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a 6 - 8 hours fasting period for solids and liquids is the traditional management in the preoperative preparation process .
prospective randomized studies demonstrated that reducing the preoperative fasting to 2 hours along with ingestion of a maltodextrin solution provides emotional and especially metabolic benefits... | abstractobjective : to evaluate the change in respiratory function and functional capacity according to the type of preoperative fasting.methods:randomized prospective clinical trial , with 92 female patients undergoing cholecystectomy by laparotomy with conventional or 2 hours shortened fasting .
the variables measu... |
neoadjuvant therapies for breast cancer allow conservative surgery in patients with large tumours and in situ evaluation of the efficacy of chemotherapy .
the response to chemotherapy is an important prognostic factor that influences surgical management and the type of postoperative chemotherapy .
a complete tumour... | the role of imaging for patients treated with neoadjuvant therapy for breast cancer is not only to evaluate the therapeutic response in terms of tumour shrinkage , but also to predict the histological response to chemotherapy , which is correlated to survival .
surgery and histopathological analysis after neoadjuvant... |
in their review , spronk and colleagues address some of the very real dilemmas faced by clinicians during the resuscitation of critically ill patients with trauma or sepsis .
having made a diagnostic judgment as to the presenting problem sepsis or trauma the clinician must next decide on the phase of resuscitatio... | resuscitation of critically ill patients with trauma or sepsis continues to challenge clinicians .
early imperatives include diagnostic judgment as to the presenting problem sepsis or trauma .
subsequently , the clinician decides on the phase of resuscitation required for support ' ebb ' versus ' flow ' . finally... |
a 40-year - old female visited our clinic for agradual visual disturbance in her right eye in january 2007 .
her best - corrected visual acuity ( bcva ) was 20/160 od and 20/20 os .
a few barely detectable creamy - yellow retinal lesions were seen in the right eye .
eighteen months prior , she had been diagnosed ... | a 40-year - old female visited our clinic for visual disturbance of the right eye , in which a few creamy - yellow retinal lesions and visual field constrictions were noted .
she had been treated for primary cns lymphoma and was in complete remission .
after failure to follow - up for three months , she lost vision... |
since self - expandable metallic stent ( sems ) placement started being covered by insurance in japan in january 2012 , sems placement has been practiced in several hospitals in japan , including ours .
the insertion of sems was performed under endoscopic and fluoroscopic guidance by endoscopists and surgeons .
wal... | self - expandable metallic stent ( sems ) placement has been practiced in several hospitals in japan , including ours , since january 2012 . here , we report the case of an 82-year - old japanese man who presented to the hospital with a 1-week history of right hypochondrial pain . computed tomography ( ct ) findings in... |
obesity is an alarming public health problem and its prevalence is increasing worldwide ( 1 ) . gastritis is inflammation of the lining of the stomach due to several causes , including h. pylori infection , which is caused by gram negative bacteria that affect the gastric mucosa ( 2 ) .
the prevalence of h. pylori in... | introductionobesity is a condition that has significant impact on public health .
recent exciting studies have linked chronic gastritis and h. pylori infection to obesity .
chronic gastritis has shown increased prevalence in obesity , more particularly h. pylori - related gastritis . this study aimed to determine t... |
in late 2002 , severe acute respiratory syndrome coronavirus ( sars - cov ) crossed the species barrier from animals to humans .
sars first struck in guangdong province , china , and was officially recognized by the world health organization ( who ) in february 2003 .
after its introduction into human populations i... | abstracta novel betacoronavirus , human coronavirus ( hcov - emc ) , has recently been detected in humans with severe respiratory disease .
further characterization of hcov - emc suggests that this virus is different from severe acute respiratory syndrome coronavirus ( sars - cov ) because it is able to replicate in ... |
today , endobronchial ultrasound ( ebus ) has emerged as a routinely performed procedure in diagnostic bronchoscopy .
first , endosonography was used in the field of gastrointestinal endoscopy . particularly for staging tumors of the esophagus and cardia,1 endosonography
several studies have showed that endoscopic ... | endobronchial ultrasound ( ebus ) has emerged as a routinely performed procedure in diagnostic bronchoscopy .
extending the view beyond the airway wall , ebus provides evaluation of tumor involvement of tracheobronchial wall and mediastinum and plays an essential role as a guidance technique for peripheral pulmonary ... |
chronic subdural hematoma ( csdh ) is a relatively common disease encountered in neurosurgical practice , occurring at a rate of 1 - 2 per 100,000/year . with advanced imaging technologies , such as computed tomography ( ct ) and magnetic resonance image ( mri ) ,
many studies have been conducted to understand the pa... | objectivebrain atrophy and subdural hygroma were well known factors that enlarge the subdural space , which induced formation of chronic subdural hematoma ( csdh ) .
thus , we identified the subdural volume that could be used to predict the rate of future csdh after head trauma using a computed tomography ( ct ) volu... |
simultaneous presence of esophageal varices ( ev ) and achalasia is an uncommon clinical scenario .
previous reports suggest placement of a transjugular intrahepatic portosystemic shunt ( tips ) and surgical myotomy or endoscopy therapy for treatment 1 . for patients who are
not candidates for a tips , injection of... | background and study aims : previous reports of simultaneous presence of esophageal varices ( ev ) and achalasia suggest placement of a transjugular intrahepatic portosystemic shunt ( tips ) and surgical myotomy or endoscopic therapy .
we report the case of a 64-year - old man who received anticoagulant therapy for a... |
mycorrhizal fungi help host plants absorb minerals ( especially phosphate ) and water and enable plants to develop resistance against stressors such as drought and heavy - metal contamination of soils .
ectomycorrhizal ( ecm ) fungi have a relationship with the roots of forest woody plants and play important roles in... | in this study , the effect of soil ameliorators on ectomycorrhizal ( ecm ) fungal communities in coal mine spoils was investigated . organic fertilizers and slaked lime were applied as soil ameliorators in 3 abandoned coal mine spoils .
one year after the initial treatment , roots of pinus densiflora seedlings were c... |
the study protocol was approved by the institutional review board of severance cardiovascular hospital , yonsei university health system , and adhered to the declaration of helsinki .
all 2136 subjects ( 1068 with af patients and 1068 with age- and sex - matched control subjects ) provided written informed consent . ... | backgroundgenomewide association studies have identified several loci associated with atrial fibrillation ( af ) and have been reportedly associated with response to catheter ablation for af in patients of european ancestry ; however , associations between top susceptibility loci and af recurrence after ablation have n... |
1a ) . the outer nuclear membrane ( onm ) is contiguous with the endoplasmic reticulum ( er ) and shares a number of integral membrane components .
, the inner nuclear membrane ( inm ) contains a distinct set of proteins and lipids from either the onm or the er . proteomic analysis of the inm indicates that it is com... | the defining feature of eukaryotic cells is the double lipid bilayer of the nuclear envelope ( ne ) that serves as a physical barrier separating the genome from the cytosol .
nuclear pore complexes ( npcs ) are embedded in the ne to facilitate transport of proteins and other macromolecules into and out of the nucleus... |
in recent decades , significant progress has been made in the application of information technologies and communication technologies in the search and recovery of information resources .
one of the areas that has dramatically changed after the introduction of information technology is medical education .
it aims to... | introductionthe significance and validity of web - based scientific databases are increasing dramatically in the scientific community .
moreover , a great number of students use these resources without having sufficient and accurate knowledge and understanding . in order for students to use these databases and electr... |
plasmodium falciparum , an
intraerythrocytic parasite that causes the most severe form of human malaria ,
is endemic to haiti where it caused 32 739 infections and contributed to an
estimated 741 malaria deaths in 2006 [ 13 ] .
malaria infection poses a risk to
the 140 000 travelers from nonendemic cou... | malaria is one of the most common causes of febrile illness in travelers .
coinfections with bacterial , viral , and fungal pathogens may not be suspected unless a patient fails to respond to malaria treatment . using novel immunohistochemical and molecular techniques , plasmodium falciparum , clostridium perfringens... |
the author said that the facial appearance at birth resemble darhinencephaly and inaddition showed frontal sinus hypoplasia and nasal mucosal atrophy .
there has been a great deal of debate regarding the extent of deformity in patients with this syndrome .
some believe , it involves only the nasal region whereas ot... | binder 's syndrome is an uncommon entity characterized by midfacial hypoplasia along with class iii incisal relationship .
the individuals with this syndrome are easily recognizable and the syndrome is mostly associated with other malocclusions .
the current article presents two cases of this rare syndrome and desc... |
a 61-year - old woman with a left ovarian cyst was scheduled for laparoscopic ovarian cystectomy under general anesthesia . at age 49
a transthoracic echocardiogram ( tte ) revealed decreased lv cavity size and mild to moderate lv systolic dysfunction with an ejection fraction ( ef ) of 40% by visual estimation .
t... | isolated left ventricular noncompaction ( lvnc ) is a rare primary genetic cardiomyopathy characterized by prominent trabeculation of the left ventricular wall and intertrabecular recesses .
perioperative management of the patient with lvnc might be challenging due to the clinical symptoms of heart failure , systemic... |
vital parameters are monitored and intubation provides a safe airway ; drugs ensure analgesia and suppress vegetative reactions .
however , the use of general anesthesia precludes intraoperative monitoring of higher brain functions , and lesions made to the central nervous system being detected when reversibility of ... | background . surgical stress triggers an inflammatory response and releases mediators into human plasma such as interleukins ( ils ) .
awake craniotomy and craniotomy performed under general anesthesia may be associated with different levels of stress .
our aim was to investigate whether those procedures cause diff... |
the intensive care units are treatment units that provide the vital support to the critically ill patients .
nosocomial infections ( nis ) are one of the most serious complications in intensive care unit ( icu ) patients because they lead to high morbidity , mortality , length of stay and cost .
although only 510% ... | summarybackgroundnosocomial infections are one of the most serious complications in intensive care unit patients because they lead to high morbidity , mortality , length of stay and cost .
the aim of this study was to determine the nosocomial infections , risk factors , pathogens and the antimicrobial susceptibilitie... |
sirtuins are a highly conserved family of proteins found in all organisms from yeast to mammals . all are orthologues of the yeast protein ,
silent information regulator 2 ( sir2 ) and their primary targets are acetylated lysines of various peptides and proteins , including histones . along with sequence homology
... | the sirtuins are a family of orthologues of yeast sir2 found in a wide range of organisms from bacteria to man .
they display a high degree of conservation between species , in both sequence and function , indicative of their key biochemical roles .
sirtuins are heavily implicated in cell cycle , cell division , tr... |
pars planitis is a subset of intermediate uveitis characterized by the formation of snowbank or snowball in the absence of an associated infection or systemic disease . in patients with pars planitis
, the spectrum varies between asymptomatic patients at one end and the presence of progressive inflammation that leads... | purpose . to evaluate the surgical outcome of scleral buckling ( sb ) in rhegmatogenous retinal detachment ( rrd ) patients associated with pars planitis
. methods .
retrospective review of rrd patients ( 32 eyes of pars planitis rrd and 180 eyes of primary rrd ) who underwent sb .
we compared primary and final a... |
ochratoxin a ( ota ) is a mycotoxin produced by several food - borne species of aspergillus and penicillium fungi .
ota occurs in various food materials and therefore humans are continuously exposed to relatively small amounts of it . because of its wide occurrence and consequent exposure , together with a potent car... | the in vitro and in vivo evidence compatible with a role for oxidative stress in ota carcinogenicity has been collected and described .
several potential oxido - reduction mechanisms have been identified in the past .
more recently , the possibility of a reduction of cellular antioxidant defense has been raised as ... |
acquired perforating collagenosis ( apc ) is known to be a really difficult disease to treat .
this fact complicates the development of an effective therapy . to date , several treatments have been used , including corticosteroids , retinoids , antihistamines , antibiotics , allopurinol and phototherapy , with variab... | acquired perforating collagenosis ( apc ) is a rare perforating dermatosis characterized by transepidermal collagen elimination .
we describe a 65-year - old patient , with long - standing type 2 diabetes mellitus and a 2-year history of itchy hyperkeratotic nodules situated on the back , who was subsequently diagnos... |
research publications are effectively the currency of scientific work . they represent the public cumulative record of science , documenting empirical results and providing a forum for theorizing , debate , and the gradual advance of scientific knowledge .
although publications are not the end point of scientific res... | introductiona pilot study by 6 clinical and translational science awards ( ctsas ) explored how bibliometrics can be used to assess research influence.methodsevaluators from 6 institutions shared data on publications ( 4202 total ) they supported , and conducted a combined analysis with state - of - the - art tools .
... |
rheumatoid arthritis ( ra ) is a chronic systemic autoimmune inflammatory disease that is characterized by synovial inflammation and cartilage and bone destruction .
interleukin- ( il- ) 6 is implicated in ra pathogenesis [ 2 , 3 ] . after binding to the il-6 receptor ( il-6r )
, il-6 mediates a systemic inflammato... | t helper 17-related cytokines have been implicated in rheumatoid arthritis ( ra ) pathogenesis .
the study aimed to identify cytokines associated with the treatment response of ra patients to tocilizumab ( tcz ) , a humanized monoclonal antibody against the interleukin- ( il- ) 6 receptor . as an independent substudy... |
nationwide mammography screening ( nms ) is the most
successful method for the early detection of breast cancer . there
exist differing opinions concerning the details of an ideal nms programme , with a body of opinion arguing that it should involve women over the age of
40 attending an annual mammography examina... | in nationwide mammography screening , thousands of mammography examinations must be processed .
each consists of two standard views of each breast , and each mammogram must be visually examined by an experienced radiologist to assess it for any anomalies .
the ability to detect an anomaly in mammographic texture is... |
we trapped mammals at 7 sites along a forest - to - urban gradient in maryland and washington , dc , usa , from early june to late september 2005 and in april 2006 .
the sites included 1 forested area ( smithsonian environmental research center , edgewater , md ) , 2 large wooded parks ( rock creek park , rockville ,... | we examined west nile virus ( wnv ) seroprevalence in wild mammals along a forest - to - urban gradient in the us mid - atlantic region .
wnv antibody prevalence increased with age , urbanization , and date of capture for juveniles and varied significantly between species .
these findings suggest several requiremen... |
known human influenza dates back to the 12th century , but most lessons about its epidemiology have been learned from the three welldocumented pandemics of the 20th century that occurred during 19181919 , 19571958 , and 19681969 .
influenza pandemics occur when a novel influenza virus emerges because of an antigenic ... | please cite this paper as : mohamed et al .
( 2011 ) communicability of h1n1 and seasonal influenza among household contacts of cases in large families .
influenza and other respiratory viruses 6(3 ) , e25e29 .
background quantitative knowledge of the transmissibility of influenza is crucial to its prevention ... |
sweet s syndrome is an acute febrile neutrophilic dermatosis typically characterized by the sudden onset of pyrexia , increased number or percent of neutrophils , and painful red skin lesions that consist of a diffuse dermal infiltrate of neutrophils ; in addition , the symptoms and lesions promptly respond to systemic... | background : sweet s syndrome , also referred to as acute febrile neutrophilic dermatosis , can either occur as an idiopathic disorder or associated with another condition , including cancer , or induced by exposure to a drug .
proton pump inhibitors selectively inhibit gastric parietal cell h+-k+-adenosine triphosph... |
lung cancer is the leading cause of cancer death in both men and women and one of the leading causes of death worldwide .
non small cell lung cancer ( nsclc ) represents ~80% of all types of lung cancer .
most patients present with locally advanced ( stage iii ) or metastatic ( stage iv ) cancer [ 2 , 3 ] . despite... | standard treatments for nonsmall cell lung cancer ( nsclc ) , such as surgery , chemotherapy , and radiotherapy , often lead to disappointing results . unfortunately
, also the various immunotherapeutic approaches so far tested have not produced satisfactory results to be widely applied in the clinical practice .
h... |
in accordance with the who definition of health and its conceptualization of health and disability ( international classification of functioning , disease , and health ) [ 1 , 2 ] , this article examines the alarming discord between the epidemiology of hypertension , type 2 diabetes mellitus , and obesity and the low p... | in accordance with the who definition of health , this article examines the alarming discord between the epidemiology of hypertension , type 2 diabetes mellitus ( t2 dm ) , and obesity and the low profile of noninvasive ( nondrug ) compared with invasive ( drug ) interventions with respect to their prevention , reversa... |
osteonecrosis of the hip , previously named avascular necrosis , is a naturally progressive disease typically affecting young individuals ( the mean age approximately 35 years old ) ( 1 ) .
it occurs when blood supply to the femoral head is disrupted , resulting in infarction and avascular necrosis of bone .
severa... | purpose of the study : osteonecrosis of the hip mostly affects young individuals and often progresses to a debilitating disease .
several treatment modalities exist , but none are completely satisfactory .
this study evaluates the clinical outcome of patients treated with core decompression and insertion of a porou... |
changes in body composition can very often cause chronic diseases , and as a result have become a primary concern.1 lean body mass ( lbm ) and fat mass ( fm ) are body composition states that change continuously and are closely related to the aging process when compared with other factors.2,3 moreover , a strong link h... | backgroundthe purpose of this study was to examine the differences in anthropometric measurements using an aerobic and pilates exercise program which lasted 24 weeks.methodthis was a clinical intervention study of 303 women over the age of 60 living in novi sad , serbia .
changes in body mass index and skinfold thick... |
the concept of tactile agnosia refers to patients who are unable to recognize objects in one modality in the presence of relatively intact sensory functions and adequate cognition . compared with visual agnosia , relatively few reports of tactile agnosia
have been described in the literature . in 1895 , wernicke re... | a 54-year - old female showed amorphagnosia without ahylognosia and tactile agnosia 40 days after the onset of right cerebral infarction .
her basic somatosensory functions were normal .
the appreciation of substance qualities ( hylognosia ) was preserved , but the patient 's inability to recognize the size and sha... |
dental plaque is a film of microorganisms on the tooth surface that plays an important role in the development of caries and periodontal diseases [ 13 ] .
corrective treatment for such infectious diseases requires the reduction and/or elimination of bacterial accumulations in the retentive sites on the top of the tee... | silibinin is a composition of the silymarin group as a hepatoprotective agent , and it exhibits various biological activities , including antibacterial activity . in this study , the antibacterial activities of silibinin were investigated in combination with two antimicrobial agents against oral bacteria .
silibinin ... |
many , if not all , cellular processes are driven by multiprotein complexes . in the nucleus , control of gene expression is achieved through assembly of such molecular machines on genomic loci in a highly controlled manner .
these complexes contain combinations of regulators such as transcription factors ( tfs ) , c... | summarycell fate is governed by combinatorial actions of transcriptional regulators assembling into multiprotein complexes .
however , the molecular details of how these complexes form are poorly understood .
one such complex , which contains the basic - helix - loop - helix heterodimer scl : e47 and bridging prote... |
twenty - four sd rat ( 6 to 8 weeks old , 150 to 200 g ) were procured from orient bio ( seongnam , korea ) and were accommodated under specific pathogen - free conditions .
all trials were performed in compliance with the association for research in vision and ophthalmology statement for the use of animals in ophtha... | purposeischemia - reperfusion injury ( i / r injury ) is known not only to induce hypoxic and oxidative stress , but also to cause retinal degeneration in rats .
crystallins , known to inhibit the formation of reactive oxygen species , reduce apoptotic cell death . our goal was to clarify not only the role of i / r i... |
multiple sclerosis ( ms ) is a chronic autoimmune demyelinating disease affecting the central nervous system .
postural imbalance is often described as one of the initial symptoms of ms [ 25 ] .
it is one of the most disabling ms symptoms that affects about 75% of patients during the course of the disease [ 6 , 7 ]... | purpose .
the aim of the study was to investigate differences in balance control between individuals with multiple sclerosis ( ms ) and healthy control subjects using clinical scales and instrumented measures of balance and determine relationships between balance measures , fatigue , and disability levels in individu... |
although conception is discouraged in woman with eisenmenger 's syndrome , as maternal mortality is 30%-50% ; but in inevitable circumstances , meticulous planning of anesthesia can help the parturient survive the ordeal of a cesarean section .
a 27-year - old pregnant female , 50 kg ( gravida three para one ) was ad... | we describe a case of a pregnant patient with a large ventricular septal defect ( vsd ) and pulmonary artery hypertension , presented to the hospital and underwent elective cesarean section under epidural anesthesia and postoperative analgesia .
the procedure was uneventful till the patient was discharged on 10th day... |
the observation that g - rich dna can form a myriad of secondary structures was made in the 1960s , however , it was not until the late 1980s that three seminal papers described the in vitro formation of g - quadruplexes [ 13 ] .
certain g - rich sequences can fold into secondary structures composed of planar g - qua... | replication protein a ( rpa ) plays an essential role in dna replication by binding and unfolding non - canonical single - stranded dna ( ssdna ) structures . of the six rpa ssdna binding domains ( labeled a - f ) ,
rpa - cde selectively binds a g - quadruplex forming sequence ( 5-taggggaagggttggagtgggtt-3 called gq2... |
cataract is defined as an opacity of the lens or its capsule and is the most common cause of preventable blindness worldwide .
a variety of systemic drugs such as corticosteroids , amiodarone , and antipsychotics have been implicated in the causation of cataract .
ocular adverse effects in schizophrenic patients ar... | a variety of systemic drugs including corticosteroids , amiodarone and antipsychotics have been known to cause cataract formation .
typical antipsychotics such as chlorpromazine have been reported to cause cataract formation in varying rates ranging from 22% to 80% .
cataract as an adverse effect resulting from the... |
childhood obesity is associated with a host of negative health outcomes resulting in a major public health concern for americans .
it is well appreciated that environmental and behavioral factors contribute to childhood obesity with the immediate family having direct influences on its development .
considerable e... | objective . the aim was to investigate the influence of feeding styles and food parenting practices on low - income children 's weight status over time . method .
participants were 129 latina parents and their head start children participating in a longitudinal study .
children were assessed at baseline ( 4 to 5 ye... |
estradiol-17 ( e2 ) is essential for all aspects of reproductive function in females through activation of estrogen receptors ( ers ) . in the rat e2
the pituitary expresses both estrogen receptors , er and er , and it responds to both er specific and er specific agonists .
phytoestrogens are plant - based estrogen... | we examined the response of rat female pituitary at different metabolic stages to treatments with estrogenic compounds and vitamin d analogs .
immature or ovariectomized ( ovx ) female rats responded by increased creatine kinase specific activity ( ck ) to estradiol-17 ( e2 ) , genistein ( g ) , daidzein ( d ) , bioc... |
several
decades of research have shown that the altered transcriptional
activity of cancer cells renders them sensitive to small - molecule
inhibitors of chromatin regulatory proteins .
this work culminated
in the approval of the histone deacetylase inhibitor vorinostat for
the treatment of diffuse large b ... | chromatin modifying proteins are
attractive drug targets in oncology ,
given the fundamental reliance of cancer on altered transcriptional
activity .
multiple transcription factors can be impacted downstream
of primary target inhibition , thus making it challenging to understand
the driving mechanism of act... |
after age of 40 , the lifetime risk of developing cvd is 49% for men and 32% for women .
although advances in medical and surgical management of cvd have substantially reduced cardiac mortality rates in the united states ( us ) , individuals with cvd remain at increased risk for further cardiac events , including uns... | background . cardiovascular disease ( cvd ) is a major cause of increased morbidity and mortality globally .
clinical practice guidelines recommend that individuals with cvd are routinely instructed to engage in self - care including diet restrictions , medication adherence , and symptom monitoring
.
objectives .... |
the nucleotide sequence corresponding to nucleotides 1,1051,123 of mouse klf15 mrna ( nm_023184 ) was synthesized as complementary antiparallel oligomers with a loop sequence ( acgtgtgctgtccgt ) : 5-gtttgcggtaagatgtacatcaaacgtgtgctgtccgtttggtgtacatcttgctgcttttt-3 ( forward ) and 5-atgcaaaaagcagcaagatgtacaccaaacggacagca... | objectivean increase in the rate of gluconeogenesis is largely responsible for the hyperglycemia in individuals with type 2 diabetes , with the antidiabetes action of metformin being thought to be achieved at least in part through suppression of gluconeogenesis.research design and methodswe investigated whether the tra... |
rinm5f cells were cultured at 37 c in
humidified air containing 5% co2 in rpmi 1640 medium containing
l - glutamine ( 2 mm ) , fetal calf serum ( 10% ) , hepes ( 1
mm ) , and 2-mercaptoethanol ( 50 m ) . cells were
passaged every 34 days when confluent .
pancreatic
-cells were isolated from 3-week - ol... | ryanodine receptors ( ryr ) are ca2 + channels that mediate
ca2 + release from intracellular stores in response to diverse
intracellular signals . in rinm5f insulinoma cells , caffeine , and
4-chloro - m - cresol ( 4cmc ) , agonists of ryr ,
stimulated ca2 +
entry that was independent of store - operated ... |
serijska merenja natriuretskih peptida kod pacijenata sa akutnim koronarnim sindromom su pokazala da su njihove vrednosti u kasnijoj , hroninoj fazi bolji prediktor prognoze i pouzdaniji indikator funkcije leve komore nego one u akutnoj fazi . stoga
je cilj ovog rada da se ustanove vrednosti nt - probnp - a 6 meseci ... | summarybackgroundsince serial analyses of nt - probnp in patients with acute coronary syndromes have shown that levels measured during a chronic , later phase are a better predictor of prognosis and indicator of left ventricular function than the levels measured during an acute phase , we sought to assess the associati... |
climate change affects health through multiple pathways such as less clean air , less safe drinking water , availability of foods and extreme heat ( 1 ) . increasing global temperatures are expected to impact on yields of food crops and increase global food insecurity ( 2 ) , which could have a bigger impact on health(... | background / objectiveschool meals represent the largest sector in government food procurement in the uk .
this paper aims to quantify , simultaneously , the nutritional quality and carbon footprint of meals provided by primary schools in england.methodsthe school food trust conducted the primary school food survey ... |
cervical radiculopathy caused by a compressive lesion arising from degenerative spondylotic change tends to be surgically treated either by discectomy with or without interbody fusion via an anterior or posterior surgical approach .
the initial surgical management was a posterior laminectomy or a smaller keyhole fora... | objectiveanterior cervical microforaminotomy ( acmf ) is a motion - preserving surgical procedure .
the purpose of this study is to assess radiologic changes of operated and adjacent segments after acmf.methodswe retrospectively reviewed 52 patients who underwent acmf between 1998 and 2008 . from x - ray film - based... |
obsessive compulsive disorder was once thought to be rare , but recent data estimate it to be the fourth most common psychiatric disorder with a lifetime prevalence of 2% to 3% . as per dsm - iv - tr ,
patients with ocd exhibit varying degrees of insight into the validity of their beliefs , including patients with p... | obsessive compulsive disorder ( ocd ) is a common disorder , but some of its atypical presentations are uncommon and difficult to diagnose .
we report one such case which on initial presentation appeared to be psychotic protocol but after detailed workup was diagnosed as ocd with marked avoidance symptoms . |
thiobases are a class
of nucleobase analogues , molecules that are
structurally similar to the canonical nucleobases found in dna .
they
differ from the canonical nucleobases only by the substitution of
carbonyl oxygen atoms by sulfur atoms , and this chemical similarity
makes the thiobases important nucleo... | the
solvatochromic effects of six different solvents on the uv
absorption spectrum of 2-thiocytosine have been studied by a combination
of experimental and theoretical techniques .
the steady - state absorption
spectra show significant shifts of the absorption bands , where in
more polar solvents the first ... |
use of angiotensin receptor blockers ( arbs ) in the third trimester may cause renal failure in the neonate which may be irreversible if associated with renal tubular dysgenesis .
this case report highlights the importance of educating the practitioners about appropriate use of drugs in pregnancy .
a 7-day - old ma... | maternal use of drugs during pregnancy may cause irreversible renal failure in the newborn .
this report highlights the adverse effect of telmisartan during the last trimester of pregnancy .
the neonate presented with oliguric renal failure and the renal histology showed proximal tubular dysgenesis . |
diets rich in saturated dietary lipids are associated with increased white adipose tissue ( wat ) inflammation and metabolic disease ( kennedy et al . , 2009 ) , whereas diets rich in polyunsaturated fatty acids have been shown to counteract inflammation and promote a lean and metabolically healthy phenotype ( buckle... | summarydietary lipids may influence the abundance of circulating inflammatory microbial factors .
hence , inflammation in white adipose tissue ( wat ) induced by dietary lipids may be partly dependent on their interaction with the gut microbiota . here , we show that mice fed lard for 11 weeks have increased toll - ... |
major depressive disorder ( mdd ) is one of the most common and costly psychiatric disorders , which is characterized by pervasive feelings of sadness , anxiety , low self - esteem , and social behavior abnormalities . with this mental disorder ,
most of the mdd patients suffer more than one recurrence of depressive ... | background : most previous neuroimaging studies have focused on the structural and functional abnormalities of local brain regions in major depressive disorder ( mdd ) . moreover , the exactly topological organization of networks underlying mdd remains unclear .
this study examined the aberrant global and regional to... |
the primary form occurs in children and young adults . in the absence of other disorders , it commonly shows localized lesions of the face , head and neck that have a tendency to resolve within two months to two years .
there are no clinical criteria to distinguish primary cases from cases associated with mycosis fun... | follicular mucinosis is an uncommon inflammatory disorder that characteristically presents as follicular papules and/or indurated plaques .
the face , neck , and scalp are the most frequently affected sites , although lesions may occur on any site of the body .
histologically , the disorder is characterized by muci... |
overall the prognosis in patients with differentiated thyroid cancers ( dtc ) is good . with appropriate treatment , the majority of these patients
get cured except in patients with metastasis where the prognosis is worse [ 2 , 3 ] .
management of patients with differentiated thyroid cancer involves total thyroidec... | background . about 90% of thyroid cancers are differentiated thyroid cancers .
standard treatment is total thyroidectomy followed by radioactive i131remnant ablation and tsh suppression with thyroxine .
unsuccessful ablation drastically affects the prognosis of patients with dtc particularly high risk individuals ;... |
cervical dystonia , the most frequent adult focal dystonia , is a syndrome characterized by involuntary twisting movements of the head , leading ultimately to temporary or constant abnormal postures interfering with voluntary movement [ 1 , 2 ] . despite over a century of research since its first description in the lit... | traditionally , the pathophysiology of cervical dystonia has been regarded mainly in relation to neurochemical abnormities in the basal ganglia .
recently , however , substantial evidence has emerged for cerebellar involvement . while the absence of neurological cerebellar signs in most dystonia patients may be con... |
it has been well established that alcohol use or cigarette smoking or both are the most significant risk factors for the development of head and neck squamous cell carcinomas ( hnsccs ) .
however , nearly every head and neck oncologist has come across patients , most of them young , with little or no tobacco or alcoh... | human papillomavirus ( hpv ) is detected in a subset of patients with head and neck squamous cell carcinoma , most frequently in tumors in the waldeyer 's ring ( palatine tonsil and base of tongue ) .
several studies suggest that patients with hpv - positive tumors have better survival with either concurrent chemorad... |
valvular heart diseases ( vhd ) surround a number of common cardiovascular disorders that account for 15% of all cardiac surgical procedures in the world .
one of the most important pathogeneses of coronary artery stenosis and vhd is inflammatory response of immune system .
prevalence and incidence of cardiovascula... | background and objectives .
valvular heart diseases are among the frequent causes of cardiac surgery .
some patients have a well - known rheumatic condition .
heart valves are fragile connective tissues which are vulnerable to any systemic autoimmune diseases .
this study was designed to evaluate the frequency ... |
a variety of implant systems have been developed and adopted over time , and several systems have been improved by the addition of distinctive features . each system has its own advantages and disadvantages .
proper design , material , surface treatment , surgical method , host site and leading conditions1,2 have all... | purposethe purpose of this study was to compare removal torques and surface topography between laser treated and sandblasted , large - grit , acid - etched ( sla ) treated implants.materials and methodslaser - treated implants ( experimental group ) and sla - treated implants ( control group ) 8 mm in length and 3.4 mm... |
this cross - sectional study included 49 patients with graves ' ophthalmopathy who were followed at the department of ophthalmology , yonsei university college of medicine between july 2008 and december 2008 ( referred to as the graves ' group ) .
we excluded patients who were not biochemically euthyroid to eliminate... | purposeto assess quality of life and depressive status in korean patients with graves ' ophthalmopathy.methodsa cross - sectional study of 49 patients ( mean age , 41 years ; sex ratio , m : f=11:38 ) with graves ' ophthalmopathy ( referred to as the graves ' group ) and 48 age - matched and sex - matched controls ( me... |
a descriptive cross - sectional survey of the entire dental and medical undergraduate students from two colleges of raichur was carried out .
this well - structured , questionnaire elicited information on demographic characteristics , hiv / aids knowledge , source of information , interpersonal communication concerni... | background and objectives : human immunodeficiency virus ( hiv ) is a major public health challenge .
unjustified calls for the isolation of patients with hiv infection might further constrain the potential for expansion of clinical services to deal with a greater number of such patients .
this infectious illness c... |
when gels and emulsions are used in a combined form the dosage forms are referred to as emulgels [ 1 , 2 ] . as the name suggests they are the combination of emulsion / microemulsion and gel . in recent years
, there has been great interest in the use of novel polymers with complex functions as emulsifiers and thicke... | the purpose of the present study was to develop and optimize the emulgel system for mtz ( metronidazole ) , a poorly water soluble drug .
the pseudoternary phase diagrams were developed for various microemulsion formulations composed of capmul 908 p , acconon mc8 - 2 , and propylene glycol .
the emulgel was optimiz... |
novel spectral - domain optical coherence tomography ( sd - oct ) findings in posterior microphthalmos ( pm ) include cystoid changes in the papillomacular fold ( pmf ) .
these changes may be misdiagnosed as cystoid macular edema ( cme ) and may trigger unnecessary treatment including intravitreal injections .
we r... | purposenovel spectral - domain optical coherence tomography ( sd - oct ) findings in posterior microphthalmos ( pm ) include cystoid changes in the papillomacular fold ( pmf ) .
these changes may be misdiagnosed as cystoid macular edema ( cme ) and may trigger unnecessary treatment including intravitreal injections .... |
autosomal dominant polycystic kidney disease ( adpkd ) is characterized by progressive cyst formation in the kidneys leading to massive kidney enlargement . over time
renal cysts may rupture leading to hematuria and pain . a pyogenic infection may also be located in these cysts .
adpkd patients with chronic pain re... | autosomal dominant polycystic kidney disease ( adpkd ) is the most common hereditary kidney disease .
it is characterized by progressive cyst formation in both kidneys , often leading to end - stage kidney disease .
indications for surgical removal of an adpkd kidney include intractable pain , hematuria , infection... |
chronic pain is among the many conditions that have recently been associated with vitamin d deficiency .
a number of studies have suggested a link between low levels of vitamin d and higher incidence of chronic pain [ 24 ] .
furthermore , indirect evidence that vitamin d levels are important in pain is provided by ... | vitamin d deficiency
has been implicated in chronic pain .
immigrant
and ethnic minority populations have been shown
to have lower vitamin d levels than native
western populations and often to be vitamin d
deficient . ... |
monoamniotic twinning is a rare complication , occurring in less than 1% of monozygosity and is associated with a significant mortality rate [ 1 , 2 ] .
the most common cause of perinatal mortality in monoamniotic twins has been reported to be cord entanglement [ 1 , 2 ] .
cord entanglement has been reported in up ... | we retrospectively evaluated a series of 18 monoamniotic and 7 pseudomonoamniotic ( secondary to rupture in the membrane dividing monochorionic diamniotic twins ) twin gestations managed after 20 weeks ' gestation .
there were no significant differences in the incidence of neonatal death or umbilical cord entanglemen... |
diabetes is the most prevalent metabolic disease with a growing spread rate in word wide .
diabetes comes along with diverse disorders in glucose protein and lipid metabolism , and chronic blood sugar increase results in different organisms breakdown , malfunction , and insufficiencies .
diabetes is the cause of a... | background : diabetes is the most prevalent metabolic disease with a growing spread rate in word wide . short message service ( sms ) is of the most common public communication networks , which have brought about a broad spectrum of applications like social , cultural and service products in the late decade .
the obj... |
a 46-year - old male patient complained of severe ankle and foot pain , although he had undergone right above - the - knee ( ak ) amputation surgery due to severe infection three years earlier .
the patient 's initial visual analogue scale ( vas ) score in the pain clinic was 9/10 ( 0 is no pain , 10 is the most seve... | phantom limb pain is a phenomenon in which patients experience pain in a part of the body that no longer exists . in several treatment modalities ,
spinal cord stimulation ( scs ) has been introduced for the management of intractable post - amputation pain .
a 46-year - old male patient complained of severe ankle a... |
the niti archwires are widely employed in orthodontics because they present shape memory
effect and superelasticity combined to good mechanical properties .
the shape memory resulting from the pseudoelastic effect ( superelasticity ) and
thermoelastic effect is the main characteristic of these archwires and is cl... | objectives the shape memory resulting from the superelasticity and thermoelastic effect is
the main characteristic of thermally activated niti archwires and is closely
related to the transition temperature range ( ttr ) .
the aim of this study was to
evaluate the ttr of thermally activated niti archwires commer... |
information processing within the brain critically depends on rhythmic oscillatory activity that synchronizes neuronal networks .
synchronization leads to local and global coupling of network elements and times neuronal firing . by these means
, it enables the precise selection of relevant information . depending o... | spindle oscillations have been described during early brain development and in the adult brain . besides similarities in temporal patterns and involved
brain areas , neonatal spindle bursts ( nsbs ) and adult sleep spindles ( asss ) show differences in their occurrence , spatial distribution , and underlying mechanis... |
a 42-year - old costa rican female previously diagnosed with left eye autoimmune panuveitis presented with redness , pain and decreased vision to the bascom palmer eye institute ( bpei ) . after failing to respond to a course of oral prednisolone therapy , the patient received ivta in the left eye in costa rica , 2 mon... | we report two cases of fulminant toxoplasmic retinochoroiditis following intravitreal triamcinolone acetonide ( ivta ) administration .
case 1 : a 42-year - old female received ivta for presumed non - infectious panuveitis . within 2 months , she developed diffuse macular retinochoroiditis with optic disc edema . upo... |
proteus sp . is a gram - negative , facultatively anaerobic , rod - shaped bacterium .
its main pathological role is in infections of the urinary tract , but it can also cause wound infections and septicemia . it is widely distributed in soil and water .
genomic dna was extracted from pure culture of bacterial s... | we report draft genome sequence of proteus sp .
strain sas71 , isolated from water spring in aljouf region , saudi arabia .
the draft genome size is 3,037,704 bp with a g + c content of 39.3% and contains 6 rrna sequence ( single copies of 5s , 16s & 23s rrna ) .
the genome sequence can be accessed at ddbj / e... |
one of the often seen consequences of the aging process is the development of senile cataract , a disease that affects one of our most precious gifts , that of sight .
this so - called senile cataract usually occurs in those over 45 years of age .
approximately 75 percent of population over 75 suffer from lens opac... | many factors such as aging , changes in blood electrolytes levels , and possibly family history are involved in senile cataract formation .
changes in serum electrolytes levels can induce changes in aqueous electrolytes levels and effect on lens metabolism and probably cataract formation . in this paper , we study se... |
one of the main concerns regarding fissure sealants is weakening of the bond of this material that may lead to secondary caries .
as fissure sealants consist of a resin matrix , polymerization shrinkage may lead to weakening of the bond , resulting in microleakage that increases with time and leads to secondary bacte... | objective : the aim of this study was to investigate the mechanical properties ( flexural strength , micro - shear bond strength ) and remineralizing potential of fissure sealants by adding various concentrations of -tricalcium phosphate nanoparticles.materials and methods : this in - vitro study consisted of five expe... |
fine needle aspiration cytology ( fnac ) of enlarged lymph nodes is a useful screening test .
studies in the past have shown metastatic malignancy to be a major cause of enlargement of supraclavicular lymph nodes . in this study , we have attempted to analyze the pattern of presentation of supraclavicular lymphadenop... | aims : this study was taken up with the aim to investigate the pattern of supraclavicular lymphadenopathy among patients presenting to our tertiary care institution , evaluate the diagnostic efficacy of fine needle aspiration cytology ( fnac ) , and analyze the diagnostic pitfalls.materials and methods : a total of 215... |
patients ' quality of life ( qol ) and satisfaction assessment are becoming increasingly important in health care delivery [ 1 , 2 ] .
there is evidence that better qol and patient satisfaction might be associated with better medical outcome including reduced hospitalization and reduced mortality .
recently... | aim . to assess the degree of satisfaction among hemodialysis patients and the factors influencing this satisfaction
. methods .
patients were recruited from 3 saudi dialysis centers .
demographic data was collected . using 1 to 10 likert scale ,
the patients were asked to rate the overall satisfaction with ... |
rapid progression , familial aggregation , non - contributory medical history , rarity , severity and early age of onset of clinical manifestations are among the main characteristics of aggressive periodontitis .
this destructive periodontal disease results in severe bone loss , tooth loosening and eventual tooth los... | objectives : the aim of this study was to determine the cementum thickness in the first molars of patients with localized aggressive periodontitis ( lap ) compared to healthy individuals.materials and methods : this case - control study compared eight first molar teeth affected by lap with eight third molar teeth of he... |
endobronchial ultrasound - guided transbronchial needle aspiration ( ebus - tbna ) is a minimally invasive and safe technique that enables accurate diagnosis in various mediastinal lesions ( masses / lymph nodes ) .
indications of ebus - tbna have gradually expanded with use being reported for other indications such ... | endobronchial ultrasound - guided transbronchial needle aspiration ( ebus - tbna ) is a minimally invasive and safe technique for a sampling of mediastinal lesions .
indications for ebus - tbna have gradually expanded since its introduction .
the usual approach to cytological sampling of the thyroid gland is percut... |
a forty - nine - year - old woman was admitted to our orthopedic department for pain in the left knee that had lasted for two weeks .
the patient 's medical history revealed that she had been admitted to another hospital for pain in the right shoulder five months ago . during admission to another hospital
arthrosco... | we present a case of adult onset still 's disease ( aosd ) that was misdiagnosed as septic arthritis of the shoulder and knee .
a forty - nine - year - old woman was admitted for pain in the left knee .
the patient 's medical history showed that she had undergone arthroscopic irrigation twice and an open debridemen... |
abundant graft materials are used nowadays for the purpose of reducing the signs and symptoms of postoperative phase after surgical extraction and promote soft tissue healing and bone regeneration . among the several materials used to repair bone defects , autologous graft
however , the use of platelet - rich plasma ... | aim : the purpose of this study was to compare the efficacy of platelet - rich plasma ( prp ) , platelet - rich fibrin ( prf ) , and hydroxyapatite ( ha ) for reduction of pain and swelling , absence of dry socket , soft tissue healing , and bone regeneration after mandibular third molar extraction in human patients.ma... |
copd is characterized by a progressive decline in lung function and mental and physical comorbidities ( eg , depression , dystrophy , and heart failure).1 an exacerbation of copd is an acute event caused by several factors . to those patients who need ventilator support because of lung infection
the clinician s conce... | copd is characterized by a progressive decline in lung function and mental and physical comorbidities . it is a significant burden worldwide due to its growing prevalence , comorbidities , and mortality .
complication by bronchial - pulmonary infection causes 50%90% of acute exacerbations of copd ( aecopd ) , which m... |
pruritus , or itch , is defined as a displeasing feeling that irritates the desire to scrape .
certain systemic diseases known to cause pruritus include renal , cholestatic , hematologic , endocrine , and malignancy disorders .
uremic pruritus ( up ) is a common and upsetting problem of chronic kidney disease speci... | background .
although uremic pruritus is a common and upsetting problem of chronic kidney disease , there is no approved treatment for it .
this study was undertaken to find the efficiency of sertraline as a possible treatment for uremic pruritus .
methods .
19 esrd patients under hemodialysis with severe chron... |
the bond quality of the restorative material to the tooth substance is one of the factors that determine the longevity and clinical performance of dental restorations .
weakly bonded tooth - restoration interfaces are more prone to the effects of the masticatory forces and oral thermal stress in the short and long te... | objectivesthe objective of this in vitro study was to evaluate the marginal sealing ability of an ormocer in comparison with a hybrid composite when using thermocycling and load cycling procedures together in the study design.methodsmodified proximal class ii cavities were prepared on the mesial and distal surfaces of ... |
in conventional management of grave disease ( gd ) , there are three major options : antithyroid drugs , radioactive iodine ( rai ) therapy , and thyroidectomy ( 1 ) .
according to the guidelines of the american thyroid association and the american association of clinical endocrinologists , any one of these modali... | therapeutic plasma exchange ( tpe ) is one possible treatment for patients resistant to conventional antithyroid drugs or requiring urgent attention for thyrotoxicosis .
we report a 35-yr - old man with thyrotoxicosis , ultimately attributed to graves ' disease in whom antithyroid drug used initially was soon discont... |
chronic venous disease ( cvd ) is one of the most prevalent medical problems in the adult population of western european countries and usa with a significant impact on afflicted patients and on the healthcare system .
dysfunction of any of the normal structures of the venous system may lead to venous hypertension and... | the expression of proinflammatory cytokines / chemokines has been reported in in vitro / ex vivo settings of chronic venous insufficiency ( cvi ) , but the identification of circulating mediators that might be associated with altered hemodynamic forces or might represent innovative biomarkers is still missing . in this... |
the pulmonary vein ( pv ) has been the main target for catheter ablation in patients with atrial fibrillation ( af ) ever since it was identified as the major trigger for af.1)2 ) different techniques that target the pv include direct trigger ablation,3 ) segmental ostial pv isolation4 - 6 ) and circumferential pv isol... | background and objectiveswe aimed to investigate whether a large - sized lasso catheter could increase the success rate of immediate complete pulmonary vein ( pv ) antral isolation and improve the outcome of catheter ablation in atrial fibrillation ( af ) patients.subjects and methodsthis study included 107 consecutive... |
since the genetics and cell biology of higher eukaryotes are extremely complex , scientists looking for a good model have turned to the use of yeast as a simpler system for the study of various pathologies including virus proliferation and assay new drugs against these pathogenic agents . the yeast saccharomyces cere... | despite being simple eukaryotic organisms , the yeasts saccharomyces cerevisiae and schizosaccharomyces pombe have been widely used as a model to study human pathologies and the replication of human , animal , and plant viruses , as well as the function of individual viral proteins .
the complete genome of s. cerevis... |
we report a case of periprosthetic fracture of a 57-year - old male patient with bmhr .
the patient , having previously had a left total hip replacement for osteoarthritis , subsequently underwent right hip bmhr for osteoarthritis ( fig .
the surgery was uneventful and notching had not been noted at the time of sur... | total hip arthroplasty in the young leads to difficult choices in implant selection . until recently bone conserving options
were not available for younger patients with deficient femoral head bone stock .
the novel birmingham mid - head resection ( bmhr ) device offers the option of bone conserving arthroplasty in... |
biological effects of electromagnetic millimeter waves were observed in many experiments on various biological objects , starting from the bacteria to the whole human body as well as model systems in general . it was repeatedly noted that the nature of the microwaves on biological objects is different from the conventi... | temperature sensitivity of the fluorescence intensity of the organic dyes solutions was used for noncontact measurement of the electromagnetic millimeter wave absorption in water . by using two different dyes with opposite temperature effects , local temperature increase in the capillary that is placed inside a rectang... |
pituitary adenomas are common intracranial lesions ; autopsy and radiographic studies find a prevalence of 17%.1 prolactinomas are the most common form of endocrinologically active pituitary adenoma ; they account for 45% of pituitary adenomas encountered in clinical practice.2 prolactinomas are most often microadeno... | prolactinomas are the most common form of endocrinologically active pituitary adenoma ; they account for 45% of pituitary adenomas encountered in clinical practice .
giant adenomas are those > 4 cm in diameter
. less than 0.5% of pituitary adenomas encountered in neurosurgical practice are giant prolactinomas . ... |
a 48-year - old man presented with right knee pain that had been ongoing for 10 years prior and had not been the result of trauma ; he presented with difficulty in full extension or squatting .
the patient had received conservative treatment that included medication with non - steroidal anti - inflammatory drugs from... | unlike meniscal tears and chondral defects , the mucoid degeneration of the anterior cruciate ligament ( acl ) is a rare cause of knee pain and there have been no case reports of mucoid degeneration of both the acl and the posterior cruciate ligament ( pcl ) . a 48-year - old - male patient presented with knee pain and... |
spinal deformity surgery has the potential for massive blood loss15,19 ) . especially during long level lumbar or thoracic instrumented fusion with or without osteotomy
, blood loss may be substantial and transfusion is required in most cases 11,12 ) .
extensive blood loss can lead to massive blood transfusions , p... | objectivespinal deformity surgery has the potential risk of massive blood loss . to reduce surgical bleeding ,
the use of tranexamic acid ( txa ) became popular in spinal surgery , recently .
the purpose of this study was to determine the effectiveness of intra - operative txa use to reduce surgical bleeding and tr... |
the sleeve gastrectomy ( sg ) is the first part of the duodenal switch operation and leaves a lesser curvature tube after excising the fundus and greater curvature portion of the stomach .
this surgery has become more and more popular as the first stage in the treatment of obesity [ 1 , 2 ] .
minimally invasive sur... | objective .
robot - assisted sleeve gastrectomy has the potential to treat patients with obesity and its comorbidities . to evaluate the learning curve for this procedure before undergoing roux en - y
gastric bypass is the objective of this paper .
materials and methods .
robot - assisted sleeve gastrectomy was... |
sca is a heterogeneous monogenic disease due to a single mutation a / t at the sixth codon of the -globin gene ( s ) .
the clinical complications arising from sickle cell disease include vasoo - cclusive crisis and its outcomes . as a result of chronic hemolysis , hyperbilirubinemia is often observed leading to the f... | aim . to determine the implication of the polymorphism , namely , a(ta)ntaa of ugt1a1 in lithogenesis for the first time in tunisia among sickle cell anemia ( sca ) children patients .
material and methods .
our study was performed in 2010 and it involved 76 subjects chosen as control group characterized with norma... |
struma ovarii ( so ) is a rare form of germ cell derived ovarian tumor , which is defined by the presence of thyroid tissue comprising more than 50% of the overall tumor volume .
the vast majority of the variants of so are benign ( 95% ) ; however , malignant tumors have been reported in a small percentage of cases .... | struma ovarii ( so ) is a rare form of ovarian tumor , which is defined by the presence of thyroid tissue comprising more than 50% of the overall tumor volume .
the vast majority of the variants of so are benign ; however , malignant tumors have been reported in a small percentage of cases .
an aggressive multimoda... |
cytokinins are classic plant hormones that orchestrate growth , development and the integrity of stem cell populations .
cytokinin receptors are eukaryotic sensor histidine kinases that are activated both by naturally occurring adenine - type cytokinins and by urea - based synthetic compounds .
crystal structures o... | |
our modern world is constantly facing with the challenges of the outbreak of infectious diseases , traffic accidents , food poisoning , war , terrorist attacks and many other natural or non - natural disasters such as earthquake , landslide and flood , etc . to minimize the damage and the suffering the disasters might ... | abstractbackgroundit is widely accepted in many parts of the world thatcommunity nurses are of vital importance in various phases of disaster response and management . in china , however , it is not clear whether the chinese community nurses are able to assume disaster - related duties due to the lack of a systematic a... |
the ultimate goal of surgery has always been providing the best and most effective procedure with the least amount of postoperative complications , and pain and the best possible aesthetic results .
the first reported elective cholecystectomy was carried out by langenbuch in 1882 and open cholecystectomy became the... | the current standard - of - care for treatment of cholecystectomy is the four port laparoscopic approach .
the development of single incision / laparoendoscopic single site surgery ( silc / less ) has now led to the development of new techniques for removal of the gallbladder .
the use of silc / less is now current... |
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