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ankylosing spondylitis ( as ) is a chronic inflammatory rheumatic disease that affects especially males in the second and third decades of life , with a prevalence of 0.50.9% .
the main clinical symptom is inflammatory back pain typically occurring at night and morning stiffness improving after exercise .
the pain ... | the objective of this study is to investigate the prevalence of andersson lesions ( al ) in ankylosing spondylitis ( as ) patients who will start anti - tumor necrosis factor ( tnf ) treatment .
radiographs and magnetic resonance imaging ( mri ) of the spine were performed before therapy with anti - tnf .
als were ... |
episiotomy is performed with a pudendal block during second stage of labor to expand the opening of the vagina which
improves maternal and neonatal outcomes.it is one of the most common medical procedures
performed on women in iran , which have been reported 88.3% at ommolbanin hospital of
mashhad , in 2006 .
a... | introduction : episiotomy is a surgical incision made in the
perineum to enlarge it . perineal pain is the most common complaint of mothers after
episiotomy .
chamomile extract has been proposed as a sedative in traditional medicine .
this study was conducted to assess the effect of chamomile cream on the pain ... |
baseline samples from two studies of depression and distress among adult type 2 diabetic patients were included .
study 1 , our primary sample , used baseline data from the distress and depression in diabetes study ( 3d study ) , a noninterventional , three - wave , 18-month study of the prevalence and persistence of... | objectiveto identify the pattern of relationships between the 17-item diabetes distress scale ( dds17 ) and diabetes variables to establish scale cut points for high distress among patients with type 2 diabetes.research design and methodsrecruited were 506 study 1 and 392 study 2 adults with type 2 diabetes from commun... |
this is a prospective cohort study of patients admitted to a specialized geriatric icu at the liuhuaqiao hospital in guangzhou , china .
founded in 1933 , it grew out of the general hospital of guangzhou military command .
since 2009 , it has been open to the general public , and named liuhuaqiao , meaning flowi... | background.in older adults admitted to intensive care units ( icus ) , frailty influences prognosis .
we examined the relationship between the frailty index ( fi ) based on deficit accumulation and early and late survival.methods.older patients ( 65 years ) admitted to a specialized geriatric icu at the liuhuaqiao ho... |
chronic renal failure is a progressive deterioration of renal function impairment which leads to interference with the metabolism of body water and electrolytes .
two - three percent of the current world 's population is suffering from chronic renal failure and every year the rate increases twice .
the standard rec... | background : hemodialysis patients usually experience high levels of psychological stress , anxiety , and depression . reducing these matters in patients provides more psychological resources to cope with their physical situation.aim:the present study aimed to explore the efficacy of benson 's relaxation technique for ... |
cholesterol , l - a - pa , stearylamine ( sa ) , lactoperoxidase , monensin , 2,5-diphenyl oxazole , 1,4-bis[2-(5-phenyl oxazole ) ] benzene , guar gum , penicillin - g ( potassium salt ) , streptomycin sulphate , 2.5% trypsin in hbss ( hank s balanced salt solution ) and hepes ( ( 4-(2-hydroxyethyl)-1-piperazineethane... | the monensin , known to enhance the cytotoxicity of ricin and ricin - based immunotoxins is a very hydrophobic molecule and this limits its administration in optimum doses under in vivo conditions . in order to realise its full potential ,
monensin was intercalated into various liposomal formulations and its ability ... |
systemic lupus erythematosus ( sle ) is an autoimmune , chronic inflammatory disorder affecting the connective tissue of multiple organ systems .
it occurs on the background of disturbances of environmental , hormonal , and genetic factors .
no single clinical , laboratory , neuropsychological , and imaging test ca... | neuropsychiatric manifestations in systemic lupus erythematosus ( sle ) are common ; however , psychosis per se is bit uncommon
. they may be cognitive deficit , lupus headache , psychoses , seizures , peripheral neuropathy , and cerebrovascular events .
psychiatric symptoms in sle can be functionally independent p... |
moreover , in chemical ionization mass spectrometry ( cims ) , humidity
is involved in the complex processes taking place at and after chemical
ionization . from a practical point of view , humidity in cims is relevant
for quantification .
several general concepts are understood , such
as the influence of pro... | we report on a previously unknown
reaction mechanism involving
water in the fragmentation reaction following chemical ionization .
this result stems from a study presented here on the humidity - dependent
and energy - dependent endoergic fragmentation of allyl methyl sulfide
( ams ) upon protonation in a prot... |
medical records were retrospectively reviewed for cats with nasal lymphoma treated with
radiation therapy at the rakuno gakuen university veterinary teaching hospital .
the 30 cats
included in this study were treated between april 2004 and december 2011 .
all cats had
biopsies taken under general anesthesia a... | nasal lymphoma is the most common nasal tumor in cats and is generally a solitary and
radiosensitive tumor .
we retrospectively evaluated the response to radiation and survival
time in relation to apoptosis and ki-67 indices in feline nasal lymphomas treated with
radiation therapy .
the apoptotic and ki-67 in... |
cytokines are an intriguing group of soluble protein mediators with a large number of described actions but short biological range . these molecules are produced by a variety of cells , including monocytes , macrophages , lymphocytes , and endothelial cells .
such proteins include the pro - inflammatory cytokines int... | pro- and anti - inflammatory cytokines are elevated after cardiac surgery . the control of the release of these major paracrine proteins is becoming clearer and they have been shown to be involved in the activation of the coagulation / fibrinolysis pathway , among other cascades .
the association of a predominance of... |
a 47-year - old man was admitted with the chief complaint of persistent high fever and transient loss of consciousness .
although his general condition improved after intravenous acyclovir administration , the patient presented with visual loss in both eyes 4 days after admission . visual acuity in his right eye w... | purposethe report of a case of bilateral acute retinal necrosis after herpetic meningitis.case reporta 47-year - old man was admitted with the chief complaint of persistent high fever and transient loss of consciousness . although his general condition improved after intravenous acyclovir administration , the patient p... |
sarcoidosis is a systemic disorder of unknown etiologycharacterized by widespread development of noncaseating epithelioid cell granulomas in more than one organ system .
a review of the literature suggests that the relationship between sarcoidosis and malignancy is controversial ; however , new onset sarcoidosis has ... | we report on a rare case of sarcoidosis that developed after chemotherapy for ovarian cancer , and mimicked a cancer metastasis .
a 52-year - old female diagnosed with stage iii ovarian cancer underwent curative surgery and postoperative chemotherapy .
four months later , her whole - body positron emission tomograp... |
starting in 2000 , pegylated interferon- ( peg - ifn ) has been the treatment of choice for chronic hepatitis c virus ( hcv ) infections .
, we report for the first time a patient who experienced a relapse of vogt - koyanagi - harada ( vkh ) disease during treatment with peg - ifn and ribavirin therapy for hcv infect... | a 60-year - old woman , who had been diagnosed with and treated for vogt - koyanagi - harada ( vkh ) disease 17 years before , was receiving pegylated interferon- ? and ribavirin therapy for chronic hepatitis c virus .
three weeks after the start of therapy , she complained of visual blurring , eye pain , and an incr... |
an enormous change has taken place in ocular health issues , however , there are various problems facing ophthalmic public health worldwide . in the previous years
, the world health organization and the international agency for the prevention of blindness in partnership launched the global initiative to eradicate av... | backgroundvisual sciences have been progressing quickly in recent decades through globalization phenomenon .
an enormous change has taken place in ocular health issues , however , there are various problems facing ophthalmic public health worldwide . in the previous years
, the world health organization and the int... |
the extracellular matrix ( ecm ) is an insoluble supra - structure comprised of a variety of matrix components including fibronectin , glycosaminoglycans , chrondronectin , osteonectin , collagens , laminin , proteoglycans , and growth factors [ 16 ] .
the ecm provides the scaffold for cell attachment which is necess... | cell adhesion to the extracellular matrix ( ecm ) is essential for cell migration , proliferation , and embryonic development .
cells can contact the ecm through a wide range of matrix contact structures such as focal adhesions , podosomes , and invadopodia .
although they are different in structural design and bas... |
in this study , we analyzed 12 species of aquatic heteroptera belonging to five families : belostomatidae ( belostoma anurum and belostoma micantulum ) , gelastocoridae ( gelastocoris angulatus and gelastocoris flavus flavus ) , gerridae ( rheumatobates crassifemur crassifemur ) , notonectidae ( buenoa amnigenus , buen... | the heteroptera have holocentric chromosomes with kinetic activity restricted to the end of chromosomes .
the first meiotic division is reductional for the autosomes and equational for the sexual .
only a few species of this suborder have been analyzed . in this study , we observed the morphologies of the testes of... |
a 6-year - old girl 102 cm tall and weighing 17 kg , with chronic intestinal pseudo - obstruction was scheduled for multivisceral organ transplantation .
four - years earlier , she visited a hospital for abdominal distention and was diagnosed with gastric volvulus and congenital megacolon , for which she underwent ga... | multivisceral organ transplantation involves the transplantation of three or more abdominal organs , including small bowel , duodenum , stomach , liver , pancreas , colon , and so on .
the large amounts of cold and acidic loading into systemic circulation from the graft during multivisceral organ transplantation may ... |
myofibroblasts were first described in healing skin wounds , where it was hypothesized that they were responsible for the phenomenon of wound contraction.1 since then , cells morphologically similar to myofibroblasts have been described in many tissues , predominantly in pathological states where their sustained presen... | ( myo)fibroblasts are key players for maintaining skin homeostasis and for orchestrating physiological tissue repair .
( myo)fibroblasts are embedded in a sophisticated extracellular matrix ( ecm ) that they secrete , and a complex and interactive dialogue exists between ( myo)fibroblasts and their microenvironment .... |
fibrosing colonopathy ( fc ) is a rare entity associated with cystic fibrosis ( cf ) . until now ,
case report on an adult with cf who developed persistent abdominal pain due to a non - passable stricture in the right transverse colon .
initially we treated the patient with prednisolone pulse therapy and additive a... | objectivefibrosing colonopathy ( fc ) is a rare entity associated with cystic fibrosis ( cf ) . until now ,
patients with stricturing fc have usually been treated surgically . in this instance , we aimed at avoiding surgery by applying a new conservative approach.methodscase report on an adult with cf who developed p... |
neuroferritinopathy is an autosomal dominant neurodegenerative disorder characterized by the deposition of iron and ferritin in the brain and a decreased level of serum ferritin .
seven different pathogenic mutations of the ferritin light chain gene have been identified [ 17 ] .
these mutations are predicted to aff... | neuroferritinopathy is a neurodegenerative disease which
demonstrates brain iron accumulation caused by the mutations in
the ferritin light chain gene . on brain mri in
neuroferritinopathy ,
iron deposits are observed as low - intensity
areas on t2wi and as signal loss on t2wi . on t2wi ,
hyperintense
abn... |
the mouse hypothalamic cell
line n29/4 was cultured as previously described
( 24 ) .
min6 cells ( obtained
with permission from jun - ichi miyazaki , osaka university ) were used between
passages 24 and 30 and grown in dulbecco 's modified eagle 's medium containing
25 mm glucose and supplemented with ... | leptin activates multiple signaling pathways in cells , including the
phosphatidylinositol 3-kinase pathway , indicating a degree of cross - talk with
insulin signaling . the exact mechanisms by which leptin alters this signaling
pathway and how it relates to functional outputs are unclear at present .
a
... |
alzheimer s
disease
( ad ) is a progressive neurodegeneration and a complex multifactorial
disorder among the elderly .
the pathological features of ad are the loss
of neurons in conjunction with the presence of oxidative stress , axonal
dystrophy , senile plaques , and neurofibrillary tangles . because of ... | alzheimer s
disease ( ad ) is one of the most complicated progressive neurodegeneration
diseases that involve many genes , proteins , and their complex interactions .
no effective medicines or treatments are available yet to stop or
reverse the progression of the disease due to its polygenic nature .
to facil... |
high blood pressure is estimated to affect more than one in three adults aged 25 and over , or about 1 billion people worldwide.1 this means that nearly 30% of our patients are suffering from hypertension .
various drugs are currently used to treat hypertension , but the effects of these drugs on other age - related ... | aimthe aim of this study was to evaluate the effects of calcium channel blocker ( ccb ) amlodipine ( aml ) , platelet rich plasma ( prp ) , and a mixture of both materials on bone healing.materials and methodsfifty - six male wistar rats were randomly divided into four groups : group a , tibia defect model with no trea... |
in a modern lifestyle people are chronically exposed to elevated amounts of lipids and nutrients , potentially leading to tissue dysfunction and disease . the adipose tissue is highly involved in the development of metabolic disorders such as cardiovascular disease ( cvd ) and type 2 diabetes mellitus ( t2 dm ) .
i... | adipose tissue metabolism is closely linked to insulin resistance , and differential fat distributions are associated with disorders like hypertension , diabetes , and cardiovascular disease .
adipose tissues vary in their impact on metabolic risk due to diverse gene expression profiles , leading to differences in li... |
ever since its origins in 1988 in the usa and france , laparoscopic cholecystectomy has fast become the gold standard for operative gall bladder removal .
studies have shown that laparoscopic cholecystectomy , as compared to the previous method of open cholecystectomy , has advantages in terms of lower mortality , le... | background : mini - laparoscopic cholecystectomy ( mlc ) has widened the horizons of modern laparoscopic surgery .
standard four port laparoscopic cholecystectomy ( slc ) , which has long been established as the gold standard for gall bladder diseases , is under reconsideration following the advent of further minim... |
afferent loop obstruction is a potentially life - threatening complication of billroth ii gastrectomy or roux - en - y hepaticojejunostomy ( ryhj ) .
afferent loop syndrome caused by an enterolith is rare.1 formation of the enterolith is presumed to be related to hypomotility or stasis of the bowel that is altered an... | afferent loop obstruction caused by enterolith formation is rare and can not be easily treated with endoscopy because of the difficulty associated with the nonsurgical removal of enteroliths .
a 74-year - old woman was admitted with fever and acute abdominal pain .
clinical features and imaging studies suggested af... |
sarcomas arising in abdomen and pelvis constitute 2530% of all soft tissue sarcomas ( sts ) , of which retroperitoneal sarcomas account for 15% , and intra - abdominal sarcomas account for 1015% ; < 5% of sarcomas appear as primary abdominal wall tumors .
the most commonly encountered histologic subtypes of retroperi... | background : data concerning treatment outcome and prognostic factors in sarcomas of abdomen and pelvis are sparse in literature .
methods and results : of 696 patients with nonrhabdomyosarcomatous soft tissue sarcoma registered at our center between june 2003 and december 2012 , 112 ( 16% ) patients of sarcomas aris... |
total daily energy expenditure is the sum of the thermic effect of feeding , the energy expended during physical activity , and resting energy expenditure ( ree ) .
ree represents the largest ( i.e. , 6075% ) component of total daily energy expenditure .
subsequently , increases in ree can influence daily energy ut... | increasing the rate of muscle protein synthesis is an energy consuming process that explains the acute elevations in resting energy expenditure ( ree ) observed 12 to 72 hours after a resistance exercise session .
we hypothesized that multiple sessions of resistance exercise combined with the intake of amino acids wo... |
srus manifests as rectal bleeding , mucoid discharge , straining , altered bowel habits , incontinence , tenesmus , rectal prolapse , and a sensation of incomplete defecation.1,2 the endoscopic findings of srus show variable patterns , including hyperemic mucosa , ulceration , and polypoid lesions.3 because of variable... | solitary rectal ulcer syndrome ( srus ) is an uncommon benign disease that is misdiagnosed as malignancy or inflammatory bowel disease because of similarities in clinical and endoscopic manifestations .
furthermore , srus with ulcerative colitis ( uc ) is extremely rare . to date , two cases have been reported in the... |
vascular dementia ( vad ) is the impairment of memory and cognitive functioning resulting from cerebrovascular disease ( cvd ) such as infarcts and leukoaraiosis .
although vad is considered to be the second most common cause of cognitive impairment after alzheimer 's disease ( ad ) in the elderly , controversy remai... | cerebrovascular disease is the second leading cause of cognitive impairment in the elderly , either alone or in combination with alzheimer 's disease ( ad ) .
vascular dementia ( vad ) is heterogeneous in terms of both clinical phenotype and pathogenetic mechanisms .
it may result from multiple cortical infarctions... |
extrahepatic biliary duct duplication , also commonly called duplicated common bile duct ( dcbd ) , is exceptionally rare and mostly turn to be unexpected finding during surgery exposing surgeons to unusual surprises leading to iatrogenic bile duct injuries ( bdi ) .
this anomaly has been reported to be associated wi... | abstractduplicated common bile duct , often associated with conditions like lithiasis , biliary cysts and pancreatobiliary maljunction , could result in highly morbid and potentially fatal biliary injuries .
precise preoperative diagnosis and classification still remain a challenge . a female patient undergoing emerg... |
firstly , a child 's eye continues to grow during the initial years of life and early childhood .
refractive elements of the eye undergo radical changes ; axial elongation and changes in corneal curvature are major factors influencing refractive changes in early childhood .
for instance average corneal curvature fl... | there are several reasons for which the correction of aphakia differs between children and adults .
first , a child 's eye is still growing during the first few years of life and during early childhood , the refractive elements of the eye undergo radical changes .
second , the immature visual system in young childr... |
insects exhibit symbiotic relationships with bacteria and they provide several benefits to their host .
essential insect symbionts offer a desirable target for the control of insect pests that rely upon them .
the complete elimination of endosymbionts using antibiotics reduces the lifespan of the insect and suppr... | the mealy bug , rhizoecus amorphophalli , is a menace to the aroid farmers due to the intensive infestation on stored tubers .
spraying of pesticides was able to control this pest but it always left a chance for fungal growth .
bacterial endosymbionts associated with the insects provide several benefits to their ho... |
asthma is a chronic inflammatory airway disorder characterized by airway hyper - responsiveness , reversible airway obstruction , and airway remodeling .
it is commonly thought that asthma is a multi - factorial disease resulting from complex interactions between genetic predisposition and environmental factors .
s... | backgroundconflicting data have been reported on the association between toll - like receptor 4 ( tlr4 ) + 896a / g and + 1196c / t polymorphisms and the risk of asthma . therefore , we conducted this meta - analysis to clarify the effect of tlr4 + 896a / g and + 1196c / t polymorphisms on the risk of asthma.material/m... |
one of the adverse events associated with serotonergic agents is serotonin syndrome ( ss ) .
the development of ss can be caused not only by an overdose of serotonergic agents but also through an interaction with other drugs ( 1,2 ) .
it is has been reported that more than 85% of physicians are not aware of ss ( 3 ... | a 40-year - old woman with bipolar disorder who was taking mirtazapine presented with mydriasis , abnormal diaphoresis , myoclonus and muscle rigidity after taking metocloplamide . her medical history , which included the use of serotonergic agents , and the presence of symptoms including
myoclonus and muscle rigidit... |
wegener s granulomatosis ( wg ) , first described by friedrich wegener in stuttgart in 1936 , is multi - system disease characterized by a necrotizing granulomatous arteritis of the upper and lower respiratory tract and a necrotizing crescentic glomerulonephritis .
vasculitis may also affect other organs such as the ... | wegener s granulomatosis ( wg ) frequently involves the subglottis and trachea and may compromise the upper airway .
the objective of this study is to evaluate retrospectively the effect of treatment of subglottic stenosis ( sgs ) and tracheal stenosis ( ts ) by dilatation tracheoscopy ( dt ) in patients with wg .
... |
oral cancer is the eleventh most prevalent cancer worldwide . oral cancers in australia account for approximately 2 - 3% of all cancers and approximately 1% of all cancer deaths , with an increasing incidence over the past decades .
the most common oral cancer is oral squamous cell carcinoma ( oscc ) , which makes up... | chemokines have been shown to be important in both inflammation and carcinogenesis and are able to be measured in saliva with relatively robust methods including enzyme - linked immunosorbent assays ( elisa ) . thus it has been hypothesized that patients with oral cancer and oral potentially malignant lesions will have... |
the who regional committee of the western pacific about a new bmi for asians defined
23 kg / m or higher bmi as overweight , and 25 kg / m or higher as
obesity1 .
it is associated with
increased body fat , bmi , and waist measurements , which adversely affect the activities in
daily living and physical acti... | [ purpose ] to suggest physiotherapy programs and to determine foot stability based on the
results of plantar pressure and spontaneity balance in the normal group and in the obesity
group according to the body mass index ( bmi ) .
[ subjects and methods ] the plantar pressure
and balance of 20 females college s... |
diabetic nephropathy ( dn ) is one of the most serious microvascular complications of diabetes , which is the leading cause of end - stage renal disease .
previous studies have reported that podocytes are highly differentiated , insulin - dependent glomerular epithelial cells contributing to glomerular filtration bar... | podocalyxin ( pcx ) is a signature molecule of the glomerular podocyte and of maintaining integrity of filtration function of glomerulus .
the aim of this study was to observe the effect of different doses of metformin on renal tissue pcx expression in type 2 diabetic rats and clarify its protection on glomerular pod... |
critical illness may occur at any time of life , having permanent effects not only on
one?s health but on other aspects of life , including spiritual , social , and familiar
issues . despite this , mortality is still the most frequently assessed outcome in
critically ill patients and is routinely used as the prim... | mortality is still the most assessed outcome in the critically ill patient and is
routinely used as the primary end - point in intervention trials , cohort studies , and
benchmarking analysis . despite this , interest in patient - centered prognosis after icu
discharge is increasing , and several studies report q... |
the bacterial plaque has been implicated as the primary etiologic factor in inflammatory periodontal disease , but recently , several studies have focused on the role of the immune system in the evolution of the periodontal disease , indicating that bacterial antigens trigger an immunopathologic reaction and that the s... | aims and objectives : the aim of this study was to evaluate and correlate the relationship between mast cells counts and different stages of human periodontal diseases.materials and methods : the study sample comprised 50 patients , which were divided into three groups , consisting of 10 cases of clinically healthy gin... |
blindness is one of the most prevalent disabilities worldwide which is known as one of the most severe health conditions affecting individuals , families and communities . according to the latest world health organization ( who ) estimates in 2010 , approximately 39 million people in the world were blind . as revealed ... | background : vision impairment in children is one of the most severe disabilities that cause stress in parents .
therefore , it seems necessary to establish and conduct interventions for controlling parenting stress and preventing its negative consequences .
this study aimed to investigate the effect of life skills... |
a ti : sapphire laser at 830 nm ( 80 mhz , ~140 fs pulse width , chameleon , coherent , ca ) pumped an optical parametric oscillator ( opo , ape , coherent , ca ) , providing a 1064 nm output with ~260 fs pulse width . the 1064 nm beam
the pump beam was modulated by an acousto - optic modulator ( aom , gooch & houseg... | super - resolution optical microscopy is opening a new window to unveil the unseen details on the nanoscopic scale .
current far - field super - resolution techniques rely on fluorescence as the read - out15 . here
, we demonstrate a scheme for breaking the diffraction limit in far - field imaging of non - fluoresc... |
to describe the work - up and treatment of rare ectopic acromegaly caused by a biopsy - proven somatotroph pituitary adenoma located within the bony intersphenoid septum of a patient with empty sella syndrome ( ess ) .
we report the presentation , clinical course , diagnostic work - up , and lesion localization and t... | objective
to describe the work - up and treatment of rare ectopic acromegaly caused by a biopsy - proven somatotroph pituitary adenoma located within the bony intersphenoid septum of a patient with empty sella syndrome ( ess).methods
we report the presentation , clinical course , diagnostic work - up , and lesion l... |
the isolation and study of reactive intermediates provides a wealth
of insights into the mechanism and stereochemical course of synthetically
useful reactions .
of course , many intermediates are not amenable to
isolation because of their instability , reactivity or other complicating
factors . in these cases... | through
the combination of reaction kinetics ( both catalytic and
stoichiometric ) and solid - state characterization of arylpalladium(ii )
alkenylsilanolate complexes , the intermediacy of covalent adducts
containing si o pd linkages in the cross - coupling reactions
of organosilanolates has been unambiguo... |
end - stage renal disease ( esrd ) is associated with higher incidence of pulmonary arterial hypertension ( pah ) , leading to increased chances of mortality , morbidity and early rejection in patients slated for renal transplantation .
the prevalence of pah among the patients receiving long - term haemodialysis ( hd... | we describe a patient with severe pulmonary arterial hypertension scheduled to undergo live - related renal transplantation .
we emphasise on meticulous anaesthetic management and early renal transplantation to prevent the progression of disease which would become refractory to treatment , leading to right ventricula... |
a significant number of patients with diabetes remain poorly controlled , mainly as a result of poor diet compliance .
the important choices that affect blood glucose control in people with diabetes are made by themselves , and not by their physicians or other medical professionals .
people with diabetes are advise... | the aim of this review was to evaluate whether eating vegetables before carbohydrates could reduce the postprandial glucose , insulin , and improve long - term glycemic control in japanese patients with type 2 diabetes .
we studied the effect of eating vegetables before carbohydrates on postprandial plasma glucose , ... |
by the age of 80 years , humans generally lose 3040% of their skeletal muscle fibers , particularly type ii fibers .
the decline in muscle mass and strength with age is well documented.2 , 3 in general , the muscle mass of 6070-year - olds decreases to 7080% of that of younger people ( < 60 years old).4 , 5 the main... | recent studies have focused on evidence - based interventions to prevent mobility decline and enhance physical performance in older adults .
several modalities , in addition to traditional strengthening programs , have been designed to manage age - related functional decline more effectively . in this study
, we re... |
liver cirrhosis ( lc ) is a major , life - threatening health problem worldwide .
lc results from liver injuries of numerous different etiologies , causing hepatocyte damage , hepatic inflammation , and fibrogenesis .
lc is histologically characterized by increased deposition in and altered composition of the extra... | liver cirrhosis , a late stage of hepatic fibrosis , is an increasing cause of morbidity and mortality worldwide .
hepatic fibrosis is mainly caused by alcoholic or non - alcoholic steatohepatitis , chronic viral hepatitis , or autoimmune and biliary diseases .
myofibroblasts , which are absent from the normal live... |
the neural - cadherin ( cdh2 ) gene encodes the n - cadherin protein , a member of the cadherin gene family that mediates cell adhesion , differentiation , embryogenesis , and invasion1 .
it has been described in a number of organs1,2 and malignancies derived from these3,4,5 . although the distribution of n - cadheri... | neural - cadherin is a member of the cadherin gene family encoding the n - cadherin protein that mediates cell adhesion .
n - cadherin is a marker of sertoli cells and is also expressed in germ cells of varying stages of maturation .
the purpose of this study was to determine the presence and distribution of this p... |
phosphotyrosine phosphatases ( ptps ) serve as important regulators of cellular signal transduction pathways .
ptps are sensitive targets of oxidative stress and may be inhibited by treatments that induce intracellular oxidation .
the effects of ptp inactivation under oxidizing conditions are amplified by the redox... | |
supraclavicular brachial plexus block is a common regional anesthetic technique used to provide anesthesia and analgesia for upper extremity surgery at our institution .
-2 adrenoreceptor agonists have been the focus of interest for their sedative , analgesic , and perioperative sympatholytic and cardiovascular stabi... | background and aims : various additives are mixed with local anesthetic agents to increase the quality of block in regional anesthesia .
we compared clonidine and dexmedetomidine as an adjunct to bupivacaine in supraclavicular brachial plexus block with respect to the onset and duration of sensory and motor block and... |
this article describes the curation workflow for xenbase ( www.xenbase.org ) ( 1,2 ) and was presented as part of the biocreative workshop 2012 track ii .
xenbase is a large - scale model organism database ( mod ) and community resource for researchers working with the frog species , xenopus tropicalis and xenopus la... | xenbase ( www.xenbase.org ) is the model organism database for xenopus tropicalis and xenopus laevis , two frog species used as model systems for developmental and cell biology .
xenbase curation processes centre on associating papers with genes and extracting gene expression patterns .
papers from pubmed with the ... |
neuropathic pain is an umbrella term that has recently been redefined by the international association for the study of pain as pain caused by a lesion or disease of the somatosensory system,1 thereby encompassing a number of diverse conditions and body sites . although largely underappreciated , the vulva is a particu... | the vulva is a particularly common locus of chronic pain with neuropathic characteristics that occurs in women of any age , though most women with neuropathic type chronic vulvar pain will remain undiagnosed even following multiple physician visits . here
, we report on an exemplary case of a middle - aged woman who ... |
although the basic structure of the spindle is similar in all cell types of higher eukaryotes , spindle assembly can occur through different pathways . in most animal somatic cells , spindle formation
is mediated by a pair of microtubule ( mt ) * organizing centers , called the centrosomes . during prophase ,
the s... | alarge body of work indicates that chromosomes play a key role in the assembly of both acentrosomal and centrosome - containing spindles . in animal systems , the absence of chromosomes either prevents spindle formation or allows the assembly of a metaphase - like spindle that fails to evolve into an ana - telophase sp... |
a 61-year - old male patient presented to our institution with a complaint of pain in the right knee that had aggravated for the last three days . on the same knee , he underwent posterior cruciate ligament ( pcl ) reconstruction surgery due to trauma seven years prior and tka due to rheumatoid arthritis four years pre... | streptococcus dysgalactiae subspecies dysgalactiae ( sdsd ) , lancefield group c streptococcus , is an animal pathogen which often causes pyogenic infection in domestic animals .
human infection by sdsd has been reported as a cellulitis on the upper arm , but a prosthetic joint infection caused by sdsd after total kn... |
severe coronary artery calcifications ( cacs ) present an ongoing treatment challenge despite the advent of various technologies for plaque debulking and reducing atherosclerotic burden prior to stent implantation .
the diamondback 360 coronary orbital atherectomy ( oa ) system ( cardiovascular systems inc . , st .
... | severe coronary artery calcifications pose an ongoing challenge when performing percutaneous coronary interventions , resulting in an increased likelihood of procedural complications .
orbital atherectomy ( oa ) has emerged as a promising technology that helps improve outcomes in this complex patient population .
i... |
isolated subcutaneous preadipocytes from lean ( bmi < 25 ) and obese ( bmi > 30 ) subjects ( zen - bio , research triangle park , nc ) were plated on t-75 cell culture flasks and cultured at 37c and 5% co2 in dulbecco 's modified eagle 's medium ( dmem)/nutrient mix f-12 medium ( 1:1 , v / v ) supplemented with 10u / m... | objectivemetformin has been well characterized in vitro as a substrate of liver - expressed organic cation transporters ( octs ) .
we investigated the gene expression and protein levels of oct-1 and oct-2 in adipose tissue and during adipogenesis and evaluated their possible role in metformin action on adipocytes.res... |
patients were recruited as part of the cdc emerging infections program s unex study and met all project inclusion criteria , including absence of important preexisting medical conditions , development of an illness with defined features suggestive of infectious etiology , severity leading to admission to an intensive c... | broad - range rdna polymerase chain reaction ( pcr ) provides an alternative , cultivation - independent approach for identifying pathogens . in 1995 , the centers for disease control and prevention initiated population - based surveillance for unexplained life - threatening infections ( unexplained death and critical ... |
this work was supported by the national 863 project ( no : 2002aa302608 ) , from the ministry of science and technology , china . | in this paper , the initial susceptibility of -fe3n magnetic fluid at volume concentrations in the range = 0.0 0.0446 are measured .
compared with the experimental initial susceptibility , the langevin , weiss and onsager susceptibility were calculated using the data obtained from the low concentration -fe3n magnet... |
eating disorders have been defined as characterized by persistence disturbance of eating or eating - related behavior that results in the altered consumption or absorption of food and that significantly impairs health or psychosocial functioning.1 the last version of the diagnostic and statistical manual of mental dis... | eating disorders have been defined as characterized by persistence disturbance of eating or eating - related behavior that results in the altered consumption or absorption of food and that significantly impairs health or psychosocial functioning .
the psychopathology of eating disorders changed across time under th... |
a recent survey from
the centers for disease control and prevention
indicates that diabetes affects 25.8 million people in the united
states which is 8.3% of the u.s .
most diabetic patients will ultimately develop kidney failure , hypertension ,
and/or suffer stroke .
in addition , about two - thirds of di... | diabetes
is affecting the life of millions of people .
a large proportion
of diabetic patients suffer from severe complications such as neuropathic
pain , and current treatments for these complications have deleterious
side effects .
thus , alternate therapeutic strategies are needed .
recently ,
the el... |
the nature of the effects of higher - order corneal aberrations on lower - order corneal astigmatism has until now been poorly understood .
if the corneal astigmatism differed from the manifest astigmatism , it was usually diagnosed as lenticular astigmatism through a process of exclusion .
some authors have also p... | purposeto demonstrate how higher - order corneal aberrations can cancel out , modify , or induce lower - order corneal astigmatism.patients and methodssix representative eyes are presented that show different scenarios in which higher - order aberrations interacting with corneal astigmatism can affect the manifest refr... |
d - myo - inositol
1,4,5-trisphosphate receptors
( ip3rs ) are ca channels located on the endoplasmic
reticulum . ip3
[ ins(1,4,5)p3 , 1 ] is a second messenger produced by the action
of phospholipase c on phosphatidylinositol 4,5-bisphosphate in response
to various extracellular signals .
ip3 binds to it... | although adenophostin a ( ada ) , the most potent agonist
of d - myo - inositol 1,4,5-trisphosphate receptors
( ip3r ) , is thought to mimic ip3 , the relative
roles
of the different phosphate groups and the adenosine motif have not
been established .
we synthesized all three possible bisphosphate analogues... |
anti - mllerian hormone ( amh ) , also known as mller inhibiting factor or mller inhibiting substance , is a glycoprotein formed from two identical subunits , each with a molecular weight of 72 kda .
the hormone is part of the growth factor family , which includes 35 different peptide structures , including inhibi... | backgroundthe anti - mllerian hormone ( amh ) is a dimeric protein secreted by the female ovaries and has two fundamental roles in follicle genesis .
it delays the entrance of the primordial follicle into the pool of follicles in growth and diminishes the sensitivity of the ovarian follicle towards follicle - stimula... |
this is achieved through physical postures ( asanas ) , breathing techniques ( pranayama ) , and meditation ( dhyana ) .
yoga is emerging as an important modifying factor for health and behavior to achieve better physical and mental well - being .
the practice of asanas improves the muscle strength , mind - body co... | background : yoga is a science that facilitates homeostasis , an ancient way of life intended to improve the quality of life of an individual . practice of yoga is proposed to alter the autonomic nervous system and affect the cardiovascular functioning .
this study was intended to assess the influence of short - term... |
fungal peritonitis ( fp ) is a rare but potentially fatal complication of chronic peritoneal dialysis ( pd ) , associated with high morbidity and mortality ranging between 20% and 30% .
fp accounts for 1 - 15% of all peritonitis episodes . in those who survived peritonitis ,
the inflammatory process often causes ir... | fungal peritonitis ( fp ) is a rare , but serious complication of peritoneal dialysis .
we analyzed the incidence of fp , associated risk factors and outcome of patients with fp and evaluated the role of prophylactic antifungal agent in reducing its incidence .
we studied all patients with fp from january 2005 to j... |
actomyosin contraction provides the force - driving contraction , membrane blebbing and apoptotic body formation during programmed cell death.apoptotic cells display cell surface markers that facilitate recognition and uptake by phagocytic cells.impaired apoptotic cell clearance may contribute to inflammation and autoi... | apoptotic cell clearance facilitates the removal of aged , damaged , infected or dangerous cells although minimizing perturbation of surrounding tissues , and is a vital process in the development and homeostasis of multicellular organisms .
importantly , failure to correctly execute programmed cell death and subsequ... |
tuberculous meningitis ( tbm ) is among the most fatal forms of extrapulmonary tuberculosis ( eptb ) accounting for 7080% of all neurological tb cases [ 24 ] .
the development of tbm infection occurs with infection of meninges with tuberculous bacilli , resulting in formation of tuberculous lesions ( rich foci ) .
... | the present study was designed to investigate rv2623 antigen , a major dormancy regulon protein of mycobacterium tuberculosis ( mtb ) in csf of suspected latent and active tuberculous meningitis ( tbm ) patients . a total of 100 csf samples from tbm ( n = 31 ) , suspected latent tbm ( n = 22 ) , and suitable noninfecti... |
duplications leading to functional disomy of chromosome xq28 are associated with a distinct clinical phenotype in males , characterized by severe mental retardation , infantile hypotonia , progressive neurologic impairment , recurrent infections , bladder dysfunction , and absent speech ( see and for reviews ) .
... | duplications leading to functional disomy of chromosome xq28 , including mecp2 as the critical dosage - sensitive gene , are associated with a distinct clinical phenotype in males , characterized by severe mental retardation , infantile hypotonia , progressive neurologic impairment , recurrent infections , bladder dysf... |
total knee arthroplasty ( tka ) is a surgery that improves patient mobility and quality of life , but causes severe postoperative pain during the first 2472 hours.1 adequate postoperative pain control promotes patient ambulation and physiotherapy,2 leading to early recovery , fewer complications ( ie , deep - vein thro... | purposeto assess the efficacy of a transdermal fentanyl patch ( tfp ) ( 50 g / hour ) applied 1012 hours before surgery versus placebo for postoperative pain control of total knee arthroplasty ( tka).materials and methodswe enrolled 40 patients undergoing elective tka under spinal anesthesia using isobaric or hyperbari... |
pancreatic tuberculosis ( tb ) is a rare condition affecting those from endemic areas as well as those with immunocompromise.1 within the past decade , there has been an increase in the number of cases reported within the united states.2345 we report a case of pancreatic tb in a young female that initially presented as... | a female presented to the physician with a history of right upper quadrant pain . abdominal computed tomography ( ct ) scan dem - onstrated a multi - loculated solid lesion in the head of the pancreas concerning for a primary malignancy .
endoscopic ultrasound - guided fine needle aspiration ( eus - fna ) of the lesi... |
the recent boom in genome - wide association ( gwa ) studies has resulted in a vast expansion of our knowledge of common variants influencing human diseases . so far ,
1,888 single nucleotide polymorphism ( snp ) associations have been reported , 1,435 of which are unique to the snp .
they account for only 36 publi... | plausible genome - wide associations for episodic neurological diseases ( such as migraine , epilepsy and ataxias ) have been slow to emerge .
the first such association was reported in a recent genome - wide association study of migraine , with quantitative expression analysis linking the variant to a nearby regulat... |
microorganisms are responsible for development of many diseases , which directly or indirectly affect reproductive performance in various animal species .
knowledge of the microflora of animal skin and mucous membranes is essential for better understanding of pathological processes .
, in cows , these include candi... | the aim of the study was a quantitative and qualitative analysis of microflora , presentation of current data about prevalence of the microflora on the skin and mucous membranes , and determination of its possible effect on reproduction of english full blood horses bred in poland .
the material for analyses was sampl... |
azoxymethane ( aom )
and its metabolic precursor , 1 , 2-dimethylhydrazine
( dmh ) , are commonly used carcinogens to study the molecular mechanisms
of colon carcinogenesis in rodents .
they are preferred model carcinogens because
they induce tumors preferentially in the distal colon of rodents and
because ... | p450-mediated
bioactivation of azoxymethane ( aom ) , a colon carcinogen ,
leads to the formation of dna adducts , of which o6-methylguanine ( o6-mg ) is the most mutagenic
and contributes to colon tumorigenesis . to determine whether p450
enzymes of the liver and intestine both contribute to aom bioactivation ... |
neonatal respiratory failure is a serious clinical problem[13 ] associated with high morbidity , mortality , and cost[46 ] .
the major risk factor is low birth weight[7 , 8 ] , which is more prevalent among the poor , and the uninsured[912 ] .
the standard method of management for respiratory failure is supportive ... | objectiveapplication of continuous positive airway pressure ( cpap ) in neonate with respiratory distress is associated with reduction of respiratory failure , reduced complications and mortality .
bubble cpap ( b - cpap ) and ventilator - derived cpap ( v - cpap ) are two most popular cpap modes .
we aimed to dete... |
the present study was carried out on 150 professional mbbs students of tertiary care hospital .
students were briefed about the purpose of the study and informed written consent was obtained .
a pretest was conducted by giving 10 questions of general awareness and 15 questions regarding pharmacotherapy of hiv / aid... | objective : medical students as future doctors will play an important role in caring for hiv - infected patients .
this study assessed and evaluated the existing level of knowledge of mbbs students about hiv / aids given through lecture delivery methods and by use of concept map ( cm).materials and methods : this stu... |
pulmonary surfactant is a lipoprotein complex composed of lipids ( 90% ) and proteins ( 10% ) , secreted by the alveolar type ii pneumocytes , that reduces the surface tension of fluids that coat alveoli , maintaining the stability of alveolar structures .
surfactant proteins include surfactant protein a ( spa ) , b ... | the surfactant complex , thanks to its multiple actions including decrease of surface - tension and antimicrobial activity , plays a fundamental role in newborn survival , lowering the risk of respiratory distress syndrome .
the aim of this work was to determine if the synthesis of two surfactant proteins ( sp ) , sp... |
most case reports are of ingestion of sharp objects that can be retrieved by indirect laryngoscopy or flexible endoscopy in the majority of cases .
foreign bodies have been found to migrate to the pancreas from the gastrointestinal ( gi ) tract .
presentation varies widely from a 45-year - old man who was asymptoma... | we present a case report of a laparoscopically retrieved foreign body that migrated into the pancreas .
the patient is a 44-year - old man who presented with epigastric pain and was subsequently found by computed tomographic scan to have a foreign body in the head of the pancreas .
after attempted endoscopic retrie... |
in 2011 in cambodia , environmental samples were collected from 4 lpms each week for 7 weeks , including during the khmer new year festival ( figure 1 ) .
two of the markets were in phnom penh , the capital city : orussey market ( m1 ) and chamkar doung market ( m2 ) , which also served as an overnight resting place ... | in cambodia , influenza a(h5n1 ) virus surveillance at live poultry markets ( lpms ) relies on virus isolation from poultry specimens ; however , virus is rarely detected by this method .
we tested 502 environmental lpm samples : 90 were positive by pcr , 10 by virus isolation .
virus circulation could be better mo... |
we used commercial single - layer graphene samples ( ted pella inc . ,
redding / ca 21712 - 5 pelco ) grown with chemical vapor deposition and
deposited on sinx transmission electron
microscopy grids with a regular pattern of holes with an approximate
diameter of 2.5 m .
fully and partially
sputtered areas ... | graphene
has many claims to fame : it is the thinnest possible membrane , it
has unique electronic and excellent mechanical properties , and it
provides the perfect model structure for studying materials science
at the atomic level .
however , for many practical studies and applications
the ordered hexagon ... |
worldwide , colorectal cancer is the fourth most common cancer in men and the third most common cancer in women .
each year more than 1 million new diagnoses are made and more than 500,000 die of the disease ( 1 ) .
similarly , in korea , colorectal cancer is a major cause of morbidity and mortality .
the majorit... | the aims of this study were to review the clinicopathological characteristics of diminutive ( 5 mm ) and small polyps ( > 5 mm but < 10 mm ) and to evaluate the risk factors of advanced adenoma for polyps of diameter < 10 mm in the colon .
the medical records of 4,711 patients who underwent first colonoscopy at outp... |
pancreatic cancer is one of the most lethal malignant diseases of the gastrointestinal system and curative resection in pancreatic cancer is essential for long - term survival . with the advance of surgical techniques and perioperative management , conventional pancreatectomy , such as distal pancreatectomy or pancreat... | postoperative pancreatic fistula ( popf ) combined with postoperative fluid collection , bleeding and abscess formation is one of the most critical morbidities after distal pancreatectomy or pancreaticoduodenectomy .
percutaneous catheter drainage has been commonly used for managing for the postoperative management o... |
small organic osmolytes are molecules
that virtually all organisms
use to counter cellular stresses . many
of these molecules are known to have a profound impact on biological
macromolecules and are thus of broad research interest .
a debate has been going
on for decades about the mechanism of the action of... | virtually all taxa use osmolytes
to protect cells against biochemical
stress .
osmolytes often occur in mixtures , such as the classical combination
of urea with tmao ( trimethylamine n - oxide ) in cartilaginous
fish or the cocktail of at least six different osmolytes in the kidney .
the concentration patt... |
it is well known that a decreased heart rate variability leads to increased cardiovascular risk , particularly to an increased arrhythmic risk both in patients with cardiovascular disease and healthy subjects . in the presence of cardiac autonomic neuropathy ,
diabetic patients with or without cardiovascular disease ... | background and aimsthe aim of this study is to identify and highlight the relationship between serum lipid fractions and heart rate variability in diabetic patients receiving statin therapy.patients and methodsthe study was performed in a group of 87 type 2 diabetic patients on statin associated therapy .
all patient... |
appendicitis is an inflammation of the appendix , that comprises approximately 25% of the surgical emergency admissions and 40% of the total laparotomy emergencies .
the standard treatment for acute appendicitis is the surgical removal of the appendix called appendectomy this may be done by an open incision in the ab... | background : laparoscopic appendectomy is a well - described surgical technique .
however , concerns still exist regarding whether the closure of the appendiceal stump should be done with a clip , an endoloop , or other techniques . in this study ,
the effect of stump closure on duration of surgery and complication... |
the neuro - cardio - facial - cutaneous syndromes consist of neurofibromatosis type 1 , noonan , leopard , costello and cardio - facio - cutaneous ( cfc ) syndromes .
psychomotor retardation , congenital heart diseases ( chd ) , facial abnormalities , short stature , skin problems and cancer predisposition are common... | congenital heart diseases are a major part of costello and cardio - facio - cutaneous syndromes .
subaortic stenosis was reported rarely and ross operation never in these syndromes.we reported a girl patient whose manifestations were consistent with these syndromes .
distinction between these syndromes was not poss... |
colon diverticulosis is a frequent condition in adults in western countries and several patients experience clinical symptoms even when diverticulosis is not complicated by diverticulitis .
udd symptoms pathogenesis remains unknown , but alterations in the diet and gut microbiota may be involved and could be responsi... | background / aim . uncomplicated diverticular disease ( udd ) is a frequent condition in adults .
the pathogenesis of symptoms remains unknown .
bacteria are able to interact with toll - like receptors ( tlrs ) and to induce inflammation through both innate immunity and t - cell recruitment .
we investigated the ... |
thyroid carcinoma is the most common endocrine neoplasm and is increasing worldwide ( in the usa , 8.7 per 100,000 people ) [ 14 ] .
papillary thyroid carcinomas ( ptcs ) accounted for 74% of all thyroid carcinomas in 1973 and 87% in 2003 . in this period ,
its incidence ( including that of the follicular variant o... | background . molecular diagnostics has offered new techniques for searching for mutations in thyroid indeterminate lesions . the study 's aim was to evaluate the braf mutations ' incidence in an italian regional population .
subjects and methods .
70 caucasian patients born in liguria with indeterminate or suspicio... |
3 mm 3 mm wedges were prepared from single crystal copper with a ( 100 ) orientation ( mateck gmbh , juelich , germany ) , using mechanical and electrochemical polishing .
the subsequent experimental procedure is shown in fig . 1 : a 5 m thick and 200 m long lamella was machined out of the single crystal wedge using... | increasing demand for energy and reduction of co2 emissions has revived interest in nuclear energy . designing materials for radiation environments
necessitates fundamental understanding of how radiation - induced defects alter mechanical properties .
ion beams create radiation damage efficiently without material a... |
to describe a patient with behet 's disease and anterior uveitis , which was not cured by local and systemic corticosteroid treatments , who underwent trabeculotomy one week after infliximab administration .
neither ocular inflammatory attacks nor infectious complications were found in the operated eye of the pati... | purposeto describe a patient with behet 's disease and anterior uveitis , which was not cured by local and systemic corticosteroid treatments , who underwent trabeculotomy one week after infliximab administration.methodsthe patient received preoperative antibiotic therapy followed by trabeculotomy one week after inflix... |
cardio ankle vascular index ( cavi ) , an indicator of the overall stiffness of the artery from the origin of the aorta to the ankle , is elevated in patients who have coronary risk factors .
both organic and functional factors are thought to be associated with arterial stiffness assessed by cavi , and the latter ca... | the cardio ankle vascular index ( cavi ) is an indicator of arterial stiffness from the heart to the ankles . the cavi increases as arteriosclerosis progresses , but it can be decreased by appropriate treatment .
there are several risk factors for coronary artery disease , however , the degree of stress caused by ea... |
extracellular electron transfer for respiration of insoluble oxide minerals by microbes is important for the biogeochemical cycling of metals , biotechnology , and bioremediation and may represent the earliest form of respiration on earth ( 1 ) . in natural environments ,
microorganisms catalyze the breakdown of orga... | abstractshewanella oneidensis strain mr-1 is widely studied for its ability to respire a diverse array of soluble and insoluble electron acceptors . the ability to breathe insoluble substrates
is defined as extracellular electron transfer and can occur via direct contact or by electron shuttling in s. oneidensis . t... |
many approaches have been used to prepare oral formulations of poorly water - soluble drugs to improve oral bioavailability.13 among them , solid dispersion ( sd ) , in which the drug molecule is dispersed in a polymeric matrix , has been shown to improve the aqueous solubility and oral absorption of drugs.4,5 sd produ... | backgroundsoluplus ( sp ) and d - alpha - tocopherol polyethylene glycol 1000 succinate ( tpgs)based solid dispersion ( sd ) formulations were developed by hot - melt extrusion ( hme ) to improve oral bioavailability of valsartan ( vst).methodshme process with twin - screw configuration for generating a high shear stre... |
pollution of natural waters with waste water arising from various industries has become a serious problem globally .
textile industries are large industrial consumers of waters as well as producers of wastewaters with the increased demand for textile products leading to increase in the generation of textile wastewate... | the study was conducted in 2013/14 with the objective of determining the effects of bahir dar textile factory effluents on the head of blue nile river water quality .
dissolve oxygen was higher at the upstream site of the river , whereas bod5 , tds , and total alkalinity values were higher at wastewater outlet of the... |
zinc is an essential element for all cells , as it is used as a cofactor for many enzymes and transcription factors that mediate key cellular processes , such as protection against oxidative stress , deoxyribonucleic acid ( dna ) repair , dna replication , proliferation , differentiation and apoptosis .
the total zin... | abstractzinc is an essential nutrient with tremendous importance for human health , and zinc deficiency is a severe risk factor for increased mortality and morbidity . as abnormal zinc homeostasis causes diabetes , and because the pancreatic cell contains the highest zinc content of any known cell type , it is of inter... |
periodontitis is a chronic inflammatory disease characterized by destruction of tooth - supporting tissues . the red - complex bacteria including , porphyromonas gingivalis , tannerella forsythia and treponema denticola were shown to have the closest association with the severity of periodontitis [ 2 , 3 ] besides this... | objectives . this study evaluated il-17 and il-11 in gingival crevicular fluid ( gcf ) of generalized chronic periodontitis ( gcp ) and generalized aggressive periodontitis ( gagp ) patients in relation to periodontopathic bacteria . subjects and methods .
gcf samples were collected from 65 subjects including 25 cp ,... |
many
processes in nature and technology involve polymer - decorated
surfaces in liquid media , and therefore understanding of interactions
between such surfaces is important from both academic and technological
points of view .
dense grafting of polymer chains to a surface leads
to the extension of these po... | we
develop a scaling model relating the friction forces between
two polyelectrolyte brushes sliding over each other to the separation
between grafted surfaces , number of monomers and charges per chain ,
grafting density of chains , and solvent quality .
we demonstrate that
the lateral force between brushes... |
b and t lymphocytes form the adaptive arm of the immune system in jawed vertebrates and can specifically respond to an astounding number of foreign antigens .
this property depends largely on a series of site - specific dna rearrangement events between separate v , d , and j gene segments at antigen receptor ( ar)-en... | v(d)j recombination assembles antigen - specific immunoglobulin and t - cell receptor variable region genes from germline v , d , and j segments during lymphocyte development .
regulation of this site - specific dna rearrangement process occurs with respect to the cell type and stage of differentiation , order of loc... |
head and neck cancers have a global annual incidence of about 560,000 new cases , and cause approximately 300,000 deaths per year throughout the world.1 while radical surgery is the most important treatment among the comprehensive therapies for head and neck cancers , radiotherapy has been extensively used as primary t... | osteoradionecrosis ( orn ) in the head and neck area is the most devastating long - term complication of radiotherapy , with slow progression and inability to heal spontaneously .
orn can lead to intolerable pain , fractures , and sequestration of devitalized bone and fistulae , making oral feeding impossible and cau... |
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