with a moderate health state , and an open state of consci...
trombosis is seen in children with acute lymphoblastic leukemia during or after l - asparaginase treatment . posterior reversible encephalopathy syndrome ( pres ) is a complex syndrome characterized with sudden hypertension , headache , nausea , vomiting , alteration in the state of consciousness , vision defect and ...
the differential diagnosis of sbo is a lot including primary volvulus , hernias , adhesions , bands , intussusceptions and intestinal knotting [ 2 , 3 ] . several types of intestinal knotting are reported in the literature including ileo - sigmoid knotting [ 37 ] , which is the commonest form of intestinal knotting ....
small bowel obstruction ( sbo ) is one of the most common acute surgical conditions that require urgent evaluation and treatment . several common causes are known in the general surgical practice , and the causes are different in the developing and developed world . in this article , we present a case of an acute sbo...
in the middle of the 20th century , the case of an amnesic patient shed light on the role of the hippocampus in forming and organizing newly acquired memory of facts and events , namely declarative memory . following a surgical ablation of his medial temporal lobe , henry molaison , better known as patient hm , had his...
numerous studies have implicated the hippocampus in the encoding and storage of declarative and spatial memories . several models have considered the hippocampus and its distinct subfields to contain homogeneous pyramidal cell populations . yet , recent studies have led to a consensus that the dorso - ventral and pro...
heart failure ( hf ) is a major and growing public health and clinical problem in the united states and other industrialized nations.1,2 despite advances in the medical and nonpharmacologic management of patients with acute and chronic manifestations of hf , the prognosis of patients with hf remains poor.38 given the a...
backgrounddespite the magnitude and impact of heart failure ( hf ) in the united states , relatively little data are available that describe the prognosis associated with acute hf , especially from the perspective of a population - based investigation . the purpose of this nonconcurrent prospective study was to descr...
different therapy strategies are used to reduce spasticity in patients with traumatic spinal cord lesions . these options consist of conservative management , including physiotherapeutic and pharmacological approaches , as well as surgical techniques . botulinum toxin plays an important role in the treatment of spa...
objectives : the purpose of this study was to determine the effect of botulinum toxin injections for the treatment of spasticity after traumatic spinal cord injury . methods : 9 patients were included in this prospective designed study , with a follow - up of at least 2 years . all patients suffered from a massive ...
the world health organization estimates that 8 million new cases and 3 million deaths are directly attributed to the disease each year . it is one of the leading causes of death in the world from a single infectious agent . the disease affects 2 billion people which is equal to one - third of the entire world popul...
background : although the prevalence of suspected tuberculosis ( tb ) in the kingdom of saudi arabia remains high , there has been a modest decrease in recent years . in this multi - center cross - sectional study , the prevalence of tb was determined by various techniques with the aim of identifying differences and ...
urolithiasis ( ul ) in pediatric patients is relatively rare , and the prevalence in children varies from 2 to 2.7% . several factors predispose children to developing ul , and metabolic and genitourinary abnormalities are particularly important ; these are often associated with diet , environmental factors , and inf...
purposewe investigated the influence of overweight on 24-hour urine chemistry studies and recurrent urolithiasis ( ul ) in children.materials and methodsa retrospective cohort study was designed to assess children who presented with ul at a pediatric institution between 1985 and 2010 . we calculated body mass index p...
in neurons histamine is synthesized through decarboxylation of l - histidine by a specific histidine decarboxylase ( e.c.4.1.1.22 ; hdc ) ( green et al . , 1987 ) . in a comparable manner to the architecture of noradrenergic , dopaminergic , and serotonergic systems ( mason and fibiger , 1979 ; jacobs and azmitia , 199...
histamine axons originate from a single source , the tuberomamillary nucleus ( tmn ) of the posterior hypothalamus , to innervate almost all central nervous system ( cns ) regions . this feature , a compact cell group with widely distributed fibers , resembles that of other amine systems , such as noradrenaline or se...
use of elastic stockings is one of the main clinical approaches to the treatment of venous edema and lymphedema [ 1 , 2 ] . the pressures introduced by compression hosiery , muscle activity , the environmental temperature , and the integrity of joint mobility are factors that can interfere in reductions in edema and in...
the objective of the present study was to evaluate the effect of elastic compression stockings on volumetric variations of lymphedematous limbs between mechanical lymph drainage sessions . eleven patients with grade ii leg lymphedema , regardless of etiology , were evaluated in a randomized clinical trial . the age...
a 250-ml schlenk flask , fitted with a connecting adapter attached to an argon - filled manifold , was flame - dried and charged with diene 3 ( 0.219 g , 0.298 mmol ) . after azeotropic distillation with dry benzene ( three times ; freeze - pump ) , the apparatus was charged with tungsten complex 10 ( 21.9 mg , 22.4 ...
many biologically active macrocycles contain a c c double bond through which various other derivatives are prepared ; the stereochemical identity of the alkene or the resulting moieties can be critical to the beneficial properties of such molecules . catalytic ring - closing metathesis ( rcm ) is a widely employed m...
ischemic heart disease is considered as one of the most common , serious and life threatening diseases . the prevalence of the disease is increasing all over the world and it is predicted to turn into the first cause of death by 2020 . the treatment goals in this disease include explanation for and ensuring the patie...
background : the complicated concept of quality of life ( qol ) has been considered as an important criterion for health outcomes in chronic diseases , such as heart disease , in recent years . the aim of this study was to evaluate the qol of patients with angina pectoris after treatment with enhanced external counte...
depressive disorder is a prevalent mental disorder worldwide and is also a huge burden on public health globally.1 it is a complex and heterogeneous disorder and has diverse symptomatologies and psychopathologies . common mental disorder is a diagnostic entity for nonpsychotic , depressive , and anxiety disorders . ...
objectivethere is a significant relationship between obesity and common mental symptoms ( depression and anxiety symptoms ) . but the association between depression ( or anxiety symptoms ) and serum leptin is still unclear and controversial , despite the growing body of evidence supporting the existence of leptin re...
disc herniation is one of the most common spinal diseases , and lumbar open discectomy is the most frequently used methods for treating lumbar disc herniation that requires spinal surgery4,16 ) . however , this needs an incision dissection of muscles and ligament which may cause undesirable results to lumbar spine po...
objectivepercutaneous techniques are rapidly replacing traditional open surgery . this is a randomized controlled trial study of clinical outcomes of percutaneous plasma disc coagulation therapy ( pdct ) in patients with hld(herniated lumbar disc ) as a new percutaneous access in comparison with automated percutaneou...
contour defects resulting from resection of tumors , as well as from trauma and congenital abnormalities not only affect patients cosmetically , but also may impair function , making adipose tissue restoration a strong clinical need . replace tissue with like - tissue : fatty tissue has been transplanted since 1893 ...
adipose tissue pathologies and defects have always represented a reconstructive challenge for plastic surgeons . in more recent years , several allogenic and alloplastic materials have been developed and used as fillers for soft tissue defects . however , their clinical use has been limited by further documented comp...
cubiu ( solanum sessiliflorum dunal ) , also known in spanish - speaking countries as tupiro , topiro , and cocona and known as orinoco apple and peach tomato in english - speaking countries , is a vegetable of the family solanaceae which is native to the amazon and widely distributed through the humid equa...
cubiu is a vegetable of solanaceae family , native to the amazon , which is widely distributed through brazil , peru , and colombia . it is used in food , medicine , and cosmetics by native populations . research has shown that cubiu extracts have antioxidant activities with great biological relevance . we perfor...
perforation of the bowel during placement of a biliary stent is a known complication of this procedure . we report the endoluminal loss of a biliary stent during routine stent extraction that ultimately led to a chronic colovaginal fistula . this case emphasizes the need for evaluation of fecal passage of stents in...
objectives : perforation of the bowel during placement of a biliary stent is a known complication of this procedure . we report the endoluminal loss of a biliary stent during routine stent extraction that ultimately led to a chronic colovaginal fistula . this case emphasizes the need for evaluation of fecal passage...
menopause is defined as the permanent cessation of menstrual periods that occurs naturally or is induced by surgery , chemotherapy , or radiation.1,2 the menopausal transition concludes with the final menstrual period and the beginning of postmenopause . despite its clear definition , such a transition may not be rec...
aimto examine the effectiveness of a modified relaxation ( mr ) technique in reducing blood pressure levels in thai postmenopausal women with mild hypertension , compared with a control group who received health education.methodsthis is a 16-week , randomized , parallel , open - label , controlled trial in a menopausal...
cancer represents one of the main health concerns . at the world level , 14 million of new cases were detected and 8.2 million of deaths were related to cancer in 2012 . the prevision for the next 20 years is an incidence increase of around 70 % . in spain , despite the variability in the quality of epidemiological...
purposethe spanish society of medical oncology ( seom ) has conducted a study on the access to oncologic drugs across the 17 spanish regions with the aim of identifying potential heterogeneities and making proposals for eliminating the barriers identified at the different levels.methodsan expert panel made up of medica...
bioscience was an investigatorinitiated , singleblind , multicenter , randomized noninferiority trial with minimal exclusion criteria ( clinicaltrials.gov , nct01443104 ) . the study design and the principal features of the study devices have been detailed previously.8 study enrollment was performed between februa...
backgroundno data are available on the longterm performance of ultrathin strut biodegradable polymer sirolimuseluting stents ( bpses ) . we reported 2year clinical outcomes of the bioscience ( ultrathin strut biodegradable polymer sirolimuseluting stent versus durable polymer everolimuseluting stent for percutaneous ...
the prevalence of asthma in children and adults is 3 to 38 and 2 to 12 percent , respectively . , the prevalence of asthma has increased especially in developed countries ( 1 - 3 ) . asthma is a chronic lung disease characterized by increased bronchial responsiveness , obstruction of the airways and pulmonary sympt...
objective(s ) : asthma results from the interaction between genetic and environmental factors . adam33 gene on chromosome 20p13 is associated with asthma and airway hyperresponsiveness.materials and methods : this is a case - control study , where four snps s1 ( rs3918396 ) , t1 ( rs2280091 ) , t2 ( rs2280090 ) , v4 ...
impotence and ejaculation disorders are the most common sexual diseases in men . sexual dysfunction tends to increase with age and is more common among elderly patients with comorbidities such as cardiovascular disease and diabetes mellitus ( 1 ) . pe may affect men of all age groups and does not usually occur with o...
background : premature ejaculation ( pe ) is the inability to delay ejaculation , occurring sooner than they or their partner would like during sexual activities . pe is a challenging problem that can affect sexual enjoyment and may harm relationships of couples and affect their quality of life . in idiopathic pe , s...
the primary cd8 t cell responses to acute lcmv infection were compared in mice genetically deficient in either ifn ( ) or ifnr1 ( r ) . after infection 1 a ) , consistent with earlier in vitro reports ( 13 , 14 ) , and they retained the capacity to reduce viral burden by several orders of magnitude ( unpublished dat...
interferon- ( ifn ) is important in regulating the adaptive immune response , and most current evidence suggests that it exerts a negative ( proapoptotic ) effect on cd8 + t cell responses . we have developed a novel technique of dual adoptive transfer , which allowed us to precisely compare , in normal mice , the in...
metal dyshomeostasis is known to be involved in the etiology of a number of pathologies such as wilson 's , alzheimer 's , parkinson 's , and niemann pick diseases and cancer . neurodegenerative disorders and cancer have long been viewed as among the most enigmatic and problematic issues in biomedicine , and their m...
metal dyshomeostasis is involved in several pathologies , making metal ions promising therapeutic targets . conjugating 8hydroxyquinolines with sugars gave rise to novel derivatives with improved solubility , selectivity , and multifunctionality . biological evaluation of these compounds suggests they have potentia...
scorpion envenomation is common in tropical and subtropical areas of the world including southwestern part of iran especially in khuzestan province ( prendini 2000 , shahbazzadeh et al . envenomation by h. lepturus belonging to family hemiscorpiidae is not painful and the clinical manifestations in stung patients inc...
background : envenomation by hemiscorpius lepturus is not painful and the clinical manifestations include bloody urine due to hemoglobinuria or hematuria , dermonecrotic reactions , cardiac arrhythmia and in minority of cases acute renal failure which may lead to death following disseminated intravascular coagulation i...
occupational asthma is a form of work - related asthma characterized by variable airflow obstruction , airway hyperresponsiveness , and airway inflammation attributable to a particular exposure in the workplace and not due to stimuli encountered outside the workplace . it has become the most common work - related lun...
background : the production of silk is a multidimensional and multistep process involving exposure of workers to allergens at work place . the silk allergen has been implicated in the development of bronchial asthma.objectives:to identify the prevalence of occupational asthma ( oa ) and to identify sensitization to sil...
it is now broadly recognized that microorganisms in their natural environments are most often found in surface - associated sessile communities , known as biofilms . this multicellular behavior offers the community members benefits , particularly with regard to increased resistance against environmental fluctuations ...
microorganisms in nature often live in surface - associated sessile communities , encased in a self - produced matrix , referred to as biofilms . biofilms have been well studied in bacteria but in a limited way for archaea . we have recently characterized biofilm formation in three closely related hyperthermophilic...
the human body has simple and compound organs that obtain their nourishment through four humors . one of them is bile ( yellow bile ) . according to iranian traditional medicine ( itm ) , there are various kinds of natural medicines with their specific mechanisms of action affecting on bile in the human body . ha...
background : the human body has simple and compound organs that obtain their nourishment through four humors . one of them is bile ( yellow bile ) . according to iranian traditional medicine ( itm ) , there are various kinds of natural medicines with their specific mechanisms of action affecting on bile in the huma...
rhipicephalus ( boophilus ) microplus ( canestrini , 1888 ) is a widely prevalent tick and assumes great significance in a tropical country like india , where the warm , humid climate favours its perpetuation and propagation . the cost caused by tick and tick borne diseases has not been systematically studied in indi...
rhipicephalus ( boophilus ) microplus is the most common tick species in india infesting cattle and buffaloes and causing significant economic losses to dairy and leather industries by adversely affecting the milk production and quality of hides . a study to evaluate the acaricide resistance status of rhipicephalus (...
understanding chemical reactions and reactivity is one of the central goals of chemistry and , more broadly , all natural science . the ability of molecular species to react and form new , more complex ones is responsible for the evolution and existence of the universe , earth , and biological life . in mod...
fundamental principles that determine chemical reactivity and reaction mechanisms are the very foundation of chemistry and many related fields of science . bimolecular nucleophilic substitutions ( sn2 ) are among the most common and therefore most important reaction types . in this report , we examine the tre...
ginseng has well - known , diverse actions and effects on the human body , such as nonspecific resistance to biochemical and physical stresses , and the improvement of vitality , longevity and mental capacity [ 1 - 6 ] . generally 4 to 6 years of growth are required to produce high quality ginseng roots and the culti...
in order to investigate the diversity of endophytes , fungal endophytes in panax ginseng meyer cultivated in korea were isolated and identified using internal transcribed spacer ( its ) sequences of ribosomal dna . three cultivars of 3-year - old ginseng roots ( chunpoong , yunpoong , and gumpoong ) were used to isol...
despite the increased incidence of prostate cancer over the past two decades , patient survival has improved because the widespread use of serum prostate - specific antigen ( psa ) as a diagnostic marker has enabled prostate cancer to be diagnosed at an early stage . as a result of increased surveillance , physician aw...
purposethe objective was to investigate the clinicopathological characteristics and the prognosis of prostate cancer patients affected by other primary malignancies.materials and methodsfrom 1990 to 2008 , we retrospectively reviewed the medical records of 1,317 patients who underwent radical prostatectomy ( rp ) for p...
preeclampsia is an important cause of maternal morbidity and mortality which complicates approximately 3% of all pregnancies . although several theories including abnormal placentation , cardiovascular maladaptation to pregnancy , genetic and immune mechanisms , increased systemic inflammatory response , and nutritio...
background : preeclampsia is an important cause of maternal morbidity and mortality with unclear cause . it is believed that inflammation plays an important role in the pathogenesis of preeclampsia . periodontal disease is a chronic inflammatory infectious condition which commonly involves humans . recently , chron...
scleromalacia commonly occurs after pterygium excision and results in staphyloma formation , scleral perforation , and uveal exposure . recently , there is an increasing tendency of scleral ischemic changes after pterygium surgery related to using mitomycin c for reducing the risk of recurrence [ 24 ] . when the ...
purpose . to evaluate the efficacy of autologous tenon grafting combined with conjunctival flap as a treatment for scleromalacia or scleral thinning after pterygium excision without any additional donor graft tissue . methods . twenty - six cases underwent autologous advanced tenon grafting combined with sliding or...
the complexity and diversity of cell membrane compositions suggest that lipids may bind to membrane proteins at specific sites and modulate their function . only within the past decade have structure determination techniques begun to achieve the resolution required to discern specifically bound lipids at at...
lipid molecules can bind to specific sites on integral membrane proteins , modulating their structure and function . we have undertaken coarse - grained simulations to calculate free energy profiles for glycolipids and phospholipids interacting with modulatory sites on the transmembrane helix dimer of the e...
renal cell carcinoma is a tumor that often spreads to organs with a large blood flow volume , such as the lungs , the liver , and bones . reports of clinical cases of metastasis to the gallbladder are rare , and in many of these reported cases , the metastasis is found by chance during autopsy . we treated a case o...
a 73-year - old female was operated with radical nephrectomy and cholecystectomy for renal cell carcinoma and suspected gallstones after 9 courses of sunitinib treatment . gallbladder specimen showed gallbladder metastasis originating from the renal cell carcinoma . gallbladder metastasis from renal cell carcinoma ...
tumors of the small bowel are rare . the small bowel accounts for 75 % of the length and over 90 % of the mucosal surface of the gastrointestinal tract ; however , small bowel cancers represent only 1 % to 3 % of all primary gastrointestinal malignancies 1 2 3 . the clinical presentation of small bowel ca...
background and study aims small bowel cancer is rare , accounting for < 5 % of all gastrointestinal neoplasms . capsule endoscopy has become the procedure of choice for non - invasive diagnosis of small bowel diseases . data on capsule endoscopy diagnosis of small bowel cancer are limited . the objective of t...
the incidence of vascular injury is 0.01%-0.05% and has not been reduced over the past 50 yr ( 1 ) . the most common injury during lumbar discectomy is seen in the common iliac artery , which is located immediately anterior to the l4 - 5 lumbar disc space ( 2 ) . types of vascular injury include laceration , arteri...
vascular injuries in lumbar disc surgery are serious complications which may be overlooked due to a broad range of clinical manifestations . it is important to be aware of the perioperative implications of this rare occurrence to lower mortality risk . a 20-yr - old man with a right l4 - 5 lumbar disc protrusion wa...
prolonged use of topical as well as systemic steroids produces a type of glaucoma that is very similar to chronic simple glaucoma . while elevated intraocular pressure ( iop ) is reversible , glaucomatous cupping and field defects are irreversible . the aim of this study was to analyze the variations in iop and the c...
background : long - term use of topical and systemic steroids produces secondary open - angle glaucoma similar to chronic simple glaucoma . the increased intraocular pressure [ iop ] caused by prolonged steroid therapy is reversible but the damage produced by it is irreversible.materials and methods : in this study ,...
a 78-year - old female was referred from a local clinic to wonkwang dental hospital for a cystic lesion in the left mandibular posterior region . there were no remarkable clinical findings except tooth mobility ( + + ) of the left mandibular second molar . the past medical history revealed that the patient had expe...
glandular odontogenic cyst ( goc ) is a rare , potentially aggressive jaw lesion . the common radiographic features include a well - defined radiolucency with distinct borders , presenting a uni- or multilocular appearance . a cystic lesion in the posterior mandible of a 78-year - old female was incidentally found ...
the development of environmentally compatible polymers is one of the current challenges in polymer chemistry . in this sense , epoxy resins from vegetable oils are extremely promising as environmentally friendly polymers for industrial applications because they share many of the characteristics of conventional petro ...
the evaluation of the temperature effect on the competitiveness between the amine addition and the amidation reaction in a model cure acid - catalysed reaction between the epoxidized methyl oleate ( emo ) , obtained from high oleic sunflower oil , and aniline is reported . the study was carried out analysing the kine...
an advance directive ( ad ) is an oral or written statement in which people declare their treatment preferences in the event that they lose decision - making capacity . ads are used to enhance the autonomy of patients for when they are unable to make medical decisions or express their preferences by themselves . ...
background . the goal of advance directives is to help patients retain their dignity and autonomy by making their own decisions regarding end - stage medical treatment . the purpose of this study was to examine preferences of advance directives among general population in korea . method . a descriptive cross - ...
identification and isolation of pancreatic progenitor cells generate much interest due not only to their developmental importance but also to their therapeutic potential for diabetes . however , the prospective isolation of pancreatic progenitor cells is difficult because of the lack of specific markers and a cell cult...
to isolate pancreatic progenitor cells with the surface markers of hematopoietic stem cells , the expression of stem cell antigen ( sca-1 ) and c - kit and the coexpression of them with pancreatic duodenal homeobox-1 ( pdx-1 ) , neurogenin 3 ( ngn3 ) , and insulin were examined in murine embryonic pancreas . then dif...
one of the main purposes of public health institutions is the surveillance and control of vaccine - preventable diseases . common practice for such diseases is to observe and monitor the basic reproduction number , r0 , and keeping it well below unity by means of additional vaccination of susceptible individuals i...
the purpose of this paper is to review the recent results of the authors in the area of infectious disease modeling by means of branching stochastic processes . this is a new approach involving age - dependent branching models , which turned out to be more appropriate and flexible for describing the spread of an infe...
in healthy individuals , a rhythmic sleep / wake cycle is maintained through the interaction of homeostatic and circadian mechanisms , as well as being modulated by external cues . the homeostatic process refers to an increase of sleep pressure that accumulates during wakefulness and is relieved by sleep ( borbely , ...
the circadian system is entrained to the environmental light / dark cycle via retinal photoreceptors and regulates numerous aspects of physiology and behavior , including sleep . these processes are all key factors in healthy aging showing a gradual decline with age . despite their importance , the exact mechanisms u...
dynamic knee stability is defined as the state responding to the proprioceptive feedback alerted by recurring postural instability caused by limited range of motion ( rom ) and restricted movement1 . pain and functional instability are the most common pathological conditions of the knee joint . mechanical knee ...
[ purpose ] to collect basic data for exercise programs designed to enhance functional knee and ankle joint stability based on isokinetic measurement and muscle strength evaluations in normal and impaired functional states . [ subjects and methods ] twenty - four subjects were randomly assigned to the athlete g...
a cyclodialysis cleft is the result of the separation of the longitudinal ciliary muscle fibers from scleral spur and causes an abnormal drainage pathway for the aqueous humor [ 1 , 2 ] . blunt ocular trauma has been proposed to be the most common cause , followed by iatrogenic complications [ 35 ] . if complicatio...
purpose . to propose a novel surgical method for the localization and management of traumatic cyclodialysis clefts . methods . five patients with traumatic cyclodialysis clefts who underwent the innovative surgery were retrospectively reviewed . the new method was introduced to repair a cyclodialysis cleft with t...
abstractthe chromalveolate hypothesis presents an attractively simple explanation for the presence of red algal - derived secondary plastids in 5 major eukaryotic lineages : chromista phyla , cryptophytes , haptophytes and ochrophytes ; and alveolate phyla , dinoflagellates and apicomplexans . it posits that a sing...
androgen is known to not only play essential roles in the growth and maintenance of the prostate but also be involved in the growth of prostate cancer cells . through animal experiments , lucia et al . found that prostate cancer is suppressed when androgen values in the body are reduced . in addition , many studi...
purposea great variety of studies on preoperative serum testosterone as a predictor of progression of prostate cancer have been reported recently . the purpose of this study was to investigate the relationship of preoperative serum testosterone levels in patients who underwent radical prostatectomy with prognostic fa...
to present a case of primary mixed ( clear cell and endometrioid type ) adenocarcinoma of the rectovaginal septum , probably arising from endometriosis and associated with a highly differentiated , early - stage endometrioid endometrial carcinoma . the patient underwent clinical / instrumental follow - up and a secon...
purposeto present a case of primary mixed ( clear cell and endometrioid type ) adenocarcinoma of the rectovaginal septum , probably arising from endometriosis and associated with a highly differentiated , early - stage endometrioid endometrial carcinoma . the case was managed by a minimally invasive approach and post...