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administration of blood and blood products carries the risk of post - operative bacterial infection and increased rates of recurrence in various malignancies . lower transfusion trigger , pre - operative autologous blood donation ( with or without erythropoietin ) , intraoperative red blood cell salvage , regional anae... | background and aims : transfusion of blood and blood products poses several hazards .
antifibrinolytic agents are used to reduce perioperative blood loss .
we decided to assess the effect of tranexamic acid ( ta ) on blood loss and the need for transfusion in head and neck cancer surgery.methods:after institutional... |
multiple myeloma ( mm ) is the second most common hematologic neoplasm that is characterized by a malignant expansion of monoclonal plasma cells in the bone marrow often accompanied with osteolytic lesions , renal failure , anemia , and hypercalcemia .
although mm currently remains an incurable malignancy , with the ... | background : lenalidomide has emerged as an important treatment for patients with multiple myeloma ( mm ) . however , its role in the management of mm is still controversial and requires further clarification .
the aim of this study was to evaluate efficacy and safety of lenalidomide for mm using a meta-analysis.meth... |
higher hemoglobin a1c ( hba1c ) has been associated with an increased risk of cardiovascular morbidity among individuals without diabetes ( 13 ) .
a potential pathway linking hba1c and cardiovascular events involves the development and progression of subclinical atherosclerosis .
the atherosclerotic process begins ... | objectivehigher levels of hemoglobin a1c ( hba1c ) are associated with increased cardiovascular disease risk among individuals without diabetes and may also be positively associated with coronary artery calcification ( cac ) .
this study investigated the association of hba1c with cac progression in the coronary arter... |
the online version of this article ( doi:10.1007/s12471 - 011 - 0198-x ) contains supplementary material , which is available to authorized users .
aortic coarctation is a congenital cardiovascular malformation comprising a circumscript narrowing of the aortic lumen usually located distally of the left subclavian art... | aortic coarctation is a common congenital cardiac defect , which can be diagnosed over a wide range of ages and with varying degrees of severity .
we present two cases of patients diagnosed with aortic coarctation in adulthood .
both patients were treated by an endovascular approach .
these cases demonstrate the ... |
malignant pleural mesothelioma ( mpm ) is a relatively uncommon malignancy arising from the pleura of the lung . in the united states , incidence in 2011
exposure to asbestos is the major risk factor in developing mpm , and there is often a lag - time of many decades between asbestos exposure and development of the d... | introduction . malignant pleural mesothelioma ( mpm )
is associated with a poor prognosis .
palliative platinum - based chemotherapy may help to improve symptoms and prolong life .
since 2004 , the platinum is commonly partnered with a folate antimetabolite .
we performed a review investigating if survival had ... |
point - of - care ultrasound ( poc us ) involves a bedside ultrasound examination performed by the attending physician who is not a specialist in radiology / sonography and who can draw conclusions concerning further management based on the outcome of the examination .
poc us uses simplified protocols ( e.g. fast fo... | the presented case of a patient in cardiogenic shock in the course of aortic dissection with concomitant cerebral circulation illustrates the effectiveness of sonography in the intensive care unit as a tool that aids the diagnostic process .
point - of - care sonography involves ultrasound assessment performed by the... |
the neuropathology of alzheimer 's disease ( ad ) was discovered by alois alzheimer over a century ago and the amyloid hypothesis was proposed twenty years ago but the molecular pathogenesis still needs to be clarified . in particular
genetic and molecular studies have confirmed the central role of amyloid- oligome... | genetic and molecular studies have confirmed the central role of amyloid- production and fibrillation in the pathogenesis of alzheimer 's disease ( ad ) .
however , the pathological pathways from amyloid- peptide oligomerization to the major pathological hallmarks of ad , such as neurofibrillary tangles , inflammatio... |
the search for new antimicrobials becomes more important because of the increasing resistance of pathogenic microorganisms .
however , the decrease of the development of the antibacterial drugs has been reported , due to the abandonment and reduction of research and difficulty in isolating novel compounds which can c... | modern techniques involving molecular biology , such as metagenomics , have the advantage of exploiting a higher number of microorganisms ; however , classic isolation and culture methods used to obtain antimicrobials continue to be promising , especially in the isolation of actinobacteria , which are responsible for t... |
the postoperative hypoxemia seen in obese patients is often secondary to respiratory dysfunction with an increase in the ventilation - perfusion mismatch .
in addition , other causes of postoperative hypoxemia , such as pulmonary embolism with a reported incidence of 600,000 per year in the united states , are also c... | postoperative hypoxemia can be a challenging diagnostic and management dilemma for the clinician .
we present here a case of postoperative hypoxemia following laparoscopic gastric bypass surgery secondary to presumed pulmonary embolism complicated with a patent foramen ovale .
the diagnostic pitfalls associated wit... |
medicine is the only profession that labours incessantly to destroy the reason for its own existence .
sepsis and septic shock in the intensive care unit ( icu ) still contribute significantly to our workload and , unfortunately , account for significant mortality .
consequently , they continue to provide much inte... | sepsis and septic shock continue to contribute to our workload and stimulate our research activities although many fundamental questions remain .
studies reported on here focus on inotrope use and a novel way of predicting inotrope response . continuing this theme more fundamental work
is reported examining the mit... |
the genotype of m. lychnidis - dioicae used in this study was isolated from s. latifolia in lamole , italy , and haploid products of a meiosis were isolated by micromanipulation and cultured on growth medium ( as in hood and antonovics 2004 ) .
this is the same strain used in the majority of previous studies by hood ... | genomic regions that determine mating compatibility are subject to distinct evolutionary forces that can lead to a cessation of meiotic recombination and the accumulation of structural changes between members of the homologous chromosome pair .
the relatively recent discovery of dimorphic mating - type chromosomes in... |
high - risk status in prostate cancer as defined by t stage , gleason score , or presenting psa confers a high probability of extraprostatic and lymphatic spread of cancer .
radiotherapy ( rt ) in conjunction with neoadjuvant and concurrent long - term androgen suppression has been demonstrated to improve outcomes in... | purpose .
high - risk prostate cancer patients often receive radiotherapy ( rt ) to pelvic lymphatics ( pls ) . the aim of this study was to determine the safety
margin around clinical target volume for pl ( pl - ctv ) to construct planning target volume for pl ( pl - ptv ) and for planning elective pl irradiation ... |
there are many anomalies of development of thyroid gland , which include ectopia along the path of descent of thyro - glossal duct or at other places in the neck .
we have come across triple thyroid ectopia , i.e. , nodules of thyroid tissue at three places , namely base of tongue , sublingual or pre - hyoid region a... | various anomalies of thyro - glossal duct have been described , in which the duct may form a cyst or may present as a solid nodule to form an ectopic gland .
the ectopic gland can develop along the tract of the duct to give rise to ectopic lingual , sublingual ( pre - hyoid ) or sub - hyoid ( pyramidal ) gland , with... |
medicare spending for physicians ' services has been the subject of increasing discussion and congressional action in recent years .
there have been major changes to the medicare program every year since 1981 . however , the 1984 deficit reduction act was the first legislation to contain provisions , including a fee ... | medicare spending for physicians ' services , the second largest component of the medicare program ( 24.5 percent ) , represents 1.3 percent of the federal budget , 0.41 percent of the gross national product , and 19.4 percent of national spending for physicians ' services .
interest in reforming the medicare physici... |
keloid ( keloid disease ) is a mild form of skin neoplasm which appears as a result of abnormal wound healing .
it arises from the excessive accumulation of extracellular matrix in the forming scar and it often extends beyond the area of the primary skin lesion [ 15 ] .
it concerns predisposed persons in whom , as ... | keloid disease is the abnormal formation of scar tissue in genetically predisposed people . among many genes which may be related to the development of keloids ,
transforming growth factor 1 ( tgf-1 ) is one of the most mentioned .
it encodes cytokinin , which is responsible for the production of extracellular matr... |
the intrinsic stability of the hip is critical in the prevention of subluxation or frank dislocation and ensures that the integrity of the articular surfaces remains undamaged . as a ball and socket joint connecting the axial to appendicular skeleton , the hip has a strong inherent osseous stability .
this is further... | objective : the purpose of this article is to report on a distinctive pattern of linear femoral head chondral lesions that were observed in 7 patients who underwent hip arthroscopy for the treatment of mixed - type femoroacetabular impingement ( fai).design : between 2010 and 2012 , 702 patients were treated with hip a... |
the age - related eye disease study was a clinical trial that examined the impact of zinc and antioxidants on incidence and progression of amd . using areds phenotype data tables made available through the database of genotypes and phenotypes ( dbgap ) on a subset of participants in the areds , we examined subjects wit... | purposeage - related macular degeneration is a common form of vision loss affecting older adults .
the etiology of amd is multifactorial and is influenced by environmental and genetic risk factors . in this study , we examine how 19 common risk variants contribute to drusen progression , a hallmark of amd pathogenesi... |
the fetal head occiput posterior position , found in about 5% of deliveries , unlike the anterior varieties , involves different labor and delivery management . due to a higher incidence of physical and psychological traumas ,
maternal and neonatal outcomes are worse - increased rates of cesarean section ( c - sectio... | objectives : the main objective of this study was to observe the behavior of the fetal head position during labor , when starting from occiput anterior or posterior position and also to determine their importance in labor management ( if the starting fetal head position can be a strong argument in favour of vaginal or ... |
the most common leukemia associated with down syndrome is acute megakaryoblastic leukemia ( amkl ) , and the incidence is approximately 500-fold higher than in healthy children ( 1 ) .
transient myeloproliferative disorder ( tmd ) is a leukemoid reaction occurring occasionally in down syndrome newborn infants , and i... | although acquired mutations in the gata1 gene have been reported for down syndrome - related acute megakaryoblastic leukemia ( ds - amkl ) in caucasians , this is the first report of a korean down syndrome patient with amkl carrying a novel mutation of the gata1 gene .
a 3-yr - old korean girl with down syndrome was ... |
the data analyzed were case counts , population data , and distances between affected and nonaffected districts ( these distances are influential predictors in the spread of infectious diseases ) ( 35 ) .
we first classified as affected those districts within guinea ( prefectures ) , sierra leone ( districts ) , and ... | to explain the spread of the 2014 ebola epidemic in west africa , and thus help with response planning , we analyzed publicly available data .
we found that the risk for infection in an area can be predicted by case counts , population data , and distances between affected and nonaffected areas . |
one
of the main goals of synthetic biology is to use well - characterized
functional modules for engineering biological systems with novel functionalities .
these functional modules are usually protein - coding or regulatory
dna parts , which are cloned from various organisms or synthesized ,
and assembled to... | synthetic biology is a relatively
new field with the key aim of
designing and constructing biological systems with novel functionalities .
today
, synthetic biology devices are making their first steps in contributing
new solutions to a number of biomedical challenges , such as emerging
bacterial antibiotic... |
alaska native and american indian persons living in alaska are eligible for health care in a prepaid managed healthcare system through the alaska native tribal health consortium and alaska native medical center ( anmc ) , a tertiary referral hospital in anchorage .
since 1995 , the alaska native tribal health consort... | objectivestreatment with pegylated interferon and ribavirin may prevent progression of liver disease among patients with chronic hepatitis c virus infection ( hcv ) .
treatment initiation is based on published clinical eligibility criteria , patients willingness to undergo treatment and likelihood of success .
we e... |
it is estimated that close to 20% of human cancers are due to infections with known pathogens , mainly with viruses .
given the difficulties in unambiguously assigning their causative role and the fast rate of discovery of new viruses , it is likely a conservative estimate .
one of the first identified cancer - c... | viruses are considered as causative agents of a significant proportion of human cancers . while the very stringent criteria used for their classification probably lead to an underestimation , only six human viruses are currently classified as oncogenic . in this review we give a brief historical account of the discover... |
citrin , encoded by slc25a13 , is a mitochondrial inner membrane aspartate - glutamate carrier that transfers a cytosolic nadh - reducing equivalent into the mitochondria as part of the malate - aspartate shuttle in the liver , .
citrin deficiency causes neonatal intrahepatic cholestasis ( niccd : omim 603471 ) and a... | backgroundcitrin , encoded by slc25a13 , is a component of the malate - aspartate shuttle , which is the main nadh - transporting system in the liver .
citrin deficiency causes neonatal intrahepatic cholestasis ( niccd ) , which usually resolves within the first year of life . however , small numbers of adults with c... |
spinal meningiomas are the second most common tumors after schwannoma and they represent about represent 25 to 46% of spinal tumors18 ) .
although the most common calcified intradural spinal tumor is a meningioma , totally ossified cases are uncommon and account for only 1 - 5% of all spinal meningiomas2,6 ) .
a os... | a 61-year - old woman with a very rare case of totally ossified large thoracic spinal metaplastic meningioma , showing progressing myelopathy is presented .
computed tomographic images showed a large totally ossfied intradural round mass occupying the spinal canal on t9 - 10 level .
magnetic resonance imaging revea... |
optimal dose - regimen selection attempts to select a drug input profile that offers the best benefit / risk ratio for a given indication in a given population .
knowledge of the dose exposure response relationship is the key aspect for rational dose selection .
the dose exposure response relationship is driven... | the breakout session 2 of the european medicines agency / european federation of pharmaceutical industries and associations modeling and simulation ( m&s ) workshop focused on two topics : when and how m&s should be used and would be accepted by the authorities for the dose - regimen selection ; and when and how m&s ca... |
nearly 10% of patients with secundum - type asd are found to have multi - fenestrated asds ( mfasds ) .
the authors describe a case of a woman with multiple asds who was successfully treated with a single asd occluder .
the patient was a 45-year - old female who had a cerebrovascular attack ( cva ) , presenting wit... | a 45-year - old patient presented with a cerebrovascular attack and was subsequently found to have a multi - fenestrated atrial septal defect .
various therapeutic options for percutaneous transcatheter closure with their respective benefits and flaws are discussed , as well as procedural and financial considerations... |
reliable follow - up of bone mineral density ( bmd ) by dual - energy x - ray absorptiometry ( dxa ) scans is essential both in clinical practice and in medical research .
however , aging or defective dxa technology may compromise reliability of subsequent dxa measurements and , thus , require change of machinery . i... | in long - term prospective studies , dual - energy x - ray absorptiometry ( dxa ) devices need to be inevitably changed .
it is essential to assess whether systematic differences will exist between measurements with the new and old device .
a group of female volunteers ( 2172 years ) underwent anteroposterior lumba... |
in vitro cross - presentation of ova was measured by a dye dilution assay of cfse - labelled nave ot - i t cells .
ova , -al2o3- ova , anatase tio2-ova , or -fe2o3-ova were incubated with 5 10 bone marrow derived dcs for 6 hrs , washed 3 times , and co - incubated for 60 hrs with 1 10 cfse- labelled ot - i t cells ... | therapeutic cancer vaccination is an attractive immune therapy strategy to actively induce t cells that specifically recognize and kill tumour cells in cancer patients .
however , it remains difficult to generate a large number antigen - specific t cells using conventional vaccine carrier systems1,2 .
here we show ... |
the equivalent of 1 od600 of cells should produce at least 1g of total rna and a minimum of 30 g is recommended for the procedure .
resuspend cells in lysis buffer solution consisting of 0.3 m buffered na - acetate ( ph 4.5 ) and 10 mm edta .
vortex with an equal volume of na - acetate - saturated phenol / chlorofo... | trna aminoacylation , or charging , levels can rapidly change within a cell in response to the environment[1 ] .
changes in trna charging levels in both prokaryotic and eukaryotic cells lead to translational regulation which is a major cellular mechanism of stress response .
familiar examples are the stringent resp... |
endotoxemia in response to bacterial lipopolysaccharide ( lps ) is characterized by the production of inflammatory cytokines such as tumor necrosis factor alpha ( tnf- ) , interleukin 1 ( il-1 ) , and gamma interferon ( ifn- ) along with the release of highly reactive oxygen and nitrogen intermediates which are thought... | expression of innate immune receptors varies among organs and species and within different strains among the same species ; thus , periodic classification of different pattern recognition receptors in the available strains is necessary to initiate different therapeutic approaches to combat inflammation . on characteriz... |
the hippocampus is dysfunctional in schizophrenia ( weiss , 2003 ; ongr , 2006 ; ragland , 2001 ; ledoux , 2013 ; heckers , and konradi , 2010 ) .
meta - analyses have concluded that schizophrenia is associated with memory impairment ( heinrichs , and zakzanis , 1998 ; aleman , 1999 ) and that hippocampal recruitment... | hippocampal hyperactivity has been proposed as a biomarker in schizophrenia .
however , there is a debate whether the ca1 or the ca2/3 subfield is selectively affected .
we studied 15 schizophrenia patients and 15 matched healthy control subjects with 3 t steady state , gadolinium - enhanced , absolute cerebral blo... |
internationally , the appropriate use of acute hospital beds is a main concern of policy makers and hospital practitioners ( 1 ) .
health expenditures in iran constituted 5.60% of the gross national product in 2010 , and hospital expenditures increased by more than three times from 2002 to 2007 .
this occurred desp... | background : employment of utilization review instruments is a method for managing costs and efficiency in the healthcare systems.objectives:this study developed an instrument for measuring the level of inappropriate acute hospital admissions and days of care in iran.patients and methods : the american version of the a... |
pantoprazole , a proton pump inhibitor ( ppi ) , is indicated for the treatment of erosive esophagitis associated with gastroesophageal reflux disease ( gerd ) .
pantoprazole is one of the highly prescribed ppi in the management of peptic ulcer diseases .
it shows high specificity for the relevant binding sites on ... | the objective of this study was to investigate the bioequivalence of two formulations of 40 mg pantoprazole sodium enteric - coated tablets : tripepsa as the test and pantocid as the reference .
the two products were administered as a single oral dose according to a randomized two - phase crossover with a 1-month wa... |
mitochondrial complex iii in humans consists of 11 subunits , all of which are encoded by nuclear genes except for cytochrome b ( ec 1.10.2.2 ) which is encoded by mt - cyb in the mitochondrial genome .
complex iii deficiency is most commonly caused by mutations in mt - cyb or the nuclear gene bcs1l .
mutations in ... | complex iii deficiency due to a mt - cyb mutation has been reported in patients with myopathy . here
, we describe a 15-year - old boy who presented with metabolic acidosis , ketotic hypoglycemia and carnitine deficiency . electron transport chain analysis and mitochondrial dna sequencing on muscle tissue lead to the... |
gastric - banding is a well - known restrictive bariatric surgery technique that has established benefits of weight loss and reduction in metabolic and cardiovascular disease burden .
it has relatively fewer serious complications compared to other techniques such as roux - en - y gastric bypass .
band specific comp... | introductiongastric band erosion is a known complication of adjustable gastric band surgery .
there are no previous reports of gastric band erosion associated with gastric emphysema ( ge ) or emphysematous gastritis ( eg ) , a rare condition with a mortality rate exceeding 50%.presentation of casewe report the first ... |
since long ago , man has searched for restoration of esthetics and masticatory function in order to meet these requirements satisfactorily .
buonocore ( 1955 ) suggested the utilization of acids to alter the tooth surface and make resins more suitable . by thinking this way , porcelain was the material that met these... | the purpose of this article was to compare the mean value of optical density of four porcelains commonly used for fabrication of inlay / onlay prostheses using direct digital radiograph .
the sample consisted of 20 2-mm thick porcelain specimens ( measured by digital pachymeter ) : empress ( ivoclair ) , simbios ( de... |
the causes of cognitive disability vary with the severity of the condition : moderate - to - severe intellectual disability ( defined as an intelligence quotient [ iq ] score less than 50 ) is much more likely to be due to a single pathological cause ( genetic or environmental ) than mild mr ( defined as an iq score be... | the importance of genetic influences on cognitive disability has been recognized for a long time , but molecular analysis has only recently begun to yield insights into the pathogenesis of this common and disabling condition .
the availability of genome sequences has enabled the characterization of the chromosomal de... |
the vignette suggests that the philosophers s stone has been found with the introduction of sumatriptan .
subcutaneous sumatriptan 6 mg and subcutaneous naratriptan 10 mg are both highly effective drugs .
headache relief at 2 h was 81 , 8589% [ 14 ] , and 91% , respectively ; but in both cases there is a high ... | dose response curves for headaches relief and adverse events ( aes ) are presented for five triptans : sumatriptan , zolmitriptan , naratriptan , almotriptan , and frovatriptan , and the cgrp antagonist telcagepant .
the upper part of the efficacy curve of the triptans is generally flat , the so - called ceiling eff... |
the standard guidelines for perioperative management of hypertensive patients are to continue antihypertensive medications until the day of surgery .
these drugs need to be started as soon as possible after surgery as an interruption of these drugs may cause perioperative rebound hypertension , tachycardia or myocard... | background and aims : antihypertensive drugs are continued until the day of renal transplant surgery .
these are associated with increased incidence of hypotension and bradycardia .
hence , this study was designed to evaluate perioperative haemodynamic and early graft functioning in renal recipients with discontinu... |
silexan
is a patented active substance with an essential oil produced from lavandula angustifolia flowers by steam distillation .
silexan is formulated in a soft gelatin capsule containing 80 mg of lavender oil , and it has been authorized in germany as a medicinal product for the treatment of states of restlessne... | background : recently , silexan , a patented active substance comprised of an essential oil produced from lavandula angustifolia flowers , has been authorized in germany as a medicinal product for the treatment of states of restlessness related to anxious mood .
its efficacy has been shown in several forms of anxiety... |
cerebrovascular complications occur in 2040% of patients with infective endocarditis ( ie ) , . moreover , in cases complicated by intracranial hemorrhage ( ich ) , because of the high risk of postoperative neurologic deterioration due to systemic heparinization during valve surgery , current guidelines recommend that ... | highlightsoptimal timing of surgical treatment for infective endocarditis ( ie ) complicated by intracranial hemorrhage remains controversial.we believe that emergency surgery in active infective endocarditis patients with intracranial hemorrhage is justified if there are multiple indications for emergency surgery and ... |
stroke patients often have toileting problems , and once such problems occur and the
disabled individual requires toileting care , he or she may be burdened psychologically1 . if they need help with toileting , it is
hard for them to live at home2 , 3 .
therefore , establishing toileting independence is a
criti... | [ purpose ] we developed and assessed improved underpants allowing patients to easily and
completely open the crotch by pulling upward a string on the back of the underpants while
seated .
[ subjects and methods ] healthy subjects tested commercial open - crotch underpants
for disabled people and our improved o... |
infertility is a common medical problem and the male partner is contributory in half of these cases .
while conditions such as a varicocele , cryptorchidism and hypogonadism are definable causes for infertility , no cause may be determined for an abnormal semen analysis in over 25% cases .
there are very few scient... | introduction : there is insufficient scientific data on the medical management options for idiopathic oligoasthenoteratospermia ( ioats ) .
we conducted a double blind , randomized , placebo - controlled trial to assess the efficacy and safety of the herbo - mineral supplement , addyzoa , in infertile men with ioats ... |
the spinal pain syndromes are foremost among the ailments related to the motor system ; data from the literature indicate that from 60% to 80% of the european population is affected . both the variety of these ailments and their scope are significant , and often they are not spine - related .
it appears that there is... | summarybackgroundthe aim of this paper is the evaluation of effectiveness of manual therapy in the treatment of functional disturbances of the spine.material/methodsthe study subjects were 40 persons aged 4560 years , in whom degenerative changes in intervertebral discs and physical limitations within the spine were fo... |
the introduction of anti - vegf treatment has improved the quality of life of wet age - related macular degeneration ( amd ) patients.1 moreover , modern imaging equipment , including spectral domain optical coherence tomography ( sd - oct ) , has enabled us to improve our understanding about the disease itself and the... | purposethe purpose of this study was to assess whether specific characteristics of spectral domain optical coherence tomography ( sd - oct ) affect structural and functional outcomes and number of injections needed in ranibizumab ( 0.05 ml of 10 mg / ml lucentis solution)-treated wet age - related macular degeneration ... |
. however , a gap still exists between doctors and patients in understanding clinical conditions .
emergency conditions such as strokes widen this gap , as patients and their family have difficulty understanding technical terms under time constraints .
we created medical comics about subarachnoid hemorrhage and ... | abstractinformed consent has now become common in medical practice
. however , a gap still exists between doctors and patients in the understanding of clinical conditions .
we designed medical comics about subarachnoid hemorrhage and intracerebral hemorrhage to help doctors obtain informed consent intuitively ,... |
spermatogenesis is influenced by several aspects , those including metabolic , genetic , environmental and physiological factors .
quantity or quality of sperm produced , or both can be influenced in this process ( 1 ) .
this is because many sperm are never produced because of cell death during meiosis , while many... | background : the aim of the study was to assess the effect of four repeated ejaculations on the same day at two - hour intervals on conventional and functional semen parameters.methods:three healthy men ( 323.6 years ) donated the first semen samples after 34 days of sexual abstinence followed by three subsequent sampl... |
pseudomonas aeruginosa is a commonly occurring nosocomial gram - negative pathogen that is often associated with antibiotic resistant phenotypes , a profile that has been linked to therapeutic failure ( georges et al 2006 ; mesaros et al 2007 ) .
this organism can confer multiple mechanisms of resistance , including ... | while mic distributions and percent susceptibility for cefepime and ceftazidime are generally similar among pseudomonas aeruginosa , we noted an increasing discordance in susceptibility favoring ceftazidime at our hospital
. quantitative reverse transcriptase - polymerase chain reaction was utilized to explore overex... |
the subjects of this study were 51 rhesus macaque monkeys ( macaca mulatta ) , 40 female and 11 male . at the start of the study ,
their age ranged from 1.2 to 22.6 years ( median , 9.6 years ) and their weight ranged from 3.3 to 13.9 kg ( median , 5.9 kg ) .
this study was done in strict accordance with the recomm... | purposewe compare spectral - domain optical coherence tomography ( sdoct ) measurements of minimum rim width ( mrw ) , minimum rim area ( mra ) , and peripapillary retinal nerve fiber layer thickness ( rnflt ) to complete orbital optic nerve axon counts in nonhuman primates ( nhp ) with unilateral experimental glaucoma... |
different types of pesticides have been used in agricultural practice in order to enhance food production .
these pesticides differ greatly in their modes of action , uptake by the body , metabolism , elimination from the body , and toxicity to humans . among pesticides , organophosphate pesticides ( op )
although ... | background : reports have clearly indicated the role of oxidative stress in the pathogenesis of organophosphate pesticides ( op ) toxicity .
however , there is dearth of information on which group of the farm workers is more at risk of op - induced oxidative stress.aim:this study determined serum levels of malondiald... |
pneumonia is the most common infection in intensive care units ( icus ) which constitutes 31% of all nosocomial infections in these units .
ventilator- associated pneumonia ( vap ) is a common nosocomial infection among patients admitted in icus .
vap is a respiratory disease that occurs after spending more than 24... | background : oral care plays an inevitable role in health and well - being of patients in intensive care units ( icus ) .
poor oral care causes colonization of respiratory pathogens and secondary respiratory infections .
ventilator - associated pneumonia occurs in patients on mechanical ventilation for more than 48... |
the extreme elderly population , defined as patients greater than 75 years of age , is the fastest growing segment of the population . along with the aging population
comes a concomitant sharp rise in the incidence of atrial fibrillation ( af).1 ) long - term oral anticoagulation therapy is critical in the management... | background and objectivesthe prevalence of atrial fibrillation ( af ) doubles in the extreme elderly and is higher than in the rest of the population . warfarin therapy to prevent thromboembolic events secondary to af is often underutilized and under - prescribed in this subgroup , due to the fear of bleeding and other... |
granulomas are tissue reactions typically elicited by persistent , indigestible pathogens , pathogen products , or inert foreign material .
granulomas are pathologically defined by the presence of macrophage - derived epithelioid cells and giant cells , whose organization can be modified by the cells of acquired immu... | the present study was carried out to record the occurrence of naturally occurring granulomas in cattle and buffaloes .
tissues grossly suspected for granulomas were collected from 336 out of 1600 ( 21% ) abattoir cases .
the gross features ranged from focal necrosis to large caseated masses , hard nodules , growths... |
although the value of mammographic screening before age 50 and after age 74 has recently been called into question by the us preventive services task force current clinical practice guidelines recommend annual mammographic screening of all women aged 40 years or older for early detection of breast cancer .
however... | mammographically - detected breast arterial calcifications ( bac ) are considered to be an incidental finding without clinical importance since they are not associated with increased risk of breast cancer .
the goal of this article is to review existing evidence that the presence of bac on mammography correlates with... |
skin symptoms of yusho and their subsequent change were described . in the early stage ,
skin eruptions were the most prominent features of yusho .
acneform eruptions and pigmentation were most conspicuous . with the passage of time , these symptoms have improved considerably and most patients have very slight erup... | |
intravascular large b - cell lymphoma ( ivlbcl ) is an extremely rare subtype of non - hodgkin lymphoma , characterized by the presence of cd20-positive large b - cell lymphoma cells in the lumina of the small blood vessels .
the diagnosis of ivlbcl is often delayed , as it mainly presents with nonspecific symptoms ,... | intravascular large b - cell lymphoma ( ivlbcl ) is a rare subtype of non - hodgkin lymphoma .
it usually presents with nonspecific symptoms , such as fever , rather than with overt lymphadenopathy .
reports of hypercalcemia , as the initial presentation of ivlbcl , are limited in the literature , despite it being ... |
metabolomics is a new technology that applies advanced separation and detection methods to capture the collection of small molecules that characterize metabolic pathways .
this rapidly developing discipline involves the study of the total repertoire of small molecules present in the biological samples , particularly ... | metabolomics is a rapidly evolving discipline that involves the systematic study of endogenous small molecules that characterize the metabolic pathways of biological systems .
the study of metabolism at a global level has the potential to contribute significantly to biomedical research , clinical medical practice , a... |
childhood overweight and obesity is increasing worldwide [ 1 , 2 ] , and children who are overweight or obese face increased health risks such as hyperlipidemia , high cholesterol , high blood pressure , and type 2 diabetes [ 35 ] .
obesity has a long - term impact on health and research has shown that children who a... | this study explored developmental trajectory patterns of bmi and associated factors .
participants included 1,609 students who were followed from age 7 to 12 years .
data collection involved annual self - administered questionnaires and records of height and weight .
an ecological model was used to identify the f... |
schwannoma ( neurilemmoma ) is a common soft tissue tumour that occurs usually in the extremities , trunk , head and neck , mediastinum , retroperitoneum , and pelvis , but it appears to be very rare in the gastrointestinal tract . published reports mainly describe gastric schwannomas .
these tumours occur uncommonly... | schwannoma is a common soft tissue tumour , but it appears to be very rare in the gastrointestinal tract .
benign schwannoma develops extremely rarely in the mesocolon , with only 2 patients reported in the literature .
a 75-year - old woman was admitted to our department of oncological surgery with an abdominal ma... |
preserving the remaining tooth structure is a major concern in restorative dentistry . when full coverage of teeth is indicated , a reduction of dental hard tissue is necessary in order to secure structural durability and restore natural anatomy and esthetics .
the amount and geometry of the reduction should also dec... | objectives : the purpose of this in vitro study was to compare the marginal adaptation and fracture resistance of a zirconia - based all - ceramic restoration with two preparation designs.materials and methods : twenty - four mandibular premolars were randomly divided into two groups ( n=12 ) ; the conventional group r... |
chronic hepatitis c ( chc ) due to infection with hepatitis c virus ( hcv ) affects approximately 170 million people worldwide and is the most common cause of chronic liver disease .
of hcv - infected individuals , 20% to 30% eventually develop liver cirrhosis or hepatocellular carcinoma ( hcc ) .
the primary aims ... | hepatitis c virus ( hcv ) infection is a major worldwide health problem .
chronic infection induces continuous inflammation in the liver , progression of hepatic fibrosis , eventual cirrhosis , and possible hepatocellular carcinoma .
eradication of the virus is one of the most important treatment aims .
a number ... |
the national longitudinal mortality study ( nlms ) comprises us census bureau annual social and economic supplements ( march 1973 to march 2011 ) , current population surveys ( cps , february 1978 , april 1980 , august 1980 , december 1980 , and september 1985 ) , and one 1980 census cohort .
surveys gather data abou... | objective : to determine whether race / ethnicity and socioeconomic status are associated with amyotrophic lateral sclerosis ( als ) mortality in the united states.methods:the national longitudinal mortality study ( nlms ) , a united states
representative , multistage sample , collected race / ethnicity and socioecon... |
the prevalence of obesity in population of children and adolescents is still rising rapidly and it is one of the biggest public health issues in the world today [ 13 ] .
approximately today every fifth child and adolescent are obese in the us , while in europe the prevalence of obesity ranges from 5% to 31% depending... | obesity and metabolic syndrome ( ms ) are one of the biggest public health issues in child and adolescent population . to the best of the authors ' knowledge
, this hospital based study is the first report on the prevalence of ms in obese children and adolescents in dalmatia , the mediterranean part of croatia .
th... |
parasites have a profound impact on wildlife population dynamics , by having a broader effect in the ecosystem health and function and can cause temporary or permanent declines on local populations ( daszak et al . , 2000 , smith et al . , 2006 , thompson et al . , 2010
although the prevalence of parasites have be... | parasites have a profound impact on wildlife population dynamics . however ,
until some years ago , studies on the occurrence and prevalence of wildlife parasites were neglected comparatively with the studies on humans and domestic animals . in this study
, we determined the parasite prevalence of two sympatric wil... |
the anterior mitral leaflet ( aml ) cleft is an unusual congenital lesion first described in 1954 .
it results from the failure of the endocardial cushions to seal together the two components of the anterior leaflet of the mitral valve .
echocardiography is the investigative modality of choice in the evaluation of ... | a 20 year old female was referred to us for evaluation of effort dyspnoea of nyha class ii with feeble left common carotid , left brachial and left radial artery as compared to other sides .
detail evaluation with two dimensional ( 2d ) transthoracic echocardiographic , 2d transesophageal echocardiography and multide... |
degenerative disease of the mitral valve ( mv ) is the most common etiology of mitral regurgitation ( mr ) requiring surgery .
the most common finding in patients with degenerative mv disease is leaflet prolapse due to elongation or rupture of the chordae , resulting in varying degrees of mr .
degenerative mv disea... | background : mitral valve ( mv ) repair can now be carried out through small incisions with the use of robotic assistance .
previous reports have demonstrated the excellent clinical result of robotic mv repair for degenerative mitral regurgitation ( mr ) . however , there has been limited information regarding the ec... |
contact lenses are commonly used to correct refractive error and are preferred by females due to cosmetic reasons .
although generally claimed to be safe , prolonged lens wear may cause corneal hypoxia , microtrauma , and decreased turnover of corneal epithelial cells .
secondly , lens wear not only disrupts the te... | aims : prolonged contact lens wear is often accompanied by dryness of the eyes .
the aim of this study was to compare conjunctival impression cytology ( cic ) and tear film tests such as tear film break up time ( tbut ) and schirmer test for dry eye evaluation in contact lens wearers and measure their correlation wit... |
india is facing a huge burden of diabetes with 65.1 million adults diagnosed with the type 2 diabetes mellitus ( t2 dm ) in 2013 , and this figure is projected to increase to 109 million by 2035 .
the major epidemiological studies support that maintaining glycosylated hemoglobin ( hba1c ) levels as close to normal ma... | primary objective - evaluate effectiveness and safety of acarbose / metformin fixed dose fdc on glycemic control in indian t2 dm patients in real life clinical setting .
secondary objective - evaluate safety and satisfaction of treatment.materials and methods : open - label , prospective , multicentre , single - arm ... |
alkalis saponify the fatty acids in cell membranes , which results in their disruption and dissolution .
fat - soluble alkalis also have a high tissue permeability and can rapidly damage even deep areas of the tissue .
ocular injury due to an alkali burn can result in extremely serious visual impairment , depending... | a 47-year - old man presented at the ophthalmology department of saku city asama general hospital complaining of hyperemia and pain after industrial sodium hydroxide ( approx .
40% concentration ) had entered his left eye . with an epithelial defect of the bulbar and palpebral conjunctiva , ischemia of the inferior t... |
however , in clinical settings , some problems have been found in certain types of attachment used , such as early loss of rertention that leads to increase in the cost of treatment . a consensus statement from mcgill university and the british society for the study of prosthetic dentistry determined that a two - impla... | purposethis in vitro study investigated and compared the durability and retention of three types of attachments.materials and methodsthree commercially available attachments were investigated : clix , dalbo - plus and locator. in total , 72 samples of these attachments were placed in the acrylic resin forms and subject... |
a foreign body in the rectum is always a challenging diagnostic and management dilemma that begins with the initial evaluation in the emergency department and continues through the postextraction period .
usually , it is a result of pathological sexual activities performed by the patient themselves , or by other peop... | a foreign body in the rectum is not a very common surgical emergency case . in the treatment of rectal foreign bodies ,
the aim is to use the simplest possible method while protecting the integrity of the intestine .
many removal techniques have been described in the literature . here
we report a case in which a ... |
peroxisome proliferators are a chemically and structurally diverse class of chemical compounds that include phthalate esters such as di-2-ethylhexyl phthalate ( dehp ) , hypolipidemic drugs , analgesics , uricosuric drugs , and environmental pollutants . because of the commercial value of many agents that do induce per... | backgroundperoxisome proliferators are considered rodent carcinogens that are putative human non - carcinogens based on the presumed absence of direct genetic toxicity in rodent and human cells and the resistance of human cells to the induction of peroxisomes by peroxisome proliferators .
the highly sensitive lacz pl... |
kidney disease is increasing rapidly along with the increasing prevalence of hypertension and the aging of many societies worldwide . a decline in the glomerular filtration rate ( gfr ) and an increase in albuminuria , established markers of kidney function ,
have been reported to be risk factors for various diseases... | background .
the aim of this study was to clarify the relationship between the change in estimated glomerular filtration rate ( egfr ) and urinary albumin by antihypertensive treatment .
methods .
we randomized 611 treated patients with morning hypertension into either an added treatment group , for whom doxazosi... |
at present , acute appendicitis is one of the most common surgical conditions , requiring an emergency operation and accounting for 4% to 8% of all emergency department ( ed ) visits .
situs inversus totalis ( sit ) is rare congenital disease in which the thoracic and abdominal organs are transposed [ 2 - 5 ] .
the... | situs inversus totalis is a rare inherent disease in which the thoracic and abdominal organs are transposed .
symptoms of appendicitis in situs inversus ( si ) may appear in the left lower quadrant , and the diagnosis of appendicitis is very difficult .
we report a case of left - sided appendicitis diagnosed preope... |
polycystic ovarian syndrome ( pcos ) is the most common endocrinopathy , present in 15.2% of the iranian women of reproductive age , based on the rotterdam criteria .
the most commonly used definition of pcos include at least two of the three following criteria : clinical and/or biochemical signs of hyperandrogenism ... | background : the objective of this study was to investigate whether the sex hormone binding globulin ( shbg ) levels before conception are predictive of gestational diabetes mellitus ( gdm ) in women with polycystic ovarian syndrome ( pcos).materials and methods : a total of 180 women with pcos were enrolled and follow... |
with improved outcomes for patients suffering from bcr - abl fusion protein - harboring leukemias [ 1 , 2 , 3 , 4 ] , there is a growing population of patients on long - term therapy with tyrosine kinase inhibitors ( tki ) directed at the bcr - abl fusion product of the philadelphia chromosome .
while previous tkis h... | long - term therapy with tyrosine kinase inhibitors ( tki ) has resulted in improved outcomes for patients suffering from bcr - abl fusion protein - harboring leukemias . as a result , a growing population of patients on tki therapy present to their primary care providers . in this case
, we report on the case of a 6... |
proanthocyanidins ( pas ) are various length
polymers of flavanols
( catechins and their enantiomers ) linked through a single c4c8 or c4c6 bond
( b - type pas ) or with an additional c2o c7 or c2o c5 bond ( a - type
pas ) as shown in figure 1 .
there are a variety
of different classes of pas , depending ... | oligomeric
proanthocyanidins were successfully identified by uhplc - pda - hrmsn in a selection of plant - derived materials
( jujube fruit , fuji apple , fruit pericarps of litchi and mangosteen ,
dark chocolate , and grape seed and cranberry extracts ) .
the identities
of 247 proanthocyanidins were theoreti... |
drug - eluting stents ( des ) are widely used as devices of first choice in percutaneous coronary intervention ( pci ) . however , certain concerns are associated with the use of des , i.e. delayed arterial healing with a subsequent risk of neo - atherosclerosis , late stent thrombosis and hypersensitivity reactions to... | drug - eluting stents ( des ) are widely used as first choice devices in percutaneous coronary interventions . however , certain concerns are associated with the use of des , i.e. delayed arterial healing with a subsequent risk of neo - atherosclerosis , late stent thrombosis and hypersensitivity reactions to the des p... |
excessive sexual behaviors have been described and studied by clinicians and sexologists since the 19th century ( e.g. , von krafft - ebing , 1965 ) . at that time ,
excessive and uncontrolled sexual behaviors were often considered as satyriasis or don juanism in males and nymphomania in females .
initial research... | background and aimsresearch on sexual addiction flourished during the last decade , promoted by the development of an increased number of online sexual activities . despite the accumulation of studies , however , evidence collected in clinical samples of treatment - seeking people remains scarce .
the aim of this stu... |
evidence has supported the role of brain - derived neurotrophic factor ( bdnf ) in mediating the pathophysiology of depression.1 all bdnf transcripts are translated in the endoplasmic reticulum into precursor bdnf ( probdnf ) protein , which is then folded in the trans - golgi and packaged into either the constitutive ... | evidence has supported the role of brain - derived neurotrophic factor ( bdnf ) in antidepressant effect .
the precursor of bdnf ( probdnf ) often exerts opposing biological effects on mature bdnf ( mbdnf ) .
hence , the balance between probdnf and mbdnf might be critical in total neurotrophic effects , leading to ... |
sildenafil citrate ( pde -5 inhibitor ) as a vasodilator increases utero - placental blood flow and potentiates fetal growth .
in this study , a case was examined and sildenafil was administered for her . it was found that sildenafil improved the uterine blood flow with a favorable fetal outcome at delivery .
silde... | backgroundpregnancies with early onset fetal growth restriction have poor perinatal outcome .
sildenafil citrate ( pde -5 inhibitor ) as a vasodilator increases utero - placental blood flow and potentiates fetal growth.case presentationin this study , a case was examined and sildenafil was administered for her . it w... |
neoadjuvant chemoradiotherapy ( crt ) followed by total mesorectal excision ( tme ) is a standard treatment in patients with locally advanced rectal cancer .
in addition to improved local control , reduced toxicity , increased sphincter preservation , and tumor downstaging have been demonstrated after neoadjuvant crt... | purposethe aim of this study was to examine the clinical implications of a pathologically complete response after neoadjuvant chemoradiotherapy ( crt ) followed by local excision for patients with ct2 rectal cancer who refused radical surgery.materials and methodsseventeen patients with ct2 primary rectal cancer within... |
of particular importance is the occurrence of fatal toxicities in the liver where these anaesthetics are actually metabolised .
like all the other branches of medicine , anaesthesiology recently made great improvements , but the search for the ideal anaesthetic agent is still ongoing .
there are reports of postoper... | introduction : although most general anaesthesia procedures are performed without any complications , volatile agents may have adverse effects on various living systems . this study aims to compare the antioxidant effects of isoflurane and n - acetylcysteine ( nac ) on liver function.methods:forty-one patients in the a... |
clinical presentation of neonatal mesenchymal hamartoma of the liver ( mhl ) varies from incidental detection on imaging , asymptomatic mass to symptoms like abdominal distention , pain , respiratory distress , cardiac failure , anorexia , vomiting , poor weight gain , vascular steal and thrombocytopenia , intralesiona... | mesenchymal hamartoma of the liver is the second most common benign liver tumor in children .
typically , it presents as a large benign cystic , solid or mixed liver mass in a child younger than 3 years and amenable to complete resection .
we report a neonate with mesenchymal hamartoma of the liver presenting as gi... |
in 2005 , the assistant secretary for planning and evaluation ( aspe ) and cms joined together to explore both theoretically and empirically whether the use of an economywide measure of mfp growth was a reasonable proxy for use in medicare physician ratesetting .
this issue of the review is based largely on analyses ... | the following overview introduces a series of articles that focuses on multifactor productivity ( mfp ) growth in health care .
this edition of the health care financing review begins with a theoretical discussion of the medicare economic index ( mei ) and the conceptual reasons for the mfp adjustment incorporated in... |
postoperative cerebrospinal fluid ( csf ) leak is still the most serious complication of the transsphenoidal approaches to pitui tary adenoma with the rate of 0 to 27% ( 1 ) .
the csf leak predisposes the patients to life - threatening bacterial contamination that can lead to serious infections , especially meningiti... | background
proposing a strategy for sellar reconstruction in endoscopic transsphenoidal transsellar approachfor pituitary adenoma .
methods
240 patients with pituitary adenoma underwent pure endoscopic endonasal transsphenoidal surgery.intra-operative csf leaks were classified as grade 0 , no observable leak ; gr... |
monoclonal gammopathy of undeterminated significance is the most common form of plasma cell dyscrasia , usually considered as benign . in rare cases
it may have a malignant course , sometimes limited to an organ such as peripheral nerves .
we describe clinical , electrophysiological and pathological findings in a p... | abstractbackground : monoclonal gammopathy of undeterminated significance is the most common form of plasma cell dyscrasia , usually considered as benign . in rare cases it may have a malignant course , sometimes limited to an organ such as peripheral nerves.methods:we describe clinical , electrophysiological and patho... |
synthetic approaches are widely employed to observe novel phenomena in living organisms [ 1 , 2 ] , particularly in studies on species sustenance and population adaptation [ 36 ] . as a fundamental characteristic of living systems ,
adaptation is generally achieved by well - known sensing mechanisms , such as operons... | a synthetic dual - function operon with a bistable structure was designed and successfully integrated into the bacterial genome .
bistability was generated by the mutual inhibitory structure comprised of the promoters ptet and plac and the repressors laci and tetr .
dual function essential for cell growth was intro... |
pws is caused by the lack of expression of paternally inherited imprinted genes on chromosome 15q11-q13 .
, we discuss a case of pws , who presented to our out - patient department with uncontrolled diabetes .
patient was born of non - consanguineous marriage , full - term cesarean section delivery and cried normal... | prader - willi syndrome ( pws ) is a rare cause of obesity . with the rising incidence of obesity ,
clinicians need to be aware of genetic causes of obesity and when to suspect them .
a case of pws , which was diagnosed in adulthood , has been discussed .
this case is special because of lack of history of floppin... |
multidrug resistance ( mdr ) is now recognized as one of the most common causes of failure in cancer chemotherapy .
the mdr phenotype renders cross - resistance to structurally and functionally unrelated antitumor agents .
this phenomenon often causes overexpression of mdr1 gene that encodes a 170-kd transmembran... | this paper was to explore bullatacin - mediated multidrug - resistant cell apoptosis at extremely low concentration . to investigate its precise mechanisms ,
the pathway of cell apoptosis induced by bullatacin was examined .
bullatacin causes an upregulation of ros and a downregulation of m in a concentration - dep... |
the study protocol was reviewed and approved by the research ethics committees of the institute of puericulture and pediatrics martago gesteira of the federal university of rio de janeiro and the educational foundation of serra dos rgos of terespolis .
the parents of all children involved in the study gave informed c... | recently discovered respiratory viruses were detected in 19 ( 9.2% ) of 205 nasal swab specimens from children in brazil with respiratory illnesses .
five each were positive for human metapneumovirus ( hmpv ) alone and human bocavirus ( hbov ) alone , 3 for human coronaviruses ( hcov - hku1 or -nl63 ) alone , and 6 f... |
particulate air pollution caused by fine particles with aerodynamic diameters under 2.5 m ( pm2.5 ) is well known to be associated with the morbidity and mortality of cardiovascular diseases [ 1 , 2 ] .
epidemiological studies have reported that fine particulate matter is a risk factor for the mortality of cardiovas... | objective . to investigate the role of cd4+cd25 + t cells ( tregs ) in protecting fine particulate matter ( pm- ) induced inflammatory responses , and its potential mechanisms
. methods .
human umbilical vein endothelial cells ( huvecs ) were treated with graded concentrations ( 2 , 5 , 10 , 20 , and 40 g / cm2 ) ... |
gambling behavior can be defined as to put in risk something valuable , and relying on the expectation of obtaining a benefit in profit.1 gaming disorder is distinguished by gaming behaviors that seriously alter the finances , social relationships , and the occupational progress of a subject.2 gambling disorder has a l... | the present review is an overview of previous experimental work on biopsychological aspects of gambling disorder .
it includes the topics 1 ) gambling disorder from the neuroimaging and electroencephalography ( eeg ) perspective , 2 ) cognitive , executive functioning , and neuropsychological aspects of gambling diso... |
the protocol was approved by the local ethics committee , and informed consent was obtained from all participants . nine ubo women ( waist circumference > 88 cm ) and 6 lean women ( waist circumference < 80 cm ) scheduled for voluntary laparoscopic tubal occlusion were recruited .
all were nonsmokers , used no medica... | objectiveexcess visceral fat accumulation is associated with the metabolic disturbances of obesity .
differential lipid redistribution through lipoproteins may affect body fat distribution .
this is the first study to investigate vldl - triglyceride ( vldl - tg ) storage in visceral fat.research design and methodsn... |
percutaneous radiofrequency ablation ( rfa ) of liver tumors has been extensively described , and is considered safe and effective mode of treatment with minimal morbidity and mortality .
several authors have described minor and major complications as a result of rfa being between 2.2% and 9% , respectively . besides... | objectives : the aim of this study was to investigate a novel approach of using a balloon catheter as a protective device to separate liver from the diaphragm or nearby bowel during radiofrequency ablation ( rfa ) of hepatic dome tumors in an animal model.materials and methods : all experimental procedures were approve... |
this condition must always be kept in mind when a perirenal fluid collection is encountered , particularly as a bilateral presentation .
symptomatic cases are treated either by percutaneous drainage , marsupialization ( open or laparoscopic ) or by nephrectomy , depending upon the presentation .
a 23-year - old fem... | lymphangiomas are lymphatic malformations commonly seen around the neck , axillary region and the mediastinum .
perirenal lymphangiomatosis is very rare with only a few cases being reported in literature .
we present a case of symptomatic perirenal lymphangiomatosis in a female of childbearing age , managed laparos... |
a 5-year - old male presents to the emergency room with worsening constipation and stool leakage . for the past 2 months
, he had only been passing small amounts of smearing and sticky stool once every few days .
he has had no abdominal pain or vomiting , and he only had occasional discomfort with mild distention .... | background .
fecalomas are hard dense masses separate from surrounding fecal material or bowel contents .
this case report intends to provide a brief review of the literature and differential diagnosis for a pelvic mass in a pediatric patient .
case presentation .
the patient is a 5-year - old male presenting w... |
the purpose of this video is to demonstrate the use of the robot to perform a transmesocolonic pyelolithotomy of a horseshoe kidney .
ct scan imaging revealed the presence of a left horseshoe kidney with multiple pelvicalyceal stones .
a 3-arm da vinci robotic surgical system was docked , and the arms were connecte... | introduction the purpose of this video is to demonstrate the use of the robot to perform a transmesocolonic pyelolithotomy of a horseshoe kidney.materials and methods a 35-year old female presented with vague abdominal pain .
ct scan imaging revealed the presence of a left horseshoe kidney with multiple pelvicalyceal... |
fusarium is a genus of filamentous fungi spread in cereals , fruits and vegetables , water and air , and even in the soil in temperate climates .
almost all fusarium species are harmless , although some species ( fusarium solani , fusarium oxysporum , fusarium chlamydosporum and fusarium moniliforme ) produce mycotox... | fusarium infection is a severe fungal infection caused by fungi of the genus fusarium .
it most commonly occurs in immunocompromised patients with malignant hematological comorbidities or secondary to hematopoietic stem cell transplant .
the classical route of contamination is through inhalation but infection may a... |
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